#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13422	uniprotkb:Q96SW2	intact:EBI-745305|uniprotkb:O00598|uniprotkb:Q8WVA3|uniprotkb:Q53XL2|uniprotkb:B4E0Z1|uniprotkb:A4D260|uniprotkb:D3DVM5|intact:EBI-28969803|ensembl:ENSP00000331614|uniprotkb:Q69BM4	intact:EBI-2510250|ensembl:ENSP00000231948|uniprotkb:B2R6H4|uniprotkb:C9IZA9|uniprotkb:C9JAH6|uniprotkb:Q6NVZ0|uniprotkb:Q6AI62|uniprotkb:Q9UHW4	psi-mi:ikzf1_human(display_long)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:crbn_human(display_long)|uniprotkb:CRBN(gene name)|psi-mi:CRBN(display_short)|uniprotkb:AD-006(orf name)	psi-mi:"MI:0096"(pull down)	Liu et al. (2015)	imex:IM-24529|pubmed:26183205	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11189384|imex:IM-24529-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001207694.1|refseq:NP_001207696.1|refseq:NP_001207697.1|refseq:NP_001207699.1|refseq:NP_001207700.1|refseq:NP_006051.1|refseq:NP_001278766.1|refseq:NP_001278767.1|refseq:NP_001278768.1|refseq:NP_001278769.1|refseq:NP_001278770.1|refseq:NP_001278771.1|refseq:NP_001278772.1|refseq:NP_001278773.1|ensembl:ENSP00000331614|ensembl:ENST00000343574|ensembl:ENSP00000342750|ensembl:ENST00000349824|ensembl:ENSP00000342485|ensembl:ENST00000357364|ensembl:ENSP00000349928|ensembl:ENST00000359197|ensembl:ENSP00000352123|ensembl:ENST00000438033|ensembl:ENSP00000396554|ensembl:ENST00000439701|ensembl:ENSP00000413025|ensembl:ENST00000331340(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007498"(mesoderm development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q13422|rcsb pdb:6H0F|reactome:R-HSA-9013508|ensembl:ENSG00000185811(gene)|refseq:XP_011513370.1|refseq:XP_011513371.1|refseq:XP_011513377.1|refseq:XP_011513378.1|refseq:XP_016867157.1|dip:DIP-41110N	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902607"(negative regulation of large conductance calcium-activated potassium channel activity)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034750|mint:Q96SW2|rcsb pdb:4M91|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5V3O|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|interpro:IPR015947(PUA-like)|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7BQU|rcsb pdb:7BQV|rcsb pdb:7LPS|reactome:R-HSA-9679191|ensembl:ENSG00000113851(gene)|ensembl:ENST00000231948(transcript)|refseq:NP_057386.2|refseq:NP_001166953.1|dip:DIP-53521N	-	-	-	figure legend:f3a|comment:"We  coexpressed FLAG-IKZF1 with Strep-CRBN in HEK293T cells and  treated the cells with lenalidomide, DRB, and Rosc along with a  proteasome inhibitor MG132. We then used Strep-Tactin agarose  beads to affinity-purify Strep-CRBN and its interacting proteins  and blotted the purified samples with anti-FLAG and anti-CRBN  antibodies. Immunoblotting results showed that IKZF1 was readily  detected in the pulldown when the cells were treated with  lenalidomide (Fig. 3A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/09/23	2015/09/23	rogid:RizH0uz3DbSyFFvmlIhisx+S+DI9606	rogid:R1sZch07ti/kUKYBByte0xAoCMo9606	rigid:Ae6DJm33KZJV2Vl6m/5VEbDEBVM	false	flag tag:?-?	strep tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)