#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21272	uniprotkb:P21272	intact:EBI-5333201|uniprotkb:A2VD03|ensembl:ENSRNOP00000071427	intact:EBI-5333201|uniprotkb:A2VD03|ensembl:ENSRNOP00000071427	psi-mi:cebpb_rat(display_long)|uniprotkb:Cebpb(gene name)|psi-mi:Cebpb(display_short)|uniprotkb:Crp2(gene name synonym)|uniprotkb:Sfb(gene name synonym)|uniprotkb:C/EBP-related protein 2(gene name synonym)|uniprotkb:Interleukin-6-dependent-binding protein(gene name synonym)|uniprotkb:Liver-enriched transcriptional activator(gene name synonym)|uniprotkb:Silencer factor B(gene name synonym)|uniprotkb:Nf-il6(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:cebpb_rat(display_long)|uniprotkb:Cebpb(gene name)|psi-mi:Cebpb(display_short)|uniprotkb:Crp2(gene name synonym)|uniprotkb:Sfb(gene name synonym)|uniprotkb:C/EBP-related protein 2(gene name synonym)|uniprotkb:Interleukin-6-dependent-binding protein(gene name synonym)|uniprotkb:Liver-enriched transcriptional activator(gene name synonym)|uniprotkb:Silencer factor B(gene name synonym)|uniprotkb:Nf-il6(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10634483|imex:IM-23839-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-28139N|refseq:NP_001288644.1|refseq:NP_001288649.1|rgd:2327|refseq:NP_077039.3|ensembl:ENSRNOG00000057347(gene)|ensembl:ENSRNOT00000083876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-RNO-2559582	dip:DIP-28139N|refseq:NP_001288644.1|refseq:NP_001288649.1|rgd:2327|refseq:NP_077039.3|ensembl:ENSRNOG00000057347(gene)|ensembl:ENSRNOT00000083876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-RNO-2559582	-	-	-	figure legend:"Fig. 1a (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver)	-	2015/02/16	2015/03/05	rogid:D+qA22lPDh4z711PKJ6zJjUjClU10116	rogid:D+qA22lPDh4z711PKJ6zJjUjClU10116	intact-crc:D2EE68DE59927DB2|rigid:Xj20t7A0m9q4Cwf2TrrTRrGPICI	false	sufficient binding region:221..223-286..286(IPR004827)|32p radiolabel:?-?|tag:n-n	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P21272	uniprotkb:Q62857	intact:EBI-5333201|uniprotkb:A2VD03|ensembl:ENSRNOP00000071427	intact:EBI-10634485	psi-mi:cebpb_rat(display_long)|uniprotkb:Cebpb(gene name)|psi-mi:Cebpb(display_short)|uniprotkb:Crp2(gene name synonym)|uniprotkb:Sfb(gene name synonym)|uniprotkb:C/EBP-related protein 2(gene name synonym)|uniprotkb:Interleukin-6-dependent-binding protein(gene name synonym)|uniprotkb:Liver-enriched transcriptional activator(gene name synonym)|uniprotkb:Silencer factor B(gene name synonym)|uniprotkb:Nf-il6(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:ddit3_rat(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10634483|imex:IM-23839-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-28139N|refseq:NP_001288644.1|refseq:NP_001288649.1|rgd:2327|refseq:NP_077039.3|ensembl:ENSRNOG00000057347(gene)|ensembl:ENSRNOT00000083876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-RNO-2559582	rgd:62391|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001554"(luteolysis)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)	-	-	-	figure legend:"Fig. 1a (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver)	-	2015/02/16	2015/03/05	rogid:D+qA22lPDh4z711PKJ6zJjUjClU10116	rogid:XTgJa5gMJs+LLObS0URbmmbHu5Y10116	intact-crc:D2EE68DE59927DB2|rigid:Xj20t7A0m9q4Cwf2TrrTRrGPICI	false	sufficient binding region:221..223-286..286(IPR004827)|32p radiolabel:?-?|tag:n-n	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P05554	uniprotkb:Q62857	intact:EBI-1172084	intact:EBI-10634485	psi-mi:cebpa_rat(display_long)|uniprotkb:Cebpa(gene name)|psi-mi:Cebpa(display_short)	psi-mi:ddit3_rat(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10634929|imex:IM-23839-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006953"(acute-phase response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0007613"(memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033274"(response to vitamin B2)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035690"|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|rcsb pdb:1NWQ|go:"GO:0045444"(fat cell differentiation)|rgd:2326|refseq:NP_036656.1|refseq:NP_001274506.1|refseq:NP_001274507.1|refseq:NP_001274508.1|dip:DIP-28138N|reactome:R-RNO-9616222	rgd:62391|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001554"(luteolysis)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)	-	-	-	figure legend:"Fig. 2a (blot 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/16	2015/03/05	rogid:Vfdg4r7UPy8Ce0i2t3Br4TE2lkM10116	rogid:XTgJa5gMJs+LLObS0URbmmbHu5Y10116	intact-crc:995F16BECB0E8215|rigid:q/2Y5JUDmRfbn/+iG2MyMi57H+g	false	glutathione s tranferase tag:?-?|sufficient binding region:304-358(IPR004827)	glutathione s tranferase tag:?-?|32p radiolabel:107-107	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q62857	uniprotkb:P17676	intact:EBI-10634485	intact:EBI-969696|intact:EBI-28973829|ensembl:ENSP00000305422|uniprotkb:Q96IH2|uniprotkb:Q9H4Z5|uniprotkb:A8K671	psi-mi:ddit3_rat(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym)	psi-mi:cebpb_human(display_long)|uniprotkb:CEBPB(gene name)|psi-mi:CEBPB(display_short)|uniprotkb:TCF5(gene name synonym)|uniprotkb:PP9092(orf name)|uniprotkb:Liver activator protein(gene name synonym)|uniprotkb:Nuclear factor NF-IL6(gene name synonym)|uniprotkb:Transcription factor 5(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10634933|imex:IM-23839-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:62391|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001554"(luteolysis)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)	refseq:NP_001272807.1|refseq:NP_001272808.1|ensembl:ENSG00000172216(gene)|ensembl:ENST00000303004(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006953"(acute-phase response)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007613"(memory)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P17676|rcsb pdb:1GTW|rcsb pdb:1GU4|rcsb pdb:1GU5|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1H8A|rcsb pdb:1HJB|rcsb pdb:1IO4|rcsb pdb:2E42|rcsb pdb:2E43|rcsb pdb:6MG1|rcsb pdb:6MG2|rcsb pdb:6MG3|reactome:R-HSA-2559582|reactome:R-HSA-380994|reactome:R-HSA-381340|reactome:R-HSA-8853884|reactome:R-HSA-9616222|reactome:R-HSA-9633012|reactome:R-HSA-9648895|ensembl:ENSP00000305422|refseq:NP_005185.2|dip:DIP-35345N	-	-	-	figure legend:"Fig. 2a (blot 1)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/16	2015/03/05	rogid:XTgJa5gMJs+LLObS0URbmmbHu5Y10116	rogid:RZKdnZRt48VZoER/NDVHSDFzqEA9606	intact-crc:CE67ECE2DD679830|rigid:6QLpFcFt9Ge77Y5O1wdYIY9vOUw	false	32p radiolabel:107-107|glutathione s tranferase tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:294-345(IPR004827)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10635507	uniprotkb:P17676	-	intact:EBI-969696|intact:EBI-28973829|ensembl:ENSP00000305422|uniprotkb:Q96IH2|uniprotkb:Q9H4Z5|uniprotkb:A8K671	psi-mi:camre(display_short)|psi-mi:EBI-10635507(display_long)	psi-mi:cebpb_human(display_long)|uniprotkb:CEBPB(gene name)|psi-mi:CEBPB(display_short)|uniprotkb:TCF5(gene name synonym)|uniprotkb:PP9092(orf name)|uniprotkb:Liver activator protein(gene name synonym)|uniprotkb:Nuclear factor NF-IL6(gene name synonym)|uniprotkb:Transcription factor 5(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635491|imex:IM-23839-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	pubmed:1314426(see-also)	refseq:NP_001272807.1|refseq:NP_001272808.1|ensembl:ENSG00000172216(gene)|ensembl:ENST00000303004(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006953"(acute-phase response)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007613"(memory)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P17676|rcsb pdb:1GTW|rcsb pdb:1GU4|rcsb pdb:1GU5|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1H8A|rcsb pdb:1HJB|rcsb pdb:1IO4|rcsb pdb:2E42|rcsb pdb:2E43|rcsb pdb:6MG1|rcsb pdb:6MG2|rcsb pdb:6MG3|reactome:R-HSA-2559582|reactome:R-HSA-380994|reactome:R-HSA-381340|reactome:R-HSA-8853884|reactome:R-HSA-9616222|reactome:R-HSA-9633012|reactome:R-HSA-9648895|ensembl:ENSP00000305422|refseq:NP_005185.2|dip:DIP-35345N	-	-	-	figure legend:Fig. 6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/16	2015/03/05	-	rogid:RZKdnZRt48VZoER/NDVHSDFzqEA9606	intact-crc:5F0FD2C330B3F3F4	false	32p radiolabel:?-?	sufficient binding region:294-345(IPR004827)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10635507	uniprotkb:Q62857	-	intact:EBI-10634485	psi-mi:camre(display_short)|psi-mi:EBI-10635507(display_long)	psi-mi:ddit3_rat(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635491|imex:IM-23839-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	pubmed:1314426(see-also)	rgd:62391|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001554"(luteolysis)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)	-	-	-	figure legend:Fig. 6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/16	2015/03/05	-	rogid:XTgJa5gMJs+LLObS0URbmmbHu5Y10116	intact-crc:5F0FD2C330B3F3F4	false	32p radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10635507	uniprotkb:P35639	-	intact:EBI-10636142|uniprotkb:Q91YW9|ensembl:ENSMUSP00000026475	psi-mi:camre(display_short)|psi-mi:EBI-10635507(display_long)	psi-mi:ddit3_mouse(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym)	psi-mi:"MI:0412"(electrophoretic mobility supershift assay)	Ubeda et al. (1996)	pubmed:8657121|imex:IM-23839	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10636133|imex:IM-23839-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	pubmed:1314426(see-also)	refseq:NP_001277112.1|refseq:NP_031863.3|refseq:XP_006513260.1|ensembl:ENSMUSG00000025408(gene)|ensembl:ENSMUST00000026475(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|dip:DIP-60705N	-	-	-	figure legend:"Fig. 6c (lane 3)"|comment:"Supershifted with monoclonal antibody 3H8 against CHOP (ddit3)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells)	-	2015/02/16	2015/03/05	-	rogid:ltrRdLwc8dwkKYkmxIAmq4iuFfA10090	intact-crc:A2F68FC894370AC5	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)