#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q15311	uniprotkb:P11233	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-1036803|uniprotkb:A4D1W3|ensembl:ENSP00000005257	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:rala_human(display_long)|uniprotkb:RAL(gene name synonym)|uniprotkb:RALA(gene name)|psi-mi:RALA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jinesh et al. (2017)	imex:IM-24526|pubmed:28851898	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11179718	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149	refseq:NP_005393.2|refseq:XP_006715825.1|go:"GO:0019003"(GDP binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051665"(membrane raft localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:1UAD|rcsb pdb:1ZC3|rcsb pdb:1ZC4|rcsb pdb:2A78|mint:P11233|rcsb pdb:2A9K|rcsb pdb:2BOV|rcsb pdb:6P0I|rcsb pdb:6P0J|rcsb pdb:6P0K|rcsb pdb:6P0L|rcsb pdb:6P0M|rcsb pdb:6P0N|rcsb pdb:6P0O|reactome:R-HSA-1445148|reactome:R-HSA-171007|reactome:R-HSA-8950505|ensembl:ENSG00000006451(gene)|ensembl:ENST00000005257(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|refseq:XP_011513768.1	-	-	-	figure legend:6a, 6b, 6c|antagonist:"Verapamil (CHEBI:9948) and dasatinib (CHEBI:49375) reduced RalA activation and decreased the interaction of the bait with both preys. VEGF-A (P15692) increased RalA activation and its interaction with the bait, but reduced the amount of E-cadherin interacting."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-urinary_bladder_carcinoma)|taxid:9606(Human urinary bladder carcinoma)	-	2015/09/21	2017/09/05	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:41WF1UoYnYZvwC0OPpYwCEqIg2E9606	rigid:sOKr5Kdec6TGjMMA2b6yiomPfBM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15311	uniprotkb:P12830	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jinesh et al. (2017)	imex:IM-24526|pubmed:28851898	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11179718	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149	go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N	-	-	-	figure legend:6a, 6b, 6c|antagonist:"Verapamil (CHEBI:9948) and dasatinib (CHEBI:49375) reduced RalA activation and decreased the interaction of the bait with both preys. VEGF-A (P15692) increased RalA activation and its interaction with the bait, but reduced the amount of E-cadherin interacting."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-urinary_bladder_carcinoma)|taxid:9606(Human urinary bladder carcinoma)	-	2015/09/21	2017/09/05	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rigid:sOKr5Kdec6TGjMMA2b6yiomPfBM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11233	uniprotkb:Q15311	intact:EBI-1036803|uniprotkb:A4D1W3|ensembl:ENSP00000005257	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	psi-mi:rala_human(display_long)|uniprotkb:RAL(gene name synonym)|uniprotkb:RALA(gene name)|psi-mi:RALA(display_short)	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jinesh et al. (2017)	imex:IM-24526|pubmed:28851898	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16412049	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005393.2|refseq:XP_006715825.1|go:"GO:0019003"(GDP binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051665"(membrane raft localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:1UAD|rcsb pdb:1ZC3|rcsb pdb:1ZC4|rcsb pdb:2A78|mint:P11233|rcsb pdb:2A9K|rcsb pdb:2BOV|rcsb pdb:6P0I|rcsb pdb:6P0J|rcsb pdb:6P0K|rcsb pdb:6P0L|rcsb pdb:6P0M|rcsb pdb:6P0N|rcsb pdb:6P0O|reactome:R-HSA-1445148|reactome:R-HSA-171007|reactome:R-HSA-8950505|ensembl:ENSG00000006451(gene)|ensembl:ENST00000005257(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|refseq:XP_011513768.1	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149	-	-	-	figure legend:6a|antagonist:verapamil and dasatinib|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-urinary_bladder_carcinoma)|taxid:9606(Human urinary bladder carcinoma)	-	2015/09/21	2017/09/05	rogid:41WF1UoYnYZvwC0OPpYwCEqIg2E9606	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rigid:NrtWHcB+RSiByeGkyRDsbvvLdLU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11233	uniprotkb:Q15311	intact:EBI-1036803|uniprotkb:A4D1W3|ensembl:ENSP00000005257	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	psi-mi:rala_human(display_long)|uniprotkb:RAL(gene name synonym)|uniprotkb:RALA(gene name)|psi-mi:RALA(display_short)	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jinesh et al. (2017)	imex:IM-24526|pubmed:28851898	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16412066|imex:IM-24526-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005393.2|refseq:XP_006715825.1|go:"GO:0019003"(GDP binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051665"(membrane raft localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:1UAD|rcsb pdb:1ZC3|rcsb pdb:1ZC4|rcsb pdb:2A78|mint:P11233|rcsb pdb:2A9K|rcsb pdb:2BOV|rcsb pdb:6P0I|rcsb pdb:6P0J|rcsb pdb:6P0K|rcsb pdb:6P0L|rcsb pdb:6P0M|rcsb pdb:6P0N|rcsb pdb:6P0O|reactome:R-HSA-1445148|reactome:R-HSA-171007|reactome:R-HSA-8950505|ensembl:ENSG00000006451(gene)|ensembl:ENST00000005257(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|refseq:XP_011513768.1	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149	-	-	-	figure legend:6a|antagonist:verapamil and dasatinib|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-urinary_bladder_carcinoma)|taxid:9606(Human urinary bladder carcinoma)	-	2015/09/21	2017/09/05	rogid:41WF1UoYnYZvwC0OPpYwCEqIg2E9606	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rigid:NrtWHcB+RSiByeGkyRDsbvvLdLU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)