#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8NEB9	uniprotkb:P38646	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893857|imex:IM-24315-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:dygJxyRIxy8H82Mec6IF+tzpIOg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NEB9	uniprotkb:Q9P2Y5	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2952704|uniprotkb:B3KTC1|ensembl:ENSP00000348455|uniprotkb:O00392	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:uvrag_human(display_long)|uniprotkb:UVRAG(gene name)|psi-mi:UVRAG(display_short)|uniprotkb:p63(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893857|imex:IM-24315-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q9P2Y5|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-9679504|reactome:R-HSA-9694676|ensembl:ENSG00000198382(gene)|ensembl:ENST00000356136(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|refseq:NP_003360.2|ensembl:ENSP00000348455|ensembl:ENST00000531818|ensembl:ENSP00000434082|ensembl:ENST00000532130|ensembl:ENSP00000436270|ensembl:ENST00000533454|ensembl:ENSP00000431256|dip:DIP-48652N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:TDc74eSYcSe2UJdNnKbFv5EBziE9606	rigid:dygJxyRIxy8H82Mec6IF+tzpIOg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NEB9	uniprotkb:Q6ZNE5	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2690371|uniprotkb:Q32MK7|uniprotkb:A6NJE4|uniprotkb:Q32MK8|uniprotkb:O94920|uniprotkb:A8K9U5|uniprotkb:B7ZWP5|ensembl:ENSP00000247178	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:bakor_human(display_long)|uniprotkb:KIAA0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:ATG14(gene name)|psi-mi:ATG14(display_short)|uniprotkb:ATG14L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893857|imex:IM-24315-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:XP_011534865.1|refseq:NP_055739.2|ensembl:ENSG00000126775(gene)|ensembl:ENST00000247178(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|rcsb pdb:6HOL|reactome:R-HSA-1632852|dip:DIP-48651N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:hAzH6syRuwo7HuR/MOXekHPrkJc9606	rigid:dygJxyRIxy8H82Mec6IF+tzpIOg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NEB9	uniprotkb:Q14457	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893857|imex:IM-24315-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	rigid:dygJxyRIxy8H82Mec6IF+tzpIOg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NEB9	uniprotkb:Q96F24	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893857|imex:IM-24315-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:dygJxyRIxy8H82Mec6IF+tzpIOg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NEB9	uniprotkb:Q99570	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893857|imex:IM-24315-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rigid:dygJxyRIxy8H82Mec6IF+tzpIOg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96F24	uniprotkb:Q6ZNE5	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-2690371|uniprotkb:Q32MK7|uniprotkb:A6NJE4|uniprotkb:Q32MK8|uniprotkb:O94920|uniprotkb:A8K9U5|uniprotkb:B7ZWP5|ensembl:ENSP00000247178	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:bakor_human(display_long)|uniprotkb:KIAA0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:ATG14(gene name)|psi-mi:ATG14(display_short)|uniprotkb:ATG14L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893877|imex:IM-24315-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:XP_011534865.1|refseq:NP_055739.2|ensembl:ENSG00000126775(gene)|ensembl:ENST00000247178(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|rcsb pdb:6HOL|reactome:R-HSA-1632852|dip:DIP-48651N	-	-	-	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/25	2015/06/25	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:hAzH6syRuwo7HuR/MOXekHPrkJc9606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q14457	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893877|imex:IM-24315-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	-	-	-	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/25	2015/06/25	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q99570	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893877|imex:IM-24315-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	-	-	-	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/25	2015/06/25	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q8NEB9	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893877|imex:IM-24315-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	-	-	-	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/25	2015/06/25	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NEB9	uniprotkb:Q96F24	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893895|imex:IM-24315-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:2A and 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:E/fpOzev1RQITEw919gYyHhav/E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q6ZNE5	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-2690371|uniprotkb:Q32MK7|uniprotkb:A6NJE4|uniprotkb:Q32MK8|uniprotkb:O94920|uniprotkb:A8K9U5|uniprotkb:B7ZWP5|ensembl:ENSP00000247178	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:bakor_human(display_long)|uniprotkb:KIAA0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:ATG14(gene name)|psi-mi:ATG14(display_short)|uniprotkb:ATG14L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893899|imex:IM-24315-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:XP_011534865.1|refseq:NP_055739.2|ensembl:ENSG00000126775(gene)|ensembl:ENST00000247178(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|rcsb pdb:6HOL|reactome:R-HSA-1632852|dip:DIP-48651N	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/30	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:hAzH6syRuwo7HuR/MOXekHPrkJc9606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q14457	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893899|imex:IM-24315-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/30	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q99570	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893899|imex:IM-24315-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/30	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96F24	uniprotkb:Q8NEB9	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893899|imex:IM-24315-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/30	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rigid:KiBaur+ZJtuA2lfhGT7qy8Ta0rY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NEB9	uniprotkb:Q96F24	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893989|imex:IM-24315-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:5C and D|comment:Neither endogenous  nor overexpressed UVRAG was detected to associate.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:E/fpOzev1RQITEw919gYyHhav/E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NEB9	uniprotkb:Q96F24	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893993|imex:IM-24315-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:+tAaBhhkniNyrGZLaF//oNROnII	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NEB9	uniprotkb:Q9P2Y5	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2952704|uniprotkb:B3KTC1|ensembl:ENSP00000348455|uniprotkb:O00392	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:uvrag_human(display_long)|uniprotkb:UVRAG(gene name)|psi-mi:UVRAG(display_short)|uniprotkb:p63(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893993|imex:IM-24315-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q9P2Y5|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-9679504|reactome:R-HSA-9694676|ensembl:ENSG00000198382(gene)|ensembl:ENST00000356136(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|refseq:NP_003360.2|ensembl:ENSP00000348455|ensembl:ENST00000531818|ensembl:ENSP00000434082|ensembl:ENST00000532130|ensembl:ENSP00000436270|ensembl:ENST00000533454|ensembl:ENSP00000431256|dip:DIP-48652N	-	-	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:TDc74eSYcSe2UJdNnKbFv5EBziE9606	rigid:+tAaBhhkniNyrGZLaF//oNROnII	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NEB9	uniprotkb:Q96F24	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10894014|imex:IM-24315-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:+tAaBhhkniNyrGZLaF//oNROnII	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NEB9	uniprotkb:Q9P2Y5	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2952704|uniprotkb:B3KTC1|ensembl:ENSP00000348455|uniprotkb:O00392	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:uvrag_human(display_long)|uniprotkb:UVRAG(gene name)|psi-mi:UVRAG(display_short)|uniprotkb:p63(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10894014|imex:IM-24315-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q9P2Y5|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-9679504|reactome:R-HSA-9694676|ensembl:ENSG00000198382(gene)|ensembl:ENST00000356136(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|refseq:NP_003360.2|ensembl:ENSP00000348455|ensembl:ENST00000531818|ensembl:ENSP00000434082|ensembl:ENST00000532130|ensembl:ENSP00000436270|ensembl:ENST00000533454|ensembl:ENSP00000431256|dip:DIP-48652N	-	-	-	figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:TDc74eSYcSe2UJdNnKbFv5EBziE9606	rigid:+tAaBhhkniNyrGZLaF//oNROnII	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96F24	uniprotkb:Q99570	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893915|imex:IM-24315-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	-	-	-	figure legend:3A|comment:PIK3R4/Vps15 is required for association of PIK3C3/Vps34|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rigid:qL1djBtVQ9dJ5G8uXdGZUbtKi3g	false	ha tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96F24	uniprotkb:Q8NEB9	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893915|imex:IM-24315-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	-	-	-	figure legend:3A|comment:PIK3R4/Vps15 is required for association of PIK3C3/Vps34|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rigid:qL1djBtVQ9dJ5G8uXdGZUbtKi3g	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99570	uniprotkb:Q96F24	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893927|imex:IM-24315-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:yhfYPV9r9CvmqqjLu3+mkJKu4oo	false	v5 tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99570	uniprotkb:Q8NEB9	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893937|imex:IM-24315-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	-	-	-	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rigid:qL1djBtVQ9dJ5G8uXdGZUbtKi3g	false	v5 tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99570	uniprotkb:Q96F24	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893937|imex:IM-24315-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:qL1djBtVQ9dJ5G8uXdGZUbtKi3g	false	v5 tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99570	uniprotkb:Q96F24	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893949|imex:IM-24315-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:yhfYPV9r9CvmqqjLu3+mkJKu4oo	false	v5 tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NEB9	uniprotkb:Q99570	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893957|imex:IM-24315-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	-	-	-	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rigid:qL1djBtVQ9dJ5G8uXdGZUbtKi3g	false	myc tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NEB9	uniprotkb:Q96F24	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893957|imex:IM-24315-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/25	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:qL1djBtVQ9dJ5G8uXdGZUbtKi3g	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99570	uniprotkb:Q96F24	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	intact:EBI-2362014|uniprotkb:Q86UR2|uniprotkb:Q96NP6|uniprotkb:Q9H0S9|uniprotkb:Q9H2I2|uniprotkb:A6PW36|uniprotkb:B4DWS0|ensembl:ENSP00000277746	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:nrbf2_human(display_long)|uniprotkb:NRBF2(gene name)|psi-mi:NRBF2(display_short)|uniprotkb:COPR(gene name synonym)|uniprotkb:Comodulator of PPAR and RXR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10893979|imex:IM-24315-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	refseq:NP_110386.2|refseq:NP_001269334.1|ensembl:ENSG00000148572(gene)|ensembl:ENST00000277746(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0006914"(autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0043550"(regulation of lipid kinase activity)|interpro:IPR015056(Protein of unknown function DUF1875)|interpro:IPR033393|interpro:IPR039679|rcsb pdb:4ZEY|reactome:R-HSA-383280	-	-	-	figure legend:5A and B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/25	2015/06/30	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rogid:PWt0/5LsBllvyqOhdHX0ulbq4mc9606	rigid:yhfYPV9r9CvmqqjLu3+mkJKu4oo	false	sufficient binding region:1-971|35s radiolabel:?-?|sufficient binding region:1092-1358	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8NEB9	uniprotkb:Q9P2Y5	intact:EBI-1056470|uniprotkb:Q15134|ensembl:ENSP00000262039	intact:EBI-2952704|uniprotkb:B3KTC1|ensembl:ENSP00000348455|uniprotkb:O00392	psi-mi:pk3c3_human(display_long)|uniprotkb:PIK3C3(gene name)|psi-mi:PIK3C3(display_short)|uniprotkb:Phosphoinositide-3-kinase class 3(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase p100 subunit(gene name synonym)|uniprotkb:VPS34(gene name synonym)|uniprotkb:hVps34(gene name synonym)	psi-mi:uvrag_human(display_long)|uniprotkb:UVRAG(gene name)|psi-mi:UVRAG(display_short)|uniprotkb:p63(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2014)	pubmed:24785657|imex:IM-24315	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10894006|imex:IM-24315-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002638.2|ensembl:ENSG00000078142(gene)|ensembl:ENST00000262039(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043201"(response to leucine)|go:"GO:0044754"(autolysosome)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|rcsb pdb:3IHY|rcsb pdb:3LS8|rcsb pdb:4OYS|rcsb pdb:4PH4|rcsb pdb:4UWF|rcsb pdb:4UWG|rcsb pdb:4UWH|rcsb pdb:4UWK|rcsb pdb:4UWL|rcsb pdb:5ANL|rcsb pdb:5ENN|rcsb pdb:6I3U|rcsb pdb:6YKG|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-42272N	go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q9P2Y5|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-9679504|reactome:R-HSA-9694676|ensembl:ENSG00000198382(gene)|ensembl:ENST00000356136(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|refseq:NP_003360.2|ensembl:ENSP00000348455|ensembl:ENST00000531818|ensembl:ENSP00000434082|ensembl:ENST00000532130|ensembl:ENSP00000436270|ensembl:ENST00000533454|ensembl:ENSP00000431256|dip:DIP-48652N	-	-	-	figure legend:5D|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/06/25	2015/06/30	rogid:sF4quAbxXhvZQ/Ud6Ra0VSWgbNQ9606	rogid:TDc74eSYcSe2UJdNnKbFv5EBziE9606	rigid:yM6Z+oyTwNxi5VsKpvhgI1Fu3vY	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)