#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:60568" uniprotkb:P12259-PRO_0000002981 intact:EBI-11700201 intact:EBI-11700221 psi-mi:1,2-dioleoyl-sn-glycero-3-phospho-l-serine(display_short)|psi-mi:"CHEBI:60568"(display_long)|intact:1,2-Dioleoyl-sn-glycero-3-phosphoserine(synonym)|intact:1,2-Dioleoylphosphatidylserine(synonym)|intact:1,2-Dlps(synonym)|intact:Dioleoyl phosphatidylserine(synonym)|intact:DOPS(synonym)|intact:DOPSE(synonym)|intact:"Phosphatidylserine(18:1/18:1)"(synonym)|intact:"Phosphatidylserine(18:1omega9/18:1omega9)"(synonym)|intact:"Phosphatidylserine(36:2)"(synonym)|intact:"PS(18:1(9Z)/18:1(9Z))"(synonym)|intact:"PS(18:1/18:1)"(synonym)|intact:"PS(18:1omega9/18:1omega9)"(synonym)|intact:"PS(36:2)"(synonym)|intact:"O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine"(iupac name) psi-mi:p12259-pro_0000002981(display_long)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym)|uniprotkb:F5(gene name)|psi-mi:F5(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11700199|imex:IM-25246-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-9640912(chain-parent) - - chain-seq-start:1574|chain-seq-end:2224 figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/05/12 - rogid:pVQSTESA97xniM3Kpk8ELOcPiCU9606 - false - sufficient binding region:1-651 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:60568" uniprotkb:P12259-PRO_0000002979 intact:EBI-11700201 intact:EBI-11700226 psi-mi:1,2-dioleoyl-sn-glycero-3-phospho-l-serine(display_short)|psi-mi:"CHEBI:60568"(display_long)|intact:1,2-Dioleoyl-sn-glycero-3-phosphoserine(synonym)|intact:1,2-Dioleoylphosphatidylserine(synonym)|intact:1,2-Dlps(synonym)|intact:Dioleoyl phosphatidylserine(synonym)|intact:DOPS(synonym)|intact:DOPSE(synonym)|intact:"Phosphatidylserine(18:1/18:1)"(synonym)|intact:"Phosphatidylserine(18:1omega9/18:1omega9)"(synonym)|intact:"Phosphatidylserine(36:2)"(synonym)|intact:"PS(18:1(9Z)/18:1(9Z))"(synonym)|intact:"PS(18:1/18:1)"(synonym)|intact:"PS(18:1omega9/18:1omega9)"(synonym)|intact:"PS(36:2)"(synonym)|intact:"O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine"(iupac name) psi-mi:p12259-pro_0000002979(display_long)|uniprotkb:F5(gene name)|psi-mi:F5(display_short)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11700199|imex:IM-25246-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-9640912(chain-parent)|uniprotkb:P12259(chain-parent) - - chain-seq-start:29|chain-seq-end:737 figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/05/12 - rogid:ZkDcmGzFvG0Jy1ys7bCFVPB+T+U9606 - false - sufficient binding region:1-709 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:60568" chebi:"CHEBI:74669" intact:EBI-11700201 intact:EBI-11700255 psi-mi:1,2-dioleoyl-sn-glycero-3-phospho-l-serine(display_short)|psi-mi:"CHEBI:60568"(display_long)|intact:1,2-Dioleoyl-sn-glycero-3-phosphoserine(synonym)|intact:1,2-Dioleoylphosphatidylserine(synonym)|intact:1,2-Dlps(synonym)|intact:Dioleoyl phosphatidylserine(synonym)|intact:DOPS(synonym)|intact:DOPSE(synonym)|intact:"Phosphatidylserine(18:1/18:1)"(synonym)|intact:"Phosphatidylserine(18:1omega9/18:1omega9)"(synonym)|intact:"Phosphatidylserine(36:2)"(synonym)|intact:"PS(18:1(9Z)/18:1(9Z))"(synonym)|intact:"PS(18:1/18:1)"(synonym)|intact:"PS(18:1omega9/18:1omega9)"(synonym)|intact:"PS(36:2)"(synonym)|intact:"O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine"(iupac name) psi-mi:1,2-dioleoyl-sn-glycero-3-phosphocholine(display_short)|psi-mi:"CHEBI:74669"(display_long)|intact:"(R-(Z,Z))-(7-Oleoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-enyl)trimethylammonium 4-oxide"(synonym)|intact:"1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine"(synonym)|intact:"1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine"(synonym)|intact:1,2-dioleoyl-L-alpha-lecithin(synonym)|intact:"1-(9Z)-octadecenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine"(synonym)|intact:"1-C18:1(omega-9)-2-C18:1(omega-9)-phosphatidylcholine"(synonym)|intact:Dioleoyl lecithin(synonym)|intact:Dioleoyl phosphatidylcholine(synonym)|intact:"PC(18:1(9Z)/18:1(9Z))"(synonym)|intact:"PC(18:1/18:1)"(synonym)|intact:"(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylazaniumyl)ethyl phosphate"(iupac name) psi-mi:"MI:1211"(liposome binding assay) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700246|imex:IM-25246-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/05/12 - - - false - - 1 3 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:60568" uniprotkb:P12259-PRO_0000002979 intact:EBI-11700201 intact:EBI-11700226 psi-mi:1,2-dioleoyl-sn-glycero-3-phospho-l-serine(display_short)|psi-mi:"CHEBI:60568"(display_long)|intact:1,2-Dioleoyl-sn-glycero-3-phosphoserine(synonym)|intact:1,2-Dioleoylphosphatidylserine(synonym)|intact:1,2-Dlps(synonym)|intact:Dioleoyl phosphatidylserine(synonym)|intact:DOPS(synonym)|intact:DOPSE(synonym)|intact:"Phosphatidylserine(18:1/18:1)"(synonym)|intact:"Phosphatidylserine(18:1omega9/18:1omega9)"(synonym)|intact:"Phosphatidylserine(36:2)"(synonym)|intact:"PS(18:1(9Z)/18:1(9Z))"(synonym)|intact:"PS(18:1/18:1)"(synonym)|intact:"PS(18:1omega9/18:1omega9)"(synonym)|intact:"PS(36:2)"(synonym)|intact:"O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine"(iupac name) psi-mi:p12259-pro_0000002979(display_long)|uniprotkb:F5(gene name)|psi-mi:F5(display_short)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym) psi-mi:"MI:1211"(liposome binding assay) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700246|imex:IM-25246-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-9640912(chain-parent)|uniprotkb:P12259(chain-parent) - - chain-seq-start:29|chain-seq-end:737 figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/05/12 - rogid:ZkDcmGzFvG0Jy1ys7bCFVPB+T+U9606 - false - sufficient binding region:1-709 1 - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:60568" uniprotkb:P12259-PRO_0000002981 intact:EBI-11700201 intact:EBI-11700221 psi-mi:1,2-dioleoyl-sn-glycero-3-phospho-l-serine(display_short)|psi-mi:"CHEBI:60568"(display_long)|intact:1,2-Dioleoyl-sn-glycero-3-phosphoserine(synonym)|intact:1,2-Dioleoylphosphatidylserine(synonym)|intact:1,2-Dlps(synonym)|intact:Dioleoyl phosphatidylserine(synonym)|intact:DOPS(synonym)|intact:DOPSE(synonym)|intact:"Phosphatidylserine(18:1/18:1)"(synonym)|intact:"Phosphatidylserine(18:1omega9/18:1omega9)"(synonym)|intact:"Phosphatidylserine(36:2)"(synonym)|intact:"PS(18:1(9Z)/18:1(9Z))"(synonym)|intact:"PS(18:1/18:1)"(synonym)|intact:"PS(18:1omega9/18:1omega9)"(synonym)|intact:"PS(36:2)"(synonym)|intact:"O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine"(iupac name) psi-mi:p12259-pro_0000002981(display_long)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym)|uniprotkb:F5(gene name)|psi-mi:F5(display_short) psi-mi:"MI:1211"(liposome binding assay) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700246|imex:IM-25246-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-9640912(chain-parent) - - chain-seq-start:1574|chain-seq-end:2224 figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/05/12 - rogid:pVQSTESA97xniM3Kpk8ELOcPiCU9606 - false - sufficient binding region:1-651 1 - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15537 uniprotkb:P14415 intact:EBI-11700281|uniprotkb:Q0QD39|ensembl:ENSP00000369320 intact:EBI-11700309|uniprotkb:A0AV17|uniprotkb:A8K278|uniprotkb:D3DTQ2|uniprotkb:O60444|ensembl:ENSP00000250111 psi-mi:xlrs1_human(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short)|uniprotkb:XLRS1(gene name synonym)|uniprotkb:X-linked juvenile retinoschisis protein(gene name synonym) psi-mi:at1b2_human(display_long)|uniprotkb:ATP1B2(gene name)|psi-mi:ATP1B2(display_short)|uniprotkb:Adhesion molecule in glia(gene name synonym)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700279|imex:IM-25246-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000321.1|ensembl:ENSG00000102104(gene)|ensembl:ENST00000379984(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007601"(visual perception)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:3JD6|rcsb pdb:5N6W refseq:NP_001290192.1|refseq:NP_001669.3|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|ensembl:ENSG00000129244(gene)|ensembl:ENST00000250111(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021944"(neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0044298"(cell body membrane)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061744"(motor behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0120036"(plasma membrane bounded cell projection organization)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-retina)|taxid:9606(Human retina cells) - 2016/05/05 2016/05/12 rogid:h0XS4i9qFIikLeSGL9hNzQklXMw9606 rogid:O3Hqh2qqpwG+z/k/DU3/Ca4aZ7g9606 rigid:0TA2sIDUUT5AffBroElWYumgEwk false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15537 uniprotkb:Q6SZW1 intact:EBI-11700281|uniprotkb:Q0QD39|ensembl:ENSP00000369320 intact:EBI-11693532|uniprotkb:O60277|uniprotkb:Q7LGG3|uniprotkb:Q9NXY5|ensembl:ENSP00000468032 psi-mi:xlrs1_human(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short)|uniprotkb:XLRS1(gene name synonym)|uniprotkb:X-linked juvenile retinoschisis protein(gene name synonym) psi-mi:sarm1_human(display_long)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700279|imex:IM-25246-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000321.1|ensembl:ENSG00000102104(gene)|ensembl:ENST00000379984(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007601"(visual perception)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:3JD6|rcsb pdb:5N6W refseq:NP_055892.2|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript)|go:"GO:0003953"(NAD+ nucleosidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0009749"(response to glucose)|go:"GO:0019677"(NAD catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048678"(response to axon injury)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035897|interpro:IPR039184|rcsb pdb:6O0Q|rcsb pdb:6O0R|rcsb pdb:6O0S|rcsb pdb:6O0T|rcsb pdb:6O0U|rcsb pdb:6O0V|rcsb pdb:6O1B|rcsb pdb:6QWV|rcsb pdb:6WPK|rcsb pdb:6ZFX|rcsb pdb:6ZG0|rcsb pdb:6ZG1|rcsb pdb:7ANW|rcsb pdb:7CM5|rcsb pdb:7CM6|rcsb pdb:7CM7|rcsb pdb:7DJT|rcsb pdb:7LD0|reactome:R-HSA-166166|reactome:R-HSA-168164|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-retina)|taxid:9606(Human retina cells) - 2016/05/05 2016/05/12 rogid:h0XS4i9qFIikLeSGL9hNzQklXMw9606 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rigid:0TA2sIDUUT5AffBroElWYumgEwk false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15537 uniprotkb:P13637 intact:EBI-11700281|uniprotkb:Q0QD39|ensembl:ENSP00000369320 intact:EBI-948169|uniprotkb:Q16732|uniprotkb:Q16735|uniprotkb:Q969K5|ensembl:ENSP00000498113|uniprotkb:B7Z2T0|uniprotkb:B7Z401|uniprotkb:F5H6J6 psi-mi:xlrs1_human(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short)|uniprotkb:XLRS1(gene name synonym)|uniprotkb:X-linked juvenile retinoschisis protein(gene name synonym) psi-mi:at1a3_human(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:ATP1A3(gene name)|psi-mi:ATP1A3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700279|imex:IM-25246-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000321.1|ensembl:ENSG00000102104(gene)|ensembl:ENST00000379984(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007601"(visual perception)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:3JD6|rcsb pdb:5N6W refseq:NP_689509.1|ensembl:ENSG00000105409(gene)|ensembl:ENST00000648268(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P13637|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_001243142.1|refseq:NP_001243143.1 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-retina)|taxid:9606(Human retina cells) - 2016/05/05 2016/05/12 rogid:h0XS4i9qFIikLeSGL9hNzQklXMw9606 rogid:iDlxP7yaZPX85GQKmHOe0KvnS2w9606 rigid:0TA2sIDUUT5AffBroElWYumgEwk false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1MPS1 uniprotkb:F1MR06 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11703757|ensembl:ENSBTAP00000024797 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:f1mr06_bovin(display_long)|uniprotkb:ATP1A3(gene name)|psi-mi:ATP1A3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700474|imex:IM-25246-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) ensembl:ENSBTAG00000018635(gene)|ensembl:ENSBTAT00000024797(transcript)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:UXVpLC9IB2H5geM0EuSlWtx+Xzo9913 rigid:KsuB5Ej6JbCJHNMkquYvvW2ozco false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MPS1 uniprotkb:Q28030 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11700481 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:at1b2_bovin(display_long)|uniprotkb:ATP1B2(gene name)|psi-mi:ATP1B2(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700474|imex:IM-25246-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) refseq:NP_777102.1|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR038702 - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:0lK7CUMhdxDKTGZX6QuFr06sbVU9913 rigid:KsuB5Ej6JbCJHNMkquYvvW2ozco false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MPS1 uniprotkb:E1BIR9 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11703492|ensembl:ENSBTAP00000003645 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:e1bir9_bovin(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700474|imex:IM-25246-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) ensembl:ENSBTAG00000002816(gene)|ensembl:ENSBTAT00000003645(transcript)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0019677"(NAD catabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048678"(response to axon injury)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035897|interpro:IPR039184 - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:s8arGeqVySjU/Z4XTdnHhV1FcRk9913 rigid:KsuB5Ej6JbCJHNMkquYvvW2ozco false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MPS1 uniprotkb:F1MR06 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11703757|ensembl:ENSBTAP00000024797 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:f1mr06_bovin(display_long)|uniprotkb:ATP1A3(gene name)|psi-mi:ATP1A3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700493|imex:IM-25246-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) ensembl:ENSBTAG00000018635(gene)|ensembl:ENSBTAT00000024797(transcript)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 - - - figure legend:4i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:UXVpLC9IB2H5geM0EuSlWtx+Xzo9913 rigid:nrCQx9glqzgpX0QAesqRp7PeNGA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MPS1 uniprotkb:E1BIR9 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11703492|ensembl:ENSBTAP00000003645 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:e1bir9_bovin(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700493|imex:IM-25246-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) ensembl:ENSBTAG00000002816(gene)|ensembl:ENSBTAT00000003645(transcript)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0019677"(NAD catabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048678"(response to axon injury)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035897|interpro:IPR039184 - - - figure legend:4i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:s8arGeqVySjU/Z4XTdnHhV1FcRk9913 rigid:nrCQx9glqzgpX0QAesqRp7PeNGA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MPS1 uniprotkb:Q28030 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11700481 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:at1b2_bovin(display_long)|uniprotkb:ATP1B2(gene name)|psi-mi:ATP1B2(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700493|imex:IM-25246-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) refseq:NP_777102.1|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR038702 - - - figure legend:4i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:0lK7CUMhdxDKTGZX6QuFr06sbVU9913 rigid:nrCQx9glqzgpX0QAesqRp7PeNGA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1MPS1 uniprotkb:O15537 intact:EBI-11700473|ensembl:ENSBTAP00000041587 intact:EBI-11700281|uniprotkb:Q0QD39|ensembl:ENSP00000369320 psi-mi:f1mps1_bovin(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short) psi-mi:xlrs1_human(display_long)|uniprotkb:RS1(gene name)|psi-mi:RS1(display_short)|uniprotkb:XLRS1(gene name synonym)|uniprotkb:X-linked juvenile retinoschisis protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700493|imex:IM-25246-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000031145(gene)|ensembl:ENSBTAT00000044074(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) refseq:NP_000321.1|ensembl:ENSG00000102104(gene)|ensembl:ENST00000379984(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007601"(visual perception)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:3JD6|rcsb pdb:5N6W - - - figure legend:4i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/05/05 2019/04/15 rogid:2m1WhT2AzFkMSsEeawgZHshM31c9913 rogid:h0XS4i9qFIikLeSGL9hNzQklXMw9606 rigid:nrCQx9glqzgpX0QAesqRp7PeNGA false - sufficient binding region:22-37 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6PIC6 uniprotkb:Q9Z1L4 intact:EBI-769101|ensembl:ENSMUSP00000079691 intact:EBI-11700511|ensembl:ENSMUSP00000033650 psi-mi:at1a3_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short) psi-mi:xlrs1_mouse(display_long)|uniprotkb:Rs1(gene name)|psi-mi:Rs1(display_short)|uniprotkb:Rs1h(gene name synonym)|uniprotkb:Xlrs1(gene name synonym)|uniprotkb:X-linked juvenile retinoschisis protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11700509|imex:IM-25246-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277398.1|ensembl:ENSMUSG00000040907(gene)|ensembl:ENSMUST00000080882(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|reactome:R-MMU-936837|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIC6|go:"GO:0045202"(synapse)|reactome:R-MMU-5578775 refseq:NP_035432.3|ensembl:ENSMUSG00000031293(gene)|ensembl:ENSMUST00000033650(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) - - - figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2016/05/05 2016/05/13 rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10090 rogid:66QFoRqVv9FccauBYSLDmMyHsgQ10090 rigid:U269SBFOI1rthdMBuFMe7rMZcqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6PIC6 uniprotkb:Q9Z1L4 intact:EBI-769101|ensembl:ENSMUSP00000079691 intact:EBI-11700511|ensembl:ENSMUSP00000033650 psi-mi:at1a3_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short) psi-mi:xlrs1_mouse(display_long)|uniprotkb:Rs1(gene name)|psi-mi:Rs1(display_short)|uniprotkb:Rs1h(gene name synonym)|uniprotkb:Xlrs1(gene name synonym)|uniprotkb:X-linked juvenile retinoschisis protein homolog(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11700545|imex:IM-25246-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277398.1|ensembl:ENSMUSG00000040907(gene)|ensembl:ENSMUST00000080882(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|reactome:R-MMU-936837|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIC6|go:"GO:0045202"(synapse)|reactome:R-MMU-5578775 refseq:NP_035432.3|ensembl:ENSMUSG00000031293(gene)|ensembl:ENSMUST00000033650(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098984"(neuron to neuron synapse)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like) - - - figure legend:6 C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2016/05/05 2016/05/13 rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10090 rogid:66QFoRqVv9FccauBYSLDmMyHsgQ10090 rigid:U269SBFOI1rthdMBuFMe7rMZcqs false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q6PIC6 uniprotkb:Q6PDS3 intact:EBI-769101|ensembl:ENSMUSP00000079691 intact:EBI-6117196|uniprotkb:Q5SYG5|uniprotkb:Q5SYG6|uniprotkb:Q6A054|uniprotkb:Q6SZW0|uniprotkb:Q8BRI9|ensembl:ENSMUSP00000051059 psi-mi:at1a3_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short) psi-mi:sarm1_mouse(display_long)|uniprotkb:Sarm1(gene name)|psi-mi:Sarm1(display_short)|uniprotkb:Kiaa0524(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Molday et al. (2007) imex:IM-25246|pubmed:17804407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11700549|imex:IM-25246-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277398.1|ensembl:ENSMUSG00000040907(gene)|ensembl:ENSMUST00000080882(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|reactome:R-MMU-936837|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIC6|go:"GO:0045202"(synapse)|reactome:R-MMU-5578775 refseq:NP_001161993.1|refseq:NP_766383.2|ensembl:ENSMUSG00000050132(gene)|ensembl:ENSMUST00000061174(transcript)|go:"GO:0003953"(NAD+ nucleosidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0009749"(response to glucose)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019677"(NAD catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048678"(response to axon injury)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035897|interpro:IPR039184|reactome:R-MMU-166166|reactome:R-MMU-936964|reactome:R-MMU-937041|reactome:R-MMU-937072 - - - figure legend:6 F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2016/05/05 2016/05/13 rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10090 rogid:tIi/ujPHqfCjECm37VY+KKMx0Xk10090 rigid:OeG9C3vUBkAN4pfrAsmT6E4kKuQ false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)