#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12330 uniprotkb:P54999 intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11435561|imex:IM-25729-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V - crc64:B76D72DA8456F3B5 crc64:1640D3237597B2D8 figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:m81oQTRru52/v6dQB1mkmCwcbF0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40204 uniprotkb:Q12330 intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11435618|imex:IM-25729-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 - crc64:5C6208B8C5A9AB33 crc64:B76D72DA8456F3B5 figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rigid:20GOAyiX5+zGH5ZxDqv80FrQiHE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12330 uniprotkb:P54999 intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11436438|imex:IM-25729-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V - crc64:B76D72DA8456F3B5 crc64:1640D3237597B2D8 figure legend:Table 1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:m81oQTRru52/v6dQB1mkmCwcbF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12330 uniprotkb:P54999 intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11436582|imex:IM-25729-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V - crc64:B76D72DA8456F3B5 crc64:1640D3237597B2D8 figure legend:Table 1, Table 2, Table 3|comment:Stop mutations at trp-30, gly-45, leu-82 and leu-89 of SME1 prevented binding to SMF1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:m81oQTRru52/v6dQB1mkmCwcbF0 false mutation disrupting interaction strength:22-22|mutation disrupting interaction strength:47-47|mutation disrupting interaction strength:81-81|mutation disrupting interaction strength:27-27|mutation disrupting interaction strength:29-29|mutation disrupting interaction strength:41-41|mutation disrupting interaction strength:54-54|mutation disrupting interaction strength:47-47|mutation decreasing interaction strength:90-90|mutation decreasing interaction strength:50-50|mutation decreasing interaction strength:51-51|mutation decreasing interaction strength:80-80|mutation decreasing interaction strength:84-84|mutation increasing interaction strength:3-3|mutation with no effect:6-6|mutation with no effect:10-10|mutation with no effect:31-31|mutation with no effect:45-45|mutation with no effect:59-59,63-63|mutation with no effect:76-76|mutation with no effect:84-84 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40204 uniprotkb:Q12330 intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11436671|imex:IM-25729-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 - crc64:5C6208B8C5A9AB33 crc64:B76D72DA8456F3B5 figure legend:Table 1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rigid:20GOAyiX5+zGH5ZxDqv80FrQiHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12904 uniprotkb:P06782 intact:EBI-17537|ensemblfungi:YGL115W|uniprotkb:D6VU32 intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W psi-mi:aakg_yeast(display_long)|uniprotkb:SNF4(gene name)|psi-mi:SNF4(display_short)|uniprotkb:CAT3(gene name synonym)|uniprotkb:Regulatory protein CAT3(gene name synonym)|uniprotkb:SCI1(gene name synonym)|uniprotkb:Sucrose non-fermenting protein 4(gene name synonym)|uniprotkb:YGL115W(locus name) psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11436882|imex:IM-25729-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|ensemblfungi:YGL115W(gene)|ensemblfungi:YGL115W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|refseq:NP_011400.1|sgd:S000003083|go:"GO:0007031"(peroxisome organization)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|rcsb pdb:2NYC|rcsb pdb:2NYE|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|dip:DIP-592N|mint:P12904 refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782 - crc64:51B387E346EE9561 crc64:F5C63565C986C4E3 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:dYtx5LQZtt2QZX/VelN4akMH7KA559292 rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292 rigid:4MHnCvJEe/pauqdj+JsPSZ8Bj+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43321 uniprotkb:P40018 intact:EBI-529|ensemblfungi:YLR147C|uniprotkb:D6VYE2|uniprotkb:E9P8W3 intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C psi-mi:smd3_yeast(display_long)|uniprotkb:SMD3(gene name)|psi-mi:SMD3(display_short)|uniprotkb:YLR147C(locus name)|uniprotkb:L9634.6(orf name)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11437235|imex:IM-25729-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013248.1|sgd:S000004137|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YLR147C(gene)|ensemblfungi:YLR147C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|dip:DIP-715N|mint:P43321 sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 - crc64:BB02A56C5AD70CF2 crc64:0A1078D5AA241430 figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:ueJ4D76t8ilvz/p9qMzIGiCzqWk559292 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rigid:IZYw48e6xolRvHHLbwoAFL3NGgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43321 uniprotkb:P40018 intact:EBI-529|ensemblfungi:YLR147C|uniprotkb:D6VYE2|uniprotkb:E9P8W3 intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C psi-mi:smd3_yeast(display_long)|uniprotkb:SMD3(gene name)|psi-mi:SMD3(display_short)|uniprotkb:YLR147C(locus name)|uniprotkb:L9634.6(orf name)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11437409|imex:IM-25729-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013248.1|sgd:S000004137|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YLR147C(gene)|ensemblfungi:YLR147C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|dip:DIP-715N|mint:P43321 sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 - crc64:BB02A56C5AD70CF2 crc64:0A1078D5AA241430 figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:ueJ4D76t8ilvz/p9qMzIGiCzqWk559292 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rigid:IZYw48e6xolRvHHLbwoAFL3NGgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12330 uniprotkb:P40204 intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0018"(two hybrid) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11440097|imex:IM-25729-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO - crc64:B76D72DA8456F3B5 crc64:5C6208B8C5A9AB33 figure legend:Table 1, Table 2, Table 3|comment:Stop mutations at trp-30, gly-45, leu-82 of SME1 prevented binding to SMX2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/12/04 2015/12/04 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rigid:20GOAyiX5+zGH5ZxDqv80FrQiHE false mutation disrupting interaction strength:41-41|mutation disrupting interaction strength:54-54|mutation decreasing interaction strength:47-47|mutation disrupting interaction strength:90-90|mutation decreasing interaction strength:50-50|mutation disrupting interaction strength:22-22|mutation decreasing interaction strength:47-47|mutation disrupting interaction strength:27-27|mutation disrupting interaction strength:29-29|mutation decreasing interaction strength:86-86|mutation with no effect:81-81|mutation with no effect:3-3|mutation with no effect:6-6|mutation with no effect:10-10|mutation with no effect:31-31|mutation with no effect:45-45|mutation with no effect:51-51|mutation with no effect:59-59,63-63|mutation with no effect:76-76|mutation with no effect:80-80|mutation with no effect:83-83|mutation with no effect:84-84 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12330 uniprotkb:P54999 intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C intact:EBI-770|uniprotkb:D6W4I2|ensemblfungi:YPR182W psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxf_yeast(display_long)|uniprotkb:SMX3(gene name)|psi-mi:SMX3(display_short)|uniprotkb:YPR182W(locus name)|uniprotkb:P9705.4(orf name)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0096"(pull down) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11438192|imex:IM-25729-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 refseq:NP_015508.1|sgd:S000006386|dip:DIP-1634N|mint:P54999|ensemblfungi:YPR182W(gene)|ensemblfungi:YPR182W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|rcsb pdb:1N9R|rcsb pdb:1N9S|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V - crc64:B76D72DA8456F3B5 crc64:1640D3237597B2D8 figure legend:Fig. 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/12/04 2015/12/04 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rogid:iyBbVNf2fgOIqhnOg9Etn3P2r3Q559292 rigid:m81oQTRru52/v6dQB1mkmCwcbF0 false glutathione s tranferase tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q12330 uniprotkb:P40204 intact:EBI-16359|uniprotkb:D6W2L6|ensemblfungi:YOR159C intact:EBI-637|uniprotkb:D6VTL2|ensemblfungi:YFL017W-A psi-mi:ruxe_yeast(display_long)|uniprotkb:SME1(gene name)|psi-mi:SME1(display_short)|uniprotkb:YOR159C(locus name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxg_yeast(display_long)|uniprotkb:SNP2(gene name synonym)|uniprotkb:YFL017Bw(orf name)|uniprotkb:YFL017W-A(locus name)|uniprotkb:SMX2(gene name)|psi-mi:SMX2(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0096"(pull down) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11438225|imex:IM-25729-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR159C(gene)|ensemblfungi:YOR159C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|sgd:S000005685|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|refseq:NP_014802.3|dip:DIP-1633N|mint:Q12330 refseq:NP_116636.1|sgd:S000002965|dip:DIP-6683N|mint:P40204|ensemblfungi:YFL017W-A(gene)|ensemblfungi:YFL017W-A_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|rcsb pdb:7DCO - crc64:B76D72DA8456F3B5 crc64:5C6208B8C5A9AB33 figure legend:Fig. 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/12/04 2015/12/04 rogid:IiV/AXz4zJjC7A2iuBixxiLYo9E559292 rogid:Wh37rGoSJFpJ5o+CuNkBnpiu/5s559292 rigid:20GOAyiX5+zGH5ZxDqv80FrQiHE false mutation disrupting interaction strength:22-22|glutathione s tranferase tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P43321 uniprotkb:P40018 intact:EBI-529|ensemblfungi:YLR147C|uniprotkb:D6VYE2|uniprotkb:E9P8W3 intact:EBI-432|uniprotkb:D3DLS8|ensemblfungi:YER029C psi-mi:smd3_yeast(display_long)|uniprotkb:SMD3(gene name)|psi-mi:SMD3(display_short)|uniprotkb:YLR147C(locus name)|uniprotkb:L9634.6(orf name)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:rsmb_yeast(display_long)|uniprotkb:SMB1(gene name)|psi-mi:SMB1(display_short)|uniprotkb:Sm protein B(gene name synonym)|uniprotkb:YER029C(locus name) psi-mi:"MI:0096"(pull down) Camasses et al. (1998) imex:IM-25729|pubmed:9528767 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11438574|imex:IM-25729-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013248.1|sgd:S000004137|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YLR147C(gene)|ensemblfungi:YLR147C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|dip:DIP-715N|mint:P43321 sgd:S000000831|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWN|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|rcsb pdb:7B9V|ensemblfungi:YER029C(gene)|ensemblfungi:YER029C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GM6|refseq:NP_010946.3|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|dip:DIP-843N|mint:P40018 - crc64:BB02A56C5AD70CF2 crc64:0A1078D5AA241430 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/12/04 2015/12/04 rogid:ueJ4D76t8ilvz/p9qMzIGiCzqWk559292 rogid:b62+dBOdvQgeE0oup4kbXbviS1U559292 rigid:IZYw48e6xolRvHHLbwoAFL3NGgk false 35s radiolabel:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)