#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43236 uniprotkb:Q8IYM1 intact:EBI-1047513|uniprotkb:Q9UM58|uniprotkb:Q6IAP3|uniprotkb:B2RD42|uniprotkb:B3KSX9|uniprotkb:B4DXC6|uniprotkb:B4DXV5|uniprotkb:Q9H315|ensembl:ENSP00000321674|uniprotkb:A0A5F9ZHH3|uniprotkb:Q8N821|uniprotkb:Q8NEP4|intact:EBI-25939820|intact:EBI-13336111 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept4_human(display_long)|uniprotkb:SEPTIN4(gene name)|psi-mi:SEPTIN4(display_short)|uniprotkb:ARTS(gene name synonym)|uniprotkb:Apoptosis-related protein in the TGF-beta signaling pathway(gene name synonym)|uniprotkb:Bradeion beta(gene name synonym)|uniprotkb:Brain protein H5(gene name synonym)|uniprotkb:CE5B3 beta(gene name synonym)|uniprotkb:Cell division control-related protein 2(gene name synonym)|uniprotkb:Cerebral protein 7(gene name synonym)|uniprotkb:PNUTL2(gene name synonym)|uniprotkb:Peanut-like protein 2(gene name synonym)|uniprotkb:SEP4(gene name synonym)|uniprotkb:SEPT4(gene name synonym)|uniprotkb:hucep-7(orf name)|uniprotkb:C17orf47(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819409|imex:IM-24270-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011523213.1|refseq:XP_011523214.1|refseq:NP_001185642.1|refseq:NP_004565.1|refseq:NP_536341.1|refseq:NP_536340.1|refseq:NP_001033793.2|refseq:NP_001243711.1|refseq:NP_001243751.1|ensembl:ENSG00000108387(gene)|interpro:IPR027417|interpro:IPR030379|mint:O43236|rcsb pdb:6WB3|reactome:R-HSA-111457|reactome:R-HSA-111469|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENST00000317268(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0001764"(neuron migration)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0005198"(structural molecule activity)|go:"GO:0031105"(septin complex)|go:"GO:0005525"(GTP binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR016491(Septin)|refseq:XP_006722017.1|refseq:XP_006722018.1 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/13 rogid:bS5LZDK5bxr0WEZsE35enupzNQs9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:F+EctJgGKKvMATjbk1mNPCJjFzg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04554 uniprotkb:Q8IYM1 intact:EBI-9681663|uniprotkb:Q6ZMM0|ensembl:ENSP00000241808 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:prm2_human(display_long)|uniprotkb:PRM2(gene name)|psi-mi:PRM2(display_short)|uniprotkb:Sperm histone P2(gene name synonym)|uniprotkb:Sperm protamine P2(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819429|imex:IM-24270-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273285.1|refseq:NP_001273287.1|refseq:NP_001273288.1|refseq:NP_002753.2|ensembl:ENSG00000122304(gene)|ensembl:ENST00000241808(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006323"(DNA packaging)|go:"GO:0006997"(nucleus organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0046870"(cadmium ion binding)|interpro:IPR000492(Protamine 2, PRM2)|rcsb pdb:2AWR refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/13 rogid:zm0eyRyFa26Q3DV0e0WDJb6fdQ89606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:TIk6J5AuMQjUj/J75oHw5rHlCO4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BTX1 uniprotkb:Q8IYM1 intact:EBI-2552800|ensembl:ENSP00000360483|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819461|imex:IM-24270-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162023.1|refseq:NP_060557.3|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-170822|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|ensembl:ENSG00000058804(gene)|ensembl:ENST00000371429(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/13 rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:39nZ/2yOZZ8EysdZsMUYXpRsb3Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15154 uniprotkb:Q8IYM1 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819468|imex:IM-24270-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2018/04/06 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:oqJQrLfWqkVSiv8s+i6+bpB4DDY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75147 uniprotkb:Q8IYM1 intact:EBI-1223896|uniprotkb:A4KVA5|uniprotkb:Q96IW3|intact:EBI-7903201|intact:MINT-8415345|uniprotkb:A4KVA4|uniprotkb:S4R3M6|intact:EBI-28983679|ensembl:ENSP00000385636|uniprotkb:A0A024R468 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:obsl1_human(display_long)|uniprotkb:OBSL1(gene name)|psi-mi:OBSL1(display_short)|uniprotkb:KIAA0657(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819473|imex:IM-24270-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001166879.1|refseq:NP_056126.1|refseq:NP_001166902.1|ensembl:ENST00000373873|ensembl:ENSP00000362980|ensembl:ENSP00000385636|ensembl:ENST00000603926|ensembl:ENSP00000474519|dip:DIP-38340N|ensembl:ENSG00000124006(gene)|ensembl:ENST00000404537(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010842"(retina layer formation)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:1990393"(3M complex)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:O75147|rcsb pdb:2CPC|rcsb pdb:2E6P|rcsb pdb:2E6Q|rcsb pdb:2LU7|rcsb pdb:2LVC|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:3KNB|rcsb pdb:5FM5|reactome:R-HSA-8951664 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/13 rogid:HFxqB+AxsXH/zWXgCj/ODfSmqQQ9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:06jigXW+GAT7LaMr1JmGgOZk4Bg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14141 uniprotkb:Q8IYM1 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819483|imex:IM-24270-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/13 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:fh0B7vzVkq+giBNXe3VL1MJsKUo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NPE6 uniprotkb:Q8IYM1 intact:EBI-10819434|uniprotkb:O43648|ensembl:ENSP00000363391 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:spag4_human(display_long)|uniprotkb:SPAG4(gene name)|psi-mi:SPAG4(display_short)|uniprotkb:SUN4(gene name synonym)|uniprotkb:Outer dense fiber-associated protein SPAG4(gene name synonym)|uniprotkb:SUN domain-containing protein 4(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10819487|imex:IM-24270-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003107.1|ensembl:ENSG00000061656(gene)|ensembl:ENST00000374273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR027776 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/13 rogid:mc3+VLMGxLPQFQFJiVsoR+oizfk9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:8hn4g/ai79kN8ochN3fW9+oeg4w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYM1 uniprotkb:Q9NPE6 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-10819434|uniprotkb:O43648|ensembl:ENSP00000363391 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:spag4_human(display_long)|uniprotkb:SPAG4(gene name)|psi-mi:SPAG4(display_short)|uniprotkb:SUN4(gene name synonym)|uniprotkb:Outer dense fiber-associated protein SPAG4(gene name synonym)|uniprotkb:SUN domain-containing protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10820396|imex:IM-24270-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_003107.1|ensembl:ENSG00000061656(gene)|ensembl:ENST00000374273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR027776 - - - figure legend:Fig. 4B, Fig.S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2015/05/12 2015/05/15 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:mc3+VLMGxLPQFQFJiVsoR+oizfk9606 rigid:8hn4g/ai79kN8ochN3fW9+oeg4w false green fluorescent protein tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:P20700 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10820442|imex:IM-24270-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N - - - figure legend:"Fig4B, Fig 6A, Fig. S5, Fig.7 (first panel)"|comment:"SEPT12 (D197N) and SEPT12Del (c474G>A) reduced the ability of SEPT12 to interact with SPAG4. SEPT12 (T89M) and SEPT12Del (c474G>A) did not detect LAMINB1 as interactor"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2015/05/12 2015/05/19 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 rigid:c1tUt6OKWHAfiUj9toupZxxa09Y false green fluorescent protein tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q9NPE6 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-10819434|uniprotkb:O43648|ensembl:ENSP00000363391 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:spag4_human(display_long)|uniprotkb:SPAG4(gene name)|psi-mi:SPAG4(display_short)|uniprotkb:SUN4(gene name synonym)|uniprotkb:Outer dense fiber-associated protein SPAG4(gene name synonym)|uniprotkb:SUN domain-containing protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10820442|imex:IM-24270-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_003107.1|ensembl:ENSG00000061656(gene)|ensembl:ENST00000374273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR027776 - - - figure legend:"Fig4B, Fig 6A, Fig. S5, Fig.7 (first panel)"|comment:"SEPT12 (D197N) and SEPT12Del (c474G>A) reduced the ability of SEPT12 to interact with SPAG4. SEPT12 (T89M) and SEPT12Del (c474G>A) did not detect LAMINB1 as interactor"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2015/05/12 2015/05/19 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:mc3+VLMGxLPQFQFJiVsoR+oizfk9606 rigid:c1tUt6OKWHAfiUj9toupZxxa09Y false green fluorescent protein tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NPE6 uniprotkb:Q8IYM1 intact:EBI-10819434|uniprotkb:O43648|ensembl:ENSP00000363391 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:spag4_human(display_long)|uniprotkb:SPAG4(gene name)|psi-mi:SPAG4(display_short)|uniprotkb:SUN4(gene name synonym)|uniprotkb:Outer dense fiber-associated protein SPAG4(gene name synonym)|uniprotkb:SUN domain-containing protein 4(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0428"(imaging technique) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10821149|imex:IM-24270-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003107.1|ensembl:ENSG00000061656(gene)|ensembl:ENST00000374273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR027776 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL go:"GO:0097225"(sperm midpiece) - - figure legend:Fig.3A Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2015/05/12 2015/05/28 rogid:mc3+VLMGxLPQFQFJiVsoR+oizfk9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:8hn4g/ai79kN8ochN3fW9+oeg4w false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P20700 uniprotkb:Q8IYM1 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0428"(imaging technique) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10825019|imex:IM-24270-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL go:"GO:0097225"(sperm midpiece) - - figure legend:Fig 6Bd|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2015/05/12 2015/05/28 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:yA+fSN4Z82uWZHpe/YItKH6Ao90 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9NPE6 uniprotkb:Q8IYM1 intact:EBI-10819434|uniprotkb:O43648|ensembl:ENSP00000363391 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:spag4_human(display_long)|uniprotkb:SPAG4(gene name)|psi-mi:SPAG4(display_short)|uniprotkb:SUN4(gene name synonym)|uniprotkb:Outer dense fiber-associated protein SPAG4(gene name synonym)|uniprotkb:SUN domain-containing protein 4(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10821176|imex:IM-24270-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003107.1|ensembl:ENSG00000061656(gene)|ensembl:ENST00000374273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR027776 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/05/12 2015/05/18 rogid:mc3+VLMGxLPQFQFJiVsoR+oizfk9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:8hn4g/ai79kN8ochN3fW9+oeg4w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NPE6 uniprotkb:Q8IYM1 intact:EBI-10819434|uniprotkb:O43648|ensembl:ENSP00000363391 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:spag4_human(display_long)|uniprotkb:SPAG4(gene name)|psi-mi:SPAG4(display_short)|uniprotkb:SUN4(gene name synonym)|uniprotkb:Outer dense fiber-associated protein SPAG4(gene name synonym)|uniprotkb:SUN domain-containing protein 4(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10824887|imex:IM-24270-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003107.1|ensembl:ENSG00000061656(gene)|ensembl:ENST00000374273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR027776 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:Fig 5A Fig 5B Fig 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2015/05/12 2015/05/28 rogid:mc3+VLMGxLPQFQFJiVsoR+oizfk9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:8hn4g/ai79kN8ochN3fW9+oeg4w false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IYM1 uniprotkb:P07942 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Yeh et al. (2014) pubmed:25775403|imex:IM-24270 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10824934|imex:IM-24270-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2 - - - figure legend:Fig. 6B a-b-c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2015/05/12 2015/05/28 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606 rigid:dxgdflCaA/xtpEdXS8nV5h86gao false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)