#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00546 uniprotkb:P20438 intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W intact:EBI-4483|uniprotkb:E9P938|uniprotkb:D6W3B5|ensemblfungi:YPL256C psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:cg12_yeast(display_long)|uniprotkb:CLN2(gene name)|psi-mi:CLN2(display_short)|uniprotkb:YPL256C(locus name) psi-mi:"MI:0096"(pull down) Reynard et al. (2000) pubmed:10913169|imex:IM-25012 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580050|imex:IM-25012-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656 refseq:NP_015067.1|sgd:S000006177|dip:DIP-2270N|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YPL256C(gene)|ensemblfungi:YPL256C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR014399(G1 cyclin, CLN1/CLN2/Puc1)|interpro:IPR036915|interpro:IPR039361 - crc64:57A7A2B97A90DC6C crc64:D6426B94E040E960 figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/02/12 2016/02/12 rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292 rogid:iJ+vDdbwApGApbN713jiPPFsY2o559292 rigid:mw4SrjuQAt3n7VgRMwxPOyp7U1E false ha tag:c-c|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P00546 uniprotkb:P20486 intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W intact:EBI-4746|uniprotkb:D6VQD1|ensemblfungi:YBR135W psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:cks1_yeast(display_long)|uniprotkb:CKS1(gene name)|psi-mi:CKS1(display_short)|uniprotkb:YBR135W(locus name)|uniprotkb:YBR1011(orf name)|uniprotkb:Cell division control protein CKS1(gene name synonym) psi-mi:"MI:0096"(pull down) Reynard et al. (2000) pubmed:10913169|imex:IM-25012 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580050|imex:IM-25012-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656 sgd:S000000339|refseq:NP_009693.3|ensemblfungi:YBR135W(gene)|ensemblfungi:YBR135W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|rcsb pdb:1QB3|rcsb pdb:3QY2|rcsb pdb:4LPA|dip:DIP-1262N|mint:P20486 - crc64:57A7A2B97A90DC6C crc64:0DD0910E01D373FF figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/02/12 2016/02/12 rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292 rogid:rIKlEGjrs3WOX8MT+JUrspVXSzs559292 rigid:mw4SrjuQAt3n7VgRMwxPOyp7U1E false ha tag:c-c|glutathione s tranferase tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P00546 uniprotkb:P20438 intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W intact:EBI-4483|uniprotkb:E9P938|uniprotkb:D6W3B5|ensemblfungi:YPL256C psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:cg12_yeast(display_long)|uniprotkb:CLN2(gene name)|psi-mi:CLN2(display_short)|uniprotkb:YPL256C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reynard et al. (2000) pubmed:10913169|imex:IM-25012 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580069|imex:IM-25012-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656 refseq:NP_015067.1|sgd:S000006177|dip:DIP-2270N|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YPL256C(gene)|ensemblfungi:YPL256C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR014399(G1 cyclin, CLN1/CLN2/Puc1)|interpro:IPR036915|interpro:IPR039361 - crc64:57A7A2B97A90DC6C crc64:D6426B94E040E960 figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2016/02/12 2016/02/12 rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292 rogid:iJ+vDdbwApGApbN713jiPPFsY2o559292 rigid:5hlBcsK32XJEqK66pggHsq1IbqA false ha tag:?-? myc tag:?-?|his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P00546 uniprotkb:P20438 intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W intact:EBI-4483|uniprotkb:E9P938|uniprotkb:D6W3B5|ensemblfungi:YPL256C psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:cg12_yeast(display_long)|uniprotkb:CLN2(gene name)|psi-mi:CLN2(display_short)|uniprotkb:YPL256C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reynard et al. (2000) pubmed:10913169|imex:IM-25012 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580155|imex:IM-25012-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656 refseq:NP_015067.1|sgd:S000006177|dip:DIP-2270N|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YPL256C(gene)|ensemblfungi:YPL256C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR014399(G1 cyclin, CLN1/CLN2/Puc1)|interpro:IPR036915|interpro:IPR039361 - crc64:57A7A2B97A90DC6C crc64:D6426B94E040E960 figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/02/12 2016/02/12 rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292 rogid:iJ+vDdbwApGApbN713jiPPFsY2o559292 rigid:5hlBcsK32XJEqK66pggHsq1IbqA false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P00546 uniprotkb:P13365 intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W intact:EBI-4490|uniprotkb:D6VPH6|uniprotkb:E9P940|ensemblfungi:YAL040C psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:cg13_yeast(display_long)|uniprotkb:CLN3(gene name)|psi-mi:CLN3(display_short)|uniprotkb:DAF1(gene name synonym)|uniprotkb:WHI1(gene name synonym)|uniprotkb:YAL040C(locus name)|uniprotkb:FUN10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reynard et al. (2000) pubmed:10913169|imex:IM-25012 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11580170|imex:IM-25012-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656 refseq:NP_009360.1|sgd:S000000038|dip:DIP-1267N|ensemblfungi:YAL040C(gene)|ensemblfungi:YAL040C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007033"(vacuole organization)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028857|interpro:IPR036915|interpro:IPR039361 - crc64:57A7A2B97A90DC6C crc64:AF6950A7E68DB295 figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/02/12 2016/02/12 rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292 rogid:hJLh3Py/9bg4005m8/uQaT0TcFg559292 rigid:YWUQC1T8gvhF8EZbfTD+W2A2NcE false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)