#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P09481	uniprotkb:P26152	intact:EBI-10686191|ensembl:ENSGALP00000004750	intact:EBI-10686157	psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short)	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10821888|imex:IM-24146-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 1|comment:Alpha3 and beta4 subunits act as baits.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/20	rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rigid:0gvm3hX6xfrDe7XfWgTZ+yU8YA4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09481	uniprotkb:P26153	intact:EBI-10686191|ensembl:ENSGALP00000004750	intact:EBI-10686176	psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short)	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10821888|imex:IM-24146-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 1|comment:Alpha3 and beta4 subunits act as baits.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/20	rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rigid:0gvm3hX6xfrDe7XfWgTZ+yU8YA4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P26153	uniprotkb:P26152	intact:EBI-10686176	intact:EBI-10686157	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10824163|imex:IM-24146-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/26	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rigid:aBG6HAH8nt6s82hy2oKVEWmzoq8	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09484	uniprotkb:P26152	intact:EBI-10686072	intact:EBI-10686157	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10824169|imex:IM-24146-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/26	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rigid:OrAmi5nFzsWUnL3pjiGtw6pET5c	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09484	uniprotkb:P09481	intact:EBI-10686072	intact:EBI-10686191|ensembl:ENSGALP00000004750	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815365|imex:IM-24146-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/15	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031	rigid:DS2qFN4atwgvTIh2zFQQ/C2OR1M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09484	uniprotkb:P26152	intact:EBI-10686072	intact:EBI-10686157	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815365|imex:IM-24146-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/15	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rigid:DS2qFN4atwgvTIh2zFQQ/C2OR1M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09484	uniprotkb:P26153	intact:EBI-10686072	intact:EBI-10686176	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815365|imex:IM-24146-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/15	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rigid:DS2qFN4atwgvTIh2zFQQ/C2OR1M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26152	uniprotkb:P09481	intact:EBI-10686157	intact:EBI-10686191|ensembl:ENSGALP00000004750	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815371|imex:IM-24146-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594	-	-	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/15	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031	rigid:DS2qFN4atwgvTIh2zFQQ/C2OR1M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26152	uniprotkb:P09484	intact:EBI-10686157	intact:EBI-10686072	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815371|imex:IM-24146-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/15	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rigid:DS2qFN4atwgvTIh2zFQQ/C2OR1M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26152	uniprotkb:P26153	intact:EBI-10686157	intact:EBI-10686176	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815371|imex:IM-24146-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/15	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rigid:DS2qFN4atwgvTIh2zFQQ/C2OR1M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26152	uniprotkb:P26153	intact:EBI-10686157	intact:EBI-10686176	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815388|imex:IM-24146-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/05	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rigid:aBG6HAH8nt6s82hy2oKVEWmzoq8	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P26152	uniprotkb:P09484	intact:EBI-10686157	intact:EBI-10686072	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815394|imex:IM-24146-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 6a, 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/05	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rigid:OrAmi5nFzsWUnL3pjiGtw6pET5c	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09484	uniprotkb:P09481	intact:EBI-10686072	intact:EBI-10686191|ensembl:ENSGALP00000004750	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815419|imex:IM-24146-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/05	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031	rigid:L22ZJqfPDsM6OFUJmkshxzGgqao	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P09484	uniprotkb:P26152	intact:EBI-10686072	intact:EBI-10686157	psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym)	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815419|imex:IM-24146-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/05	rogid:W8PeYpMt64vzQGyNy39VgQbSd889031	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rigid:L22ZJqfPDsM6OFUJmkshxzGgqao	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P26153	uniprotkb:P09481	intact:EBI-10686176	intact:EBI-10686191|ensembl:ENSGALP00000004750	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815426|imex:IM-24146-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/05	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031	rigid:0gvm3hX6xfrDe7XfWgTZ+yU8YA4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P26153	uniprotkb:P26152	intact:EBI-10686176	intact:EBI-10686157	psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym)	psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815426|imex:IM-24146-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/05	rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031	rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031	rigid:0gvm3hX6xfrDe7XfWgTZ+yU8YA4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P60615	uniprotkb:P22770	intact:EBI-7516391|uniprotkb:Q9PRI6|uniprotkb:Q9YI07|uniprotkb:P01378|uniprotkb:Q9YGD1|uniprotkb:Q9YI11|uniprotkb:Q9YI06|intact:MINT-5223718|uniprotkb:Q9YI09|uniprotkb:Q9YI10|uniprotkb:Q9YI13|uniprotkb:Q9YI12	intact:EBI-10816017	psi-mi:3l21a_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym)|uniprotkb:Alpha-bungarotoxin, isoform A31(gene name synonym)|uniprotkb:Alpha-elapitoxin-Bm2a(gene name synonym)	psi-mi:acha7_chick(display_long)|uniprotkb:CHRNA7(gene name)|psi-mi:CHRNA7(display_short)	psi-mi:"MI:0892"(solid phase assay)	Conroy et al. (1995)	imex:IM-24146|pubmed:7876208	taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815406|imex:IM-24146-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P60615|interpro:IPR035076|interpro:IPR018354|interpro:IPR003571(Snake toxin)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1ABT|rcsb pdb:1BXP|rcsb pdb:1HAA|rcsb pdb:1HAJ|rcsb pdb:1HC9|rcsb pdb:1HOY|rcsb pdb:1IDG|rcsb pdb:1IDH|rcsb pdb:1IDI|rcsb pdb:1IDL|rcsb pdb:1IK8|rcsb pdb:1IKC|rcsb pdb:1JBD|rcsb pdb:1KC4|rcsb pdb:1KFH|rcsb pdb:1KL8|rcsb pdb:1L4W|rcsb pdb:1LJZ|rcsb pdb:1LK1|rcsb pdb:1RGJ|rcsb pdb:2ABX|rcsb pdb:2BTX|rcsb pdb:6UWZ	rcsb pdb:1KC4|rcsb pdb:1KL8|rcsb pdb:1OL3|rcsb pdb:1OL4|rcsb pdb:1OL8|rcsb pdb:1OL9|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035094"(response to nicotine)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043204"(perikaryon)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050890"(cognition)|interpro:IPR036719|interpro:IPR036734	-	comment:mint|function:"Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (alpha-7, alpha-8, and alpha-9) nicotinic acetylcholine receptors. Blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4.2 uM)"	-	figure legend:Fig. 6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2015/05/05	2015/05/06	rogid:H8HmrCO0Ummh3xuVj5FOUmoCcN08616	rogid:eWTQAcOerWpBN49D+uEQCILXcJI9031	rigid:8CWY/WFLnEz8ByrVYXg31lO6zGc	false	125i radiolabel:?-?	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)