#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11277 uniprotkb:P50463 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 intact:EBI-12502290 psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12504590|imex:IM-25587-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/08/11 2016/08/11 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false sufficient binding region:890-1290(IPR002017) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11277 uniprotkb:P50463 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 intact:EBI-12502290 psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12504604|imex:IM-25587-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 - - - figure legend:Table 1, fig 3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/08/11 2016/08/11 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false sufficient binding region:890-1290(IPR002017) sufficient binding region:110-194(IPR001781) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11277 uniprotkb:P50463 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 intact:EBI-12502290 psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0096"(pull down) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12504622|imex:IM-25587-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/11 2016/08/11 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false sufficient binding region:890-1290(IPR002017)|35s radiolabel:?-? his tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P10085 uniprotkb:P50463 intact:EBI-4405734|uniprotkb:Q8C6B1|ensembl:ENSMUSP00000072330 intact:EBI-12502290 psi-mi:myod1_mouse(display_long)|uniprotkb:Myod1(gene name)|psi-mi:Myod1(display_short)|uniprotkb:Myod(gene name synonym) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0096"(pull down) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12504634|imex:IM-25587-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034996.2|dip:DIP-37N|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014902"(myotube differentiation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|ensembl:ENSMUSG00000009471(gene)|ensembl:ENSMUST00000072514(transcript)|interpro:IPR036638|interpro:IPR039704|mint:P10085|rcsb pdb:1MDY|reactome:R-MMU-525793|interpro:IPR022032 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/11 2016/08/11 rogid:9GpR7O8xYPiQXHqrlxB/HioqgJM10090 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:JPgMGADtJlPd1jc9FeT90bzPlGw false 35s radiolabel:?-? his tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P11277 uniprotkb:P50463 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 intact:EBI-12502290 psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0096"(pull down) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12504791|imex:IM-25587-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 - - - figure legend:2C and 3B|comment:"alpha-actinin also copurified but cannot be mapped to a specific protein (chicken ACTN1 or ACTN2)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/11 2016/08/11 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false sufficient binding region:890-1290(IPR002017)|35s radiolabel:?-? glutathione s tranferase tag:?-?|sufficient binding region:110-194(IPR001781) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P11277 uniprotkb:P50463 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 intact:EBI-12502290 psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0096"(pull down) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12551873|imex:IM-25587-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/11 2016/09/28 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false 35s radiolabel:?-?|sufficient binding region:925-1031(IPR002017) glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P50463 uniprotkb:P11277 intact:EBI-12502290 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:"MI:0096"(pull down) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12551892|imex:IM-25587-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 - - - figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/11 2016/10/19 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false glutathione s tranferase tag:?-? his tag:?-?|sufficient binding region:925-1349 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P50463 uniprotkb:P11277 intact:EBI-12502290 intact:EBI-514908|uniprotkb:Q15510|uniprotkb:Q15519|ensembl:ENSP00000374370 psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:sptb1_human(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym) psi-mi:"MI:0096"(pull down) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12551892|imex:IM-25587-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 refseq:NP_000338.3|refseq:NP_001020029.1|refseq:XP_005268080.1|refseq:XP_016877101.1|refseq:XP_016877103.1|dip:DIP-1021N|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389720(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1S35|rcsb pdb:3EDU|rcsb pdb:3F57|rcsb pdb:3KBT|rcsb pdb:3KBU|rcsb pdb:3LBX|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878 - - - figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/11 2016/10/19 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rogid:pMUYFaSR/cKouM4GMi36sGK6aOU9606 rigid:NiXowhpJXRJCVB59Uw26i3zrEiU false glutathione s tranferase tag:?-? sufficient binding region:890-1290(IPR002017)|35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P50463 uniprotkb:P11277-2 intact:EBI-12502290 intact:EBI-12504851|ensembl:ENSP00000374372|ensembl:ENSP00000495909 psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:p11277-2(display_long)|uniprotkb:Beta-I spectrin(gene name synonym)|uniprotkb:SPTB(gene name)|psi-mi:SPTB(display_short)|uniprotkb:SPTB1(gene name synonym)|uniprotkb:Muscle-specific(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12504842|imex:IM-25587-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 intact:EBI-514908(isoform-parent)|uniprotkb:P11277-2(isoform-parent)|ensembl:ENSG00000070182(gene)|ensembl:ENST00000389722(transcript)|ensembl:ENST00000644917(transcript) - - - figure legend:6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/08/11 2016/08/11 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rogid:sM+3dJb/F/Sc4m/PODPBQhYymcY9606 rigid:b5kacC7MjvWAsf1X8DA+Jh4ErG0 false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A0A140UHX6 uniprotkb:P50463 intact:EBI-12504875|ensembl:ENSRNOP00000009028 intact:EBI-12502290 psi-mi:a0a140uhx6_rat(display_long)|uniprotkb:Sptb(gene name)|psi-mi:Sptb(display_short) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12504896|imex:IM-25587-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006911(gene)|ensembl:ENSRNOT00000009028(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6807878|refseq:XP_006240306.1|refseq:XP_017449631.1|refseq:XP_017449632.1|rgd:1303243 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:8 and 9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1016(rat-skeletal_muscle)|taxid:1016(rat skeletal muscle) - 2016/08/11 2016/08/11 rogid:RIo5sqmS+Iv5dGnQItgXsGaiBxc10116 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:3zGmUxubdk81DfYSgM5WlJqv2FE false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:A0A140UHX6 uniprotkb:P50463 intact:EBI-12504875|ensembl:ENSRNOP00000009028 intact:EBI-12502290 psi-mi:a0a140uhx6_rat(display_long)|uniprotkb:Sptb(gene name)|psi-mi:Sptb(display_short) psi-mi:csrp3_rat(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Flick et al. (2000) imex:IM-25587|pubmed:10751147 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12504913|imex:IM-25587-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006911(gene)|ensembl:ENSRNOT00000009028(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6807878|refseq:XP_006240306.1|refseq:XP_017449631.1|refseq:XP_017449632.1|rgd:1303243 go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|refseq:NP_476485.1|interpro:IPR001781(Zinc finger, LIM-type)|rgd:71092 go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band) - - figure legend:7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-cardiac muscle)|taxid:10116(Rattus norvegicus) - 2016/08/11 2016/08/11 rogid:RIo5sqmS+Iv5dGnQItgXsGaiBxc10116 rogid:PBZ1rLyhU5alJfks7sO9+Ml9LAY10116 rigid:3zGmUxubdk81DfYSgM5WlJqv2FE false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)