#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Z2L0	uniprotkb:P00758	intact:EBI-920336|uniprotkb:A1L125|uniprotkb:Q3MHT8|uniprotkb:Q5M944|uniprotkb:Q5M972|uniprotkb:Q6IN28|uniprotkb:Q6P9W9|ensembl:ENSRNOP00000008477	intact:EBI-10758809|uniprotkb:Q68G17	psi-mi:vdac1_rat(display_long)|uniprotkb:Vdac1(gene name)|psi-mi:Vdac1(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)	psi-mi:klk1_rat(display_long)|uniprotkb:Gamma-NGF(gene name synonym)|uniprotkb:Nerve growth factor gamma chain(gene name synonym)|uniprotkb:PS kallikrein(gene name synonym)|uniprotkb:Pancreatic kallikrein(gene name synonym)|uniprotkb:RGK-1(gene name synonym)|uniprotkb:Tissue kallikrein(gene name synonym)|uniprotkb:True tissue kallikrein(gene name synonym)|uniprotkb:Ngfg(gene name)|psi-mi:Ngfg(display_short)|uniprotkb:Klk-1(gene name synonym)|uniprotkb:Klk1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Youcef et al. (2015)	pubmed:25623731|imex:IM-24034	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10758756|imex:IM-24034-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621575|refseq:NP_112643.1|ensembl:ENSRNOG00000006375(gene)|ensembl:ENSRNOT00000008477(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:Q9Z2L0|reactome:R-RNO-5205685|reactome:R-RNO-5689880|reactome:R-RNO-70268|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005253"(anion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|dip:DIP-37068N	rgd:3175|reactome:R-RNO-1592389|reactome:R-RNO-381426|interpro:IPR033116|refseq:NP_113711.1|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR018114|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0031638"(zymogen activation)|interpro:IPR043504	-	-	-	figure legend:3B-1|dataset:Cardiac - Interactions involving cardiac related proteins|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-h9c2)|taxid:10116(h9c2 rat myoblasts)	-	2015/03/24	2015/03/27	rogid:9tTXatzG8BVX217+t0HLppj0oAY10116	rogid:NDUWNN6b1AA1yhV+9arhlTpDPAg10116	rigid:JM3jxl1b68obIbSXB9Eopqjp+mk	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q75Q41	uniprotkb:P00758	intact:EBI-1180634|ensembl:ENSRNOP00000019323	intact:EBI-10758809|uniprotkb:Q68G17	psi-mi:tom22_rat(display_long)|uniprotkb:Tomm22(gene name)|psi-mi:Tomm22(display_short)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:Tom22(gene name synonym)	psi-mi:klk1_rat(display_long)|uniprotkb:Gamma-NGF(gene name synonym)|uniprotkb:Nerve growth factor gamma chain(gene name synonym)|uniprotkb:PS kallikrein(gene name synonym)|uniprotkb:Pancreatic kallikrein(gene name synonym)|uniprotkb:RGK-1(gene name synonym)|uniprotkb:Tissue kallikrein(gene name synonym)|uniprotkb:True tissue kallikrein(gene name synonym)|uniprotkb:Ngfg(gene name)|psi-mi:Ngfg(display_short)|uniprotkb:Klk-1(gene name synonym)|uniprotkb:Klk1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Youcef et al. (2015)	pubmed:25623731|imex:IM-24034	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10758794|imex:IM-24034-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1303260|refseq:NP_997679.1|ensembl:ENSRNOG00000014058(gene)|ensembl:ENSRNOT00000019323(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|reactome:R-RNO-5205685	rgd:3175|reactome:R-RNO-1592389|reactome:R-RNO-381426|interpro:IPR033116|refseq:NP_113711.1|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR018114|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0031638"(zymogen activation)|interpro:IPR043504	-	-	-	figure legend:3B-2|dataset:Cardiac - Interactions involving cardiac related proteins|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-h9c2)|taxid:10116(h9c2 rat myoblasts)	-	2015/03/24	2015/03/27	rogid:1LjO56QiBr+SqSv0IPBTh5MT0T810116	rogid:NDUWNN6b1AA1yhV+9arhlTpDPAg10116	rigid:8tNZbgYrdSOhsThIUOSAHt19ZoE	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P29117	uniprotkb:P00758	intact:EBI-6454979|ensembl:ENSRNOP00000014382	intact:EBI-10758809|uniprotkb:Q68G17	psi-mi:ppif_rat(display_long)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Ppif(gene name)|psi-mi:Ppif(display_short)|uniprotkb:Cyclophilin F(gene name synonym)|uniprotkb:Rotamase F(gene name synonym)	psi-mi:klk1_rat(display_long)|uniprotkb:Gamma-NGF(gene name synonym)|uniprotkb:Nerve growth factor gamma chain(gene name synonym)|uniprotkb:PS kallikrein(gene name synonym)|uniprotkb:Pancreatic kallikrein(gene name synonym)|uniprotkb:RGK-1(gene name synonym)|uniprotkb:Tissue kallikrein(gene name synonym)|uniprotkb:True tissue kallikrein(gene name synonym)|uniprotkb:Ngfg(gene name)|psi-mi:Ngfg(display_short)|uniprotkb:Klk-1(gene name synonym)|uniprotkb:Klk1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Youcef et al. (2015)	pubmed:25623731|imex:IM-24034	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10758800|imex:IM-24034-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000010558(gene)|ensembl:ENSRNOT00000014382(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0002931"(response to ischemia)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0005737"(cytoplasm)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|rcsb pdb:4TOT|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010849"(regulation of proton-transporting ATPase activity, rotational mechanism)|go:"GO:0010939"(regulation of necrotic cell death)|go:"GO:0016018"(cyclosporin A binding)|refseq:NP_758443.1|rgd:628670	rgd:3175|reactome:R-RNO-1592389|reactome:R-RNO-381426|interpro:IPR033116|refseq:NP_113711.1|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR018114|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0031638"(zymogen activation)|interpro:IPR043504	-	-	-	figure legend:3B-3|dataset:Cardiac - Interactions involving cardiac related proteins|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-h9c2)|taxid:10116(h9c2 rat myoblasts)	-	2015/03/24	2015/03/27	rogid:erVXqkKJG1Su/VgHy/O5qzC2aVs10116	rogid:NDUWNN6b1AA1yhV+9arhlTpDPAg10116	rigid:A+gg1GGWViKkVCdUrdm4Lfw1GJc	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P29117	uniprotkb:P08934-PRO_0000006697	intact:EBI-6454979|ensembl:ENSRNOP00000014382	intact:EBI-10758786	psi-mi:ppif_rat(display_long)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Ppif(gene name)|psi-mi:Ppif(display_short)|uniprotkb:Cyclophilin F(gene name synonym)|uniprotkb:Rotamase F(gene name synonym)	psi-mi:p08934-pro_0000006697(display_long)|uniprotkb:Kng1(gene name)|psi-mi:Kng1(display_short)|uniprotkb:Kng(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Youcef et al. (2015)	pubmed:25623731|imex:IM-24034	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10758805|imex:IM-24034-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000010558(gene)|ensembl:ENSRNOT00000014382(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0002931"(response to ischemia)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0005737"(cytoplasm)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|rcsb pdb:4TOT|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010849"(regulation of proton-transporting ATPase activity, rotational mechanism)|go:"GO:0010939"(regulation of necrotic cell death)|go:"GO:0016018"(cyclosporin A binding)|refseq:NP_758443.1|rgd:628670	intact:EBI-10758758(chain-parent)	go:"GO:0005737"(cytoplasm)	-	chain-seq-start:381|chain-seq-end:389	figure legend:3B-4|dataset:Cardiac - Interactions involving cardiac related proteins|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-h9c2)|taxid:10116(h9c2 rat myoblasts)	-	2015/03/24	2015/03/27	rogid:erVXqkKJG1Su/VgHy/O5qzC2aVs10116	rogid:6gWGwqbaJ8YYHgtSA8iAETGldvg10116	rigid:PtEIT+LjCiHKQIr231eC6Z7Njqo	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)