#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-11422183 uniprotkb:Q63943 - intact:EBI-645322|uniprotkb:E9QKS9|uniprotkb:Q63944|ensembl:ENSMUSP00000103184 psi-mi:mef2_binding_consensus_ site_probe(display_short)|psi-mi:EBI-11422183(display_long) psi-mi:mef2d_mouse(display_long)|uniprotkb:Mef2d(gene name)|psi-mi:Mef2d(display_short) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Yang et al. (2014) imex:IM-24735|pubmed:25890150 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11422180|imex:IM-24735-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:XP_006501152.1|refseq:NP_001297516.1|refseq:XP_017174961.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q63943|reactome:R-MMU-525793|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000001419(gene)|ensembl:ENSMUST00000107559(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:2C|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/10/19 2015/11/23 - rogid:aOqrCwCEMvYQcHdMVQHmY7xRTnk10090 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) ensembl:ENSMUSG00000016529 uniprotkb:Q63943 intact:EBI-6398833 intact:EBI-645322|uniprotkb:E9QKS9|uniprotkb:Q63944|ensembl:ENSMUSP00000103184 psi-mi:il10_mouse_gene(display_short)|psi-mi:ENSMUSG00000016529(display_long) psi-mi:mef2d_mouse(display_long)|uniprotkb:Mef2d(gene name)|psi-mi:Mef2d(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yang et al. (2014) imex:IM-24735|pubmed:25890150 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11422198|imex:IM-24735-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006501152.1|refseq:NP_001297516.1|refseq:XP_017174961.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q63943|reactome:R-MMU-525793|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000001419(gene)|ensembl:ENSMUST00000107559(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:3 D|agonist:"CHEBI:16412 (LPS)"|causality statement:"CHEBI:16412 increases the binding of Q63943 to ENSMUSG00000016529"|causality statement:"CHEBI:16412 increases the expression at protein level of Q63943"|causality statement:"CHEBI:16412 increases the expression at RNA level of ENSMUSG00000016529"|causality statement:Q63943 increases the expression at RNA level of ENSMUSG00000016529|causality statement:Q63943 increases the expression at protein level of ENSMUSG00000016529|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells) - 2015/10/19 2015/11/23 - rogid:aOqrCwCEMvYQcHdMVQHmY7xRTnk10090 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSMUSG00000016529 uniprotkb:Q63943 intact:EBI-6398833 intact:EBI-645322|uniprotkb:E9QKS9|uniprotkb:Q63944|ensembl:ENSMUSP00000103184 psi-mi:il10_mouse_gene(display_short)|psi-mi:ENSMUSG00000016529(display_long) psi-mi:mef2d_mouse(display_long)|uniprotkb:Mef2d(gene name)|psi-mi:Mef2d(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yang et al. (2014) imex:IM-24735|pubmed:25890150 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12595277|imex:IM-24735-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006501152.1|refseq:NP_001297516.1|refseq:XP_017174961.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q63943|reactome:R-MMU-525793|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000001419(gene)|ensembl:ENSMUST00000107559(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:3 C|agonist:"CHEBI:16412 (LPS)"|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bv2)|taxid:10090(Mouse BV2 glioma cells) - 2015/10/19 2016/11/08 - rogid:aOqrCwCEMvYQcHdMVQHmY7xRTnk10090 - false sufficient binding region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr)