#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9JKX8 uniprotkb:Q9Z2C6 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 intact:EBI-10636370|uniprotkb:Q8C448|uniprotkb:Q8K4M0|ensembl:ENSMUSP00000052469 psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:upk1b_mouse(display_long)|uniprotkb:Upk1b(gene name)|psi-mi:Upk1b(display_short)|uniprotkb:Uroplakin Ib(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10636567|imex:IM-23963-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation) refseq:NP_849255.2|ensembl:ENSMUSG00000049436(gene)|ensembl:ENSMUST00000057767(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034766|refseq:XP_017172432.1 go:"GO:0005771"(multivesicular body) comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" - figure legend:6C/E|comment:positive control|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/02/18 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 rogid:VU2rKsfCjwWk9zLGI7LXzgrQohM10090 intact-crc:12E6A72C8B6E51C0|rigid:no0WgxkarbE/8OONVzS17nTajeM false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9JKX8 uniprotkb:Q6P8Y7 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 intact:EBI-10636102|uniprotkb:Q8BH14|uniprotkb:Q9D690|ensembl:ENSMUSP00000124063 psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:snx31_mouse(display_long)|uniprotkb:Snx31(gene name)|psi-mi:Snx31(display_short) psi-mi:"MI:0663"(confocal microscopy) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10636100|imex:IM-23963-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation) refseq:NP_079988.3|refseq:NP_001333951.1|ensembl:ENSMUSG00000013611(gene)|ensembl:ENSMUST00000161202(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|interpro:IPR037831|interpro:IPR040842|dip:DIP-60339N go:"GO:0005771"(multivesicular body) comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" - figure legend:1D, 6 D/F,9|comment:Mice with the Buff -Vps33a D251E mutation show an augmented interaction.|antagonist:UPII-knockout|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/03/05 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 rogid:0S4JVP8Pfyq21pDU6jrPfpZu97410090 intact-crc:BF1312CE15D31D33|rigid:ZDAwO1t2JMrx4rfTqrfvuoXx63k false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9JKX8 uniprotkb:Q6P8Y7 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 intact:EBI-10636102|uniprotkb:Q8BH14|uniprotkb:Q9D690|ensembl:ENSMUSP00000124063 psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:snx31_mouse(display_long)|uniprotkb:Snx31(gene name)|psi-mi:Snx31(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10636268|imex:IM-23963-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation) refseq:NP_079988.3|refseq:NP_001333951.1|ensembl:ENSMUSG00000013611(gene)|ensembl:ENSMUST00000161202(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|interpro:IPR037831|interpro:IPR040842|dip:DIP-60339N go:"GO:0005771"(multivesicular body) comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" - figure legend:3G|comment:Co-localization is seen at the limiting membranes of multivesicular bodies|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/02/17 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 rogid:0S4JVP8Pfyq21pDU6jrPfpZu97410090 intact-crc:826345A66970C7CB|rigid:ZDAwO1t2JMrx4rfTqrfvuoXx63k false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q6P8Y7 uniprotkb:Q9JKX8 intact:EBI-10636102|uniprotkb:Q8BH14|uniprotkb:Q9D690|ensembl:ENSMUSP00000124063 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 psi-mi:snx31_mouse(display_long)|uniprotkb:Snx31(gene name)|psi-mi:Snx31(display_short) psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10636330|imex:IM-23963-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079988.3|refseq:NP_001333951.1|ensembl:ENSMUSG00000013611(gene)|ensembl:ENSMUST00000161202(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|interpro:IPR037831|interpro:IPR040842|dip:DIP-60339N refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation) go:"GO:0005771"(multivesicular body) - comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" figure legend:"6A (B)"|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/03/23 rogid:0S4JVP8Pfyq21pDU6jrPfpZu97410090 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 intact-crc:193ECEA0660AA1A2|rigid:D6b5FT1F5DEYG00Z38IkG7fyFKU false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q6P8Y7 uniprotkb:Q9Z2C6 intact:EBI-10636102|uniprotkb:Q8BH14|uniprotkb:Q9D690|ensembl:ENSMUSP00000124063 intact:EBI-10636370|uniprotkb:Q8C448|uniprotkb:Q8K4M0|ensembl:ENSMUSP00000052469 psi-mi:snx31_mouse(display_long)|uniprotkb:Snx31(gene name)|psi-mi:Snx31(display_short) psi-mi:upk1b_mouse(display_long)|uniprotkb:Upk1b(gene name)|psi-mi:Upk1b(display_short)|uniprotkb:Uroplakin Ib(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10636330|imex:IM-23963-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079988.3|refseq:NP_001333951.1|ensembl:ENSMUSG00000013611(gene)|ensembl:ENSMUST00000161202(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|interpro:IPR037831|interpro:IPR040842|dip:DIP-60339N refseq:NP_849255.2|ensembl:ENSMUSG00000049436(gene)|ensembl:ENSMUST00000057767(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034766|refseq:XP_017172432.1 go:"GO:0005771"(multivesicular body) - - figure legend:"6A (B)"|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/03/23 rogid:0S4JVP8Pfyq21pDU6jrPfpZu97410090 rogid:VU2rKsfCjwWk9zLGI7LXzgrQohM10090 intact-crc:193ECEA0660AA1A2|rigid:D6b5FT1F5DEYG00Z38IkG7fyFKU false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9JKX8 uniprotkb:Q9Z2C6 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 intact:EBI-10636370|uniprotkb:Q8C448|uniprotkb:Q8K4M0|ensembl:ENSMUSP00000052469 psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:upk1b_mouse(display_long)|uniprotkb:Upk1b(gene name)|psi-mi:Upk1b(display_short)|uniprotkb:Uroplakin Ib(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-10636608|imex:IM-23963-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation) refseq:NP_849255.2|ensembl:ENSMUSG00000049436(gene)|ensembl:ENSMUST00000057767(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034766|refseq:XP_017172432.1 go:"GO:0005771"(multivesicular body) comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" - figure legend:6 G/I|comment:positive control|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/03/05 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 rogid:VU2rKsfCjwWk9zLGI7LXzgrQohM10090 intact-crc:3B43F6A857396EA3|rigid:no0WgxkarbE/8OONVzS17nTajeM false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9JKX8 uniprotkb:Q6P8Y7 intact:EBI-7947322|uniprotkb:Q27QV3|intact:UNK-5550075|ensembl:ENSMUSP00000023070 intact:EBI-10636102|uniprotkb:Q8BH14|uniprotkb:Q9D690|ensembl:ENSMUSP00000124063 psi-mi:upk3a_mouse(display_long)|uniprotkb:Upk3a(gene name)|psi-mi:Upk3a(display_short)|uniprotkb:Upk3(gene name synonym)|uniprotkb:Uroplakin III(gene name synonym) psi-mi:snx31_mouse(display_long)|uniprotkb:Snx31(gene name)|psi-mi:Snx31(display_short) psi-mi:"MI:0813"(proximity ligation assay) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-10636611|imex:IM-23963-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075967.2|ensembl:ENSMUSG00000022435(gene)|ensembl:ENSMUST00000023070(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015840"(urea transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060157"(urinary bladder development)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR024825|interpro:IPR024831|go:"GO:0030855"(epithelial cell differentiation) refseq:NP_079988.3|refseq:NP_001333951.1|ensembl:ENSMUSG00000013611(gene)|ensembl:ENSMUST00000161202(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|interpro:IPR037831|interpro:IPR040842|dip:DIP-60339N go:"GO:0005771"(multivesicular body) comment:mint|function:"Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence" - figure legend:6 H/J|comment:Mice with the Buff -Vps33a D251E mutation show an augmented interaction.|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-urothelium)|taxid:10090(mouse urothelium or uroepithelium) - 2015/02/13 2015/02/18 rogid:CiyyouOJKlEQ910i9NMr+Q5yGDw10090 rogid:0S4JVP8Pfyq21pDU6jrPfpZu97410090 intact-crc:0D21FC32C7731B81|rigid:ZDAwO1t2JMrx4rfTqrfvuoXx63k false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:26034" uniprotkb:Q6P8Y7 intact:EBI-8802613 intact:EBI-10636102|uniprotkb:Q8BH14|uniprotkb:Q9D690|ensembl:ENSMUSP00000124063 psi-mi:phosphatidylinositol-3-phosphate(display_short)|psi-mi:"CHEBI:26034"(display_long)|intact:phosphatidylinositol 3-phosphates(synonym)|intact:"PI(3)P"(synonym)|intact:PtdIns3P(synonym) psi-mi:snx31_mouse(display_long)|uniprotkb:Snx31(gene name)|psi-mi:Snx31(display_short) psi-mi:"MI:0049"(filter binding) Vieira et al. (2014) imex:IM-23963|pubmed:24914955 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10636713|imex:IM-23963-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_079988.3|refseq:NP_001333951.1|ensembl:ENSMUSG00000013611(gene)|ensembl:ENSMUST00000161202(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|interpro:IPR037831|interpro:IPR040842|dip:DIP-60339N - - - figure legend:10|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/13 2015/03/19 - rogid:0S4JVP8Pfyq21pDU6jrPfpZu97410090 intact-crc:B502C0997881CFCD false - ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)