#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5TC82	intact:EBI-10816060	intact:EBI-7958436|uniprotkb:Q5W180|uniprotkb:Q8IVE6|intact:MINT-2809509|uniprotkb:Q8N9V1|uniprotkb:B3KVK1|uniprotkb:Q5W181|ensembl:ENSP00000258349|ensembl:ENSP00000356669	rnacentral:URS00005E1F00_9606	psi-mi:rc3h1_human(display_long)|uniprotkb:RC3H1(gene name)|psi-mi:RC3H1(display_short)|uniprotkb:KIAA2025(gene name synonym)|uniprotkb:RNF198(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:RING finger protein 198(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:mir146a-1(display_short)|psi-mi:EBI-10816060(display_long)	psi-mi:"MI:1017"(rna immunoprecipitation)	Srivastava et al. (2014)	pubmed:25697406|imex:IM-24172	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10815879|imex:IM-24172-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	refseq:NP_001287779.1|refseq:NP_001287780.1|refseq:NP_001287781.1|refseq:NP_742068.1|ensembl:ENSG00000135870(gene)|ensembl:ENST00000258349(transcript)|ensembl:ENST00000367696(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:3X1O|rcsb pdb:4QIK|rcsb pdb:4QIL|rcsb pdb:4ULW|rcsb pdb:4YWQ	-	-	comment:mint|function:Represses ICOS function, an essential co-stimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1	-	figure legend:Fig5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t-cell)|taxid:9606(Homo sapiens)	-	2015/05/06	2015/05/13	rogid:eUDs8kX7shkMGYCRqyWilnNF/+A9606	-	-	false	-	-	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
intact:EBI-10819394	uniprotkb:Q4VGL6	-	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:mmu-mir146a(display_short)|psi-mi:EBI-10819394(display_long)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Srivastava et al. (2014)	pubmed:25697406|imex:IM-24172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816119|imex:IM-24172-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	-	-	-	figure legend:Fig5EF|comment:Ronquin Mutation M199R maintains the binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:370.0x10^-9(molar)	2015/05/06	2015/05/13	-	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	-	false	biotin tag:n-n	sufficient binding region:1-484|glutathione s tranferase tag:?-?|mutation decreasing interaction strength:199-199	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8CJG0	uniprotkb:Q4VGL6	intact:EBI-528299|uniprotkb:A1A563|uniprotkb:Q4VAB3|uniprotkb:Q571J6|ensembl:ENSMUSP00000042207	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:ago2_mouse(display_long)|uniprotkb:Ago2(gene name)|psi-mi:Ago2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:Eif2c2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:Kiaa4215(gene name synonym)|uniprotkb:Piwi/argonaute family protein meIF2C2(gene name synonym)|uniprotkb:Protein slicer(gene name synonym)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Srivastava et al. (2014)	pubmed:25697406|imex:IM-24172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816359|imex:IM-24172-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_694818.3|ensembl:ENSMUSG00000036698(gene)|ensembl:ENSMUST00000044113(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016442"(RISC complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q8CJG0|reactome:R-MMU-203927|reactome:R-MMU-426486|reactome:R-MMU-426496|reactome:R-MMU-5578749|dip:DIP-35014N	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	-	-	-	figure legend:Fig7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/05/06	2015/05/13	rogid:1waGxV2TyNC9zsGyfTKHjUd1ENo10090	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rigid:Nui8UnlKHEaCFqigbiIX5lWVY6M	false	flag tag:c-c	v5 tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UKV8	uniprotkb:Q5TC82	intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592	intact:EBI-7958436|uniprotkb:Q5W180|uniprotkb:Q8IVE6|intact:MINT-2809509|uniprotkb:Q8N9V1|uniprotkb:B3KVK1|uniprotkb:Q5W181|ensembl:ENSP00000258349|ensembl:ENSP00000356669	psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym)	psi-mi:rc3h1_human(display_long)|uniprotkb:RC3H1(gene name)|psi-mi:RC3H1(display_short)|uniprotkb:KIAA2025(gene name synonym)|uniprotkb:RNF198(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:RING finger protein 198(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Srivastava et al. (2014)	pubmed:25697406|imex:IM-24172	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816495|imex:IM-24172-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N	refseq:NP_001287779.1|refseq:NP_001287780.1|refseq:NP_001287781.1|refseq:NP_742068.1|ensembl:ENSG00000135870(gene)|ensembl:ENST00000258349(transcript)|ensembl:ENST00000367696(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:3X1O|rcsb pdb:4QIK|rcsb pdb:4QIL|rcsb pdb:4ULW|rcsb pdb:4YWQ	-	-	comment:mint|function:Represses ICOS function, an essential co-stimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1	figure legend:Fig7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/05/06	2015/05/08	rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606	rogid:eUDs8kX7shkMGYCRqyWilnNF/+A9606	rigid:gP9Mb+vVif5Fas3DWNNTG5RpJ6M	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q5TC82	uniprotkb:P26196	intact:EBI-7958436|uniprotkb:Q5W180|uniprotkb:Q8IVE6|intact:MINT-2809509|uniprotkb:Q8N9V1|uniprotkb:B3KVK1|uniprotkb:Q5W181|ensembl:ENSP00000258349|ensembl:ENSP00000356669	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	psi-mi:rc3h1_human(display_long)|uniprotkb:RC3H1(gene name)|psi-mi:RC3H1(display_short)|uniprotkb:KIAA2025(gene name synonym)|uniprotkb:RNF198(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:RING finger protein 198(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Srivastava et al. (2014)	pubmed:25697406|imex:IM-24172	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816971|imex:IM-24172-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001287779.1|refseq:NP_001287780.1|refseq:NP_001287781.1|refseq:NP_742068.1|ensembl:ENSG00000135870(gene)|ensembl:ENST00000258349(transcript)|ensembl:ENST00000367696(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:3X1O|rcsb pdb:4QIK|rcsb pdb:4QIL|rcsb pdb:4ULW|rcsb pdb:4YWQ	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	-	comment:mint|function:Represses ICOS function, an essential co-stimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1	-	figure legend:Fig7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/05/06	2015/05/08	rogid:eUDs8kX7shkMGYCRqyWilnNF/+A9606	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rigid:0SJSbKcXQ7UzjmnymggDDYHWSuA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8CJG0	uniprotkb:Q4VGL6	intact:EBI-528299|uniprotkb:A1A563|uniprotkb:Q4VAB3|uniprotkb:Q571J6|ensembl:ENSMUSP00000042207	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:ago2_mouse(display_long)|uniprotkb:Ago2(gene name)|psi-mi:Ago2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:Eif2c2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:Kiaa4215(gene name synonym)|uniprotkb:Piwi/argonaute family protein meIF2C2(gene name synonym)|uniprotkb:Protein slicer(gene name synonym)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Srivastava et al. (2014)	pubmed:25697406|imex:IM-24172	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816642|imex:IM-24172-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_694818.3|ensembl:ENSMUSG00000036698(gene)|ensembl:ENSMUST00000044113(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016442"(RISC complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q8CJG0|reactome:R-MMU-203927|reactome:R-MMU-426486|reactome:R-MMU-426496|reactome:R-MMU-5578749|dip:DIP-35014N	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	-	-	-	figure legend:Suppl. Fig5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-el4)|taxid:10090(Mus musculus)	-	2015/05/06	2015/05/08	rogid:1waGxV2TyNC9zsGyfTKHjUd1ENo10090	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rigid:Nui8UnlKHEaCFqigbiIX5lWVY6M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)