#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P18870 uniprotkb:Q9DGW5 intact:EBI-445826 intact:EBI-10889526 psi-mi:jun_chick(display_long)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11601208|imex:IM-26086-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026460.1|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR015558(c-Jun Transcription Factor)|reactome:R-GGA-437986|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051726"(regulation of cell cycle) refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/02/19 rogid:ERH5BayVmoT1wM8Sv1p00AJ3Nvc9031 rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 rigid:Xf0h9sXJn5VG1OH1NoiTWON2ivU false 35s radiolabel:?-? 35s radiolabel:?-?|sufficient binding region:1-127|t7 tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P09450 uniprotkb:Q9DGW5 intact:EBI-5347760|uniprotkb:Q8C2G9|ensembl:ENSMUSP00000064680 intact:EBI-10889526 psi-mi:junb_mouse(display_long)|uniprotkb:Junb(gene name)|psi-mi:Junb(display_short)|uniprotkb:Jun-b(gene name synonym)|uniprotkb:MyD21(gene name synonym) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11601218|imex:IM-26086-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1069N|refseq:NP_032442.1|ensembl:ENSMUSG00000052837(gene)|ensembl:ENSMUST00000064922(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009987"(cellular process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822 refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/02/19 rogid:jnlW1k7KFty2J0v0PVptgt0oWVo10090 rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 rigid:SHfRFgxdByDy9397Bg1UFZ57lLo false 35s radiolabel:?-? 35s radiolabel:?-?|sufficient binding region:1-127|t7 tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619724 uniprotkb:Q9DGW5 - intact:EBI-10889526 psi-mi:mdv-ori(display_short)|psi-mi:EBI-11619724(display_long) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10390(Gallid herpesvirus 2)|taxid:10390(Gallid herpesvirus 2) taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619722|imex:IM-26086-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619724 uniprotkb:Q9DGW5 - intact:EBI-10889526 psi-mi:mdv-ori(display_short)|psi-mi:EBI-11619724(display_long) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10390(Gallid herpesvirus 2)|taxid:10390(Gallid herpesvirus 2) taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619722|imex:IM-26086-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619737 uniprotkb:P17325 - intact:EBI-7709365|ensembl:ENSRNOP00000011732|intact:MINT-220059 psi-mi:cre(display_short)|psi-mi:EBI-11619737(display_long) psi-mi:jun_rat(display_long)|uniprotkb:Jun(gene name)|psi-mi:Jun(display_short)|uniprotkb:Rjg-9(gene name synonym)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619731|imex:IM-26086-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|ensembl:ENSRNOG00000026293(gene)|ensembl:ENSRNOT00000011731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009987"(cellular process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031103"(axon regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P17325|reactome:R-RNO-2559580|reactome:R-RNO-2871796|reactome:R-RNO-450341|rgd:2943|refseq:NP_068607.1|dip:DIP-653N - - comment:mint|function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:u51ezRU+hzE0HvWZnsbAJ9sTd8s10116 - false 35s radiolabel:?-? sufficient binding region:206-315 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619737 uniprotkb:Q9DGW5 - intact:EBI-10889526 psi-mi:cre(display_short)|psi-mi:EBI-11619737(display_long) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619731|imex:IM-26086-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619742 uniprotkb:P17325 - intact:EBI-7709365|ensembl:ENSRNOP00000011732|intact:MINT-220059 psi-mi:tre(display_short)|psi-mi:EBI-11619742(display_long) psi-mi:jun_rat(display_long)|uniprotkb:Jun(gene name)|psi-mi:Jun(display_short)|uniprotkb:Rjg-9(gene name synonym)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619744|imex:IM-26086-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|ensembl:ENSRNOG00000026293(gene)|ensembl:ENSRNOT00000011731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009987"(cellular process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031103"(axon regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P17325|reactome:R-RNO-2559580|reactome:R-RNO-2871796|reactome:R-RNO-450341|rgd:2943|refseq:NP_068607.1|dip:DIP-653N - - comment:mint|function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:u51ezRU+hzE0HvWZnsbAJ9sTd8s10116 - false 35s radiolabel:?-? sufficient binding region:206-315 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619742 uniprotkb:Q9DGW5 - intact:EBI-10889526 psi-mi:tre(display_short)|psi-mi:EBI-11619742(display_long) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619744|imex:IM-26086-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619742 uniprotkb:P12841 - intact:EBI-8590661|ensembl:ENSRNOP00000010712|intact:MINT-220035|uniprotkb:Q4FDN1 psi-mi:tre(display_short)|psi-mi:EBI-11619742(display_long) psi-mi:fos_rat(display_long)|uniprotkb:Fos(gene name)|psi-mi:Fos(display_short)|uniprotkb:Cellular oncogene fos(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619753|imex:IM-26086-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSRNOT00000010712(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|mint:P12841|reactome:R-RNO-2559580|reactome:R-RNO-2871796|reactome:R-RNO-450341|ensembl:ENSRNOG00000008015(gene)|dip:DIP-6001N|rgd:2626|refseq:NP_071533.1 - - comment:mint|function:Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:Z2Uzy+YrqRF+K+uW2F98AEkHLjw10116 - false 35s radiolabel:?-? sufficient binding region:116-211 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619742 uniprotkb:Q9DGW5 - intact:EBI-10889526 psi-mi:tre(display_short)|psi-mi:EBI-11619742(display_long) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619753|imex:IM-26086-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619737 uniprotkb:P12841 - intact:EBI-8590661|ensembl:ENSRNOP00000010712|intact:MINT-220035|uniprotkb:Q4FDN1 psi-mi:cre(display_short)|psi-mi:EBI-11619737(display_long) psi-mi:fos_rat(display_long)|uniprotkb:Fos(gene name)|psi-mi:Fos(display_short)|uniprotkb:Cellular oncogene fos(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619762|imex:IM-26086-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSRNOT00000010712(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|mint:P12841|reactome:R-RNO-2559580|reactome:R-RNO-2871796|reactome:R-RNO-450341|ensembl:ENSRNOG00000008015(gene)|dip:DIP-6001N|rgd:2626|refseq:NP_071533.1 - - comment:mint|function:Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:Z2Uzy+YrqRF+K+uW2F98AEkHLjw10116 - false 35s radiolabel:?-? sufficient binding region:116-211 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-11619737 uniprotkb:Q9DGW5 - intact:EBI-10889526 psi-mi:cre(display_short)|psi-mi:EBI-11619737(display_long) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619762|imex:IM-26086-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 - rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P18870 uniprotkb:Q9DGW5 intact:EBI-445826 intact:EBI-10889526 psi-mi:jun_chick(display_long)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11601262|imex:IM-26086-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026460.1|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR015558(c-Jun Transcription Factor)|reactome:R-GGA-437986|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051726"(regulation of cell cycle) refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-msb-1)|taxid:9031(chick lymphoblastoid cell line) - 2016/02/19 2016/02/19 rogid:ERH5BayVmoT1wM8Sv1p00AJ3Nvc9031 rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 rigid:Xf0h9sXJn5VG1OH1NoiTWON2ivU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P18870 uniprotkb:Q9DGW5 intact:EBI-445826 intact:EBI-10889526 psi-mi:jun_chick(display_long)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-11601273|imex:IM-26086-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026460.1|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR015558(c-Jun Transcription Factor)|reactome:R-GGA-437986|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051726"(regulation of cell cycle) refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N go:"GO:0042025"(host cell nucleus) - - figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-msb-1)|taxid:9031(chick lymphoblastoid cell line) - 2016/02/19 2016/02/19 rogid:ERH5BayVmoT1wM8Sv1p00AJ3Nvc9031 rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 rigid:Xf0h9sXJn5VG1OH1NoiTWON2ivU false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P18870 uniprotkb:Q9DGW5 intact:EBI-445826 intact:EBI-10889526 psi-mi:jun_chick(display_long)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619624|imex:IM-26086-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026460.1|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR015558(c-Jun Transcription Factor)|reactome:R-GGA-437986|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051726"(regulation of cell cycle) refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 rogid:ERH5BayVmoT1wM8Sv1p00AJ3Nvc9031 rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 rigid:Xf0h9sXJn5VG1OH1NoiTWON2ivU false 35s radiolabel:?-? 35s radiolabel:?-?|sufficient binding region:1-127|t7 tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P09450 uniprotkb:Q9DGW5 intact:EBI-5347760|uniprotkb:Q8C2G9|ensembl:ENSMUSP00000064680 intact:EBI-10889526 psi-mi:junb_mouse(display_long)|uniprotkb:Junb(gene name)|psi-mi:Junb(display_short)|uniprotkb:Jun-b(gene name synonym)|uniprotkb:MyD21(gene name synonym) psi-mi:meq_gahvm(display_long)|uniprotkb:MDV005(gene name)|psi-mi:MDV005(display_short)|uniprotkb:MDV076(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Levy et al. (2003) pubmed:14610205|imex:IM-26086 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10389(gahvm)|taxid:10389("Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11619660|imex:IM-26086-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-1069N|refseq:NP_032442.1|ensembl:ENSMUSG00000052837(gene)|ensembl:ENSMUST00000064922(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009987"(cellular process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822 refseq:YP_001033919.1|refseq:YP_001033993.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-61102N - - - figure legend:1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/19 2016/03/07 rogid:jnlW1k7KFty2J0v0PVptgt0oWVo10090 rogid:v/ix39sBlTDyAhBykS66sNt6d1w10389 rigid:SHfRFgxdByDy9397Bg1UFZ57lLo false 35s radiolabel:?-? 35s radiolabel:?-?|sufficient binding region:1-127|t7 tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)