#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G3G922 uniprotkb:Q15223 intact:EBI-11691167|uniprotkb:Q5PP78 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:g3g922_9alph(display_long)|uniprotkb:US6(gene name)|psi-mi:US6(display_short) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:10345(pseudorabies virus)|taxid:10345(pseudorabies virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691160|imex:IM-26035-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_068387.1|interpro:IPR002896(Herpesvirus glycoprotein D)|go:"GO:0016021"(integral component of membrane)|interpro:IPR036179 refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 - - - figure legend:6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:QrF6vR5uHNvL7kE/R91FaYwRRe810345 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:FuyKq3fzYAb+6zDedf+P2RkJTzw false sufficient binding region:1-354|his tag:c-c sufficient binding region:1-346|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q69091 uniprotkb:Q15223 intact:EBI-11691180|uniprotkb:B9VQK0|uniprotkb:O12544|uniprotkb:O12833|uniprotkb:P03171|uniprotkb:Q09I71 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:gd_hhv11(display_long)|uniprotkb:gD(gene name)|psi-mi:gD(display_short)|uniprotkb:US6(orf name) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691199|imex:IM-26035-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002896(Herpesvirus glycoprotein D)|refseq:YP_009137141.1|rcsb pdb:3U82|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0055036"(virion membrane)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR036179 refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 - - - figure legend:6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:dLaXbY5E/eEmI2LHf7XgDdzv2c410299 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:cvCdh0unNXuh/L6XiFqIrvW9RCk false sufficient binding region:1-306|his tag:c-c sufficient binding region:1-346|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:G3G922 uniprotkb:Q9GL76 intact:EBI-11691167|uniprotkb:Q5PP78 intact:EBI-11691211 psi-mi:g3g922_9alph(display_long)|uniprotkb:US6(gene name)|psi-mi:US6(display_short) psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:10345(pseudorabies virus)|taxid:10345(pseudorabies virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691233|imex:IM-26035-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_068387.1|interpro:IPR002896(Herpesvirus glycoprotein D)|go:"GO:0016021"(integral component of membrane)|interpro:IPR036179 interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 - - - figure legend:6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:QrF6vR5uHNvL7kE/R91FaYwRRe810345 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rigid:l2PLUBkKy+ScaK6qFEACEGHH56o false sufficient binding region:1-354|his tag:c-c sufficient binding region:31-345|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q69091 uniprotkb:Q9GL76 intact:EBI-11691180|uniprotkb:B9VQK0|uniprotkb:O12544|uniprotkb:O12833|uniprotkb:P03171|uniprotkb:Q09I71 intact:EBI-11691211 psi-mi:gd_hhv11(display_long)|uniprotkb:gD(gene name)|psi-mi:gD(display_short)|uniprotkb:US6(orf name) psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691245|imex:IM-26035-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002896(Herpesvirus glycoprotein D)|refseq:YP_009137141.1|rcsb pdb:3U82|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0055036"(virion membrane)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR036179 interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 - - - figure legend:6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:dLaXbY5E/eEmI2LHf7XgDdzv2c410299 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rigid:6xM2jN0bjLI+qPQn7ceAWyAiSgs false sufficient binding region:1-306|his tag:c-c sufficient binding region:31-345|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9GL76 uniprotkb:G3G922 intact:EBI-11691211 intact:EBI-11691167|uniprotkb:Q5PP78 psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:g3g922_9alph(display_long)|uniprotkb:US6(gene name)|psi-mi:US6(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:10345(pseudorabies virus)|taxid:10345(pseudorabies virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691257|imex:IM-26035-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 refseq:YP_068387.1|interpro:IPR002896(Herpesvirus glycoprotein D)|go:"GO:0016021"(integral component of membrane)|interpro:IPR036179 - - - figure legend:8|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rogid:QrF6vR5uHNvL7kE/R91FaYwRRe810345 rigid:qNub2w0z2G+XGNTQXDwtsdcQy2A false sufficient binding region:31-345|his tag:c-c his tag:c-c|sufficient binding region:1-354 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9GL76 uniprotkb:Q69091 intact:EBI-11691211 intact:EBI-11691180|uniprotkb:B9VQK0|uniprotkb:O12544|uniprotkb:O12833|uniprotkb:P03171|uniprotkb:Q09I71 psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:gd_hhv11(display_long)|uniprotkb:gD(gene name)|psi-mi:gD(display_short)|uniprotkb:US6(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691257|imex:IM-26035-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 interpro:IPR002896(Herpesvirus glycoprotein D)|refseq:YP_009137141.1|rcsb pdb:3U82|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0055036"(virion membrane)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR036179 - - - figure legend:8|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rogid:dLaXbY5E/eEmI2LHf7XgDdzv2c410299 rigid:qNub2w0z2G+XGNTQXDwtsdcQy2A false sufficient binding region:31-345|his tag:c-c sufficient binding region:1-306|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9GL76 uniprotkb:G3G922 intact:EBI-11691211 intact:EBI-11691167|uniprotkb:Q5PP78 psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:g3g922_9alph(display_long)|uniprotkb:US6(gene name)|psi-mi:US6(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:10345(pseudorabies virus)|taxid:10345(pseudorabies virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691274|imex:IM-26035-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 refseq:YP_068387.1|interpro:IPR002896(Herpesvirus glycoprotein D)|go:"GO:0016021"(integral component of membrane)|interpro:IPR036179 - - - figure legend:8|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rogid:QrF6vR5uHNvL7kE/R91FaYwRRe810345 rigid:qNub2w0z2G+XGNTQXDwtsdcQy2A false sufficient binding region:31-345|his tag:c-c his tag:c-c|sufficient binding region:1-354 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9GL76 uniprotkb:Q69091 intact:EBI-11691211 intact:EBI-11691180|uniprotkb:B9VQK0|uniprotkb:O12544|uniprotkb:O12833|uniprotkb:P03171|uniprotkb:Q09I71 psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:gd_hhv11(display_long)|uniprotkb:gD(gene name)|psi-mi:gD(display_short)|uniprotkb:US6(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691274|imex:IM-26035-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 interpro:IPR002896(Herpesvirus glycoprotein D)|refseq:YP_009137141.1|rcsb pdb:3U82|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0055036"(virion membrane)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR036179 - - - figure legend:8|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/04/26 2016/04/26 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rogid:dLaXbY5E/eEmI2LHf7XgDdzv2c410299 rigid:qNub2w0z2G+XGNTQXDwtsdcQy2A false sufficient binding region:31-345|his tag:c-c sufficient binding region:1-306|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:G3G922 uniprotkb:Q9GL76 intact:EBI-11691167|uniprotkb:Q5PP78 intact:EBI-11691211 psi-mi:g3g922_9alph(display_long)|uniprotkb:US6(gene name)|psi-mi:US6(display_short) psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:10345(pseudorabies virus)|taxid:10345(pseudorabies virus) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691322|imex:IM-26035-13 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_068387.1|interpro:IPR002896(Herpesvirus glycoprotein D)|go:"GO:0016021"(integral component of membrane)|interpro:IPR036179 interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 - - - figure legend:9 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.9x10^-7(molar) 2016/04/26 2016/04/26 rogid:QrF6vR5uHNvL7kE/R91FaYwRRe810345 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rigid:l2PLUBkKy+ScaK6qFEACEGHH56o false sufficient binding region:1-354|his tag:c-c sufficient binding region:31-345|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q69091 uniprotkb:Q9GL76 intact:EBI-11691180|uniprotkb:B9VQK0|uniprotkb:O12544|uniprotkb:O12833|uniprotkb:P03171|uniprotkb:Q09I71 intact:EBI-11691211 psi-mi:gd_hhv11(display_long)|uniprotkb:gD(gene name)|psi-mi:gD(display_short)|uniprotkb:US6(orf name) psi-mi:nect1_pig(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Milne et al. (2001) pubmed:11277703|imex:IM-26035 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11691351|imex:IM-26035-15 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002896(Herpesvirus glycoprotein D)|refseq:YP_009137141.1|rcsb pdb:3U82|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0055036"(virion membrane)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR036179 interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033314|rcsb pdb:5X5W|refseq:NP_001001262.1|refseq:XP_003130000.5|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR041849|interpro:IPR041850|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR036179 - - - figure legend:9 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.9x10^-6(molar) 2016/04/26 2016/04/26 rogid:dLaXbY5E/eEmI2LHf7XgDdzv2c410299 rogid:OIHGZtAQiO0KE10VNvyOHAXaLjE9823 rigid:6xM2jN0bjLI+qPQn7ceAWyAiSgs false sufficient binding region:1-306|his tag:c-c sufficient binding region:31-345|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)