#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AEZ3	uniprotkb:P18196	intact:EBI-554545|uniprotkb:P18197|ensemblbacteria:AAC74259|ensemblbacteria:BAA36009	intact:EBI-554060|ensemblbacteria:AAC74260|ensemblbacteria:BAA36010	psi-mi:mind_ecoli(display_long)|uniprotkb:Cell division inhibitor MinD(gene name synonym)|uniprotkb:minD(gene name)|psi-mi:minD(display_short)|uniprotkb:b1175(locus name)|uniprotkb:JW1164(locus name)	psi-mi:minc_ecoli(display_long)|uniprotkb:minC(gene name)|psi-mi:minC(display_short)|uniprotkb:b1176(locus name)|uniprotkb:JW1165(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Conti et al. (2015)	pubmed:25497011|imex:IM-23832	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-10170279|imex:IM-23832-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415693.1|refseq:WP_000101055.1|dip:DIP-35946N|ensemblbacteria:AAC74259(transcript)|ensemblbacteria:b1175(gene)|ensemblbacteria:BAA36009(gene)|ensemblbacteria:BAA36009(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR002586(Cobyrinic acid a,c-diamide synthase)|interpro:IPR010223(Septum site-determining protein MinD)|interpro:IPR025501|interpro:IPR027417|rcsb pdb:3Q9L|rcsb pdb:3R9I|rcsb pdb:3R9J	refseq:NP_415694.1|refseq:WP_001301105.1|dip:DIP-10214N|ensemblbacteria:AAC74260(transcript)|ensemblbacteria:b1176(gene)|ensemblbacteria:BAA36010(gene)|ensemblbacteria:BAA36010(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000917"(division septum assembly)|go:"GO:0005829"(cytosol)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR005526(Septum formation inhibitor MinC, C-terminal)|interpro:IPR007874(Septum formation inhibitor MinC, N-terminal)|interpro:IPR013033(Septum formation inhibitor MinC)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036145	-	-	-	figure legend:f2b f2c f2d f5|comment:MinE disassembles ATP-dependent MinCD polymers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/12	2015/02/13	rogid:M2AqV+JcsIyIROVEjr4ehQ9LNEw83333	rogid:I3pH9r9zoquWuUtf48oxBzCyeyc83333	intact-crc:D49EF20C9B9978AE|rigid:tESyr5Gf35vmr1f7nOKet286C7s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AEZ3	uniprotkb:P18196	intact:EBI-554545|uniprotkb:P18197|ensemblbacteria:AAC74259|ensemblbacteria:BAA36009	intact:EBI-554060|ensemblbacteria:AAC74260|ensemblbacteria:BAA36010	psi-mi:mind_ecoli(display_long)|uniprotkb:Cell division inhibitor MinD(gene name synonym)|uniprotkb:minD(gene name)|psi-mi:minD(display_short)|uniprotkb:b1175(locus name)|uniprotkb:JW1164(locus name)	psi-mi:minc_ecoli(display_long)|uniprotkb:minC(gene name)|psi-mi:minC(display_short)|uniprotkb:b1176(locus name)|uniprotkb:JW1165(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Conti et al. (2015)	pubmed:25497011|imex:IM-23832	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-10170264|imex:IM-23832-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415693.1|refseq:WP_000101055.1|dip:DIP-35946N|ensemblbacteria:AAC74259(transcript)|ensemblbacteria:b1175(gene)|ensemblbacteria:BAA36009(gene)|ensemblbacteria:BAA36009(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR002586(Cobyrinic acid a,c-diamide synthase)|interpro:IPR010223(Septum site-determining protein MinD)|interpro:IPR025501|interpro:IPR027417|rcsb pdb:3Q9L|rcsb pdb:3R9I|rcsb pdb:3R9J	refseq:NP_415694.1|refseq:WP_001301105.1|dip:DIP-10214N|ensemblbacteria:AAC74260(transcript)|ensemblbacteria:b1176(gene)|ensemblbacteria:BAA36010(gene)|ensemblbacteria:BAA36010(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000917"(division septum assembly)|go:"GO:0005829"(cytosol)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR005526(Septum formation inhibitor MinC, C-terminal)|interpro:IPR007874(Septum formation inhibitor MinC, N-terminal)|interpro:IPR013033(Septum formation inhibitor MinC)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036145	-	-	-	figure legend:f1a f2a sf1a sf1d|comment:"MinC and MinD were incubated in the presence  and absence of ATP, and then reactions were fractionated by ultracentrifugation.  We observed that without ATP, both MinD and  MinC, alone or together, were soluble and predominantly localized  to the supernatant (Fig. 1A). However, when MinC and MinD were  incubated together with ATP, the distribution of both proteins  shifted to the pellet even though only MinD contains a nucleotide-  binding site (46% of MinD fractionated with the pellet). The  ratio of MinD to MinC was calculated to be 1.6:1 (Fig. S1A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/12	2015/02/13	rogid:M2AqV+JcsIyIROVEjr4ehQ9LNEw83333	rogid:I3pH9r9zoquWuUtf48oxBzCyeyc83333	intact-crc:AB1B96B257DA7C1F|rigid:tESyr5Gf35vmr1f7nOKet286C7s	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P18196	uniprotkb:P0AEZ3	intact:EBI-554060|ensemblbacteria:AAC74260|ensemblbacteria:BAA36010	intact:EBI-554545|uniprotkb:P18197|ensemblbacteria:AAC74259|ensemblbacteria:BAA36009	psi-mi:minc_ecoli(display_long)|uniprotkb:minC(gene name)|psi-mi:minC(display_short)|uniprotkb:b1176(locus name)|uniprotkb:JW1165(locus name)	psi-mi:mind_ecoli(display_long)|uniprotkb:Cell division inhibitor MinD(gene name synonym)|uniprotkb:minD(gene name)|psi-mi:minD(display_short)|uniprotkb:b1175(locus name)|uniprotkb:JW1164(locus name)	psi-mi:"MI:0067"(light scattering)	Conti et al. (2015)	pubmed:25497011|imex:IM-23832	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-10171141|imex:IM-23832-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415694.1|refseq:WP_001301105.1|dip:DIP-10214N|ensemblbacteria:AAC74260(transcript)|ensemblbacteria:b1176(gene)|ensemblbacteria:BAA36010(gene)|ensemblbacteria:BAA36010(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000917"(division septum assembly)|go:"GO:0005829"(cytosol)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR005526(Septum formation inhibitor MinC, C-terminal)|interpro:IPR007874(Septum formation inhibitor MinC, N-terminal)|interpro:IPR013033(Septum formation inhibitor MinC)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036145	refseq:NP_415693.1|refseq:WP_000101055.1|dip:DIP-35946N|ensemblbacteria:AAC74259(transcript)|ensemblbacteria:b1175(gene)|ensemblbacteria:BAA36009(gene)|ensemblbacteria:BAA36009(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR002586(Cobyrinic acid a,c-diamide synthase)|interpro:IPR010223(Septum site-determining protein MinD)|interpro:IPR025501|interpro:IPR027417|rcsb pdb:3Q9L|rcsb pdb:3R9I|rcsb pdb:3R9J	-	-	-	figure legend:f1b sf1b|comment:MinE disassembles ATP-dependent MinCD polymers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/12	2015/02/13	rogid:I3pH9r9zoquWuUtf48oxBzCyeyc83333	rogid:M2AqV+JcsIyIROVEjr4ehQ9LNEw83333	intact-crc:A1346E4B84A60775|rigid:tESyr5Gf35vmr1f7nOKet286C7s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18196	uniprotkb:P0AEZ3	intact:EBI-554060|ensemblbacteria:AAC74260|ensemblbacteria:BAA36010	intact:EBI-554545|uniprotkb:P18197|ensemblbacteria:AAC74259|ensemblbacteria:BAA36009	psi-mi:minc_ecoli(display_long)|uniprotkb:minC(gene name)|psi-mi:minC(display_short)|uniprotkb:b1176(locus name)|uniprotkb:JW1165(locus name)	psi-mi:mind_ecoli(display_long)|uniprotkb:Cell division inhibitor MinD(gene name synonym)|uniprotkb:minD(gene name)|psi-mi:minD(display_short)|uniprotkb:b1175(locus name)|uniprotkb:JW1164(locus name)	psi-mi:"MI:0040"(electron microscopy)	Conti et al. (2015)	pubmed:25497011|imex:IM-23832	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-10171168|imex:IM-23832-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415694.1|refseq:WP_001301105.1|dip:DIP-10214N|ensemblbacteria:AAC74260(transcript)|ensemblbacteria:b1176(gene)|ensemblbacteria:BAA36010(gene)|ensemblbacteria:BAA36010(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000917"(division septum assembly)|go:"GO:0005829"(cytosol)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR005526(Septum formation inhibitor MinC, C-terminal)|interpro:IPR007874(Septum formation inhibitor MinC, N-terminal)|interpro:IPR013033(Septum formation inhibitor MinC)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036145	refseq:NP_415693.1|refseq:WP_000101055.1|dip:DIP-35946N|ensemblbacteria:AAC74259(transcript)|ensemblbacteria:b1175(gene)|ensemblbacteria:BAA36009(gene)|ensemblbacteria:BAA36009(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060187"(cell pole)|interpro:IPR002586(Cobyrinic acid a,c-diamide synthase)|interpro:IPR010223(Septum site-determining protein MinD)|interpro:IPR025501|interpro:IPR027417|rcsb pdb:3Q9L|rcsb pdb:3R9I|rcsb pdb:3R9J	-	-	-	figure legend:f3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/12	2015/02/13	rogid:I3pH9r9zoquWuUtf48oxBzCyeyc83333	rogid:M2AqV+JcsIyIROVEjr4ehQ9LNEw83333	intact-crc:26FECB94C50A8ECD|rigid:tESyr5Gf35vmr1f7nOKet286C7s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)