#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09326 uniprotkb:Q9BZW8 intact:EBI-714770|uniprotkb:Q5U055|ensembl:ENSP00000357025|uniprotkb:Q8MGR0 intact:EBI-1580565|uniprotkb:Q96T47|uniprotkb:Q9NQD2|uniprotkb:Q9NQD3|uniprotkb:Q9Y288|uniprotkb:Q5VYI2|uniprotkb:Q5VYI6|uniprotkb:Q5VYI7|ensembl:ENSP00000357012 psi-mi:cd48_human(display_long)|uniprotkb:B-lymphocyte activation marker BLAST-1(gene name synonym)|uniprotkb:BCM1 surface antigen(gene name synonym)|uniprotkb:Leukocyte antigen MEM-102(gene name synonym)|uniprotkb:TCT.1(gene name synonym)|uniprotkb:CD48(gene name)|psi-mi:CD48(display_short)|uniprotkb:BCM1(gene name synonym)|uniprotkb:BLAST1(gene name synonym)|uniprotkb:SLAM family member 2(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 2(gene name synonym) psi-mi:cd244_human(display_long)|uniprotkb:NK cell type I receptor protein 2B4(gene name synonym)|uniprotkb:NK cell activation-inducing ligand(gene name synonym)|uniprotkb:CD244(gene name)|psi-mi:CD244(display_short)|uniprotkb:2B4(gene name synonym)|uniprotkb:SLAM family member 4(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 4(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Mathew et al. (2005) imex:IM-24983|pubmed:16002700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11477139|imex:IM-24983-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117091(gene)|ensembl:ENST00000368046(transcript)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033548|interpro:IPR036179|rcsb pdb:2EDO|reactome:R-HSA-202733|refseq:NP_001769.2 refseq:XP_011507924.1|refseq:NP_001160135.1|refseq:NP_001160136.1|refseq:NP_057466.1|dip:DIP-40331N|ensembl:ENSG00000122223(gene)|ensembl:ENST00000368033(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002323"(natural killer cell activation involved in immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0060732"(positive regulation of inositol phosphate biosynthetic process)|go:"GO:0071663"(positive regulation of granzyme B production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR024303|interpro:IPR024304|interpro:IPR036179|reactome:R-HSA-202733 - - - figure legend:1B, 4, Table II|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/01/13 2016/01/13 rogid:IFn8oYvbQHpUpnEYAd1ss/ZfUe89606 rogid:QORMx+ZJyNjvraEeZH1rBgcD2bU9606 rigid:miNZ4EuaJj1K5fp1ZEl3Ht6M4W0 false sufficient binding region:27..27-220..220|fc-igg tag:c-c mutation decreasing interaction:70-70|mutation disrupting interaction:68-68,70-70|mutation decreasing interaction:68-68 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P09326 uniprotkb:P09326 intact:EBI-714770|uniprotkb:Q5U055|ensembl:ENSP00000357025|uniprotkb:Q8MGR0 intact:EBI-714770|uniprotkb:Q5U055|ensembl:ENSP00000357025|uniprotkb:Q8MGR0 psi-mi:cd48_human(display_long)|uniprotkb:B-lymphocyte activation marker BLAST-1(gene name synonym)|uniprotkb:BCM1 surface antigen(gene name synonym)|uniprotkb:Leukocyte antigen MEM-102(gene name synonym)|uniprotkb:TCT.1(gene name synonym)|uniprotkb:CD48(gene name)|psi-mi:CD48(display_short)|uniprotkb:BCM1(gene name synonym)|uniprotkb:BLAST1(gene name synonym)|uniprotkb:SLAM family member 2(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 2(gene name synonym) psi-mi:cd48_human(display_long)|uniprotkb:B-lymphocyte activation marker BLAST-1(gene name synonym)|uniprotkb:BCM1 surface antigen(gene name synonym)|uniprotkb:Leukocyte antigen MEM-102(gene name synonym)|uniprotkb:TCT.1(gene name synonym)|uniprotkb:CD48(gene name)|psi-mi:CD48(display_short)|uniprotkb:BCM1(gene name synonym)|uniprotkb:BLAST1(gene name synonym)|uniprotkb:SLAM family member 2(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 2(gene name synonym) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Mathew et al. (2005) imex:IM-24983|pubmed:16002700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11477160|imex:IM-24983-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117091(gene)|ensembl:ENST00000368046(transcript)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033548|interpro:IPR036179|rcsb pdb:2EDO|reactome:R-HSA-202733|refseq:NP_001769.2 ensembl:ENSG00000117091(gene)|ensembl:ENST00000368046(transcript)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033548|interpro:IPR036179|rcsb pdb:2EDO|reactome:R-HSA-202733|refseq:NP_001769.2 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2016/01/13 2016/01/15 rogid:IFn8oYvbQHpUpnEYAd1ss/ZfUe89606 rogid:IFn8oYvbQHpUpnEYAd1ss/ZfUe89606 rigid:Sx30NaDQpOnECsISRzJTuZ7AVXM false sufficient binding region:27..27-220..220|fc-igg tag:c-c sufficient binding region:27..27-220..220|fc-igg tag:c-c - 0 psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)