#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
matrixdb:MULT_12_human	uniprotkb:P02751	intact:EBI-2528478	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:collagen_xiii_human(display_short)|psi-mi:MULT_12_human(display_long)|intact:Collagen type XIII trimer(complex recommended name)|intact:Type XIII collagen(complex synonym)|intact:COL13A1 trimer(complex systematic name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Tu et al. (2002)	pubmed:11956183	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11579151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0008201"(heparin binding)|go:"GO:0005600"(collagen type XIII trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"|complex portal:CPX-1754(complex-primary)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	curated-complex:Nonfibrillar collagen that has been detected at low levels in all connective tissue-producing cells so may serve a general function in connective tissues. Collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. Binds heparin.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	-	figure legend:Fig. 5A, Table II|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.4x10^-9 ~0.2(molar)|kon:1.9x10^6 ~0.03(per mole per second)|koff:4.6x10^-3 ~0.4(second -1)	2016/02/09	2019/10/18	-	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	-	false	sufficient binding region:39-717	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14112	matrixdb:MULT_12_human	intact:EBI-7230848|intact:MINT-1183597|uniprotkb:O43710|uniprotkb:A8K6I7|uniprotkb:B4DU19|ensembl:ENSP00000216286	intact:EBI-2528478	psi-mi:nid2_human(display_long)|uniprotkb:NID2(gene name)|psi-mi:NID2(display_short)|uniprotkb:Osteonidogen(gene name synonym)	psi-mi:collagen_xiii_human(display_short)|psi-mi:MULT_12_human(display_long)|intact:Collagen type XIII trimer(complex recommended name)|intact:Type XIII collagen(complex synonym)|intact:COL13A1 trimer(complex systematic name)	psi-mi:"MI:0107"(surface plasmon resonance)	Tu et al. (2002)	pubmed:11956183	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11579298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1302"(stable complex)	refseq:NP_031387.3|ensembl:ENSG00000087303(gene)|ensembl:ENST00000216286(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071711"(basement membrane organization)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|reactome:R-HSA-3000157	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0008201"(heparin binding)|go:"GO:0005600"(collagen type XIII trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"|complex portal:CPX-1754(complex-primary)	-	comment:mint|comment:homomint|function:Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions	curated-complex:Nonfibrillar collagen that has been detected at low levels in all connective tissue-producing cells so may serve a general function in connective tissues. Collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. Binds heparin.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	figure legend:Fig. 5B, Table II|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.4x10^-9 ~2.0(molar)|kon:1.4x10^6 ~0.3(per mole per second)|koff:7.0x10^-3 ~0.2(second -1)	2016/02/09	2016/02/11	rogid:Ahy+801E9HcohMPyzJs6ZM1o+IY9606	-	-	false	sufficient binding region:31-1375	sufficient binding region:39-717	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
matrixdb:MULT_12_human	uniprotkb:Q05793	intact:EBI-2528478	intact:EBI-1032089	psi-mi:collagen_xiii_human(display_short)|psi-mi:MULT_12_human(display_long)|intact:Collagen type XIII trimer(complex recommended name)|intact:Type XIII collagen(complex synonym)|intact:COL13A1 trimer(complex systematic name)	psi-mi:pgbm_mouse(display_long)|uniprotkb:Hspg2(gene name)|psi-mi:Hspg2(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Tu et al. (2002)	pubmed:11956183	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11579345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0008201"(heparin binding)|go:"GO:0005600"(collagen type XIII trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"|complex portal:CPX-1754(complex-primary)	refseq:NP_032331.2|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR000034(Laminin B)|interpro:IPR001791(Laminin G)|interpro:IPR000082(SEA)|interpro:IPR023415|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002020"(protease binding)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|rcsb pdb:1GL4|reactome:R-MMU-1474228|reactome:R-MMU-1971475|reactome:R-MMU-2022928|reactome:R-MMU-2024096|reactome:R-MMU-216083|reactome:R-MMU-3000157|reactome:R-MMU-3000171|reactome:R-MMU-3000178|reactome:R-MMU-975634|mint:Q05793|interpro:IPR036055|interpro:IPR036179	-	curated-complex:Nonfibrillar collagen that has been detected at low levels in all connective tissue-producing cells so may serve a general function in connective tissues. Collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. Binds heparin.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	-	figure legend:Fig. 5C, Table II|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.5x10^-9 ~0.4(molar)|kon:2.7x10^6 ~0.2(per mole per second)|koff:6.9x10^-3 ~1.4(second -1)	2016/02/09	2016/03/18	-	rogid:cSZXdrVzYrrPDxo2+9QWAlImMbQ10090	-	false	sufficient binding region:39-717	sufficient binding region:22-3707|heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine:65-65,71-71,76-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
matrixdb:MULT_12_human	uniprotkb:P02751	intact:EBI-2528478	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:collagen_xiii_human(display_short)|psi-mi:MULT_12_human(display_long)|intact:Collagen type XIII trimer(complex recommended name)|intact:Type XIII collagen(complex synonym)|intact:COL13A1 trimer(complex systematic name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Tu et al. (2002)	pubmed:11956183	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11579400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0326"(protein)	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0008201"(heparin binding)|go:"GO:0005600"(collagen type XIII trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"|complex portal:CPX-1754(complex-primary)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	curated-complex:Nonfibrillar collagen that has been detected at low levels in all connective tissue-producing cells so may serve a general function in connective tissues. Collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. Binds heparin.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	-	figure legend:Not shown|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:17.5x10^-9(molar)	2016/02/09	2019/10/18	-	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	-	false	sufficient binding region:39-717	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:28304"	matrixdb:MULT_12_human	intact:EBI-1379423	intact:EBI-2528478	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:collagen_xiii_human(display_short)|psi-mi:MULT_12_human(display_long)|intact:Collagen type XIII trimer(complex recommended name)|intact:Type XIII collagen(complex synonym)|intact:COL13A1 trimer(complex systematic name)	psi-mi:"MI:0892"(solid phase assay)	Tu et al. (2002)	pubmed:11956183	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11579467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:1302"(stable complex)	-	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0008201"(heparin binding)|go:"GO:0005600"(collagen type XIII trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"|complex portal:CPX-1754(complex-primary)	-	-	curated-complex:Nonfibrillar collagen that has been detected at low levels in all connective tissue-producing cells so may serve a general function in connective tissues. Collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. Binds heparin.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	figure legend:Fig. 6A|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/02/09	2016/03/21	-	-	-	false	-	sufficient binding region:39-717	-	-	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)
chebi:"CHEBI:28304"	matrixdb:MULT_12_human	intact:EBI-1379423	intact:EBI-2528478	psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long)	psi-mi:collagen_xiii_human(display_short)|psi-mi:MULT_12_human(display_long)|intact:Collagen type XIII trimer(complex recommended name)|intact:Type XIII collagen(complex synonym)|intact:COL13A1 trimer(complex systematic name)	psi-mi:"MI:0004"(affinity chromatography technology)	Tu et al. (2002)	pubmed:11956183	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11579490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:1302"(stable complex)	-	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0008201"(heparin binding)|go:"GO:0005600"(collagen type XIII trimer)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"|complex portal:CPX-1754(complex-primary)	-	-	curated-complex:Nonfibrillar collagen that has been detected at low levels in all connective tissue-producing cells so may serve a general function in connective tissues. Collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. Binds heparin.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	figure legend:Fig. 6B|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/02/09	2016/02/11	-	-	-	false	-	sufficient binding region:39-717	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39060	uniprotkb:P39060	intact:EBI-981314|uniprotkb:Q58EX6|uniprotkb:Q6RZ39|uniprotkb:Q6RZ40|uniprotkb:Q6RZ41|uniprotkb:Q8N4S4|uniprotkb:Q8WXI5|uniprotkb:Q96T70|uniprotkb:Q9UK38|uniprotkb:Q9Y6Q7|uniprotkb:A8MVI4|ensembl:ENSP00000352798|uniprotkb:Q9Y6Q8	intact:EBI-981314|uniprotkb:Q58EX6|uniprotkb:Q6RZ39|uniprotkb:Q6RZ40|uniprotkb:Q6RZ41|uniprotkb:Q8N4S4|uniprotkb:Q8WXI5|uniprotkb:Q96T70|uniprotkb:Q9UK38|uniprotkb:Q9Y6Q7|uniprotkb:A8MVI4|ensembl:ENSP00000352798|uniprotkb:Q9Y6Q8	psi-mi:coia1_human(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short)	psi-mi:coia1_human(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short)	psi-mi:"MI:0016"(circular dichroism)	Tu et al. (2002)	pubmed:11956183	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-11665144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_085059.2|refseq:NP_569712.2|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR020067|interpro:IPR035523|interpro:IPR036790|rcsb pdb:1BNL|rcsb pdb:3HON|rcsb pdb:3HSH|reactome:R-HSA-1442490|reactome:R-HSA-1592389|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8948216|ensembl:ENSG00000182871(gene)|ensembl:ENST00000359759(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR010363(Protein of unknown function DUF959, collagen XVIII, N-terminal)|interpro:IPR010515(Collagenase NC10 and endostatin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_569711.2	refseq:NP_085059.2|refseq:NP_569712.2|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR020067|interpro:IPR035523|interpro:IPR036790|rcsb pdb:1BNL|rcsb pdb:3HON|rcsb pdb:3HSH|reactome:R-HSA-1442490|reactome:R-HSA-1592389|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8948216|ensembl:ENSG00000182871(gene)|ensembl:ENST00000359759(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR010363(Protein of unknown function DUF959, collagen XVIII, N-terminal)|interpro:IPR010515(Collagenase NC10 and endostatin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_569711.2	-	-	-	figure legend:Fig. 3|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.4x10^-9 ~0.2(molar)|kon:1.9x10^6 ~0.03(per mole per second)|koff:4.6x10^-3 ~0.4(second -1)	2016/02/09	2016/03/23	rogid:wLRIpnIxV06w/L+TD0ZldrjEsVs9606	rogid:wLRIpnIxV06w/L+TD0ZldrjEsVs9606	rigid:y39pQ78v/G2RyYQW6QfTyf4dncI	false	sufficient binding region:39-717	sufficient binding region:39-717	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)