#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UK58-1 uniprotkb:Q9UQ88-1 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-11579223|ensembl:ENSP00000367900 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:q9uq88-1(display_long)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:p110(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580575|imex:IM-25069-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) intact:EBI-373024(isoform-parent)|ensembl:ENSG00000008128(gene)|ensembl:ENST00000378633(transcript) - - - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:h30ee1oqCuzFkWhpX9dsmJFl9Y09606 rigid:UIR75IoP+1w4dGyI0gkKgLnEdEI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96S94-1 uniprotkb:Q9UQ88-1 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-11579223|ensembl:ENSP00000367900 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:q9uq88-1(display_long)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:p110(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580585|imex:IM-25069-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) intact:EBI-373024(isoform-parent)|ensembl:ENSG00000008128(gene)|ensembl:ENST00000378633(transcript) - - - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:h30ee1oqCuzFkWhpX9dsmJFl9Y09606 rigid:3l2TjEN4iBdo+m5tZWlLj94aXQo false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96S94-2 uniprotkb:Q9UQ88-1 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-11579223|ensembl:ENSP00000367900 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:q9uq88-1(display_long)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:p110(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580599|imex:IM-25069-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) intact:EBI-373024(isoform-parent)|ensembl:ENSG00000008128(gene)|ensembl:ENST00000378633(transcript) - isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:h30ee1oqCuzFkWhpX9dsmJFl9Y09606 rigid:z99JFVNo7Eg7M7RfJ9yok/CLjjM false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UK58-4 uniprotkb:Q9UQ88-10 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-11580640 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:q9uq88-10(display_long)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:Beta 1(isoform synonym)|uniprotkb:p58(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580614|imex:IM-25069-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) intact:EBI-373024(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. isoform-comment:Produced by alternative initiation at Met-345 of isoform SV6. figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:49+q+Wp9+aei8ksKDVZAgxjUNjU9606 rigid:CaE573kxbjxuTXvToqulTkHBnfs false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96S94-1 uniprotkb:Q9UQ88-10 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-11580640 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:q9uq88-10(display_long)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:Beta 1(isoform synonym)|uniprotkb:p58(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580650|imex:IM-25069-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) intact:EBI-373024(isoform-parent) - - isoform-comment:Produced by alternative initiation at Met-345 of isoform SV6. figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:49+q+Wp9+aei8ksKDVZAgxjUNjU9606 rigid:eiRwME2HecZ8VLTtv2DFl+edXgw false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96S94-2 uniprotkb:Q9UQ88-10 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-11580640 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:q9uq88-10(display_long)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:Beta 1(isoform synonym)|uniprotkb:p58(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580658|imex:IM-25069-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) intact:EBI-373024(isoform-parent) - isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." isoform-comment:Produced by alternative initiation at Met-345 of isoform SV6. figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:49+q+Wp9+aei8ksKDVZAgxjUNjU9606 rigid:hKP5WPUReYlyEsHRwG0tTYdOWF4 false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UK58-1 uniprotkb:Q16629 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:Q07955 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:Q01130 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:P84103 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-372557|uniprotkb:P23152|uniprotkb:O08831|uniprotkb:B4E241|intact:EBI-11020748|uniprotkb:Q5R3K0|ensembl:ENSP00000362820|ensembl:ENSP00000482833 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:SRSF3(gene name)|psi-mi:SRSF3(display_short)|uniprotkb:SRP20(gene name synonym)|uniprotkb:SFRS3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) refseq:NP_003008.1|ensembl:ENSG00000112081(gene)|ensembl:ENST00000373715(transcript)|ensembl:ENST00000620941(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84103|rcsb pdb:2I2Y|rcsb pdb:2I38|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-32961N go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU9606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:Q13243 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:Q13247 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:Q08170 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580674|imex:IM-25069-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rigid:IvRD+hk78AfNU/izOBtBnxUyDLo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:Q16629 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:Q07955 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:Q01130 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:P84103 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-372557|uniprotkb:P23152|uniprotkb:O08831|uniprotkb:B4E241|intact:EBI-11020748|uniprotkb:Q5R3K0|ensembl:ENSP00000362820|ensembl:ENSP00000482833 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:SRSF3(gene name)|psi-mi:SRSF3(display_short)|uniprotkb:SRP20(gene name synonym)|uniprotkb:SFRS3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) refseq:NP_003008.1|ensembl:ENSG00000112081(gene)|ensembl:ENST00000373715(transcript)|ensembl:ENST00000620941(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84103|rcsb pdb:2I2Y|rcsb pdb:2I38|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-32961N go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU9606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:Q13243 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:Q13247 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-4 uniprotkb:Q08170 intact:EBI-11580622|ensembl:ENSP00000417237 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:q9uk58-4(display_long)|uniprotkb:cyclin L1beta(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L beta(isoform synonym) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580687|imex:IM-25069-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000470121(transcript) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:qjopbLPmhsfLJI6bhpJ2z3/gyvQ9606 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rigid:IThQZjdbMlHZlhE+6r73irId21M false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:Q16629 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:Q07955 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:Q01130 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:P84103 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-372557|uniprotkb:P23152|uniprotkb:O08831|uniprotkb:B4E241|intact:EBI-11020748|uniprotkb:Q5R3K0|ensembl:ENSP00000362820|ensembl:ENSP00000482833 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:SRSF3(gene name)|psi-mi:SRSF3(display_short)|uniprotkb:SRP20(gene name synonym)|uniprotkb:SFRS3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) refseq:NP_003008.1|ensembl:ENSG00000112081(gene)|ensembl:ENST00000373715(transcript)|ensembl:ENST00000620941(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84103|rcsb pdb:2I2Y|rcsb pdb:2I38|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-32961N go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU9606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:Q13243 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:Q13247 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:Q08170 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580700|imex:IM-25069-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:Fig. 5A|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/02/15 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rigid:fxucDBpUOl08dbT5oI5oQtRZ4ag false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:Q16629 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:Q07955 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:Q01130 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:P84103 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-372557|uniprotkb:P23152|uniprotkb:O08831|uniprotkb:B4E241|intact:EBI-11020748|uniprotkb:Q5R3K0|ensembl:ENSP00000362820|ensembl:ENSP00000482833 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:SRSF3(gene name)|psi-mi:SRSF3(display_short)|uniprotkb:SRP20(gene name synonym)|uniprotkb:SFRS3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) refseq:NP_003008.1|ensembl:ENSG00000112081(gene)|ensembl:ENST00000373715(transcript)|ensembl:ENST00000620941(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84103|rcsb pdb:2I2Y|rcsb pdb:2I38|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-32961N go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU9606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:Q13243 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:Q13247 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-2 uniprotkb:Q08170 intact:EBI-11580607|ensembl:ENSP00000424647 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:q96s94-2(display_long)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name)|uniprotkb:CCNL2s(isoform synonym) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0096"(pull down) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580725|imex:IM-25069-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000488340(transcript) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) isoform-comment:"Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT." - figure legend:Fig. 5Ai|comment:The p110 isoform of CDK11 was also observed in the complex but could not be mapped to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/15 2016/07/12 rogid:/s1QAKK808HPPHE8y4s9pQqts3o9606 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rigid:BQJ4AbTpwZUFaqmhaQ4jm1HUog4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UK58-1 uniprotkb:P68400 intact:EBI-11580567|ensembl:ENSP00000295926 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:q9uk58-1(display_long)|uniprotkb:cyclin L1alpha(isoform synonym)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)|uniprotkb:Cyclin L alpha(isoform synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660975|imex:IM-25069-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2836773(isoform-parent)|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Fig 3A|comment:CDK11-p110 also present in the complex but the exact gene product could not be determined.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/03/21 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:z77Kwo0buMVZEHNWatCIgfwZKyk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96S94-1 uniprotkb:P68400 intact:EBI-11580593|ensembl:ENSP00000383611 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:q96s94-1(display_long)|uniprotkb:cyclin L2alpha(isoform synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:SB138(orf name) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Loyer et al. (2008) imex:IM-25069|pubmed:18216018 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11660979|imex:IM-25069-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1045974(isoform-parent)|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Fig 3A,|comment:CDK11-p110 also present in the complex but the exact gene product could not be determined|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/15 2016/03/21 rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:rZ04qj9bQdpcV5fDLTaiEgXpDWw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)