#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BZS1-1	uniprotkb:P11309-1	intact:EBI-9695448|ensembl:ENSP00000365380	intact:EBI-1018629|ensembl:ENSP00000362608	psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name)	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2014)	pubmed:25096571|imex:IM-24353	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900440|imex:IM-24353-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent)	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	-	-	isoform-comment:Initiates from CTG codon.	figure legend:1 C|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/07	2018/10/22	rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	rigid:MVpoGXl9op4SWS4Y0MegC5sIeE8	false	ha tag:?-?|sufficient binding region:191-431|mutation decreasing interaction strength:422-422	flag tag:?-?|mutation disrupting interaction strength:67-67	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BZS1-1	uniprotkb:P11309-1	intact:EBI-9695448|ensembl:ENSP00000365380	intact:EBI-1018629|ensembl:ENSP00000362608	psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name)	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2014)	pubmed:25096571|imex:IM-24353	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900650|imex:IM-24353-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent)	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	-	-	isoform-comment:Initiates from CTG codon.	figure legend:4A|comment:Mutations of   Ser422    or Ser418 either increased or decreased  detection of Serine phosphorylated at residue 422.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/07	2018/10/22	rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	rigid:MVpoGXl9op4SWS4Y0MegC5sIeE8	false	flag tag:n-n|sufficient binding region:191-431|mutation decreasing interaction strength:422-422|mutation disrupting interaction strength:418-418|mutation increasing interaction strength:418-418|mutation decreasing interaction strength:418-418|mutation increasing interaction strength:418-418|O-phospho-L-serine:422-422	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9BZS1-1	uniprotkb:P11309-1	intact:EBI-9695448|ensembl:ENSP00000365380	intact:EBI-1018629|ensembl:ENSP00000362608	psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name)	psi-mi:p11309-1(display_long)|uniprotkb:Pim-1(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Li et al. (2014)	pubmed:25096571|imex:IM-24353	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900604|imex:IM-24353-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent)	intact:EBI-696621(pim1_human)|ensembl:ENSG00000137193(gene)|ensembl:ENST00000373509(transcript)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	isoform-comment:Initiates from CTG codon.	figure legend:1 E|comment:P11309-2 inhibits activity of Q9BZS1-1|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/07	2018/10/22	rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606	rogid:wB5jDvcfExiTZHKSMOeAOMHQacs9606	rigid:MVpoGXl9op4SWS4Y0MegC5sIeE8	false	maltose binding protein tag:?-?|O-phospho-L-serine:422-422	his tag:?-?|mutation disrupting interaction rate:67-67	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
ensembl:ENSG00000109471	uniprotkb:Q9BZS1-1	intact:EBI-1566859	intact:EBI-9695448|ensembl:ENSP00000365380	uniprotkb:IL2(gene name)|psi-mi:IL2(display_short)|ensembl:il2_human_gene(shortlabel)|psi-mi:ENSG00000109471(display_long)	psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Li et al. (2014)	pubmed:25096571|imex:IM-24353	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900767|imex:IM-24353-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_000577.2	ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent)	-	-	-	figure legend:4 D/E|causality statement:P11309 decreases binding of Q9BZS1  to ENSG00000109471.|comment:Ectopic expression of PIM1 reduced the accumulation of wild-type FOXP3, but not the S422A and S418A mutants.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2015/07/07	2016/02/03	-	rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606	-	false	sufficient binding region:?-?	flag tag:n-n|mutation increasing interaction strength:418-418|mutation decreasing interaction strength:422-422	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000109471	uniprotkb:Q9BZS1-1	intact:EBI-1566859	intact:EBI-9695448|ensembl:ENSP00000365380	uniprotkb:IL2(gene name)|psi-mi:IL2(display_short)|ensembl:il2_human_gene(shortlabel)|psi-mi:ENSG00000109471(display_long)	psi-mi:q9bzs1-1(display_long)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:JM2(orf name)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Li et al. (2014)	pubmed:25096571|imex:IM-24353	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900860|imex:IM-24353-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_000577.2	ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|intact:EBI-983719(isoform-parent)	-	-	-	figure legend:7 A|causality statement:"CHEBI:86453  increases binding of Q9BZS1-1  to ENSG00000109471."|agonist:"CHEBI:86453 - PIM1i - a specific inhibitor of PIM1."|causality statement:P11309  increases expression at RNA level of      ENSG00000109471.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t-cell)|taxid:9606(Homo sapiens)	-	2015/07/07	2016/02/03	-	rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606	-	false	sufficient binding region:?-?	flag tag:n-n|mutation increasing interaction strength:418-418|mutation decreasing interaction strength:422-422	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)