#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1247"(microscale thermophoresis) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11179444|imex:IM-23809-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:4a, 5a, 5b|comment:"The interaction was tested at different temperatures, showing inverse dependency: 30°C (0.3nM)>35°C (2.8nM)>37°C (16nM)>41°C (19nM). Analogously, different pHs were tested. The strongest binding was detected at a pH of 7 (EC50: 0.3 nM)."|kinetic_conditions:Unless otherwise stated, temp=30C, pH=7.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ec50:1.5x10^-9(molar) 2015/02/05 2015/09/18 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n|sufficient binding region:433-592 maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1247"(microscale thermophoresis) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11179457|imex:IM-23809-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:4b|kinetic_conditions:Temp=30C, pH=7|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ec50:1.6x10^-9(molar) 2015/02/05 2015/09/18 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n|sufficient binding region:433-942 maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1247"(microscale thermophoresis) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11179470|imex:IM-23809-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:4c|kinetic_conditions:Temp=30C, pH=7|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ec50:5.6x10^-9(molar) 2015/02/05 2015/09/18 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n|sufficient binding region:785-942 maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1247"(microscale thermophoresis) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11179483|imex:IM-23809-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:4d|kinetic_conditions:Temp=30C, pH=7|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ec50:33.7x10^-9(molar) 2015/02/05 2015/09/18 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n|sufficient binding region:56-237 maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1247"(microscale thermophoresis) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11179496|imex:IM-23809-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:4e|kinetic_conditions:Temp=30C, pH=7|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ec50:87.9x10^-9(molar) 2015/02/05 2015/09/18 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n|sufficient binding region:960-1204 maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:O90299 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179917|imex:IM-23809-6 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 34|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:21D650A6D1D0E0CF|rigid:txErP4rSAeVCZ2ZmjAlZf7PW4ck false activation domain tag:c-c dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:O90299 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179956|imex:IM-23809-9 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 34|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:DFDFE03C171A3EF4|rigid:txErP4rSAeVCZ2ZmjAlZf7PW4ck false dna binding domain tag:n-n activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:O90299 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179943|imex:IM-23809-8 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 34|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:02E78B453952A3CC|rigid:txErP4rSAeVCZ2ZmjAlZf7PW4ck false dna binding domain tag:n-n activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179969|imex:IM-23809-10 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 2|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:04335736EDA561C3|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:56-237|dna binding domain tag:c-c activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:O90299 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179930|imex:IM-23809-7 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 34|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:337D4BFF0FDAB30B|rigid:txErP4rSAeVCZ2ZmjAlZf7PW4ck false dna binding domain tag:c-c activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180029|imex:IM-23809-14 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 2|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:83DADEC8AF78E83B|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:56-237|dna binding domain tag:n-n activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180014|imex:IM-23809-13 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 23|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:10D891979F0687B2|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:785-942|dna binding domain tag:c-c activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179984|imex:IM-23809-11 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 23|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:78F8409B146C0FDF|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:785-942|dna binding domain tag:c-c activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11179999|imex:IM-23809-12 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 2|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:59946E8F813A67EB|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:c-c|sufficient binding region:56-237 activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180059|imex:IM-23809-16 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 9|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:C9D502DAFC6C89C5|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false activation domain tag:c-c sufficient binding region:433-592|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180044|imex:IM-23809-15 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 14|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:CFB404151446FC20|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:433-942|dna binding domain tag:n-n activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180089|imex:IM-23809-18 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 29|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:822B53E072F2B7A4|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:1207-1693|dna binding domain tag:n-n activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180074|imex:IM-23809-17 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 23|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:74D9F7BB851910B0|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:n-n|sufficient binding region:785-942 activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180104|imex:IM-23809-19 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 2|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:2AE2106AD1164C8F|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:n-n|sufficient binding region:56-237 activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180149|imex:IM-23809-22 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 23|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:06DE5A9DB1F32C51|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false activation domain tag:n-n sufficient binding region:785-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180134|imex:IM-23809-21 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 9|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:57021479EFF2A2E2|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:n-n|sufficient binding region:433-592 activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180164|imex:IM-23809-23 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 25|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:3742EEA144975E04|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:960-1204|dna binding domain tag:n-n activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180119|imex:IM-23809-20 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 14|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:CBD15A2AD52422C6|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false activation domain tag:n-n sufficient binding region:433-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180179|imex:IM-23809-24 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 29|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:54E5BE35191F8019|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false activation domain tag:n-n sufficient binding region:1207-1693|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180194|imex:IM-23809-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:595FA70E910E0F90|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false activation domain tag:c-c|sufficient binding region:118-313 sufficient binding region:118-660|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180242|imex:IM-23809-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 13|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:F22007A2496CCE6E|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false dna binding domain tag:c-c|sufficient binding region:314-660 sufficient binding region:314-660|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180227|imex:IM-23809-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 9|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:C62778EB7ACACD72|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:118-313|activation domain tag:c-c sufficient binding region:314-453|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180212|imex:IM-23809-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:C9C28ED5FD9780F0|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false activation domain tag:c-c|sufficient binding region:314-660 sufficient binding region:118-660|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180272|imex:IM-23809-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 18|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:F87A5A5605DA8FBE|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:454-660|dna binding domain tag:c-c sufficient binding region:454-660|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180257|imex:IM-23809-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 19|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:DC7ACEBCA4CE5675|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:454-660|dna binding domain tag:c-c sufficient binding region:118-313|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180302|imex:IM-23809-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:1DCDDCBBB3F4FBD9|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:118-453|activation domain tag:n-n sufficient binding region:118-660|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180287|imex:IM-23809-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 22|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:E42BCA65D2F7700B|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:118-313|activation domain tag:n-n sufficient binding region:118-453|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180377|imex:IM-23809-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 7|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:86C1DCE6A0D475F8|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false activation domain tag:n-n|sufficient binding region:314-453 dna binding domain tag:c-c|sufficient binding region:314-453 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180362|imex:IM-23809-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 12|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:D3D2501E05C32AF7|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:314-453|activation domain tag:n-n sufficient binding region:314-660|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180317|imex:IM-23809-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 20|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:C0682BEBB930B988|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:118-453|dna binding domain tag:c-c activation domain tag:n-n|sufficient binding region:314-453 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180347|imex:IM-23809-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 9|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:1D7C521D5C7D7C89|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:314-453|dna binding domain tag:c-c sufficient binding region:118-313|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180332|imex:IM-23809-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:45CAEDD1B8D7BA15|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false dna binding domain tag:c-c|sufficient binding region:118-660 sufficient binding region:454-660|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180392|imex:IM-23809-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 19|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:5FA47FAD9137CBD0|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:118-313|activation domain tag:n-n sufficient binding region:454-660|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180422|imex:IM-23809-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 22|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:D45311C2827B9CB2|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false activation domain tag:c-c|sufficient binding region:118-313 dna binding domain tag:n-n|sufficient binding region:118-453 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180437|imex:IM-23809-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:E5700F5E6A3CDFA2|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false activation domain tag:c-c|sufficient binding region:118-313 dna binding domain tag:n-n|sufficient binding region:118-660 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180452|imex:IM-23809-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 20|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:B5D5205DFA6CAC92|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:118-453|dna binding domain tag:n-n sufficient binding region:314-453|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180407|imex:IM-23809-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 18|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:5A532323CE915F6C|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false activation domain tag:n-n|sufficient binding region:454-660 sufficient binding region:454-660|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180527|imex:IM-23809-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 18|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:6017AB2996000A78|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:454-660|dna binding domain tag:n-n activation domain tag:n-n|sufficient binding region:454-660 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180467|imex:IM-23809-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 10|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:41CDA244FCBEAED9|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false dna binding domain tag:n-n|sufficient binding region:314-453 activation domain tag:c-c|sufficient binding region:118-453 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180497|imex:IM-23809-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 7|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:8E6D5C8F328403E8|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:314-453|dna binding domain tag:n-n activation domain tag:c-c|sufficient binding region:314-453 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180482|imex:IM-23809-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 12|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:5222E55D3B7D0B89|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:314-660|dna binding domain tag:n-n sufficient binding region:314-453|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180512|imex:IM-23809-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, fig. 2b|comment:Table 3 - 17|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:99511884F241562F|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false sufficient binding region:314-660|activation domain tag:c-c sufficient binding region:454-660|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180557|imex:IM-23809-49 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 32|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:A96D1D1E580B96E5|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:c-c activation domain tag:c-c|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180587|imex:IM-23809-51 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 33|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:6686D7AE1F34D295|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:c-c activation domain tag:n-n|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180572|imex:IM-23809-50 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 31|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:095769914DA0A427|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:c-c activation domain tag:n-n|sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180542|imex:IM-23809-48 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 33|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:B3417B8C4395BF5B|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false activation domain tag:c-c|sufficient binding region:433-942 dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q9WC28 intact:EBI-11180197 intact:EBI-11179420|uniprotkb:O39221 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180662|imex:IM-23809-56 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 35|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:909B688BE21443EB|rigid:8wbPEAmge1WsVGsl1luBag+Rqg0 false dna binding domain tag:n-n sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180647|imex:IM-23809-55 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 32|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:5368F463CE79061C|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:n-n sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180632|imex:IM-23809-54 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 33|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:EE592438A911672B|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:433-942|activation domain tag:n-n dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180602|imex:IM-23809-52 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 32|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:610F2F6DBDBEBCE0|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:c-c sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180617|imex:IM-23809-53 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 32|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:B2AC9F12AD82542B|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false dna binding domain tag:n-n sufficient binding region:785-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180677|imex:IM-23809-57 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 1|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:A54596B7D6F5C248|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:c-c|sufficient binding region:56-237 sufficient binding region:785-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180694|imex:IM-23809-58 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 11|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:598BE5304CAE27EE|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|dna binding domain tag:c-c sufficient binding region:433-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180745|imex:IM-23809-61 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 20|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:AEDE0D82A838C8C0|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:c-c|sufficient binding region:785-942 activation domain tag:c-c|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180728|imex:IM-23809-60 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 18|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:5075E014212A87E3|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237|activation domain tag:c-c sufficient binding region:785-942|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180711|imex:IM-23809-59 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 6|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:3050E97C9BEBA854|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|activation domain tag:c-c sufficient binding region:433-592|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180796|imex:IM-23809-64 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 1|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:F7F8C2E6884E0896|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|activation domain tag:n-n sufficient binding region:56-237|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180779|imex:IM-23809-63 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 4|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:2C7AAEB1BBBFAD0B|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237|dna binding domain tag:c-c activation domain tag:n-n|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180762|imex:IM-23809-62 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 3|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:B93E86BA28115008|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|activation domain tag:n-n sufficient binding region:56-237|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180813|imex:IM-23809-65 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 10|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:36488041CA9696B4|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|dna binding domain tag:c-c activation domain tag:n-n|sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180830|imex:IM-23809-66 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 11|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:CC68B3E8EEE5F7FE|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|activation domain tag:n-n sufficient binding region:433-942|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180864|imex:IM-23809-68 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 8|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:782DBDF32C81B453|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|activation domain tag:n-n sufficient binding region:433-592|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180881|imex:IM-23809-69 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 15|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1ED1837B8EF1371E|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:712-778 sufficient binding region:433-942|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180898|imex:IM-23809-70 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 17|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:5078AE7DDA80C5EA|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:c-c|sufficient binding region:712-778 activation domain tag:n-n|sufficient binding region:712-778 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180847|imex:IM-23809-67 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 6|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:2DB7739BD1A55E32|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|dna binding domain tag:c-c sufficient binding region:433-592|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180932|imex:IM-23809-72 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 19|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:93E72A72468422AC|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|activation domain tag:n-n dna binding domain tag:c-c|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180915|imex:IM-23809-71 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 18|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:4377CDF9112574DC|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:c-c|sufficient binding region:785-942 sufficient binding region:56-237|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180949|imex:IM-23809-73 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 21|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:133D7D014E084DBE|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:433-942 sufficient binding region:785-942|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181017|imex:IM-23809-77 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 1|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:A5FE08C7ECD786BD|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:56-237 activation domain tag:c-c|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180983|imex:IM-23809-75 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 22|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:6AFE07562A978111|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:960-1204 sufficient binding region:785-942|dna binding domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11180966|imex:IM-23809-74 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 20|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:389EB1FDADCD979C|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|activation domain tag:n-n dna binding domain tag:c-c|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181000|imex:IM-23809-76 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 30|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:FF7441EC3751F18A|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:1207-1693 dna binding domain tag:c-c|sufficient binding region:1207-1693 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181034|imex:IM-23809-78 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 12|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:9AFCE68ACB784D07|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237|activation domain tag:c-c sufficient binding region:433-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181051|imex:IM-23809-79 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 10|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:41DA2A9983A1F8C6|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|dna binding domain tag:n-n sufficient binding region:433-592|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181085|imex:IM-23809-81 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 6|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:96BDF633C409B091|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|activation domain tag:c-c dna binding domain tag:n-n|sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181068|imex:IM-23809-80 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 11|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:3A6A34EE1E944F27|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|dna binding domain tag:n-n sufficient binding region:433-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181119|imex:IM-23809-83 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 13|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:960287E07E4691BE|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:433-942 sufficient binding region:785-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181153|imex:IM-23809-85 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 17|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:B9226C0719A07B01|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:712-778|dna binding domain tag:n-n sufficient binding region:712-778|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181136|imex:IM-23809-84 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 7|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:809D61767F2429E6|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:433-592 sufficient binding region:785-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181102|imex:IM-23809-82 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 8|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:905B88BE2924713A|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:433-592 activation domain tag:c-c|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181221|imex:IM-23809-89 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 24|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:D373F9FEF28B0186|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:c-c|sufficient binding region:785-942 dna binding domain tag:n-n|sufficient binding region:960-1204 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181204|imex:IM-23809-88 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 20|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:465CDA702AEE68CB|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|dna binding domain tag:n-n sufficient binding region:785-942|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181238|imex:IM-23809-90 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 28|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:4B2C5722E146714C|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:c-c|sufficient binding region:433-942 sufficient binding region:1207-1693|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181187|imex:IM-23809-87 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 21|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:01F45FD82663E23D|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|dna binding domain tag:n-n activation domain tag:c-c|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181170|imex:IM-23809-86 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 18|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:C902360BFE4C6D1B|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:785-942 sufficient binding region:56-237|activation domain tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181255|imex:IM-23809-91 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 27|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:A8DB42F34E8E7826|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|activation domain tag:c-c sufficient binding region:1207-1693|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181272|imex:IM-23809-92 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 30|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1366A0F7F53B3C79|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:1207-1693|activation domain tag:c-c sufficient binding region:1207-1693|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181306|imex:IM-23809-94 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 4|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1F21F8A88D5E0C03|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:433-942 dna binding domain tag:n-n|sufficient binding region:56-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181289|imex:IM-23809-93 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 3|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:5FAAAF187005EC61|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|activation domain tag:n-n sufficient binding region:56-237|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181323|imex:IM-23809-95 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 1|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:37C682188A16CB53|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237|dna binding domain tag:n-n sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181340|imex:IM-23809-96 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 5|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:09DB77BA511A63AC|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:219-432 sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181357|imex:IM-23809-97 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 12|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:115D244A65C64A3B|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:433-942 activation domain tag:n-n|sufficient binding region:56-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181391|imex:IM-23809-99 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 11|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:5DF0A07FFD0B7911|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:433-942 sufficient binding region:433-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181374|imex:IM-23809-98 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 10|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:9151B913F7B824C9|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|dna binding domain tag:n-n activation domain tag:n-n|sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181425|imex:IM-23809-101 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 8|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:C889A17566ABE0F9|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:433-592 activation domain tag:n-n|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181408|imex:IM-23809-100 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 6|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:ADB1A0F9A429602C|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|dna binding domain tag:n-n activation domain tag:n-n|sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181459|imex:IM-23809-103 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 7|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:80D8237AE171AFA8|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false activation domain tag:n-n|sufficient binding region:785-942 sufficient binding region:433-592|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181476|imex:IM-23809-104 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 16|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:54D84A152BA46876|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|dna binding domain tag:n-n activation domain tag:n-n|sufficient binding region:1207-1693 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181493|imex:IM-23809-105 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 18|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:361938CCCAE812A0|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237|activation domain tag:n-n sufficient binding region:785-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181442|imex:IM-23809-102 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 13|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:B69F5791C3BD22C9|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|activation domain tag:n-n sufficient binding region:433-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181544|imex:IM-23809-108 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 20|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:9A95905957B56359|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false dna binding domain tag:n-n|sufficient binding region:785-942 sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181510|imex:IM-23809-106 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 19|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:D8E59257EBFB8895|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|dna binding domain tag:n-n sufficient binding region:433-592|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181527|imex:IM-23809-107 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 21|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:842629B7BA5898BC|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|activation domain tag:n-n sufficient binding region:785-942|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181595|imex:IM-23809-111 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 26|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:DDFBE4E7E55A7AFF|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|activation domain tag:n-n sufficient binding region:1207-1693|dna binding domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181612|imex:IM-23809-112 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 28|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:B55102397451035B|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:1207-1693|dna binding domain tag:n-n activation domain tag:n-n|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181578|imex:IM-23809-110 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 24|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:54154C2818FD720B|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:960-1204|dna binding domain tag:n-n activation domain tag:n-n|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181561|imex:IM-23809-109 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 22|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1625D430FF175471|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|dna binding domain tag:n-n sufficient binding region:960-1204|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0018"(two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181629|imex:IM-23809-113 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 27|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:B48CFE0F6409FD38|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:1207-1693|dna binding domain tag:n-n sufficient binding region:785-942|activation domain tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:O90299 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181648|imex:IM-23809-114 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 34|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:C14BBCB0D1D115D7|rigid:txErP4rSAeVCZ2ZmjAlZf7PW4ck false tandem tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:O90299 intact:EBI-11180197 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181661|imex:IM-23809-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Figs. 3 and 2b|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:D3F65D89CF417718|rigid:k3AlnXJ46hbZn7Hv8gkzvGMcg/s false maltose binding protein tag:n-n tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181671|imex:IM-23809-116 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 2|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:11C406F4EDF30AA7|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n|sufficient binding region:56-237 tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181686|imex:IM-23809-117 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 14|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:65EC4FDCAC408786|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:433-942|maltose binding protein tag:n-n tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181701|imex:IM-23809-118 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 9|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:F7834C3798E00D2E|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false tandem tag:n-n maltose binding protein tag:n-n|sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181746|imex:IM-23809-121 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 29|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:671EAFBD48DE9C3F|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false tandem tag:n-n sufficient binding region:1207-1693|maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181716|imex:IM-23809-119 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 23|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:70AD81AAF662FC02|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:785-942|maltose binding protein tag:n-n tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181731|imex:IM-23809-120 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 25|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:0E1F61302F2E7D48|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false tandem tag:n-n sufficient binding region:960-1204|maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181775|imex:IM-23809-123 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 31|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:D28ABAD29F3AB85E|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false maltose binding protein tag:n-n sufficient binding region:433-592|tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181790|imex:IM-23809-124 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 33|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:6F336A10CEDE48E5|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false tandem tag:n-n|sufficient binding region:433-942 maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q68985 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11180197 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181805|imex:IM-23809-125 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 35|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:19BF1A77EA6946A9|rigid:8wbPEAmge1WsVGsl1luBag+Rqg0 false sufficient binding region:785-942|tandem tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68985 uniprotkb:Q68985 intact:EBI-11180197 intact:EBI-11180197 psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:capsd_hevhy(display_long)|uniprotkb:Protein ORF2(gene name synonym)|uniprotkb:ORF2(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181761|imex:IM-23809-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 interpro:IPR004261(Hepatitis E virus structural protein 2)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039615"(T=1 icosahedral viral capsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044228"(host cell surface)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|interpro:IPR029053 - - - figure legend:Table 3, figs. 3 and 2b|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 rogid:wOJWpE/EBsA3nYK3qFFg2Shq+9Q512346 intact-crc:B5E0FED46F270055|rigid:OmSlFVwgy8QklYHoG0lzp+RBup0 false tandem tag:n-n|sufficient binding region:118-660 maltose binding protein tag:n-n|sufficient binding region:118-660 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181854|imex:IM-23809-128 author score:medium - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 5|author-confidence:medium|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:54D28C1170788599|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:219-432|maltose binding protein tag:n-n sufficient binding region:785-942|tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181837|imex:IM-23809-127 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 1|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1B677D3DEAA9A529|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false maltose binding protein tag:n-n|sufficient binding region:56-237 tandem tag:n-n|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181820|imex:IM-23809-126 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 4|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:ED7E882C5B1CCB83|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|tandem tag:n-n maltose binding protein tag:n-n|sufficient binding region:56-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181905|imex:IM-23809-131 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 11|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:51BB4C326EE28598|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|tandem tag:n-n maltose binding protein tag:n-n|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181888|imex:IM-23809-130 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 10|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:DD2DEF12517AF9AE|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false tandem tag:n-n|sufficient binding region:433-592 sufficient binding region:433-942|maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181871|imex:IM-23809-129 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 12|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:BC066E697085A288|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942|maltose binding protein tag:n-n tandem tag:n-n|sufficient binding region:56-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181922|imex:IM-23809-132 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 6|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:816BACD3BF29E6B2|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|maltose binding protein tag:n-n sufficient binding region:433-592|tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181939|imex:IM-23809-133 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 8|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:4A1221652BDAD3DB|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592|maltose binding protein tag:n-n tandem tag:n-n|sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181956|imex:IM-23809-134 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 13|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:8D62ABA4C3EF82AC|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942|tandem tag:n-n sufficient binding region:433-942|maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182007|imex:IM-23809-137 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 20|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:28EE444550C939F0|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false tandem tag:n-n|sufficient binding region:785-942 sufficient binding region:785-942|maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181990|imex:IM-23809-136 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 21|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:FBEFFE41D1891325|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false maltose binding protein tag:n-n|sufficient binding region:785-942 sufficient binding region:433-942|tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11181973|imex:IM-23809-135 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 16|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:E73B0554ED49CC9E|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false maltose binding protein tag:n-n|sufficient binding region:433-942 sufficient binding region:1207-1693|tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182041|imex:IM-23809-139 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 24|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:34B77909E77E7B9A|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false tandem tag:n-n|sufficient binding region:785-942 sufficient binding region:960-1204|maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182058|imex:IM-23809-140 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 28|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:27836D56941B1D80|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false maltose binding protein tag:n-n|sufficient binding region:1207-1693 sufficient binding region:433-942|tandem tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182024|imex:IM-23809-138 author score:high - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 22|author-confidence:high|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:0E1F39AAFA91E7E5|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false tandem tag:n-n|sufficient binding region:960-1204 maltose binding protein tag:n-n|sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:O90299 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182148|imex:IM-23809-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 34|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:C471864BBD7E2C00|rigid:txErP4rSAeVCZ2ZmjAlZf7PW4ck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182155|imex:IM-23809-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:4E392F679972D3C7|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false - sufficient binding region:56-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182182|imex:IM-23809-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 29|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:EF84821514CBED95|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false - sufficient binding region:1207-1693 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182173|imex:IM-23809-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 14,33|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:3F0465C606B25882|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false - sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:O90299 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179411|uniprotkb:Q68984 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182164|imex:IM-23809-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 23,32|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 intact-crc:363DB4339C384A55|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false sufficient binding region:785-942 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O90299 uniprotkb:Q9WC28 intact:EBI-11179411|uniprotkb:Q68984 intact:EBI-11179420|uniprotkb:O39221 psi-mi:orf3_hevhy(display_long)|uniprotkb:ORF3(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182191|imex:IM-23809-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003384(Hepatitis E virus ORF-2 capsid protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0044167"(host cell endoplasmic reticulum membrane) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 31,9|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:0kxz9JJwdDLCocD7ulEl3P734uI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:E871F8E2E5D9B1C4|rigid:lprARfPRNO6e8DerwwdxgE5+h4g false - sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182200|imex:IM-23809-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 1,18|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:4D4E4703B680A77D|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237 sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182222|imex:IM-23809-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:793F938CD54BB37F|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592 sufficient binding region:433-592 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182233|imex:IM-23809-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 20|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1970D1C59182DDBC|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942 sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182244|imex:IM-23809-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 4,12|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:A2B79EF7016DC6EA|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:56-237 sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182211|imex:IM-23809-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 11|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:3C5ABA80D6A7396F|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942 sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182266|imex:IM-23809-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 13,21|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:A6701679BD4521F3|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-942 sufficient binding region:785-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182277|imex:IM-23809-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 22, 24|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:2BDCA7832BBD19AD|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:785-942 sufficient binding region:960-1204 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182288|imex:IM-23809-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 16,28|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:BB0986F3F44CEFA9|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:1207-1693 sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WC28 uniprotkb:Q9WC28 intact:EBI-11179420|uniprotkb:O39221 intact:EBI-11179420|uniprotkb:O39221 psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:poln_hevhy(display_long)|uniprotkb:ORF1(orf name) psi-mi:"MI:1356"(validated two hybrid) Osterman et al. (2014) pubmed:26463011|imex:IM-23809 taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) taxid:512346(isolate Human/India/Hyderabad)|taxid:512346(Hepatitis E virus genotype 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11182255|imex:IM-23809-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 interpro:IPR044371|interpro:IPR027351|interpro:IPR002588(Viral methyltransferase)|interpro:IPR008748(Peptidase C41, hepatitis E ORF1)|interpro:IPR022202|interpro:IPR002589(Appr-1-p processing)|interpro:IPR027417|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR001788(RNA-dependent RNA polymerase, viral-type)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0008174"(mRNA methyltransferase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|interpro:IPR043472|interpro:IPR043502 - - - figure legend:Table 2, figs. 3 and 2b|comment:Table 2 - 8,10|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/02/05 2015/09/22 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 rogid:PD4XLE1liPNsR3CKD2i7/p2usuI512346 intact-crc:1EEFA5D15E392B2D|rigid:DcAvLlr5PxkJGubPLLiBl4wF8hY false sufficient binding region:433-592 sufficient binding region:433-942 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)