#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H444 uniprotkb:Q8WUX9 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 intact:EBI-749253|uniprotkb:Q8NDM1|uniprotkb:Q9BT50|uniprotkb:B2RDT3|uniprotkb:D3DSS1|uniprotkb:B4DKJ6|ensembl:ENSP00000324491|ensembl:ENSP00000380794 psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:chmp7_human(display_long)|uniprotkb:Chromatin-modifying protein 7(gene name synonym)|uniprotkb:CHMP7(gene name)|psi-mi:CHMP7(display_short) psi-mi:"MI:0096"(pull down) Horii et al. (2006) pubmed:16856878|imex:IM-24993 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11513083|imex:IM-24993-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) refseq:NP_689485.1|ensembl:ENSG00000147457(gene)|ensembl:ENST00000313219(transcript)|ensembl:ENST00000397677(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061952"(midbody abscission)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676 - - - figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/01 2016/02/01 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rogid:uRwNEK39dkdJ3zuqKck83TpoCXI9606 rigid:vqleluzymuuNgpT1W/pbY52XKrs false flag tag:n-n strep ii tag:n-n|sufficient binding region:223-453 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BRG1 uniprotkb:Q96FZ7 intact:EBI-741945|uniprotkb:B2R581|ensembl:ENSP00000253794 intact:EBI-1049648|uniprotkb:Q53FU4|uniprotkb:Q9HAE8|uniprotkb:A8K7U0|ensembl:ENSP00000317468 psi-mi:vps25_human(display_long)|uniprotkb:ELL-associated protein of 20 kDa(gene name synonym)|uniprotkb:Dermal papilla-derived protein 9(gene name synonym)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:DERP9(gene name synonym)|uniprotkb:EAP20(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym) psi-mi:chmp6_human(display_long)|uniprotkb:Chromatin-modifying protein 6(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 20(gene name synonym)|uniprotkb:CHMP6(gene name)|psi-mi:CHMP6(display_short)|uniprotkb:VPS20(gene name synonym) psi-mi:"MI:0096"(pull down) Horii et al. (2006) pubmed:16856878|imex:IM-24993 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11513095|imex:IM-24993-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000253794(transcript)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131475(gene)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2ZME|rcsb pdb:3CUQ|rcsb pdb:3HTU|reactome:R-HSA-917729|reactome:R-HSA-9610379|refseq:NP_115729.1 refseq:NP_078867.2|ensembl:ENSG00000176108(gene)|ensembl:ENST00000325167(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|mint:Q96FZ7|rcsb pdb:2K3W|rcsb pdb:3HTU|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0016020"(membrane) - - - figure legend:Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/02/01 2016/02/01 rogid:fAf3o5rwpM1xz53oIyMwohQfbEg9606 rogid:UR/trNCJYky7bD9sxvSnCz0FGkg9606 rigid:I6o357LxTtz/WIBSAMbHj9Hwb/A false flag tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BY43 uniprotkb:Q8WUX9 intact:EBI-747981|uniprotkb:Q32Q79|uniprotkb:Q86SZ8|uniprotkb:Q96QJ9|uniprotkb:Q9P026|uniprotkb:Q14D22|intact:EBI-11150912|ensembl:ENSP00000324205|ensembl:ENSP00000495982 intact:EBI-749253|uniprotkb:Q8NDM1|uniprotkb:Q9BT50|uniprotkb:B2RDT3|uniprotkb:D3DSS1|uniprotkb:B4DKJ6|ensembl:ENSP00000324491|ensembl:ENSP00000380794 psi-mi:chm4a_human(display_long)|uniprotkb:Chromatin-modifying protein 4a(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-1(gene name synonym)|uniprotkb:SNF7-1(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix-2(gene name synonym)|uniprotkb:CHMP4A(gene name)|psi-mi:CHMP4A(display_short)|uniprotkb:C14orf123(gene name synonym)|uniprotkb:SHAX2(gene name synonym)|uniprotkb:CDA04(orf name)|uniprotkb:HSPC134(orf name) psi-mi:chmp7_human(display_long)|uniprotkb:Chromatin-modifying protein 7(gene name synonym)|uniprotkb:CHMP7(gene name)|psi-mi:CHMP7(display_short) psi-mi:"MI:0018"(two hybrid) Horii et al. (2006) pubmed:16856878|imex:IM-24993 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11513112|imex:IM-24993-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054888.2|ensembl:ENSG00000254505(gene)|ensembl:ENSG00000285302(gene)|ensembl:ENST00000347519(transcript)|ensembl:ENST00000645308(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008289"(lipid binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010324"(membrane invagination)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9BY43|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|rcsb pdb:3C3O|rcsb pdb:5MK1|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-39082N refseq:NP_689485.1|ensembl:ENSG00000147457(gene)|ensembl:ENST00000313219(transcript)|ensembl:ENST00000397677(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061952"(midbody abscission)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676 - - - figure legend:text only|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/02/01 2016/02/01 rogid:37u80uKlCjnNuiXMSgos22rP0Ek9606 rogid:uRwNEK39dkdJ3zuqKck83TpoCXI9606 rigid:mHxyDR09Okiat1vAIQd4eUFVnAM false gal4 activation domain:n-n sufficient binding region:223-453|gal4 dna binding domain:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H444 uniprotkb:Q8WUX9 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 intact:EBI-749253|uniprotkb:Q8NDM1|uniprotkb:Q9BT50|uniprotkb:B2RDT3|uniprotkb:D3DSS1|uniprotkb:B4DKJ6|ensembl:ENSP00000324491|ensembl:ENSP00000380794 psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:chmp7_human(display_long)|uniprotkb:Chromatin-modifying protein 7(gene name synonym)|uniprotkb:CHMP7(gene name)|psi-mi:CHMP7(display_short) psi-mi:"MI:0018"(two hybrid) Horii et al. (2006) pubmed:16856878|imex:IM-24993 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11513124|imex:IM-24993-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) refseq:NP_689485.1|ensembl:ENSG00000147457(gene)|ensembl:ENST00000313219(transcript)|ensembl:ENST00000397677(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061952"(midbody abscission)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676 - - - figure legend:text only|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/02/01 2016/02/01 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rogid:uRwNEK39dkdJ3zuqKck83TpoCXI9606 rigid:vqleluzymuuNgpT1W/pbY52XKrs false gal4 activation domain:n-n sufficient binding region:223-453|gal4 dna binding domain:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CF2 uniprotkb:Q8WUX9 intact:EBI-1221015|uniprotkb:B2RBZ1|ensembl:ENSP00000297265 intact:EBI-749253|uniprotkb:Q8NDM1|uniprotkb:Q9BT50|uniprotkb:B2RDT3|uniprotkb:D3DSS1|uniprotkb:B4DKJ6|ensembl:ENSP00000324491|ensembl:ENSP00000380794 psi-mi:chm4c_human(display_long)|uniprotkb:CHMP4C(gene name)|psi-mi:CHMP4C(display_short)|uniprotkb:SHAX3(gene name synonym)|uniprotkb:Chromatin-modifying protein 4c(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-3(gene name synonym)|uniprotkb:SNF7-3(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 3(gene name synonym) psi-mi:chmp7_human(display_long)|uniprotkb:Chromatin-modifying protein 7(gene name synonym)|uniprotkb:CHMP7(gene name)|psi-mi:CHMP7(display_short) psi-mi:"MI:0018"(two hybrid) Horii et al. (2006) pubmed:16856878|imex:IM-24993 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11513134|imex:IM-24993-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689497.1|dip:DIP-38342N|ensembl:ENSG00000164695(gene)|ensembl:ENST00000297265(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009838"(abscission)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR005024(Snf7)|mint:Q96CF2|rcsb pdb:3C3R|rcsb pdb:5MK3|rcsb pdb:5V3R|rcsb pdb:5WA1|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676 refseq:NP_689485.1|ensembl:ENSG00000147457(gene)|ensembl:ENST00000313219(transcript)|ensembl:ENST00000397677(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061952"(midbody abscission)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676 - - - figure legend:text only|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/02/01 2016/02/01 rogid:LOB+DG//5OsYsyKDaziJYV2fxFo9606 rogid:uRwNEK39dkdJ3zuqKck83TpoCXI9606 rigid:i9TgVJSZzSTkgv9trlfD0EiF+iQ false gal4 activation domain:n-n sufficient binding region:223-453|gal4 dna binding domain:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WUX9 uniprotkb:Q9H444 intact:EBI-749253|uniprotkb:Q8NDM1|uniprotkb:Q9BT50|uniprotkb:B2RDT3|uniprotkb:D3DSS1|uniprotkb:B4DKJ6|ensembl:ENSP00000324491|ensembl:ENSP00000380794 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 psi-mi:chmp7_human(display_long)|uniprotkb:Chromatin-modifying protein 7(gene name synonym)|uniprotkb:CHMP7(gene name)|psi-mi:CHMP7(display_short) psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Horii et al. (2006) pubmed:16856878|imex:IM-24993 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11513154|imex:IM-24993-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689485.1|ensembl:ENSG00000147457(gene)|ensembl:ENST00000313219(transcript)|ensembl:ENST00000397677(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010458"(exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061952"(midbody abscission)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676 refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) - - - figure legend:Fig. 3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/02/01 2016/02/01 rogid:uRwNEK39dkdJ3zuqKck83TpoCXI9606 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rigid:vqleluzymuuNgpT1W/pbY52XKrs false flag tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:1199"(anti-tag immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry)