#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O17514	uniprotkb:Q9GYS1	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	intact:EBI-314965|uniprotkb:O16187|ensemblmetazoa:C09G4.5.1	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:mes6_caeel(display_long)|uniprotkb:mes-6(gene name)|psi-mi:mes-6(display_short)|uniprotkb:C09G4.5(orf name)|uniprotkb:Maternal-effect sterile protein 6(gene name synonym)|uniprotkb:ESC homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615841|imex:IM-26784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	refseq:NP_001021320.1|wormbase:C09G4.5|interpro:IPR001680(WD40 repeat)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0006342"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0070734"(histone H3-K27 methylation)|ensemblmetazoa:C09G4.5.1(transcript)|ensemblmetazoa:WBGene00003224(gene)|reactome:R-CEL-2559580|reactome:R-CEL-8943724|interpro:IPR036322|interpro:IPR037352|reactome:R-CEL-212300|reactome:R-CEL-8953750	-	-	-	figure legend:Fig 1a, 1B|comment:The anti-MES-2 antibodies were crosslinked to Protein A-agarose beads.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2016/02/29	2016/02/29	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rogid:t3i3sYgrySKRMZglp6t677EHUJo6239	rigid:y7BTxMz39jtHqwdV9cPwgbfO0kc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O17514	uniprotkb:Q10665	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	intact:EBI-322965|uniprotkb:P91324|ensemblmetazoa:F54C1.3a.1	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:mes3_caeel(display_long)|uniprotkb:mes-3(gene name)|psi-mi:mes-3(display_short)|uniprotkb:F54C1.3(orf name)|uniprotkb:Maternal-effect sterile protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615841|imex:IM-26784-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	refseq:NP_001021492.1|wormbase:F54C1.3a|ensemblmetazoa:F54C1.3a.1(transcript)|ensemblmetazoa:WBGene00003221(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0016571"(histone methylation)	-	-	-	figure legend:Fig 1a, 1B|comment:The anti-MES-2 antibodies were crosslinked to Protein A-agarose beads.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2016/02/29	2016/02/29	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rogid:D+3m7TSegvGZspMRqYp3jWTHJxQ6239	rigid:y7BTxMz39jtHqwdV9cPwgbfO0kc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GYS1	uniprotkb:Q10665	intact:EBI-314965|uniprotkb:O16187|ensemblmetazoa:C09G4.5.1	intact:EBI-322965|uniprotkb:P91324|ensemblmetazoa:F54C1.3a.1	psi-mi:mes6_caeel(display_long)|uniprotkb:mes-6(gene name)|psi-mi:mes-6(display_short)|uniprotkb:C09G4.5(orf name)|uniprotkb:Maternal-effect sterile protein 6(gene name synonym)|uniprotkb:ESC homolog(gene name synonym)	psi-mi:mes3_caeel(display_long)|uniprotkb:mes-3(gene name)|psi-mi:mes-3(display_short)|uniprotkb:F54C1.3(orf name)|uniprotkb:Maternal-effect sterile protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615847|imex:IM-26784-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021320.1|wormbase:C09G4.5|interpro:IPR001680(WD40 repeat)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0006342"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0070734"(histone H3-K27 methylation)|ensemblmetazoa:C09G4.5.1(transcript)|ensemblmetazoa:WBGene00003224(gene)|reactome:R-CEL-2559580|reactome:R-CEL-8943724|interpro:IPR036322|interpro:IPR037352|reactome:R-CEL-212300|reactome:R-CEL-8953750	refseq:NP_001021492.1|wormbase:F54C1.3a|ensemblmetazoa:F54C1.3a.1(transcript)|ensemblmetazoa:WBGene00003221(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0016571"(histone methylation)	-	-	-	figure legend:Fig 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2016/02/29	2016/02/29	rogid:t3i3sYgrySKRMZglp6t677EHUJo6239	rogid:D+3m7TSegvGZspMRqYp3jWTHJxQ6239	rigid:y7BTxMz39jtHqwdV9cPwgbfO0kc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GYS1	uniprotkb:O17514	intact:EBI-314965|uniprotkb:O16187|ensemblmetazoa:C09G4.5.1	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	psi-mi:mes6_caeel(display_long)|uniprotkb:mes-6(gene name)|psi-mi:mes-6(display_short)|uniprotkb:C09G4.5(orf name)|uniprotkb:Maternal-effect sterile protein 6(gene name synonym)|uniprotkb:ESC homolog(gene name synonym)	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615847|imex:IM-26784-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021320.1|wormbase:C09G4.5|interpro:IPR001680(WD40 repeat)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0006342"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0070734"(histone H3-K27 methylation)|ensemblmetazoa:C09G4.5.1(transcript)|ensemblmetazoa:WBGene00003224(gene)|reactome:R-CEL-2559580|reactome:R-CEL-8943724|interpro:IPR036322|interpro:IPR037352|reactome:R-CEL-212300|reactome:R-CEL-8953750	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	-	-	-	figure legend:Fig 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2016/02/29	2016/02/29	rogid:t3i3sYgrySKRMZglp6t677EHUJo6239	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rigid:y7BTxMz39jtHqwdV9cPwgbfO0kc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GYS1	uniprotkb:O17514	intact:EBI-314965|uniprotkb:O16187|ensemblmetazoa:C09G4.5.1	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	psi-mi:mes6_caeel(display_long)|uniprotkb:mes-6(gene name)|psi-mi:mes-6(display_short)|uniprotkb:C09G4.5(orf name)|uniprotkb:Maternal-effect sterile protein 6(gene name synonym)|uniprotkb:ESC homolog(gene name synonym)	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615879|imex:IM-26784-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021320.1|wormbase:C09G4.5|interpro:IPR001680(WD40 repeat)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0006342"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0070734"(histone H3-K27 methylation)|ensemblmetazoa:C09G4.5.1(transcript)|ensemblmetazoa:WBGene00003224(gene)|reactome:R-CEL-2559580|reactome:R-CEL-8943724|interpro:IPR036322|interpro:IPR037352|reactome:R-CEL-212300|reactome:R-CEL-8953750	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	-	-	-	comment:The interaction between MES-2 and MES-6 is stable under high salt conditions. Participants were identified by a mix of 2 antibodies, and by molecular weight separation.|figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2016/02/29	2016/02/29	rogid:t3i3sYgrySKRMZglp6t677EHUJo6239	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rigid:fbKvyzzjHqYhbMRk8VEVIkCnufE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GYS1	uniprotkb:O17514	intact:EBI-314965|uniprotkb:O16187|ensemblmetazoa:C09G4.5.1	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	psi-mi:mes6_caeel(display_long)|uniprotkb:mes-6(gene name)|psi-mi:mes-6(display_short)|uniprotkb:C09G4.5(orf name)|uniprotkb:Maternal-effect sterile protein 6(gene name synonym)|uniprotkb:ESC homolog(gene name synonym)	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615860|imex:IM-26784-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021320.1|wormbase:C09G4.5|interpro:IPR001680(WD40 repeat)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0006342"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0070734"(histone H3-K27 methylation)|ensemblmetazoa:C09G4.5.1(transcript)|ensemblmetazoa:WBGene00003224(gene)|reactome:R-CEL-2559580|reactome:R-CEL-8943724|interpro:IPR036322|interpro:IPR037352|reactome:R-CEL-212300|reactome:R-CEL-8953750	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	-	-	-	figure legend:Fig. 2A|comment:Radiolabeled MES-6 was also precipitated by anti-MES-2 in the presence of cold MES-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/02/29	2016/02/29	rogid:t3i3sYgrySKRMZglp6t677EHUJo6239	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rigid:fbKvyzzjHqYhbMRk8VEVIkCnufE	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9GYS1	uniprotkb:O17514	intact:EBI-314965|uniprotkb:O16187|ensemblmetazoa:C09G4.5.1	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	psi-mi:mes6_caeel(display_long)|uniprotkb:mes-6(gene name)|psi-mi:mes-6(display_short)|uniprotkb:C09G4.5(orf name)|uniprotkb:Maternal-effect sterile protein 6(gene name synonym)|uniprotkb:ESC homolog(gene name synonym)	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615868|imex:IM-26784-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021320.1|wormbase:C09G4.5|interpro:IPR001680(WD40 repeat)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0006342"|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0070734"(histone H3-K27 methylation)|ensemblmetazoa:C09G4.5.1(transcript)|ensemblmetazoa:WBGene00003224(gene)|reactome:R-CEL-2559580|reactome:R-CEL-8943724|interpro:IPR036322|interpro:IPR037352|reactome:R-CEL-212300|reactome:R-CEL-8953750	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/02/29	2016/02/29	rogid:t3i3sYgrySKRMZglp6t677EHUJo6239	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rigid:fbKvyzzjHqYhbMRk8VEVIkCnufE	false	35s radiolabel:?-?	35s radiolabel:?-?|sufficient binding region:1-194	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q10665	uniprotkb:O17514	intact:EBI-322965|uniprotkb:P91324|ensemblmetazoa:F54C1.3a.1	intact:EBI-11615731|uniprotkb:O62335|ensemblmetazoa:R06A4.7.1	psi-mi:mes3_caeel(display_long)|uniprotkb:mes-3(gene name)|psi-mi:mes-3(display_short)|uniprotkb:F54C1.3(orf name)|uniprotkb:Maternal-effect sterile protein 3(gene name synonym)	psi-mi:mes2_caeel(display_long)|uniprotkb:"E(z) homolog"(gene name synonym)|uniprotkb:Maternal-effect sterile protein 2(gene name synonym)|uniprotkb:R06A4.7(orf name)|uniprotkb:mes-2(gene name)|psi-mi:mes-2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2001)	pubmed:11320248|imex:IM-26784	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11615891|imex:IM-26784-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021492.1|wormbase:F54C1.3a|ensemblmetazoa:F54C1.3a.1(transcript)|ensemblmetazoa:WBGene00003221(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0016571"(histone methylation)	refseq:NP_496992.3|wormbase:R06A4.7|interpro:IPR026489|interpro:IPR001214(SET)|reactome:R-CEL-8953750|interpro:IPR041355|reactome:R-CEL-212300|ensemblmetazoa:R06A4.7.1(transcript)|ensemblmetazoa:WBGene00003220(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|reactome:R-CEL-2559580|reactome:R-CEL-8943724	-	-	-	comment:Mes-6 is assumed, but not demonstrated, to be present.|figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2016/02/29	2016/02/29	rogid:D+3m7TSegvGZspMRqYp3jWTHJxQ6239	rogid:+XMUNBkZTd9EGy8zjeCBxrBk9Xg6239	rigid:B0eOiuny2rT2+jO5l8sWYYGAy4o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)