#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q16649 intact:EBI-10092992 intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 - psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093008|imex:IM-23704-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 4|causality statement:Q16649 increases expression at RNA level of ENSG00000164399|comment:"An NF-IL3A-generated gel shift band was also observed in an EMSA with nuclear extracts from MLA144 T cells (Fig. 8), in which NF-IL3A was shown to increase the activity of IL3 promoter constructs; however, since no antibody was used to identify the participant, this experiment was not captured here."|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 - intact-crc:EF1634DF86A7CBE9 false - 32p radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093014|imex:IM-23704-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:92A6D59E01EE817E false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 intact:EBI-10092992 - - psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093014|imex:IM-23704-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 - - intact-crc:92A6D59E01EE817E false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093021|imex:IM-23704-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:BAA26C1184411F77 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 intact:EBI-10092995 - - psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:il3_human_-165/-128_dna-probe(display_short)|psi-mi:EBI-10092995(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093021|imex:IM-23704-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - - intact-crc:BAA26C1184411F77 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093036|imex:IM-23704-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:506E09FDEC209D46 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 intact:EBI-10093028 - - psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:ifng_human_par-site_dna-probe(display_short)|psi-mi:EBI-10093028(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093036|imex:IM-23704-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) ensembl:ENSG00000111537(see-also) - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 - - intact-crc:506E09FDEC209D46 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q16649 intact:EBI-10093072 intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 - psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093075|imex:IM-23704-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 - intact-crc:585528DB6B52021B false - 32p radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10093072 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093082|imex:IM-23704-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:F9CE9099EB176074 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10093072 intact:EBI-10093072 - - psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093082|imex:IM-23704-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - - intact-crc:F9CE9099EB176074 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10093072 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093089|imex:IM-23704-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:4160A017CDF1E972 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10093072 intact:EBI-10092992 - - psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093089|imex:IM-23704-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - - intact-crc:4160A017CDF1E972 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10093072 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093096|imex:IM-23704-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:66966D500774B500 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10093072 intact:EBI-10092995 - - psi-mi:il3_human_-149/-134_dna-probe(display_short)|psi-mi:EBI-10093072(display_long) psi-mi:il3_human_-165/-128_dna-probe(display_short)|psi-mi:EBI-10092995(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093096|imex:IM-23704-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 6|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 - - intact-crc:66966D500774B500 false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 uniprotkb:Q16649 - intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093140|imex:IM-23704-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164399(see-also) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 - rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 intact-crc:AB99B2946208778D false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-10092992 intact:EBI-10093137 - - psi-mi:il3_human_-160/-141_dna-probe(display_short)|psi-mi:EBI-10092992(display_long) psi-mi:e4_adenovirus_e4bp4-site_dna-probe(display_short)|psi-mi:EBI-10093137(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093140|imex:IM-23704-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000164399(see-also) - - - - figure legend:Fig. 4|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 - - intact-crc:AB99B2946208778D false 32p radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q16649 ensembl:ENSG00000164399 intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 intact:EBI-10093062 psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) uniprotkb:IL3(gene name)|psi-mi:IL3(display_short)|ensembl:il3_human_gene(shortlabel)|psi-mi:ENSG00000164399(display_long) psi-mi:"MI:0606"(DNase I footprinting) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093064|imex:IM-23704-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 refseq:NP_000579.2 - - - figure legend:Fig. 5|comment:The labeled DNA fragment used in this interaction corresponds to the IL3 gene promoter region ranging from -273 to -61.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2019/01/30 rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 - intact-crc:9515AB704F1088A2 false - 32p radiolabel:?-?|sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16649 intact:EBI-10092995 intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689 - psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym) psi-mi:il3_human_-165/-128_dna-probe(display_short)|psi-mi:EBI-10092995(display_long) psi-mi:"MI:0066"(lambda phage display) Zhang et al. (1995) pubmed:7565758|imex:IM-23704 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10093393|imex:IM-23704-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1 ensembl:ENSG00000164399(see-also) - - - figure legend:Fig. 1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/21 2015/01/21 rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606 - intact-crc:80294AD4BDABE584 false - 32p radiolabel:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)