#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P60510	uniprotkb:Q8TF05	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1056262|uniprotkb:Q99774|uniprotkb:Q9UNQ7|ensembl:ENSP00000383402	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:pp4r1_human(display_long)|uniprotkb:PPP4R1(gene name)|psi-mi:PPP4R1(display_short)|uniprotkb:MEG1(gene name synonym)|uniprotkb:PP4R1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784784|imex:IM-25322-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_001035847.1|refseq:NP_005125.1|ensembl:ENSG00000154845(gene)|ensembl:ENST00000400556(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031087|interpro:IPR033461|mint:Q8TF05	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:c7WdQEzkeS6LDpC2GD9czxBdWj09606	rigid:J6UdWr29GhLOYyGe4rZe8z8tFDQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NY27	uniprotkb:Q5MIZ7	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	intact:EBI-720732|ensembl:ENSP00000483228|uniprotkb:Q6P9B0|uniprotkb:Q86XB8|uniprotkb:Q9BQJ0|uniprotkb:Q9BRK2|uniprotkb:Q9H913|uniprotkb:Q9P2G0	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:p4r3b_human(display_long)|uniprotkb:PPP4R3B(gene name)|psi-mi:PPP4R3B(display_short)|uniprotkb:KIAA1387(gene name synonym)|uniprotkb:PP4R3B(gene name synonym)|uniprotkb:SMEK homolog 2(gene name synonym)|uniprotkb:SMEK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784813|imex:IM-25322-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	refseq:NP_001269779.1|ensembl:ENSG00000275052(gene)|ensembl:ENST00000616407(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_065196.1|refseq:NP_001116436.2	-	-	-	figure legend:2Ai|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rogid:6vE7I6SP48sz9vvWezMslRsltgo9606	rigid:UNNmLmD5PhNGRye4J5lovcWOkUk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NY27	uniprotkb:P60510	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784813|imex:IM-25322-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:2Ai|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:UNNmLmD5PhNGRye4J5lovcWOkUk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NY27	uniprotkb:Q6IN85	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	intact:EBI-1055598|uniprotkb:Q69YK6|uniprotkb:Q86U23|uniprotkb:Q86YI7|uniprotkb:Q8IVG1|uniprotkb:Q9H3F1|uniprotkb:Q9H7U8|uniprotkb:Q9NV01|uniprotkb:Q9NWP1|ensembl:ENSP00000450883	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:p4r3a_human(display_long)|uniprotkb:PPP4R3A(gene name)|psi-mi:PPP4R3A(display_short)|uniprotkb:KIAA2010(gene name synonym)|uniprotkb:PP4R3A(gene name synonym)|uniprotkb:SMEK homolog 1(gene name synonym)|uniprotkb:SMEK1(gene name synonym)|uniprotkb:MSTP033(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784813|imex:IM-25322-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	refseq:NP_001271209.1|refseq:NP_001271210.1|refseq:XP_005267899.1|ensembl:ENSG00000100796(gene)|ensembl:ENST00000554943(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6R8I	-	-	-	figure legend:2Ai|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rogid:/Tc381stK9K9hy3AKtl1yNv9ajA9606	rigid:UNNmLmD5PhNGRye4J5lovcWOkUk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6IN85	uniprotkb:P60510	intact:EBI-1055598|uniprotkb:Q69YK6|uniprotkb:Q86U23|uniprotkb:Q86YI7|uniprotkb:Q8IVG1|uniprotkb:Q9H3F1|uniprotkb:Q9H7U8|uniprotkb:Q9NV01|uniprotkb:Q9NWP1|ensembl:ENSP00000450883	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:p4r3a_human(display_long)|uniprotkb:PPP4R3A(gene name)|psi-mi:PPP4R3A(display_short)|uniprotkb:KIAA2010(gene name synonym)|uniprotkb:PP4R3A(gene name synonym)|uniprotkb:SMEK homolog 1(gene name synonym)|uniprotkb:SMEK1(gene name synonym)|uniprotkb:MSTP033(orf name)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784823|imex:IM-25322-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271209.1|refseq:NP_001271210.1|refseq:XP_005267899.1|ensembl:ENSG00000100796(gene)|ensembl:ENST00000554943(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6R8I	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:2Aii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:/Tc381stK9K9hy3AKtl1yNv9ajA9606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:cwy9Q3fn01Vbm0ljsuuXpPN0DKI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6IN85	uniprotkb:Q9NY27	intact:EBI-1055598|uniprotkb:Q69YK6|uniprotkb:Q86U23|uniprotkb:Q86YI7|uniprotkb:Q8IVG1|uniprotkb:Q9H3F1|uniprotkb:Q9H7U8|uniprotkb:Q9NV01|uniprotkb:Q9NWP1|ensembl:ENSP00000450883	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	psi-mi:p4r3a_human(display_long)|uniprotkb:PPP4R3A(gene name)|psi-mi:PPP4R3A(display_short)|uniprotkb:KIAA2010(gene name synonym)|uniprotkb:PP4R3A(gene name synonym)|uniprotkb:SMEK homolog 1(gene name synonym)|uniprotkb:SMEK1(gene name synonym)|uniprotkb:MSTP033(orf name)	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784823|imex:IM-25322-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271209.1|refseq:NP_001271210.1|refseq:XP_005267899.1|ensembl:ENSG00000100796(gene)|ensembl:ENST00000554943(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6R8I	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	-	-	-	figure legend:2Aii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:/Tc381stK9K9hy3AKtl1yNv9ajA9606	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rigid:cwy9Q3fn01Vbm0ljsuuXpPN0DKI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5MIZ7	uniprotkb:P60510	intact:EBI-720732|ensembl:ENSP00000483228|uniprotkb:Q6P9B0|uniprotkb:Q86XB8|uniprotkb:Q9BQJ0|uniprotkb:Q9BRK2|uniprotkb:Q9H913|uniprotkb:Q9P2G0	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:p4r3b_human(display_long)|uniprotkb:PPP4R3B(gene name)|psi-mi:PPP4R3B(display_short)|uniprotkb:KIAA1387(gene name synonym)|uniprotkb:PP4R3B(gene name synonym)|uniprotkb:SMEK homolog 2(gene name synonym)|uniprotkb:SMEK2(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784874|imex:IM-25322-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269779.1|ensembl:ENSG00000275052(gene)|ensembl:ENST00000616407(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_065196.1|refseq:NP_001116436.2	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:2Aiii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:6vE7I6SP48sz9vvWezMslRsltgo9606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:8XnJLqJp8j8t1tKjWUIyoiQ38qM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5MIZ7	uniprotkb:Q9NY27	intact:EBI-720732|ensembl:ENSP00000483228|uniprotkb:Q6P9B0|uniprotkb:Q86XB8|uniprotkb:Q9BQJ0|uniprotkb:Q9BRK2|uniprotkb:Q9H913|uniprotkb:Q9P2G0	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	psi-mi:p4r3b_human(display_long)|uniprotkb:PPP4R3B(gene name)|psi-mi:PPP4R3B(display_short)|uniprotkb:KIAA1387(gene name synonym)|uniprotkb:PP4R3B(gene name synonym)|uniprotkb:SMEK homolog 2(gene name synonym)|uniprotkb:SMEK2(gene name synonym)	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784874|imex:IM-25322-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269779.1|ensembl:ENSG00000275052(gene)|ensembl:ENST00000616407(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_065196.1|refseq:NP_001116436.2	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	-	-	-	figure legend:2Aiii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:6vE7I6SP48sz9vvWezMslRsltgo9606	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rigid:8XnJLqJp8j8t1tKjWUIyoiQ38qM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75663	uniprotkb:P60510	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784882|imex:IM-25322-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:2Aiv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:t06SBvKpYXptIZLn4UHT/zoyXZM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75663	uniprotkb:Q9NY27	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784882|imex:IM-25322-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	-	-	-	figure legend:2Aiv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rigid:t06SBvKpYXptIZLn4UHT/zoyXZM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15297	uniprotkb:P60510	intact:EBI-1551512|uniprotkb:Q53XP4|uniprotkb:Q6P991|uniprotkb:Q8IVR6|ensembl:ENSP00000306682	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:ppm1d_human(display_long)|uniprotkb:Protein phosphatase 2C isoform delta(gene name synonym)|uniprotkb:p53-induced protein phosphatase 1(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 delta(gene name synonym)|uniprotkb:PPM1D(gene name)|psi-mi:PPM1D(display_short)|uniprotkb:WIP1(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784912|imex:IM-25322-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003611.1|dip:DIP-38281N|ensembl:ENSG00000170836(gene)|ensembl:ENST00000305921(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009314"(response to radiation)|go:"GO:0009617"(response to bacterium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR036457|reactome:R-HSA-8878166	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:2Av|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/21	rogid:U+O94qdtYTuxPdSe0pvO76cStf89606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:vogyN4oJI6axz1pqqx0vDHW19jw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P78318	uniprotkb:P60510	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11791792|imex:IM-25322-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/06/21	2016/06/29	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:POlr1kBAUvdY80HUwcWXGntmNqI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16104	uniprotkb:Q5MIZ7	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	intact:EBI-720732|ensembl:ENSP00000483228|uniprotkb:Q6P9B0|uniprotkb:Q86XB8|uniprotkb:Q9BQJ0|uniprotkb:Q9BRK2|uniprotkb:Q9H913|uniprotkb:Q9P2G0	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:p4r3b_human(display_long)|uniprotkb:PPP4R3B(gene name)|psi-mi:PPP4R3B(display_short)|uniprotkb:KIAA1387(gene name synonym)|uniprotkb:PP4R3B(gene name synonym)|uniprotkb:SMEK homolog 2(gene name synonym)|uniprotkb:SMEK2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784930|imex:IM-25322-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K	refseq:NP_001269779.1|ensembl:ENSG00000275052(gene)|ensembl:ENST00000616407(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|interpro:IPR006887(Protein of unknown function DUF625)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_065196.1|refseq:NP_001116436.2	go:"GO:0005634"(nucleus)	-	-	figure legend:4B|comment:"\"CPT\":- Camptothecin treatment  (CPT is a topoisomerase I inhibitor that induces formation of  H2AX foci) did not alter the localisation of PP4R3B or PP4R2 , which remained  mainly nuclear."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/06/21	2016/06/21	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	rogid:6vE7I6SP48sz9vvWezMslRsltgo9606	rigid:tEBM/VdUYM/eCs8U682MuV+k1sU	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P16104	uniprotkb:Q9NY27	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Chowdhury et al. (2008)	pubmed:18614045|imex:IM-25322	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11784944|imex:IM-25322-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	go:"GO:0005634"(nucleus)	-	-	figure legend:4C|comment:"\"CPT\":- Camptothecin treatment  (CPT is a topoisomerase I inhibitor that induces formation of  H2AX foci) did not alter the localisation of PP4R3B or PP4R2 , which remained  mainly nuclear."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/06/21	2016/06/21	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	rigid:Zfz42OIIf3LkCrt4wHRYrL7FBTU	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)