#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9HD23 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-6164303|ensembl:ENSP00000367637|uniprotkb:B4DQL2|uniprotkb:A8K4U3|uniprotkb:B3KNN2|uniprotkb:Q5T3Y1|uniprotkb:Q6NTG4|uniprotkb:Q96KF8|uniprotkb:Q9BVP1 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:mrs2_human(display_long)|uniprotkb:MRS2(gene name)|psi-mi:MRS2(display_short)|uniprotkb:HPT(gene name synonym)|uniprotkb:MRS2-like protein(gene name synonym)|uniprotkb:MRS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000124532(gene)|ensembl:ENST00000378386(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045016"(mitochondrial magnesium ion transmembrane transport)|go:"GO:0055085"(transmembrane transport)|interpro:IPR039204|reactome:R-HSA-5223345|refseq:NP_001273193.1|refseq:NP_001273194.1|refseq:NP_001273195.1|refseq:NP_065713.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:qvKwgSW3lcwro4mQsW0ex2yN6IM9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q96AG4 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9BRP8 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q8NG48 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-11599058|uniprotkb:Q96FW2|uniprotkb:Q9NVQ3|ensembl:ENSP00000318423 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:lines_human(display_long)|uniprotkb:Wnt-signaling molecule Lines homolog 1(gene name synonym)|uniprotkb:LINS1(gene name)|psi-mi:LINS1(display_short)|uniprotkb:LINS(gene name synonym)|uniprotkb:WINS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001035706.1|refseq:XP_005254998.1|ensembl:ENSG00000140471(gene)|ensembl:ENST00000314742(transcript)|go:"GO:0050890"(cognition)|interpro:IPR024875|interpro:IPR029415|interpro:IPR032794 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:QN4z7z+27goQ9TBCkefo3Gl2ZxE9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q96DV4 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-720441|uniprotkb:Q96Q66|uniprotkb:Q9P0B9|uniprotkb:B3KN96|ensembl:ENSP00000308275 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:rm38_human(display_long)|uniprotkb:MRPL38(gene name)|psi-mi:MRPL38(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL38(gene name synonym)|uniprotkb:HSPC262(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_115867.2|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:6ZSC|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000204316(gene)|ensembl:ENST00000309352(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:Q96DV4|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:U9R8ZJYdURLjkBNd5LZOt4wsWD89606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9P015 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2371967|uniprotkb:Q96Q54|uniprotkb:Q9H0Y1|ensembl:ENSP00000260102 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:rm15_human(display_long)|uniprotkb:MRPL15(gene name)|psi-mi:MRPL15(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL15m(gene name synonym)|uniprotkb:HSPC145(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_054894.1|ensembl:ENSG00000137547(gene)|ensembl:ENST00000260102(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR005749(Ribosomal protein L15, bacterial-type)|interpro:IPR021131|interpro:IPR030878|interpro:IPR036227|mint:Q9P015|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSA - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:efJei4RFNcTx2MqyMwdu7EXO1c09606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q13405 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-5325200|ensembl:ENSP00000279242|ensembl:ENSP00000434190|uniprotkb:B2R4G6 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:rm49_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL49(gene name synonym)|uniprotkb:MRPL49(gene name)|psi-mi:MRPL49(display_short)|uniprotkb:C11orf4(gene name synonym)|uniprotkb:NOF1(gene name synonym)|uniprotkb:Neighbor of FAU(gene name synonym)|uniprotkb:Protein NOF1(gene name synonym)|uniprotkb:OK/SW-cl.67(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) interpro:IPR007740(Ribosomal protein L49/IMG2)|mint:Q13405|rcsb pdb:3J7Y|ensembl:ENSG00000149792(gene)|ensembl:ENST00000279242(transcript)|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|ensembl:ENST00000526319(transcript)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6I9R|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|go:"GO:0005762"(mitochondrial large ribosomal subunit)|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|go:"GO:0006412"(translation)|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|rcsb pdb:7OF6|reactome:R-HSA-5419276|refseq:NP_004918.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:rSs3oQ/ABEywPjx7fwVEuT6fsdQ9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q15672 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-1797287|uniprotkb:Q92487|uniprotkb:Q99804|uniprotkb:A4D128|ensembl:ENSP00000242261 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:twst1_human(display_long)|uniprotkb:H-twist(gene name synonym)|uniprotkb:TWIST1(gene name)|psi-mi:TWIST1(display_short)|uniprotkb:TWIST(gene name synonym)|uniprotkb:BHLHA38(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_000465.1|refseq:XP_011513798.1|dip:DIP-45974N|ensembl:ENSG00000122691(gene)|ensembl:ENST00000242261(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032502"(developmental process)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070888"(E-box binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000780"(negative regulation of double-strand break repair)|go:"GO:2000793"(cell proliferation involved in heart valve development)|go:"GO:2000802"(positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|rcsb pdb:2MJV|reactome:R-HSA-6785807|reactome:R-HSA-8878166|reactome:R-HSA-8939902 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:1+WEEh0ruAAKCxlJQCVzBqTrhIM9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q15020 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-308619|uniprotkb:Q2M2H0|uniprotkb:Q58F06|uniprotkb:Q8IUS1|uniprotkb:Q96J95|uniprotkb:A8K2E4|uniprotkb:B7ZKM0|ensembl:ENSP00000449386|intact:EBI-11138149 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:sart3_human(display_long)|uniprotkb:KIAA0156(gene name synonym)|uniprotkb:SART3(gene name)|psi-mi:SART3(display_short)|uniprotkb:TIP110(gene name synonym)|uniprotkb:Tat-interacting protein of 110 kDa(gene name synonym)|uniprotkb:p110 nuclear RNA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000075856(gene)|ensembl:ENST00000546815(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|mint:Q15020|rcsb pdb:2DO4|rcsb pdb:5CTQ|rcsb pdb:5CTR|rcsb pdb:5CTT|rcsb pdb:5JJW|rcsb pdb:5JJX|rcsb pdb:5JPZ|refseq:NP_055521.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:/71mWOMJti/LCvNo2WjCAmIYUCk9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9NWU5 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-5461867|uniprotkb:Q5H9Q1|uniprotkb:Q96Q51|uniprotkb:Q9P006|intact:EBI-6137918|uniprotkb:A6NGJ8|ensembl:ENSP00000431040 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:rm22_human(display_long)|uniprotkb:MRPL22(gene name)|psi-mi:MRPL22(display_short)|uniprotkb:MRPL25(gene name synonym)|uniprotkb:RPML25(gene name synonym)|uniprotkb:39S ribosomal protein L25, mitochondrial(gene name synonym)|uniprotkb:HSPC158(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL22m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001014990.1|refseq:NP_054899.2|ensembl:ENSG00000082515(gene)|ensembl:ENST00000523037(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|interpro:IPR036394|mint:Q9NWU5|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:Nmwjb2QTu0IyJMS0SufI3PsBwmM9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:P67870 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9Y3D3 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-1049319|uniprotkb:Q96Q60|ensembl:ENSP00000362036|uniprotkb:B4E032 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:rt16_human(display_long)|uniprotkb:MRPS16(gene name)|psi-mi:MRPS16(display_short)|uniprotkb:RPMS16(gene name synonym)|uniprotkb:CGI-132(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS16m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_057149.1|ensembl:ENSG00000182180(gene)|ensembl:ENST00000372945(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|mint:Q9Y3D3|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|rcsb pdb:7A5F|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5G - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:jejigKZMzvzmWuhMXnBB3lNsShU9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q96DH6 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2462339|uniprotkb:Q7Z6M7|uniprotkb:Q8N9T4|ensembl:ENSP00000284073|ensembl:ENSP00000502137 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:msi2h_human(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_620412.1|refseq:NP_733839.1|ensembl:ENSG00000153944(gene)|ensembl:ENST00000284073(transcript)|ensembl:ENST00000674964(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048864"(stem cell development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|mint:Q96DH6|rcsb pdb:6C8U|rcsb pdb:6DBP|rcsb pdb:6NTY|reactome:R-HSA-9013418 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:/tSHeNbYwUTw4kGlF3LQw+5OVjs9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9BZ29 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q13099 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-347427|uniprotkb:A2A491|uniprotkb:Q5SZJ6|uniprotkb:Q8N719|uniprotkb:B4DUS2|ensembl:ENSP00000261632 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:ift88_human(display_long)|uniprotkb:IFT88(gene name)|psi-mi:IFT88(display_short)|uniprotkb:TG737(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 10(gene name synonym)|uniprotkb:Recessive polycystic kidney disease protein Tg737 homolog(gene name synonym)|uniprotkb:TTC10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_783195.2|refseq:XP_011533543.1|refseq:XP_016876247.1|refseq:NP_001305420.1|interpro:IPR019734|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-5610787|reactome:R-HSA-5620924|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0019894"(kinesin binding)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR006597(Sel1-like)|ensembl:ENSG00000032742(gene)|ensembl:ENST00000351808(transcript)|go:"GO:0001822"(kidney development)|refseq:XP_005266610.1|refseq:NP_006522.2|refseq:XP_006719933.1|refseq:XP_011533544.1|refseq:XP_011533545.1|refseq:XP_016876246.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:kUeWmfrvdFuel6K1rJDf+5AtNAA9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9Y3D5 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-5453854|ensembl:ENSP00000295491 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:rt18c_human(display_long)|uniprotkb:MRPS18C(gene name)|psi-mi:MRPS18C(display_short)|uniprotkb:28S ribosomal protein S18-1, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18c(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18m(gene name synonym)|uniprotkb:CGI-134(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001284698.1|refseq:NP_001284699.1|refseq:NP_057151.1|ensembl:ENSG00000163319(gene)|ensembl:ENST00000295491(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001648(Ribosomal protein S18)|interpro:IPR018275|interpro:IPR036870|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:WFVJqLIjMUdsPmYVjn7uvIxy+c49606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:P55209 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q2KHT3 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2873257|ensembl:ENSP00000387122|uniprotkb:Q6ZTB2|uniprotkb:O15058 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:cl16a_human(display_long)|uniprotkb:CLEC16A(gene name)|psi-mi:CLEC16A(display_short)|uniprotkb:KIAA0350(gene name synonym)|uniprotkb:C-type lectin domain family 16 member A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000038532(gene)|ensembl:ENST00000409790(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031982"(vesicle)|go:"GO:0036020"(endolysosome membrane)|go:"GO:1901096"(regulation of autophagosome maturation)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904766"(negative regulation of macroautophagy by TORC1 signaling)|interpro:IPR019155|interpro:IPR039272|refseq:NP_001230332.1|refseq:NP_056041.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:dR07OPCgk8rvhcNRGgUM09OjvzY9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:P68400 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9C0C9 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q2TBE0 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-5453285|intact:EBI-10174974|uniprotkb:A8KAD6|uniprotkb:A4FU66|uniprotkb:A4FU67|uniprotkb:A4FU68|uniprotkb:Q6PHW1|uniprotkb:Q96MI1|ensembl:ENSP00000282251 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:c19l2_human(display_long)|uniprotkb:CWF19L2(gene name)|psi-mi:CWF19L2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_689647.2|ensembl:ENSG00000152404(gene)|ensembl:ENST00000282251(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR006767(Protein similar to CwfJ, C-terminal 2)|interpro:IPR006768(Protein similar to CwfJ, C-terminal 1)|interpro:IPR036265|interpro:IPR040194|rcsb pdb:6ID0|rcsb pdb:6ID1 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:su0efFG2+hfeYLYnCe/Ztij078U9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9Y6H1 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q13724 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|ensembl:ENSP00000410992|uniprotkb:F5H6D0 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001139630.1|refseq:NP_006293.2|ensembl:ENSG00000115275(gene)|ensembl:ENST00000448666(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0015926"(glucosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q99733 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422269|imex:IM-26093-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733 - chain-seq-start:2|chain-seq-end:191 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2020/08/14 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606 rigid:NLqg4M+ztpW0C6RU1zOpxj2lpmc false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:P46379 intact:EBI-6901441 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q8N163 intact:EBI-6901441 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q9UKV3 intact:EBI-6901441 intact:EBI-396258|uniprotkb:O75158|uniprotkb:Q9UG91|uniprotkb:Q9UKV1|uniprotkb:Q9UKV2|uniprotkb:D3DS45|uniprotkb:B2RTT4|ensembl:ENSP00000262710 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:acinu_human(display_long)|uniprotkb:ACIN1(gene name)|psi-mi:ACIN1(display_short)|uniprotkb:ACINUS(gene name synonym)|uniprotkb:KIAA0670(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001158286.1|refseq:NP_001158287.1|refseq:NP_001158288.1|refseq:NP_001158289.1|refseq:NP_055792.1|refseq:XP_005267475.1|ensembl:ENSG00000100813(gene)|ensembl:ENST00000262710(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034257|interpro:IPR035979|interpro:IPR036361|mint:Q9UKV3|rcsb pdb:6G6S|reactome:R-HSA-111465|interpro:IPR032552|dip:DIP-32963N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:dzHCIefdTYTGEk+qXNwlK2Phybw9606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q96I24 intact:EBI-6901441 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q92879 intact:EBI-6901441 intact:EBI-713032|ensembl:ENSP00000351409|uniprotkb:Q4LE52|uniprotkb:Q9NP83|uniprotkb:Q9NR06|uniprotkb:D3DQS0|uniprotkb:B4E2U5|uniprotkb:F8W940 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:celf1_human(display_long)|uniprotkb:Bruno-like protein 2(gene name synonym)|uniprotkb:RNA-binding protein BRUNOL-2(gene name synonym)|uniprotkb:CUG triplet repeat RNA-binding protein 1(gene name synonym)|uniprotkb:Deadenylation factor CUG-BP(gene name synonym)|uniprotkb:50 kDa nuclear polyadenylated RNA-binding protein(gene name synonym)|uniprotkb:Embryo deadenylation element-binding protein homolog(gene name synonym)|uniprotkb:CELF1(gene name)|psi-mi:CELF1(display_short)|uniprotkb:BRUNOL2(gene name synonym)|uniprotkb:CUGBP(gene name synonym)|uniprotkb:NAB50(gene name synonym)|uniprotkb:CUGBP1(gene name synonym)|uniprotkb:CUG-BP- and ETR-3-like factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000149187(gene)|ensembl:ENST00000358597(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0007281"(germ cell development)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034196|interpro:IPR034198|interpro:IPR034199|interpro:IPR035979|mint:Q92879|rcsb pdb:2CPZ|rcsb pdb:2DHS|rcsb pdb:2RQ4|rcsb pdb:2RQC|rcsb pdb:3NMR|rcsb pdb:3NNA|rcsb pdb:3NNC|go:"GO:0016020"(membrane)|rcsb pdb:3NNH|go:"GO:0016246"(RNA interference)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042835"(BRE binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061157"(mRNA destabilization)|refseq:XP_011518161.1|refseq:NP_001020767.1|refseq:NP_001166110.1|refseq:NP_001166111.1|refseq:NP_006551.1|refseq:NP_941989.1|ensembl:ENST00000310513|ensembl:ENSP00000308386|ensembl:ENSP00000351409|ensembl:ENST00000361904|ensembl:ENSP00000354639|ensembl:ENST00000395290|ensembl:ENSP00000378705|ensembl:ENST00000395292|ensembl:ENSP00000378706|ensembl:ENST00000532048|ensembl:ENSP00000435926|refseq:XP_016872613.1|refseq:XP_016872614.1|refseq:XP_016872615.1|refseq:XP_016872616.1|refseq:XP_016872617.1|refseq:XP_016872618.1|refseq:XP_016872619.1|refseq:XP_016872620.1|refseq:XP_016872621.1|refseq:XP_016872622.1|refseq:XP_016872623.1|refseq:XP_016872624.1 - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:MUTvmDd0BGmmliUR0FEiHnZq0v49606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q99856 intact:EBI-6901441 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q9UDY4 intact:EBI-6901441 intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599079|imex:IM-26093-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_008965.2|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|ensembl:ENSG00000162616(gene)|ensembl:ENST00000370763(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UDY4 - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606 rigid:eMxlI92IDhtVJ5N7u/NoXvB/tY8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:O00422 intact:EBI-6901441 intact:EBI-1044156|uniprotkb:Q2TTR4|uniprotkb:Q6IAW9|uniprotkb:Q8N606|uniprotkb:Q9UF14|ensembl:ENSP00000475925|uniprotkb:B2R494|uniprotkb:X6RAL5 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:sap18_human(display_long)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 38 protein(gene name synonym)|uniprotkb:2HOR0202(gene name synonym)|uniprotkb:SAP18(gene name)|psi-mi:SAP18(display_short)|uniprotkb:GIG38(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000150459(gene)|ensembl:ENST00000607003(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O00422|rcsb pdb:2HDE|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|refseq:NP_005861.2|dip:DIP-33590N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:eJoksFCc7vBoAjJEpnXJvc/yg+Q9606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:P29508 intact:EBI-6901441 intact:EBI-359110|uniprotkb:Q53H28|uniprotkb:Q86VF3|uniprotkb:Q86W04|uniprotkb:Q8IWL4|uniprotkb:Q8IXI3|uniprotkb:Q9BYF8|uniprotkb:Q53YB5|uniprotkb:Q96J21|uniprotkb:B2RBT5|uniprotkb:A6NDM2|uniprotkb:B3W5Y6|ensembl:ENSP00000283752 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:spb3_human(display_long)|uniprotkb:SERPINB3(gene name)|psi-mi:SERPINB3(display_short)|uniprotkb:SCCA(gene name synonym)|uniprotkb:SCCA1(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen 1(gene name synonym)|uniprotkb:Protein T4-A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_008850.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P29508|rcsb pdb:2ZV6|rcsb pdb:4ZK0|rcsb pdb:4ZK3|reactome:R-HSA-6798695|ensembl:ENSG00000057149(gene)|ensembl:ENST00000283752(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity) - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:Q6rcSr7BU3XXRUX39SbdLT6Nm5s9606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:P46379 intact:EBI-6901441 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q8N163 intact:EBI-6901441 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q9UKV3 intact:EBI-6901441 intact:EBI-396258|uniprotkb:O75158|uniprotkb:Q9UG91|uniprotkb:Q9UKV1|uniprotkb:Q9UKV2|uniprotkb:D3DS45|uniprotkb:B2RTT4|ensembl:ENSP00000262710 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:acinu_human(display_long)|uniprotkb:ACIN1(gene name)|psi-mi:ACIN1(display_short)|uniprotkb:ACINUS(gene name synonym)|uniprotkb:KIAA0670(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001158286.1|refseq:NP_001158287.1|refseq:NP_001158288.1|refseq:NP_001158289.1|refseq:NP_055792.1|refseq:XP_005267475.1|ensembl:ENSG00000100813(gene)|ensembl:ENST00000262710(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034257|interpro:IPR035979|interpro:IPR036361|mint:Q9UKV3|rcsb pdb:6G6S|reactome:R-HSA-111465|interpro:IPR032552|dip:DIP-32963N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:dzHCIefdTYTGEk+qXNwlK2Phybw9606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:Q96I24 intact:EBI-6901441 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045595 uniprotkb:P48594 intact:EBI-6901441 intact:EBI-1055490|uniprotkb:A8K847|ensembl:ENSP00000343445 psi-mi:q99ib8-pro_0000045595(display_long) psi-mi:spb4_human(display_long)|uniprotkb:Squamous cell carcinoma antigen 2(gene name synonym)|uniprotkb:Leupin(gene name synonym)|uniprotkb:SERPINB4(gene name)|psi-mi:SERPINB4(display_short)|uniprotkb:SCCA2(gene name synonym)|uniprotkb:PI11(gene name synonym)|uniprotkb:Peptidase inhibitor 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599091|imex:IM-26093-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_778206.1|refseq:NP_002965.1|refseq:XP_011524440.1|ensembl:ENSG00000206073(gene)|ensembl:ENST00000341074(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042185|mint:P48594|interpro:IPR042178 - chain-seq-start:192|chain-seq-end:383 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:2jztNkYW0DUTz6ygVMOZp/7Xn8E356411 rogid:1kO3L409kom3vIvMuAuBuGZhiH89606 rigid:qJYNEinxzOjA8iFuQvqwcW0c6qo false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:O14828 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599103|imex:IM-26093-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606 rigid:+2c2ZnlaOvpcfpeh+f8bycBni5Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P21796 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599103|imex:IM-26093-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rigid:+2c2ZnlaOvpcfpeh+f8bycBni5Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:Q9BTV4 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599103|imex:IM-26093-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625) - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606 rigid:+2c2ZnlaOvpcfpeh+f8bycBni5Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:O14828 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599111|imex:IM-26093-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606 rigid:MDTmISbm/IoT3ZF1uVH3DyPaKto false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P21796 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599111|imex:IM-26093-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rigid:MDTmISbm/IoT3ZF1uVH3DyPaKto false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:O95758 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-1054362|uniprotkb:B1ALY6|uniprotkb:B3KME7|uniprotkb:B1ALY2|uniprotkb:B1ALY5|intact:EBI-2826029|uniprotkb:B1ALY3|uniprotkb:Q68DB9|uniprotkb:Q86YB3|uniprotkb:Q86YH9|intact:EBI-2952652|ensembl:ENSP00000363373 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:ptbp3_human(display_long)|uniprotkb:PTBP3(gene name)|psi-mi:PTBP3(display_short)|uniprotkb:ROD1(gene name synonym)|uniprotkb:Regulator of differentiation 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599118|imex:IM-26093-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001157262.1|refseq:NP_005147.3|refseq:NP_001231826.1|refseq:NP_001231827.1|refseq:NP_001157260.1|refseq:NP_001231825.1|refseq:XP_006717409.1|go:"GO:0008380"(RNA splicing)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR033110|interpro:IPR034326|interpro:IPR034798|interpro:IPR035979|ensembl:ENSG00000119314(gene)|ensembl:ENST00000374255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing) - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:fjlmh2VPnRuFkqK0M8xVbMmVaek9606 rigid:3Es2ZMa6AVyz4dxIdDXXmckNea4 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:P40227 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599118|imex:IM-26093-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:3Es2ZMa6AVyz4dxIdDXXmckNea4 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:P46379 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599118|imex:IM-26093-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rigid:3Es2ZMa6AVyz4dxIdDXXmckNea4 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:Q04837 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599118|imex:IM-26093-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:3Es2ZMa6AVyz4dxIdDXXmckNea4 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:Q7L5D6 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-711823|uniprotkb:A4D2Q1|uniprotkb:B3KNC7|uniprotkb:Q9UFC9|uniprotkb:Q9Y309|ensembl:ENSP00000265857 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:get4_human(display_long)|uniprotkb:CEE(gene name synonym)|uniprotkb:Conserved edge-expressed protein(gene name synonym)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:CGI-20(orf name)|uniprotkb:C7orf20(gene name synonym)|uniprotkb:TRC35(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 35 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599118|imex:IM-26093-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239857(gene)|ensembl:ENST00000265857(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0051087"(chaperone binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q7L5D6|rcsb pdb:6AU8|reactome:R-HSA-9609523|refseq:NP_057033.2 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:WbZJTGrC2/fB4iOFLJYn9MIWZFA9606 rigid:3Es2ZMa6AVyz4dxIdDXXmckNea4 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:Q05519 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-1051785|uniprotkb:Q5T758|uniprotkb:Q8IWE6|ensembl:ENSP00000359988 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:srs11_human(display_long)|uniprotkb:Arginine-rich 54 kDa nuclear protein(gene name synonym)|uniprotkb:SRSF11(gene name)|psi-mi:SRSF11(display_short)|uniprotkb:SFRS11(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599118|imex:IM-26093-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004759.1|refseq:NP_001177916.1|refseq:XP_011540729.1|ensembl:ENSG00000116754(gene)|ensembl:ENST00000370950(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034447|interpro:IPR035979|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:XP_016858301.1|refseq:XP_016858302.1 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/17 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:F6QVk0M0PqxLXIA1dgWyoFbwFHE9606 rigid:3Es2ZMa6AVyz4dxIdDXXmckNea4 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:O95758 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-1054362|uniprotkb:B1ALY6|uniprotkb:B3KME7|uniprotkb:B1ALY2|uniprotkb:B1ALY5|intact:EBI-2826029|uniprotkb:B1ALY3|uniprotkb:Q68DB9|uniprotkb:Q86YB3|uniprotkb:Q86YH9|intact:EBI-2952652|ensembl:ENSP00000363373 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:ptbp3_human(display_long)|uniprotkb:PTBP3(gene name)|psi-mi:PTBP3(display_short)|uniprotkb:ROD1(gene name synonym)|uniprotkb:Regulator of differentiation 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599129|imex:IM-26093-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001157262.1|refseq:NP_005147.3|refseq:NP_001231826.1|refseq:NP_001231827.1|refseq:NP_001157260.1|refseq:NP_001231825.1|refseq:XP_006717409.1|go:"GO:0008380"(RNA splicing)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR033110|interpro:IPR034326|interpro:IPR034798|interpro:IPR035979|ensembl:ENSG00000119314(gene)|ensembl:ENST00000374255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing) - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:fjlmh2VPnRuFkqK0M8xVbMmVaek9606 rigid:zaVM0iOjTJpjg3RDU4tH6b1DC40 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:P40227 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599129|imex:IM-26093-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:zaVM0iOjTJpjg3RDU4tH6b1DC40 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:P46379 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599129|imex:IM-26093-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rigid:zaVM0iOjTJpjg3RDU4tH6b1DC40 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:Q04837 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599129|imex:IM-26093-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:zaVM0iOjTJpjg3RDU4tH6b1DC40 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045596 uniprotkb:Q7L5D6 intact:EBI-6901449|intact:EBI-6927909 intact:EBI-711823|uniprotkb:A4D2Q1|uniprotkb:B3KNC7|uniprotkb:Q9UFC9|uniprotkb:Q9Y309|ensembl:ENSP00000265857 psi-mi:q99ib8-pro_0000045596(display_long) psi-mi:get4_human(display_long)|uniprotkb:CEE(gene name synonym)|uniprotkb:Conserved edge-expressed protein(gene name synonym)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:CGI-20(orf name)|uniprotkb:C7orf20(gene name synonym)|uniprotkb:TRC35(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 35 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599129|imex:IM-26093-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239857(gene)|ensembl:ENST00000265857(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0051087"(chaperone binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q7L5D6|rcsb pdb:6AU8|reactome:R-HSA-9609523|refseq:NP_057033.2 - chain-seq-start:384|chain-seq-end:750 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411 rogid:WbZJTGrC2/fB4iOFLJYn9MIWZFA9606 rigid:zaVM0iOjTJpjg3RDU4tH6b1DC40 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:C9JLW8 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-11599148|uniprotkb:Q6ZUL0|ensembl:ENSP00000409009|ensembl:ENSP00000445543|ensembl:ENSP00000458707|ensembl:ENSP00000458720|ensembl:ENSP00000499966|ensembl:ENSP00000500382|ensembl:ENSP00000500493|ensembl:ENSP00000500656 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:mcri1_human(display_long)|uniprotkb:MCRIP1(gene name)|psi-mi:MCRIP1(display_short)|uniprotkb:FAM195B(gene name synonym)|uniprotkb:GRAN2(gene name synonym)|uniprotkb:Granulin-2(gene name synonym)|uniprotkb:Protein FAM195B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599139|imex:IM-26093-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001087236.1|refseq:NP_997251.2|ensembl:ENST00000673154(transcript)|ensembl:ENST00000673369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|interpro:IPR029428|mint:C9JLW8|ensembl:ENSG00000225663(gene)|ensembl:ENSG00000288213(gene)|ensembl:ENST00000455127(transcript)|ensembl:ENST00000538396(transcript)|ensembl:ENST00000574190(transcript)|ensembl:ENST00000576730(transcript)|ensembl:ENST00000672201(transcript)|ensembl:ENST00000672501(transcript) - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:iZOqcqhEDT2q90EsGR+8S8Oef809606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P26196 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599139|imex:IM-26093-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P36957 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599139|imex:IM-26093-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P49756 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599139|imex:IM-26093-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:O14828 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599139|imex:IM-26093-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:C9JLW8 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-11599148|uniprotkb:Q6ZUL0|ensembl:ENSP00000409009|ensembl:ENSP00000445543|ensembl:ENSP00000458707|ensembl:ENSP00000458720|ensembl:ENSP00000499966|ensembl:ENSP00000500382|ensembl:ENSP00000500493|ensembl:ENSP00000500656 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:mcri1_human(display_long)|uniprotkb:MCRIP1(gene name)|psi-mi:MCRIP1(display_short)|uniprotkb:FAM195B(gene name synonym)|uniprotkb:GRAN2(gene name synonym)|uniprotkb:Granulin-2(gene name synonym)|uniprotkb:Protein FAM195B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599169|imex:IM-26093-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001087236.1|refseq:NP_997251.2|ensembl:ENST00000673154(transcript)|ensembl:ENST00000673369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|interpro:IPR029428|mint:C9JLW8|ensembl:ENSG00000225663(gene)|ensembl:ENSG00000288213(gene)|ensembl:ENST00000455127(transcript)|ensembl:ENST00000538396(transcript)|ensembl:ENST00000574190(transcript)|ensembl:ENST00000576730(transcript)|ensembl:ENST00000672201(transcript)|ensembl:ENST00000672501(transcript) - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:iZOqcqhEDT2q90EsGR+8S8Oef809606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P26196 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599169|imex:IM-26093-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P36957 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599169|imex:IM-26093-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:P49756 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599169|imex:IM-26093-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045598 uniprotkb:O14828 intact:EBI-6901421|intact:EBI-6928831 intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0 psi-mi:q99ib8-pro_0000045598(display_long) psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599169|imex:IM-26093-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1 - chain-seq-start:814|chain-seq-end:1030 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411 rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606 rigid:TmljUs/6+IQ5beVW0nELIBFXB4M false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q9Y3L5 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-2856617|uniprotkb:B3KWD6|uniprotkb:Q5H9H9|uniprotkb:Q9BTS0|ensembl:ENSP00000340274|ensembl:ENSP00000359911 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:rap2c_human(display_long)|uniprotkb:RAP2C(gene name)|psi-mi:RAP2C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:XP_011529678.1|refseq:NP_067006.3|refseq:NP_001258116.1|refseq:NP_001258115.1|ensembl:ENSG00000123728(gene)|ensembl:ENST00000342983(transcript)|ensembl:ENST00000370874(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0019003"(GDP binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|reactome:R-HSA-6798695 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:sJd/ACUSylvly87sdRNcZUiF91k9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:P57678 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:P05455 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q8N442 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-5460727|uniprotkb:Q5XKM8|uniprotkb:Q9H710|uniprotkb:Q9H8U4|ensembl:ENSP00000281543 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:guf1_human(display_long)|uniprotkb:GUF1(gene name)|psi-mi:GUF1(display_short)|uniprotkb:Elongation factor 4 homolog(gene name synonym)|uniprotkb:GTPase GUF1(gene name synonym)|uniprotkb:Ribosomal back-translocase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_068746.2|interpro:IPR031157|interpro:IPR035647|interpro:IPR035654|interpro:IPR038363|ensembl:ENSG00000151806(gene)|ensembl:ENST00000281543(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006297(GTP-binding protein LepA)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR013842(GTP-binding protein LepA, C-terminal)|interpro:IPR027417 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:8qGEN4UaBdf2SZbCrIzSU2qDugo9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q12904 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-1045802|uniprotkb:Q6FG28|uniprotkb:Q96CQ9|uniprotkb:B4E1S7|uniprotkb:B3KTR2|ensembl:ENSP00000350699|ensembl:ENSP00000499850|ensembl:ENSP00000499921|ensembl:ENSP00000500025|ensembl:ENSP00000500159|ensembl:ENSP00000500170|ensembl:ENSP00000500620|ensembl:ENSP00000500668|ensembl:ENSP00000500732|ensembl:ENSP00000500794 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:aimp1_human(display_long)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:SCYE1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001135887.1|refseq:NP_001135888.1|refseq:NP_004748.2|ensembl:ENSG00000164022(gene)|ensembl:ENST00000358008(transcript)|ensembl:ENST00000671868(transcript)|ensembl:ENST00000671960(transcript)|ensembl:ENST00000672285(transcript)|ensembl:ENST00000672328(transcript)|ensembl:ENST00000672337(transcript)|ensembl:ENST00000672341(transcript)|ensembl:ENST00000672911(transcript)|ensembl:ENST00000673018(transcript)|ensembl:ENST00000673123(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q12904|rcsb pdb:1E7Z|rcsb pdb:1EUJ|rcsb pdb:1FL0|rcsb pdb:4R3Z|reactome:R-HSA-2408522|reactome:R-HSA-379716|refseq:XP_016864324.1|refseq:XP_016864325.1 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:UtCeSRjFyuuEHUxVF2HkG9RA55k9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:P48556 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q9H4B7 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-2949748|ensembl:ENSP00000217133 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:tbb1_human(display_long)|uniprotkb:TUBB1(gene name)|psi-mi:TUBB1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000101162(gene)|ensembl:ENST00000217133(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0051225"(spindle assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9H4B7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-983189|reactome:R-HSA-9668328|refseq:NP_110400.1|dip:DIP-42487N - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:6bCGUsGUoUdlvvDkLH2G+2V3cdc9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:P63151 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q96KQ7 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:O15084 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q96J01 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-2510823|ensembl:ENSP00000265097|uniprotkb:Q6NZ53 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:thoc3_human(display_long)|uniprotkb:THOC3(gene name)|psi-mi:THOC3(display_short)|uniprotkb:TEX1 homolog(gene name synonym)|uniprotkb:hTREX45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000051596(gene)|ensembl:ENST00000265097(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|interpro:IPR040132|mint:Q96J01|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_115737.1 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:ENG6Gf3Q6WsTn5qkASarueRR+qc9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q9BZH6 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-2009923|uniprotkb:Q5VWA1|uniprotkb:Q9P2J6|ensembl:ENSP00000263461 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:wdr11_human(display_long)|uniprotkb:WDR11(gene name)|psi-mi:WDR11(display_short)|uniprotkb:KIAA1351(gene name synonym)|uniprotkb:BRWD2(gene name synonym)|uniprotkb:WDR15(gene name synonym)|uniprotkb:Bromodomain and WD repeat-containing protein 2(gene name synonym)|uniprotkb:WD repeat-containing protein 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_060587.8|ensembl:ENSG00000120008(gene)|ensembl:ENST00000263461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039694|mint:Q9BZH6|reactome:R-HSA-9013407 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:Kl337t8mCHvvkb8oi0z8Ohl72a09606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:O95071 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q16401 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-752143|uniprotkb:Q15045|uniprotkb:Q4VXG8|intact:EBI-10968906|uniprotkb:B4DZM8|ensembl:ENSP00000210313 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:psmd5_human(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:26S protease subunit S5 basic(gene name synonym)|uniprotkb:PSMD5(gene name)|psi-mi:PSMD5(display_short)|uniprotkb:KIAA0072(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_005038.1|refseq:NP_001257356.1|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000095261(gene)|ensembl:ENST00000210313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|mint:Q16401|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:XLVvCeWct98fvc6ktvaWNXwt9dE9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q9NRN7 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-740884|ensembl:ENSP00000278618|uniprotkb:Q9C068|uniprotkb:Q9P0Q3|uniprotkb:Q9UG80|uniprotkb:Q9Y389|uniprotkb:B2R6D1|uniprotkb:B4DDW7 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:adppt_human(display_long)|uniprotkb:4'-phosphopantetheinyl transferase(gene name synonym)|uniprotkb:Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase(gene name synonym)|uniprotkb:LYS5 ortholog(gene name synonym)|uniprotkb:AASDHPPT(gene name)|psi-mi:AASDHPPT(display_short)|uniprotkb:CGI-80(orf name)|uniprotkb:HAH-P(orf name)|uniprotkb:HSPC223(orf name)|uniprotkb:x0005(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_056238.2|ensembl:ENSG00000149313(gene)|ensembl:ENST00000278618(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008897"(holo-[acyl-carrier-protein] synthase activity)|go:"GO:0015939"(pantothenate metabolic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008278(4'-phosphopantetheinyl transferase)|interpro:IPR037143|rcsb pdb:2BYD|rcsb pdb:2C43|rcsb pdb:2CG5|reactome:R-HSA-199220 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:0S9gDK0HeJ+8eoM5vHaJDW3THAY9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q96JJ3 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-3959230|ensembl:ENSP00000290246|ensembl:ENSP00000379673|uniprotkb:Q9NQQ6|uniprotkb:Q5JVZ6|uniprotkb:E1P5T3|uniprotkb:Q9HAH0|uniprotkb:Q9H9L5|uniprotkb:Q9H938|uniprotkb:Q96PA9|uniprotkb:Q96CJ2|uniprotkb:Q96ME5|uniprotkb:Q7Z5G9 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:elmo2_human(display_long)|uniprotkb:ELMO2(gene name)|psi-mi:ELMO2(display_short)|uniprotkb:CED12A(gene name synonym)|uniprotkb:KIAA1834(gene name synonym)|uniprotkb:Protein ced-12 homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000062598(gene)|ensembl:ENST00000290246(transcript)|ensembl:ENST00000396391(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0048870"(cell motility)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR030713|rcsb pdb:6IDX|rcsb pdb:6IE1|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013408|reactome:R-HSA-9664422|refseq:NP_001305182.1|refseq:NP_573403.1|refseq:NP_877496.1|refseq:XP_005260553.1|refseq:XP_006723917.1|refseq:XP_005260555.1|refseq:XP_005260556.1|refseq:XP_005260557.1 - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:dXWjmEDxNMqr2k3/jdmSPB35MM49606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q9BV38 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599512|imex:IM-26093-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) - chain-seq-start:1031|chain-seq-end:1661 - figure legend:table s3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606 rigid:syu1Pw0sbOo3qJ2wTwRwlUjYIQY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P62834 intact:EBI-9096996 intact:EBI-491414|uniprotkb:P10113|ensembl:ENSP00000348786|ensembl:ENSP00000358723|intact:EBI-1047696 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:rap1a_human(display_long)|uniprotkb:GTP-binding protein smg p21A(gene name synonym)|uniprotkb:Ras-related protein Krev-1(gene name synonym)|uniprotkb:C21KG(gene name synonym)|uniprotkb:G-22K(gene name synonym)|uniprotkb:RAP1A(gene name)|psi-mi:RAP1A(display_short)|uniprotkb:KREV1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) go:"GO:0097421"(liver regeneration)|refseq:NP_001278825.1|refseq:NP_001010935.1|refseq:NP_002875.1|go:"GO:0035579"(specific granule membrane)|go:"GO:0035690"|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|ensembl:ENSG00000116473(gene)|ensembl:ENST00000356415(transcript)|ensembl:ENST00000369709(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010008"(endosome membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0030054"(cell junction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|rcsb pdb:1C1Y|rcsb pdb:1GUA|rcsb pdb:3KUC|rcsb pdb:4KVG|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8875555|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:XP_016857451.1|refseq:XP_016857452.1|refseq:XP_016857453.1|dip:DIP-29106N - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:QtjMjJiMQF0CbTD40IZgca4XfIU9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9NWW5 intact:EBI-9096996 intact:EBI-6165897|ensembl:ENSP00000249806|uniprotkb:B4DDH6|uniprotkb:A8K560|uniprotkb:Q6IAB1|uniprotkb:Q96SR0 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:cln6_human(display_long)|uniprotkb:CLN6(gene name)|psi-mi:CLN6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000128973(gene)|ensembl:ENST00000249806(transcript)|go:"GO:0001573"(ganglioside metabolic process)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007601"(visual perception)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044265"(cellular macromolecule catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0120146"(sulfatide binding)|interpro:IPR029255|refseq:NP_060352.1 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:oX9lqo/LjQbBWTpBj1voRRmnOO89606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9GZP9 intact:EBI-9096996 intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032 - chain-seq-start:1662|chain-seq-end:1715 comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation" figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:O95292 intact:EBI-9096996 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P05026 intact:EBI-9096996 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q6YN16 intact:EBI-9096996 intact:EBI-1056665|uniprotkb:A8K1L4|uniprotkb:A8K8X1|uniprotkb:A8MSV3|uniprotkb:Q658M8|uniprotkb:Q9BT58|ensembl:ENSP00000381785 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:hsdl2_human(display_long)|uniprotkb:HSDL2(gene name)|psi-mi:HSDL2(display_short)|uniprotkb:C9orf99(gene name synonym)|uniprotkb:SDR13C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 13C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001182751.1|refseq:NP_115679.2|ensembl:ENSG00000119471(gene)|ensembl:ENST00000398805(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR036291|interpro:IPR036527|rcsb pdb:3KVO - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:9p5t2957ZP6MwNTNgdfX0rUepnI9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q96NT5 intact:EBI-9096996 intact:EBI-4319513|uniprotkb:Q1HE20|uniprotkb:Q86T92|uniprotkb:Q8TEG3|uniprotkb:Q96FL0|ensembl:ENSP00000480703 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:pcft_human(display_long)|uniprotkb:HCP1(gene name synonym)|uniprotkb:PCFT(gene name synonym)|uniprotkb:G21(gene name synonym)|uniprotkb:Heme carrier protein 1(gene name synonym)|uniprotkb:PCFT/HCP1(gene name synonym)|uniprotkb:Solute carrier family 46 member 1(gene name synonym)|uniprotkb:SLC46A1(gene name)|psi-mi:SLC46A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001229295.1|refseq:NP_542400.2|ensembl:ENSG00000076351(gene)|ensembl:ENST00000612814(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008517"(folic acid transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015350"(methotrexate transmembrane transporter activity)|go:"GO:0015884"(folic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042168"(heme metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0051958"(methotrexate transport)|go:"GO:0098829"(intestinal folate absorption)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q96NT5|reactome:R-HSA-196757|reactome:R-HSA-917937|reactome:R-HSA-9707616 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:b0cJ4xSftwT+ZdfYSlp0ZSAol5g9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9P2W9 intact:EBI-9096996 intact:EBI-725334|uniprotkb:Q596L3|uniprotkb:Q5TZP5|ensembl:ENSP00000305810 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:stx18_human(display_long)|uniprotkb:Cell growth-inhibiting gene 9 protein(gene name synonym)|uniprotkb:STX18(gene name)|psi-mi:STX18(display_short)|uniprotkb:GIG9(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_058626.1|refseq:NP_001333211.1|refseq:NP_001333210.1|refseq:NP_001333229.1|ensembl:ENSG00000168818(gene)|ensembl:ENST00000306200(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1902117"(positive regulation of organelle assembly)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR019529|mint:Q9P2W9|reactome:R-HSA-6811434|dip:DIP-37617N - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:QpvkckDM1D5Jaty6AmK3vEwRZts9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q7LGA3 intact:EBI-9096996 intact:EBI-5461291|ensembl:ENSP00000359581|uniprotkb:D3DT22|uniprotkb:O75036|uniprotkb:Q32NB5|uniprotkb:Q8TAC5|uniprotkb:Q9H441|uniprotkb:Q9NUJ9 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:hs2st_human(display_long)|uniprotkb:HS2ST1(gene name)|psi-mi:HS2ST1(display_short)|uniprotkb:HS2ST(gene name synonym)|uniprotkb:KIAA0448(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000153936(gene)|ensembl:ENST00000370550(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004394"(heparan sulfate 2-O-sulfotransferase activity)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|mint:Q7LGA3|reactome:R-HSA-2022928|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|refseq:NP_001127964.1|refseq:NP_036394.1 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:96+iUitOmSLSpaEzhZu+9fZXLEQ9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q5GH72 intact:EBI-9096996 intact:EBI-11599587|uniprotkb:Q9NUG5|ensembl:ENSP00000477059 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:xkr7_human(display_long)|uniprotkb:XKR7(gene name)|psi-mi:XKR7(display_short)|uniprotkb:C20orf159(gene name synonym)|uniprotkb:XRG7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001011718.1|ensembl:ENSG00000260903(gene)|ensembl:ENST00000562532(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1902742"(apoptotic process involved in development)|interpro:IPR018629 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:36yb78C8p6CCmPNC8DM4GWLxe2A9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9UL46 intact:EBI-9096996 intact:EBI-741630|uniprotkb:Q15129|ensembl:ENSP00000216802|ensembl:ENSP00000495790 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:psme2_human(display_long)|uniprotkb:Proteasome activator 28 subunit beta(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 2(gene name synonym)|uniprotkb:11S regulator complex subunit beta(gene name synonym)|uniprotkb:PSME2(gene name)|psi-mi:PSME2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_002809.2|ensembl:ENSG00000100911(gene)|ensembl:ENSG00000284889(gene)|ensembl:ENST00000216802(transcript)|ensembl:ENST00000645325(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q9UL46|rcsb pdb:7DR6|rcsb pdb:7DRW|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-5678895|reactome:R-HSA-174178|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8950505|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:I1OweiKOkWYntSzrxcNfWjAHgx49606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P42167 intact:EBI-9096996 intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q92544 intact:EBI-9096996 intact:EBI-6138615|uniprotkb:B0QYT7|uniprotkb:Q9NUA3|ensembl:ENSP00000381104 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:tm9s4_human(display_long)|uniprotkb:TM9SF4(gene name)|psi-mi:TM9SF4(display_short)|uniprotkb:KIAA0255(gene name synonym)|uniprotkb:TUCAP1(gene name synonym)|uniprotkb:Tumor cannibalism associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_055557.2|refseq:XP_005260679.1|ensembl:ENSG00000101337(gene)|ensembl:ENST00000398022(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0072657"(protein localization to membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q92544 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:fyUWoncGmCxUAMx15iApsIcXdCI9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P04035 intact:EBI-9096996 intact:EBI-465513|uniprotkb:B7Z3Y9|uniprotkb:Q8N190|ensembl:ENSP00000287936|ensembl:ENSP00000426745|ensembl:ENSP00000505561|ensembl:ENSP00000505805|ensembl:ENSP00000506232 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:hmdh_human(display_long)|uniprotkb:HMGCR(gene name)|psi-mi:HMGCR(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_000850.1|refseq:NP_001124468.1|refseq:XP_011541659.1|refseq:XP_011541660.1|ensembl:ENSG00000113161(gene)|ensembl:ENST00000287936(transcript)|ensembl:ENST00000511206(transcript)|ensembl:ENST00000680940(transcript)|ensembl:ENST00000681271(transcript)|ensembl:ENST00000681410(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0006743"(ubiquinone metabolic process)|go:"GO:0007568"(aging)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070402"(NADPH binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR004816(Hydroxymethylglutaryl-CoA reductase, class I, metazoan)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|rcsb pdb:1DQ8|rcsb pdb:1DQ9|rcsb pdb:1DQA|rcsb pdb:1HW8|rcsb pdb:1HW9|rcsb pdb:1HWI|rcsb pdb:1HWJ|rcsb pdb:1HWK|rcsb pdb:1HWL|rcsb pdb:2Q1L|rcsb pdb:2Q6B|rcsb pdb:2Q6C|rcsb pdb:2R4F|rcsb pdb:3BGL|rcsb pdb:3CCT|rcsb pdb:3CCW|rcsb pdb:3CCZ|rcsb pdb:3CD0|rcsb pdb:3CD5|rcsb pdb:3CD7|rcsb pdb:3CDA|rcsb pdb:3CDB|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-9619665 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:fXmkDPv7ThH/PSLiNUgYR6hiIpY9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9UBV8 intact:EBI-9096996 intact:EBI-724639|ensembl:ENSP00000362807 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:pef1_human(display_long)|uniprotkb:PEF protein with a long N-terminal hydrophobic domain(gene name synonym)|uniprotkb:Penta-EF hand domain-containing protein 1(gene name synonym)|uniprotkb:PEF1(gene name)|psi-mi:PEF1(display_short)|uniprotkb:ABP32(gene name synonym)|uniprotkb:UNQ1845/PRO3573(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_036524.1|ensembl:ENSG00000162517(gene)|ensembl:ENST00000373703(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0003723"(RNA binding)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBV8 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:HoQa0GPucZdIv5g9+OoHdanlyPo9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 intact:EBI-25401924 intact:EBI-9096996 - psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:rs4x_rs4y1_rs4y2_human(display_short)|psi-mi:EBI-25401924(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) intact:EBI-6674379(chain-parent) - - chain-seq-start:1662|chain-seq-end:1715 comment:P22090,P62701,Q8TD47 figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 - - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:O96005 intact:EBI-9096996 intact:EBI-2873194|ensembl:ENSP00000336994|uniprotkb:Q53ET6|uniprotkb:Q9BSS5|uniprotkb:B3KQH2|uniprotkb:B4DDS3|uniprotkb:B4E2X9|uniprotkb:B7Z9X9|uniprotkb:F5H8J3 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:clpt1_human(display_long)|uniprotkb:CLPTM1(gene name)|psi-mi:CLPTM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000104853(gene)|ensembl:ENST00000337392(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:O96005|refseq:NP_001285.1|refseq:NP_001269104.1|refseq:NP_001269105.1 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:CFQ2o5QzCYtIDaxlVtJlA6FEMgU9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9BRX8 intact:EBI-9096996 intact:EBI-4399402|uniprotkb:B2RD81|uniprotkb:Q6UW08|uniprotkb:Q8N2K3|uniprotkb:Q8NBK9|uniprotkb:Q96JR0|ensembl:ENSP00000361254|ensembl:ENSP00000361261|ensembl:ENSP00000361262|ensembl:ENSP00000478152|ensembl:ENSP00000482445 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:pxl2a_human(display_long)|uniprotkb:C10orf58(gene name synonym)|uniprotkb:PAMM(gene name synonym)|uniprotkb:Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes(gene name synonym)|uniprotkb:PRXL2A(gene name)|psi-mi:PRXL2A(display_short)|uniprotkb:FAM213A(gene name synonym)|uniprotkb:Redox-regulatory protein FAM213A(gene name synonym)|uniprotkb:PRO2290(orf name)|uniprotkb:PSEC0139(orf name)|uniprotkb:UNQ611/PRO1198(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_115709.3|refseq:NP_001230707.1|refseq:NP_001230708.1|refseq:NP_001230709.1|refseq:NP_001230710.1|refseq:XP_011538567.1|refseq:XP_011538568.1|refseq:NP_001230711.1|ensembl:ENSG00000122378(gene)|ensembl:ENST00000372181(transcript)|ensembl:ENST00000372187(transcript)|ensembl:ENST00000372188(transcript)|ensembl:ENST00000606162(transcript)|ensembl:ENST00000615554(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016209"(antioxidant activity)|go:"GO:0045670"(regulation of osteoclast differentiation)|interpro:IPR032801|interpro:IPR032802|mint:Q9BRX8 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:qAvv/5+5HfPHe6kqNCdbmDQvvMw9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P01111 intact:EBI-9096996 intact:EBI-721993|uniprotkb:Q14971|uniprotkb:Q15104|uniprotkb:Q15282|ensembl:ENSP00000358548 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:rasn_human(display_long)|uniprotkb:Transforming protein N-Ras(gene name synonym)|uniprotkb:NRAS(gene name)|psi-mi:NRAS(display_short)|uniprotkb:HRAS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_002515.1|ensembl:ENSG00000213281(gene)|ensembl:ENST00000369535(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|interpro:IPR001806(Ras GTPase)|dip:DIP-1058N|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01111|rcsb pdb:2N9C|rcsb pdb:3CON|rcsb pdb:5UHV|rcsb pdb:6E6H|rcsb pdb:6MPP|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6WGH|rcsb pdb:6ZIO|rcsb pdb:6ZIR|rcsb pdb:6ZIZ|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:Et90BD+t6LnYThbW6ShQge1GRK89606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9NVJ2 intact:EBI-9096996 intact:EBI-718376|uniprotkb:B4DI85|ensembl:ENSP00000256496 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:arl8b_human(display_long)|uniprotkb:ADP-ribosylation factor-like protein 10C(gene name synonym)|uniprotkb:Novel small G protein indispensable for equal chromosome segregation 1(gene name synonym)|uniprotkb:ARL8B(gene name)|psi-mi:ARL8B(display_short)|uniprotkb:ARL10C(gene name synonym)|uniprotkb:GIE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_060654.1|ensembl:ENSG00000134108(gene)|ensembl:ENST00000256496(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002505"(antigen processing and presentation of polysaccharide antigen via MHC class II)|go:"GO:0002747"(antigen processing and presentation following phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032418"(lysosome localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045202"(synapse)|go:"GO:0046754"(viral exocytosis)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090117"(endosome to lysosome transport of low-density lipoprotein particle)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990927"(calcium ion regulated lysosome exocytosis)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|go:"GO:0031902"(late endosome membrane)|interpro:IPR044154|mint:Q9NVJ2|rcsb pdb:2AL7 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:DLTh63yjvilHei1RUU6P4Ad0TAo9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P02760 intact:EBI-9096996 intact:EBI-2115136|uniprotkb:P00977|uniprotkb:P02759|uniprotkb:P78491|uniprotkb:Q2TU33|uniprotkb:Q5TBD7|uniprotkb:Q9UC58|uniprotkb:Q9UDI8|ensembl:ENSP00000265132 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:ambp_human(display_long)|uniprotkb:AMBP(gene name)|psi-mi:AMBP(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:ITIL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001624.1|ensembl:ENSG00000106927(gene)|ensembl:ENST00000265132(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007565"(female pregnancy)|go:"GO:0009986"(cell surface)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019862"(IgA binding)|go:"GO:0020037"(heme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046904"(calcium oxalate binding)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR002968(Alpha-1-microglobulin)|interpro:IPR012674(Calycin)|interpro:IPR020901|interpro:IPR022272|interpro:IPR029856|interpro:IPR036880|rcsb pdb:1BIK|rcsb pdb:3QKG|rcsb pdb:4ES7|rcsb pdb:4U30|rcsb pdb:6EJ7|rcsb pdb:6EJ8|rcsb pdb:6EJ9|rcsb pdb:6EJA|rcsb pdb:6EJB|rcsb pdb:6EJC|rcsb pdb:6EJD|reactome:R-HSA-2168880 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:os91tgT4TUMZ1qCf3SRbW5mwlGI9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P02649 intact:EBI-9096996 intact:EBI-1222467|uniprotkb:C0JYY5|uniprotkb:Q9P2S4|uniprotkb:B2RC15|ensembl:ENSP00000252486 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:apoe_human(display_long)|uniprotkb:APOE(gene name)|psi-mi:APOE(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_000032.1|refseq:NP_001289617.1|refseq:NP_001289618.1|refseq:NP_001289619.1|refseq:NP_001289620.1|dip:DIP-1120N|ensembl:ENSG00000130203(gene)|ensembl:ENST00000252486(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010467"(gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046907"(intracellular transport)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072562"(blood microparticle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901627"(negative regulation of postsynaptic membrane organization)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1902999"(negative regulation of phospholipid efflux)|go:"GO:1903001"(negative regulation of lipid transport across blood-brain barrier)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02649|rcsb pdb:1B68|rcsb pdb:1BZ4|rcsb pdb:1EA8|rcsb pdb:1GS9|rcsb pdb:1H7I|rcsb pdb:1LE2|rcsb pdb:1LE4|rcsb pdb:1LPE|rcsb pdb:1NFN|rcsb pdb:1NFO|rcsb pdb:1OEF|rcsb pdb:1OEG|rcsb pdb:1OR2|rcsb pdb:1OR3|rcsb pdb:2KC3|rcsb pdb:2KNY|rcsb pdb:2L7B|rcsb pdb:6IWB|rcsb pdb:6NCN|rcsb pdb:6NCO|reactome:R-HSA-1251985|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-8864260|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964058|reactome:R-HSA-9029569|reactome:R-HSA-975634|reactome:R-HSA-977225 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:vnCU03+HdGblqtALKeOTZRx5/3E9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P38435 intact:EBI-9096996 intact:EBI-10963113|ensembl:ENSP00000233838|uniprotkb:B4DMC5|uniprotkb:E9PEE1|uniprotkb:Q6GU45|uniprotkb:Q14415 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:vkgc_human(display_long)|uniprotkb:GGCX(gene name)|psi-mi:GGCX(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:Gamma-glutamyl carboxylase(gene name synonym)|uniprotkb:Peptidyl-glutamate 4-carboxylase(gene name synonym)|uniprotkb:Vitamin K gamma glutamyl carboxylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_000812.2|refseq:NP_001135741.1|ensembl:ENSG00000115486(gene)|ensembl:ENST00000233838(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007596"(blood coagulation)|go:"GO:0008488"(gamma-glutamyl carboxylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0019842"(vitamin binding)|interpro:IPR007782(Vitamin K-dependent gamma-carboxylase)|interpro:IPR011020(HTTM)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|mint:P38435|reactome:R-HSA-159740|reactome:R-HSA-9673240 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:icDLv1KyH9HC3h9enCp9S/nXPmM9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P13929 intact:EBI-9096996 intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging) - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P60604 intact:EBI-9096996 intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9BU23 intact:EBI-9096996 intact:EBI-10298556|uniprotkb:Q96C62|uniprotkb:Q13392|uniprotkb:Q8WU74|uniprotkb:Q6ZNR2|uniprotkb:A6NEZ0|ensembl:ENSP00000424381 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:lmf2_human(display_long)|uniprotkb:LMF2(gene name)|psi-mi:LMF2(display_short)|uniprotkb:TMEM112B(gene name synonym)|uniprotkb:TMEM153(gene name synonym)|uniprotkb:Transmembrane protein 112B(gene name synonym)|uniprotkb:Transmembrane protein 153(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_149977.2|refseq:XP_005262012.1|ensembl:ENSG00000100258(gene)|ensembl:ENST00000474879(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051604"(protein maturation)|interpro:IPR009613(Protein of unknown function DUF1222)|reactome:R-HSA-8963889 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:xI+AYnn8Oj5BWzpTBzJi4K83wck9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q96A83 intact:EBI-9096996 intact:EBI-949928|uniprotkb:Q32M90|ensembl:ENSP00000318234 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:coqa1_human(display_long)|uniprotkb:COL26A1(gene name)|psi-mi:COL26A1(display_short)|uniprotkb:Alpha-1 type XXVI collagen(gene name synonym)|uniprotkb:EMI domain-containing protein 2(gene name synonym)|uniprotkb:EMID2(gene name synonym)|uniprotkb:EMU2(gene name synonym)|uniprotkb:Emilin and multimerin domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_597714.2|refseq:NP_001265492.1|ensembl:ENSG00000160963(gene)|ensembl:ENST00000313669(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR011489(EMI)|rcsb pdb:4AU2|rcsb pdb:4AU3|rcsb pdb:4BJ3|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-8948216 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:GRkWcz27NHOYiam00t3hUUVs2ks9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9NTJ5 intact:EBI-9096996 intact:EBI-3917235|uniprotkb:B4DK71|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713|ensembl:ENSP00000500361 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:XP_011531802.1|refseq:NP_054735.3|refseq:NP_001306001.1|refseq:NP_001306002.1|ensembl:ENSG00000211456(gene)|ensembl:ENST00000389061(transcript)|ensembl:ENST00000672477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016791"(phosphatase activity) - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:P98194 intact:EBI-9096996 intact:EBI-2939877|ensembl:ENSP00000395809|ensembl:ENSP00000424783|ensembl:ENSP00000427461|uniprotkb:B2RAT7|uniprotkb:O76005|uniprotkb:Q86V72|uniprotkb:Q86V73|uniprotkb:Q8N6V1|uniprotkb:Q8NCJ7|uniprotkb:B4DSW3|uniprotkb:B7Z3X9|uniprotkb:G3XAH8|uniprotkb:G8JLN9 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:at2c1_human(display_long)|uniprotkb:ATP2C1(gene name)|psi-mi:ATP2C1(display_short)|uniprotkb:KIAA1347(gene name synonym)|uniprotkb:PMR1L(gene name synonym)|uniprotkb:"ATP-dependent Ca(2+) pump PMR1"(gene name synonym)|uniprotkb:"Ca(2+)/Mn(2+)-ATPase 2C1"(gene name synonym)|uniprotkb:"Secretory pathway Ca(2+)-transporting ATPase type 1"(gene name synonym)|uniprotkb:HUSSY-28(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000017260(gene)|ensembl:ENST00000428331(transcript)|ensembl:ENST00000508532(transcript)|ensembl:ENST00000510168(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0015410"(ABC-type manganese transporter activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032468"(Golgi calcium ion homeostasis)|go:"GO:0032472"(Golgi calcium ion transport)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098629"(trans-Golgi network membrane organization)|go:"GO:0140613"(P-type manganese transporter activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006413(Calcium-transporting P-type ATPase, PMR1-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030336|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837|refseq:NP_001001485.1|refseq:NP_001001486.1|refseq:NP_001001487.1|refseq:NP_001186108.1|refseq:NP_001186109.1|refseq:NP_001186110.1|refseq:NP_001186111.1|refseq:NP_001186112.1|refseq:NP_001186113.1|refseq:NP_001186114.1|refseq:NP_055197.2|refseq:XP_016861653.1|refseq:XP_005247412.1|refseq:XP_005247413.1 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:jPAb8dnATDdbBvc++3El2w2Zaeg9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9P0L0 intact:EBI-9096996 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045600 uniprotkb:Q9UGP8 intact:EBI-9096996 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599534|imex:IM-26093-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1 - chain-seq-start:1662|chain-seq-end:1715 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2021/09/28 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 - false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P00846 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1389380|uniprotkb:Q34772|uniprotkb:Q5S8W5|uniprotkb:Q5S9E7|uniprotkb:Q5S9I6|uniprotkb:Q5SA31|uniprotkb:Q6RPB7|uniprotkb:Q6VHC0|uniprotkb:Q6VHE0|uniprotkb:Q6WQF4|uniprotkb:Q7YCC1|uniprotkb:Q7YCF8|uniprotkb:Q7YCG1|uniprotkb:Q85KU8|uniprotkb:Q85KX1|uniprotkb:Q85L05|uniprotkb:Q8HNQ4|uniprotkb:Q8HNQ8|uniprotkb:Q8WCX6|uniprotkb:Q9B2U5|uniprotkb:Q9B2Z2|ensembl:ENSP00000354632 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:atp6_human(display_long)|uniprotkb:MT-ATP6(gene name)|psi-mi:MT-ATP6(display_short)|uniprotkb:ATP6(gene name synonym)|uniprotkb:ATPASE6(gene name synonym)|uniprotkb:MTATP6(gene name synonym)|uniprotkb:F-ATPase protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:YP_003024031.1|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0055093"(response to hyperoxia)|interpro:IPR000568(ATPase, F0 complex, subunit A)|interpro:IPR023011|interpro:IPR035908|mint:P00846|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000198899(gene)|ensembl:ENST00000361899(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0007568"(aging)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:XGt0uP3ldTsWyNSOEiT5kDR5kOw9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O43169 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O95197 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-740467|intact:EBI-28977804|ensembl:ENSP00000367050|uniprotkb:Q147U9|uniprotkb:Q496K2|uniprotkb:Q53GN3|uniprotkb:Q59EP0|uniprotkb:Q5UEP2|uniprotkb:Q6T930|uniprotkb:Q7RTM7|uniprotkb:Q7RTM8|uniprotkb:Q7RTN3|uniprotkb:B3KQS2|uniprotkb:B7Z308|intact:EBI-11081390|uniprotkb:B7Z4M0|uniprotkb:F5H774 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:rtn3_human(display_long)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001252518.1|refseq:NP_006045.1|refseq:NP_958831.1|refseq:NP_958832.1|refseq:NP_958833.1|ensembl:ENSG00000133318(gene)|ensembl:ENST00000377819(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:O95197|rcsb pdb:7BRU|reactome:R-HSA-8849932|ensembl:ENSP00000348279|ensembl:ENSP00000367050|ensembl:ENST00000537981|ensembl:ENSP00000440874|ensembl:ENST00000540798|ensembl:ENSP00000442733|ensembl:ENST00000339997|ensembl:ENSP00000344106|ensembl:ENST00000341307|ensembl:ENSP00000340903|ensembl:ENST00000354497|ensembl:ENSP00000346492|ensembl:ENST00000356000|refseq:NP_001252519.1|refseq:NP_001252520.1 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:nlwcgOle9rsXe2uha2//mQlB4Do9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P23434 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-715444|uniprotkb:Q9H1E9|ensembl:ENSP00000319531 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:gcsh_human(display_long)|uniprotkb:GCSH(gene name)|psi-mi:GCSH(display_short)|uniprotkb:Lipoic acid-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004474.2|ensembl:ENSG00000140905(gene)|ensembl:ENST00000315467(transcript)|go:"GO:0004047"(aminomethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR002930(Glycine cleavage H-protein)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR011053(Single hybrid motif)|interpro:IPR017453(Glycine cleavage H-protein, subgroup)|interpro:IPR033753|reactome:R-HSA-389661|reactome:R-HSA-6783984 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:nLJNFRTAFkKpiUaXqnh5cGvCl5E9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P26196 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P50895 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-10212133|uniprotkb:A8MYF9|uniprotkb:Q86VC7|uniprotkb:A9YWT6|uniprotkb:A9YWT5|ensembl:ENSP00000270233 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:bcam_human(display_long)|uniprotkb:BCAM(gene name)|psi-mi:BCAM(display_short)|uniprotkb:Auberger B antigen(gene name synonym)|uniprotkb:B-CAM cell surface glycoprotein(gene name synonym)|uniprotkb:F8/G253 antigen(gene name synonym)|uniprotkb:LU(gene name synonym)|uniprotkb:Lutheran antigen(gene name synonym)|uniprotkb:Lutheran blood group glycoprotein(gene name synonym)|uniprotkb:MSK19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001013275.1|refseq:NP_005572.2|ensembl:ENSG00000187244(gene)|ensembl:ENST00000270233(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0043236"(laminin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2PET|rcsb pdb:2PF6 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:x0+dyVBq4nocOVEnSdGdWpXqpx89606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:Q8N456 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-751373|uniprotkb:Q6UY02|ensembl:ENSP00000363275 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:lrc18_human(display_long)|uniprotkb:LRRC18(gene name)|psi-mi:LRRC18(display_short)|uniprotkb:UNQ9338/PRO34010(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599610|imex:IM-26093-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001006940.3|refseq:XP_011538124.1|refseq:XP_011538125.1|refseq:XP_011538128.1|refseq:XP_011538130.1|refseq:XP_011538131.1|refseq:XP_006717930.1|refseq:XP_016871765.1|refseq:XP_016871766.1|ensembl:ENSG00000165383(gene)|ensembl:ENST00000374160(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:gKc5evWyzPYpUr8KIzDu4I9Oy4A9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P00846 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1389380|uniprotkb:Q34772|uniprotkb:Q5S8W5|uniprotkb:Q5S9E7|uniprotkb:Q5S9I6|uniprotkb:Q5SA31|uniprotkb:Q6RPB7|uniprotkb:Q6VHC0|uniprotkb:Q6VHE0|uniprotkb:Q6WQF4|uniprotkb:Q7YCC1|uniprotkb:Q7YCF8|uniprotkb:Q7YCG1|uniprotkb:Q85KU8|uniprotkb:Q85KX1|uniprotkb:Q85L05|uniprotkb:Q8HNQ4|uniprotkb:Q8HNQ8|uniprotkb:Q8WCX6|uniprotkb:Q9B2U5|uniprotkb:Q9B2Z2|ensembl:ENSP00000354632 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:atp6_human(display_long)|uniprotkb:MT-ATP6(gene name)|psi-mi:MT-ATP6(display_short)|uniprotkb:ATP6(gene name synonym)|uniprotkb:ATPASE6(gene name synonym)|uniprotkb:MTATP6(gene name synonym)|uniprotkb:F-ATPase protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:YP_003024031.1|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0055093"(response to hyperoxia)|interpro:IPR000568(ATPase, F0 complex, subunit A)|interpro:IPR023011|interpro:IPR035908|mint:P00846|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000198899(gene)|ensembl:ENST00000361899(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0007568"(aging)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:XGt0uP3ldTsWyNSOEiT5kDR5kOw9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O43169 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O95197 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-740467|intact:EBI-28977804|ensembl:ENSP00000367050|uniprotkb:Q147U9|uniprotkb:Q496K2|uniprotkb:Q53GN3|uniprotkb:Q59EP0|uniprotkb:Q5UEP2|uniprotkb:Q6T930|uniprotkb:Q7RTM7|uniprotkb:Q7RTM8|uniprotkb:Q7RTN3|uniprotkb:B3KQS2|uniprotkb:B7Z308|intact:EBI-11081390|uniprotkb:B7Z4M0|uniprotkb:F5H774 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:rtn3_human(display_long)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001252518.1|refseq:NP_006045.1|refseq:NP_958831.1|refseq:NP_958832.1|refseq:NP_958833.1|ensembl:ENSG00000133318(gene)|ensembl:ENST00000377819(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:O95197|rcsb pdb:7BRU|reactome:R-HSA-8849932|ensembl:ENSP00000348279|ensembl:ENSP00000367050|ensembl:ENST00000537981|ensembl:ENSP00000440874|ensembl:ENST00000540798|ensembl:ENSP00000442733|ensembl:ENST00000339997|ensembl:ENSP00000344106|ensembl:ENST00000341307|ensembl:ENSP00000340903|ensembl:ENST00000354497|ensembl:ENSP00000346492|ensembl:ENST00000356000|refseq:NP_001252519.1|refseq:NP_001252520.1 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:nlwcgOle9rsXe2uha2//mQlB4Do9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P23434 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-715444|uniprotkb:Q9H1E9|ensembl:ENSP00000319531 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:gcsh_human(display_long)|uniprotkb:GCSH(gene name)|psi-mi:GCSH(display_short)|uniprotkb:Lipoic acid-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004474.2|ensembl:ENSG00000140905(gene)|ensembl:ENST00000315467(transcript)|go:"GO:0004047"(aminomethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR002930(Glycine cleavage H-protein)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR011053(Single hybrid motif)|interpro:IPR017453(Glycine cleavage H-protein, subgroup)|interpro:IPR033753|reactome:R-HSA-389661|reactome:R-HSA-6783984 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:nLJNFRTAFkKpiUaXqnh5cGvCl5E9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P26196 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P50895 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-10212133|uniprotkb:A8MYF9|uniprotkb:Q86VC7|uniprotkb:A9YWT6|uniprotkb:A9YWT5|ensembl:ENSP00000270233 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:bcam_human(display_long)|uniprotkb:BCAM(gene name)|psi-mi:BCAM(display_short)|uniprotkb:Auberger B antigen(gene name synonym)|uniprotkb:B-CAM cell surface glycoprotein(gene name synonym)|uniprotkb:F8/G253 antigen(gene name synonym)|uniprotkb:LU(gene name synonym)|uniprotkb:Lutheran antigen(gene name synonym)|uniprotkb:Lutheran blood group glycoprotein(gene name synonym)|uniprotkb:MSK19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001013275.1|refseq:NP_005572.2|ensembl:ENSG00000187244(gene)|ensembl:ENST00000270233(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0043236"(laminin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2PET|rcsb pdb:2PF6 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:x0+dyVBq4nocOVEnSdGdWpXqpx89606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:Q8N456 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-751373|uniprotkb:Q6UY02|ensembl:ENSP00000363275 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:lrc18_human(display_long)|uniprotkb:LRRC18(gene name)|psi-mi:LRRC18(display_short)|uniprotkb:UNQ9338/PRO34010(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599622|imex:IM-26093-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001006940.3|refseq:XP_011538124.1|refseq:XP_011538125.1|refseq:XP_011538128.1|refseq:XP_011538130.1|refseq:XP_011538131.1|refseq:XP_006717930.1|refseq:XP_016871765.1|refseq:XP_016871766.1|ensembl:ENSG00000165383(gene)|ensembl:ENST00000374160(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:gKc5evWyzPYpUr8KIzDu4I9Oy4A9606 rigid:wtl3DkkACxJPAatI+jJYxaGo90s false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P00846 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1389380|uniprotkb:Q34772|uniprotkb:Q5S8W5|uniprotkb:Q5S9E7|uniprotkb:Q5S9I6|uniprotkb:Q5SA31|uniprotkb:Q6RPB7|uniprotkb:Q6VHC0|uniprotkb:Q6VHE0|uniprotkb:Q6WQF4|uniprotkb:Q7YCC1|uniprotkb:Q7YCF8|uniprotkb:Q7YCG1|uniprotkb:Q85KU8|uniprotkb:Q85KX1|uniprotkb:Q85L05|uniprotkb:Q8HNQ4|uniprotkb:Q8HNQ8|uniprotkb:Q8WCX6|uniprotkb:Q9B2U5|uniprotkb:Q9B2Z2|ensembl:ENSP00000354632 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:atp6_human(display_long)|uniprotkb:MT-ATP6(gene name)|psi-mi:MT-ATP6(display_short)|uniprotkb:ATP6(gene name synonym)|uniprotkb:ATPASE6(gene name synonym)|uniprotkb:MTATP6(gene name synonym)|uniprotkb:F-ATPase protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599634|imex:IM-26093-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:YP_003024031.1|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0055093"(response to hyperoxia)|interpro:IPR000568(ATPase, F0 complex, subunit A)|interpro:IPR023011|interpro:IPR035908|mint:P00846|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000198899(gene)|ensembl:ENST00000361899(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0007568"(aging)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:XGt0uP3ldTsWyNSOEiT5kDR5kOw9606 rigid:sVIU7eJ5sVHBNLMfYqEYrwLujBM false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O43169 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599634|imex:IM-26093-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:sVIU7eJ5sVHBNLMfYqEYrwLujBM false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O95197 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-740467|intact:EBI-28977804|ensembl:ENSP00000367050|uniprotkb:Q147U9|uniprotkb:Q496K2|uniprotkb:Q53GN3|uniprotkb:Q59EP0|uniprotkb:Q5UEP2|uniprotkb:Q6T930|uniprotkb:Q7RTM7|uniprotkb:Q7RTM8|uniprotkb:Q7RTN3|uniprotkb:B3KQS2|uniprotkb:B7Z308|intact:EBI-11081390|uniprotkb:B7Z4M0|uniprotkb:F5H774 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:rtn3_human(display_long)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599634|imex:IM-26093-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001252518.1|refseq:NP_006045.1|refseq:NP_958831.1|refseq:NP_958832.1|refseq:NP_958833.1|ensembl:ENSG00000133318(gene)|ensembl:ENST00000377819(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:O95197|rcsb pdb:7BRU|reactome:R-HSA-8849932|ensembl:ENSP00000348279|ensembl:ENSP00000367050|ensembl:ENST00000537981|ensembl:ENSP00000440874|ensembl:ENST00000540798|ensembl:ENSP00000442733|ensembl:ENST00000339997|ensembl:ENSP00000344106|ensembl:ENST00000341307|ensembl:ENSP00000340903|ensembl:ENST00000354497|ensembl:ENSP00000346492|ensembl:ENST00000356000|refseq:NP_001252519.1|refseq:NP_001252520.1 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:nlwcgOle9rsXe2uha2//mQlB4Do9606 rigid:sVIU7eJ5sVHBNLMfYqEYrwLujBM false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:P00846 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1389380|uniprotkb:Q34772|uniprotkb:Q5S8W5|uniprotkb:Q5S9E7|uniprotkb:Q5S9I6|uniprotkb:Q5SA31|uniprotkb:Q6RPB7|uniprotkb:Q6VHC0|uniprotkb:Q6VHE0|uniprotkb:Q6WQF4|uniprotkb:Q7YCC1|uniprotkb:Q7YCF8|uniprotkb:Q7YCG1|uniprotkb:Q85KU8|uniprotkb:Q85KX1|uniprotkb:Q85L05|uniprotkb:Q8HNQ4|uniprotkb:Q8HNQ8|uniprotkb:Q8WCX6|uniprotkb:Q9B2U5|uniprotkb:Q9B2Z2|ensembl:ENSP00000354632 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:atp6_human(display_long)|uniprotkb:MT-ATP6(gene name)|psi-mi:MT-ATP6(display_short)|uniprotkb:ATP6(gene name synonym)|uniprotkb:ATPASE6(gene name synonym)|uniprotkb:MTATP6(gene name synonym)|uniprotkb:F-ATPase protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599642|imex:IM-26093-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:YP_003024031.1|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0055093"(response to hyperoxia)|interpro:IPR000568(ATPase, F0 complex, subunit A)|interpro:IPR023011|interpro:IPR035908|mint:P00846|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000198899(gene)|ensembl:ENST00000361899(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0007568"(aging)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:XGt0uP3ldTsWyNSOEiT5kDR5kOw9606 rigid:sVIU7eJ5sVHBNLMfYqEYrwLujBM false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O43169 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599642|imex:IM-26093-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:sVIU7eJ5sVHBNLMfYqEYrwLujBM false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O95197 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-740467|intact:EBI-28977804|ensembl:ENSP00000367050|uniprotkb:Q147U9|uniprotkb:Q496K2|uniprotkb:Q53GN3|uniprotkb:Q59EP0|uniprotkb:Q5UEP2|uniprotkb:Q6T930|uniprotkb:Q7RTM7|uniprotkb:Q7RTM8|uniprotkb:Q7RTN3|uniprotkb:B3KQS2|uniprotkb:B7Z308|intact:EBI-11081390|uniprotkb:B7Z4M0|uniprotkb:F5H774 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:rtn3_human(display_long)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599642|imex:IM-26093-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001252518.1|refseq:NP_006045.1|refseq:NP_958831.1|refseq:NP_958832.1|refseq:NP_958833.1|ensembl:ENSG00000133318(gene)|ensembl:ENST00000377819(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:O95197|rcsb pdb:7BRU|reactome:R-HSA-8849932|ensembl:ENSP00000348279|ensembl:ENSP00000367050|ensembl:ENST00000537981|ensembl:ENSP00000440874|ensembl:ENST00000540798|ensembl:ENSP00000442733|ensembl:ENST00000339997|ensembl:ENSP00000344106|ensembl:ENST00000341307|ensembl:ENSP00000340903|ensembl:ENST00000354497|ensembl:ENSP00000346492|ensembl:ENST00000356000|refseq:NP_001252519.1|refseq:NP_001252520.1 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:nlwcgOle9rsXe2uha2//mQlB4Do9606 rigid:sVIU7eJ5sVHBNLMfYqEYrwLujBM false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:P12259 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-9640912|uniprotkb:A8K6E8|uniprotkb:Q14285|uniprotkb:Q5R346|uniprotkb:Q8WWQ6|uniprotkb:Q6UPU6|uniprotkb:Q2EHR5|uniprotkb:Q5R347|ensembl:ENSP00000356771 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:fa5_human(display_long)|uniprotkb:F5(gene name)|psi-mi:F5(display_short)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_000121.2|dip:DIP-47331N|ensembl:ENSG00000198734(gene)|ensembl:ENST00000367797(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009271(Coagulation factor V LSPD)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR024715|interpro:IPR033138|mint:P12259|rcsb pdb:1CZS|rcsb pdb:1CZT|rcsb pdb:1CZV|rcsb pdb:1FV4|rcsb pdb:1Y61|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3S9C|rcsb pdb:7KVE|rcsb pdb:7KVF|rcsb pdb:7KXY|reactome:R-HSA-114608|reactome:R-HSA-140875|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:i1+4mzlwzNvSHZ2CketeTEvnJEQ9606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O94966 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2511895|ensembl:ENSP00000381863|uniprotkb:Q641Q9|uniprotkb:Q86XV9|uniprotkb:Q3KQW4|uniprotkb:A6H8U2|uniprotkb:Q6NZY8|uniprotkb:A5PKX8|uniprotkb:B4DGT3|uniprotkb:E7ETS0|uniprotkb:E9PEG8|uniprotkb:B4DTZ0|uniprotkb:E7EN22 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ubp19_human(display_long)|uniprotkb:USP19(gene name)|psi-mi:USP19(display_short)|uniprotkb:KIAA0891(gene name synonym)|uniprotkb:ZMYND9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 19(gene name synonym)|uniprotkb:Deubiquitinating enzyme 19(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 9(gene name synonym)|uniprotkb:Ubiquitin thioesterase 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000172046(gene)|ensembl:ENST00000398888(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904292"(regulation of ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O94966|rcsb pdb:1WH0|rcsb pdb:4X3G|rcsb pdb:6K7W|rcsb pdb:6KHV|rcsb pdb:6KQV|reactome:R-HSA-5689880|refseq:NP_001186089.1|refseq:NP_001186090.1|refseq:NP_001186091.1|refseq:NP_006668.1|refseq:XP_005264888.1|refseq:XP_016861115.1|refseq:XP_016861122.1 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:5U3FuLQ44MsWtu7o/3bY7seGC3M9606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O00499 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q04837 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q8NBS9 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q7RTV0 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:P22455 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-6256193|uniprotkb:G3JVM2|uniprotkb:G3JVM5|uniprotkb:G3JVM7|uniprotkb:G3JVM9|uniprotkb:Q96KE5|ensembl:ENSP00000292408|ensembl:ENSP00000424960|uniprotkb:O43785|uniprotkb:Q14309|uniprotkb:Q71TW8|uniprotkb:Q8TDA0 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:fgfr4_human(display_long)|uniprotkb:FGFR4(gene name)|psi-mi:FGFR4(display_short)|uniprotkb:JTK2(gene name synonym)|uniprotkb:TKF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001278909.1|ensembl:ENSG00000160867(gene)|ensembl:ENST00000292408(transcript)|ensembl:ENST00000502906(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030133"(transport vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055062"(phosphate ion homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR016248(Fibroblast growth factor receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|mint:P22455|rcsb pdb:1QCT|rcsb pdb:4QQ5|rcsb pdb:4QQC|rcsb pdb:4QQJ|rcsb pdb:4QQT|rcsb pdb:4QRC|rcsb pdb:4R6V|rcsb pdb:4TYE|rcsb pdb:4TYG|rcsb pdb:4TYI|rcsb pdb:4UXQ|rcsb pdb:4XCU|rcsb pdb:5JKG|rcsb pdb:5NUD|rcsb pdb:5NWZ|rcsb pdb:5XFF|rcsb pdb:5XFJ|rcsb pdb:6IUO|rcsb pdb:6IUP|rcsb pdb:6J6Y|rcsb pdb:6JPE|rcsb pdb:6JPJ|rcsb pdb:6NVG|rcsb pdb:6NVH|rcsb pdb:6NVI|rcsb pdb:6NVJ|rcsb pdb:6NVK|rcsb pdb:6V9C|rcsb pdb:6YI8|rcsb pdb:7DTZ|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1307965|reactome:R-HSA-1839128|reactome:R-HSA-190322|reactome:R-HSA-2219530|reactome:R-HSA-5654228|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654733|reactome:R-HSA-5655291|reactome:R-HSA-5673001|reactome:R-HSA-6811558|rcsb pdb:4TYJ|refseq:NP_002002.3|refseq:NP_075252.2|refseq:NP_998812.1|refseq:XP_005265895.1|dip:DIP-5149N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:JQ3gV5Xg75wwE2tOvcKZ3Vr9Lgg9606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:P51659 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599650|imex:IM-26093-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 rigid:a3fyv7zx/GnCdzN6ySh4y4gWXV8 false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O94966 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2511895|ensembl:ENSP00000381863|uniprotkb:Q641Q9|uniprotkb:Q86XV9|uniprotkb:Q3KQW4|uniprotkb:A6H8U2|uniprotkb:Q6NZY8|uniprotkb:A5PKX8|uniprotkb:B4DGT3|uniprotkb:E7ETS0|uniprotkb:E9PEG8|uniprotkb:B4DTZ0|uniprotkb:E7EN22 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ubp19_human(display_long)|uniprotkb:USP19(gene name)|psi-mi:USP19(display_short)|uniprotkb:KIAA0891(gene name synonym)|uniprotkb:ZMYND9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 19(gene name synonym)|uniprotkb:Deubiquitinating enzyme 19(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 9(gene name synonym)|uniprotkb:Ubiquitin thioesterase 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599663|imex:IM-26093-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000172046(gene)|ensembl:ENST00000398888(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904292"(regulation of ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O94966|rcsb pdb:1WH0|rcsb pdb:4X3G|rcsb pdb:6K7W|rcsb pdb:6KHV|rcsb pdb:6KQV|reactome:R-HSA-5689880|refseq:NP_001186089.1|refseq:NP_001186090.1|refseq:NP_001186091.1|refseq:NP_006668.1|refseq:XP_005264888.1|refseq:XP_016861115.1|refseq:XP_016861122.1 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:5U3FuLQ44MsWtu7o/3bY7seGC3M9606 rigid:z2RdTftuOtt1Gn4Wpo5EFvpzVB8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O00499 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599663|imex:IM-26093-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:z2RdTftuOtt1Gn4Wpo5EFvpzVB8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q04837 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599663|imex:IM-26093-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:z2RdTftuOtt1Gn4Wpo5EFvpzVB8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q8NBS9 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599663|imex:IM-26093-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:z2RdTftuOtt1Gn4Wpo5EFvpzVB8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q7RTV0 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599663|imex:IM-26093-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rigid:z2RdTftuOtt1Gn4Wpo5EFvpzVB8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:P22455 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-6256193|uniprotkb:G3JVM2|uniprotkb:G3JVM5|uniprotkb:G3JVM7|uniprotkb:G3JVM9|uniprotkb:Q96KE5|ensembl:ENSP00000292408|ensembl:ENSP00000424960|uniprotkb:O43785|uniprotkb:Q14309|uniprotkb:Q71TW8|uniprotkb:Q8TDA0 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:fgfr4_human(display_long)|uniprotkb:FGFR4(gene name)|psi-mi:FGFR4(display_short)|uniprotkb:JTK2(gene name synonym)|uniprotkb:TKF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599663|imex:IM-26093-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001278909.1|ensembl:ENSG00000160867(gene)|ensembl:ENST00000292408(transcript)|ensembl:ENST00000502906(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030133"(transport vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055062"(phosphate ion homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR016248(Fibroblast growth factor receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|mint:P22455|rcsb pdb:1QCT|rcsb pdb:4QQ5|rcsb pdb:4QQC|rcsb pdb:4QQJ|rcsb pdb:4QQT|rcsb pdb:4QRC|rcsb pdb:4R6V|rcsb pdb:4TYE|rcsb pdb:4TYG|rcsb pdb:4TYI|rcsb pdb:4UXQ|rcsb pdb:4XCU|rcsb pdb:5JKG|rcsb pdb:5NUD|rcsb pdb:5NWZ|rcsb pdb:5XFF|rcsb pdb:5XFJ|rcsb pdb:6IUO|rcsb pdb:6IUP|rcsb pdb:6J6Y|rcsb pdb:6JPE|rcsb pdb:6JPJ|rcsb pdb:6NVG|rcsb pdb:6NVH|rcsb pdb:6NVI|rcsb pdb:6NVJ|rcsb pdb:6NVK|rcsb pdb:6V9C|rcsb pdb:6YI8|rcsb pdb:7DTZ|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1307965|reactome:R-HSA-1839128|reactome:R-HSA-190322|reactome:R-HSA-2219530|reactome:R-HSA-5654228|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654733|reactome:R-HSA-5655291|reactome:R-HSA-5673001|reactome:R-HSA-6811558|rcsb pdb:4TYJ|refseq:NP_002002.3|refseq:NP_075252.2|refseq:NP_998812.1|refseq:XP_005265895.1|dip:DIP-5149N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:JQ3gV5Xg75wwE2tOvcKZ3Vr9Lgg9606 rigid:z2RdTftuOtt1Gn4Wpo5EFvpzVB8 false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O94966 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2511895|ensembl:ENSP00000381863|uniprotkb:Q641Q9|uniprotkb:Q86XV9|uniprotkb:Q3KQW4|uniprotkb:A6H8U2|uniprotkb:Q6NZY8|uniprotkb:A5PKX8|uniprotkb:B4DGT3|uniprotkb:E7ETS0|uniprotkb:E9PEG8|uniprotkb:B4DTZ0|uniprotkb:E7EN22 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ubp19_human(display_long)|uniprotkb:USP19(gene name)|psi-mi:USP19(display_short)|uniprotkb:KIAA0891(gene name synonym)|uniprotkb:ZMYND9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 19(gene name synonym)|uniprotkb:Deubiquitinating enzyme 19(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 9(gene name synonym)|uniprotkb:Ubiquitin thioesterase 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599676|imex:IM-26093-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000172046(gene)|ensembl:ENST00000398888(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904292"(regulation of ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O94966|rcsb pdb:1WH0|rcsb pdb:4X3G|rcsb pdb:6K7W|rcsb pdb:6KHV|rcsb pdb:6KQV|reactome:R-HSA-5689880|refseq:NP_001186089.1|refseq:NP_001186090.1|refseq:NP_001186091.1|refseq:NP_006668.1|refseq:XP_005264888.1|refseq:XP_016861115.1|refseq:XP_016861122.1 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:5U3FuLQ44MsWtu7o/3bY7seGC3M9606 rigid:fE6T9BtwdQ2rMa/yP1N4vsSw9PQ false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O00499 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599676|imex:IM-26093-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:fE6T9BtwdQ2rMa/yP1N4vsSw9PQ false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q8NBS9 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599676|imex:IM-26093-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:fE6T9BtwdQ2rMa/yP1N4vsSw9PQ false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O94966 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2511895|ensembl:ENSP00000381863|uniprotkb:Q641Q9|uniprotkb:Q86XV9|uniprotkb:Q3KQW4|uniprotkb:A6H8U2|uniprotkb:Q6NZY8|uniprotkb:A5PKX8|uniprotkb:B4DGT3|uniprotkb:E7ETS0|uniprotkb:E9PEG8|uniprotkb:B4DTZ0|uniprotkb:E7EN22 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ubp19_human(display_long)|uniprotkb:USP19(gene name)|psi-mi:USP19(display_short)|uniprotkb:KIAA0891(gene name synonym)|uniprotkb:ZMYND9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 19(gene name synonym)|uniprotkb:Deubiquitinating enzyme 19(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 9(gene name synonym)|uniprotkb:Ubiquitin thioesterase 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599687|imex:IM-26093-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000172046(gene)|ensembl:ENST00000398888(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904292"(regulation of ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O94966|rcsb pdb:1WH0|rcsb pdb:4X3G|rcsb pdb:6K7W|rcsb pdb:6KHV|rcsb pdb:6KQV|reactome:R-HSA-5689880|refseq:NP_001186089.1|refseq:NP_001186090.1|refseq:NP_001186091.1|refseq:NP_006668.1|refseq:XP_005264888.1|refseq:XP_016861115.1|refseq:XP_016861122.1 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:5U3FuLQ44MsWtu7o/3bY7seGC3M9606 rigid:fE6T9BtwdQ2rMa/yP1N4vsSw9PQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O00499 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599687|imex:IM-26093-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:fE6T9BtwdQ2rMa/yP1N4vsSw9PQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q8NBS9 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599687|imex:IM-26093-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:fE6T9BtwdQ2rMa/yP1N4vsSw9PQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:P22087 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:Q32P51 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-2556580|uniprotkb:Q5TBS2|ensembl:ENSP00000350090 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:ra1l2_human(display_long)|uniprotkb:HNRNPA1L(gene name synonym)|uniprotkb:HNRNPA1L2(gene name)|psi-mi:HNRNPA1L2(display_short)|uniprotkb:hnRNP core protein A1-like 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001011724.1|refseq:NP_001011725.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0051028"(mRNA transport)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR035979|mint:Q32P51|go:"GO:0005681"(spliceosomal complex)|ensembl:ENSG00000139675(gene)|ensembl:ENST00000357495(transcript)|go:"GO:0003723"(RNA binding) - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:Xx00SLimJrf+0e9CrvzUV9PJPcI9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:P56182 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:P51575 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-11599725|uniprotkb:Q9UK84|ensembl:ENSP00000225538 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:p2rx1_human(display_long)|uniprotkb:ATP receptor(gene name synonym)|uniprotkb:Purinergic receptor(gene name synonym)|uniprotkb:P2RX1(gene name)|psi-mi:P2RX1(display_short)|uniprotkb:P2X1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_002549.1|ensembl:ENSG00000108405(gene)|ensembl:ENST00000225538(transcript)|go:"GO:0001614"(purinergic nucleotide receptor activity)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004931"(extracellularly ATP-gated cation channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007320"(insemination)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030168"(platelet activation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099509"(regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001429(P2X purinoreceptor)|interpro:IPR003044(P2X1 purinoceptor)|interpro:IPR027309|reactome:R-HSA-139853|reactome:R-HSA-418346|reactome:R-HSA-6798695|go:"GO:0042802"(identical protein binding) - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:l7rirQdU03+GvAK7rHtI4YjveDE9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:Q9NY93 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-372376|uniprotkb:Q9H9I8|intact:EBI-1051948|uniprotkb:Q6IAE2|uniprotkb:A4D2K9|ensembl:ENSP00000258772|uniprotkb:C9JV95 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:ddx56_human(display_long)|uniprotkb:DDX56(gene name)|psi-mi:DDX56(display_short)|uniprotkb:DDX21(gene name synonym)|uniprotkb:DEAD box protein 56(gene name synonym)|uniprotkb:ATP-dependent 61 kDa nucleolar RNA helicase(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:NOH61(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_061955.1|ensembl:ENSG00000136271(gene)|ensembl:ENST00000258772(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NY93|refseq:NP_001244118.1 - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:Pfa1hEJ7HnBZtSO4aZ2xRixpldc9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:Q5T9A4 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:O14617 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003929.4|refseq:NP_001248755.1|ensembl:ENSG00000065000(gene)|ensembl:ENST00000345016(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|dip:DIP-46793N - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045603 uniprotkb:Q8NET6 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 intact:EBI-11599701|uniprotkb:Q3SYA3|uniprotkb:Q3SYA5|ensembl:ENSP00000317404 psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:chstd_human(display_long)|uniprotkb:CHST13(gene name)|psi-mi:CHST13(display_short)|uniprotkb:Chondroitin 4-O-sulfotransferase 3(gene name synonym)|uniprotkb:Chondroitin 4-sulfotransferase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599695|imex:IM-26093-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_690849.1|ensembl:ENSG00000180767(gene)|ensembl:ENST00000319340(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001537"(N-acetylgalactosamine 4-O-sulfotransferase activity)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016051"(carbohydrate biosynthetic process)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|interpro:IPR018011|reactome:R-HSA-2022870|go:"GO:0047756"(chondroitin 4-sulfotransferase activity) - chain-seq-start:2443|chain-seq-end:3033 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rogid:38l+A2GuAQ10zFqaxmsH6+D6V6k9606 rigid:LgQGBPlZ6C/gyvzLyFQkqMpKH/Q false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:O43264 intact:EBI-8772829 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q9Y3D8 intact:EBI-8772829 intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q6NXE6 intact:EBI-8772829 intact:EBI-1053802|uniprotkb:O94999|uniprotkb:Q9BTH5|uniprotkb:B4DI98|ensembl:ENSP00000376148|ensembl:ENSP00000444156 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:armc6_human(display_long)|uniprotkb:ARMC6(gene name)|psi-mi:ARMC6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001186125.1|refseq:NP_219483.1|refseq:XP_005260214.1|ensembl:ENSG00000105676(gene)|ensembl:ENST00000392336(transcript)|ensembl:ENST00000535612(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005829"(cytosol)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040104|refseq:XP_016882974.1 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:GmBkkkIiwWSjy2KIay/KQ8VTZgk9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q9H840 intact:EBI-8772829 intact:EBI-715455|uniprotkb:Q6IA34|ensembl:ENSP00000375813|ensembl:ENSP00000465704|ensembl:ENSP00000466342|ensembl:ENSP00000270257 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:gemi7_human(display_long)|uniprotkb:SIP3(gene name synonym)|uniprotkb:GEMIN7(gene name)|psi-mi:GEMIN7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:XP_005259319.1|refseq:XP_005259320.1|refseq:NP_001007270.1|refseq:NP_001007271.1|refseq:NP_078983.1|ensembl:ENSG00000142252(gene)|ensembl:ENST00000270257(transcript)|ensembl:ENST00000391951(transcript)|ensembl:ENST00000591607(transcript)|ensembl:ENST00000591747(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0120114"(Sm-like protein family complex)|interpro:IPR020338|interpro:IPR024642|mint:Q9H840|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|refseq:NP_001305983.1|refseq:NP_001305984.1|refseq:XP_016882801.1|dip:DIP-41750N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:jnNKbzuQxiIWKDmv7+je9B5U81Q9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:O60220 intact:EBI-8772829 intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q58FF3 intact:EBI-8772829 intact:EBI-11599825 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:enpll_human(display_long)|uniprotkb:HSP90B2P(gene name)|psi-mi:HSP90B2P(display_short)|uniprotkb:GRP94B(gene name synonym)|uniprotkb:GRP94P1(gene name synonym)|uniprotkb:TRAP1(gene name synonym)|uniprotkb:Putative heat shock protein 90 kDa beta member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020568|interpro:IPR037196|go:"GO:0005524"(ATP binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding) - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:kF+lTELesh6FWnEw+Mrf78OPpL09606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q8WTW3 intact:EBI-8772829 intact:EBI-368371|uniprotkb:Q9P2G6|uniprotkb:Q9NPV9|ensembl:ENSP00000299886 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:cog1_human(display_long)|uniprotkb:COG1(gene name)|psi-mi:COG1(display_short)|uniprotkb:KIAA1381(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 1(gene name synonym)|uniprotkb:LDLB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_061184.1|ensembl:ENSG00000166685(gene)|ensembl:ENST00000299886(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|interpro:IPR033370|mint:Q8WTW3|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|go:"GO:0015031"(protein transport) - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:zUXskbnET4Wp0wRsjxwtE33ccCA9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q96P70 intact:EBI-8772829 intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q9NR31 intact:EBI-8772829 intact:EBI-3920694|uniprotkb:B4DQ19|ensembl:ENSP00000362335|ensembl:ENSP00000362338|ensembl:ENSP00000362339|ensembl:ENSP00000399698 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:sar1a_human(display_long)|uniprotkb:SAR1A(gene name)|psi-mi:SAR1A(display_short)|uniprotkb:SAR1(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SARA1(gene name synonym)|uniprotkb:COPII-associated small GTPase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000079332(gene)|ensembl:ENST00000373238(transcript)|ensembl:ENST00000373241(transcript)|ensembl:ENST00000373242(transcript)|ensembl:ENST00000431664(transcript)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0061024"(membrane organization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006687(GTP-binding protein SAR1)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:Q9NR31|rcsb pdb:2GAO|refseq:NP_001136120.1|refseq:NP_064535.1|dip:DIP-59790N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:Wgq8eFE+YfSt/fs1cpGicDT0rMA9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:O94813 intact:EBI-8772829 intact:EBI-1236865|uniprotkb:O95710|uniprotkb:Q17RU3|uniprotkb:Q9Y5Q7|uniprotkb:B7ZLR5|uniprotkb:A0A0A6YYB8|ensembl:ENSP00000422591 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:slit2_human(display_long)|uniprotkb:SLIT2(gene name)|psi-mi:SLIT2(display_short)|uniprotkb:SLIL3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001276064.1|refseq:NP_001276065.1|refseq:NP_004778.1|dip:DIP-38198N|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021972"(corticospinal neuron axon guidance through spinal cord)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071676"(negative regulation of mononuclear cell migration)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:O94813|rcsb pdb:2V70|rcsb pdb:2V9S|rcsb pdb:2V9T|rcsb pdb:2WFH|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-9010553|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|ensembl:ENSG00000145147(gene)|ensembl:ENST00000504154(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002689"(negative regulation of leukocyte chemotaxis)|go:"GO:0003180"(aortic valve morphogenesis) - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:25Wc98dEfv1yROTD5pUtyQ+LWN89606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q14746 intact:EBI-8772829 intact:EBI-389449|uniprotkb:Q86U99|ensembl:ENSP00000355629 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:cog2_human(display_long)|uniprotkb:COG2(gene name)|psi-mi:COG2(display_short)|uniprotkb:LDLC(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 2(gene name synonym)|uniprotkb:Low density lipoprotein receptor defect C-complementing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_031383.1|refseq:NP_001138508.1|ensembl:ENSG00000135775(gene)|ensembl:ENST00000366669(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR009316(COG complex component, COG2)|interpro:IPR024602|interpro:IPR024603|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:LikqIIuX72shymiuUF977aVlfpE9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q9UPT5 intact:EBI-8772829 intact:EBI-720048|uniprotkb:Q96FF0|uniprotkb:Q9H8C3|uniprotkb:Q9H9X3|uniprotkb:Q9HA32|uniprotkb:Q8ND93|uniprotkb:Q8WV91|uniprotkb:B5MC69|uniprotkb:B8XXP2|ensembl:ENSP00000334100 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:exoc7_human(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001013861.1|refseq:NP_001138769.1|refseq:NP_001138770.1|refseq:NP_001138771.1|refseq:NP_056034.2|ensembl:ENSG00000182473(gene)|ensembl:ENST00000335146(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032584"(growth cone membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|mint:Q9UPT5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_001269242.1|dip:DIP-37604N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:f/uwscxIcAuG96QZzNMQtrzTmeU9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q9NTJ3 intact:EBI-8772829 intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q9H0F6 intact:EBI-8772829 intact:EBI-3942966|uniprotkb:D3DWL3|uniprotkb:Q8IXF5|uniprotkb:Q8IXF6|uniprotkb:A6NEG3|uniprotkb:Q8TB25|uniprotkb:Q9BUE4|uniprotkb:Q8N2E7|uniprotkb:C0L3L2|ensembl:ENSP00000381698 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:shrpn_human(display_long)|uniprotkb:SHARPIN(gene name)|psi-mi:SHARPIN(display_short)|uniprotkb:SIPL1(gene name synonym)|uniprotkb:Shank-associated RH domain-interacting protein(gene name synonym)|uniprotkb:Shank-interacting protein-like 1(gene name synonym)|uniprotkb:PSEC0216(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000179526(gene)|ensembl:ENST00000398712(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007420"(brain development)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0030425"(dendrite)|go:"GO:0031424"(keratinization)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:2000348"(regulation of CD40 signaling pathway)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR026261|reactome:R-HSA-6794361|interpro:IPR029071|interpro:IPR031912|interpro:IPR036443|mint:Q9H0F6|rcsb pdb:4EMO|rcsb pdb:5X0W|reactome:R-HSA-5357905|reactome:R-HSA-5357956|refseq:NP_112236.3|refseq:XP_016869377.1|dip:DIP-57842N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:+RGl3JO1zsGCdaInDn20yhNZs0E9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q96S52 intact:EBI-8772829 intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q96MW5 intact:EBI-8772829 intact:EBI-720875|ensembl:ENSP00000305459|uniprotkb:Q8WVV6|uniprotkb:Q9H6F8|uniprotkb:Q0VAK2 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:cog8_human(display_long)|uniprotkb:Component of oligomeric Golgi complex 8(gene name synonym)|uniprotkb:COG8(gene name)|psi-mi:COG8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000213380(gene)|ensembl:ENST00000306875(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|interpro:IPR007255(Dor1-like protein)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR016632(Conserved oligomeric Golgi complex, COG8)|mint:Q96MW5|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_115758.3 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:X9AZmEQ+B2Jc9kwFXAgxZp6S0sI9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q96JJ7 intact:EBI-8772829 intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q969Z0 intact:EBI-8772829 intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q8NF37 intact:EBI-8772829 intact:EBI-922595|uniprotkb:Q1HAQ1|uniprotkb:Q7Z4G6|uniprotkb:Q8N3U7|uniprotkb:Q8WUL8|uniprotkb:Q9GZW6|ensembl:ENSP00000283415|ensembl:ENSP00000423472 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:pcat1_human(display_long)|uniprotkb:1-alkylglycerophosphocholine O-acetyltransferase(gene name synonym)|uniprotkb:Acyltransferase-like 2(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 3(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase(gene name synonym)|uniprotkb:1-alkenylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:LPCAT1(gene name)|psi-mi:LPCAT1(display_short)|uniprotkb:AYTL2(gene name synonym)|uniprotkb:PFAAP3(gene name synonym)|uniprotkb:"Acetyl-CoA:lyso-platelet-activating factor acetyltransferase"(gene name synonym)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_079106.3|ensembl:ENSG00000153395(gene)|ensembl:ENST00000283415(transcript)|ensembl:ENST00000475622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0047159"(1-alkenylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047191"(1-alkylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047192"(1-alkylglycerophosphocholine O-acetyltransferase activity)|go:"GO:0050200"(plasmalogen synthase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR011992(EF-Hand type)|reactome:R-HSA-1482788|reactome:R-HSA-1482925|reactome:R-HSA-1483166|reactome:R-HSA-1483191|reactome:R-HSA-6798695 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:sJPdIAauFmV71N/KwIUH75hTHv09606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q86TG7 intact:EBI-8772829 intact:EBI-2858265|uniprotkb:Q9UPV1|uniprotkb:Q96A68 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:peg10_human(display_long)|uniprotkb:PEG10(gene name)|psi-mi:PEG10(display_short)|uniprotkb:EDR(gene name synonym)|uniprotkb:KIAA1051(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:MART2(gene name synonym)|uniprotkb:MEF3L1(gene name synonym)|uniprotkb:RGAG3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation-regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) interpro:IPR032549|interpro:IPR032567|refseq:NP_001035242.1|refseq:NP_001171890.1|refseq:NP_001171891.1|refseq:NP_055883.2|interpro:IPR021109|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|interpro:IPR043128|interpro:IPR043502 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:wkCBsH9/PsFMwJFu/qOwZcn63D49606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q6NUK1 intact:EBI-8772829 intact:EBI-4289949|uniprotkb:Q705K4|uniprotkb:B7ZAI9|uniprotkb:Q5T331|uniprotkb:Q9P129|uniprotkb:Q5T485|uniprotkb:Q6PJJ9|ensembl:ENSP00000457733|ensembl:ENSP00000491572 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:scmc1_human(display_long)|uniprotkb:SLC25A24(gene name)|psi-mi:SLC25A24(display_short)|uniprotkb:APC1(gene name synonym)|uniprotkb:MCSC1(gene name synonym)|uniprotkb:SCAMC1(gene name synonym)|uniprotkb:Mitochondrial ATP-Mg/Pi carrier protein 1(gene name synonym)|uniprotkb:"Mitochondrial Ca(2+)-dependent solute carrier protein 1"(gene name synonym)|uniprotkb:Small calcium-binding mitochondrial carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_037518.3|refseq:NP_998816.1|ensembl:ENSG00000085491(gene)|ensembl:ENSG00000284468(gene)|ensembl:ENST00000565488(transcript)|ensembl:ENST00000640416(transcript)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0010941"(regulation of cell death)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q6NUK1|rcsb pdb:4N5X|rcsb pdb:4ZCU|rcsb pdb:4ZCV - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:2zVynZiDVY5UzziL6TAmqK/fkB09606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:P28066 intact:EBI-8772829 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045597 uniprotkb:Q96JB2 intact:EBI-8772829 intact:EBI-2807756|ensembl:ENSP00000258654|uniprotkb:Q5VT70|uniprotkb:B2RAW5|uniprotkb:Q9BZ92|uniprotkb:Q8IXX4 psi-mi:q99ib8-pro_0000045597(display_long) psi-mi:cog3_human(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Vesicle-docking protein SEC34 homolog(gene name synonym)|uniprotkb:p94(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11599782|imex:IM-26093-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000136152(gene)|ensembl:ENST00000349995(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR007265(Sec34-like protein)|mint:Q96JB2|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_113619.2 - chain-seq-start:751|chain-seq-end:813 - figure legend:table S3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/02/18 rogid:g1N1nFD9PcDZYobytpfV14YG0no356411 rogid:P3sc7TLrhgqNPIh7VYpmsoIhSrE9606 rigid:EFQ01auQVghfexxKQo3prBeUKIY false flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q7RTV0 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422306|imex:IM-26093-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) - chain-seq-start:1977|chain-seq-end:2442 - figure legend:S1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2015/11/23 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rigid:X9lvfrGwVBGFLbMs+vX4nkqO4y8 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q8NBS9 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422306|imex:IM-26093-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:S1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2015/11/23 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:X9lvfrGwVBGFLbMs+vX4nkqO4y8 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:Q04837 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422306|imex:IM-26093-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:S1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2015/11/23 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:X9lvfrGwVBGFLbMs+vX4nkqO4y8 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O94966 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-2511895|ensembl:ENSP00000381863|uniprotkb:Q641Q9|uniprotkb:Q86XV9|uniprotkb:Q3KQW4|uniprotkb:A6H8U2|uniprotkb:Q6NZY8|uniprotkb:A5PKX8|uniprotkb:B4DGT3|uniprotkb:E7ETS0|uniprotkb:E9PEG8|uniprotkb:B4DTZ0|uniprotkb:E7EN22 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:ubp19_human(display_long)|uniprotkb:USP19(gene name)|psi-mi:USP19(display_short)|uniprotkb:KIAA0891(gene name synonym)|uniprotkb:ZMYND9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 19(gene name synonym)|uniprotkb:Deubiquitinating enzyme 19(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 9(gene name synonym)|uniprotkb:Ubiquitin thioesterase 19(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422306|imex:IM-26093-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000172046(gene)|ensembl:ENST00000398888(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904292"(regulation of ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O94966|rcsb pdb:1WH0|rcsb pdb:4X3G|rcsb pdb:6K7W|rcsb pdb:6KHV|rcsb pdb:6KQV|reactome:R-HSA-5689880|refseq:NP_001186089.1|refseq:NP_001186090.1|refseq:NP_001186091.1|refseq:NP_006668.1|refseq:XP_005264888.1|refseq:XP_016861115.1|refseq:XP_016861122.1 - chain-seq-start:1977|chain-seq-end:2442 - figure legend:S1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2015/11/23 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:5U3FuLQ44MsWtu7o/3bY7seGC3M9606 rigid:X9lvfrGwVBGFLbMs+vX4nkqO4y8 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045602 uniprotkb:O00499 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11422306|imex:IM-26093-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - chain-seq-start:1977|chain-seq-end:2442 - figure legend:S1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2015/11/23 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:X9lvfrGwVBGFLbMs+vX4nkqO4y8 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P0L0 uniprotkb:Q99IB8-PRO_0000045600 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-9096996 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425148|imex:IM-26093-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) intact:EBI-6674379(chain-parent) - - chain-seq-start:1662|chain-seq-end:1715 figure legend:S5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2016/04/19 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rigid:L7q8/b4UmC0pMchouFP2k2YyBrs false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P0L0 uniprotkb:Q99IB8-PRO_0000045603 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425148|imex:IM-26093-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) intact:EBI-6674379(chain-parent) - - chain-seq-start:2443|chain-seq-end:3033 figure legend:S5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2016/04/19 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rigid:L7q8/b4UmC0pMchouFP2k2YyBrs false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P0L0 uniprotkb:Q99IB8-PRO_0000045599 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-6858501|intact:EBI-6927943 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425148|imex:IM-26093-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) intact:EBI-6674379(chain-parent) - - chain-seq-start:1031|chain-seq-end:1661 figure legend:S5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2016/04/19 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rigid:L7q8/b4UmC0pMchouFP2k2YyBrs false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99IB8-PRO_0000045601 uniprotkb:O43169 intact:EBI-6928570|intact:EBI-8786387 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:q99ib8-pro_0000045601(display_long) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425133|imex:IM-26093-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - chain-seq-start:1716|chain-seq-end:1976 - figure legend:4C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2019/05/28 rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:+nose7rUkZfjUkoYH0aH9mZNyZ0 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BRP8 uniprotkb:Q9Y5S9 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687762|imex:IM-26093-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 - - - figure legend:S6D|antagonist:"q99ib8-pro_0000045592 -Flag-Core (2a)"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BRP8 uniprotkb:P61326 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687762|imex:IM-26093-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N - - - figure legend:S6D|antagonist:"q99ib8-pro_0000045592 -Flag-Core (2a)"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P0L0 uniprotkb:Q99IB8-PRO_0000045600 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-9096996 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425155|imex:IM-26093-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) intact:EBI-6674379(chain-parent) - - chain-seq-start:1662|chain-seq-end:1715 figure legend:5B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rigid:LqUSO60VdMHleKb66n4PawAjJEs false v5 tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q99IB8-PRO_0000045600 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-9096996 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425164|imex:IM-26093-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) intact:EBI-6674379(chain-parent) - chain-seq-start:1031|chain-seq-end:1661 chain-seq-start:1662|chain-seq-end:1715 figure legend:5B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rigid:eBsAjO0KLvWQF7pAH/0B6wX9XA0 false flag tag:?-? strep tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q9P0L0 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425164|imex:IM-26093-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - chain-seq-start:1031|chain-seq-end:1661 - figure legend:5B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:eBsAjO0KLvWQF7pAH/0B6wX9XA0 false flag tag:?-? v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95292 uniprotkb:Q99IB8-PRO_0000045600 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 intact:EBI-9096996 psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425175|imex:IM-26093-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N intact:EBI-6674379(chain-parent) - - chain-seq-start:1662|chain-seq-end:1715 figure legend:5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rigid:jD8OEIp6q3Kd55n0DpNm85Sdk7c false v5 tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:Q99IB8-PRO_0000045600 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-9096996 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:q99ib8-pro_0000045600(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425183|imex:IM-26093-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) intact:EBI-6674379(chain-parent) - chain-seq-start:1031|chain-seq-end:1661 chain-seq-start:1662|chain-seq-end:1715 figure legend:5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:53wXvgKEjvo0j6aocWrpMcJrcIs356411 rigid:OBQESb1h5UR7vTiO5Ebg4kjjj38 false flag tag:?-? strep tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99IB8-PRO_0000045599 uniprotkb:O95292 intact:EBI-6858501|intact:EBI-6927943 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:q99ib8-pro_0000045599(display_long) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425183|imex:IM-26093-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - chain-seq-start:1031|chain-seq-end:1661 - figure legend:5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:OBQESb1h5UR7vTiO5Ebg4kjjj38 false flag tag:?-? v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95292 uniprotkb:Q99IB8-PRO_0000045602 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425194|imex:IM-26093-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N intact:EBI-6674379(chain-parent) - - chain-seq-start:1977|chain-seq-end:2442 figure legend:5C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rigid:6QZzr1SX3XFGCZ7EAvHi/hR3q/k false v5 tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95292 uniprotkb:Q99IB8-PRO_0000045603 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11425202|imex:IM-26093-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N intact:EBI-6674379(chain-parent) - - chain-seq-start:2443|chain-seq-end:3033 figure legend:S5A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2015/11/25 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 rigid:hUYkUJkkuatybAJA0AyTFNXRDcw false v5 tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99IB8-PRO_0000045592 uniprotkb:Q9BRP8 intact:EBI-6858513|intact:EBI-6929338 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11428138|imex:IM-26093-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6674379(chain-parent) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 - chain-seq-start:2|chain-seq-end:191 - figure legend:S6B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/04/25 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rigid:yACfjgAs2iY8lg8/+rpF9pm4f24 false flag tag:n-n ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P0L0 uniprotkb:Q99IB8-PRO_0000045602 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:q99ib8-pro_0000045602(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687754|imex:IM-26093-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) intact:EBI-6674379(chain-parent) - - chain-seq-start:1977|chain-seq-end:2442 figure legend:5B|comment:weak interaction|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2015/11/19 2016/04/19 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411 rigid:mstcZFuraaEgkai0XEXl8gXu+2w false v5 tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:Q99IB8-PRO_0000045592 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-6858513|intact:EBI-6929338 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11428121|imex:IM-26093-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 intact:EBI-6674379(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:6B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rigid:yACfjgAs2iY8lg8/+rpF9pm4f24 false ha tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:Q68842 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-11687770 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:q68842_9hepc(display_long)|uniprotkb:HCV core(gene name)|psi-mi:HCV core(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:31647(hepatitis c virus subtype 1b)|taxid:31647(Hepatitis C virus subtype 1b) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687779|imex:IM-26093-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:S6A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/19 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:Gnh8OZNXmn0NlYoXgYbPVwDesRs31647 rigid:soRx4gwwJFx6On9uA/r0kbNa5dk false v5 tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:Q9Y5S9 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687787|imex:IM-26093-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 - - - figure legend:S6C|antagonist:Q68842 - Core protein Genotype 1B.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:P61326 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687787|imex:IM-26093-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N - - - figure legend:S6C|antagonist:Q68842 - Core protein Genotype 1B.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:Q68842 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-11687770 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:q68842_9hepc(display_long)|uniprotkb:HCV core(gene name)|psi-mi:HCV core(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:31647(hepatitis c virus subtype 1b)|taxid:31647(Hepatitis C virus subtype 1b) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687797|imex:IM-26093-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:6D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/19 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:Gnh8OZNXmn0NlYoXgYbPVwDesRs31647 rigid:soRx4gwwJFx6On9uA/r0kbNa5dk false ha tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:P06935-PRO_0000037743 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-11687805 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:p06935-pro_0000037743(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11082(wnv)|taxid:11082("West Nile virus (WNV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687809|imex:IM-26093-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 intact:EBI-981051(chain-parent) - - chain-seq-start:1|chain-seq-end:105 figure legend:6C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2017/10/20 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:Di7nsLcPb8625WMB5O4+MOBziYQ11082 rigid:F3eQA3FcWgjN+7Z3s7w5o3UU9r4 false ha tag:c-c strep tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:P17763-PRO_0000264658 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-11687890 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:p17763-pro_0000264658(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11059(DENV-1)|taxid:11059("Dengue virus type 1 (strain Nauru/West Pac/1974)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11687894|imex:IM-26093-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 intact:EBI-11687818(chain-parent) - - chain-seq-start:1|chain-seq-end:100 figure legend:6C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/19 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:+8Pkkb/7u4Bm3pdwM9SgKH1tDVE11059 rigid:xHS2RFyky43/m1gKHeSDGjLWwlM false ha tag:c-c strep tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BRP8 uniprotkb:P61326 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11428146|imex:IM-26093-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N - - - figure legend:6E|comment:"When cells are HCV infected interaction with MAGOH is decreased. Cells were infected with a chimeric virus - Jc1 (1-846(J6CF)/847-3034(JFH1), both 2a genotype. (PMID:16651538)"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rigid:0ZyYwrADzi445ibNDUuo37KfVrw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BRP8 uniprotkb:Q99IB8-PRO_0000045592 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-6858513|intact:EBI-6929338 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:q99ib8-pro_0000045592(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11428146|imex:IM-26093-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 intact:EBI-6674379(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:6E|comment:"When cells are HCV infected interaction with MAGOH is decreased. Cells were infected with a chimeric virus - Jc1 (1-846(J6CF)/847-3034(JFH1), both 2a genotype. (PMID:16651538)"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411 rigid:0ZyYwrADzi445ibNDUuo37KfVrw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61326 uniprotkb:Q9BRP8 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11689792|imex:IM-26093-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 - - - figure legend:6Ei|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2015/11/19 2016/04/25 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rigid:JRbZEWToT68vTyMtERq+CvL2cV0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BRP8 uniprotkb:Q9Y5S9 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11690546|imex:IM-26093-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 - - - figure legend:6Di|antagonist:"q99ib8-pro_0000045592 -Flag-Core (2a)"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BRP8 uniprotkb:P61326 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ramage et al. (2015) pubmed:25616068|imex:IM-26093 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11690546|imex:IM-26093-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N - - - figure legend:6Di|antagonist:"q99ib8-pro_0000045592 -Flag-Core (2a)"|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/11/19 2016/04/25 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)