#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P80318	uniprotkb:P04591-PRO_0000038598	intact:EBI-772361|ensembl:ENSMUSP00000001452	intact:EBI-10634977	psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym)	psi-mi:p04591-pro_0000038598(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10634976|imex:IM-23841-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	intact:EBI-6163428(chain-parent)	-	-	chain-seq-start:449|chain-seq-end:500|crc64:9117D426B88A73CB	figure legend:Fig 1E, 1F, 3, Supp Fig 1A, 3, Supp. Table 1|comment:Mutations which increase the Kd to >1uM have been taken as mutants which decrease the strength of the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-7(molar)	2015/02/16	2015/07/01	rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090	rogid:maxbPg1zDMQXgRwCIidWTHov6wU11706	intact-crc:C81E617B05042324|rigid:MP9a9dRz3x2L75KMvxWO++Wo3bo	false	sufficient binding region:210-380(IPR027409)|mutation decreasing interaction strength:228-228|mutation decreasing interaction strength:230-230|mutation decreasing interaction strength:231-231|mutation decreasing interaction strength:299-299|mutation decreasing interaction strength:301-301|mutation decreasing interaction strength:302-302|mutation decreasing interaction strength:303-303|his tag:c-c	mutation:3-3|binding-associated region:3-52	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40337	uniprotkb:P12612	intact:EBI-301246|uniprotkb:Q13599|uniprotkb:B2RE45|uniprotkb:Q6PDA9|ensembl:ENSP00000256474	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	psi-mi:vhl_human(display_long)|uniprotkb:VHL(gene name)|psi-mi:VHL(display_short)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Protein G7(gene name synonym)	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635030|imex:IM-23841-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6BVB|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:4W9I|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:4W9J|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:4W9K|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6SIS|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-1234176|reactome:R-HSA-3232142|rcsb pdb:4W9L|reactome:R-HSA-8951664|rcsb pdb:4WQO|reactome:R-HSA-9682706|reactome:R-HSA-9694686|reactome:R-HSA-9706019|reactome:R-HSA-983168|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|ensembl:ENSG00000134086(gene)|ensembl:ENST00000256474(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050821"(protein stabilization)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|mint:P40337|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|refseq:NP_000542.1|refseq:NP_937799.1|dip:DIP-32585N	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612	-	-	crc64:02C625D329359E61	figure legend:Fig. 1E, 1F, Supp. Fig. 1C, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-7(molar)	2015/02/16	2015/07/03	rogid:KaCKDTSj0xPG9YmfFsXIbkRt3A89606	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	intact-crc:D06307F5D5EFB580|rigid:N4SIpYk9o99251qJgOtIRunLS2w	false	sufficient binding region:111-120|mutation:111-111	sufficient binding region:218-379(IPR027409)|mutation decreasing interaction strength:319-319|mutation decreasing interaction strength:326-326|mutation decreasing interaction strength:311-311|mutation decreasing interaction strength:305-305	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04591-PRO_0000038598	uniprotkb:P80318	intact:EBI-10634977	intact:EBI-772361|ensembl:ENSMUSP00000001452	psi-mi:p04591-pro_0000038598(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635171|imex:IM-23841-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6163428(chain-parent)	refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	chain-seq-start:449|chain-seq-end:500|crc64:9117D426B88A73CB	-	figure legend:Fig 2 and Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/16	2015/07/01	rogid:maxbPg1zDMQXgRwCIidWTHov6wU11706	rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090	intact-crc:6BB20D0E8CD24D76|rigid:MP9a9dRz3x2L75KMvxWO++Wo3bo	false	binding-associated region:3-52|mutation:3-3|necessary binding region:43-47	sufficient binding region:210-380(IPR027409)|15n label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04591-PRO_0000038598	uniprotkb:P80318	intact:EBI-10634977	intact:EBI-772361|ensembl:ENSMUSP00000001452	psi-mi:p04591-pro_0000038598(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10896058|imex:IM-23841-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6163428(chain-parent)	refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	chain-seq-start:449|chain-seq-end:500|crc64:9117D426B88A73CB	-	figure legend:Fig 4 B/D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/16	2015/07/01	rogid:maxbPg1zDMQXgRwCIidWTHov6wU11706	rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090	rigid:MP9a9dRz3x2L75KMvxWO++Wo3bo	false	binding-associated region:3-52|mutation:3-3|mutation disrupting interaction strength:43-47|15n label:?-?	sufficient binding region:210-380(IPR027409)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04591	uniprotkb:Q2NKZ1	intact:EBI-6163428	intact:EBI-9014155|ensembl:ENSBTAP00000016954	psi-mi:gag_hv1h2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:tcph_bovin(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCT-eta(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635304|imex:IM-23841-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6CQR|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6ECO|interpro:IPR036875|rcsb pdb:5FJB|rcsb pdb:5I1R|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR014817(Gag protein p6)|rcsb pdb:1TSQ|rcsb pdb:1TSU|refseq:NP_057850.1|rcsb pdb:6N3J|rcsb pdb:6N3U|rcsb pdb:5IND|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-164843|reactome:R-HSA-173107|reactome:R-HSA-174490|reactome:R-HSA-174495|reactome:R-HSA-175474|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|rcsb pdb:6ZDJ|rcsb pdb:5INC|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EC2|rcsb pdb:6ECN|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:3IYG|rcsb pdb:4B2T|ensembl:ENSBTAG00000012756(gene)|ensembl:ENSBTAT00000016954(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|refseq:NP_001039636.1|dip:DIP-58621N	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-7(molar)	2015/02/16	2015/02/16	rogid:nGwb9dDgtg+PAOx2OMo606pDync11706	rogid:oKJSeGaKwkh7+VROhDxSAqKLwb09913	intact-crc:06C852AC0604DB35|rigid:cDb7/LHJ4p8m7HKPavbfOfSUGxo	false	cross linker:424-424	cross linker:287-287	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04591	uniprotkb:Q3ZBH0	intact:EBI-6163428	intact:EBI-9014138|ensembl:ENSBTAP00000025496	psi-mi:gag_hv1h2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:tcpb_bovin(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635239|imex:IM-23841-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6CQR|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6ECO|interpro:IPR036875|rcsb pdb:5FJB|rcsb pdb:5I1R|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR014817(Gag protein p6)|rcsb pdb:1TSQ|rcsb pdb:1TSU|refseq:NP_057850.1|rcsb pdb:6N3J|rcsb pdb:6N3U|rcsb pdb:5IND|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-164843|reactome:R-HSA-173107|reactome:R-HSA-174490|reactome:R-HSA-174495|reactome:R-HSA-175474|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|rcsb pdb:6ZDJ|rcsb pdb:5INC|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EC2|rcsb pdb:6ECN|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:3IYG|go:"GO:0007339"(binding of sperm to zona pellucida)|rcsb pdb:3KTT|rcsb pdb:4A0O|rcsb pdb:4A0V|rcsb pdb:4A0W|rcsb pdb:4A13|rcsb pdb:4B2T|ensembl:ENSBTAG00000019156(gene)|ensembl:ENSBTAT00000025496(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|refseq:NP_001029411.1|dip:DIP-58618N	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-7(molar)	2015/02/16	2015/02/16	rogid:nGwb9dDgtg+PAOx2OMo606pDync11706	rogid:7R62XG84S7KYReGV1raM4Jwqt3U9913	intact-crc:38BC4A5A24CCF38E|rigid:q7j8jt28rPon/BIJWhPyCyZs/QM	false	cross linker:397-397	cross linker:284-284(IPR027409)	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04591	uniprotkb:Q3MHL7	intact:EBI-6163428	intact:EBI-9014129|ensembl:ENSBTAP00000069251|uniprotkb:A5D9B9	psi-mi:gag_hv1h2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:tcpz_bovin(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT-zeta(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Joachimiak et al. (2014)	imex:IM-23841|pubmed:25416944	taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10635264|imex:IM-23841-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6CQR|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6ECO|interpro:IPR036875|rcsb pdb:5FJB|rcsb pdb:5I1R|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR014817(Gag protein p6)|rcsb pdb:1TSQ|rcsb pdb:1TSU|refseq:NP_057850.1|rcsb pdb:6N3J|rcsb pdb:6N3U|rcsb pdb:5IND|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-164843|reactome:R-HSA-173107|reactome:R-HSA-174490|reactome:R-HSA-174495|reactome:R-HSA-175474|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|rcsb pdb:6ZDJ|rcsb pdb:5INC|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EC2|rcsb pdb:6ECN|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	ensembl:ENSBTAG00000008184(gene)|ensembl:ENSBTAT00000071259(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:3IYG|rcsb pdb:4B2T|refseq:NP_001029714.1|dip:DIP-58623N	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-7(molar)	2015/02/16	2015/02/16	rogid:nGwb9dDgtg+PAOx2OMo606pDync11706	rogid:8PxiuPfqpWUnJj1xldMWqG+5xM49913	intact-crc:09DA001D9E14544F|rigid:z1xy1/W0uJnpL1cpNZX2xk2+pLY	false	cross linker:110-110	cross linker:258-258	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)