#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-11705578	uniprotkb:P53759	rnacentral:URS00000890D0_559292	intact:EBI-27885|uniprotkb:D6W0K3|ensemblfungi:YML080W	psi-mi:trna phe gaa  precursor(display_short)|psi-mi:EBI-11705578(display_long)	psi-mi:dus1_yeast(display_long)|uniprotkb:DUS1(gene name)|psi-mi:DUS1(display_short)|uniprotkb:tRNA-dihydrouridine synthase 1(gene name synonym)|uniprotkb:YML080W(locus name)	psi-mi:"MI:0415"(enzymatic study)	Xing et al. (2002)	pubmed:12003496|imex:IM-25496	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705541|imex:IM-25496-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_013631.1|sgd:S000004545|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|ensemblfungi:YML080W(gene)|ensemblfungi:YML080W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006400"(tRNA modification)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102263"(tRNA-dihydrouridine17 synthase activity)	-	-	-	figure legend:Fig3C, Fig5A, 6|comment:The enzyme was expressed in yeast and  purified with contaminants. However the same experiment was performed with E.coli expressed protein, confirming its enzymatic activity|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/23	2016/05/23	-	rogid:fFy/O8hOonZm+FtvJJRefzNolsU559292	-	false	32p radiolabel:?-?|RNA chemical modification:17-17(23774)	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-11705578	uniprotkb:P53759	rnacentral:URS00000890D0_559292	intact:EBI-27885|uniprotkb:D6W0K3|ensemblfungi:YML080W	psi-mi:trna phe gaa  precursor(display_short)|psi-mi:EBI-11705578(display_long)	psi-mi:dus1_yeast(display_long)|uniprotkb:DUS1(gene name)|psi-mi:DUS1(display_short)|uniprotkb:tRNA-dihydrouridine synthase 1(gene name synonym)|uniprotkb:YML080W(locus name)	psi-mi:"MI:0415"(enzymatic study)	Xing et al. (2002)	pubmed:12003496|imex:IM-25496	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705615|imex:IM-25496-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_013631.1|sgd:S000004545|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|ensemblfungi:YML080W(gene)|ensemblfungi:YML080W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006400"(tRNA modification)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102263"(tRNA-dihydrouridine17 synthase activity)	-	-	-	figure legend:Table 2|comment:The enzyme was expressed in yeast and  purified with contaminants. However the same experiment was performed with E.coli expressed protein, confirming the enzymatic activity|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/23	2016/05/23	-	rogid:fFy/O8hOonZm+FtvJJRefzNolsU559292	-	false	32p radiolabel:?-?|RNA chemical modification:?-?(23774)	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-11705097	uniprotkb:P53759	rnacentral:URS00003653F5_559292	intact:EBI-27885|uniprotkb:D6W0K3|ensemblfungi:YML080W	psi-mi:trna tyr gua  precursor(display_short)|psi-mi:EBI-11705097(display_long)	psi-mi:dus1_yeast(display_long)|uniprotkb:DUS1(gene name)|psi-mi:DUS1(display_short)|uniprotkb:tRNA-dihydrouridine synthase 1(gene name synonym)|uniprotkb:YML080W(locus name)	psi-mi:"MI:0415"(enzymatic study)	Xing et al. (2002)	pubmed:12003496|imex:IM-25496	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705665|imex:IM-25496-5	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_013631.1|sgd:S000004545|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|ensemblfungi:YML080W(gene)|ensemblfungi:YML080W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006400"(tRNA modification)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102263"(tRNA-dihydrouridine17 synthase activity)	-	-	-	figure legend:Fig5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/23	2016/05/23	-	rogid:fFy/O8hOonZm+FtvJJRefzNolsU559292	-	false	32p radiolabel:?-?|RNA chemical modification:?-?(23774)	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P53720	intact:EBI-11705097	intact:EBI-17462|uniprotkb:D6W1J0|ensemblfungi:YNR015W	rnacentral:URS00003653F5_559292	psi-mi:dus2_yeast(display_long)|uniprotkb:SMM1(gene name)|psi-mi:SMM1(display_short)|uniprotkb:DUS2(gene name synonym)|uniprotkb:Protein SMM1(gene name synonym)|uniprotkb:tRNA-dihydrouridine synthase 2(gene name synonym)|uniprotkb:N2065(orf name)|uniprotkb:YNR015W(locus name)	psi-mi:trna tyr gua  precursor(display_short)|psi-mi:EBI-11705097(display_long)	psi-mi:"MI:0415"(enzymatic study)	Xing et al. (2002)	pubmed:12003496|imex:IM-25496	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705702|imex:IM-25496-7	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	refseq:NP_014412.1|sgd:S000005298|ensemblfungi:YNR015W(gene)|ensemblfungi:YNR015W_mRNA(transcript)|go:"GO:0002943"(tRNA dihydrouridine synthesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0008033"(tRNA processing)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102264"(tRNA-dihydrouridine20 synthase activity)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|dip:DIP-4102N	-	-	-	-	figure legend:Fig5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/23	2016/05/23	rogid:fsmm8ARFatW8n17T9Mr4Yrg/yrQ559292	-	-	false	glutathione s tranferase tag:n-n	32p radiolabel:?-?|RNA chemical modification:?-?(23774)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-11705717	uniprotkb:P53720	rnacentral:URS00001346E7_4932	intact:EBI-17462|uniprotkb:D6W1J0|ensemblfungi:YNR015W	psi-mi:trna leu caa precursor(display_short)|psi-mi:EBI-11705717(display_long)	psi-mi:dus2_yeast(display_long)|uniprotkb:SMM1(gene name)|psi-mi:SMM1(display_short)|uniprotkb:DUS2(gene name synonym)|uniprotkb:Protein SMM1(gene name synonym)|uniprotkb:tRNA-dihydrouridine synthase 2(gene name synonym)|uniprotkb:N2065(orf name)|uniprotkb:YNR015W(locus name)	psi-mi:"MI:0415"(enzymatic study)	Xing et al. (2002)	pubmed:12003496|imex:IM-25496	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705720|imex:IM-25496-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_014412.1|sgd:S000005298|ensemblfungi:YNR015W(gene)|ensemblfungi:YNR015W_mRNA(transcript)|go:"GO:0002943"(tRNA dihydrouridine synthesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0008033"(tRNA processing)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102264"(tRNA-dihydrouridine20 synthase activity)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|dip:DIP-4102N	-	-	-	figure legend:Fig5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/23	2016/05/23	-	rogid:fsmm8ARFatW8n17T9Mr4Yrg/yrQ559292	-	false	RNA chemical modification:?-?|32p radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q06063	intact:EBI-11705717	intact:EBI-2343661|uniprotkb:D6VZ38|ensemblfungi:YLR405W	rnacentral:URS00001346E7_4932	psi-mi:dus4_yeast(display_long)|uniprotkb:DUS4(gene name)|psi-mi:DUS4(display_short)|uniprotkb:tRNA-dihydrouridine synthase 4(gene name synonym)|uniprotkb:L8084.2(orf name)|uniprotkb:YLR405W(locus name)	psi-mi:trna leu caa precursor(display_short)|psi-mi:EBI-11705717(display_long)	psi-mi:"MI:0415"(enzymatic study)	Xing et al. (2002)	pubmed:12003496|imex:IM-25496	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705737|imex:IM-25496-11	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	refseq:NP_013509.1|sgd:S000004397|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR018517|interpro:IPR035587|ensemblfungi:YLR405W(gene)|ensemblfungi:YLR405W_mRNA(transcript)|go:"GO:0006400"(tRNA modification)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102266"(tRNA-dihydrouridine20a synthase activity)	-	-	-	-	figure legend:Fig5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/23	2016/05/23	rogid:4nY62HbNNiljODx9O3wxTDn2wSc559292	-	-	false	glutathione s tranferase tag:n-n	RNA chemical modification:?-?|32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)