#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NP73-4 uniprotkb:X5D7T5 intact:EBI-10186621|ensembl:ENSP00000251943|ensembl:ENSP00000392990|ensembl:ENSP00000481509 intact:EBI-21246658 psi-mi:q9np73-4(display_long)|uniprotkb:Asparagine-linked glycosylation 13 homolog(gene name synonym)|uniprotkb:CXorf45(gene name synonym)|uniprotkb:GLT28D1(gene name synonym)|uniprotkb:Glycosyltransferase 28 domain-containing protein 1(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine transferase subunit ALG13 homolog(gene name synonym)|uniprotkb:MDS031(orf name)|uniprotkb:ALG13(gene name)|psi-mi:ALG13(display_short) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246674|imex:IM-24135-1341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-947892(isoform-parent)|ensembl:ENSG00000101901(gene)|ensembl:ENST00000251943(transcript)|ensembl:ENST00000436609(transcript)|ensembl:ENST00000621367(transcript)|uniprotkb:Q9NP73-4(isoform-parent)|entrezgene/locuslink:79868(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kdF/foB7v2Vv5e1Qene8EAB2wig9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:wTRxzrAVpwrIArHaFJYBPW3+2dk false sufficient binding region:496-954 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:X5D7T5 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-21246658 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246692|imex:IM-24135-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:wQbUGqhmKcSYpdOTnS834sPGfZQ false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43186 uniprotkb:X5D7T5 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 intact:EBI-21246658 psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246702|imex:IM-24135-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:IhD6xOkibwo2ZxFwaan2ZGEukFM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92567-2 uniprotkb:X5D7T5 intact:EBI-11978259|ensembl:ENSP00000348852 intact:EBI-21246658 psi-mi:q92567-2(display_long)|uniprotkb:FAM168A(gene name)|psi-mi:FAM168A(display_short)|uniprotkb:KIAA0280(gene name synonym)|uniprotkb:TCRP1(gene name synonym)|uniprotkb:Tongue cancer chemotherapy resistance-associated protein 1(gene name synonym) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246710|imex:IM-24135-781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7957930(isoform-parent)|uniprotkb:Q92567-2(isoform-parent)|ensembl:ENSG00000054965(gene)|ensembl:ENST00000356467(transcript)|entrezgene/locuslink:23201(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:CBYXLUO3q4TBqLJNnXUVA6rk46M9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:0jPtGRWp78cm0inP4QnEq0mbI6E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96LI6 uniprotkb:X5D7T5 intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549 intact:EBI-21246658 psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246718|imex:IM-24135-1345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:W6+dazGoHAl7jJdYvITROz5ixrI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P86479 uniprotkb:X5D7T5 intact:EBI-10172814|uniprotkb:Q8N7V5|ensembl:ENSP00000438757|ensembl:ENSP00000480729 intact:EBI-21246658 psi-mi:pr20c_human(display_long)|uniprotkb:PRR20C(gene name)|psi-mi:PRR20C(display_short) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246726|imex:IM-24135-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016855016.1|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|ensembl:ENSG00000229665(gene)|ensembl:ENST00000544357(transcript)|ensembl:ENST00000614894(transcript)|interpro:IPR031439|entrezgene/locuslink:122183(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:EX1C/VPY7gl9iLunzPN/W6/qV2Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14503 uniprotkb:X5DP44 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 intact:EBI-21246742 psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246758|imex:IM-24135-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108|entrezgene/locuslink:8553(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:Ccw0F+wbvufg63/F3+/2Kpid11Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:X5DP44 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-21246742 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246766|imex:IM-24135-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:JDbl7Cd1F6Cvk14Z6frZl6U9QaM false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92567-2 uniprotkb:X5DP44 intact:EBI-11978259|ensembl:ENSP00000348852 intact:EBI-21246742 psi-mi:q92567-2(display_long)|uniprotkb:FAM168A(gene name)|psi-mi:FAM168A(display_short)|uniprotkb:KIAA0280(gene name synonym)|uniprotkb:TCRP1(gene name synonym)|uniprotkb:Tongue cancer chemotherapy resistance-associated protein 1(gene name synonym) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246776|imex:IM-24135-1161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7957930(isoform-parent)|uniprotkb:Q92567-2(isoform-parent)|ensembl:ENSG00000054965(gene)|ensembl:ENST00000356467(transcript)|entrezgene/locuslink:23201(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:CBYXLUO3q4TBqLJNnXUVA6rk46M9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:XwN2y/XZlfqheiJnO4/d2tO4oZY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96LI6 uniprotkb:X5DP44 intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549 intact:EBI-21246742 psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246784|imex:IM-24135-785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:mBeZE+hbrVAC9pIuS0Xh7AGqrOU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P86479 uniprotkb:X5DP44 intact:EBI-10172814|uniprotkb:Q8N7V5|ensembl:ENSP00000438757|ensembl:ENSP00000480729 intact:EBI-21246742 psi-mi:pr20c_human(display_long)|uniprotkb:PRR20C(gene name)|psi-mi:PRR20C(display_short) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246792|imex:IM-24135-1181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016855016.1|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|ensembl:ENSG00000229665(gene)|ensembl:ENST00000544357(transcript)|ensembl:ENST00000614894(transcript)|interpro:IPR031439|entrezgene/locuslink:122183(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:bXL9XtS37gIWiLckD5d4xPzOSBs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:X5DP44 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-21246742 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246800|imex:IM-24135-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:rwUpwiOpBOipeFtqqxMDMgK0kjI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14503 uniprotkb:X5D7T5 intact:EBI-711810|uniprotkb:Q96TD3|ensembl:ENSP00000256495 intact:EBI-21246658 psi-mi:bhe40_human(display_long)|uniprotkb:BHLHE40(gene name)|psi-mi:BHLHE40(display_short)|uniprotkb:Differentially expressed in chondrocytes protein 1(gene name synonym)|uniprotkb:Enhancer-of-split and hairy-related protein 2(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein(gene name synonym)|uniprotkb:BHLHB2(gene name synonym)|uniprotkb:DEC1(gene name synonym)|uniprotkb:SHARP2(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 2(gene name synonym) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246684|imex:IM-24135-1343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134107(gene)|ensembl:ENST00000256495(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_003661.1|dip:DIP-36698N|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:O14503|reactome:R-HSA-1368108|entrezgene/locuslink:8553(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JZrZ1Yo2PF33s9Lf8rLTHCqoptk9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:nK6zrg+U678w50UXXFTQPBXL/j0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:X5D7T5 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-21246658 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246734|imex:IM-24135-783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rigid:GSdGyyjFdEfaIjDKdzdeJMwg1hc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75553-4 uniprotkb:Q9NWB1-5 intact:EBI-21246842 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:o75553-4(display_long)|uniprotkb:DAB1(gene name)|psi-mi:DAB1(display_short) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246847|imex:IM-24135-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7875264(isoform-parent)|uniprotkb:O75553-4(isoform-parent)|entrezgene/locuslink:1600(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Hj5jQkMh4Xq5UbZITFQzmK4QEaU9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:+cZAe02EE9vEupIWx8ZQLiRtUq4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43186 uniprotkb:Q9NWB1-5 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246834|imex:IM-24135-789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:fXEtN27Tv6KEUGx5Ddhg2uKyXOc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:Q9NWB1-5 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246824|imex:IM-24135-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:+6zMuG35P0ldPWuwyfcoECY64AE false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NWB1-5 uniprotkb:Q9NWB1-5 intact:EBI-12123390|ensembl:ENSP00000347855 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246816|imex:IM-24135-787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:Er1V5Lr15WMOMxk4y8zbQoECQ7Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BQY4 uniprotkb:X5DP44 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-21246742 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:x5dp44_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246808|imex:IM-24135-1183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) refseq:XP_011520850.1|interpro:IPR025670|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0008380"(RNA splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:Fos/CxjaZL0DmFPRq8Vo1sxhdLQ9606 rigid:hZv6ZbycfUl2A/lyYRRVkh/hnjg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q9NWB1-5 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246855|imex:IM-24135-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:NgtSDqK7Vclue9pEEnvOHtfGhJw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92567-2 uniprotkb:Q9NWB1-5 intact:EBI-11978259|ensembl:ENSP00000348852 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:q92567-2(display_long)|uniprotkb:FAM168A(gene name)|psi-mi:FAM168A(display_short)|uniprotkb:KIAA0280(gene name synonym)|uniprotkb:TCRP1(gene name synonym)|uniprotkb:Tongue cancer chemotherapy resistance-associated protein 1(gene name synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246863|imex:IM-24135-1347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7957930(isoform-parent)|uniprotkb:Q92567-2(isoform-parent)|ensembl:ENSG00000054965(gene)|ensembl:ENST00000356467(transcript)|entrezgene/locuslink:23201(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:CBYXLUO3q4TBqLJNnXUVA6rk46M9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:vMs51pBLNvJSENubJirk87UEtyI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96LI6 uniprotkb:Q9NWB1-5 intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246871|imex:IM-24135-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:LkxklUJL8EQ9wskyOHnVJaiNUq8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y5V3 uniprotkb:Q9NWB1-5 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246879|imex:IM-24135-1185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:FA7hN7mx2R508xSjoBPIaA05KZw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P86479 uniprotkb:Q9NWB1-5 intact:EBI-10172814|uniprotkb:Q8N7V5|ensembl:ENSP00000438757|ensembl:ENSP00000480729 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:pr20c_human(display_long)|uniprotkb:PRR20C(gene name)|psi-mi:PRR20C(display_short) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246887|imex:IM-24135-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016855016.1|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|ensembl:ENSG00000229665(gene)|ensembl:ENST00000544357(transcript)|ensembl:ENST00000614894(transcript)|interpro:IPR031439|entrezgene/locuslink:122183(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:rOhY7tUATNtAqYQg+YBF7EoeZpk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:Q9NWB1-5 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246895|imex:IM-24135-1187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:eU5I7/LbQ448Q1ydYsazfK6EVqs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BQY4 uniprotkb:Q9NWB1-5 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246903|imex:IM-24135-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:j/6bNuwP78zO2V/yFXFnZE2msxs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IZU0 uniprotkb:Q9NPH0 intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495 intact:EBI-717738|uniprotkb:Q59G61|uniprotkb:Q5T490|uniprotkb:Q6IAQ3|uniprotkb:Q7LG81|uniprotkb:Q9UIG6|ensembl:ENSP00000463574|uniprotkb:X5D289 psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short) psi-mi:ppa6_human(display_long)|uniprotkb:Acid phosphatase 6, lysophosphatidic(gene name synonym)|uniprotkb:Acid phosphatase-like protein 1(gene name synonym)|uniprotkb:PACPL1(gene name synonym)|uniprotkb:ACP6(gene name)|psi-mi:ACP6(display_short)|uniprotkb:ACPL1(gene name synonym)|uniprotkb:LPAP(gene name synonym)|uniprotkb:UNQ205/PRO231(orf name) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246911|imex:IM-24135-1189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity) refseq:NP_057445.4|ensembl:ENSG00000162836(gene)|ensembl:ENST00000583509(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:2001311"(lysobisphosphatidic acid metabolic process)|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|interpro:IPR033379|rcsb pdb:4JOB|rcsb pdb:4JOC|rcsb pdb:4JOD|reactome:R-HSA-1483166|entrezgene/locuslink:51205(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606 rogid:jw5JDM3ZE8dMk/NtpVFBwocZWYg9606 rigid:SBxTjdiF/vFHflLYA8BdQYf8U40 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:P07550 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-491169|uniprotkb:Q9UH95|uniprotkb:Q9UHA1|uniprotkb:O14823|uniprotkb:O14824|uniprotkb:O14825|uniprotkb:O14826|uniprotkb:Q4JG18|uniprotkb:Q8NEQ9|uniprotkb:Q9UMZ5|uniprotkb:Q6P4D8|uniprotkb:B0LPE4|uniprotkb:B2R7X2|uniprotkb:Q53GA6|uniprotkb:Q6GMT4|uniprotkb:Q96EC3|uniprotkb:Q9UCZ0|uniprotkb:Q9UCZ1|uniprotkb:Q9UCZ2|uniprotkb:Q9UCZ3|ensembl:ENSP00000305372 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:adrb2_human(display_long)|uniprotkb:Beta-2 adrenoreceptor(gene name synonym)|uniprotkb:ADRB2(gene name)|psi-mi:ADRB2(display_short)|uniprotkb:ADRB2R(gene name synonym)|uniprotkb:B2AR(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246919|imex:IM-24135-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) refseq:NP_000015.1|ensembl:ENSG00000169252(gene)|ensembl:ENST00000305988(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002025"(norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004941"(beta2-adrenergic receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007171"(activation of transmembrane receptor protein tyrosine kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009409"(response to cold)|go:"GO:0010008"(endosome membrane)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031649"(heat generation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0061885"(positive regulation of mini excitatory postsynaptic potential)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0051380"(norepinephrine binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000332(Adrenergic receptor, beta 2)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P07550|rcsb pdb:1GQ4|rcsb pdb:2R4R|rcsb pdb:2R4S|rcsb pdb:2RH1|rcsb pdb:3D4S|rcsb pdb:3KJ6|rcsb pdb:3NY8|rcsb pdb:3NY9|rcsb pdb:3NYA|rcsb pdb:3P0G|rcsb pdb:3PDS|rcsb pdb:3SN6|rcsb pdb:4GBR|rcsb pdb:4LDE|rcsb pdb:4LDL|rcsb pdb:4LDO|rcsb pdb:4QKX|rcsb pdb:5D5A|rcsb pdb:5D5B|rcsb pdb:5D6L|rcsb pdb:5JQH|rcsb pdb:5X7D|rcsb pdb:6E67|rcsb pdb:6KR8|rcsb pdb:6MXT|rcsb pdb:6N48|rcsb pdb:6NI3|rcsb pdb:6OBA|rcsb pdb:6PRZ|rcsb pdb:6PS0|rcsb pdb:6PS1|rcsb pdb:6PS2|rcsb pdb:6PS3|rcsb pdb:6PS4|rcsb pdb:6PS5|rcsb pdb:6PS6|rcsb pdb:7BZ2|rcsb pdb:7DHI|rcsb pdb:7DHR|reactome:R-HSA-390696|reactome:R-HSA-418555|reactome:R-HSA-5689880|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9660821|dip:DIP-33948N|entrezgene/locuslink:154(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:+pZmEUm9SKroeqpa7uI44Bz18zo9606 rigid:XlakscT83qZirpF2AkIntvnHFog false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:P30566 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-2511688|ensembl:ENSP00000485525|uniprotkb:B0QY76|uniprotkb:O75495|uniprotkb:Q5TI34 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:pur8_human(display_long)|uniprotkb:ADSL(gene name)|psi-mi:ADSL(display_short)|uniprotkb:AMPS(gene name synonym)|uniprotkb:Adenylosuccinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246927|imex:IM-24135-981 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) go:"GO:0014850"(response to muscle activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")|ensembl:ENSG00000239900(gene)|ensembl:ENST00000623063(transcript)|interpro:IPR000362(Fumarate lyase)|interpro:IPR004769(Adenylosuccinate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR019468|interpro:IPR020557|interpro:IPR022761|rcsb pdb:2J91|rcsb pdb:2VD6|rcsb pdb:4FFX|rcsb pdb:4FLC|reactome:R-HSA-73817|go:"GO:0001666"(response to hypoxia)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009060"(aerobic respiration)|refseq:NP_000017.1|refseq:NP_001116850.1|refseq:NP_001304852.1|entrezgene/locuslink:158(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:yBhDdHJgZN1NJDpN2ivKLI4oUG09606 rigid:k7vnjOwiYn7/9e9eif36nTSrF2k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5D7W4 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21246935 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5d7w4_human(display_long)|uniprotkb:ADSL(gene name)|psi-mi:ADSL(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246942|imex:IM-24135-1349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) refseq:NP_001304852.1|interpro:IPR024083|go:"GO:0016829"(lyase activity)|entrezgene/locuslink:158(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:a1xH6e+xLRYiDVh7Fs18si2Oatg9606 rigid:vmn3s1X6qAw+csg5i+HB8t5lBBU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5DP48 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21246950 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5dp48_human(display_long)|uniprotkb:ADSL(gene name)|psi-mi:ADSL(display_short)|uniprotkb:Adenylosuccinate lyase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246962|imex:IM-24135-1351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) interpro:IPR024083|interpro:IPR020557|interpro:IPR000362(Fumarate lyase)|interpro:IPR022761|interpro:IPR008948(L-Aspartase-like)|interpro:IPR004769(Adenylosuccinate lyase)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")|entrezgene/locuslink:158(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:VR/z2Xx7XOjpR4DVYsqxLH268aE9606 rigid:7dThUN/Fq+88LYKrvU2XcpoV7Vg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43364 uniprotkb:P51649 intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358 intact:EBI-2684180|uniprotkb:Q546H9|uniprotkb:B2RD26|uniprotkb:G5E949|uniprotkb:Q8N3W6|ensembl:ENSP00000350191 psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym) psi-mi:ssdh_human(display_long)|uniprotkb:SSADH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 5 member A1(gene name synonym)|uniprotkb:"NAD(+)-dependent succinic semialdehyde dehydrogenase"(gene name synonym)|uniprotkb:ALDH5A1(gene name)|psi-mi:ALDH5A1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246970|imex:IM-24135-983 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity) refseq:NP_001071.1|refseq:NP_733936.1|ensembl:ENSG00000112294(gene)|ensembl:ENST00000357578(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51649|rcsb pdb:2W8N|rcsb pdb:2W8O|rcsb pdb:2W8P|rcsb pdb:2W8Q|rcsb pdb:2W8R|reactome:R-HSA-916853|entrezgene/locuslink:7915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606 rogid:gCoItLXLp6W0Cr45kAu+XwADFAs9606 rigid:cVq029arMhhNdlZFDIfF2CEwrCs false sufficient binding region:111-429 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GN5-2 uniprotkb:X5D778 intact:EBI-9091443 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:q96gn5-2(display_long)|uniprotkb:HR1(gene name synonym)|uniprotkb:JPO2(gene name synonym)|uniprotkb:Protein JPO2(gene name synonym)|uniprotkb:R1(gene name synonym)|uniprotkb:Transcription factor RAM2(gene name synonym)|uniprotkb:Variant B(isoform synonym)|uniprotkb:CDCA7L(gene name)|psi-mi:CDCA7L(display_short) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247000|imex:IM-24135-1353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5278764(isoform-parent)|uniprotkb:Q96GN5-2(isoform-parent)|entrezgene/locuslink:55536(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wcrQtkogtBLIPTSe1iz4xoeshSY9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:kAKA88fkJc/ptK9JGtQ9JDAvtAA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D2C1 uniprotkb:X5D778 intact:EBI-21246980 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21246992|imex:IM-24135-1001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:AMok8VQV7tr9F7jRzEMn/+3UdZ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MT8-3 uniprotkb:A0A087WVE9 intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247136|imex:IM-24135-1003 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:ee+ahpObR54PBFyqMUXlQY08Uqg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P2R3 uniprotkb:A0A087WVE9 intact:EBI-12696312|ensembl:ENSP00000383936|ensembl:ENSP00000430911 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q6p2r3_human(display_long)|uniprotkb:CEP57L1(gene name)|psi-mi:CEP57L1(display_short)|uniprotkb:C6orf182(gene name synonym)|uniprotkb:hCG_34126(orf name) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247128|imex:IM-24135-1193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183137(gene)|ensembl:ENST00000407272(transcript)|ensembl:ENST00000519095(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|interpro:IPR025913|entrezgene/locuslink:285753(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:obdCZ2a9kCFiQU+V3H5cv4B7TgA9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:QMy+rzmpP7r9CsLIIzxocKNdXnY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01850 uniprotkb:A0A087WVE9 intact:EBI-1181367|uniprotkb:Q13977|uniprotkb:A8K8A8|ensembl:ENSP00000268383 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:cdr2_human(display_long)|uniprotkb:Paraneoplastic cerebellar degeneration-associated antigen(gene name synonym)|uniprotkb:Major Yo paraneoplastic antigen(gene name synonym)|uniprotkb:CDR2(gene name)|psi-mi:CDR2(display_short)|uniprotkb:PCD17(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247118|imex:IM-24135-1191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001793.1|ensembl:ENSG00000140743(gene)|ensembl:ENST00000268383(transcript)|interpro:IPR026079|mint:Q01850|refseq:XP_005276559.1|entrezgene/locuslink:1039(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:TYCAl4weno3VU167nI6ARIiWQZY9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:8unid7zh2Smv88UUlXuuJ2F5SsA false sufficient binding region:12-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N5R6 uniprotkb:A0A087WVE9 intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247110|imex:IM-24135-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2021/11/30 rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:BDYhJYm2SLHwDuJUVx/cDuPYUBQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:A0A087WVE9 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247102|imex:IM-24135-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:ZNCozv1JdxMSwnTQcBPvU5HoIC0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43364 intact:EBI-21247090 intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358 - psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym) psi-mi:ar(display_short)|psi-mi:EBI-21247090(display_long) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247092|imex:IM-24135-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity) entrezgene/locuslink:367(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606 rogid:wvdZkJPqNLB1OI88kaK8MSi4FoI9606 rigid:FdX0ymFgcB9NXQMmQejl5nGkNAI false sufficient binding region:111-429 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94972 uniprotkb:X5D778 intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247082|imex:IM-24135-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:vmuRd15l7MQOyJX/gV3uowJ+q+w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:X5D778 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247074|imex:IM-24135-1355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:bWFQcHorejXiBCKiDjwZjAyBK6Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:X5D778 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247066|imex:IM-24135-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:/fWxDh4XFg/v0So+CbT92rGBprI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VU43-2 uniprotkb:X5D778 intact:EBI-9640281|ensembl:ENSP00000316434 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:q5vu43-2(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247058|imex:IM-24135-795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1105124(isoform-parent)|ensembl:ENST00000313431(transcript)|ensembl:ENSG00000178104(gene)|uniprotkb:Q5VU43-2(isoform-parent)|entrezgene/locuslink:9659(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - isoform-comment:Contains a phosphoserine at position 252. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:A1O+nIJfaGaEguWbxsYIwBdmu/s9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:CTW6MkZp7ZkvvlrfKmx0rOjS+qE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13064 uniprotkb:X5D778 intact:EBI-2340269|ensembl:ENSP00000313881 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247050|imex:IM-24135-793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064|entrezgene/locuslink:7681(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:B49nkP71QTZNnL94bsp7vqbWPBU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:X5D778 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247042|imex:IM-24135-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:uGxJBcogcpebYLcrT9rQrtUnatw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9C0F1 uniprotkb:X5D778 intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247034|imex:IM-24135-791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:gDTC64oDhudGdsssC7v+suIHZkA9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:ieyVQrG/eNGY7cfVjXJvmFwo8jE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13422-7 uniprotkb:X5D778 intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247026|imex:IM-24135-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:5/O8drM6TDmL/wgd4PBrh8blyGw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96ED9-2 uniprotkb:X5D778 intact:EBI-10961706|ensembl:ENSP00000264827 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247018|imex:IM-24135-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:tSHiq5NVpX22/m8T6cLeZsVv/eg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:X5D778 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247008|imex:IM-24135-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:YihNqg8gCnBuIRCgyECMm18FaZw false sufficient binding region:13-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WWB3 uniprotkb:A0A087WVE9 intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247161|imex:IM-24135-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:/wTv8g1no9uoAXgvh4ahYynSca8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:A0A087WVE9 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247145|imex:IM-24135-1195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:SU1lFVRrkQAASEwbBTNWeDkmHd0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86UW9 uniprotkb:A0A087WVE9 intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247153|imex:IM-24135-985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:DuCgcLxxA5en15Wt1OjHPVHIXlY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:A0A087WVE9 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247169|imex:IM-24135-1005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:1Cut+syVqPPXRY7OPY36eKAT6jU false sufficient binding region:383-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16665 uniprotkb:A0A087WVE9 intact:EBI-447269|uniprotkb:Q53XP6|uniprotkb:Q96PT9|uniprotkb:Q9UPB1|uniprotkb:C0LZJ3|ensembl:ENSP00000338018 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:hif1a_human(display_long)|uniprotkb:ARNT-interacting protein(gene name synonym)|uniprotkb:Member of PAS protein 1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)|uniprotkb:HIF1A(gene name)|psi-mi:HIF1A(display_short)|uniprotkb:MOP1(gene name synonym)|uniprotkb:BHLHE78(gene name synonym)|uniprotkb:PASD8(gene name synonym)|uniprotkb:PAS domain-containing protein 8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247179|imex:IM-24135-1007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230013.1|refseq:NP_001521.1|refseq:NP_851397.1|ensembl:ENST00000323441|ensembl:ENSP00000323326|ensembl:ENSP00000338018|ensembl:ENST00000539097|ensembl:ENSP00000437955|dip:DIP-29722N|ensembl:ENSG00000100644(gene)|ensembl:ENST00000337138(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q16665|rcsb pdb:1D7G|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1L3E|rcsb pdb:1L8C|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:2ILM|rcsb pdb:3HQR|rcsb pdb:3HQU|rcsb pdb:4AJY|rcsb pdb:4H6J|rcsb pdb:5JWP|rcsb pdb:5L9B|rcsb pdb:5L9V|rcsb pdb:5LA9|rcsb pdb:5LAS|rcsb pdb:6GFX|rcsb pdb:6GMR|rcsb pdb:6YW3|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|reactome:R-HSA-2122947|reactome:R-HSA-400253|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8849473|reactome:R-HSA-8857538|reactome:R-HSA-8951664|entrezgene/locuslink:3091(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:3XRt8HFMCRlxcYR2KfuFSq6gVBg9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:bNAP/AUVNszZVsyETfjTPJyhnGY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43358 uniprotkb:A0A087WVE9 intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247211|imex:IM-24135-803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1|entrezgene/locuslink:4103(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wF193QbpesCr14OlGMQD+BabWvs9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:AzttX68/k+AQthNANvCEjkJdkTA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14770-4 uniprotkb:A0A087WVE9 intact:EBI-8025850|ensembl:ENSP00000341400|intact:MINT-4841606 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:o14770-4(display_long)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:Meis2D(isoform synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short)|uniprotkb:MRG1(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247219|imex:IM-24135-1357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134138(gene)|ensembl:ENST00000338564(transcript)|intact:EBI-2804934(isoform-parent)|uniprotkb:O14770-4(isoform-parent)|entrezgene/locuslink:4212(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:bmX3MQjtyXhYf4495rfBgcY7wys9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:kcAHrcNqjIfshd83hTNm0D6/C5A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TD10 uniprotkb:A0A087WVE9 intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247227|imex:IM-24135-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:nOFJ7W3cbPI1BtyvvKGjQ4SfwJ0 false sufficient binding region:182-442 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:A0A087WVE9 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247237|imex:IM-24135-1361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:8KmRIEmo5VKsnwglLwDu9W4uYfY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y6Q9-5 uniprotkb:A0A087WVE9 intact:EBI-11057583|ensembl:ENSP00000361073 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q9y6q9-5(display_long)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:TRAM1(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:ACTR(gene name synonym)|uniprotkb:AIB1(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247245|imex:IM-24135-1009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124151(gene)|ensembl:ENST00000372004(transcript)|intact:EBI-81196(isoform-parent)|uniprotkb:Q9Y6Q9-5(isoform-parent)|entrezgene/locuslink:8202(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tCrKtF22SQBO+Uk5Ex3dRAg4WiI9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:1TdJOb5nNGU7jYJjbBSOHvHlw+I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99743 uniprotkb:A0A087WVE9 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247253|imex:IM-24135-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:6sHs4yJVuY98+3XYzHKjI7+V1U8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VU43-2 uniprotkb:A0A087WVE9 intact:EBI-9640281|ensembl:ENSP00000316434 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q5vu43-2(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247261|imex:IM-24135-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1105124(isoform-parent)|ensembl:ENST00000313431(transcript)|ensembl:ENSG00000178104(gene)|uniprotkb:Q5VU43-2(isoform-parent)|entrezgene/locuslink:9659(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:Contains a phosphoserine at position 252. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:A1O+nIJfaGaEguWbxsYIwBdmu/s9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:OTYu14vG6SSf7yTY4WX2W44rT0Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:A0A087WVE9 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247269|imex:IM-24135-1011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:d2TJ/Upi0ywJd6iNN5CzF6Ov7cc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYM8 uniprotkb:A0A087WVE9 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247277|imex:IM-24135-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N|entrezgene/locuslink:10616(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:cW49H73oafVH/7RjXrtq11m5tf4 false sufficient binding region:11-510 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:A0A087WVE9 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247287|imex:IM-24135-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:gYgcNGPRjyQUy1n5ks84h8+Ku7o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8HWS3 uniprotkb:A0A087WVE9 intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247295|imex:IM-24135-1013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:yHJrKu0B45hMkI1YGo7TsIa3DIg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UFD9 uniprotkb:A0A087WVE9 intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247303|imex:IM-24135-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:7wsHR/mpizAKTHFjhm40+xwjQyM false sufficient binding region:838-1639 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6NUQ1 uniprotkb:A0A087WVE9 intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247313|imex:IM-24135-1363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:X+bQvFUpmVSP4F0pXaukqr1xCTc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BVG8-5 uniprotkb:A0A087WVE9 intact:EBI-14069005|ensembl:ENSP00000396399|ensembl:ENSP00000454659|ensembl:ENSP00000456239 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q9bvg8-5(display_long)|uniprotkb:KIFC3(gene name)|psi-mi:KIFC3(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247195|imex:IM-24135-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2125614(isoform-parent)|uniprotkb:Q9BVG8-5(isoform-parent)|ensembl:ENSG00000140859(gene)|ensembl:ENST00000421376(transcript)|ensembl:ENST00000465878(transcript)|ensembl:ENST00000562903(transcript)|entrezgene/locuslink:3801(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:0+/OISIWq43SLdciB0TI/JqsEUo9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:COIuAV7XR3t1XcFVxtlgDaxagFk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKT9 uniprotkb:A0A087WVE9 intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247187|imex:IM-24135-801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:sEDs/NxsnzwHXeOJuqdntMGSlbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:A0A087WVE9 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247203|imex:IM-24135-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:yddEpvtHR2l/5WEcZs0dqobN9/M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:A0A087WVE9 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247395|imex:IM-24135-1197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:tgaZQVhkZvJ/iv1y3bmMX8uM4+c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01850 uniprotkb:X5DP31 intact:EBI-1181367|uniprotkb:Q13977|uniprotkb:A8K8A8|ensembl:ENSP00000268383 intact:EBI-21247516 psi-mi:cdr2_human(display_long)|uniprotkb:Paraneoplastic cerebellar degeneration-associated antigen(gene name synonym)|uniprotkb:Major Yo paraneoplastic antigen(gene name synonym)|uniprotkb:CDR2(gene name)|psi-mi:CDR2(display_short)|uniprotkb:PCD17(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247574|imex:IM-24135-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001793.1|ensembl:ENSG00000140743(gene)|ensembl:ENST00000268383(transcript)|interpro:IPR026079|mint:Q01850|refseq:XP_005276559.1|entrezgene/locuslink:1039(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:TYCAl4weno3VU167nI6ARIiWQZY9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:sohLP5Hwr4hklBRMF3PuJ+HTRnc false sufficient binding region:12-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:A0A087WVE9 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247379|imex:IM-24135-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:CCHTbPoxYvile96h6HJeCOBCr9g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75478 uniprotkb:A0A087WVE9 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247371|imex:IM-24135-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:7l4uZKT7/S9U+/dDtOeOTR2/w1s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y6A5 uniprotkb:A0A087WVE9 intact:EBI-2554984|uniprotkb:Q2NKK4|uniprotkb:Q9UMQ1|uniprotkb:Q3KQS5|ensembl:ENSP00000326550|ensembl:ENSP00000498361 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:tacc3_human(display_long)|uniprotkb:ERIC1(gene name synonym)|uniprotkb:ERIC-1(gene name synonym)|uniprotkb:TACC3(gene name)|psi-mi:TACC3(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247363|imex:IM-24135-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006333.1|ensembl:ENSG00000013810(gene)|ensembl:ENST00000313288(transcript)|ensembl:ENST00000651472(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902850"(microtubule cytoskeleton organization involved in mitosis)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|rcsb pdb:5LXN|rcsb pdb:5LXO|rcsb pdb:5ODS|rcsb pdb:5ODT|reactome:R-HSA-9013507|reactome:R-HSA-9604323|refseq:XP_016863142.1|entrezgene/locuslink:10460(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:gMVaNgiXeS4kmmJ3ol+/hn9HwXc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:m7ypxw8COJZxwTGbX9o7UsYfmd4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N0S2 uniprotkb:A0A087WVE9 intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247353|imex:IM-24135-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:wOHiMhd3dl7U136PjPEandqYbAY false sufficient binding region:37-351 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y2D8 uniprotkb:A0A087WVE9 intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247345|imex:IM-24135-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:ZAK7Yq+1gD9I6wYXb1xDDmI0iv0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUZ4 uniprotkb:A0A087WVE9 intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247403|imex:IM-24135-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:rRuhufWCLttBwffAdLcnVISOZr4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:A0A087WVE9 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247411|imex:IM-24135-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:hmkdZmIfV3zDxs1zJ3IFXGfKel8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:A0A087WVE9 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247419|imex:IM-24135-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:fhiAwBp/IN2PoGTcW+wcyWXeDuM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IWZ5 uniprotkb:A0A087WVE9 intact:EBI-5235829|intact:EBI-10172216|uniprotkb:A1L4B6|uniprotkb:A1L4B4|uniprotkb:Q8N832|uniprotkb:Q8NDL3|ensembl:ENSP00000286349 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:tri42_human(display_long)|uniprotkb:TRIM42(gene name)|psi-mi:TRIM42(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247427|imex:IM-24135-809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689829.3|ensembl:ENSG00000155890(gene)|ensembl:ENST00000286349(transcript)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR036116|interpro:IPR042765|entrezgene/locuslink:287015(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:cLHTKcNRr2xZE+yUrqw2xLaPeXY9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:OUGavC2/R/aOgYpyMe97qt2wHxU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11524292 uniprotkb:A0A087WVE9 - intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247435|imex:IM-24135-1019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:7205(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - no-uniprot-update: - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S6W5lkNauGhNejln9bTVoqZjNL49606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:tTrd1oFsen2EL8kMQfEG2jaCm0Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6Y0 uniprotkb:A0A087WVE9 intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247443|imex:IM-24135-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:OQRiU5K+30hyPKF+p/Svz7zJ/UA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N1B4 uniprotkb:A0A087WVE9 intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247451|imex:IM-24135-1365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:RC6nW8lJBsYz9FJoC/NgP34wyV4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYN7-2 uniprotkb:A0A087WVE9 intact:EBI-16435478|ensembl:ENSP00000344308 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q9byn7-2(display_long)|uniprotkb:ZNF341(gene name)|psi-mi:ZNF341(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247459|imex:IM-24135-1021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9089622(isoform-parent)|uniprotkb:Q9BYN7-2(isoform-parent)|ensembl:ENSG00000131061(gene)|ensembl:ENST00000342427(transcript)|entrezgene/locuslink:84905(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:Gene prediction based on EST data. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7vGJ+B6pyJ7Sog6LMmkaucXK7wI9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:a/rvCmDjquEf+cV38JzwxbCUIfY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUZ4 uniprotkb:X5D9H9 intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395 intact:EBI-21247467 psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym) psi-mi:x5d9h9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247482|imex:IM-24135-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606 rogid:5nxEa9UITw6DIFduoQe4KL7W8v89606 rigid:5TeIYCRJ0oVBxUJM2KvsJCawZ/g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUZ4 uniprotkb:X5D7T2 intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395 intact:EBI-21247490 psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym) psi-mi:x5d7t2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247508|imex:IM-24135-1023 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606 rogid:NlqyT5IhG1S2qMN50JrRE0ERns89606 rigid:qnOoQJU42E61lw+Q/dKL/waLNw8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14-3 uniprotkb:X5DP31 intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295 intact:EBI-21247516 psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247534|imex:IM-24135-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:5V2uYv9T96UkLLxtXQOZfbPKJXE false sufficient binding region:674-1097 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D8V5 uniprotkb:X5DP31 intact:EBI-21247544 intact:EBI-21247516 psi-mi:x5d8v5_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247558|imex:IM-24135-1025 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:zcWGe0gHIWD0FamIyAXG3hRd8QQ9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:HcmycQBHiprkQaVPY82id/laWzk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:X5DP31 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-21247516 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247566|imex:IM-24135-811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:/uSWa/n1r1K+gVPoM1SM/pBdiaM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60504 uniprotkb:A0A087WVE9 intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247321|imex:IM-24135-805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|entrezgene/locuslink:10174(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:44p5BHQYcZFNb1aA18VMI8XXZ4I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96R06 uniprotkb:A0A087WVE9 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247329|imex:IM-24135-1015 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:2263QFu7M27uukrmGDg6Nh7N900 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BWW4 uniprotkb:A0A087WVE9 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247337|imex:IM-24135-807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - crc64:DBBB169D4EE10536 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:Zq7lbTZ/SfeI6tbe1EV7IjGg4Jo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13077 uniprotkb:A0A087WVE9 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247387|imex:IM-24135-1017 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:YZtL7vFTysP8eArU0CHxMYaunQo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DP31 intact:EBI-16439278 intact:EBI-21247516 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247610|imex:IM-24135-1199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:n7jdjcJ6SroPwgp7orEOEQu3n0w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:X5DP31 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-21247516 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247584|imex:IM-24135-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:AiMOL5L9LxcY6tho8dXEZWkrr2c false sufficient binding region:383-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:X5DP31 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-21247516 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247618|imex:IM-24135-1201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:Q45yzgLFC7zk63cWKlY2kMbLXEc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:X5DP31 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-21247516 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247602|imex:IM-24135-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:wERQA2Mz+hxTJTxVNW7hzl7UDF8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16665 uniprotkb:X5DP31 intact:EBI-447269|uniprotkb:Q53XP6|uniprotkb:Q96PT9|uniprotkb:Q9UPB1|uniprotkb:C0LZJ3|ensembl:ENSP00000338018 intact:EBI-21247516 psi-mi:hif1a_human(display_long)|uniprotkb:ARNT-interacting protein(gene name synonym)|uniprotkb:Member of PAS protein 1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)|uniprotkb:HIF1A(gene name)|psi-mi:HIF1A(display_short)|uniprotkb:MOP1(gene name synonym)|uniprotkb:BHLHE78(gene name synonym)|uniprotkb:PASD8(gene name synonym)|uniprotkb:PAS domain-containing protein 8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247594|imex:IM-24135-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230013.1|refseq:NP_001521.1|refseq:NP_851397.1|ensembl:ENST00000323441|ensembl:ENSP00000323326|ensembl:ENSP00000338018|ensembl:ENST00000539097|ensembl:ENSP00000437955|dip:DIP-29722N|ensembl:ENSG00000100644(gene)|ensembl:ENST00000337138(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q16665|rcsb pdb:1D7G|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1L3E|rcsb pdb:1L8C|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:2ILM|rcsb pdb:3HQR|rcsb pdb:3HQU|rcsb pdb:4AJY|rcsb pdb:4H6J|rcsb pdb:5JWP|rcsb pdb:5L9B|rcsb pdb:5L9V|rcsb pdb:5LA9|rcsb pdb:5LAS|rcsb pdb:6GFX|rcsb pdb:6GMR|rcsb pdb:6YW3|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|reactome:R-HSA-2122947|reactome:R-HSA-400253|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8849473|reactome:R-HSA-8857538|reactome:R-HSA-8951664|entrezgene/locuslink:3091(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:3XRt8HFMCRlxcYR2KfuFSq6gVBg9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:xS2fgwYnGQO9rVoCej5wG7aJ6Ms false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VU43-2 uniprotkb:X5DP31 intact:EBI-9640281|ensembl:ENSP00000316434 intact:EBI-21247516 psi-mi:q5vu43-2(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247627|imex:IM-24135-1203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1105124(isoform-parent)|ensembl:ENST00000313431(transcript)|ensembl:ENSG00000178104(gene)|uniprotkb:Q5VU43-2(isoform-parent)|entrezgene/locuslink:9659(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - isoform-comment:Contains a phosphoserine at position 252. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:A1O+nIJfaGaEguWbxsYIwBdmu/s9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:8KLNidvr5PhDJ/gTVYN6OKhqewM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:P01185 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-6858021|ensembl:ENSP00000369647|uniprotkb:A0AV35|uniprotkb:O14935 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:neu2_human(display_long)|uniprotkb:AVP(gene name)|psi-mi:AVP(display_short)|uniprotkb:ARVP(gene name synonym)|uniprotkb:VP(gene name synonym)|uniprotkb:AVP-NPII(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247757|imex:IM-24135-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) refseq:XP_011527569.1|ensembl:ENSG00000101200(gene)|ensembl:ENST00000380293(transcript)|go:"GO:0002125"(maternal aggressive behavior)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005184"(neuropeptide hormone activity)|go:"GO:0005185"(neurohypophyseal hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006833"(water transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007621"(negative regulation of female receptivity)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031894"(V1A vasopressin receptor binding)|go:"GO:0031895"(V1B vasopressin receptor binding)|go:"GO:0032849"(positive regulation of cellular pH reduction)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033574"(response to testosterone)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0035813"(regulation of renal sodium excretion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0042310"(vasoconstriction)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR000981(Neurohypophysial hormone)|interpro:IPR022423|interpro:IPR036387|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042711"(maternal behavior)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|rcsb pdb:7KH0|reactome:R-HSA-1368108|reactome:R-HSA-388479|go:"GO:0043084"(penile erection)|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-432040|reactome:R-HSA-5619099|reactome:R-HSA-879518|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9036092|reactome:R-HSA-9660821|refseq:NP_000481.2|entrezgene/locuslink:551(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:gJEuKmkzkofslMInl8lIcRtZlXE9606 rigid:WXtKKKHwKLJNo0IOLNWBsYgFnBM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:X5DP31 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-21247516 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247635|imex:IM-24135-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:DSF9jEloF+At+z/ej/PCuky2Ax0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94972 uniprotkb:X5DP31 intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6 intact:EBI-21247516 psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247741|imex:IM-24135-1371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:m+CZn+KukWr2QZUxCCu4q2rtML0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:X5DP31 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-21247516 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247733|imex:IM-24135-1369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:crSMt3dV7QlrjMgmtd05KXbr/iM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:X5DP31 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-21247516 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247725|imex:IM-24135-819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:GnKBN6kJ67m+GQk3gtKiIPXMmMk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUZ4 uniprotkb:X5DP31 intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395 intact:EBI-21247516 psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247717|imex:IM-24135-1207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:dyA5S+nXHgFeTBOWDZrX0UQUPlE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:X5DP31 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-21247516 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247709|imex:IM-24135-1205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:64MAVt3vjCDzDIuiJ5vAnkdQ8U8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13077 uniprotkb:X5DP31 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-21247516 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247701|imex:IM-24135-817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:gnD7R+y/MYRZzlkiuUeBGaViUeg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:X5DP31 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-21247516 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247693|imex:IM-24135-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:7yo7+qy30pSZap0TUlbpGrMuj/M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N0S2 uniprotkb:X5DP31 intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3 intact:EBI-21247516 psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247683|imex:IM-24135-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:RsFnWPJwD7lYf5O51a27qb/NCxM false sufficient binding region:37-351 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y2D8 uniprotkb:X5DP31 intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279 intact:EBI-21247516 psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247675|imex:IM-24135-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:JYc/eiZzJ61EC/nI9FM8pGsDdbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96R06 uniprotkb:X5DP31 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 intact:EBI-21247516 psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247667|imex:IM-24135-815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:8gjAO9O6Wra0sdH8h64GJJfpeCc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6NUQ1 uniprotkb:X5DP31 intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700 intact:EBI-21247516 psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247659|imex:IM-24135-1367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N|entrezgene/locuslink:60561(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:aI83E7K493xad2OM4NNI+LpGZWk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8HWS3 uniprotkb:X5DP31 intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208 intact:EBI-21247516 psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247651|imex:IM-24135-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:7MhTPJPmyzLj3Z1bZOgbPscNYBA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5DP31 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21247516 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247643|imex:IM-24135-813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:7RJA+GglbZxVmIyCKZR4GKVXkkI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11524292 uniprotkb:X5DP31 - intact:EBI-21247516 psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247749|imex:IM-24135-821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:7205(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - no-uniprot-update: - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S6W5lkNauGhNejln9bTVoqZjNL49606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:KECwQ6CxPrPTiB30lzkS9eZPAhU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5D7U3 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21247834 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247875|imex:IM-24135-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:vmTNb6ixkHuePfgnKW5M1nxCvXw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D09 uniprotkb:X5D7U3 intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0 intact:EBI-21247834 psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247867|imex:IM-24135-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:hxGvvhErCyXc9xf/b55/HeibaJw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TAP6 uniprotkb:X5D7U3 intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1 intact:EBI-21247834 psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247859|imex:IM-24135-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:V4sxbensTfEpK93HZwSPI1EeXq8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7U3 uniprotkb:X5D7U3 intact:EBI-21247834 intact:EBI-21247834 psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247851|imex:IM-24135-825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:rXhaxYLE4WQfVNR1C1GyUHjrNmA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7L4P6 uniprotkb:X5D7U3 intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085 intact:EBI-21247834 psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247843|imex:IM-24135-1029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:CP2WlBxpUIH+0vy3Im6BsK70Pkc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D7A4 intact:EBI-21247765 intact:EBI-21247765 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247778|imex:IM-24135-1373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rigid:0Ds3WWUYAa/8yrq97MFphJMWIts false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96D09 uniprotkb:X5D2C1 intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0 intact:EBI-21246980 psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247818|imex:IM-24135-1211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:4STlZdAk+z+Yz/G+6eot74Ig7s4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5D2C1 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21246980 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247810|imex:IM-24135-1375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:AC7I03x5GlN94ShNHGA2+NVxerc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRI5-2 uniprotkb:X5D2C1 intact:EBI-11988027|ensembl:ENSP00000355597 intact:EBI-21246980 psi-mi:q9nri5-2(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)|uniprotkb:LV(isoform synonym) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247802|imex:IM-24135-1209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-529989(isoform-parent)|ensembl:ENSG00000162946(gene)|ensembl:ENST00000366637(transcript)|uniprotkb:Q9NRI5-2(isoform-parent)|entrezgene/locuslink:27185(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - isoform-comment:Non-canonical donor and acceptor splice sites for the last 2 exons. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XO2u/5sOZAkkn12A+INm5SA4jUY9606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:V5L7pW3g16Pg7WTMlOxb4DjbFfI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D2C1 uniprotkb:X5D2C1 intact:EBI-21246980 intact:EBI-21246980 psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247794|imex:IM-24135-1027 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:lnEIsl0dUkTUnrGJ0yTGZJXZ7MA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5D7A4 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21247765 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247786|imex:IM-24135-823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rigid:V8orN2LXwlyfrYc+CTVVM8FhgSc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5D2C1 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21246980 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247826|imex:IM-24135-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:15GzCufQURUTmfyLJz/M2mwjFBc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:Q14194 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248179|imex:IM-24135-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rigid:oM+j0aHO+dgbwDWzuZ0Bs9pAO/4 false sufficient binding region:383-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15884-3 uniprotkb:X5D7U3 intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670 intact:EBI-21247834 psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247883|imex:IM-24135-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:t44WZQr8n804PYgNi3jM79LzYNM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16555 uniprotkb:Q14194 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248163|imex:IM-24135-833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|entrezgene/locuslink:1808(identity) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rigid:FnMFn3xcsPpOC8kj+nR8C3siNSk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14194 uniprotkb:Q14194 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248155|imex:IM-24135-1035 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rigid:pGRqhbTnkETW1ZgoYcW7gFyczis false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16555 uniprotkb:X5DQV1 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-21248134 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:x5dqv1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248147|imex:IM-24135-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|entrezgene/locuslink:1808(identity) go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR030624|interpro:IPR011778(D-hydantoinase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|entrezgene/locuslink:1400(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:RGQRCGrECTyoeynXn3RIIA+R6q09606 rigid:0lDOAsK5Nf2mul14kDezGnaAmMQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14194-2 uniprotkb:Q14194-2 intact:EBI-21248119 intact:EBI-21248119 psi-mi:q141942(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:ULIP3(gene name synonym) psi-mi:q141942(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:ULIP3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248126|imex:IM-24135-1219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14194-2(isoform-parent)|entrezgene/locuslink:1400(identity) uniprotkb:Q14194-2(isoform-parent)|entrezgene/locuslink:1400(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wLmx63akI7DW55pH58Se1CqI0Yc9606 rogid:wLmx63akI7DW55pH58Se1CqI0Yc9606 rigid:jFnhQly/lA5Ve2vXLlCmYzm6Ss4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96DZ9-2 uniprotkb:O14810 intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215 intact:EBI-2691813|uniprotkb:B2R4R5|uniprotkb:A6NI80|uniprotkb:D3DVN3|uniprotkb:F1T0G1|ensembl:ENSP00000305613 psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym) psi-mi:cplx1_human(display_long)|uniprotkb:Complexin I(gene name synonym)|uniprotkb:Synaphin-2(gene name synonym)|uniprotkb:CPLX1(gene name)|psi-mi:CPLX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248111|imex:IM-24135-831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity) refseq:NP_006642.1|ensembl:ENSG00000168993(gene)|ensembl:ENST00000304062(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030073"(insulin secretion)|go:"GO:0030425"(dendrite)|go:"GO:0031201"(SNARE complex)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0044305"(calyx of Held)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070554"(synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR008849(Synaphin)|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-888590|dip:DIP-56109N|entrezgene/locuslink:10815(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606 rogid:fLmOGVm1+wD17+eGvRa7ZRErvMk9606 rigid:jmpTFmE0Adp7UxEVtpny8WJRHoI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6RW13-2 uniprotkb:O14810 intact:EBI-11522760|ensembl:ENSP00000365816 intact:EBI-2691813|uniprotkb:B2R4R5|uniprotkb:A6NI80|uniprotkb:D3DVN3|uniprotkb:F1T0G1|ensembl:ENSP00000305613 psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym) psi-mi:cplx1_human(display_long)|uniprotkb:Complexin I(gene name synonym)|uniprotkb:Synaphin-2(gene name synonym)|uniprotkb:CPLX1(gene name)|psi-mi:CPLX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248103|imex:IM-24135-829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity) refseq:NP_006642.1|ensembl:ENSG00000168993(gene)|ensembl:ENST00000304062(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030073"(insulin secretion)|go:"GO:0030425"(dendrite)|go:"GO:0031201"(SNARE complex)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0044305"(calyx of Held)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070554"(synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR008849(Synaphin)|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-888590|dip:DIP-56109N|entrezgene/locuslink:10815(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:PNzVis/8puQZBJ562gCqZKc078s9606 rogid:fLmOGVm1+wD17+eGvRa7ZRErvMk9606 rigid:NxKN9+5ap6OunQOPLlPcmAmMVVM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D2E8 intact:EBI-16439278 intact:EBI-21248087 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d2e8_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248095|imex:IM-24135-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0016021"(integral component of membrane)|interpro:IPR042192|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|entrezgene/locuslink:26047(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:CliHoj76cgObJy4OWKiEjXBUxX49606 rigid:PXDBdOobdQV92AoypJpZSrGWVsc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DQU5 intact:EBI-16439278 intact:EBI-21248068 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dqu5_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248079|imex:IM-24135-1217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0016021"(integral component of membrane)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR029831|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|entrezgene/locuslink:26047(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid://4u1+czLI8/RyWmW+Wl4YFEYE89606 rigid:1C18OiwXJNkulzoPyhwV5leDzMY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D7C2 intact:EBI-16439278 intact:EBI-21248049 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d7c2_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248060|imex:IM-24135-1377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0016021"(integral component of membrane)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR029831|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|entrezgene/locuslink:26047(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:/uRd3fXicPqqGY8YBvRJKFaBNdQ9606 rigid:Th6SoR2jBXAPxM/Q9mqgfoVfW0I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D9M6 intact:EBI-16439278 intact:EBI-21248035 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d9m6_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248041|imex:IM-24135-1215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR029831|entrezgene/locuslink:26047(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:Uobiekvx9dGG3td3Ezv0LV17XwE9606 rigid:3rJx9QpXSBULp3pguqh+TdeWpNA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DNH4 intact:EBI-16439278 intact:EBI-21248011 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dnh4_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248027|imex:IM-24135-827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR029831|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR036056|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008979(Galactose-binding like)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|entrezgene/locuslink:26047(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:r7YZkue/umRM3ijPsh5j1k117Dg9606 rigid:vg7t6eX9SxOENYVbOr5Efqsq8cw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q9UHC6 intact:EBI-16439278 intact:EBI-310892|uniprotkb:Q14DG2|uniprotkb:Q52LV1|uniprotkb:Q5H9Q7|uniprotkb:Q9UQ12|uniprotkb:D3DWG2|ensembl:ENSP00000354778 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:cntp2_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short)|uniprotkb:CASPR2(gene name synonym)|uniprotkb:KIAA0868(gene name synonym)|uniprotkb:Cell recognition molecule Caspr2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248003|imex:IM-24135-1033 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_054860.1|ensembl:ENSG00000174469(gene)|ensembl:ENST00000361727(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008038"(neuron recognition)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019899"(enzyme binding)|go:"GO:0021756"(striatum development)|go:"GO:0021761"(limbic system development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0030673"(axolemma)|go:"GO:0031175"(neuron projection development)|go:"GO:0033010"(paranodal junction)|go:"GO:0035176"(social behavior)|go:"GO:0042297"(vocal learning)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045163"(clustering of voltage-gated potassium channels)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0071625"(vocalization behavior)|go:"GO:1903598"(positive regulation of gap junction assembly)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR029831|interpro:IPR036056|rcsb pdb:5Y4M|go:"GO:0044224"(juxtaparanode region of axon)|entrezgene/locuslink:26047(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:lxU5rHVgSUp+Mf/i+BQYKZZqn+Q9606 rigid:EzBksS6ZNMJ3vV8QrzO8FrxviIQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q9ULB4 intact:EBI-16439278 intact:EBI-21247960|intact:EBI-28988117|ensembl:ENSP00000231021|uniprotkb:Q3B7I5 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:cadh9_human(display_long)|uniprotkb:CDH9(gene name)|psi-mi:CDH9(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247995|imex:IM-24135-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0099560"(synaptic membrane adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|reactome:R-HSA-418990|ensembl:ENSG00000113100(gene)|ensembl:ENST00000231021(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|ensembl:ENSP00000231021|refseq:NP_057363.3|entrezgene/locuslink:1007(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:eKpP9eU+toZlqFf7OmOKHtJXRvk9606 rigid:/oOrenV2reeDVTrBvJWh8DRvBxM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14923 uniprotkb:X5DQT8 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 intact:EBI-21247941 psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:x5dqt8_human(display_long)|uniprotkb:CDH10(gene name)|psi-mi:CDH10(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247952|imex:IM-24135-1031 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|entrezgene/locuslink:3728(identity) go:"GO:0005509"(calcium ion binding)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0005886"(plasma membrane)|interpro:IPR039808|interpro:IPR015919(Cadherin-like)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR027397|interpro:IPR002126(Cadherin)|entrezgene/locuslink:1008(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 rogid:Tvizzkzw7almwFAHJVQK6uk0now9606 rigid:71fPm5t/eS/q/gmJUD9hDT2nLw8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DNE0 uniprotkb:Q86UW7-2 intact:EBI-21247923 intact:EBI-21247915 psi-mi:x5dne0_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:q86uw72(display_long)|uniprotkb:CADPS2(gene name)|psi-mi:CADPS2(display_short)|uniprotkb:CAPS2(gene name synonym)|uniprotkb:KIAA1591(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247933|imex:IM-24135-1213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035515|interpro:IPR040325|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) uniprotkb:Q86UW7-2(isoform-parent)|entrezgene/locuslink:93664(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NAAtZSEJ78WbTtGKgy+Xs1sZGBE9606 rogid:m5P3sCgHLl4e1DrUwpYtBjote809606 rigid:LCZVMuyeEWRfo0nNT0lKqvOyWf4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3S9 uniprotkb:Q8N4G4 intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929 intact:EBI-10265475|ensembl:ENSP00000435280 psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym) psi-mi:q8n4g4_human(display_long)|uniprotkb:CA6(gene name)|psi-mi:CA6(display_short)|uniprotkb:Carbonic anhydrase 6(gene name synonym)|uniprotkb:Carbonic anhydrase VI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247907|imex:IM-24135-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity) ensembl:ENSG00000131686(gene)|ensembl:ENST00000480186(transcript)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018428|interpro:IPR023561|interpro:IPR036398|entrezgene/locuslink:765(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606 rogid:XV5x1pysikkkYtr1e2tPeyNMq4A9606 rigid:ZTUVAiAsRAkEHOA+ieJrZ6g3ZUw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IZU0 uniprotkb:Q14CZ0 intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495 intact:EBI-10234807|ensembl:ENSP00000331720 psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short) psi-mi:cp072_human(display_long)|uniprotkb:C16orf72(gene name)|psi-mi:C16orf72(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247899|imex:IM-24135-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity) refseq:NP_054836.2|ensembl:ENSG00000182831(gene)|ensembl:ENST00000327827(transcript)|interpro:IPR029196|interpro:IPR040308|entrezgene/locuslink:29035(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606 rogid:jq7clul44ylxWe0XatjrenH+wZI9606 rigid:STxmOZ4K0OvcT66doBZsPmssON8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3Q8 uniprotkb:X5D7U3 intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9 intact:EBI-21247834 psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21247891|imex:IM-24135-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:bJ5trkKjqtB8TVczg/o8nPOPXnQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96B26 uniprotkb:Q14194 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248171|imex:IM-24135-1037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N|entrezgene/locuslink:11340(identity) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y/cReHiPMubzNruyETohBjbRick9606 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rigid:4tejUf2nsgsjJU1s9mFuz5OywAk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q76N32-2 uniprotkb:Q13363-2 intact:EBI-11975967|ensembl:ENSP00000260569 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q76n32-2(display_long)|uniprotkb:CEP68(gene name)|psi-mi:CEP68(display_short)|uniprotkb:KIAA0582(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248371|imex:IM-24135-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9051024(isoform-parent)|uniprotkb:Q76N32-2(isoform-parent)|ensembl:ENSG00000011523(gene)|ensembl:ENST00000260569(transcript)|entrezgene/locuslink:23177(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:UekWHePDhMzf5AhJOlyQUoYY/f89606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:HXggdsKIfcyVO2BqIXe19K2B7oY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NA82 uniprotkb:Q13363 intact:EBI-2341554|uniprotkb:D3DU09|uniprotkb:Q8N7Z7|uniprotkb:Q8IYS7|ensembl:ENSP00000311496|ensembl:ENSP00000416177 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:marha_human(display_long)|uniprotkb:MARCHF10(gene name)|psi-mi:MARCHF10(display_short)|uniprotkb:MARCH10(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 10(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein X(gene name synonym)|uniprotkb:RING finger protein 190(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF10(gene name synonym)|uniprotkb:RNF190(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248189|imex:IM-24135-835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094345.1|refseq:NP_689811.2|refseq:NP_001275708.1|refseq:NP_001275709.1|ensembl:ENSG00000173838(gene)|ensembl:ENST00000311269(transcript)|ensembl:ENST00000456609(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042583|entrezgene/locuslink:162333(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:xYNhVYIVxXneNrLbdaSO0uTK9l89606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:NQXV01snRRIXLAbxf75ccXAKJX4 false sufficient binding region:1-657 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MY1-2 uniprotkb:Q13363-2 intact:EBI-21248199 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q96my12(display_long)|uniprotkb:NOL4L(gene name)|psi-mi:NOL4L(display_short)|uniprotkb:C20orf112(gene name synonym)|uniprotkb:C20orf113(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248353|imex:IM-24135-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q96MY1-2(isoform-parent)|entrezgene/locuslink:140688(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:xAoXY5RzAwyK8aJvRhSgidkx7SY9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:uFY2t9tVJ3fuaa9yHqm5P1Wdp3k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NA82 uniprotkb:Q13363-2 intact:EBI-2341554|uniprotkb:D3DU09|uniprotkb:Q8N7Z7|uniprotkb:Q8IYS7|ensembl:ENSP00000311496|ensembl:ENSP00000416177 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:marha_human(display_long)|uniprotkb:MARCHF10(gene name)|psi-mi:MARCHF10(display_short)|uniprotkb:MARCH10(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 10(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein X(gene name synonym)|uniprotkb:RING finger protein 190(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF10(gene name synonym)|uniprotkb:RNF190(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248343|imex:IM-24135-1225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094345.1|refseq:NP_689811.2|refseq:NP_001275708.1|refseq:NP_001275709.1|ensembl:ENSG00000173838(gene)|ensembl:ENST00000311269(transcript)|ensembl:ENST00000456609(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042583|entrezgene/locuslink:162333(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:xYNhVYIVxXneNrLbdaSO0uTK9l89606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:k6LSB4CqoBE55Vpjm7PHc2gEWhI false sufficient binding region:1-657 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99592 uniprotkb:Q13363 intact:EBI-3232046|uniprotkb:Q9UD99|uniprotkb:Q5VU40|uniprotkb:Q13397|uniprotkb:A8K5U3|uniprotkb:Q8N463|ensembl:ENSP00000481278 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:zbt18_human(display_long)|uniprotkb:ZBTB18(gene name)|psi-mi:ZBTB18(display_short)|uniprotkb:58 kDa repressor protein(gene name synonym)|uniprotkb:RP58(gene name synonym)|uniprotkb:TAZ1(gene name synonym)|uniprotkb:Transcriptional repressor RP58(gene name synonym)|uniprotkb:Translin-associated zinc finger protein 1(gene name synonym)|uniprotkb:ZNF238(gene name synonym)|uniprotkb:Zinc finger protein 238(gene name synonym)|uniprotkb:Zinc finger protein C2H2-171(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248335|imex:IM-24135-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006343.2|refseq:NP_991331.1|refseq:NP_001265125.1|refseq:XP_005273063.1|refseq:XP_016855549.1|ensembl:ENSG00000179456(gene)|ensembl:ENST00000622512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:10472(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:b3uv5xKwJdwq0lxg0znSvWdcBN89606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:blgBvKODcLxhbfE0LcDSYaa4E34 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y5P3 uniprotkb:Q13363 intact:EBI-746228|uniprotkb:Q8N6X7|uniprotkb:B1B1K2|ensembl:ENSP00000333456|ensembl:ENSP00000353106|ensembl:ENSP00000401323|ensembl:ENSP00000444210|uniprotkb:B4DQM9|uniprotkb:E7EMN4 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:rai2_human(display_long)|uniprotkb:RAI2(gene name)|psi-mi:RAI2(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248327|imex:IM-24135-1223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001166214.1|refseq:XP_011543741.1|refseq:XP_011543742.1|refseq:XP_011543743.1|ensembl:ENSG00000131831(gene)|ensembl:ENST00000331511(transcript)|ensembl:ENST00000360011(transcript)|ensembl:ENST00000451717(transcript)|ensembl:ENST00000545871(transcript)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR026092|mint:Q9Y5P3|refseq:NP_001166203.1|refseq:XP_006724522.1|refseq:XP_006724523.1|refseq:NP_001166210.1|refseq:NP_068557.3|entrezgene/locuslink:10742(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:cQ4QQAp6lbQjIvn9xzXPRfUBEzo9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:Swl0T2PJpijeWtedRqi6qb/6Ym8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75928-2 uniprotkb:Q13363 intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248319|imex:IM-24135-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562." - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:IX1UR5HNbBmG0OfNBmBKRI0Dl4k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48552 uniprotkb:Q13363 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248311|imex:IM-24135-1039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N|entrezgene/locuslink:8204(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:9VzXmk11jyy04azTmFuNvMUuPus false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N3X6-3 uniprotkb:Q13363 intact:EBI-12111580|ensembl:ENSP00000317566 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:q8n3x6-3(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248303|imex:IM-24135-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178177(gene)|ensembl:ENST00000326877(transcript)|intact:EBI-7138654(isoform-parent)|uniprotkb:Q8N3X6-3(isoform-parent)|entrezgene/locuslink:254251(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:H86DkZPRtqCS359V/1kzwhYb8vw9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:yQ7Y2aDyODMNbCZbbtO400imkPE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96JN0-2 uniprotkb:Q13363 intact:EBI-10961483|ensembl:ENSP00000443431 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:q96jn0-2(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym)|uniprotkb:C10orf12(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248295|imex:IM-24135-1221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000540664(transcript)|intact:EBI-746045(isoform-parent)|uniprotkb:Q96JN0-2(isoform-parent)|entrezgene/locuslink:84458(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:sX7e6f5T+/jFqvk+QUefJSGgzfE9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:jhHiRpM1r5IVBvrGEq/VsUsGiMc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P57682 uniprotkb:Q13363 intact:EBI-8472267|uniprotkb:Q6PIR1|uniprotkb:Q86TN0|intact:MINT-4786517|uniprotkb:Q9P2X6|ensembl:ENSP00000261438 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:klf3_human(display_long)|uniprotkb:KLF3(gene name)|psi-mi:KLF3(display_short)|uniprotkb:BKLF(gene name synonym)|uniprotkb:Basic krueppel-like factor(gene name synonym)|uniprotkb:CACCC-box-binding protein BKLF(gene name synonym)|uniprotkb:TEF-2(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248287|imex:IM-24135-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057615.3|ensembl:ENSG00000109787(gene)|ensembl:ENST00000261438(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0046872"(metal ion binding)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P57682|entrezgene/locuslink:51274(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - comment:mint|comment:homomint|function:Binds to the CACCC box. May play a role in hematopoiesis - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:iu5f7gyHncp/HoKDVBWll3+ubIA9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:QUYnFNFlGwtN1Trt93UY1pQ0LUE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y4X4 uniprotkb:Q13363 intact:EBI-750750|uniprotkb:Q5VZM7|uniprotkb:Q9UHZ0|uniprotkb:A8K5T2|uniprotkb:L0R3J4|ensembl:ENSP00000366897 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:klf12_human(display_long)|uniprotkb:Transcriptional repressor AP-2rep(gene name synonym)|uniprotkb:KLF12(gene name)|psi-mi:KLF12(display_short)|uniprotkb:AP2REP(gene name synonym)|uniprotkb:HSPC122(orf name) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248279|imex:IM-24135-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009180.3|refseq:XP_011533211.1|refseq:XP_005266308.1|ensembl:ENSP00000366897|ensembl:ENSG00000118922(gene)|ensembl:ENST00000377669(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR030447|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:11278(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JnMHkmGUuZLVFUAZN/f10hHBs/w9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:0oIBx3DV/53s3QkRyInK8TEkCuw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKS7-2 uniprotkb:Q13363 intact:EBI-11536241|ensembl:ENSP00000363439 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:q9uks7-2(display_long)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Helios 1v(isoform synonym)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248271|imex:IM-24135-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3893057(isoform-parent)|ensembl:ENSG00000030419(gene)|ensembl:ENST00000374319(transcript)|uniprotkb:Q9UKS7-2(isoform-parent)|entrezgene/locuslink:22807(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 95." - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:BPYW+3VwNBn9+7Qbh63ii8np0F09606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:42virMHdTse3UIv/nDGms7zbc8E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13422-7 uniprotkb:Q13363 intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248263|imex:IM-24135-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:x3MefAEZo6QPS+W14rhNDaLHLZw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IVP5 uniprotkb:Q13363 intact:EBI-3059266|ensembl:ENSP00000367284 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:fund1_human(display_long)|uniprotkb:FUNDC1(gene name)|psi-mi:FUNDC1(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248255|imex:IM-24135-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000069509(gene)|ensembl:ENST00000378045(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR007014(FUN14)|rcsb pdb:2N9X|rcsb pdb:5GMV|reactome:R-HSA-8934903|refseq:NP_776155.1|entrezgene/locuslink:139341(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ePb5LilgvHruy4JTvgfP43kWUao9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:lIfRtyKqjGlwX3b/jCnXH6NGik8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N3X6-3 uniprotkb:Q13363-2 intact:EBI-12111580|ensembl:ENSP00000317566 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q8n3x6-3(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248453|imex:IM-24135-837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178177(gene)|ensembl:ENST00000326877(transcript)|intact:EBI-7138654(isoform-parent)|uniprotkb:Q8N3X6-3(isoform-parent)|entrezgene/locuslink:254251(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:H86DkZPRtqCS359V/1kzwhYb8vw9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:aF4GAVr++CIsgDXI4+jBHPZNyHE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96JN0-2 uniprotkb:Q13363-2 intact:EBI-10961483|ensembl:ENSP00000443431 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q96jn0-2(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym)|uniprotkb:C10orf12(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248445|imex:IM-24135-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000540664(transcript)|intact:EBI-746045(isoform-parent)|uniprotkb:Q96JN0-2(isoform-parent)|entrezgene/locuslink:84458(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:sX7e6f5T+/jFqvk+QUefJSGgzfE9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:eAZpz/L8lD6OfJN13Ft7qMgMpek false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P57682 uniprotkb:Q13363-2 intact:EBI-8472267|uniprotkb:Q6PIR1|uniprotkb:Q86TN0|intact:MINT-4786517|uniprotkb:Q9P2X6|ensembl:ENSP00000261438 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:klf3_human(display_long)|uniprotkb:KLF3(gene name)|psi-mi:KLF3(display_short)|uniprotkb:BKLF(gene name synonym)|uniprotkb:Basic krueppel-like factor(gene name synonym)|uniprotkb:CACCC-box-binding protein BKLF(gene name synonym)|uniprotkb:TEF-2(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248437|imex:IM-24135-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057615.3|ensembl:ENSG00000109787(gene)|ensembl:ENST00000261438(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0046872"(metal ion binding)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P57682|entrezgene/locuslink:51274(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - comment:mint|comment:homomint|function:Binds to the CACCC box. May play a role in hematopoiesis isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:iu5f7gyHncp/HoKDVBWll3+ubIA9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:7LqvByZuRvUW5nekf5NWo9w9TxA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y4X4 uniprotkb:Q13363-2 intact:EBI-750750|uniprotkb:Q5VZM7|uniprotkb:Q9UHZ0|uniprotkb:A8K5T2|uniprotkb:L0R3J4|ensembl:ENSP00000366897 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:klf12_human(display_long)|uniprotkb:Transcriptional repressor AP-2rep(gene name synonym)|uniprotkb:KLF12(gene name)|psi-mi:KLF12(display_short)|uniprotkb:AP2REP(gene name synonym)|uniprotkb:HSPC122(orf name) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248429|imex:IM-24135-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009180.3|refseq:XP_011533211.1|refseq:XP_005266308.1|ensembl:ENSP00000366897|ensembl:ENSG00000118922(gene)|ensembl:ENST00000377669(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR030447|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:11278(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JnMHkmGUuZLVFUAZN/f10hHBs/w9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:JNU2vEAYmy5nVbU92t6h5BXmz7c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKS7-2 uniprotkb:Q13363-2 intact:EBI-11536241|ensembl:ENSP00000363439 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q9uks7-2(display_long)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Helios 1v(isoform synonym)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248421|imex:IM-24135-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3893057(isoform-parent)|ensembl:ENSG00000030419(gene)|ensembl:ENST00000374319(transcript)|uniprotkb:Q9UKS7-2(isoform-parent)|entrezgene/locuslink:22807(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 95." isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:BPYW+3VwNBn9+7Qbh63ii8np0F09606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:gfNtxSRxDjUMcQP+gwRqFswEsHM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13422-7 uniprotkb:Q13363-2 intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248413|imex:IM-24135-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:Zsk7t1+2AKAzvDOpYt1nkO4ZrBo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IVP5 uniprotkb:Q13363-2 intact:EBI-3059266|ensembl:ENSP00000367284 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:fund1_human(display_long)|uniprotkb:FUNDC1(gene name)|psi-mi:FUNDC1(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248405|imex:IM-24135-1227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000069509(gene)|ensembl:ENST00000378045(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR007014(FUN14)|rcsb pdb:2N9X|rcsb pdb:5GMV|reactome:R-HSA-8934903|refseq:NP_776155.1|entrezgene/locuslink:139341(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ePb5LilgvHruy4JTvgfP43kWUao9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:LHp2LnMAy2Z5xIGzZOeKFLsI8iA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15409 uniprotkb:Q13363-2 intact:EBI-983612|uniprotkb:A0AUV6|uniprotkb:A4D0U8|uniprotkb:Q6ZND1|uniprotkb:Q75MJ3|uniprotkb:Q8IZE0|uniprotkb:Q8N0W2|uniprotkb:Q8N6B7|uniprotkb:Q8N6B8|uniprotkb:Q8NFQ1|uniprotkb:Q8NFQ2|uniprotkb:Q8NFQ3|uniprotkb:Q8NFQ4|uniprotkb:Q8TD74|ensembl:ENSP00000265436|ensembl:ENSP00000377132|uniprotkb:A6NNW4|uniprotkb:B4DLD9 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:foxp2_human(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248395|imex:IM-24135-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128573(gene)|ensembl:ENST00000350908(transcript)|ensembl:ENST00000393494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021757"(caudate nucleus development)|go:"GO:0021758"(putamen development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0098582"(innate vocalization behavior)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:O15409|rcsb pdb:2A07|rcsb pdb:2AS5|go:"GO:0046872"(metal ion binding)|refseq:NP_001166237.1|refseq:NP_001166238.1|refseq:NP_055306.1|refseq:NP_683696.2|refseq:NP_683697.2|refseq:NP_683698.2|dip:DIP-29004N|refseq:XP_016868290.1|entrezgene/locuslink:93986(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XRN9auLs2qtK6W3mjHJHAQPbO9s9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:XcZ61k6QcSP4d54fhDlyEE7fl/E false sufficient binding region:93-715 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P56545-3 uniprotkb:Q13363-2 intact:EBI-10171902|ensembl:ENSP00000357816 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:p56545-3(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248387|imex:IM-24135-1043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175029(gene)|ensembl:ENST00000334808(transcript)|uniprotkb:P56545-3(isoform-parent)|intact:EBI-741533(isoform-parent)|entrezgene/locuslink:1488(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:G2s/fGS3tbCbbh7Jc3m2ugkjI0k9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:+b4I0Tyb7wu29h5TPIV45FiZP48 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:Q13363-2 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248379|imex:IM-24135-1041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:/lCYyt7RKDZpo5fZkPo0nilnZZM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15409-4 uniprotkb:Q13363 intact:EBI-21248240|ensembl:ENSP00000386200 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:o15409-4(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248247|imex:IM-24135-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000408937(transcript)|ensembl:ENSG00000128573(gene)|intact:EBI-983612(isoform-parent)|uniprotkb:O15409-4(isoform-parent)|entrezgene/locuslink:93986(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:59yfQZeiieqvQfd3qY7StG6aMSo9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:D7nEQm40nTLflJ/Q3aMVYrkMLd0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P56545-3 uniprotkb:Q13363 intact:EBI-10171902|ensembl:ENSP00000357816 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:p56545-3(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248232|imex:IM-24135-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175029(gene)|ensembl:ENST00000334808(transcript)|uniprotkb:P56545-3(isoform-parent)|intact:EBI-741533(isoform-parent)|entrezgene/locuslink:1488(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:G2s/fGS3tbCbbh7Jc3m2ugkjI0k9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:u6AdijDTrGBLxf2i1BnCxXEhDVM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363 uniprotkb:Q13363 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248224|imex:IM-24135-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:QZSv8GPnDdMz9QqKYSMzyy8j9NY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJX2 uniprotkb:Q13363 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248214|imex:IM-24135-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:k8rTIiZo8BddDYdlQhzwWyqqp0A false sufficient binding region:7-597 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MY1-2 uniprotkb:Q13363 intact:EBI-21248199 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:q96my12(display_long)|uniprotkb:NOL4L(gene name)|psi-mi:NOL4L(display_short)|uniprotkb:C20orf112(gene name synonym)|uniprotkb:C20orf113(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248206|imex:IM-24135-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q96MY1-2(isoform-parent)|entrezgene/locuslink:140688(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:xAoXY5RzAwyK8aJvRhSgidkx7SY9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:dhtdfgmcIV/N94Fk1ufqrxIg394 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJX2 uniprotkb:Q13363-2 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248361|imex:IM-24135-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:BU2fee3ey0i3dhaOhIfwIBq9NvU false sufficient binding region:7-597 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q75N03 uniprotkb:X5DP20 intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|intact:EBI-28973894|ensembl:ENSP00000401277|uniprotkb:B7ZM03 intact:EBI-21248551 psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248616|imex:IM-24135-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000222597|ensembl:ENSP00000222597|ensembl:ENSP00000401277|ensembl:ENSG00000105879(gene)|ensembl:ENST00000440859(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|refseq:NP_079090.2|refseq:NP_001271220.1|entrezgene/locuslink:79872(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:W/52oJfN2/gv3VRR8Q//4xbIDZc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZUJ4 uniprotkb:Q14129 intact:EBI-2837036|uniprotkb:Q7Z3X6|uniprotkb:Q6P7E9|ensembl:ENSP00000341139 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:cc062_human(display_long)|uniprotkb:C3orf62(gene name)|psi-mi:C3orf62(display_short) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248608|imex:IM-24135-1051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940964.1|ensembl:ENST00000343010(transcript)|interpro:IPR031670|ensembl:ENSG00000188315(gene)|entrezgene/locuslink:375341(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4HIoTcBKu3UzuFL6IUiNXcT253o9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:HKcbPLy+OeawkLIPG5MhdiP45R0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:X5DP20 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-21248551 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248598|imex:IM-24135-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:bHzzqOwZLbVA+7/cSFvloAMzI6w false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H0I2 uniprotkb:X5DP20 intact:EBI-744099|uniprotkb:Q6UWD7|ensembl:ENSP00000243878 intact:EBI-21248551 psi-mi:enkd1_human(display_long)|uniprotkb:ENKD1(gene name)|psi-mi:ENKD1(display_short)|uniprotkb:C16orf48(gene name synonym)|uniprotkb:UNQ6410/PRO21183(orf name) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248590|imex:IM-24135-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115516.1|ensembl:ENSG00000124074(gene)|ensembl:ENST00000243878(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0097546"(ciliary base)|interpro:IPR027012|interpro:IPR027710|mint:Q9H0I2|entrezgene/locuslink:84080(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kLnlpnGpF+sgQ+umqiN1CIK/7wc9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:JRl8JIHjMvayAwlZ6L2MTivn29g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HBZ2 uniprotkb:Q14129 intact:EBI-765971|uniprotkb:O15024|uniprotkb:Q8IYC2|uniprotkb:B4DIS7|ensembl:ENSP00000307479 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:arnt2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short)|uniprotkb:KIAA0307(gene name synonym)|uniprotkb:BHLHE1(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 1(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248582|imex:IM-24135-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055677.3|ensembl:ENSG00000172379(gene)|ensembl:ENST00000303329(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR036638|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|entrezgene/locuslink:9915(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nXUG8CAT3vm2UZictlc3M86O/Uw9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:W9MkUpSa6STNASuarINjJ2Pz1a4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6RW13-2 uniprotkb:X5DP20 intact:EBI-11522760|ensembl:ENSP00000365816 intact:EBI-21248551 psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248574|imex:IM-24135-1049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:PNzVis/8puQZBJ562gCqZKc078s9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:MRoQbHafuArtAZEgsdiCvAVDbGU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08117-2 uniprotkb:X5DP20 intact:EBI-11741437|ensembl:ENSP00000221561 intact:EBI-21248551 psi-mi:q08117-2(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)|uniprotkb:AES-2(isoform synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248566|imex:IM-24135-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104964(gene)|ensembl:ENST00000221561(transcript)|uniprotkb:Q08117-2(isoform-parent)|intact:EBI-717810(isoform-parent)|entrezgene/locuslink:166(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Nrb311r8NRqcGyEJkPxvyjbpt6E9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:z1oY1hR8IvCH2D/un6YHn++WTCc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14-3 uniprotkb:X5DP20 intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295 intact:EBI-21248551 psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248556|imex:IM-24135-1231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:bI2eb/IMgxpTrioRenaQdtXD7H4 false sufficient binding region:674-1097 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50221 uniprotkb:Q7L576 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779|ensembl:ENSP00000481038|ensembl:ENSP00000499947|ensembl:ENSP00000500331 psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248543|imex:IM-24135-1047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity) refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749(gene)|ensembl:ENSG00000288461(gene)|ensembl:ENST00000610365(transcript)|ensembl:ENST00000617928(transcript)|ensembl:ENST00000671714(transcript)|ensembl:ENST00000672091(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031209"(SCAR complex)|go:"GO:0005576"(extracellular region)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0005829"(cytosol)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N|entrezgene/locuslink:23191(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606 rigid:ZEhRcmOmeI11kfE6zs1RtMrAqnQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JST6 uniprotkb:Q7L576 intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232 intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779|ensembl:ENSP00000481038|ensembl:ENSP00000499947|ensembl:ENSP00000500331 psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short) psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248535|imex:IM-24135-843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity) refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749(gene)|ensembl:ENSG00000288461(gene)|ensembl:ENST00000610365(transcript)|ensembl:ENST00000617928(transcript)|ensembl:ENST00000671714(transcript)|ensembl:ENST00000672091(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031209"(SCAR complex)|go:"GO:0005576"(extracellular region)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0005829"(cytosol)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N|entrezgene/locuslink:23191(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606 rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606 rigid:QO3204vRWx8EU6/7AabLGQ4kwJU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99592 uniprotkb:Q13363-2 intact:EBI-3232046|uniprotkb:Q9UD99|uniprotkb:Q5VU40|uniprotkb:Q13397|uniprotkb:A8K5U3|uniprotkb:Q8N463|ensembl:ENSP00000481278 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:zbt18_human(display_long)|uniprotkb:ZBTB18(gene name)|psi-mi:ZBTB18(display_short)|uniprotkb:58 kDa repressor protein(gene name synonym)|uniprotkb:RP58(gene name synonym)|uniprotkb:TAZ1(gene name synonym)|uniprotkb:Transcriptional repressor RP58(gene name synonym)|uniprotkb:Translin-associated zinc finger protein 1(gene name synonym)|uniprotkb:ZNF238(gene name synonym)|uniprotkb:Zinc finger protein 238(gene name synonym)|uniprotkb:Zinc finger protein C2H2-171(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248527|imex:IM-24135-841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006343.2|refseq:NP_991331.1|refseq:NP_001265125.1|refseq:XP_005273063.1|refseq:XP_016855549.1|ensembl:ENSG00000179456(gene)|ensembl:ENST00000622512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:10472(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:b3uv5xKwJdwq0lxg0znSvWdcBN89606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:oxdUquRjqrTY0AxxZjuWeJRqvx0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60315 uniprotkb:Q13363-2 intact:EBI-717614|uniprotkb:A0JP09|uniprotkb:Q9UED1|uniprotkb:B7Z2P2|uniprotkb:F5H814|ensembl:ENSP00000386854|ensembl:ENSP00000454157|ensembl:ENSP00000487174 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:zeb2_human(display_long)|uniprotkb:Zinc finger homeobox protein 1b(gene name synonym)|uniprotkb:Smad-interacting protein 1(gene name synonym)|uniprotkb:ZEB2(gene name)|psi-mi:ZEB2(display_short)|uniprotkb:KIAA0569(gene name synonym)|uniprotkb:SIP1(gene name synonym)|uniprotkb:ZFX1B(gene name synonym)|uniprotkb:HRIHFB2411(orf name)|uniprotkb:ZFHX1B(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248519|imex:IM-24135-839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001165124.1|refseq:NP_055610.1|ensembl:ENST00000409487(transcript)|ensembl:ENST00000558170(transcript)|ensembl:ENST00000627532(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000169554(gene)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097324"(melanocyte migration)|go:"GO:1903056"(regulation of melanosome organization)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O60315|rcsb pdb:2DA7|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|refseq:XP_006712944.1|refseq:XP_006712945.1|entrezgene/locuslink:9839(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:KIKq943mmyO6wbsDamXsyo0OnEo9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:GUGt/+sraVzZjgqpBCujV9+o9WI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15884-3 uniprotkb:Q13363-2 intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248511|imex:IM-24135-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:/Ry/6DX/H73eRqDT6nfBpQAg64g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11953272 uniprotkb:Q13363-2 - intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:rnf111(display_short)|psi-mi:EBI-11953272(display_long) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248503|imex:IM-24135-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:54778(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V6Dzr4m6Ez2P3TbBAdJXsuRzJ7w9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:dTXlLkBO9Vn4pqBW+Yztq54rmwY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y5P3 uniprotkb:Q13363-2 intact:EBI-746228|uniprotkb:Q8N6X7|uniprotkb:B1B1K2|ensembl:ENSP00000333456|ensembl:ENSP00000353106|ensembl:ENSP00000401323|ensembl:ENSP00000444210|uniprotkb:B4DQM9|uniprotkb:E7EMN4 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:rai2_human(display_long)|uniprotkb:RAI2(gene name)|psi-mi:RAI2(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248495|imex:IM-24135-1045 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001166214.1|refseq:XP_011543741.1|refseq:XP_011543742.1|refseq:XP_011543743.1|ensembl:ENSG00000131831(gene)|ensembl:ENST00000331511(transcript)|ensembl:ENST00000360011(transcript)|ensembl:ENST00000451717(transcript)|ensembl:ENST00000545871(transcript)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR026092|mint:Q9Y5P3|refseq:NP_001166203.1|refseq:XP_006724522.1|refseq:XP_006724523.1|refseq:NP_001166210.1|refseq:NP_068557.3|entrezgene/locuslink:10742(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:cQ4QQAp6lbQjIvn9xzXPRfUBEzo9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:lkYuXu7/a5twg7vtufMaBxWHvJs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75928-2 uniprotkb:Q13363-2 intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248487|imex:IM-24135-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562." isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:vhfTHVj3rpjzIvTLYES5ZqSF7KA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48552 uniprotkb:Q13363-2 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248479|imex:IM-24135-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N|entrezgene/locuslink:8204(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:eUUL7koeHthAaHsW8mZKvzrEBc8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94818-2 uniprotkb:Q13363-2 intact:EBI-10190763|ensembl:ENSP00000465450 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:o94818-2(display_long)|uniprotkb:NOLP(gene name synonym)|uniprotkb:Nucleolar-localized protein(gene name synonym)|uniprotkb:HRIHFB2255(orf name)|uniprotkb:NOL4(gene name)|psi-mi:NOL4(display_short) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248469|imex:IM-24135-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94818-2(isoform-parent)|intact:EBI-726106(isoform-parent)|ensembl:ENSG00000101746(gene)|ensembl:ENST00000589544(transcript)|entrezgene/locuslink:8715(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Rj4dOxoGEPereK2BxupIYrcXAPI9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:Z6SZZJ3TfRZ48ijjtaODRxBdje8 false sufficient binding region:115-536 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TBB1 uniprotkb:Q13363-2 intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248461|imex:IM-24135-1229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:+O+y/jAFal7+Mm6Pr2FX+HwTTdU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYA8 uniprotkb:X5DP20 intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9 intact:EBI-21248551 psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248632|imex:IM-24135-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:0wCRpBmrL3oEMehmMViQNvDoc/c false sufficient binding region:11-594 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UFD9 uniprotkb:X5DP20 intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386 intact:EBI-21248551 psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248944|imex:IM-24135-1241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:QaGUJ1Gv8LxMZqj15tqSpDZW3Tk false sufficient binding region:838-1639 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5DP20 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21248551 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248928|imex:IM-24135-1239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:Ho5ETOdt16AXwmUvv01v5urNnyE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJ41-4 uniprotkb:X5DP20 intact:EBI-14093916 intact:EBI-21248551 psi-mi:q9uj41-4(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)|uniprotkb:RABEX5(gene name synonym)|uniprotkb:RAP1(gene name synonym)|uniprotkb:Rabaptin-5-associated exchange factor for Rab5(gene name synonym)|uniprotkb:Rabex-5(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248918|imex:IM-24135-1237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-913954(isoform-parent)|uniprotkb:Q9UJ41-4(isoform-parent)|entrezgene/locuslink:27342(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Df+MKsb2iU0r7o1/nppPWmRu3sk9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:a3kHgAmXi1jsXCvuUl5mTbJP3mo false sufficient binding region:15-505 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZV8 uniprotkb:Q14129 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248910|imex:IM-24135-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:qeKw4OjlVTKQBX9mPJhURQJSoBc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NR12 uniprotkb:X5DP20 intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099 intact:EBI-21248551 psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248902|imex:IM-24135-1061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENST00000355572|ensembl:ENSP00000347776|ensembl:ENSP00000348099|ensembl:ENST00000359895|ensembl:ENSP00000352964|ensembl:ENST00000393551|ensembl:ENSP00000377182|ensembl:ENST00000486828|ensembl:ENSP00000439157|ensembl:ENST00000493815|ensembl:ENSP00000431236|ensembl:ENSG00000196923(gene)|ensembl:ENST00000355841(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031941"(filamentous actin)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|rcsb pdb:2Q3G|reactome:R-HSA-8853659|entrezgene/locuslink:9260(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:2b2In3/Xtu2yQVxb5EwiIEGy/gQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P37198 uniprotkb:Q14129 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248894|imex:IM-24135-1059 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:31w7mzL4hQcyCa52pW33f5QAYl0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3B4 uniprotkb:Q14129 intact:EBI-741048|uniprotkb:Q96EA7|uniprotkb:Q9NVL5|uniprotkb:Q9P0I1|uniprotkb:B2RCK7|intact:EBI-10966427|uniprotkb:B4DT35|ensembl:ENSP00000264883 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:nup54_human(display_long)|uniprotkb:54 kDa nucleoporin(gene name synonym)|uniprotkb:NUP54(gene name)|psi-mi:NUP54(display_short) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248884|imex:IM-24135-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059122.2|refseq:NP_001265532.1|ensembl:ENSG00000138750(gene)|ensembl:ENST00000264883(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006605"(protein targeting)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q7Z3B4|rcsb pdb:4JNU|rcsb pdb:4JNV|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|entrezgene/locuslink:53371(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/X2b8J20uRh86bEeCc1tJSRuaIM9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:z0X+4jNpXfZN6AeNA9uW84NOWvs false sufficient binding region:1-493 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P16083 uniprotkb:Q14129 intact:EBI-358466|uniprotkb:B2R492|ensembl:ENSP00000337773|ensembl:ENSP00000369795|ensembl:ENSP00000369822|uniprotkb:Q5TD04 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:nqo2_human(display_long)|uniprotkb:NQO2(gene name)|psi-mi:NQO2(display_short)|uniprotkb:NMOR2(gene name synonym)|uniprotkb:NRH dehydrogenase [quinone] 2(gene name synonym)|uniprotkb:"NRH:quinone oxidoreductase 2"(gene name synonym)|uniprotkb:Quinone reductase 2(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248876|imex:IM-24135-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1QR2|rcsb pdb:1SG0|go:"GO:0031404"(chloride ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071949"(FAD binding)|go:"GO:1901662"(quinone catabolic process)|go:"GO:1904408"(melatonin binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905594"(resveratrol binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR029039|refseq:NP_000895.2|ensembl:ENSG00000124588(gene)|ensembl:ENST00000338130(transcript)|ensembl:ENST00000380430(transcript)|ensembl:ENST00000380455(transcript)|go:"GO:0001512"(dihydronicotinamide riboside quinone reductase activity)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016661"(oxidoreductase activity, acting on other nitrogenous compounds as donors)|refseq:NP_001305869.1|refseq:NP_001277150.1|rcsb pdb:1XI2|rcsb pdb:1ZX1|rcsb pdb:2BZS|rcsb pdb:2QMY|rcsb pdb:2QMZ|rcsb pdb:2QR2|rcsb pdb:2QWX|rcsb pdb:2QX4|rcsb pdb:2QX6|rcsb pdb:2QX8|rcsb pdb:2QX9|rcsb pdb:3FW1|rcsb pdb:3G5M|rcsb pdb:3GAM|rcsb pdb:3NFR|rcsb pdb:3NHF|rcsb pdb:3NHJ|rcsb pdb:3NHK|rcsb pdb:3NHL|rcsb pdb:3NHP|rcsb pdb:3NHR|rcsb pdb:3NHS|rcsb pdb:3NHW|rcsb pdb:3NHY|rcsb pdb:3O2N|rcsb pdb:3O73|rcsb pdb:3OVM|rcsb pdb:3OWH|rcsb pdb:3OWX|rcsb pdb:3OX1|rcsb pdb:3OX2|rcsb pdb:3OX3|rcsb pdb:3TE7|rcsb pdb:3TEM|rcsb pdb:3TZB|rcsb pdb:3UXE|rcsb pdb:3UXH|rcsb pdb:4FGJ|rcsb pdb:4FGK|rcsb pdb:4FGL|rcsb pdb:4GQI|rcsb pdb:4GR9|rcsb pdb:4QOD|rcsb pdb:4QOE|rcsb pdb:4QOF|rcsb pdb:4QOG|rcsb pdb:4QOH|rcsb pdb:4QOI|rcsb pdb:4QOJ|rcsb pdb:4U7F|rcsb pdb:4U7G|rcsb pdb:4U7H|rcsb pdb:4XDG|rcsb pdb:4XDH|rcsb pdb:4ZVK|rcsb pdb:4ZVL|rcsb pdb:4ZVM|rcsb pdb:4ZVN|rcsb pdb:5BUC|rcsb pdb:5LBT|rcsb pdb:5LBU|rcsb pdb:5LBW|rcsb pdb:5LBY|rcsb pdb:5LBZ|reactome:R-HSA-211945|rcsb pdb:3NHU|dip:DIP-39704N|entrezgene/locuslink:4835(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:e23niMWdj6fUH4WR3K6sUCTM0KE9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:RrRa3q2G2ZfYXlh7BQX51GtuUPI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3S9 uniprotkb:X5DP20 intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929 intact:EBI-21248551 psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248868|imex:IM-24135-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:CMuWvHjcww9C9XVLtWudMvmN4JY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z6G3-2 uniprotkb:X5DP20 intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040 intact:EBI-21248551 psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248858|imex:IM-24135-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:UE4WxDe59JWltks2qgGZshBVxVU false sufficient binding region:65-303 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15742 uniprotkb:X5DP20 intact:EBI-8641936|intact:EBI-28986032|ensembl:ENSP00000300131|uniprotkb:Q14797|uniprotkb:O76006|uniprotkb:B2RAK3|intact:MINT-8163249 intact:EBI-21248551 psi-mi:nab2_human(display_long)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)|uniprotkb:EGR-1-binding protein 2(gene name synonym)|uniprotkb:MADER(gene name synonym)|uniprotkb:Melanoma-associated delayed early response protein(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248850|imex:IM-24135-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166886(gene)|ensembl:ENST00000300131(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038398|interpro:IPR039040|mint:Q15742|reactome:R-HSA-9031628|reactome:R-HSA-9619665|ensembl:ENSP00000300131|ensembl:ENST00000342556|ensembl:ENSP00000341491|refseq:NP_005958.1|refseq:NP_001317234.1|entrezgene/locuslink:4665(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vj6P9S6D3S72qXfd7K7X5gC9bGI9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:wWWIySq4UUT5gKTtCy429DddbKk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TD10 uniprotkb:X5DP20 intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4 intact:EBI-21248551 psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248840|imex:IM-24135-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1|entrezgene/locuslink:145282(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:8XJq/kzrT4DrbuBa+7JWelH1saw false sufficient binding region:182-442 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJV3-2 uniprotkb:X5DP20 intact:EBI-10172526|ensembl:ENSP00000413976 intact:EBI-21248551 psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248830|imex:IM-24135-855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:aRaFCCacm0artezBIebx1Hg8vKs false sufficient binding region:21-705 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DP20 intact:EBI-16439278 intact:EBI-21248551 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248822|imex:IM-24135-853 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:PJfZyfDEI6CwckqjZ/XiWrDd3cY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14770-4 uniprotkb:X5DP20 intact:EBI-8025850|ensembl:ENSP00000341400|intact:MINT-4841606 intact:EBI-21248551 psi-mi:o14770-4(display_long)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:Meis2D(isoform synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short)|uniprotkb:MRG1(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248814|imex:IM-24135-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134138(gene)|ensembl:ENST00000338564(transcript)|intact:EBI-2804934(isoform-parent)|uniprotkb:O14770-4(isoform-parent)|entrezgene/locuslink:4212(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:bmX3MQjtyXhYf4495rfBgcY7wys9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:lJDMow1tEdIFJoWxJFW42MWUA3c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:X5DP20 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-21248551 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248806|imex:IM-24135-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1|entrezgene/locuslink:51562(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:7BompqPU3q9i5TuuAnDLr49oCSw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:X5DP20 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-21248551 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248798|imex:IM-24135-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:h3LP8xwpBxiT3n+E4Uryk/xE9Sw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q53G59 uniprotkb:Q14129 intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248790|imex:IM-24135-851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:HA7vrEMUbnkLhV/VnHDi6Kw/MLU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P2H0 uniprotkb:X5DP20 intact:EBI-473176|intact:EBI-28985617|ensembl:ENSP00000263468|uniprotkb:Q4G0U6 intact:EBI-21248551 psi-mi:ce126_human(display_long)|uniprotkb:CEP126(gene name)|psi-mi:CEP126(display_short)|uniprotkb:KIAA1377(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248782|imex:IM-24135-1235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110318(gene)|ensembl:ENST00000263468(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR028257|ensembl:ENSP00000263468|refseq:NP_065853.3|entrezgene/locuslink:57562(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:LWJUSNXNcLlsjkgbuvTm9bdTKOw9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:8lWqC2YjRO+oyk3x0qkVtUp6mQk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14687 uniprotkb:X5DP20 intact:EBI-372619|uniprotkb:Q8IY61|uniprotkb:Q96GA4|uniprotkb:Q9BW09|uniprotkb:D3DUM4|ensembl:ENSP00000253458 intact:EBI-21248551 psi-mi:gse1_human(display_long)|uniprotkb:GSE1(gene name)|psi-mi:GSE1(display_short)|uniprotkb:KIAA0182(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248772|imex:IM-24135-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127945.1|refseq:NP_055430.1|refseq:NP_001265113.1|ensembl:ENSG00000131149(gene)|ensembl:ENST00000253458(transcript)|interpro:IPR022207|interpro:IPR042337|entrezgene/locuslink:23199(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:demu8MwWIxvbEfrM+pBn3gDTUO09606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:OuctON2gFpYxw4L+Ogx0sSfQP7g false sufficient binding region:105-1217 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKT9 uniprotkb:X5DP20 intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544 intact:EBI-21248551 psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248764|imex:IM-24135-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:oNVo9LL3QDbjPpGjUIzG9pxl90U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11957986 uniprotkb:X5DP20 - intact:EBI-21248551 psi-mi:homez(display_short)|psi-mi:EBI-11957986(display_long) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248756|imex:IM-24135-849 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:57594(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:pQLRUATtfhRxD9ugVFmKu+SJGB89606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:9HFkP5pM7xPQi+EYbpi7nEe6Ga0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14964 uniprotkb:X5DP20 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-21248551 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248748|imex:IM-24135-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:oPEHngvlF86oF7ukw7QVv/X+llU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:X5DP20 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-21248551 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248738|imex:IM-24135-1057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:dX+7ALM0r1MJIeSoRhkjJl5/IHM false sufficient binding region:13-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TES7-6 uniprotkb:X5DP20 intact:EBI-10244131|ensembl:ENSP00000490726 intact:EBI-21248551 psi-mi:q8tes7-6(display_long)|uniprotkb:ALB(gene name synonym)|uniprotkb:KIAA1863(gene name synonym)|uniprotkb:Protein albatross(gene name synonym)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248728|imex:IM-24135-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2350063(isoform-parent)|uniprotkb:Q8TES7-6(isoform-parent)|ensembl:ENSG00000188878(gene)|ensembl:ENST00000636174(transcript)|entrezgene/locuslink:85302(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:KIglkj3GZjNlB7YecfDhjdVqGBw9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:odWKQjjmIQ+xERwX0gjM61cqtdQ false sufficient binding region:705-1148 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JST6 uniprotkb:X5DP20 intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232 intact:EBI-21248551 psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248720|imex:IM-24135-847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:7Jctdu4ALxUySJuD3WF0YShvfIA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95967 uniprotkb:Q14129 intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248712|imex:IM-24135-1233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:njD+n9COyAog7koD3qyT0XsZw2Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NF50 uniprotkb:X5DP20 intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681 intact:EBI-21248551 psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248702|imex:IM-24135-1055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1|entrezgene/locuslink:81704(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:jGASQJmoMCNUSK+1ueJd9e+zqHk false sufficient binding region:1587-2099 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ULA0 uniprotkb:X5DP20 intact:EBI-748356|uniprotkb:Q9BW44|uniprotkb:Q9NUV5|uniprotkb:Q9NV55|ensembl:ENSP00000273075 intact:EBI-21248551 psi-mi:dnpep_human(display_long)|uniprotkb:ASPEP(gene name synonym)|uniprotkb:DAP(gene name synonym)|uniprotkb:DNPEP(gene name)|psi-mi:DNPEP(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248694|imex:IM-24135-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306049.1|refseq:NP_036232.2|ensembl:ENSG00000123992(gene)|ensembl:ENST00000273075(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|rcsb pdb:4DYO|entrezgene/locuslink:23549(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2020/10/21 rogid:xG06vZosglPmA5ktZd8A8EH9h0g9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:UpBftdG8glF3Zwl3CFRAGJJp4ik false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:Q14129 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248686|imex:IM-24135-1053 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:fPfa2Pvd9s+NM2I6cqDsOwYIz9s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P1A6-3 uniprotkb:Q14129 intact:EBI-12019838 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:q9p1a6-3(display_long)|uniprotkb:C8orf68(gene name synonym)|uniprotkb:ERICH1-AS1(gene name synonym)|uniprotkb:DLGAP2(gene name)|psi-mi:DLGAP2(display_short)|uniprotkb:DAP2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248678|imex:IM-24135-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1753397(isoform-parent)|uniprotkb:Q9P1A6-3(isoform-parent)|entrezgene/locuslink:9228(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kh1ebyV49QdbaEIxzVEw59bO66A9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:7zJTfrr03E2e1iQHXD9QgF7D8VI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:Q14129 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-12206931|ensembl:ENSP00000331681|uniprotkb:B2RCH5|uniprotkb:D3DX15|uniprotkb:G5E9J8|uniprotkb:Q9BY28 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:dgcr6_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short)|uniprotkb:DiGeorge syndrome critical region 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248670|imex:IM-24135-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) ensembl:ENSG00000183628(gene)|ensembl:ENST00000331444(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031012"(extracellular matrix)|interpro:IPR010849(DiGeorge syndrome critical 6)|refseq:NP_005666.2|refseq:XP_006724997.1|entrezgene/locuslink:8214(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:znJTuX/3Z0qNTuQgvPcXkG6n6BE9606 rigid:49ORcl34a5ywxXlF9kcWNTUpmrE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96PC5-13 uniprotkb:X5DP20 intact:EBI-21248652|ensembl:ENSP00000452562 intact:EBI-21248551 psi-mi:q96pc5-13(display_long)|uniprotkb:MIA2(gene name)|psi-mi:MIA2(display_short)|uniprotkb:CTAGE5(gene name synonym)|uniprotkb:MEA11(gene name synonym)|uniprotkb:MEA6(gene name synonym)|uniprotkb:MGEA11(gene name synonym)|uniprotkb:MGEA6(gene name synonym)|uniprotkb:CTAGE family member 5 ER export factor(gene name synonym)|uniprotkb:Meningioma-expressed antigen 6/11(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen 5(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248662|imex:IM-24135-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150527(gene)|ensembl:ENST00000556148(transcript)|intact:EBI-1050253(isoform-parent)|entrezgene/locuslink:4253(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Q+v/ZdGY5LO4wRiMt8EAtJME1vY9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:WDrj//HkwoMTArsoo41KncHvpvU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05D60 uniprotkb:X5DP20 intact:EBI-748597|uniprotkb:Q8NEF1|uniprotkb:Q96LL7|intact:EBI-10177066|uniprotkb:E9PJR5|ensembl:ENSP00000298050 intact:EBI-21248551 psi-mi:deup1_human(display_long)|uniprotkb:CCDC67(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 67(gene name synonym)|uniprotkb:DEUP1(gene name)|psi-mi:DEUP1(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248642|imex:IM-24135-845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_857596.2|refseq:XP_005273859.1|ensembl:ENSG00000165325(gene)|ensembl:ENST00000298050(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|interpro:IPR029611|interpro:IPR031470|go:"GO:0030030"(cell projection organization)|entrezgene/locuslink:159989(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/d2HVFtI68hr7u7nqJdBUwn06bE9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:do+vwpAZzTS7iEz8LPDE5QweahQ false sufficient binding region:9-363 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N5R6 uniprotkb:X5DP20 intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976 intact:EBI-21248551 psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248624|imex:IM-24135-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2021/11/30 rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:246gN8/UD0REktKWb78Rb07Ldps false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NQZ6 uniprotkb:X5DP20 intact:EBI-747993|uniprotkb:Q5JTF9|uniprotkb:Q9H9C3|uniprotkb:Q9H9H7|uniprotkb:Q9ULQ4|uniprotkb:B2RDC2|uniprotkb:B4DED0|uniprotkb:E7EM74|uniprotkb:B3KVZ5|uniprotkb:G3V1L3|uniprotkb:Q53H73|ensembl:ENSP00000363972 intact:EBI-21248551 psi-mi:zc4h2_human(display_long)|uniprotkb:ZC4H2(gene name)|psi-mi:ZC4H2(display_short)|uniprotkb:KIAA1166(gene name synonym)|uniprotkb:HCA127(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 127(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249050|imex:IM-24135-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171503.1|refseq:NP_061154.1|refseq:NP_001230733.1|refseq:NP_001171504.1|ensembl:ENSG00000126970(gene)|ensembl:ENST00000374839(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR018482|interpro:IPR044069|entrezgene/locuslink:55906(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:lQr6Z1Cs3RuhckvFry86sAyycBE9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:tlrP/EOw+umCRIpj4lS3chCIGms false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O96006 uniprotkb:X5DP20 intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725 intact:EBI-21248551 psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249042|imex:IM-24135-859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:DnFwo4se93u1qz6ifkhXE6ujwMQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55072 uniprotkb:X5DP20 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 intact:EBI-21248551 psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249034|imex:IM-24135-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|entrezgene/locuslink:7415(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:WbUVwb1rh/56mH49+fZJ0TaiEMg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UGJ1-2 uniprotkb:X5DP20 intact:EBI-10964469|ensembl:ENSP00000456648 intact:EBI-21248551 psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249026|imex:IM-24135-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:7S0WscQ48LYGo5GHfpPyDwCLNC4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:X5DP20 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-21248551 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249018|imex:IM-24135-857 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:ssBkdRhRrUmhB2sq+12LzqRuuaU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:X5DP20 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-21248551 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249010|imex:IM-24135-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:i+334/BO4AamfHeMYuT+iYGL0YQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13077 uniprotkb:X5DP20 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-21248551 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249002|imex:IM-24135-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:Sa0xYOO94rGp1U0S452CCByDjjA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:X5DP20 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-21248551 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248994|imex:IM-24135-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:oAabes9r5qGhKSeX+8qGvUBxoSQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15884-3 uniprotkb:X5DP20 intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670 intact:EBI-21248551 psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248986|imex:IM-24135-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:TK2T0ZVkMtdWEFHpXEyXvC9mY74 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99081-3 uniprotkb:X5DP20 intact:EBI-11952764|ensembl:ENSP00000331057|ensembl:ENSP00000388940 intact:EBI-21248551 psi-mi:q99081-3(display_long)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:c(isoform synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248978|imex:IM-24135-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-722877(isoform-parent)|uniprotkb:Q99081-3(isoform-parent)|ensembl:ENSG00000140262(gene)|ensembl:ENST00000333725(transcript)|ensembl:ENST00000438423(transcript)|entrezgene/locuslink:6938(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Sz84TChPfDPpa01k4znWJvWbQWU9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:aZAQoX36HzsFErp0q5XO9Gs2yOc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75177-5 uniprotkb:X5DP20 intact:EBI-12035119 intact:EBI-21248551 psi-mi:o75177-5(display_long)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym)|uniprotkb:SYT homolog 1(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248970|imex:IM-24135-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O75177-5(isoform-parent)|intact:EBI-744674(isoform-parent)|entrezgene/locuslink:26039(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:O8Tk/1TY5RVlu3StfzEbjQoI2wE9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:W1zdB1WHrAQ+mKlnSMVYSa0uMl0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43597 uniprotkb:X5DP20 intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9 intact:EBI-21248551 psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248962|imex:IM-24135-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:u1omauzisc6MdZlogMotUmtauSI9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:HVK1MqdTfK4Qey3sQKpBa2z3B8U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NA61-2 uniprotkb:X5DP20 intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148 intact:EBI-21248551 psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248954|imex:IM-24135-1063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:l64U3Gm/4IOB99a+H4p8dLTEyFE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8HWS3 uniprotkb:X5DP20 intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208 intact:EBI-21248551 psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21248936|imex:IM-24135-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:YQd3fnS9aAdNYInkLKwO0Kwu/sk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q92731 intact:EBI-16439278 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249314|imex:IM-24135-1069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76|entrezgene/locuslink:2100(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rigid:kMTy3uSBs4E64jP3VZcgBkhdRRI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TD17 uniprotkb:X5DP20 intact:EBI-8643207|ensembl:ENSP00000420418|intact:MINT-8163335|uniprotkb:Q8TD18|uniprotkb:A8K384|uniprotkb:B4E377|uniprotkb:Q9P2K7|uniprotkb:Q9UDV8 intact:EBI-21248551 psi-mi:zn398_human(display_long)|uniprotkb:ZNF398(gene name)|psi-mi:ZNF398(display_short)|uniprotkb:KIAA1339(gene name synonym)|uniprotkb:ZER6(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein p52/p71(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249059|imex:IM-24135-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197024(gene)|ensembl:ENST00000475153(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:XP_011514743.1|refseq:NP_065832.1|refseq:NP_733787.1|entrezgene/locuslink:57541(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vmzhbFftKf8nNZm8D3fQFGfjHuI9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:qB4PJr+Ep5IAKAC74SI3MhaPBp4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:P06730 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249298|imex:IM-24135-863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:8+3FvyW/D4mUmxPLBQ/hRZCDG0c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48775 uniprotkb:P06730 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249290|imex:IM-24135-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:IgyLnRdvBRarZoUa25BGxZNE+Qo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZY3 uniprotkb:P06730 intact:EBI-2556193|uniprotkb:Q9H8S4|uniprotkb:Q6GUF5|uniprotkb:Q9NUP0|uniprotkb:Q3KQZ3|uniprotkb:B0I1P4|uniprotkb:Q9P210|ensembl:ENSP00000465650 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:kank2_human(display_long)|uniprotkb:ANKRD25(gene name synonym)|uniprotkb:KIAA1518(gene name synonym)|uniprotkb:MXRA3(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 25(gene name synonym)|uniprotkb:SRC-1-interacting protein(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 3(gene name synonym)|uniprotkb:KANK2(gene name)|psi-mi:KANK2(display_short) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249282|imex:IM-24135-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129663.1|refseq:NP_056308.3|rcsb pdb:6TMD|ensembl:ENSG00000197256(gene)|ensembl:ENST00000586659(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0070563"(negative regulation of vitamin D receptor signaling pathway)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|mint:Q63ZY3|rcsb pdb:4HBD|rcsb pdb:5YBV|refseq:NP_001316380.1|entrezgene/locuslink:25959(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:5lZ6UWmx5+N6B1B/xTmVfvxA7Ag9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:TVdY0OZoA3LSYK5M7gX23u6ZehI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRA8-2 uniprotkb:P06730 intact:EBI-11531709|ensembl:ENSP00000342927 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:q9nra8-2(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249274|imex:IM-24135-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000184708(gene)|ensembl:ENST00000344710(transcript)|intact:EBI-301024(isoform-parent)|uniprotkb:Q9NRA8-2(isoform-parent)|entrezgene/locuslink:56478(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VQghhcptYh8k783QTJChpGbP/lU9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:CVPZiV89FYzDgKqEstWWu4esLO4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60516 uniprotkb:P06730 intact:EBI-746950|ensembl:ENSP00000308472 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:4ebp3_human(display_long)|uniprotkb:EIF4EBP3(gene name)|psi-mi:EIF4EBP3(display_short) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249266|imex:IM-24135-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243056(gene)|ensembl:ENST00000310331(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030371"(translation repressor activity)|go:"GO:0045947"(negative regulation of translational initiation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|refseq:NP_003723.1|entrezgene/locuslink:8637(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HBaN9ARO+drtwcAq1Eo2qaNtNPI9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:brtzIOjkUdUqw4vVwwDGy2mSs2c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13542 uniprotkb:P06730 intact:EBI-935137|ensembl:ENSP00000362314 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:4ebp2_human(display_long)|uniprotkb:EIF4EBP2(gene name)|psi-mi:EIF4EBP2(display_short) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249258|imex:IM-24135-1243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004087.1|dip:DIP-36572N|ensembl:ENSG00000148730(gene)|ensembl:ENST00000373218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0007613"(memory)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0035176"(social behavior)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|mint:Q13542|rcsb pdb:2MX4|rcsb pdb:3AM7|entrezgene/locuslink:1979(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:EDzLBqy7pJvo45a3b6pHWOlRRQY9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:D/Upw8eExs+JVA6kQlUcZYEsDVI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13541 uniprotkb:P06730 intact:EBI-74090|uniprotkb:B2R502|uniprotkb:Q6IBN3|uniprotkb:D3DSW8|ensembl:ENSP00000340691 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:4ebp1_human(display_long)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)|uniprotkb:EIF4EBP1(gene name)|psi-mi:EIF4EBP1(display_short) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249250|imex:IM-24135-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004086.1|ensembl:ENSP00000340691|ensembl:ENSG00000187840(gene)|ensembl:ENST00000338825(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-30944N|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|mint:Q13541|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1WKW|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:3HXG|rcsb pdb:3HXI|rcsb pdb:3M93|rcsb pdb:3M94|rcsb pdb:3U7X|rcsb pdb:4UED|rcsb pdb:5BXV|rcsb pdb:5EKV|rcsb pdb:5NVN|rcsb pdb:5WBJ|rcsb pdb:6BCU|rcsb pdb:6BCX|reactome:R-HSA-166208|reactome:R-HSA-72662|entrezgene/locuslink:1978(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:abkjWitYZ9erPSlC88IWI2FtKto9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:bvdQml+G9vNtk+1ZjEwvGmNkPqk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRA8-2 uniprotkb:P06730-3 intact:EBI-11531709|ensembl:ENSP00000342927 intact:EBI-21249211 psi-mi:q9nra8-2(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short) psi-mi:p067303(display_long)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249242|imex:IM-24135-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000184708(gene)|ensembl:ENST00000344710(transcript)|intact:EBI-301024(isoform-parent)|uniprotkb:Q9NRA8-2(isoform-parent)|entrezgene/locuslink:56478(identity) uniprotkb:P06730-3(isoform-parent)|entrezgene/locuslink:1977(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VQghhcptYh8k783QTJChpGbP/lU9606 rogid:0WUp4q45YzjX5mmyoDH0fB2HAHY9606 rigid:ywJ3Y5rL3ZwiAe2auzhN581Bcvo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60516 uniprotkb:P06730-3 intact:EBI-746950|ensembl:ENSP00000308472 intact:EBI-21249211 psi-mi:4ebp3_human(display_long)|uniprotkb:EIF4EBP3(gene name)|psi-mi:EIF4EBP3(display_short) psi-mi:p067303(display_long)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249234|imex:IM-24135-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243056(gene)|ensembl:ENST00000310331(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030371"(translation repressor activity)|go:"GO:0045947"(negative regulation of translational initiation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|refseq:NP_003723.1|entrezgene/locuslink:8637(identity) uniprotkb:P06730-3(isoform-parent)|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HBaN9ARO+drtwcAq1Eo2qaNtNPI9606 rogid:0WUp4q45YzjX5mmyoDH0fB2HAHY9606 rigid:trPMKthSoa/hA7StGsDPZ+chrhg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13542 uniprotkb:P06730-3 intact:EBI-935137|ensembl:ENSP00000362314 intact:EBI-21249211 psi-mi:4ebp2_human(display_long)|uniprotkb:EIF4EBP2(gene name)|psi-mi:EIF4EBP2(display_short) psi-mi:p067303(display_long)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249226|imex:IM-24135-1067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004087.1|dip:DIP-36572N|ensembl:ENSG00000148730(gene)|ensembl:ENST00000373218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0007613"(memory)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0035176"(social behavior)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|mint:Q13542|rcsb pdb:2MX4|rcsb pdb:3AM7|entrezgene/locuslink:1979(identity) uniprotkb:P06730-3(isoform-parent)|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:EDzLBqy7pJvo45a3b6pHWOlRRQY9606 rogid:0WUp4q45YzjX5mmyoDH0fB2HAHY9606 rigid:XlELcYvrq8p9jNJjPfBP/Pwib6E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13541 uniprotkb:P06730-3 intact:EBI-74090|uniprotkb:B2R502|uniprotkb:Q6IBN3|uniprotkb:D3DSW8|ensembl:ENSP00000340691 intact:EBI-21249211 psi-mi:4ebp1_human(display_long)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)|uniprotkb:EIF4EBP1(gene name)|psi-mi:EIF4EBP1(display_short) psi-mi:p067303(display_long)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249218|imex:IM-24135-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004086.1|ensembl:ENSP00000340691|ensembl:ENSG00000187840(gene)|ensembl:ENST00000338825(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-30944N|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|mint:Q13541|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1WKW|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:3HXG|rcsb pdb:3HXI|rcsb pdb:3M93|rcsb pdb:3M94|rcsb pdb:3U7X|rcsb pdb:4UED|rcsb pdb:5BXV|rcsb pdb:5EKV|rcsb pdb:5NVN|rcsb pdb:5WBJ|rcsb pdb:6BCU|rcsb pdb:6BCX|reactome:R-HSA-166208|reactome:R-HSA-72662|entrezgene/locuslink:1978(identity) uniprotkb:P06730-3(isoform-parent)|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:abkjWitYZ9erPSlC88IWI2FtKto9606 rogid:0WUp4q45YzjX5mmyoDH0fB2HAHY9606 rigid:fIzxYsjF1aCIhHvq4fNORwh71ZE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HD26-2 uniprotkb:Q12882-2 intact:EBI-11102276|ensembl:ENSP00000052569 intact:EBI-21249198 psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym) psi-mi:q128822(display_long)|uniprotkb:DPYD(gene name)|psi-mi:DPYD(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249203|imex:IM-24135-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity) uniprotkb:Q12882-2(isoform-parent)|entrezgene/locuslink:1806(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606 rogid:zGy1/Nroyhc6z/dnvYnuer3bI1Y9606 rigid:uTwHV1jREC/2W6JDDiMVgSUmOTc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TF42 uniprotkb:Q14183 intact:EBI-1380492|uniprotkb:Q53GT5|uniprotkb:Q53GT8|uniprotkb:Q8NBV7|uniprotkb:Q96IG9|uniprotkb:Q96NZ2|ensembl:ENSP00000284273 intact:EBI-20861623|ensembl:ENSP00000340017|ensembl:ENSP00000455196|ensembl:ENSP00000455624|ensembl:ENSP00000482870|uniprotkb:B4DEJ2|uniprotkb:H3BNH6|uniprotkb:Q6P4G4|uniprotkb:Q7Z5G0|uniprotkb:Q8IVX0 psi-mi:ubs3b_human(display_long)|uniprotkb:UBASH3B(gene name)|psi-mi:UBASH3B(display_short)|uniprotkb:KIAA1959(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:Suppressor of T-cell receptor signaling 1(gene name synonym)|uniprotkb:Cbl-interacting protein p70(gene name synonym)|uniprotkb:T-cell ubiquitin ligand 2(gene name synonym)|uniprotkb:Tyrosine-protein phosphatase STS1/TULA2(gene name synonym) psi-mi:doc2a_human(display_long)|uniprotkb:DOC2A(gene name)|psi-mi:DOC2A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249190|imex:IM-24135-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116262.2|ensembl:ENSG00000154127(gene)|ensembl:ENST00000284273(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090331"(negative regulation of platelet aggregation)|interpro:IPR001452(Src homology-3)|interpro:IPR009060(UBA-like)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029033|interpro:IPR035632|interpro:IPR036028|mint:Q8TF42|rcsb pdb:2CPW|rcsb pdb:2E5K|rcsb pdb:5VR6|rcsb pdb:5W5G|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:84959(identity) ensembl:ENSG00000149927(gene)|ensembl:ENST00000350119(transcript)|ensembl:ENST00000564944(transcript)|ensembl:ENST00000564979(transcript)|ensembl:ENST00000616445(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005764"(lysosome)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030054"(cell junction)|go:"GO:0043005"(neuron projection)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR014638(Double C2 protein, alpha/beta/gamma type)|interpro:IPR030535|interpro:IPR035892|interpro:IPR043566|rcsb pdb:4MJJ|go:"GO:0007399"(nervous system development)|refseq:NP_001268991.1|refseq:NP_001268992.1|refseq:NP_001268997.1|refseq:NP_003577.2|refseq:XP_011544277.1|refseq:XP_016879265.1|refseq:XP_016879266.1|entrezgene/locuslink:8448(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:rInBY4dNsLDJJPjZQqMSkuKJwns9606 rogid:HO5xk9bz6q9C9wesF5THrWvY4M89606 rigid:y5rPdJ2SnQOMLCaBMpZ8zwASwwc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52306-5 uniprotkb:Q14183 intact:EBI-12832744|ensembl:ENSP00000340454 intact:EBI-20861623|ensembl:ENSP00000340017|ensembl:ENSP00000455196|ensembl:ENSP00000455624|ensembl:ENSP00000482870|uniprotkb:B4DEJ2|uniprotkb:H3BNH6|uniprotkb:Q6P4G4|uniprotkb:Q7Z5G0|uniprotkb:Q8IVX0 psi-mi:p52306-5(display_long)|uniprotkb:RAP1GDS1(gene name)|psi-mi:RAP1GDS1(display_short)|uniprotkb:Exchange factor smgGDS(gene name synonym)|uniprotkb:SMG GDS protein(gene name synonym)|uniprotkb:SMG P21 stimulatory GDP/GTP exchange protein(gene name synonym) psi-mi:doc2a_human(display_long)|uniprotkb:DOC2A(gene name)|psi-mi:DOC2A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249182|imex:IM-24135-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138698(gene)|ensembl:ENST00000339360(transcript)|uniprotkb:P52306-5(isoform-parent)|intact:EBI-746389(isoform-parent)|entrezgene/locuslink:5910(identity) ensembl:ENSG00000149927(gene)|ensembl:ENST00000350119(transcript)|ensembl:ENST00000564944(transcript)|ensembl:ENST00000564979(transcript)|ensembl:ENST00000616445(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005764"(lysosome)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030054"(cell junction)|go:"GO:0043005"(neuron projection)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR014638(Double C2 protein, alpha/beta/gamma type)|interpro:IPR030535|interpro:IPR035892|interpro:IPR043566|rcsb pdb:4MJJ|go:"GO:0007399"(nervous system development)|refseq:NP_001268991.1|refseq:NP_001268992.1|refseq:NP_001268997.1|refseq:NP_003577.2|refseq:XP_011544277.1|refseq:XP_016879265.1|refseq:XP_016879266.1|entrezgene/locuslink:8448(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:YP+5o4OzDy4ZOi0VXpoq7nKlImc9606 rogid:HO5xk9bz6q9C9wesF5THrWvY4M89606 rigid:bjdEGFbT1rbS/c23Y0+Tqp+V2KQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43364 uniprotkb:Q09013-1 intact:EBI-21249133|ensembl:ENSP00000222718|uniprotkb:A1L4K3|uniprotkb:B2RMW3 intact:EBI-21249126 psi-mi:hxa2_human(display_long)|uniprotkb:Homeobox protein Hox-1K(gene name synonym)|uniprotkb:HOXA2(gene name)|psi-mi:HOXA2(display_short)|uniprotkb:HOX1K(gene name synonym) psi-mi:q090131(display_long)|uniprotkb:DMPK(gene name)|psi-mi:DMPK(display_short)|uniprotkb:DM1PK(gene name synonym)|uniprotkb:MDPK(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249174|imex:IM-24135-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105996(gene)|ensembl:ENST00000222718(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-5617472|reactome:R-HSA-9010553|refseq:NP_006726.1|entrezgene/locuslink:3199(identity) uniprotkb:Q09013-1(isoform-parent)|entrezgene/locuslink:1760(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WRTR8leN+sm4/brewa6Dtl/qdn89606 rogid:/ss7wrIr/SUZEV3OGKjwGEHd8wQ9606 rigid:2kW5xpQBuvIXQTrgbI2jN/hhbD8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DNE0 uniprotkb:Q9P1A6-3 intact:EBI-21247923 intact:EBI-12019838 psi-mi:x5dne0_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:q9p1a6-3(display_long)|uniprotkb:C8orf68(gene name synonym)|uniprotkb:ERICH1-AS1(gene name synonym)|uniprotkb:DLGAP2(gene name)|psi-mi:DLGAP2(display_short)|uniprotkb:DAP2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249118|imex:IM-24135-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035515|interpro:IPR040325|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) intact:EBI-1753397(isoform-parent)|uniprotkb:Q9P1A6-3(isoform-parent)|entrezgene/locuslink:9228(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NAAtZSEJ78WbTtGKgy+Xs1sZGBE9606 rogid:kh1ebyV49QdbaEIxzVEw59bO66A9606 rigid:m+8MUO0LrSxdf4v0WBa32S5190o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DP35 uniprotkb:X5DQV8 intact:EBI-21249101 intact:EBI-21249096 psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:x5dqv8_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249110|imex:IM-24135-1065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) interpro:IPR026081|entrezgene/locuslink:27185(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rogid:93TNKNHYhusDUfBCskGfHW9ZXOA9606 rigid:jnBF/8erMoylOe9nweXwnErRkbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DRE8 intact:EBI-16439278 intact:EBI-21249075 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dre8_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249088|imex:IM-24135-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:GZPNjOPXL0sy1ut824BUnxh4xX89606 rigid:bQr9Y+a9EeQC/1FgfGCXJTbRYE4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14964 uniprotkb:X5DRE8 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-21249075 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:x5dre8_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249080|imex:IM-24135-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:GZPNjOPXL0sy1ut824BUnxh4xX89606 rigid:Ux59dkFOG+x0+n9ijkkPhCn31w0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NWS9-2 uniprotkb:X5DP20 intact:EBI-740232|ensembl:ENSP00000478778 intact:EBI-21248551 psi-mi:q9nws9-2(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249067|imex:IM-24135-861 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083838(gene)|ensembl:ENST00000610298(transcript)|intact:EBI-3925851(isoform-parent)|uniprotkb:Q9NWS9-2(isoform-parent)|entrezgene/locuslink:55663(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7raxVklr1qjkhOSVcnfTXEJau3g9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:MVtv/hsB6qJ/b5I8am9WAC4ZswE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T124-6 uniprotkb:P06730 intact:EBI-11524408 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249306|imex:IM-24135-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|entrezgene/locuslink:1977(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rigid:rl7uSW1C3osAc5Sikay9T+NBlh8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:P78347-2 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249540|imex:IM-24135-873 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent)|entrezgene/locuslink:2969(identity) - isoform-comment:No experimental confirmation available. isoform-comment:Contains a phosphoserine at position 278. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:+4u+9PXnzXEE6SRk+/JxqwFCqBw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3S9 uniprotkb:Q92731 intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym) psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249322|imex:IM-24135-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76|entrezgene/locuslink:2100(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rigid:sbkWp+d9qrinsavhDClpIv1L2Uo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9C005 uniprotkb:P78347-2 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249524|imex:IM-24135-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|entrezgene/locuslink:84661(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent)|entrezgene/locuslink:2969(identity) - - isoform-comment:Contains a phosphoserine at position 278. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:nMUS/+D1S1fvMkPKJYpZmr0QzNo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63010-2 uniprotkb:P78347-2 intact:EBI-11529439|ensembl:ENSP00000482835|ensembl:ENSP00000483185 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:p63010-2(display_long)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249516|imex:IM-24135-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-432924(isoform-parent)|uniprotkb:P63010-2(isoform-parent)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000610402(transcript)|ensembl:ENST00000618940(transcript)|entrezgene/locuslink:163(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent)|entrezgene/locuslink:2969(identity) - - isoform-comment:Contains a phosphoserine at position 278. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:RpFHKbLgdxGqagTUoCCgQ2W+9nw9606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:RsqeKIKu2fKsjcofhH8mj7LcwOY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75928-2 uniprotkb:P78347-4 intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402 intact:EBI-11017280|ensembl:ENSP00000482476 psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:p78347-4(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249508|imex:IM-24135-1247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000621734(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-4(isoform-parent)|entrezgene/locuslink:2969(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562." isoform-comment:Contains a phosphoserine at position 298. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606 rogid:TY66urvQaBeoSqcLZ4NIV7QHcmY9606 rigid:bZw5M82VBE6gCPPi7JZkGmB3fIY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:P78347-4 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-11017280|ensembl:ENSP00000482476 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:p78347-4(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249500|imex:IM-24135-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000621734(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-4(isoform-parent)|entrezgene/locuslink:2969(identity) - isoform-comment:No experimental confirmation available. isoform-comment:Contains a phosphoserine at position 298. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:TY66urvQaBeoSqcLZ4NIV7QHcmY9606 rigid:2lm0Z8Gcqf9iyx1Ju5U7Vog7yGU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:P78347-3 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-2560462|ensembl:ENSP00000484526 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:p78347-3(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249492|imex:IM-24135-871 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000614986(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-3(isoform-parent)|entrezgene/locuslink:2969(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:c9/JE1T7G5dPM/NZmNydBOzsQok9606 rigid:+c6MZyVaeCM5qoLkfPnrfUiVSJA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96CN9 uniprotkb:P78347-3 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 intact:EBI-2560462|ensembl:ENSP00000484526 psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:p78347-3(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249484|imex:IM-24135-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000614986(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-3(isoform-parent)|entrezgene/locuslink:2969(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 rogid:c9/JE1T7G5dPM/NZmNydBOzsQok9606 rigid:uINyNswpvIOsAvPGB2Iuu5VVPGA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:P78347 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249476|imex:IM-24135-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N|entrezgene/locuslink:2969(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 rigid:VSAaTSUA+vaRZPBDDuBGjJAkxhk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96CN9 uniprotkb:P78347 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249468|imex:IM-24135-869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity) refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N|entrezgene/locuslink:2969(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 rigid:WTVvWtPK5yf4X4oRPTRlq5sOPAg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21266 uniprotkb:P09488 intact:EBI-350350|uniprotkb:O60550|uniprotkb:Q96HA3|ensembl:ENSP00000354357|ensembl:ENSP00000256594 intact:EBI-350409|uniprotkb:Q5GHG0|uniprotkb:Q6FH88|uniprotkb:Q9UC96|uniprotkb:Q8TC98|ensembl:ENSP00000311469 psi-mi:gstm3_human(display_long)|uniprotkb:GSTM3(gene name)|psi-mi:GSTM3(display_short)|uniprotkb:GST5(gene name synonym)|uniprotkb:GSTM3-3(gene name synonym)|uniprotkb:GST class-mu 3(gene name synonym) psi-mi:gstm1_human(display_long)|uniprotkb:GSTM1(gene name)|psi-mi:GSTM1(display_short)|uniprotkb:GST1(gene name synonym)|uniprotkb:GSTM1-1(gene name synonym)|uniprotkb:GST class-mu 1(gene name synonym)|uniprotkb:GSTM1a-1a(gene name synonym)|uniprotkb:GSTM1b-1b(gene name synonym)|uniprotkb:GST HB subunit 4(gene name synonym)|uniprotkb:GTH4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249460|imex:IM-24135-1077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000840.2|interpro:IPR036282|interpro:IPR040079|rcsb pdb:3GTU|reactome:R-HSA-156590|ensembl:ENST00000256594(transcript)|ensembl:ENST00000361066(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|ensembl:ENSG00000134202(gene)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|entrezgene/locuslink:2947(identity) refseq:NP_000552.2|refseq:NP_666533.1|ensembl:ENSG00000134184(gene)|ensembl:ENST00000309851(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:1901687"(glutathione derivative biosynthetic process)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR040079|rcsb pdb:1GTU|rcsb pdb:1XW6|rcsb pdb:1XWK|rcsb pdb:1YJ6|rcsb pdb:2F3M|reactome:R-HSA-156590|entrezgene/locuslink:2944(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9hGeWmuSdPCn0RGJo4mQ/w9tKzo9606 rogid:/cuHGWU57I+yHHaJM99UyWcAy4c9606 rigid:PA8hSnISwp3Bqga7gjP34upO8Bc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IZU0 uniprotkb:X5DQZ7 intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495 intact:EBI-21249444 psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short) psi-mi:x5dqz7_human(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249452|imex:IM-24135-867 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity) go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0006979"(response to oxidative stress)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR036249|entrezgene/locuslink:2876(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606 rogid:m7yoCs9KEw4MKLBimkhSWxt5fx09606 rigid:YhPYr1YzMUH3t5HUuzLOVC0rjGY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q04760 intact:EBI-16439278 intact:EBI-1055525|uniprotkb:P78375|uniprotkb:Q5TZW3|uniprotkb:Q96FC0|uniprotkb:Q96J41|uniprotkb:B4DDV0|uniprotkb:Q59EL0|uniprotkb:B2R6P7|ensembl:ENSP00000362463 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:lgul_human(display_long)|uniprotkb:Methylglyoxalase(gene name synonym)|uniprotkb:Aldoketomutase(gene name synonym)|uniprotkb:Glyoxalase I(gene name synonym)|uniprotkb:Ketone-aldehyde mutase(gene name synonym)|uniprotkb:S-D-lactoylglutathione methylglyoxal lyase(gene name synonym)|uniprotkb:GLO1(gene name)|psi-mi:GLO1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249436|imex:IM-24135-865 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_006699.2|ensembl:ENSG00000124767(gene)|ensembl:ENST00000373365(transcript)|go:"GO:0004462"(lactoylglutathione lyase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004360(Glyoxalase/bleomycin resistance protein/dioxygenase)|interpro:IPR004361(Glyoxalase I)|interpro:IPR018146|interpro:IPR029068|interpro:IPR037523|rcsb pdb:1BH5|rcsb pdb:1FRO|rcsb pdb:1QIN|rcsb pdb:1QIP|rcsb pdb:3VW9|rcsb pdb:3W0T|rcsb pdb:3W0U|reactome:R-HSA-70268|entrezgene/locuslink:2739(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:Oe1lCyzzD2y1WeArvZ74cYu9M1w9606 rigid:ZUEyJEbNkDHiD04gU7Tea+Vpf3U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:P28472 intact:EBI-16439278 intact:EBI-6258252|ensembl:ENSP00000308725|uniprotkb:B7Z2W1|uniprotkb:H7BYV8|uniprotkb:Q14352|uniprotkb:Q96FM5|uniprotkb:B7Z825|uniprotkb:F5H3D2 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:gbrb3_human(display_long)|uniprotkb:GABRB3(gene name)|psi-mi:GABRB3(display_short)|uniprotkb:"GABA(A) receptor subunit beta-3"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249428|imex:IM-24135-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) ensembl:ENSG00000166206(gene)|ensembl:ENST00000311550(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071420"(cellular response to histamine)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:4COF|rcsb pdb:5O8F|rcsb pdb:5OJM|rcsb pdb:6A96|rcsb pdb:6HUG|rcsb pdb:6HUJ|rcsb pdb:6HUK|rcsb pdb:6HUO|rcsb pdb:6HUP|rcsb pdb:6I53|reactome:R-HSA-1236394|reactome:R-HSA-977443|refseq:NP_000805.1|refseq:NP_001178249.1|refseq:NP_001178250.1|refseq:NP_068712.1|refseq:NP_001265560.1|dip:DIP-61029N|entrezgene/locuslink:2562(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:dgZJaPbhb7B3CLAyyV4O3jrEiHw9606 rigid:reWGT6GxZEb7eV0FrXf87YOdHHw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q02446 uniprotkb:Q75MZ5 intact:EBI-10198587|uniprotkb:Q32M52|uniprotkb:O60402|ensembl:ENSP00000222584 intact:EBI-10255915|ensembl:ENSP00000418100 psi-mi:sp4_human(display_long)|uniprotkb:SP4(gene name)|psi-mi:SP4(display_short)|uniprotkb:SPR-1(gene name synonym) psi-mi:q75mz5_human(display_long)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:hCG_1813384(orf name) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249420|imex:IM-24135-1075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003103.2|refseq:NP_001313472.1|ensembl:ENSP00000222584|ensembl:ENSG00000105866(gene)|ensembl:ENST00000222584(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030453|interpro:IPR036236|entrezgene/locuslink:6671(identity) ensembl:ENSG00000128573(gene)|ensembl:ENST00000462331(transcript)|entrezgene/locuslink:93986(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:DK4Of4EpByHdtSsZb3eAiOlGFNY9606 rogid:mjDQKtW8rKjWGu5QYC71nlpZOjQ9606 rigid:ki1YjKE4jCNZPUFGkmGO/DNXlrw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49247 uniprotkb:Q75MZ5 intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646 intact:EBI-10255915|ensembl:ENSP00000418100 psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym) psi-mi:q75mz5_human(display_long)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:hCG_1813384(orf name) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249410|imex:IM-24135-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336|entrezgene/locuslink:22934(identity) ensembl:ENSG00000128573(gene)|ensembl:ENST00000462331(transcript)|entrezgene/locuslink:93986(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606 rogid:mjDQKtW8rKjWGu5QYC71nlpZOjQ9606 rigid:bBpKzA7W9hRmLL99BiKEqW416b8 false sufficient binding region:75-311 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96R06 uniprotkb:Q8IXW7 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 intact:EBI-11976595|ensembl:ENSP00000355115|ensembl:ENSP00000477839 psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:q8ixw7_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249402|imex:IM-24135-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity) ensembl:ENSG00000102081(gene)|ensembl:ENST00000334557(transcript)|ensembl:ENST00000621987(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|entrezgene/locuslink:2332(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rogid:m3hxnmCQpyTeLVSaY+W4feoBKjU9606 rigid:t6tPVlS8Gt94FcVVaIrbHqkQbqQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50221 uniprotkb:Q8IXW7 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 intact:EBI-11976595|ensembl:ENSP00000355115|ensembl:ENSP00000477839 psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:q8ixw7_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249394|imex:IM-24135-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity) ensembl:ENSG00000102081(gene)|ensembl:ENST00000334557(transcript)|ensembl:ENST00000621987(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|entrezgene/locuslink:2332(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 rogid:m3hxnmCQpyTeLVSaY+W4feoBKjU9606 rigid:jXKU3XoF1kHGyr6NlUO5oyTEZcw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q0VD86 uniprotkb:Q8IXW7 intact:EBI-6509505|ensembl:ENSP00000458316|ensembl:ENSP00000460673|uniprotkb:Q6J273|uniprotkb:Q6PKN9 intact:EBI-11976595|ensembl:ENSP00000355115|ensembl:ENSP00000477839 psi-mi:inca1_human(display_long)|uniprotkb:INCA1(gene name)|psi-mi:INCA1(display_short)|uniprotkb:Inhibitor of CDK interacting with cyclin A1(gene name synonym)|uniprotkb:HSD45(orf name) psi-mi:q8ixw7_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249386|imex:IM-24135-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR026238|ensembl:ENSG00000196388(gene)|ensembl:ENST00000574617(transcript)|ensembl:ENST00000576820(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0030332"(cyclin binding)|refseq:XP_011522134.1|refseq:NP_001161457.1|refseq:NP_001161458.1|refseq:NP_001161459.1|refseq:NP_998891.2|refseq:XP_005256684.1|refseq:XP_005256685.1|refseq:XP_005256686.1|refseq:XP_006721580.1|refseq:XP_006721581.1|refseq:XP_006721582.1|entrezgene/locuslink:388324(identity) ensembl:ENSG00000102081(gene)|ensembl:ENST00000334557(transcript)|ensembl:ENST00000621987(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|entrezgene/locuslink:2332(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:gN4r3JvEz9V+VYDsBLlhSaDM6Is9606 rogid:m3hxnmCQpyTeLVSaY+W4feoBKjU9606 rigid:WdHg6jMX7cKr2Z2MKTYPB2dV0Uw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:Q8IXW7 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-11976595|ensembl:ENSP00000355115|ensembl:ENSP00000477839 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:q8ixw7_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249378|imex:IM-24135-1245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity) ensembl:ENSG00000102081(gene)|ensembl:ENST00000334557(transcript)|ensembl:ENST00000621987(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|entrezgene/locuslink:2332(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:m3hxnmCQpyTeLVSaY+W4feoBKjU9606 rigid:51d717lE1tYSvrL7+RQn/ylE5fQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A1L4K1 uniprotkb:Q8IXW7 intact:EBI-5661036|uniprotkb:B3KVG1|uniprotkb:B7ZM02|ensembl:ENSP00000335651 intact:EBI-11976595|ensembl:ENSP00000355115|ensembl:ENSP00000477839 psi-mi:fsd2_human(display_long)|uniprotkb:SPRY domain-containing protein 1(gene name synonym)|uniprotkb:SPRYD1(gene name synonym)|uniprotkb:FSD2(gene name)|psi-mi:FSD2(display_short) psi-mi:q8ixw7_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249370|imex:IM-24135-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007123.1|refseq:XP_005272482.1|refseq:NP_001268734.1|refseq:NP_001268735.1|ensembl:ENSG00000186628(gene)|ensembl:ENST00000334574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|entrezgene/locuslink:123722(identity) ensembl:ENSG00000102081(gene)|ensembl:ENST00000334557(transcript)|ensembl:ENST00000621987(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|entrezgene/locuslink:2332(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XD3MwGtfyGillIn2aNaHaiAwEls9606 rogid:m3hxnmCQpyTeLVSaY+W4feoBKjU9606 rigid:lxEaqZVlWIXeDMr3coMU4VW/H6s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:P49789 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249362|imex:IM-24135-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N|entrezgene/locuslink:2272(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606 rigid:7UBUZ5EgpDGNQkBMFz15kdu15HQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49789 uniprotkb:P49789 intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9 intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9 psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym) psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249354|imex:IM-24135-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N|entrezgene/locuslink:2272(identity) refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N|entrezgene/locuslink:2272(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606 rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606 rigid:kt+NHRqoKFIxUA4cKxWDRI2Axh4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8HWS3 uniprotkb:Q92731-3 intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208 intact:EBI-12259414|ensembl:ENSP00000345616 psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym) psi-mi:q92731-3(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym)|uniprotkb:Beta-2A(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249346|imex:IM-24135-1073 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity) intact:EBI-78505(isoform-parent)|uniprotkb:Q92731-3(isoform-parent)|ensembl:ENSG00000140009(gene)|ensembl:ENST00000344288(transcript)|entrezgene/locuslink:2100(identity) - - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606 rogid:4CXi3LzpBKGETEwpH7dKa9pZ/4o9606 rigid:siZliZPKTW/TWDdW5WJ2Xhw0V3A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:Q92731-3 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-12259414|ensembl:ENSP00000345616 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:q92731-3(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym)|uniprotkb:Beta-2A(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249338|imex:IM-24135-1071 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) intact:EBI-78505(isoform-parent)|uniprotkb:Q92731-3(isoform-parent)|ensembl:ENSG00000140009(gene)|ensembl:ENST00000344288(transcript)|entrezgene/locuslink:2100(identity) - - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:4CXi3LzpBKGETEwpH7dKa9pZ/4o9606 rigid:mwLZLkL2XgEDrkSjS4rgzJzXlQw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:Q92731 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249330|imex:IM-24135-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76|entrezgene/locuslink:2100(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rigid:Lk91qGGJOlmfKvajcN0KQAxY6+w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96CN9 uniprotkb:P78347-2 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249532|imex:IM-24135-1249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent)|entrezgene/locuslink:2969(identity) - - isoform-comment:Contains a phosphoserine at position 278. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:dsDez9qsG3+K/tCPHsAPVAPLP9Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:P28222 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-1056863|uniprotkb:Q4VAY7|ensembl:ENSP00000358963 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:5ht1b_human(display_long)|uniprotkb:HTR1B(gene name)|psi-mi:HTR1B(display_short)|uniprotkb:HTR1DB(gene name synonym)|uniprotkb:Serotonin receptor 1B(gene name synonym)|uniprotkb:Serotonin 1D beta receptor(gene name synonym)|uniprotkb:S12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249670|imex:IM-24135-1251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity) refseq:NP_000854.1|ensembl:ENSG00000135312(gene)|ensembl:ENST00000369947(transcript)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014053"(negative regulation of gamma-aminobutyric acid secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014063"(negative regulation of serotonin secretion)|go:"GO:0030425"(dendrite)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0035690"|go:"GO:0042220"(response to cocaine)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042756"(drinking behavior)|go:"GO:0044305"(calyx of Held)|go:"GO:0045471"(response to ethanol)|go:"GO:0046849"(bone remodeling)|go:"GO:0050795"(regulation of behavior)|go:"GO:0051378"(serotonin binding)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0098666"(G protein-coupled serotonin receptor complex)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002147(5-Hydroxytryptamine 1B receptor)|interpro:IPR002231(5-Hydroxytryptamine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2G1X|rcsb pdb:4IAQ|rcsb pdb:4IAR|rcsb pdb:5V54|rcsb pdb:6G79|rcsb pdb:7C61|reactome:R-HSA-390666|reactome:R-HSA-418594|go:"GO:0030594"(neurotransmitter receptor activity)|entrezgene/locuslink:3351(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:KFPTq2aY7OgpBIAdtvUbOX5mnv49606 rigid:K/xal1edzGURNksmYtRXrfT4Bws false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WWW0-2 uniprotkb:P01112 intact:EBI-960502|ensembl:ENSP00000462576 intact:EBI-350145|uniprotkb:Q9BR65|uniprotkb:Q14080|uniprotkb:Q6FHV9|uniprotkb:B5BUA0|uniprotkb:Q9UCE2|ensembl:ENSP00000309845|ensembl:ENSP00000380723|ensembl:ENSP00000407586|ensembl:ENSP00000480686|ensembl:ENSP00000482366|ensembl:ENSP00000488757 psi-mi:q8www0-2(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:RAPL(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym) psi-mi:rash_human(display_long)|uniprotkb:HRAS(gene name)|psi-mi:HRAS(display_short)|uniprotkb:HRAS1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:p21ras(gene name synonym)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:Ha-Ras(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249662|imex:IM-24135-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-367390(q8www0_human)|ensembl:ENSG00000266094(gene)|ensembl:ENST00000577571(transcript)|uniprotkb:Q8WWW0-2(isoform-parent)|entrezgene/locuslink:83593(identity) refseq:NP_001123914.1|refseq:NP_005334.1|refseq:NP_789765.1|ensembl:ENSG00000174775(gene)|ensembl:ENSG00000276536(gene)|ensembl:ENST00000311189(transcript)|ensembl:ENST00000397596(transcript)|ensembl:ENST00000451590(transcript)|ensembl:ENST00000610977(transcript)|ensembl:ENST00000615062(transcript)|ensembl:ENST00000631404(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01112|rcsb pdb:121P|rcsb pdb:1AA9|rcsb pdb:1AGP|rcsb pdb:1BKD|rcsb pdb:1CLU|rcsb pdb:1CRP|rcsb pdb:1CRQ|rcsb pdb:1CRR|rcsb pdb:1CTQ|rcsb pdb:1GNP|rcsb pdb:1GNQ|rcsb pdb:1GNR|rcsb pdb:1HE8|rcsb pdb:1IAQ|rcsb pdb:1IOZ|rcsb pdb:1JAH|rcsb pdb:1JAI|rcsb pdb:1K8R|rcsb pdb:1LF0|rcsb pdb:1LF5|rcsb pdb:1LFD|rcsb pdb:1NVU|rcsb pdb:1NVV|rcsb pdb:1NVW|rcsb pdb:1NVX|rcsb pdb:1P2S|rcsb pdb:1P2T|rcsb pdb:1P2U|rcsb pdb:1P2V|rcsb pdb:1PLJ|rcsb pdb:1PLK|rcsb pdb:1PLL|rcsb pdb:1Q21|rcsb pdb:1QRA|rcsb pdb:1RVD|rcsb pdb:1WQ1|rcsb pdb:1XCM|rcsb pdb:1XD2|rcsb pdb:1XJ0|rcsb pdb:1ZVQ|rcsb pdb:1ZW6|rcsb pdb:221P|rcsb pdb:2C5L|rcsb pdb:2CE2|rcsb pdb:2CL0|rcsb pdb:2CL6|rcsb pdb:2CL7|rcsb pdb:2CLC|rcsb pdb:2CLD|rcsb pdb:2EVW|rcsb pdb:2GDP|rcsb pdb:2LCF|rcsb pdb:2LWI|rcsb pdb:2N42|rcsb pdb:2N46|rcsb pdb:2Q21|rcsb pdb:2QUZ|rcsb pdb:2RGA|rcsb pdb:2RGB|rcsb pdb:2RGC|rcsb pdb:2RGD|rcsb pdb:2RGE|rcsb pdb:2RGG|rcsb pdb:2UZI|rcsb pdb:2VH5|rcsb pdb:2X1V|rcsb pdb:3DDC|rcsb pdb:3I3S|rcsb pdb:3K8Y|rcsb pdb:3K9L|rcsb pdb:3K9N|rcsb pdb:3KKM|rcsb pdb:3KKN|rcsb pdb:3KUD|rcsb pdb:3L8Y|rcsb pdb:3L8Z|rcsb pdb:3LBH|rcsb pdb:3LBI|rcsb pdb:3LBN|rcsb pdb:3LO5|rcsb pdb:3OIU|rcsb pdb:3OIV|rcsb pdb:3OIW|rcsb pdb:3RRY|rcsb pdb:3RRZ|rcsb pdb:3RS0|rcsb pdb:3RS2|rcsb pdb:3RS3|rcsb pdb:3RS4|rcsb pdb:3RS5|rcsb pdb:3RS7|rcsb pdb:3RSL|rcsb pdb:3RSO|rcsb pdb:3TGP|rcsb pdb:421P|rcsb pdb:4DLR|rcsb pdb:4DLS|rcsb pdb:4DLT|rcsb pdb:4DLU|rcsb pdb:4DLV|rcsb pdb:4DLW|rcsb pdb:4DLX|rcsb pdb:4DLY|rcsb pdb:4DLZ|rcsb pdb:4DST|rcsb pdb:4DSU|rcsb pdb:4EFL|rcsb pdb:4EFM|rcsb pdb:4EFN|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4K81|rcsb pdb:4L9S|rcsb pdb:4L9W|rcsb pdb:4NYI|rcsb pdb:4NYJ|rcsb pdb:4NYM|rcsb pdb:4Q21|rcsb pdb:4RSG|rcsb pdb:4URU|rcsb pdb:4URV|rcsb pdb:4URW|rcsb pdb:4URX|rcsb pdb:4URY|rcsb pdb:4URZ|rcsb pdb:4US0|rcsb pdb:4US1|rcsb pdb:4US2|rcsb pdb:4XVQ|rcsb pdb:4XVR|rcsb pdb:521P|rcsb pdb:5B2Z|rcsb pdb:5B30|rcsb pdb:5E95|rcsb pdb:5P21|rcsb pdb:5VBE|rcsb pdb:5VBZ|rcsb pdb:5WDO|rcsb pdb:5WDP|rcsb pdb:5WDQ|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-3928662|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6Q21|rcsb pdb:5WFO|rcsb pdb:5WFP|rcsb pdb:5WFQ|rcsb pdb:5WFR|rcsb pdb:5WPL|rcsb pdb:5X9S|rcsb pdb:5ZC6|rcsb pdb:6V94|rcsb pdb:6V9F|rcsb pdb:6V9J|rcsb pdb:6V9L|rcsb pdb:6V9M|rcsb pdb:621P|rcsb pdb:6AMB|rcsb pdb:6AXG|rcsb pdb:6BVI|rcsb pdb:6BVJ|rcsb pdb:6BVK|rcsb pdb:6BVL|rcsb pdb:6BVM|rcsb pdb:6CUO|rcsb pdb:6CUP|rcsb pdb:6CUR|rcsb pdb:6D55|rcsb pdb:6D56|rcsb pdb:6D59|rcsb pdb:6D5E|rcsb pdb:6D5G|rcsb pdb:6D5H|rcsb pdb:6D5J|rcsb pdb:6D5L|rcsb pdb:6D5M|rcsb pdb:6D5V|rcsb pdb:6D5W|rcsb pdb:6DZH|rcsb pdb:6E6C|rcsb pdb:6E6P|rcsb pdb:6MQT|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|rcsb pdb:6V9N|rcsb pdb:6V9O|rcsb pdb:6ZJ0|rcsb pdb:6ZL3|rcsb pdb:721P|rcsb pdb:7JHP|rcsb pdb:7L0F|rcsb pdb:7L0G|rcsb pdb:821P|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|refseq:NP_001304983.1|dip:DIP-1050N|entrezgene/locuslink:3265(identity) - isoform-comment:Initiator Met-1 is removed. Contains a N-acetylthreonine at position 2. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:zcc13rWLmCPQVfU4D6bvIiAnIbc9606 rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw9606 rigid:8UlpWS2J/UwFxB56vCRP1oeSYdU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:P01892 intact:EBI-16439278 intact:EBI-2839473|uniprotkb:Q9TPY0|uniprotkb:Q29680|uniprotkb:Q29899|uniprotkb:P06338|uniprotkb:P30445|uniprotkb:Q95352|uniprotkb:Q9TQI3|uniprotkb:Q95380|uniprotkb:P30444|uniprotkb:Q9TPX8|uniprotkb:O19619|uniprotkb:P30446|uniprotkb:Q9TQH5|uniprotkb:P10313|uniprotkb:Q9TPX9|uniprotkb:P30514|uniprotkb:Q29837 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:1a02_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*02(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249654|imex:IM-24135-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) rcsb pdb:4MNQ|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5HYJ|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4OV5|rcsb pdb:4UQ3|ensembl:ENSG00000227715|ensembl:ENSP00000448077|ensembl:ENST00000547522|rcsb pdb:5SWQ|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5HHM|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E6I|rcsb pdb:5IRO|rcsb pdb:6D7G|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016567"(protein ubiquitination)|rcsb pdb:5D2L|rcsb pdb:5D2N|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|rcsb pdb:4WJ5|go:"GO:0003723"(RNA binding)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5E00|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:"GO:0031901"(early endosome membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050690"(regulation of defense response to virus by virus)|go:"GO:0060337"(type I interferon signaling pathway)|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0009986"(cell surface)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0046977"(TAP binding)|go:"GO:2000568"(positive regulation of memory T cell activation)|rcsb pdb:3QFD|rcsb pdb:4K7F|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0030670"(phagocytic vesicle membrane)|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:5NMG|rcsb pdb:5NHT|rcsb pdb:5NQK|rcsb pdb:4WUU|rcsb pdb:4E5X|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:4I4W|rcsb pdb:5EOT|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:3TO2|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4EUP|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0042608"(T cell receptor binding)|rcsb pdb:4L3E|ensembl:ENSG00000235657|ensembl:ENSP00000403575|ensembl:ENSP00000447962|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|rcsb pdb:4FTV|rcsb pdb:5E9D|rcsb pdb:5C07|rcsb pdb:5C08|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000457879|ensembl:ENST00000547271|go:"GO:0051290"(protein heterotetramerization)|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5N1Y|go:"GO:0002250"(adaptive immune response)|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:5ENW|reactome:R-HSA-8866654|rcsb pdb:5JZI|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5TEZ|rcsb pdb:5WSH|mint:P01892|rcsb pdb:5N6B|rcsb pdb:5W1W|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0062061"(TAP complex binding)|rcsb pdb:6G3J|entrezgene/locuslink:3105(identity) - - no-uniprot-update:Deprecated HLA-A AC, merged into a different UniProt canonical but we have mutation features in variable positions.|comment:"Allele =A*02:01:01:01"|comment:"Allele =A*02:01:01:01 according to IPD-IMGT/HLA database" figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:oTL0BWZeACoxMc++WgT0XDz+sNg9606 rigid:bVwiaTtS1OB38lRgptCOSZVcEB8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75928-2 uniprotkb:P78347-2 intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249552|imex:IM-24135-875 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent)|entrezgene/locuslink:2969(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562." isoform-comment:Contains a phosphoserine at position 278. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:eRZufenA2aDsQXM/fiuVmkt1FQ8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:P04439 intact:EBI-16439278 intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|ensembl:ENSP00000366005|ensembl:ENSP00000379873|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249591|imex:IM-24135-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) ensembl:ENST00000376809(transcript)|ensembl:ENST00000396634(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|ensembl:ENSG00000206503(gene)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:1P7Q|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MGT|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4GKN|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4I48|rcsb pdb:4WJ5|rcsb pdb:4I4W|rcsb pdb:4WU5|rcsb pdb:4JFD|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:5NME|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0C|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:6EWA|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6RSY|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|refseq:NP_002107.3|refseq:NP_001229687.1|entrezgene/locuslink:3105(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/11/11 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606 rigid:LDz9pc1FmQyIqitVToxDM68zqP0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y4K3 uniprotkb:X5D7Q9 intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16 intact:EBI-21249576 psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym) psi-mi:x5d7q9_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249583|imex:IM-24135-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N|entrezgene/locuslink:7189(identity) go:"GO:0005634"(nucleus)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR036647|entrezgene/locuslink:2969(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606 rogid:l8/OMjhX5l5nULWebTKnpE15mrw9606 rigid:5NfiAh5WlolwxUzHkha+aLCZV0U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14202-3 uniprotkb:P78347-2 intact:EBI-21249560|ensembl:ENSP00000363093 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:q14202-3(display_long)|uniprotkb:ZMYM3(gene name)|psi-mi:ZMYM3(display_short)|uniprotkb:DXS6673E(gene name synonym)|uniprotkb:KIAA0385(gene name synonym)|uniprotkb:ZNF261(gene name synonym)|uniprotkb:Zinc finger protein 261(gene name synonym) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249568|imex:IM-24135-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147130(gene)|ensembl:ENST00000373981(transcript)|intact:EBI-2556139(isoform-parent)|entrezgene/locuslink:9203(identity) ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent)|entrezgene/locuslink:2969(identity) - - isoform-comment:Contains a phosphoserine at position 278. figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SjryiyIbuSmry59hIUOs4NVhQV89606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:7LdVuSyiZFkdeOMmT5Z9JNz9uPU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:P04439 intact:EBI-16439278 intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|ensembl:ENSP00000366005|ensembl:ENSP00000379873|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249646|imex:IM-24135-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) ensembl:ENST00000376809(transcript)|ensembl:ENST00000396634(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|ensembl:ENSG00000206503(gene)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:1P7Q|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MGT|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4GKN|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4I48|rcsb pdb:4WJ5|rcsb pdb:4I4W|rcsb pdb:4WU5|rcsb pdb:4JFD|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:5NME|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0C|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:6EWA|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6RSY|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|refseq:NP_002107.3|refseq:NP_001229687.1|entrezgene/locuslink:3105(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/11/11 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606 rigid:LDz9pc1FmQyIqitVToxDM68zqP0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJX2 uniprotkb:P27361 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250036|imex:IM-24135-893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:VUxtcCMr3L7WgYE5/ClS+ZF+sew false sufficient binding region:7-597 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A2BDD9 uniprotkb:P27361 intact:EBI-17286414 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:a2bdd9_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250028|imex:IM-24135-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009114(Angiomotin)|interpro:IPR024646|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:154796(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V7QDsb53M7GgkKnEOQV3aYalCBc9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:0i3tG6w1wR08tIiOyiBSVP0v74Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D2L7 intact:EBI-21247765 intact:EBI-21249998 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d2l7_human(display_long)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250020|imex:IM-24135-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:1990939"|interpro:IPR027640|interpro:IPR001752(Kinesin, motor region)|interpro:IPR036961|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:eQKNzGcTVN6BRR7Ur9Ba3VkH0Uo9606 rigid:xOQNFMZ/cTSjLe+2N8Z9pLgkcfk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-21247090 uniprotkb:X5D2L7 - intact:EBI-21249998 psi-mi:ar(display_short)|psi-mi:EBI-21247090(display_long) psi-mi:x5d2l7_human(display_long)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250012|imex:IM-24135-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:367(identity) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:1990939"|interpro:IPR027640|interpro:IPR001752(Kinesin, motor region)|interpro:IPR036961|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wvdZkJPqNLB1OI88kaK8MSi4FoI9606 rogid:eQKNzGcTVN6BRR7Ur9Ba3VkH0Uo9606 rigid:Agn3RfaS0WboF4JJaEAkyxwB6x0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:Q12756 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249990|imex:IM-24135-1261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:1L++TCpWnOBjbPwWNfqMmZy2XPQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:Q12756 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249982|imex:IM-24135-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:2Ry4pBD/mn29XjsIuZjGo2QB1/w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13077 uniprotkb:Q12756 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249974|imex:IM-24135-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|entrezgene/locuslink:7185(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:risYlZAiIqp50boyyP7yBPdHKLg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63HR2 uniprotkb:Q12756 intact:EBI-949753|ensembl:ENSP00000319684|uniprotkb:A2VDF2|uniprotkb:A2VDF3|uniprotkb:A2VDI8|uniprotkb:Q2NL80|uniprotkb:Q76MW6|uniprotkb:Q7Z5T9|uniprotkb:Q8NFF9|uniprotkb:Q8NFG0|uniprotkb:Q96P25|uniprotkb:Q9NT29|uniprotkb:Q9UPS7|uniprotkb:A5PKY4 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:tns2_human(display_long)|uniprotkb:TNS2(gene name)|psi-mi:TNS2(display_short)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:KIAA1075(gene name synonym)|uniprotkb:TENC1(gene name synonym)|uniprotkb:Tensin-like C1 domain-containing phosphatase(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249964|imex:IM-24135-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000314250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019900"(kinase binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048871"(multicellular organismal homeostasis)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|mint:Q63HR2|rcsb pdb:2DKQ|rcsb pdb:2KNO|rcsb pdb:2L6K|rcsb pdb:2LOZ|rcsb pdb:3HQC|ensembl:ENSG00000111077(gene)|refseq:NP_056134.2|refseq:NP_736610.2|refseq:NP_938072.1|entrezgene/locuslink:23371(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:uobqTi6g78V5Iib3uRGGhqjSt7o9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:rpgR1XmeQrtmOMlVl0zPFTYZhSk false sufficient binding region:125-1409 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43597 uniprotkb:Q12756 intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249956|imex:IM-24135-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:u1omauzisc6MdZlogMotUmtauSI9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:/2L7PKEYjftpIlaYRJ4EHZdwrjg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EP0 uniprotkb:Q12756 intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249946|imex:IM-24135-1259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN|entrezgene/locuslink:55072(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:5QylozByg2G8/5LnkorkdY5fPec9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:fkonuYE1pAf+VX84vFSRP5bmmvw false sufficient binding region:484-1072 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76081-6 uniprotkb:Q12756 intact:EBI-10178530|ensembl:ENSP00000276500 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249938|imex:IM-24135-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)|entrezgene/locuslink:8601(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:I4sJRRzHD/9Tmkgz4d6k0hmMyEk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8HWS3 uniprotkb:Q12756 intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249930|imex:IM-24135-1257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:bzrkAhrW9EeIfFkjRrkW5/LhOU4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:Q12756 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249922|imex:IM-24135-1255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:udDSkfsMqqcw1WutUoAv3md8Csk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:Q12756 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249914|imex:IM-24135-1085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:I/dI8cb38mvPyWAEE6VPz3gJBhA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:Q12756 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249906|imex:IM-24135-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:YrG/NLrS9jSSggt9LgchCmaHN80 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3S9 uniprotkb:Q12756 intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249898|imex:IM-24135-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:0ZxToeGcxqA0+Ju+JZKOTxBvfZk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:Q12756 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249890|imex:IM-24135-891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:vjxCe1k5Y+0bsEfnYZ1+2SNCDcE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13064 uniprotkb:Q12756 intact:EBI-2340269|ensembl:ENSP00000313881 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249882|imex:IM-24135-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064|entrezgene/locuslink:7681(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:ZCuo/snBmNjT7kiCWGJ9xuS+PfM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJV3-2 uniprotkb:Q12756 intact:EBI-10172526|ensembl:ENSP00000413976 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249872|imex:IM-24135-889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:mVZXsHNkbKbDlmPqkpXL6Cw8+RI false sufficient binding region:21-705 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q12756 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249864|imex:IM-24135-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:g0LMqHmDhcZwnI4BWlWRKCqhDq0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:Q12756 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249856|imex:IM-24135-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:jojERW4Wh9OhWR2hVtwmqcdH5g0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14-3 uniprotkb:Q12756 intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249846|imex:IM-24135-887 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR|entrezgene/locuslink:547(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:Jt8hNkGOt/6ELZjlFzvYLq4y/eg false sufficient binding region:674-1097 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6PF05 uniprotkb:Q6IPM2 intact:EBI-8656864|ensembl:ENSP00000422188|uniprotkb:Q96LJ2|intact:MINT-8163808|uniprotkb:Q6RGS4|uniprotkb:Q8N7R3|uniprotkb:G8IJH6 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:tt23l_human(display_long)|uniprotkb:TTC23L(gene name)|psi-mi:TTC23L(display_short) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249838|imex:IM-24135-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000205838(gene)|ensembl:ENST00000505624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042621|mint:Q6PF05|refseq:NP_001304878.1|refseq:NP_653326.3|entrezgene/locuslink:153657(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SRndoUysST7RgIovvs89vd30vMk9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:QoD7PUL/zrTh2hDaSU88oXAlBSs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:Q6IPM2 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249830|imex:IM-24135-885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:7lqqa1ehsdQlv6T1Kjh+yi8aV94 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:Q6IPM2 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249822|imex:IM-24135-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:UETYRIqcgVlJX8kqjGDpigZBsWY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96R06 uniprotkb:Q6IPM2 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249814|imex:IM-24135-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N|entrezgene/locuslink:10615(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:CAlKD8oUktXE3bvGOT3NKi+onCM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96KN7-4 uniprotkb:Q6IPM2 intact:EBI-11525164|ensembl:ENSP00000372391 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249806|imex:IM-24135-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:meK5zQiXoNtqL5hR2c2d0Ay5LCw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:Q6IPM2 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249798|imex:IM-24135-883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:uQkreVMAeDNk+QWQZXHUOTbzBdI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:Q6IPM2 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249790|imex:IM-24135-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:V9V6g8MTxb4GIEtsJ/MOsmoCfEE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:Q6IPM2 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249782|imex:IM-24135-1253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:AL31Nf03TCgQTzcs7fVpAWhP4h0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96ED9-2 uniprotkb:Q6IPM2 intact:EBI-10961706|ensembl:ENSP00000264827 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249774|imex:IM-24135-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:52BXgrOLbzyWyzD3qSB9YxCs9d4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:Q6IPM2 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249764|imex:IM-24135-881 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:tXJxxIrkvlkkcqmBvsWj9LkqEmA false sufficient binding region:383-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NHQ1 uniprotkb:Q6IPM2 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249756|imex:IM-24135-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:xeCQO+Dv1NcxDyMXaD68kaZVm4A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H257-3 uniprotkb:Q6IPM2 intact:EBI-16431743|ensembl:ENSP00000451368 intact:EBI-3893098|uniprotkb:Q4G0P7|uniprotkb:Q6P7T4|uniprotkb:Q9H0H7|uniprotkb:Q9UPX7|intact:EBI-28974955|ensembl:ENSP00000385597 psi-mi:q9h257-3(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short) psi-mi:iqce_human(display_long)|uniprotkb:IQCE(gene name)|psi-mi:IQCE(display_short)|uniprotkb:KIAA1023(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249748|imex:IM-24135-879 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-751319(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000489932(transcript)|uniprotkb:Q9H257-3(isoform-parent)|entrezgene/locuslink:64170(identity) ensembl:ENST00000325979|ensembl:ENSP00000313772|ensembl:ENSP00000385597|ensembl:ENST00000404984|ensembl:ENSP00000385945|ensembl:ENST00000438376|ensembl:ENSP00000396178|ensembl:ENST00000623361|ensembl:ENSP00000485601|refseq:NP_689771.3|refseq:NP_001274430.1|ensembl:ENSG00000106012(gene)|go:"GO:0005929"(cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0060170"(ciliary membrane)|interpro:IPR000048(IQ calmodulin-binding region)|reactome:R-HSA-5635838|ensembl:ENST00000402050(transcript)|entrezgene/locuslink:23288(identity) - isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8ZrBhVHfPbIFpll5feiFDiUdyYs9606 rogid:m4KgBxDPtL8805egisj58bzd+089606 rigid:IPs+kcBseVwhI2jIT4fjKGOilPY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6Y0 uniprotkb:X5DP77 intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597 intact:EBI-21249678 psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249740|imex:IM-24135-1083 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:RDmR/qkEn178Fs7cdYNWKwL2pnA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P20393 uniprotkb:X5DP77 intact:EBI-2811738|uniprotkb:Q15304|uniprotkb:Q0P5Z4|ensembl:ENSP00000246672 intact:EBI-21249678 psi-mi:nr1d1_human(display_long)|uniprotkb:NR1D1(gene name)|psi-mi:NR1D1(display_short)|uniprotkb:EAR1(gene name synonym)|uniprotkb:HREV(gene name synonym)|uniprotkb:THRAL(gene name synonym)|uniprotkb:Rev-erbA-alpha(gene name synonym)|uniprotkb:V-erbA-related protein 1(gene name synonym) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249732|imex:IM-24135-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068370.1|ensembl:ENSG00000126368(gene)|ensembl:ENST00000246672(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043197"(dendritic spine)|go:"GO:0044321"(response to leptin)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0061889"(negative regulation of astrocyte activation)|go:"GO:0070859"(positive regulation of bile acid biosynthetic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0150079"(negative regulation of neuroinflammatory response)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1A6Y|rcsb pdb:1EF6|rcsb pdb:1GA5|rcsb pdb:1HLZ|rcsb pdb:3N00|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-48396N|entrezgene/locuslink:9572(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:UfaVQzUQ3wD4xDBh1sjp+eaawY89606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:2Ms/oj6r5TSLfjdTonHoM57OkwM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z6G3-2 uniprotkb:X5DP77 intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040 intact:EBI-21249678 psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249722|imex:IM-24135-1081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:i1+2cPd2TOqKjPEO+mtCZSWYUXo false sufficient binding region:65-303 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14777 uniprotkb:X5DP77 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-21249678 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249714|imex:IM-24135-877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N|entrezgene/locuslink:10403(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:3TgahdqN9uidfyQMiOcTXdeL2xg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DP77 intact:EBI-16439278 intact:EBI-21249678 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249706|imex:IM-24135-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:cePl7zn+J7KbusqAP/teJOeqCuc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:X5DP77 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-21249678 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249698|imex:IM-24135-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:tud2LusCHhwlowIYMd7fm6Qd2B0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUW7 uniprotkb:X5DP77 intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085 intact:EBI-21249678 psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249690|imex:IM-24135-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)|entrezgene/locuslink:79095(identity) entrezgene/locuslink:3628(identity) - crc64:EBE1D0AFAAD6DABB - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:CrrNxgGt6yWd5jkm0qTkR+R0J6E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A1L190 uniprotkb:X5DP77 intact:EBI-10283466|intact:EBI-28983485|ensembl:ENSP00000385122|ensembl:ENSP00000385480 intact:EBI-21249678 psi-mi:syce3_human(display_long)|uniprotkb:SYCE3(gene name)|psi-mi:SYCE3(display_short)|uniprotkb:C22orf41(gene name synonym)|uniprotkb:THEG2(gene name synonym)|uniprotkb:Testis highly expressed gene 2 protein(gene name synonym) psi-mi:x5dp77_human(display_long)|uniprotkb:INPP1(gene name)|psi-mi:INPP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21249682|imex:IM-24135-1079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000385122|ensembl:ENSP00000385480|refseq:NP_001116697.1|ensembl:ENSG00000217442(gene)|ensembl:ENST00000402753(transcript)|ensembl:ENST00000406915(transcript)|go:"GO:0000801"(central element)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007283"(spermatogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051301"(cell division)|interpro:IPR028145|reactome:R-HSA-1221632|entrezgene/locuslink:644186(identity) entrezgene/locuslink:3628(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:KbBkFQ5TohktCXAqJ7Nh2dR/Sf49606 rogid:zeofshvnzrjM5Ix87cIr8SaXars9606 rigid:3btKED5vKiCjVYY0ocwTSM+TOhI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYV2 uniprotkb:P27361 intact:EBI-2130429|uniprotkb:A5D8T7|uniprotkb:Q53SY4|uniprotkb:Q9BYV3|ensembl:ENSP00000369415 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:tri54_human(display_long)|uniprotkb:TRIM54(gene name)|psi-mi:TRIM54(display_short)|uniprotkb:MURF(gene name synonym)|uniprotkb:MURF3(gene name synonym)|uniprotkb:RNF30(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 3(gene name synonym)|uniprotkb:Muscle-specific RING finger protein(gene name synonym)|uniprotkb:RING finger protein 30(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250107|imex:IM-24135-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115935.3|refseq:NP_912730.2|interpro:IPR027370|interpro:IPR033492|interpro:IPR042752|rcsb pdb:3Q1D|ensembl:ENSG00000138100(gene)|ensembl:ENST00000380075(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|entrezgene/locuslink:57159(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:rxNKa4ddkMuN1HQlCnhYo2Ypi589606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:MrfTb1NK4p4lqUEWRp6zl73gn9o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15742 uniprotkb:P27361 intact:EBI-8641936|intact:EBI-28986032|ensembl:ENSP00000300131|uniprotkb:Q14797|uniprotkb:O76006|uniprotkb:B2RAK3|intact:MINT-8163249 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:nab2_human(display_long)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)|uniprotkb:EGR-1-binding protein 2(gene name synonym)|uniprotkb:MADER(gene name synonym)|uniprotkb:Melanoma-associated delayed early response protein(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250099|imex:IM-24135-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166886(gene)|ensembl:ENST00000300131(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038398|interpro:IPR039040|mint:Q15742|reactome:R-HSA-9031628|reactome:R-HSA-9619665|ensembl:ENSP00000300131|ensembl:ENST00000342556|ensembl:ENSP00000341491|refseq:NP_005958.1|refseq:NP_001317234.1|entrezgene/locuslink:4665(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vj6P9S6D3S72qXfd7K7X5gC9bGI9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:embwCNTZkGPhZpzzjjIrV0kafrA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15173 uniprotkb:P27361 intact:EBI-3906629|uniprotkb:Q53XW6|ensembl:ENSP00000241651 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:myog_human(display_long)|uniprotkb:MYOG(gene name)|psi-mi:MYOG(display_short)|uniprotkb:BHLHC3(gene name synonym)|uniprotkb:MYF4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Myogenic factor 4(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250091|imex:IM-24135-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002470.2|ensembl:ENSG00000122180(gene)|ensembl:ENST00000241651(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009629"(response to gravity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0071259"(cellular response to magnetism)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|dip:DIP-159N|entrezgene/locuslink:4656(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7r8zPLBvho1GRHTAr7SVXjDXRxg9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:Amk+0rwlLUXUaQJ/QzQGE+qiwQY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y5V3 uniprotkb:P27361 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250083|imex:IM-24135-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:ZLPe66yTMNHOEPQPmBPb02b6/BE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N1B4 uniprotkb:P27361 intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250115|imex:IM-24135-897 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:dmLWWqdooDJsTS0WyC6aEcAojd8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15409 uniprotkb:P27361 intact:EBI-983612|uniprotkb:A0AUV6|uniprotkb:A4D0U8|uniprotkb:Q6ZND1|uniprotkb:Q75MJ3|uniprotkb:Q8IZE0|uniprotkb:Q8N0W2|uniprotkb:Q8N6B7|uniprotkb:Q8N6B8|uniprotkb:Q8NFQ1|uniprotkb:Q8NFQ2|uniprotkb:Q8NFQ3|uniprotkb:Q8NFQ4|uniprotkb:Q8TD74|ensembl:ENSP00000265436|ensembl:ENSP00000377132|uniprotkb:A6NNW4|uniprotkb:B4DLD9 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:foxp2_human(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250065|imex:IM-24135-895 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128573(gene)|ensembl:ENST00000350908(transcript)|ensembl:ENST00000393494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021757"(caudate nucleus development)|go:"GO:0021758"(putamen development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0098582"(innate vocalization behavior)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:O15409|rcsb pdb:2A07|rcsb pdb:2AS5|go:"GO:0046872"(metal ion binding)|refseq:NP_001166237.1|refseq:NP_001166238.1|refseq:NP_055306.1|refseq:NP_683696.2|refseq:NP_683697.2|refseq:NP_683698.2|dip:DIP-29004N|refseq:XP_016868290.1|entrezgene/locuslink:93986(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XRN9auLs2qtK6W3mjHJHAQPbO9s9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:pqanBAE0tAAtJF+j8Yr8YmF8p3k false sufficient binding region:93-715 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49366 uniprotkb:P27361 intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250057|imex:IM-24135-1087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1|entrezgene/locuslink:1725(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:6a543W3C6d0mBuAj+DUlaXr8ZgA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NPI6 uniprotkb:P27361 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250049|imex:IM-24135-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N|entrezgene/locuslink:55802(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:dHJ9f5HeAu50Azw1ZihVt5U57+c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q68D86 uniprotkb:X5D2M4 intact:EBI-10171570|intact:EBI-11142258|uniprotkb:A1A4H1|uniprotkb:Q7Z467|uniprotkb:Q8NDK7|uniprotkb:Q9H5C1|ensembl:ENSP00000353377 intact:EBI-21250123 psi-mi:c102b_human(display_long)|uniprotkb:C18orf14(gene name synonym)|uniprotkb:CCDC102B(gene name)|psi-mi:CCDC102B(display_short) psi-mi:x5d2m4_human(display_long)|uniprotkb:MARK1(gene name)|psi-mi:MARK1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250141|imex:IM-24135-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079057.2|refseq:XP_016881464.1|refseq:NP_001087198.1|ensembl:ENSG00000150636(gene)|ensembl:ENST00000360242(transcript)|entrezgene/locuslink:79839(identity) go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0030425"(dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:XP_005273191.1|interpro:IPR028375|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR033627|entrezgene/locuslink:4139(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:bHcwqAao2a3NfUDSpB2PCaCbHt89606 rogid:8n9S3Duhysgl1774NnzLKRalQtI9606 rigid:MmWtpfMnRc0D0S7YchXK1o8W+Hk false sufficient binding region:217-513 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96JM7-2 uniprotkb:P27361 intact:EBI-11985629|ensembl:ENSP00000357121|ensembl:ENSP00000436706|ensembl:ENSP00000437185 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:q96jm7-2(display_long)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:MBT1(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250075|imex:IM-24135-1263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q96JM7-2(isoform-parent)|ensembl:ENSG00000198945(gene)|ensembl:ENST00000368139(transcript)|ensembl:ENST00000526019(transcript)|ensembl:ENST00000533560(transcript)|intact:EBI-2686809(isoform-parent)|entrezgene/locuslink:84456(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kyV/W+LGXQyvpNVA8XqVS88scjg9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:Mn+61Nfo8xSQZ0KUg+fMwnVGri0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:X5D7R7 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-21250265 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250537|imex:IM-24135-715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:l6XEf8kL53Qb7WIfN02TWgvggFU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q68D86 uniprotkb:X5DNR8 intact:EBI-10171570|intact:EBI-11142258|uniprotkb:A1A4H1|uniprotkb:Q7Z467|uniprotkb:Q8NDK7|uniprotkb:Q9H5C1|ensembl:ENSP00000353377 intact:EBI-21250151 psi-mi:c102b_human(display_long)|uniprotkb:C18orf14(gene name synonym)|uniprotkb:CCDC102B(gene name)|psi-mi:CCDC102B(display_short) psi-mi:x5dnr8_human(display_long)|uniprotkb:MARK1(gene name)|psi-mi:MARK1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250168|imex:IM-24135-1089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079057.2|refseq:XP_016881464.1|refseq:NP_001087198.1|ensembl:ENSG00000150636(gene)|ensembl:ENST00000360242(transcript)|entrezgene/locuslink:79839(identity) go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0030425"(dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR028375|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR033627|entrezgene/locuslink:4139(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:bHcwqAao2a3NfUDSpB2PCaCbHt89606 rogid:XRYUjGK81t3qL8Ahhn9sA9EVKSo9606 rigid:kpMx4XE0MDXLmwzJCZtcTQsL5B4 false sufficient binding region:217-513 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15884-3 uniprotkb:X5D7R7 intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670 intact:EBI-21250265 psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250521|imex:IM-24135-1275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:+JED2wSjoPG6ZntoKPCzuj4jFps false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12757 uniprotkb:X5D7R7 intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119|ensembl:ENSP00000415243 intact:EBI-21250265 psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250513|imex:IM-24135-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|ensembl:ENSG00000136603(gene)|ensembl:ENST00000259119(transcript)|ensembl:ENST00000458537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016605"(PML body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070848"(response to growth factor)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028373|interpro:IPR037000|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|refseq:XP_006713798.1|dip:DIP-42138N|entrezgene/locuslink:6498(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:0WBMNmtRoKuGN6UJmsp/zqC+uNA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHV2 uniprotkb:X5D7R7 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 intact:EBI-21250265 psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250505|imex:IM-24135-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:40dvjniwxY/UQiyoVREicctpWe09606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:x9UWA5qR9UEJa3JfV/JTVXrwlqI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11953272 uniprotkb:X5D7R7 - intact:EBI-21250265 psi-mi:rnf111(display_short)|psi-mi:EBI-11953272(display_long) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250497|imex:IM-24135-1273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:54778(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V6Dzr4m6Ez2P3TbBAdJXsuRzJ7w9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:cdGX3ZWhye23fNOt5JGqsB81FKc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UFD9 uniprotkb:X5D7R7 intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386 intact:EBI-21250265 psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250489|imex:IM-24135-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:HBcqRyyZMk4xbhqZkR+WMAX+LcY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5D7R7 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21250265 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250481|imex:IM-24135-1271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:ZrqL8pjd2VFhzED3jV2/9/ggbUs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:X5D7R7 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-21250265 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250473|imex:IM-24135-1269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:Bu9oedcnl4Cc5C66NlbAtcuClWk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96QF0-7 uniprotkb:X5D7R7 intact:EBI-11984839|ensembl:ENSP00000368092 intact:EBI-21250265 psi-mi:q96qf0-7(display_long)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250465|imex:IM-24135-1267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q96QF0-7(isoform-parent)|intact:EBI-747844(isoform-parent)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000378815(transcript)|entrezgene/locuslink:117177(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:AbUJj24KJUXc9MOj/FSx+ogmdfI9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:Wt2cwAf666+PkvL7tPCjSdQI5iM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43586 uniprotkb:X5D7R7 intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746 intact:EBI-21250265 psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250457|imex:IM-24135-713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:+SsUcsKiuTsemotym0T1yyQcYPQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:X5D7R7 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-21250265 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250449|imex:IM-24135-1097 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:dLLRnRB5LhsxHRS7CumzT4DWm1k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WWB5 uniprotkb:X5D7R7 intact:EBI-10232538|uniprotkb:B4DU48|uniprotkb:E9PD82|ensembl:ENSP00000280350|ensembl:ENSP00000431841|ensembl:ENSP00000503801 intact:EBI-21250265 psi-mi:pihd2_human(display_long)|uniprotkb:PIH1D2(gene name)|psi-mi:PIH1D2(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250441|imex:IM-24135-913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076088.1|refseq:NP_620144.1|interpro:IPR041442|ensembl:ENSG00000150773(gene)|ensembl:ENST00000280350(transcript)|ensembl:ENST00000532211(transcript)|ensembl:ENST00000676994(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0031267"(small GTPase binding)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|entrezgene/locuslink:120379(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:pS1t2OxPhz/jSO5/lveq5x3Ykis9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:sn4a/xeQNje3XQEAedcNvXBHQb8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3S9 uniprotkb:X5D7R7 intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929 intact:EBI-21250265 psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250433|imex:IM-24135-911 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:UmWlOA5ZaSUHkxMJvAei8Z7LySE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A4FUJ8 uniprotkb:X5D7R7 intact:EBI-21250407 intact:EBI-21250265 psi-mi:a4fuj8_human(display_long)|uniprotkb:MKL1(gene name)|psi-mi:MKL1(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250425|imex:IM-24135-711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001269589.1|refseq:NP_001269590.1|refseq:NP_001269591.1|refseq:NP_001305068.1|refseq:NP_065882.1|interpro:IPR029992|interpro:IPR004018(RPEL repeat)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361|interpro:IPR043451|entrezgene/locuslink:57591(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vFOrNpvxSZD6ZkvDc0E/2W0woNg9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:7NxfC+3g5PnhMA1xsSN3uXKW0Tw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJV3-2 uniprotkb:X5D7R7 intact:EBI-10172526|ensembl:ENSP00000413976 intact:EBI-21250265 psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250399|imex:IM-24135-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:Y+/SG87pnsq5Jq3rQFGrY8A//ik false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D7R7 intact:EBI-16439278 intact:EBI-21250265 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250391|imex:IM-24135-1095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:1rl4vVF/1LSxW6p1l4xkeqXmRYY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50221 uniprotkb:X5D7R7 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 intact:EBI-21250265 psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250383|imex:IM-24135-1093 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:yExp0DnL4GEeJEjdyl2KZ96fp0o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:X5D7R7 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-21250265 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250375|imex:IM-24135-709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:F4pI7ZLD806hEH9RAYsEhdyVaas false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O00505 uniprotkb:X5D7R7 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 intact:EBI-21250265 psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250367|imex:IM-24135-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|entrezgene/locuslink:3839(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:Zc6j8X3U/Fs9vWfmK7+R2OdrTDY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7L273 uniprotkb:X5D7R7 intact:EBI-4397613|uniprotkb:Q6NUM8|uniprotkb:Q9NXV4|ensembl:ENSP00000221200 intact:EBI-21250265 psi-mi:kctd9_human(display_long)|uniprotkb:KCTD9(gene name)|psi-mi:KCTD9(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250359|imex:IM-24135-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060104.2|ensembl:ENSG00000104756(gene)|ensembl:ENST00000221200(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR021789|interpro:IPR036572|mint:Q7L273|rcsb pdb:5BXH|entrezgene/locuslink:54793(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:coM0kMYFDztNUR3W7/LsLlFMNXg9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:bWG2euTM+9h1mIB7kEkLNuKeXr8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:X5D7R7 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-21250265 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250351|imex:IM-24135-909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:LvWgqwz+XjRt7OMUUPqC7rPOxh8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VWP2 uniprotkb:X5D7R7 intact:EBI-741787|uniprotkb:A3KMG2|uniprotkb:Q8NE25|uniprotkb:Q9NXK0|ensembl:ENSP00000358458 intact:EBI-21250265 psi-mi:tet5c_human(display_long)|uniprotkb:TENT5C(gene name)|psi-mi:TENT5C(display_short)|uniprotkb:FAM46C(gene name synonym)|uniprotkb:"Non-canonical poly(A) polymerase FAM46C"(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250343|imex:IM-24135-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060179.2|ensembl:ENSG00000183508(gene)|ensembl:ENST00000369448(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0048255"(mRNA stabilization)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR012937(Protein of unknown function DUF1693)|rcsb pdb:6W36|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|entrezgene/locuslink:54855(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Vx+IPZCDUOhOxZF7s1pu2XTLTYs9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:pADu+GZ7YQGLfhrX8L/m5v/ag48 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYX7 uniprotkb:X5D7R7 intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58 intact:EBI-21250265 psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250335|imex:IM-24135-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:vVjw63mcVp3yasl66LNxb4+yaoU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5D7R7 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21250265 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250327|imex:IM-24135-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:wpRFy6Ysgx0f166baJHFpyBbXMA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRI5-2 uniprotkb:X5D7R7 intact:EBI-11988027|ensembl:ENSP00000355597 intact:EBI-21250265 psi-mi:q9nri5-2(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)|uniprotkb:LV(isoform synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250319|imex:IM-24135-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-529989(isoform-parent)|ensembl:ENSG00000162946(gene)|ensembl:ENST00000366637(transcript)|uniprotkb:Q9NRI5-2(isoform-parent)|entrezgene/locuslink:27185(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - isoform-comment:Non-canonical donor and acceptor splice sites for the last 2 exons. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XO2u/5sOZAkkn12A+INm5SA4jUY9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:prFkwOp8XXqGiNa0yv2jVS7K1P0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYA8 uniprotkb:X5D7R7 intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9 intact:EBI-21250265 psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250311|imex:IM-24135-907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:FDypZY18uXADg26WRX30NZlZcyo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:X5D7R7 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-21250265 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250303|imex:IM-24135-905 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:84jFmwAPo51LpAjb9TLDKmUE+SA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D7R7 intact:EBI-21247765 intact:EBI-21250265 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250295|imex:IM-24135-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:4ZpbabKZ0awTWxIhD7cO6EbiXA8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N9N5-2 uniprotkb:X5D7R7 intact:EBI-11524452|ensembl:ENSP00000347125 intact:EBI-21250265 psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250287|imex:IM-24135-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:yVT9+YVqXaobQPcL1c/e/+Eu+nE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08117-2 uniprotkb:X5D7R7 intact:EBI-11741437|ensembl:ENSP00000221561 intact:EBI-21250265 psi-mi:q08117-2(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)|uniprotkb:AES-2(isoform synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250279|imex:IM-24135-1091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104964(gene)|ensembl:ENST00000221561(transcript)|uniprotkb:Q08117-2(isoform-parent)|intact:EBI-717810(isoform-parent)|entrezgene/locuslink:166(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Nrb311r8NRqcGyEJkPxvyjbpt6E9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:96YiEgUsmcREO8GW7sm0BWSsbu0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14-3 uniprotkb:X5D7R7 intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295 intact:EBI-21250265 psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250271|imex:IM-24135-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:c75W+2aG05VntrWg71J27GT9TMs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D7K9 intact:EBI-16439278 intact:EBI-21250249 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d7k9_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250257|imex:IM-24135-903 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036013|refseq:NP_001280134.1|interpro:IPR039059|interpro:IPR021870|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:YCdzfEJrXTiEna2ZV3AMOcAD2zg9606 rigid:wkIINTMMmRaAM5hRNYli+BP/iO8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14764 uniprotkb:Q14764 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250241|imex:IM-24135-707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|entrezgene/locuslink:9961(identity) ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rigid:U6wSPotNf2g4sQeZgORK4QHoryY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q14764 intact:EBI-16439278 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250233|imex:IM-24135-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rigid:rCu4ZpX01sJ0n1SorekpeGlu5gw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DRD0 intact:EBI-16439278 intact:EBI-21250218 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5drd0_human(display_long)|uniprotkb:MTMR10(gene name)|psi-mi:MTMR10(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250225|imex:IM-24135-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030573|interpro:IPR036004|interpro:IPR030564|entrezgene/locuslink:54893(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:Odz8hWh1wjZzqCsOJpf7kLUP5jU9606 rigid:mXIYzfVS+tQ7M/KQfkVK1wSpclw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DR33 intact:EBI-16439278 intact:EBI-21250203 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dr33_human(display_long)|uniprotkb:MTMR10(gene name)|psi-mi:MTMR10(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250210|imex:IM-24135-1265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030573|interpro:IPR036004|interpro:IPR030564|entrezgene/locuslink:54893(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:151oSoOo6nMhgSPqaZw/PvcF+BU9606 rigid:zVnzVrJlcBiBppsTFtpqb/lwaoo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q9NXD2 intact:EBI-16439278 intact:EBI-2829532|uniprotkb:Q6P4Q6|ensembl:ENSP00000402537|ensembl:ENSP00000484437 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:mtmra_human(display_long)|uniprotkb:MTMR10(gene name)|psi-mi:MTMR10(display_short)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 10(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250195|imex:IM-24135-901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_060232.2|ensembl:ENSG00000166912(gene)|ensembl:ENSG00000277086(gene)|ensembl:ENST00000435680(transcript)|ensembl:ENST00000621195(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022587|interpro:IPR029021|interpro:IPR030564|interpro:IPR030573|interpro:IPR036004|mint:Q9NXD2|reactome:R-HSA-1660516|entrezgene/locuslink:54893(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:Rmg98bSIwX+Hg6BceOx/Z0NdXJE9606 rigid:dQSjwJkmI+bPxkeL/ynZipb3/X4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D300 intact:EBI-16439278 intact:EBI-21250178 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d300_human(display_long)|uniprotkb:MTMR10(gene name)|psi-mi:MTMR10(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250187|imex:IM-24135-899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030573|interpro:IPR036004|interpro:IPR010569(Myotubularin-related)|interpro:IPR030564|interpro:IPR029021|entrezgene/locuslink:54893(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:5Vir2M4OrgtfvxiHKXYzgz0KF1k9606 rigid:mw8mDNrbhZ+Sr7nF+G4s8ihwtIE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04637 uniprotkb:X5D7R7 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 intact:EBI-21250265 psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250529|imex:IM-24135-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:HKmVAvOO3HV6nSQN/O4aHBOCxv8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:X5D7R7 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-21250265 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250545|imex:IM-24135-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:kUv0SQ62t0FZLkN0u/dkJuqgtdE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-21247090 uniprotkb:X5DP35 - intact:EBI-21249101 psi-mi:ar(display_short)|psi-mi:EBI-21247090(display_long) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250721|imex:IM-24135-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:367(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wvdZkJPqNLB1OI88kaK8MSi4FoI9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:F38YeSey6LVqrtQJTjXv0TTfayc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5DP35 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21249101 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250729|imex:IM-24135-921 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:9T4A+ahOpfVgsp0iP4Y8XiS5Edg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08AM6 uniprotkb:X5DP17 intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776 intact:EBI-21250593 psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250705|imex:IM-24135-1103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|entrezgene/locuslink:55697(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:gDAkYfH0gDNv+jyuhGnWfXtgf2c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:X5DP17 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-21250593 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250697|imex:IM-24135-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:w0LZNnJb8AS0knAnnHp44p5wWxA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12800 uniprotkb:X5DP17 intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915 intact:EBI-21250593 psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250689|imex:IM-24135-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:JdRDh3T4vDx6GmCTAB0rK8pe/xw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BQY4 uniprotkb:X5DP17 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-21250593 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250681|imex:IM-24135-919 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:cncpSnmZP8pFutvF1bl+PCfOBu0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:X5DP17 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-21250593 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250673|imex:IM-24135-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:Vh1xgp6syGpffPhIAEg9oM1EuZU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43586 uniprotkb:X5DP17 intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746 intact:EBI-21250593 psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250665|imex:IM-24135-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:W6taB0/ITLq2DTipr0C5ZISjZg8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H668 uniprotkb:X5DP17 intact:EBI-746930|uniprotkb:Q5TCZ0|uniprotkb:D3DR99|ensembl:ENSP00000224950|ensembl:ENSP00000358779 intact:EBI-21250593 psi-mi:stn1_human(display_long)|uniprotkb:STN1(gene name)|psi-mi:STN1(display_short)|uniprotkb:OBFC1(gene name synonym)|uniprotkb:Oligonucleotide/oligosaccharide-binding fold-containing protein 1(gene name synonym)|uniprotkb:Suppressor of cdc thirteen homolog(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250657|imex:IM-24135-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718039.1|refseq:NP_079204.2|ensembl:ENSG00000107960(gene)|ensembl:ENST00000224950(transcript)|ensembl:ENST00000369764(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016233"(telomere capping)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:1990879"(CST complex)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014647(Uncharacterised protein with OB-fold)|interpro:IPR015253(Region of unknown function DUF1879)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|interpro:IPR042082|rcsb pdb:4JOI|rcsb pdb:4JQF|rcsb pdb:6W6W|reactome:R-HSA-174411|reactome:R-HSA-174430|refseq:XP_016872158.1|refseq:XP_016872159.1|dip:DIP-59914N|entrezgene/locuslink:79991(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:bcmazDHRYRmgdk1waIzSspUjupY9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:/rZ7EXFq9l4T3+a/hzANHO86a5s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5DP17 intact:EBI-16439278 intact:EBI-21250593 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250649|imex:IM-24135-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:e6nWLPn7iCotWNDzjs1QnUu1WO4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50221 uniprotkb:X5DP17 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 intact:EBI-21250593 psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250641|imex:IM-24135-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:m9TJTNo7u1gVAVhK3bIBdrmEx5g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:X5DP17 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-21250593 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250633|imex:IM-24135-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:Zj2jaJHLkROKQWs834Kn9L5FM8k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VWP2 uniprotkb:X5DP17 intact:EBI-741787|uniprotkb:A3KMG2|uniprotkb:Q8NE25|uniprotkb:Q9NXK0|ensembl:ENSP00000358458 intact:EBI-21250593 psi-mi:tet5c_human(display_long)|uniprotkb:TENT5C(gene name)|psi-mi:TENT5C(display_short)|uniprotkb:FAM46C(gene name synonym)|uniprotkb:"Non-canonical poly(A) polymerase FAM46C"(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250625|imex:IM-24135-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060179.2|ensembl:ENSG00000183508(gene)|ensembl:ENST00000369448(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0048255"(mRNA stabilization)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR012937(Protein of unknown function DUF1693)|rcsb pdb:6W36|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|entrezgene/locuslink:54855(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Vx+IPZCDUOhOxZF7s1pu2XTLTYs9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:LaLaEtsP975kwesfCPw2enhQ5iU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13554-3 uniprotkb:X5DP17 intact:EBI-11523526|ensembl:ENSP00000351542 intact:EBI-21250593 psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250617|imex:IM-24135-1101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)|entrezgene/locuslink:816(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V." - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:xFZ6I28nhn1f51yHQT40APiEiTs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:X5DP17 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-21250593 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250609|imex:IM-24135-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:oLWuzWbz/T7juZTQddGm01CfMLY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:X5DP17 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-21250593 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250599|imex:IM-24135-1099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:wvSOkvRGH5fo7g7g08mYCTo10ng false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NF64 uniprotkb:X5D7R7 intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723 intact:EBI-21250265 psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250585|imex:IM-24135-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:gkO57EyOLACt/8WYxFQbasiqRro9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:1D9eRRC6+opvOFihQVLEQRcu7fQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A0C4DGF1 uniprotkb:X5D7R7 intact:EBI-10188476|ensembl:ENSP00000433657 intact:EBI-21250265 psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250577|imex:IM-24135-917 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:BJnl8a9xNYpDktdD4ZaX901Y4RI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:X5D7R7 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-21250265 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250569|imex:IM-24135-915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:l/pCTedLYUBHMst9WY+cw5Sm/u8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:X5D7R7 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-21250265 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250561|imex:IM-24135-717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:pN2M2PUgXdZY6f0x14eYXA71AyA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IWZ5 uniprotkb:X5D7R7 intact:EBI-5235829|intact:EBI-10172216|uniprotkb:A1L4B6|uniprotkb:A1L4B4|uniprotkb:Q8N832|uniprotkb:Q8NDL3|ensembl:ENSP00000286349 intact:EBI-21250265 psi-mi:tri42_human(display_long)|uniprotkb:TRIM42(gene name)|psi-mi:TRIM42(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250553|imex:IM-24135-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689829.3|ensembl:ENSG00000155890(gene)|ensembl:ENST00000286349(transcript)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR036116|interpro:IPR042765|entrezgene/locuslink:287015(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:cLHTKcNRr2xZE+yUrqw2xLaPeXY9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:GgZ8UmQzZ01CIicQv2uGf3pX4LM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:Q99608 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250960|imex:IM-24135-1113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:OjzpHVpD1lUMUU3I4K6w/Ng45C0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z5R6-2 uniprotkb:Q99608 intact:EBI-12059807|ensembl:ENSP00000349237 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:q7z5r6-2(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:PREL1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250952|imex:IM-24135-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000077420(gene)|ensembl:ENST00000356785(transcript)|intact:EBI-2818084(isoform-parent)|uniprotkb:Q7Z5R6-2(isoform-parent)|entrezgene/locuslink:54518(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yY1eNRBlY6dtad7mPNj7QYlnAqY9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:Xx9EoFxcy59XIRKjehaOYadlKAY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11533440 uniprotkb:I3L3G9 - intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:wac(display_short)|psi-mi:EBI-11533440(display_long) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250944|imex:IM-24135-1285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:51322(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - no-uniprot-update: - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1lJ64iBkqUGKNB4Lz3jsp7Xu2nE9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:eTL6nf7TZ3L46A3XdkAzQXJgnGY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6Y0 uniprotkb:I3L3G9 intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250936|imex:IM-24135-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:6n4c+5aQGlDEZTqjAO8WFYsbXbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UMX0 uniprotkb:I3L3G9 intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250928|imex:IM-24135-923 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:cYkYhhDSksOC3Uxqfd2Da77oz/s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99614 uniprotkb:I3L3G9 intact:EBI-742074|uniprotkb:Q9BVT3|uniprotkb:B2RCT2|uniprotkb:D3DQJ8|ensembl:ENSP00000231238|ensembl:ENSP00000429225|ensembl:ENSP00000507891 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:ttc1_human(display_long)|uniprotkb:TTC1(gene name)|psi-mi:TTC1(display_short)|uniprotkb:TPR1(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250920|imex:IM-24135-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269429.1|refseq:NP_003305.1|ensembl:ENST00000231238(transcript)|ensembl:ENST00000522793(transcript)|ensembl:ENST00000682719(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensembl:ENSG00000113312(gene)|entrezgene/locuslink:7265(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:jpDASWCrto0zMhBm3Cj9aDQURm09606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:5t5VehK+QM0QsegG6I1Ocz7qJ1g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:I3L3G9 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250912|imex:IM-24135-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:pxL43WDOCBfSvq8EihUZIJZTopg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:I3L3G9 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250904|imex:IM-24135-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:bobLYxxaXO9F1UrAFhN64zfsjNc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:I3L3G9 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250896|imex:IM-24135-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:j1TMoJCM+52f12KMYZNixO41uxk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZM8 uniprotkb:I3L3G9 intact:EBI-928842|uniprotkb:Q86T80|uniprotkb:Q8TAR7|uniprotkb:Q9UH50|uniprotkb:B3KP93|intact:EBI-2557484|intact:EBI-11041407|uniprotkb:D3DTS0|uniprotkb:J3QT32|ensembl:ENSP00000333982 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:ndel1_human(display_long)|uniprotkb:NDEL1(gene name)|psi-mi:NDEL1(display_short)|uniprotkb:Mitosin-associated protein 1(gene name synonym)|uniprotkb:EOPA(gene name synonym)|uniprotkb:MITAP1(gene name synonym)|uniprotkb:NUDEL(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250888|imex:IM-24135-1283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110435.1|refseq:NP_001020750.1|refseq:XP_016880674.1|refseq:XP_016880676.1|dip:DIP-29554N|ensembl:ENSG00000166579(gene)|ensembl:ENST00000334527(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032418"(lysosome localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043203"(axon hillock)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060053"(neurofilament cytoskeleton)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033493|interpro:IPR033494|mint:Q9GZM8|rcsb pdb:2V66|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:81565(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:AtOowum6Uvuo3WRFXzogoOiDSXk9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:114igSxiI5TbcqISlOwyQoMhgyc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14777 uniprotkb:I3L3G9 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250880|imex:IM-24135-725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N|entrezgene/locuslink:10403(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:nUGb/9Z3kdiOzzQqQ/oFW0MDgUs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NPJ6 uniprotkb:I3L3G9 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250872|imex:IM-24135-1281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:oZc/EIQvlwiB5/gbc9eH334DFIc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43364 uniprotkb:I3L3G9 intact:EBI-21249133|ensembl:ENSP00000222718|uniprotkb:A1L4K3|uniprotkb:B2RMW3 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:hxa2_human(display_long)|uniprotkb:Homeobox protein Hox-1K(gene name synonym)|uniprotkb:HOXA2(gene name)|psi-mi:HOXA2(display_short)|uniprotkb:HOX1K(gene name synonym) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250864|imex:IM-24135-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105996(gene)|ensembl:ENST00000222718(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-5617472|reactome:R-HSA-9010553|refseq:NP_006726.1|entrezgene/locuslink:3199(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WRTR8leN+sm4/brewa6Dtl/qdn89606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:GhE/SYuPiuMtjxj26Ha4Ckekc9Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:I3L3G9 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250856|imex:IM-24135-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:NHTQYUcQRFR95XAGEgiTZ5iFigs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TD17 uniprotkb:X5DRF9 intact:EBI-8643207|ensembl:ENSP00000420418|intact:MINT-8163335|uniprotkb:Q8TD18|uniprotkb:A8K384|uniprotkb:B4E377|uniprotkb:Q9P2K7|uniprotkb:Q9UDV8 intact:EBI-21250811 psi-mi:zn398_human(display_long)|uniprotkb:ZNF398(gene name)|psi-mi:ZNF398(display_short)|uniprotkb:KIAA1339(gene name synonym)|uniprotkb:ZER6(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein p52/p71(gene name synonym) psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250841|imex:IM-24135-723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000197024(gene)|ensembl:ENST00000475153(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:XP_011514743.1|refseq:NP_065832.1|refseq:NP_733787.1|entrezgene/locuslink:57541(identity) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vmzhbFftKf8nNZm8D3fQFGfjHuI9606 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rigid:y3N5fiGTmc6w4/S0y7HeY2c7Eek false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:X5DRF9 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-21250811 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250833|imex:IM-24135-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rigid:bg0MLTQXp+pxGjfsOEF5tr4UOnQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZM8 uniprotkb:X5DRF9 intact:EBI-928842|uniprotkb:Q86T80|uniprotkb:Q8TAR7|uniprotkb:Q9UH50|uniprotkb:B3KP93|intact:EBI-2557484|intact:EBI-11041407|uniprotkb:D3DTS0|uniprotkb:J3QT32|ensembl:ENSP00000333982 intact:EBI-21250811 psi-mi:ndel1_human(display_long)|uniprotkb:NDEL1(gene name)|psi-mi:NDEL1(display_short)|uniprotkb:Mitosin-associated protein 1(gene name synonym)|uniprotkb:EOPA(gene name synonym)|uniprotkb:MITAP1(gene name synonym)|uniprotkb:NUDEL(gene name synonym) psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250825|imex:IM-24135-721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110435.1|refseq:NP_001020750.1|refseq:XP_016880674.1|refseq:XP_016880676.1|dip:DIP-29554N|ensembl:ENSG00000166579(gene)|ensembl:ENST00000334527(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032418"(lysosome localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043203"(axon hillock)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060053"(neurofilament cytoskeleton)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033493|interpro:IPR033494|mint:Q9GZM8|rcsb pdb:2V66|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:81565(identity) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:AtOowum6Uvuo3WRFXzogoOiDSXk9606 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rigid:OVHevhSnLKYD+aoTa/lenwhseyY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DRF9 uniprotkb:X5DRF9 intact:EBI-21250811 intact:EBI-21250811 psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250817|imex:IM-24135-1279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rigid:WmncmAOu5z0VKqdaj/YDxZLmjUw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6Y0 uniprotkb:X5DP35 intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597 intact:EBI-21249101 psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250803|imex:IM-24135-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:NT+qIsTG7qffq12ijRq+Og0czMI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14373 uniprotkb:X5DP35 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-21249101 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250795|imex:IM-24135-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:o1bc6etTk6l2avC+faqO4dJzGEk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:X5DP35 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-21249101 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250787|imex:IM-24135-719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:VHdUTjutmkQnrIdlWJwNQGtobqA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZM8 uniprotkb:X5DP35 intact:EBI-928842|uniprotkb:Q86T80|uniprotkb:Q8TAR7|uniprotkb:Q9UH50|uniprotkb:B3KP93|intact:EBI-2557484|intact:EBI-11041407|uniprotkb:D3DTS0|uniprotkb:J3QT32|ensembl:ENSP00000333982 intact:EBI-21249101 psi-mi:ndel1_human(display_long)|uniprotkb:NDEL1(gene name)|psi-mi:NDEL1(display_short)|uniprotkb:Mitosin-associated protein 1(gene name synonym)|uniprotkb:EOPA(gene name synonym)|uniprotkb:MITAP1(gene name synonym)|uniprotkb:NUDEL(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250779|imex:IM-24135-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110435.1|refseq:NP_001020750.1|refseq:XP_016880674.1|refseq:XP_016880676.1|dip:DIP-29554N|ensembl:ENSG00000166579(gene)|ensembl:ENST00000334527(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032418"(lysosome localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043203"(axon hillock)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060053"(neurofilament cytoskeleton)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033493|interpro:IPR033494|mint:Q9GZM8|rcsb pdb:2V66|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:81565(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:AtOowum6Uvuo3WRFXzogoOiDSXk9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:JL5WeCVV9zchAhWiL+iE44C/HaU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13064 uniprotkb:X5DP35 intact:EBI-2340269|ensembl:ENSP00000313881 intact:EBI-21249101 psi-mi:mkrn3_human(display_long)|uniprotkb:MKRN3(gene name)|psi-mi:MKRN3(display_short)|uniprotkb:D15S9(gene name synonym)|uniprotkb:RNF63(gene name synonym)|uniprotkb:ZNF127(gene name synonym)|uniprotkb:Zinc finger protein 127(gene name synonym)|uniprotkb:RING finger protein 63(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-3(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250771|imex:IM-24135-1277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005655.1|ensembl:ENSG00000179455(gene)|ensembl:ENST00000314520(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026294|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|mint:Q13064|entrezgene/locuslink:7681(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:3sZzqtO8FoR/vVI64iFKb0iuuSc9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:G4jxOb042uhhM8DlberY34fUN9s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:X5DP35 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-21249101 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250763|imex:IM-24135-1111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:KgwCroyka2L7LoyPWQbbmweOLEg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:X5DP35 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-21249101 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250753|imex:IM-24135-1109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:vhjJjZlpvDimToZez0kHDEFDyNc false sufficient binding region:383-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IZU0 uniprotkb:X5DP35 intact:EBI-10175124|uniprotkb:Q8N7Z8|uniprotkb:Q0IJ68|ensembl:ENSP00000318716|ensembl:ENSP00000412606|ensembl:ENSP00000431456|ensembl:ENSP00000498495 intact:EBI-21249101 psi-mi:fam9b_human(display_long)|uniprotkb:FAM9B(gene name)|psi-mi:FAM9B(display_short) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250745|imex:IM-24135-1107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995321.1|refseq:XP_011543766.1|ensembl:ENSG00000177138(gene)|ensembl:ENST00000327220(transcript)|ensembl:ENST00000428477(transcript)|ensembl:ENST00000472522(transcript)|ensembl:ENST00000651278(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|entrezgene/locuslink:171483(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tEJbrpO7KWcw7izp1VJ+5q6Xces9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:Rp9gOfNO5bBFLrf90Z+WW2fapY8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D8V5 uniprotkb:X5DP35 intact:EBI-21247544 intact:EBI-21249101 psi-mi:x5d8v5_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250737|imex:IM-24135-1105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:zcWGe0gHIWD0FamIyAXG3hRd8QQ9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:LCE3RKRh2sK6IYCkRKEu3UOK1KE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A0C4DGF1 uniprotkb:X5DP17 intact:EBI-10188476|ensembl:ENSP00000433657 intact:EBI-21250593 psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short) psi-mi:x5dp17_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250713|imex:IM-24135-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606 rogid:ZzNZ4ZQb1SsZ+QclDgGexS8n+VE9606 rigid:b/YpEIJhlkuf0V1od+HJjaIe5fQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11957832 uniprotkb:Q99608 - intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:ccdc136(display_short)|psi-mi:EBI-11957832(display_long) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250968|imex:IM-24135-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:64753(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FWTUx0ZMr4g1buyVnmwu2LBoxaU9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:w2JCiGmZvCkBT/6j/ahHiPEfc7A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01850 uniprotkb:Q99608 intact:EBI-1181367|uniprotkb:Q13977|uniprotkb:A8K8A8|ensembl:ENSP00000268383 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:cdr2_human(display_long)|uniprotkb:Paraneoplastic cerebellar degeneration-associated antigen(gene name synonym)|uniprotkb:Major Yo paraneoplastic antigen(gene name synonym)|uniprotkb:CDR2(gene name)|psi-mi:CDR2(display_short)|uniprotkb:PCD17(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250976|imex:IM-24135-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001793.1|ensembl:ENSG00000140743(gene)|ensembl:ENST00000268383(transcript)|interpro:IPR026079|mint:Q01850|refseq:XP_005276559.1|entrezgene/locuslink:1039(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:TYCAl4weno3VU167nI6ARIiWQZY9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:qDSIBcI61K67swX1gkP84c4uwPo false sufficient binding region:12-454 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5DR67 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251295 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5dr67_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251308|imex:IM-24135-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:c2SYxaC0SWm3dgukY1X9r8U2BwM9606 rigid:sK+vhd98keQ4Ay9jzx2+93poTAI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IXF0 uniprotkb:A0A087WVE9 intact:EBI-11322367|uniprotkb:Q86US7|uniprotkb:Q86US6|uniprotkb:Q8IXF2|uniprotkb:Q9H323|uniprotkb:Q9BY81|uniprotkb:Q9Y4L8|ensembl:ENSP00000348460 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:npas3_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP6(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:Member of PAS protein 6(gene name synonym)|uniprotkb:PAS domain-containing protein 6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251287|imex:IM-24135-729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158221.1|refseq:NP_001159365.1|refseq:NP_071406.1|refseq:NP_775182.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|ensembl:ENSG00000151322(gene)|ensembl:ENST00000356141(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:64067(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fZP+yFdAxC/o3jdOZaOq1+zcTxw9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:q9gyaLYQt/LoSuUf0c3kLD1va6g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q02833 uniprotkb:Q99743 intact:EBI-929013|ensembl:ENSP00000380713|ensembl:ENSP00000479652|uniprotkb:Q3KP42|intact:EBI-11052282|uniprotkb:G5E9N9|uniprotkb:Q3KP41 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:rasf7_human(display_long)|uniprotkb:RASSF7(gene name)|psi-mi:RASSF7(display_short)|uniprotkb:C11orf13(gene name synonym)|uniprotkb:HRC1(gene name synonym)|uniprotkb:HRAS1-related cluster protein 1(gene name synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251279|imex:IM-24135-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099849(gene)|ensembl:ENSG00000273859(gene)|ensembl:ENST00000397583(transcript)|ensembl:ENST00000622905(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0034451"(centriolar satellite)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR000159(Ras-association)|interpro:IPR029071|interpro:IPR033593|interpro:IPR033631|refseq:NP_001137465.1|refseq:NP_001137466.1|refseq:NP_003466.1|refseq:XP_016873850.1|refseq:XP_016873851.1|entrezgene/locuslink:8045(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p1j9prChoZIecLZDG02TGJ0Z76I9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:EZbXzRW3wMUs/xh1o79FimDgmhg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14964 uniprotkb:Q99743 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251271|imex:IM-24135-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:9KCX9OBdPYLdbJsOkJntHN3Gcwk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43281-2 uniprotkb:Q99743 intact:EBI-11525448|ensembl:ENSP00000340607 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:o43281-2(display_long)|uniprotkb:CASS3(gene name synonym)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251263|imex:IM-24135-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-718488(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000351354(transcript)|uniprotkb:O43281-2(isoform-parent)|entrezgene/locuslink:10278(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JdV6uL2+FglKvl/B+OVXk/eIIKQ9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:c37Ud1fFU3fQhbx3bYsjXhSIpXc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43186 uniprotkb:Q99743 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251255|imex:IM-24135-1301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:VwWZb4CIiJNQauYftMAgU/U+gBY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WYA1-3 uniprotkb:Q99743 intact:EBI-12268276|ensembl:ENSP00000379238 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:q8wya1-3(display_long)|uniprotkb:ARNTL2(gene name)|psi-mi:ARNTL2(display_short)|uniprotkb:BHLHE6(gene name synonym)|uniprotkb:BMAL2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP9(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 2(gene name synonym)|uniprotkb:CLIF(gene name synonym)|uniprotkb:CYCLE-like factor(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 6(gene name synonym)|uniprotkb:MOP9(gene name synonym)|uniprotkb:Member of PAS protein 9(gene name synonym)|uniprotkb:PAS domain-containing protein 9(gene name synonym)|uniprotkb:PASD9(gene name synonym)|uniprotkb:BMAL2c(isoform synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251247|imex:IM-24135-925 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1793513(isoform-parent)|uniprotkb:Q8WYA1-3(isoform-parent)|ensembl:ENSG00000029153(gene)|ensembl:ENST00000395901(transcript)|entrezgene/locuslink:56938(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1LM/fdVsgt9kP/01RrddjciC49c9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:nUc7lT9CIRbXVhw2vuYGyTqwrgQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O00327-8 uniprotkb:Q99743 intact:EBI-11991546|ensembl:ENSP00000374357 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:o00327-8(display_long)|uniprotkb:ARNTL(gene name)|psi-mi:ARNTL(display_short)|uniprotkb:BHLHE5(gene name synonym)|uniprotkb:BMAL1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP3(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 5(gene name synonym)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Member of PAS protein 3(gene name synonym)|uniprotkb:PAS domain-containing protein 3(gene name synonym)|uniprotkb:PASD3(gene name synonym)|uniprotkb:bHLH-PAS protein JAP3(gene name synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251239|imex:IM-24135-1299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1794206(isoform-parent)|uniprotkb:O00327-8(isoform-parent)|ensembl:ENSG00000133794(gene)|ensembl:ENST00000389707(transcript)|entrezgene/locuslink:406(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qTVrFYWpZInEnhP8PZalZ02v5/Q9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:vm6jtoRQhKXUiK5C0wNd/TuF0fU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D307 intact:EBI-16439278 intact:EBI-21251217 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d307_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251231|imex:IM-24135-1297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|interpro:IPR029058|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR030024|entrezgene/locuslink:54413(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:hmE3Jokr8vsYp30SN3xrigbOAkU9606 rigid:HLDgO6GKTfrqM+AFFsNH+wHQ3do false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q9NZ94-3 intact:EBI-16439278 intact:EBI-21251202 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:q9nz943(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251209|imex:IM-24135-1295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) uniprotkb:Q9NZ94-3(isoform-parent)|entrezgene/locuslink:54413(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:kqgNr9xoF5wUvskSlac0cShDkjE9606 rigid:34jmx8kWNZ8oWPn/wOqgGxS583Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z4N8 uniprotkb:X5D2Y6 intact:EBI-10181968|uniprotkb:Q5JPA9|uniprotkb:Q5EBL3|uniprotkb:A0AV13|uniprotkb:B4DUD3|ensembl:ENSP00000332170 intact:EBI-21251186 psi-mi:p4ha3_human(display_long)|uniprotkb:P4HA3(gene name)|psi-mi:P4HA3(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3(gene name synonym)|uniprotkb:UNQ711/PRO1374(orf name) psi-mi:x5d2y6_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251194|imex:IM-24135-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001275677.1|refseq:NP_878907.1|ensembl:ENSG00000149380(gene)|ensembl:ENST00000331597(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|reactome:R-HSA-1650814|entrezgene/locuslink:283208(identity) go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048666"(neuron development)|interpro:IPR037445|interpro:IPR030086|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:d1yT0nxg2GYPUs3YnYr4MkodoAU9606 rogid:cfXjWa/w+qpnvsizFfD/Y69Nz7c9606 rigid:TDd8u5FtRuFGvUx4ZB73H6NCIdE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15156-2 uniprotkb:Q99608 intact:EBI-11522250|ensembl:ENSP00000406286 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251176|imex:IM-24135-1125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:41NEFYyprTXI+fOHVFh78TPKF289606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:X+Vgz5KT8eVX5br2AHBlnVIIAD4 false sufficient binding region:35-573 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y2K1 uniprotkb:Q99608 intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251168|imex:IM-24135-727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:N6YkkQaAFyOK6zOIJbfybCX9LSk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01081-2 uniprotkb:Q99608 intact:EBI-10176676|ensembl:ENSP00000369629 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:q01081-2(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:FP793(orf name)|uniprotkb:U2AF35b(isoform synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251158|imex:IM-24135-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160201(gene)|ensembl:ENST00000380276(transcript)|intact:EBI-632461(isoform-parent)|uniprotkb:Q01081-2(isoform-parent)|entrezgene/locuslink:7307(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - isoform-comment:Interacts with U2AF2 and stimulates U2AF splicing activity in vitro. Less efficient than isoform 1. Contains a N6-methyllysine at position 39. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:I2H9SB2+JgQhbwqaM8J+IE55xNg9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:kHuVCs68F6CromeE1K4Vsgju0qc false sufficient binding region:74-240 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04637 uniprotkb:Q99608 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251150|imex:IM-24135-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|entrezgene/locuslink:7157(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:Qomk7jHMHgxrYlQHAzuGj5e4ecg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBB9 uniprotkb:Q99608 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251142|imex:IM-24135-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|entrezgene/locuslink:24144(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:yIFjzQ8GrSM45Ez47aAQaR+Q7ME false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11742485 uniprotkb:Q99608 - intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:ssx2ip(display_short)|psi-mi:EBI-11742485(display_long) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251134|imex:IM-24135-1123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:117178(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7Bk1mdncQmcEYzJiNq9qdiPiJ6o9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:19gf1bYE/31HOs1T6ghIGmjjk58 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJW9 uniprotkb:Q99608 intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251126|imex:IM-24135-1121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:e8Y5pNDzRW8thoBokvAfadbTYIs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13136 uniprotkb:Q99608 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251118|imex:IM-24135-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500|entrezgene/locuslink:8500(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:FtOonRphoeiMOhQxfZyaZXkTpAk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UL45 uniprotkb:Q99608 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251110|imex:IM-24135-1293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1|entrezgene/locuslink:26258(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:aeeBZIkpoLGyp2JWhk2u1u8Ci9g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P07196 uniprotkb:Q99608 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251102|imex:IM-24135-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|entrezgene/locuslink:4747(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:00mYJSSSJXsSbQq7oMDFxqA45m8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WVE0 uniprotkb:Q99608 intact:EBI-16430415|ensembl:ENSP00000372202|ensembl:ENSP00000372206|uniprotkb:B5G4V1 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:efmt1_human(display_long)|uniprotkb:"N(6)-adenine-specific DNA methyltransferase 2"(gene name synonym)|uniprotkb:Protein-lysine N-methyltransferase N6AMT2(gene name synonym)|uniprotkb:EEF1AKMT1(gene name)|psi-mi:EEF1AKMT1(display_short)|uniprotkb:N6AMT2(gene name synonym)|uniprotkb:eEF1A-KMT(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251094|imex:IM-24135-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150456(gene)|ensembl:ENST00000382754(transcript)|ensembl:ENST00000382758(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018022"(peptidyl-lysine methylation)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR019369|interpro:IPR029063|interpro:IPR041370|reactome:R-HSA-8876725|refseq:NP_001305868.1|refseq:NP_777588.1|refseq:XP_016875921.1|entrezgene/locuslink:221143(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qKNqMbQPejzDNq5IswwsVDIUopY9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:F0O+chgUWIVbxDe6PC02n/pi9kM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H000 uniprotkb:Q99608 intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251086|imex:IM-24135-1119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000|entrezgene/locuslink:23609(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:85ar++ZCpOTzAKgve5fDoRqa1Wk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N344 uniprotkb:Q99608 intact:EBI-3504938|uniprotkb:Q9ULM7|intact:EBI-28983418|ensembl:ENSP00000264819 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:mier2_human(display_long)|uniprotkb:MIER2(gene name)|psi-mi:MIER2(display_short)|uniprotkb:KIAA1193(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251076|imex:IM-24135-1291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060020.1|ensembl:ENSP00000264819|ensembl:ENSG00000105556(gene)|ensembl:ENST00000264819(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR040138|entrezgene/locuslink:54531(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:hedPKzh11QzR2oqkwIv/Frvg5Yc9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:fCKkl3ZoCQ4RaembE8HUlj51i44 false sufficient binding region:37-545 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60711 uniprotkb:Q99608 intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251068|imex:IM-24135-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137467.1|refseq:NP_001294880.1|refseq:NP_004802.1|ensembl:ENSG00000110031(gene)|ensembl:ENST00000395074(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042995"(cell projection)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|entrezgene/locuslink:9404(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:XJXyJ2qrs0bmBfy66HkHPjeiTm8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IWV1-3 uniprotkb:Q99608 intact:EBI-12327415|ensembl:ENSP00000356186 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:q8iwv1-3(display_long)|uniprotkb:LAX1(gene name)|psi-mi:LAX1(display_short)|uniprotkb:LAX(gene name synonym)|uniprotkb:Linker for activation of X cells(gene name synonym)|uniprotkb:Membrane-associated adapter protein LAX(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251058|imex:IM-24135-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-10232942(isoform-parent)|ensembl:ENSG00000122188(gene)|ensembl:ENST00000367217(transcript)|uniprotkb:Q8IWV1-3(isoform-parent)|entrezgene/locuslink:54900(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fIN9VFNBayQpxaE9ntgA2qgoFJU9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:ae6BrDokqhDfIbVztivHxL5Ch+E false sufficient binding region:61-382 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q0D2I5-5 uniprotkb:Q99608 intact:EBI-21251044 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:q0d2i5-5(display_long)|uniprotkb:IFFO1(gene name)|psi-mi:IFFO1(display_short)|uniprotkb:IFFO(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251050|imex:IM-24135-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q0D2I5(isoform-parent)|entrezgene/locuslink:25900(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2020/12/14 rogid:ejVKGEK7P0bADSHkjcIcR+AJn+c9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:aZGKsK4SbYFxpes/4nX2YgpSpSU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:Q99608 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251034|imex:IM-24135-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:wLD2pxp0/LjNk6FgeYPyoJUiDaA false sufficient binding region:13-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VSY0 uniprotkb:Q99608 intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251026|imex:IM-24135-1289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WPAqDDTftv300tbwXkusTo6tmUo9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:ANFVMEZfGClwV8n+j9rl35Gu0r0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:Q99608 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251018|imex:IM-24135-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:IW1NpymYUn3Z/gEQCv3AGJi4Tbc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A1L4K1 uniprotkb:Q99608 intact:EBI-5661036|uniprotkb:B3KVG1|uniprotkb:B7ZM02|ensembl:ENSP00000335651 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:fsd2_human(display_long)|uniprotkb:SPRY domain-containing protein 1(gene name synonym)|uniprotkb:SPRYD1(gene name synonym)|uniprotkb:FSD2(gene name)|psi-mi:FSD2(display_short) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251010|imex:IM-24135-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007123.1|refseq:XP_005272482.1|refseq:NP_001268734.1|refseq:NP_001268735.1|ensembl:ENSG00000186628(gene)|ensembl:ENST00000334574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR043136|entrezgene/locuslink:123722(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XD3MwGtfyGillIn2aNaHaiAwEls9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:OL2noh7FeaYIgm51m5bwEQdbEu0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96AQ9 uniprotkb:Q99608 intact:EBI-741921|ensembl:ENSP00000364814|uniprotkb:Q5T5Q5|uniprotkb:Q8N3X3|uniprotkb:Q8N9P9 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:f131c_human(display_long)|uniprotkb:FAM131C(gene name)|psi-mi:FAM131C(display_short)|uniprotkb:C1orf117(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251002|imex:IM-24135-1117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185519(gene)|ensembl:ENST00000375662(transcript)|interpro:IPR026782|refseq:NP_872429.2|entrezgene/locuslink:348487(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:C85G7ipvJKdcueTSbK+r4W2cboM9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:KA2/PCuS0t5/cczGFYdARsO9A2U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y6B2 uniprotkb:Q99608 intact:EBI-1049975|uniprotkb:Q8N7I4|uniprotkb:Q9BZT9|uniprotkb:B2RD11|ensembl:ENSP00000431162 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:eid1_human(display_long)|uniprotkb:EID1(gene name)|psi-mi:EID1(display_short)|uniprotkb:C15orf3(gene name synonym)|uniprotkb:CRI1(gene name synonym)|uniprotkb:RBP21(gene name synonym)|uniprotkb:PNAS-22(orf name)|uniprotkb:PTD014(orf name)|uniprotkb:E1A-like inhibitor of differentiation 1(gene name synonym)|uniprotkb:CREBBP/EP300 inhibitory protein 1(gene name synonym)|uniprotkb:21 kDa pRb-associated protein(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250994|imex:IM-24135-1287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055150.1|ensembl:ENSG00000255302(gene)|ensembl:ENST00000530028(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR033255|interpro:IPR033258|mint:Q9Y6B2|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|entrezgene/locuslink:23741(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VPSCn0cgSMX+Pl+QwutWWqZseLQ9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:qjsLWk2+arLFqBvUHSp60sSZL1Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EV8 uniprotkb:Q99608 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-718177|uniprotkb:B2R6Z5|ensembl:ENSP00000497916 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:necd_human(display_long)|uniprotkb:NDN(gene name)|psi-mi:NDN(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21250986|imex:IM-24135-1115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity) refseq:NP_002478.1|ensembl:ENSG00000182636(gene)|ensembl:ENST00000649030(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002190(MAGE protein)|interpro:IPR030086|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-HSA-6785807|go:"GO:0008347"(glial cell migration)|entrezgene/locuslink:4692(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:8hFkLGNpSu6jmbrqmJuxNBZoWTs9606 rigid:uUNdPf9L7j5z4ScfgtNfis/f1nc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:O60260 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251451|imex:IM-24135-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:xOYs9y00A8MghVFchHCvMKpXo3I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15884-3 uniprotkb:O60260 intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251443|imex:IM-24135-1307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:AlME9fGNv4leIbIuBse4bown9Nc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:O60260 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251435|imex:IM-24135-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:q9XX5VO5034mvzUMXuQDwGvT9Iw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYM8 uniprotkb:O60260 intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251425|imex:IM-24135-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006453.1|refseq:NP_112506.2|ensembl:ENSG00000125826(gene)|ensembl:ENST00000356286(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR026261|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|dip:DIP-47737N|entrezgene/locuslink:10616(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:dkte2Xxd4M6FQLOHBVPzSU6XA5Q false sufficient binding region:11-510 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:O60260 intact:EBI-16439278 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251417|imex:IM-24135-1305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:GQCXNNKekp2WgkrzSYN6x34fYTQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50221 uniprotkb:O60260 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251409|imex:IM-24135-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:fq1i3EyI+7goHRie3ieSK7I9GJs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VWP2 uniprotkb:O60260 intact:EBI-741787|uniprotkb:A3KMG2|uniprotkb:Q8NE25|uniprotkb:Q9NXK0|ensembl:ENSP00000358458 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:tet5c_human(display_long)|uniprotkb:TENT5C(gene name)|psi-mi:TENT5C(display_short)|uniprotkb:FAM46C(gene name synonym)|uniprotkb:"Non-canonical poly(A) polymerase FAM46C"(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251401|imex:IM-24135-1127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060179.2|ensembl:ENSG00000183508(gene)|ensembl:ENST00000369448(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0048255"(mRNA stabilization)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR012937(Protein of unknown function DUF1693)|rcsb pdb:6W36|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|entrezgene/locuslink:54855(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Vx+IPZCDUOhOxZF7s1pu2XTLTYs9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:UBRxaY+TvaHI/Y9kJktW6fzLtLo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:O60260 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251393|imex:IM-24135-1303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:eQQevmdXqKTM5sdZ7uR808QcnFI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43186 uniprotkb:O60260 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251385|imex:IM-24135-731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:y4woVxHo8PGJSE2Kb0ZQVbehR7E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99719 uniprotkb:O60260 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251377|imex:IM-24135-929 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - crc64:47054765DEA10D33 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:2AO13wmqslLomd9OIiHrgFqes8I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR59-3 uniprotkb:Q8TB37 intact:EBI-11522433|ensembl:ENSP00000370186 intact:EBI-12852610|ensembl:ENSP00000281081|uniprotkb:B4DHZ1|uniprotkb:Q86TZ4|uniprotkb:Q9H9M2 psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym) psi-mi:nubpl_human(display_long)|uniprotkb:NUBPL(gene name)|psi-mi:NUBPL(display_short)|uniprotkb:C14orf127(gene name synonym)|uniprotkb:IND1 homolog(gene name synonym)|uniprotkb:Nucleotide-binding protein-like(gene name synonym)|uniprotkb:huInd1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251369|imex:IM-24135-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity) ensembl:ENSG00000151413(gene)|ensembl:ENST00000281081(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070584"(mitochondrion morphogenesis)|interpro:IPR000808(Mrp, conserved site)|interpro:IPR019591|interpro:IPR027417|interpro:IPR033756|interpro:IPR044304|reactome:R-HSA-6799198|refseq:NP_001188502.1|refseq:NP_079428.2|entrezgene/locuslink:80224(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:npId9tC7VoLN/jteoBiRbSYChPs9606 rogid:e9UiCfG76k75Df7cMDdOmi/LI7I9606 rigid:i6Va8k/tXRjjlOG1fgrkyZvRRgY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5D985 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251348 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5d985_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251361|imex:IM-24135-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:lLfxsDElLRVPopOfvUCTV9P2HMk9606 rigid:oaHv4KFiBcnlKR3cJUOSaFV9MQ4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:Q8IXF0-4 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251332 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf04(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251340|imex:IM-24135-927 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-4(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:YUGSAXzGTadX+uAOn9M1cRETk849606 rigid:4sTJxthwB3s8QHcxj0StfqtM1Ns false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:Q8IXF0-2 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251316 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf02(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251324|imex:IM-24135-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-2(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:EmOyLhrkc5xc32oixYjUy9hg1hU9606 rigid:Nn7em56imqLUurk4HZO5MXHQlxs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:O43741 intact:EBI-16439278 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251874|imex:IM-24135-951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:F8cDnp5OTO7iWvAg/yh5iQodvPw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50221 uniprotkb:O60260-5 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 intact:EBI-21251460 psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:o60260-5(display_long)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251466|imex:IM-24135-733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4222(identity) intact:EBI-716346(isoform-parent)|uniprotkb:O60260-5(isoform-parent)|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 rogid:br9pmy///67B150f8/qnWC84T7I9606 rigid:rCpRfqIfPTwcsX1fqkrOFu5464I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y5V3 uniprotkb:O43741 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251858|imex:IM-24135-949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:GPa6GlZu2YJPzILCcKUKlhSViIM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:O43741 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251850|imex:IM-24135-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:ziid2J2bToBkJPMtzTc/xjgxqpo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UIH9 uniprotkb:O43741 intact:EBI-2796400|ensembl:ENSP00000296233 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:klf15_human(display_long)|uniprotkb:KKLF(gene name synonym)|uniprotkb:Kidney-enriched krueppel-like factor(gene name synonym)|uniprotkb:KLF15(gene name)|psi-mi:KLF15(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251842|imex:IM-24135-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054798.1|refseq:XP_005247457.1|ensembl:ENSG00000163884(gene)|ensembl:ENST00000296233(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016607"(nuclear speck)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0032868"(response to insulin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9UIH9|rcsb pdb:2ENT|reactome:R-HSA-1368108|entrezgene/locuslink:28999(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vocV1ptKE68rlXylNPMj/4qjo689606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:W9hVr89j3CXPi4AcTAWgFP9FV3k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKT9 uniprotkb:O43741 intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251834|imex:IM-24135-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:zHaLgzipuzObROLxupd7ZUPAexk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13422-7 uniprotkb:O43741 intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251826|imex:IM-24135-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:RubF5gh8hQVjmRD2ZJ91VQh+f8A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q08379 uniprotkb:O43741 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251816|imex:IM-24135-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:nIQY2VB49/6NezKYIUwNvfXsLsA false sufficient binding region:383-1002 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7L5D6 uniprotkb:O43741 intact:EBI-711823|uniprotkb:A4D2Q1|uniprotkb:B3KNC7|uniprotkb:Q9UFC9|uniprotkb:Q9Y309|ensembl:ENSP00000265857 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:get4_human(display_long)|uniprotkb:CEE(gene name synonym)|uniprotkb:Conserved edge-expressed protein(gene name synonym)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:CGI-20(orf name)|uniprotkb:C7orf20(gene name synonym)|uniprotkb:TRC35(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 35 kDa subunit(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251808|imex:IM-24135-947 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000239857(gene)|ensembl:ENST00000265857(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0051087"(chaperone binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q7L5D6|rcsb pdb:6AU8|reactome:R-HSA-9609523|refseq:NP_057033.2|entrezgene/locuslink:51608(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:WbZJTGrC2/fB4iOFLJYn9MIWZFA9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:Oxr1h6EMOKE256hKvvUrrUndDQQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WXI9 uniprotkb:O43741 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251800|imex:IM-24135-745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|entrezgene/locuslink:57459(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:MLvJ7LKBVs7agJrLGKvDMWYmAY8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15976-2 uniprotkb:O43741 intact:EBI-9090198 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:p15976-2(display_long)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251792|imex:IM-24135-1313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3909284(isoform-parent)|uniprotkb:P15976-2(isoform-parent)|entrezgene/locuslink:2623(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:k5zPlmC/k7yYWDjUKg+PE9fGlcE9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:uER2qtoz8KpZMg2u6omSmllvKyY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14920 uniprotkb:O43741 intact:EBI-3908043|uniprotkb:Q16758|uniprotkb:B2R7I5|uniprotkb:Q8N6R2|ensembl:ENSP00000228476 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:oxda_human(display_long)|uniprotkb:DAO(gene name)|psi-mi:DAO(display_short)|uniprotkb:DAMOX(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251784|imex:IM-24135-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536306.1|refseq:XP_011536307.1|refseq:NP_001908.3|ensembl:ENSG00000110887(gene)|ensembl:ENST00000228476(transcript)|go:"GO:0003884"(D-amino-acid oxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006562"(proline catabolic process)|go:"GO:0019478"(D-amino acid catabolic process)|go:"GO:0036088"(D-serine catabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055130"(D-alanine catabolic process)|go:"GO:0070178"(D-serine metabolic process)|go:"GO:0071949"(FAD binding)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR006181(D-amino acid oxidase, conserved site)|interpro:IPR023209|rcsb pdb:2DU8|rcsb pdb:2E48|rcsb pdb:2E4A|rcsb pdb:2E82|rcsb pdb:2GNZ|rcsb pdb:3CUK|rcsb pdb:3G3E|rcsb pdb:3W4I|rcsb pdb:2E49|rcsb pdb:3W4J|rcsb pdb:3W4K|rcsb pdb:3ZNN|rcsb pdb:3ZNO|rcsb pdb:3ZNP|rcsb pdb:3ZNQ|rcsb pdb:4QFC|rcsb pdb:4QFD|rcsb pdb:5ZJ9|rcsb pdb:5ZJA|rcsb pdb:6KBP|reactome:R-HSA-389661|reactome:R-HSA-9033241|entrezgene/locuslink:1610(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNZI/65g5cH05GPqu0Yc0YUpVMg9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:xNAazftAAadvIXDoeXNGAvSU0LM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43186 uniprotkb:O43741 intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251776|imex:IM-24135-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:240GRRmKK1zB4YmOMCu4WRP0XWA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96BA8 uniprotkb:O43741 intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251768|imex:IM-24135-945 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE" - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:ci0Lu0hhk/nOZUATHpTHlLxlIFY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14627 uniprotkb:O43741 intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251760|imex:IM-24135-943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:qkoUe7LfypHfTGw1NcuMzZyeCj8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYA8 uniprotkb:O43741 intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251750|imex:IM-24135-1135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:aysBx/qGg92GKRQrcyTmE+dQr9w false sufficient binding region:11-594 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N5R6 uniprotkb:O43741 intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251742|imex:IM-24135-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2021/11/30 rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:M/CIzakKDSdwn9ClrlRckrwnv9Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:O43741 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251734|imex:IM-24135-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - crc64:609B121DA1A9DCB8 - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:3RuCffA5ZzC2xCWxl0RmHtJwiNY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5VWN6 uniprotkb:O43741 intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251724|imex:IM-24135-743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1|entrezgene/locuslink:54906(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:qg99G9JAhdp9cavV1eQdQD4ET18 false sufficient binding region:1690-2430 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H2G9 uniprotkb:O43741 intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251716|imex:IM-24135-941 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:rQ1P14h3jO4atxI2PT9AlkormoA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7L4P6 uniprotkb:O43741 intact:EBI-724373|ensembl:ENSP00000360899|uniprotkb:D3DQ27|uniprotkb:Q96A62|uniprotkb:Q9HAI3|intact:EBI-3044085 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:bend5_human(display_long)|uniprotkb:BEND5(gene name)|psi-mi:BEND5(display_short)|uniprotkb:C1orf165(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251708|imex:IM-24135-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078879.2|ensembl:ENSG00000162373(gene)|ensembl:ENST00000371833(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR018379|interpro:IPR040391|mint:Q7L4P6|refseq:NP_001289011.1|refseq:XP_011540444.1|refseq:XP_016857823.1|entrezgene/locuslink:79656(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R6OwgNU76FX6tqLRdHVmzEgK8EE9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:QwumGMl2GjZvwJF4TFbJndRJbZ4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N9N5-2 uniprotkb:O43741 intact:EBI-11524452|ensembl:ENSP00000347125 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251700|imex:IM-24135-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:u9BnuRP3Syph/M3HgudhJRGxH+E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14-3 uniprotkb:O43741 intact:EBI-10173507|ensembl:ENSP00000358035|ensembl:ENSP00000501295 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q6uy14-3(display_long)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251690|imex:IM-24135-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143382(gene)|ensembl:ENST00000369039(transcript)|ensembl:ENST00000674043(transcript)|intact:EBI-742002(isoform-parent)|uniprotkb:Q6UY14-3(isoform-parent)|entrezgene/locuslink:54507(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7EB8HdDfZI57O38GQO8ZSygWp2U9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:CXeiASocHJgjdI5kPhXJrXfZ8To false sufficient binding region:674-1097 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BSE2 uniprotkb:P26678 intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22 intact:EBI-692836|ensembl:ENSP00000350132 psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym) psi-mi:ppla_human(display_long)|uniprotkb:PLN(gene name)|psi-mi:PLN(display_short)|uniprotkb:PLB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251682|imex:IM-24135-939 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity) refseq:NP_002658.1|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032868"(response to insulin)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033574"(response to testosterone)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055119"(relaxation of cardiac muscle)|ensembl:ENSG00000198523(gene)|ensembl:ENST00000357525(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008015"(blood circulation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|dip:DIP-33582N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901894"(regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902081"(negative regulation of calcium ion import into sarcoplasmic reticulum)|interpro:IPR005984(Phospholamban)|rcsb pdb:1K9N|rcsb pdb:1KCH|rcsb pdb:1PLN|rcsb pdb:1PLP|rcsb pdb:1PSL|rcsb pdb:1ZLL|rcsb pdb:2HYN|rcsb pdb:6Y40|reactome:R-HSA-5578775|reactome:R-HSA-936837|entrezgene/locuslink:5350(identity) - comment:mint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606 rogid:Ez0SC8EfE4K9O9JI5wNGAHJUXOw9606 rigid:HejZpMqlpxORd+/kZNIhDKCxT74 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T700 uniprotkb:P26678 intact:EBI-10173166|uniprotkb:A0PJY0|uniprotkb:Q5T6Z9|uniprotkb:B7ZME3|ensembl:ENSP00000360411 intact:EBI-692836|ensembl:ENSP00000350132 psi-mi:lrad1_human(display_long)|uniprotkb:LDLRAD1(gene name)|psi-mi:LDLRAD1(display_short) psi-mi:ppla_human(display_long)|uniprotkb:PLN(gene name)|psi-mi:PLN(display_short)|uniprotkb:PLB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251674|imex:IM-24135-1311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010978.2|refseq:NP_001263321.1|refseq:NP_001263322.1|refseq:NP_001263323.1|ensembl:ENSG00000203985(gene)|ensembl:ENST00000371360(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR036055|interpro:IPR040093|entrezgene/locuslink:388633(identity) refseq:NP_002658.1|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032868"(response to insulin)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033574"(response to testosterone)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055119"(relaxation of cardiac muscle)|ensembl:ENSG00000198523(gene)|ensembl:ENST00000357525(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008015"(blood circulation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|dip:DIP-33582N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901894"(regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902081"(negative regulation of calcium ion import into sarcoplasmic reticulum)|interpro:IPR005984(Phospholamban)|rcsb pdb:1K9N|rcsb pdb:1KCH|rcsb pdb:1PLN|rcsb pdb:1PLP|rcsb pdb:1PSL|rcsb pdb:1ZLL|rcsb pdb:2HYN|rcsb pdb:6Y40|reactome:R-HSA-5578775|reactome:R-HSA-936837|entrezgene/locuslink:5350(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:rkl4hSqRJnoxozOwaZtQX76eSYM9606 rogid:Ez0SC8EfE4K9O9JI5wNGAHJUXOw9606 rigid:X8GW779mRyZthhkmDW67AcA5Y8Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92838 uniprotkb:P26678 intact:EBI-529425|uniprotkb:A0AUZ2|uniprotkb:A2A337|uniprotkb:O75910|uniprotkb:Q5JS00|uniprotkb:Q5JUM7|uniprotkb:Q9UP77|uniprotkb:Q9Y6L0|uniprotkb:Q9Y6L1|uniprotkb:Q9Y6L2|uniprotkb:Q9Y6L3|uniprotkb:Q9Y6L4|uniprotkb:B7ZLU2|uniprotkb:B7ZLU4|ensembl:ENSP00000363680 intact:EBI-692836|ensembl:ENSP00000350132 psi-mi:eda_human(display_long)|uniprotkb:Ectodermal dysplasia protein(gene name synonym)|uniprotkb:EDA(gene name)|psi-mi:EDA(display_short)|uniprotkb:ED1(gene name synonym)|uniprotkb:EDA2(gene name synonym) psi-mi:ppla_human(display_long)|uniprotkb:PLN(gene name)|psi-mi:PLN(display_short)|uniprotkb:PLB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251666|imex:IM-24135-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005609.1|refseq:NP_001005610.2|refseq:NP_001005612.2|refseq:NP_001005613.1|refseq:NP_001390.1|ensembl:ENSG00000158813(gene)|ensembl:ENST00000374552(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010467"(gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0038177"(death receptor agonist activity)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043473"(pigmentation)|go:"GO:0045177"(apical part of cell)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048513"(animal organ development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061153"(trachea gland development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1RJ7|rcsb pdb:1RJ8|reactome:R-HSA-5669034|entrezgene/locuslink:1896(identity) refseq:NP_002658.1|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032868"(response to insulin)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033574"(response to testosterone)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055119"(relaxation of cardiac muscle)|ensembl:ENSG00000198523(gene)|ensembl:ENST00000357525(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008015"(blood circulation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|dip:DIP-33582N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901894"(regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902081"(negative regulation of calcium ion import into sarcoplasmic reticulum)|interpro:IPR005984(Phospholamban)|rcsb pdb:1K9N|rcsb pdb:1KCH|rcsb pdb:1PLN|rcsb pdb:1PLP|rcsb pdb:1PSL|rcsb pdb:1ZLL|rcsb pdb:2HYN|rcsb pdb:6Y40|reactome:R-HSA-5578775|reactome:R-HSA-936837|entrezgene/locuslink:5350(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:eonj4+AITQKuO8trfPnhiVYqwoo9606 rogid:Ez0SC8EfE4K9O9JI5wNGAHJUXOw9606 rigid:iMqXfmU6i/BPLG2KS7X0IQYUoyE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A0C4DGF1 uniprotkb:P78337 intact:EBI-10188476|ensembl:ENSP00000433657 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251658|imex:IM-24135-937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:rS3S0yc72gygx6UXZywnk5Dm9WY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:P78337 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251650|imex:IM-24135-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:M1RJJZKMyI4g6Y/4+NR2a7treBY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99932-2 uniprotkb:P78337 intact:EBI-11959123|ensembl:ENSP00000340982 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:q99932-2(display_long)|uniprotkb:SPAG8(gene name)|psi-mi:SPAG8(display_short)|uniprotkb:HSD-1(gene name synonym)|uniprotkb:Sperm membrane protein 1(gene name synonym)|uniprotkb:Sperm membrane protein BS-84(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251642|imex:IM-24135-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137098(gene)|ensembl:ENST00000340291(transcript)|intact:EBI-954419(isoform-parent)|uniprotkb:Q99932-2(isoform-parent)|entrezgene/locuslink:26206(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:hjK59L/npfXM4QX1s+4IiAaAHfo9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:Z6xf6wYIYmo3eSW+TcVHUY2/+rY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EP0 uniprotkb:P78337 intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251632|imex:IM-24135-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN|entrezgene/locuslink:55072(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:5QylozByg2G8/5LnkorkdY5fPec9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:9a7jp8YWbTzySQRdyOuEx/7HroU false sufficient binding region:484-1072 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8HWS3 uniprotkb:P78337 intact:EBI-746118|uniprotkb:Q5T6B3|ensembl:ENSP00000332208 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:rfx6_human(display_long)|uniprotkb:RFX6(gene name)|psi-mi:RFX6(display_short)|uniprotkb:RFXDC1(gene name synonym)|uniprotkb:Regulatory factor X 6(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 1(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251624|imex:IM-24135-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775831.2|ensembl:ENSG00000185002(gene)|ensembl:ENST00000332958(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003311"(pancreatic D cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0090104"(pancreatic epsilon cell differentiation)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|reactome:R-HSA-210745|entrezgene/locuslink:222546(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:R+QlHzmQeSg5ysiHPI4G8+NSYhE9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:OaA7LUokzlYfIvcuo4QNTFGRurA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:P78337 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251616|imex:IM-24135-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:jNqQdRpPWsq6E3A2qTD32exQerM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P86479 uniprotkb:P78337 intact:EBI-10172814|uniprotkb:Q8N7V5|ensembl:ENSP00000438757|ensembl:ENSP00000480729 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:pr20c_human(display_long)|uniprotkb:PRR20C(gene name)|psi-mi:PRR20C(display_short) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251608|imex:IM-24135-935 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016855016.1|refseq:NP_001123876.1|refseq:NP_001123877.1|refseq:NP_001123878.1|refseq:NP_001123879.1|refseq:NP_940843.1|ensembl:ENSG00000229665(gene)|ensembl:ENST00000544357(transcript)|ensembl:ENST00000614894(transcript)|interpro:IPR031439|entrezgene/locuslink:122183(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2wZckiY1jYSxwgm2NPfkiJDu4Bw9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:uVh5W7ulKLIpMo+WZpQdzpj72JE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15162 uniprotkb:P78337 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251600|imex:IM-24135-741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:AxcTUaBBUPBv91oqyb4lQhU+Aoo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-11956717 uniprotkb:P78337 - intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:mgat5b(display_short)|psi-mi:EBI-11956717(display_long) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251592|imex:IM-24135-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:146664(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:u1P8VoA3bBCR4LJMj7ZmpveS1sI9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:jUNVxBg+OlL8SRFzqkP6LLpgueY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y5V3 uniprotkb:P78337 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251584|imex:IM-24135-933 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|entrezgene/locuslink:9500(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:nMZ5Ry1y3OL5dNlRQRlPZ/LTHMA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BRK4 uniprotkb:P78337 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251576|imex:IM-24135-739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:GRTegA9DOZ1Z2hEPABaeeJh0L4g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94829 uniprotkb:P78337 intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251568|imex:IM-24135-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY|entrezgene/locuslink:9670(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:wA4412Rr9DXgL1BVJodj0QSgZOo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14964 uniprotkb:P78337 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251560|imex:IM-24135-931 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:cbnzsZnXAyilrU70uGRmQBaAQz8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14627 uniprotkb:P78337 intact:EBI-10181162|uniprotkb:Q5JS20|uniprotkb:A1A513|ensembl:ENSP00000362613 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:cdx4_human(display_long)|uniprotkb:CDX4(gene name)|psi-mi:CDX4(display_short)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251552|imex:IM-24135-737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005184.1|ensembl:ENSG00000131264(gene)|ensembl:ENST00000373514(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:1046(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VjY+YbGRK+B4KOkI47ekRlWKivE9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:RI4OJEzSFvKo1avXZKd+lCTE19U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:P78337 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251542|imex:IM-24135-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:sSKNXjuFUYqhXpfUFVKWoOQ/ELA false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NP73-4 uniprotkb:P78337 intact:EBI-10186621|ensembl:ENSP00000251943|ensembl:ENSP00000392990|ensembl:ENSP00000481509 intact:EBI-748265|uniprotkb:O14677|uniprotkb:O60425|uniprotkb:Q9BTI5|uniprotkb:A8K3M0|uniprotkb:D3DQB0|ensembl:ENSP00000265340|ensembl:ENSP00000427542 psi-mi:q9np73-4(display_long)|uniprotkb:Asparagine-linked glycosylation 13 homolog(gene name synonym)|uniprotkb:CXorf45(gene name synonym)|uniprotkb:GLT28D1(gene name synonym)|uniprotkb:Glycosyltransferase 28 domain-containing protein 1(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine transferase subunit ALG13 homolog(gene name synonym)|uniprotkb:MDS031(orf name)|uniprotkb:ALG13(gene name)|psi-mi:ALG13(display_short) psi-mi:pitx1_human(display_long)|uniprotkb:Hindlimb-expressed homeobox protein backfoot(gene name synonym)|uniprotkb:PITX1(gene name)|psi-mi:PITX1(display_short)|uniprotkb:BFT(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 1(gene name synonym)|uniprotkb:Homeobox protein PITX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251532|imex:IM-24135-1309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-947892(isoform-parent)|ensembl:ENSG00000101901(gene)|ensembl:ENST00000251943(transcript)|ensembl:ENST00000436609(transcript)|ensembl:ENST00000621367(transcript)|uniprotkb:Q9NP73-4(isoform-parent)|entrezgene/locuslink:79868(identity) refseq:NP_002644.4|ensembl:ENSG00000069011(gene)|ensembl:ENST00000265340(transcript)|ensembl:ENST00000506438(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|go:"GO:0000785"(chromatin)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|entrezgene/locuslink:5307(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kdF/foB7v2Vv5e1Qene8EAB2wig9606 rogid:8NVPs8muaXuEuLsRPe8GYJ6P7sw9606 rigid:GYhwsSaXPDqeeZi65fpLhYRK6FQ false sufficient binding region:496-954 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:J3QSH9 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-10178671|ensembl:ENSP00000464696 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:j3qsh9_human(display_long)|uniprotkb:PER1(gene name)|psi-mi:PER1(display_short)|uniprotkb:hCG_31279(orf name) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251524|imex:IM-24135-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) ensembl:ENSG00000179094(gene)|ensembl:ENST00000581395(transcript)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR035965|entrezgene/locuslink:5187(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:vlxfU3BF7ss3z6AjAdQVRA3zUHo9606 rigid:T2wN1hUW6Xv5Ejwhjp6DxylrpRs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2TAC2-2 uniprotkb:J3QSH9 intact:EBI-10961624|ensembl:ENSP00000376154 intact:EBI-10178671|ensembl:ENSP00000464696 psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short) psi-mi:j3qsh9_human(display_long)|uniprotkb:PER1(gene name)|psi-mi:PER1(display_short)|uniprotkb:hCG_31279(orf name) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251516|imex:IM-24135-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity) ensembl:ENSG00000179094(gene)|ensembl:ENST00000581395(transcript)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR035965|entrezgene/locuslink:5187(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:RWcF0hgb1geIY959JUKrLK13Jx09606 rogid:vlxfU3BF7ss3z6AjAdQVRA3zUHo9606 rigid:YWZwrsugWkhWu0SfuAheml1K6O8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:Q6IN51 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-10250187 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:q6in51_human(display_long)|uniprotkb:PER1(gene name)|psi-mi:PER1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251508|imex:IM-24135-1133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) entrezgene/locuslink:5187(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:sg3cKm1xJqlq83EecmnKMZe6Wlo9606 rigid:SuvWxE/HnMbrvnsf/V6AuqDavCQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95199 uniprotkb:Q07343 intact:EBI-742404|uniprotkb:B2RDW8|ensembl:ENSP00000345144 intact:EBI-1105102|uniprotkb:O15443|uniprotkb:Q5TEK4|uniprotkb:Q5TEK6|uniprotkb:Q13945|uniprotkb:Q5TEK5|uniprotkb:A5YW33|ensembl:ENSP00000332116|ensembl:ENSP00000342637 psi-mi:rcbt2_human(display_long)|uniprotkb:RCBTB2(gene name)|psi-mi:RCBTB2(display_short)|uniprotkb:CHC1L(gene name synonym)|uniprotkb:RLG(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 2(gene name synonym)|uniprotkb:Chromosome condensation 1-like(gene name synonym)|uniprotkb:RCC1-like G exchanging factor(gene name synonym) psi-mi:pde4b_human(display_long)|uniprotkb:PDE4B(gene name)|psi-mi:PDE4B(display_short)|uniprotkb:DPDE4(gene name synonym)|uniprotkb:PDE32(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251500|imex:IM-24135-1131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001259.1|refseq:NP_001273759.1|refseq:NP_001273760.1|refseq:NP_001273761.1|refseq:XP_005266299.1|refseq:XP_005266301.1|refseq:XP_006719822.1|ensembl:ENSG00000136161(gene)|ensembl:ENST00000344532(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:1102(identity) refseq:NP_001284369.1|refseq:NP_001284370.1|refseq:NP_001284371.1|refseq:NP_001032416.1|refseq:NP_001032417.1|refseq:NP_001032418.1|refseq:NP_002591.2|ensembl:ENSG00000184588(gene)|ensembl:ENST00000329654(transcript)|ensembl:ENST00000341517(transcript)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|interpro:IPR040844|interpro:IPR043371|rcsb pdb:1F0J|rcsb pdb:1JP1|rcsb pdb:1JP2|rcsb pdb:1RO6|rcsb pdb:1RO9|rcsb pdb:1ROR|rcsb pdb:1TB5|rcsb pdb:1XLX|rcsb pdb:1XLZ|go:"GO:1901898"(negative regulation of relaxation of cardiac muscle)|rcsb pdb:1XM4|rcsb pdb:1XM6|rcsb pdb:1XMU|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006198"(cAMP catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030018"(Z disc)|go:"GO:0030552"(cAMP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0035690"|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0060076"(excitatory synapse)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:1XN0|rcsb pdb:1XOS|rcsb pdb:1XOT|rcsb pdb:1Y2H|rcsb pdb:1Y2J|rcsb pdb:2CHM|rcsb pdb:2QYL|rcsb pdb:3D3P|rcsb pdb:3FRG|rcsb pdb:3G45|rcsb pdb:3GWT|rcsb pdb:3HC8|rcsb pdb:3HDZ|rcsb pdb:3HMV|rcsb pdb:3KKT|rcsb pdb:3LY2|rcsb pdb:3O0J|rcsb pdb:3O56|rcsb pdb:3O57|rcsb pdb:3W5E|rcsb pdb:3WD9|rcsb pdb:4KP6|rcsb pdb:4MYQ|rcsb pdb:4NW7|rcsb pdb:4WZI|rcsb pdb:4X0F|rcsb pdb:5K6J|rcsb pdb:5LAQ|rcsb pdb:5OHJ|rcsb pdb:1XMY|rcsb pdb:6BOJ|reactome:R-HSA-180024|entrezgene/locuslink:5142(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VJjauSy5q9k4V5QceqoSYZQ5ep49606 rogid:wWvw53/tMzV6wpe/mSekC0iW+lg9606 rigid:w1g/ZVMjfgXpoBSmsdOGdT+EZ74 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43364 uniprotkb:Q07343 intact:EBI-739552|uniprotkb:Q5ETU4|uniprotkb:Q6ZRZ5|ensembl:ENSP00000347358 intact:EBI-1105102|uniprotkb:O15443|uniprotkb:Q5TEK4|uniprotkb:Q5TEK6|uniprotkb:Q13945|uniprotkb:Q5TEK5|uniprotkb:A5YW33|ensembl:ENSP00000332116|ensembl:ENSP00000342637 psi-mi:magab_human(display_long)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)|uniprotkb:MAGE11(gene name synonym)|uniprotkb:MAGE-11 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.11(gene name synonym) psi-mi:pde4b_human(display_long)|uniprotkb:PDE4B(gene name)|psi-mi:PDE4B(display_short)|uniprotkb:DPDE4(gene name synonym)|uniprotkb:PDE32(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251490|imex:IM-24135-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011544.1|refseq:NP_005357.2|ensembl:ENSG00000185247(gene)|ensembl:ENST00000355220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43364|rcsb pdb:6WJH|refseq:XP_016885010.1|refseq:XP_016885011.1|entrezgene/locuslink:4110(identity) refseq:NP_001284369.1|refseq:NP_001284370.1|refseq:NP_001284371.1|refseq:NP_001032416.1|refseq:NP_001032417.1|refseq:NP_001032418.1|refseq:NP_002591.2|ensembl:ENSG00000184588(gene)|ensembl:ENST00000329654(transcript)|ensembl:ENST00000341517(transcript)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|interpro:IPR040844|interpro:IPR043371|rcsb pdb:1F0J|rcsb pdb:1JP1|rcsb pdb:1JP2|rcsb pdb:1RO6|rcsb pdb:1RO9|rcsb pdb:1ROR|rcsb pdb:1TB5|rcsb pdb:1XLX|rcsb pdb:1XLZ|go:"GO:1901898"(negative regulation of relaxation of cardiac muscle)|rcsb pdb:1XM4|rcsb pdb:1XM6|rcsb pdb:1XMU|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006198"(cAMP catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030018"(Z disc)|go:"GO:0030552"(cAMP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0035690"|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0060076"(excitatory synapse)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:1XN0|rcsb pdb:1XOS|rcsb pdb:1XOT|rcsb pdb:1Y2H|rcsb pdb:1Y2J|rcsb pdb:2CHM|rcsb pdb:2QYL|rcsb pdb:3D3P|rcsb pdb:3FRG|rcsb pdb:3G45|rcsb pdb:3GWT|rcsb pdb:3HC8|rcsb pdb:3HDZ|rcsb pdb:3HMV|rcsb pdb:3KKT|rcsb pdb:3LY2|rcsb pdb:3O0J|rcsb pdb:3O56|rcsb pdb:3O57|rcsb pdb:3W5E|rcsb pdb:3WD9|rcsb pdb:4KP6|rcsb pdb:4MYQ|rcsb pdb:4NW7|rcsb pdb:4WZI|rcsb pdb:4X0F|rcsb pdb:5K6J|rcsb pdb:5LAQ|rcsb pdb:5OHJ|rcsb pdb:1XMY|rcsb pdb:6BOJ|reactome:R-HSA-180024|entrezgene/locuslink:5142(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S0eOQssWhZCbAvWQCub2H+zQmzs9606 rogid:wWvw53/tMzV6wpe/mSekC0iW+lg9606 rigid:6TfrvcOggGxAyGDShuuPHje7AGc false sufficient binding region:111-429 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q9HC56 intact:EBI-16439278 intact:EBI-766147|uniprotkb:A2A6U1|uniprotkb:Q7Z3U0|uniprotkb:Q8N3K7|uniprotkb:Q5VT83|ensembl:ENSP00000367096 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:pcdh9_human(display_long)|uniprotkb:PCDH9(gene name)|psi-mi:PCDH9(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251482|imex:IM-24135-735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) refseq:NP_065136.1|refseq:NP_982354.1|refseq:NP_001305301.1|refseq:NP_001305302.1|refseq:XP_016876108.1|ensembl:ENSG00000184226(gene)|ensembl:ENST00000377865(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0030426"(growth cone)|go:"GO:0030900"(forebrain development)|go:"GO:0044291"(cell-cell contact zone)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR013585(Protocadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|mint:Q9HC56|rcsb pdb:2EE0|entrezgene/locuslink:5101(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:tjDnn/S8gv/IEABp7YPqdoKpvOw9606 rigid:buJtN5NOCHQj/moFbBIs1lTA0DQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:O60260-5 intact:EBI-16439278 intact:EBI-21251460 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:o60260-5(display_long)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251474|imex:IM-24135-1129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) intact:EBI-716346(isoform-parent)|uniprotkb:O60260-5(isoform-parent)|entrezgene/locuslink:5071(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:br9pmy///67B150f8/qnWC84T7I9606 rigid:2f4Pbq5JtYgBoYfvjHwBI2pWE0o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:O43741 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251866|imex:IM-24135-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:H/Jzg7INhHt2kJdtt3ykJmSXG4Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75928-2 uniprotkb:O43741 intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251890|imex:IM-24135-747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562." - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:HcZ3YTjPiRdYpVFrkLQLlNI4BDw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76041 uniprotkb:O43741 intact:EBI-2880203|ensembl:ENSP00000366326|uniprotkb:B0YJ45|uniprotkb:Q2TBD0|uniprotkb:Q9UIC4|uniprotkb:B9EIM9|uniprotkb:E9PRX7|uniprotkb:Q5VZT2|uniprotkb:Q70I54 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:nebl_human(display_long)|uniprotkb:NEBL(gene name)|psi-mi:NEBL(display_short)|uniprotkb:Actin-binding Z-disk protein(gene name synonym)|uniprotkb:LNEBL(gene name synonym)|uniprotkb:C10orf113(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251882|imex:IM-24135-1315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078114(gene)|ensembl:ENST00000377122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0031674"(I band)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028|mint:O76041|rcsb pdb:4F14|refseq:NP_006384.1|refseq:NP_001166955.1|refseq:NP_998734.1|entrezgene/locuslink:10529(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:6+3t3OOFerBzWUyX3qtfz4DhFdg9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:JhOi0re7vM4g0XNYFleRYGXTRpk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZV8 uniprotkb:O43741 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251898|imex:IM-24135-1317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:5pcW5e9EbAZPLpMkKxOlE4R2Fus false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13131 uniprotkb:O43741 intact:EBI-1181405|uniprotkb:O00286|uniprotkb:Q5D0E1|uniprotkb:Q9UNQ4|uniprotkb:Q86VS1|intact:EBI-1383523|uniprotkb:A8MTQ6|uniprotkb:B2R7E1|ensembl:ENSP00000380317 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:aapk1_human(display_long)|uniprotkb:PRKAA1(gene name)|psi-mi:PRKAA1(display_short)|uniprotkb:AMPK1(gene name synonym)|uniprotkb:Tau-protein kinase PRKAA1(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251906|imex:IM-24135-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006242.5|refseq:NP_996790.3|ensembl:ENSG00000132356(gene)|ensembl:ENST00000397128(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009411"(response to UV)|go:"GO:0009631"(cold acclimation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031000"(response to caffeine)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046318"(negative regulation of glucosylceramide biosynthetic process)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048156"(tau protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061744"(motor behavior)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120188"(regulation of bile acid secretion)|go:"GO:1901563"(response to camptothecin)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:1904486"(response to 17alpha-ethynylestradiol)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028797|interpro:IPR032270|interpro:IPR039137|mint:Q13131|rcsb pdb:4RED|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:5EZV|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1632852|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9619483|dip:DIP-39973N|entrezgene/locuslink:5562(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:isWWA5k0AqbXwXq5Bj+pk0joegU9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:WE2HbBYC8tNiRR3uqdO3NPaWn7o false sufficient binding region:10-559 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54646 uniprotkb:O43741 intact:EBI-1383852|uniprotkb:Q9H1E8|uniprotkb:Q9UD43|ensembl:ENSP00000360290 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:aapk2_human(display_long)|uniprotkb:PRKAA2(gene name)|psi-mi:PRKAA2(display_short)|uniprotkb:AMPK(gene name synonym)|uniprotkb:AMPK2(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251916|imex:IM-24135-1137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006243.2|dip:DIP-39796N|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048511"(rhythmic process)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0030424"(axon)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028783|interpro:IPR032270|interpro:IPR039148|mint:P54646|rcsb pdb:2H6D|rcsb pdb:3AQV|rcsb pdb:2LTU|rcsb pdb:2YZA|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6BX6|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|ensembl:ENSG00000162409(gene)|ensembl:ENST00000371244(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|entrezgene/locuslink:5563(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2t/qHlT6HwqoLLbMjjbhOaCZ1Ow9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:v2J+0hmhOGyOyFWAc4Hrf2P9rAg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54619 uniprotkb:O43741 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251924|imex:IM-24135-1319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N|entrezgene/locuslink:5571(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:Bn13oMnm7CrBUWta7snHPhA00ug false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P61289 uniprotkb:O43741 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251932|imex:IM-24135-749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:AAqGc18adbjFC3lOzI0Onmh4G6Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11217 uniprotkb:O43741 intact:EBI-357469|uniprotkb:A0AVK1|uniprotkb:A6NDY6|ensembl:ENSP00000164139 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:pygm_human(display_long)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251940|imex:IM-24135-1139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005600.1|refseq:NP_001158188.1|ensembl:ENSG00000068976(gene)|ensembl:ENST00000164139(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1Z8D|reactome:R-HSA-70221|entrezgene/locuslink:5837(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:6sb3nch9lDPt9m4R3UkUMNUmKys9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:a0savkZvvVpWi1cdFEYefaNZJcw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:O43741 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251948|imex:IM-24135-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:MmMY99AbfuVR8lRfv6g5Q9m9OD8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UFD9 uniprotkb:O43741 intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251972|imex:IM-24135-751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:7x6CtexzCXCZtniZMrztlTXCesY false sufficient binding region:838-1639 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TAI7 uniprotkb:O43741 intact:EBI-746555|uniprotkb:Q56VH8|ensembl:ENSP00000301068 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:rebl1_human(display_long)|uniprotkb:Ras homolog enriched in brain-like protein 1(gene name synonym)|uniprotkb:Rheb2(gene name synonym)|uniprotkb:Ras homolog enriched in brain like-1 c(gene name synonym)|uniprotkb:RHEBL1(gene name)|psi-mi:RHEBL1(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251964|imex:IM-24135-1321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653194.1|refseq:NP_001290055.1|ensembl:ENSG00000167550(gene)|ensembl:ENST00000301068(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:3OES|entrezgene/locuslink:121268(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:mHmXUvULxk42M1kPOjh4jsn4Q3w9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:UWvlsEk1rq66A8Tc53unlGVPE/s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:O43741 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251956|imex:IM-24135-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:T1YTZ9QwYIH/6cko3oiAV/z8/t8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43597 uniprotkb:O43741 intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251982|imex:IM-24135-953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:u1omauzisc6MdZlogMotUmtauSI9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:z+4SAzjWnCc4/U8C0N0r5vxKrPQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75558 uniprotkb:O43741 intact:EBI-714135|uniprotkb:O75378|uniprotkb:O95148|uniprotkb:Q5TCL6|ensembl:ENSP00000356540|uniprotkb:E1P598 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:stx11_human(display_long)|uniprotkb:STX11(gene name)|psi-mi:STX11(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251990|imex:IM-24135-1141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028672|interpro:IPR042781|mint:O75558|ensembl:ENSG00000135604(gene)|ensembl:ENST00000367568(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0061025"(membrane fusion)|refseq:NP_003755.2|refseq:XP_016866889.1|refseq:XP_011534516.1|refseq:XP_011534519.1|refseq:XP_011534520.1|entrezgene/locuslink:8676(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:LckEg7WERVC628sZGjvi3qlYJ549606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:ctwc/OvgWzMd6Ab5RSJtMvRrrUA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N4C7 uniprotkb:O43741 intact:EBI-8484990|intact:MINT-6940674|ensembl:ENSP00000320679 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:stx19_human(display_long)|uniprotkb:STX19(gene name)|psi-mi:STX19(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21251998|imex:IM-24135-1143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011511144.1|refseq:NP_001001850.1|ensembl:ENSG00000178750(gene)|ensembl:ENST00000315099(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015708(Syntaxin-3)|mint:Q8N4C7|entrezgene/locuslink:415117(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - comment:mint|comment:homomint - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FNBoXbeKnFcWR1+dwnaJVvWJ23c9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:kXdwCy0y7R4CLDE0qZ++K3Y6ahc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75478 uniprotkb:O43741 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252006|imex:IM-24135-753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|entrezgene/locuslink:6871(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:zwdhM+jjo8TXhW4BAnvz98KUe3A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15884-3 uniprotkb:O43741 intact:EBI-13636688|ensembl:ENSP00000346440|ensembl:ENSP00000486670 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:p15884-3(display_long)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:B+(isoform synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252014|imex:IM-24135-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-533224(isoform-parent)|ensembl:ENSG00000196628(gene)|ensembl:ENST00000354452(transcript)|ensembl:ENST00000629387(transcript)|uniprotkb:P15884-3(isoform-parent)|entrezgene/locuslink:6925(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ZNbTMfCK9F8zDtvfNHuHnQpJM7w9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:EZUD8TUb0nspR/DaNxkHPZRKEyk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:Q16623 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252256|imex:IM-24135-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:CgdKW8T+CCuldzBBg06m2QY2au4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H115 uniprotkb:Q16623 intact:EBI-3921185|ensembl:ENSP00000366225|uniprotkb:Q4G187|uniprotkb:Q5JXF9|uniprotkb:Q8N3C4|uniprotkb:B4DK44|uniprotkb:Q4G0M0 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:snab_human(display_long)|uniprotkb:NAPB(gene name)|psi-mi:NAPB(display_short)|uniprotkb:SNAPB(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein beta(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252248|imex:IM-24135-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125814(gene)|ensembl:ENST00000377026(transcript)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_071363.1|refseq:NP_001269947.1|refseq:NP_001269949.1|refseq:NP_001269955.1|entrezgene/locuslink:63908(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tKGtS2Dzj2CNItyIHAI2LOIiGyU9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:EbZojxbV1H3GnmsjFKpeZ+OKjhE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:P63162 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-712493|ensembl:ENSP00000463458|ensembl:ENSP00000494831|ensembl:ENSP00000495345|ensembl:ENSP00000306223|ensembl:ENSP00000375105|ensembl:ENSP00000382969|ensembl:ENSP00000382972|uniprotkb:P14648|uniprotkb:P17135|uniprotkb:Q0D2Q5|uniprotkb:B3KVR1 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:rsmn_human(display_long)|uniprotkb:Tissue-specific-splicing protein(gene name synonym)|uniprotkb:SNRPN(gene name)|psi-mi:SNRPN(display_short)|uniprotkb:HCERN3(gene name synonym)|uniprotkb:SMN(gene name synonym)|uniprotkb:Sm protein N(gene name synonym)|uniprotkb:Sm protein D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252240|imex:IM-24135-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) ensembl:ENST00000346403(transcript)|ensembl:ENST00000390687(transcript)|ensembl:ENST00000400097(transcript)|ensembl:ENST00000400100(transcript)|ensembl:ENST00000577565(transcript)|ensembl:ENST00000642807(transcript)|ensembl:ENST00000645002(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|ensembl:ENSG00000128739(gene)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P63162|rcsb pdb:5MF9|reactome:R-HSA-72163|go:"GO:0009725"(response to hormone)|refseq:NP_003088.1|refseq:NP_073716.1|refseq:NP_073717.1|refseq:NP_073718.1|refseq:NP_073719.1|refseq:NP_005669.2|entrezgene/locuslink:6638(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:F839ujOi+/hObAvs2L3Majys3E09606 rigid:j4fjQeclIQZO5GduUm86uw3kqRg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NWB1-5 uniprotkb:P63162 intact:EBI-12123390|ensembl:ENSP00000347855 intact:EBI-712493|ensembl:ENSP00000463458|ensembl:ENSP00000494831|ensembl:ENSP00000495345|ensembl:ENSP00000306223|ensembl:ENSP00000375105|ensembl:ENSP00000382969|ensembl:ENSP00000382972|uniprotkb:P14648|uniprotkb:P17135|uniprotkb:Q0D2Q5|uniprotkb:B3KVR1 psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:rsmn_human(display_long)|uniprotkb:Tissue-specific-splicing protein(gene name synonym)|uniprotkb:SNRPN(gene name)|psi-mi:SNRPN(display_short)|uniprotkb:HCERN3(gene name synonym)|uniprotkb:SMN(gene name synonym)|uniprotkb:Sm protein N(gene name synonym)|uniprotkb:Sm protein D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252232|imex:IM-24135-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) ensembl:ENST00000346403(transcript)|ensembl:ENST00000390687(transcript)|ensembl:ENST00000400097(transcript)|ensembl:ENST00000400100(transcript)|ensembl:ENST00000577565(transcript)|ensembl:ENST00000642807(transcript)|ensembl:ENST00000645002(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|ensembl:ENSG00000128739(gene)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P63162|rcsb pdb:5MF9|reactome:R-HSA-72163|go:"GO:0009725"(response to hormone)|refseq:NP_003088.1|refseq:NP_073716.1|refseq:NP_073717.1|refseq:NP_073718.1|refseq:NP_073719.1|refseq:NP_005669.2|entrezgene/locuslink:6638(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rogid:F839ujOi+/hObAvs2L3Majys3E09606 rigid:GtenzW5iy9J/OsU8uFV8Qn+XN/M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15173 uniprotkb:Q99719 intact:EBI-3906629|uniprotkb:Q53XW6|ensembl:ENSP00000241651 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:myog_human(display_long)|uniprotkb:MYOG(gene name)|psi-mi:MYOG(display_short)|uniprotkb:BHLHC3(gene name synonym)|uniprotkb:MYF4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Myogenic factor 4(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252224|imex:IM-24135-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002470.2|ensembl:ENSG00000122180(gene)|ensembl:ENST00000241651(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009629"(response to gravity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0071259"(cellular response to magnetism)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|dip:DIP-159N|entrezgene/locuslink:4656(identity) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) - - crc64:47054765DEA10D33 figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:7r8zPLBvho1GRHTAr7SVXjDXRxg9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:0udwVBmJ2ID/JPPYPIEtk4XC3dQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43356 uniprotkb:Q99719 intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252216|imex:IM-24135-1151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) - - crc64:47054765DEA10D33 figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:nQySRlWcBtXeWSPVfRgAT7Ohjis false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14141 uniprotkb:Q99719 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252208|imex:IM-24135-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N|entrezgene/locuslink:23157(identity) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) - - crc64:47054765DEA10D33 figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:onUUjwC+FyLQWnGgnvyVM+sdkJU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99719 uniprotkb:Q99719 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252200|imex:IM-24135-967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) - crc64:47054765DEA10D33 crc64:47054765DEA10D33 figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:cpkRfjCeTzX0jL8j29z1Y9CxL3s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15019-3 uniprotkb:Q99719 intact:EBI-11525407|ensembl:ENSP00000385109 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:q15019-3(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252192|imex:IM-24135-965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000401990(transcript)|ensembl:ENSG00000168385(gene)|intact:EBI-741220(isoform-parent)|uniprotkb:Q15019-3(isoform-parent)|entrezgene/locuslink:4735(identity) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) - isoform-comment:No experimental confirmation available. crc64:47054765DEA10D33 figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fBY0oYn+bn7aJbJr9OyZEpqkhLc9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:2mXbU3ff2KFrcNM2euQ5BFJmad0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WYJ6 uniprotkb:Q99719 intact:EBI-693002|uniprotkb:B4DVE6|uniprotkb:Q658T1|uniprotkb:Q8NEZ1|uniprotkb:Q96EL4|uniprotkb:Q9H285|ensembl:ENSP00000498586 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept1_human(display_long)|uniprotkb:SEPTIN1(gene name)|psi-mi:SEPTIN1(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:LARP(gene name synonym)|uniprotkb:PNUTL3(gene name synonym)|uniprotkb:Peanut-like protein 3(gene name synonym)|uniprotkb:SEPT1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-24(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252184|imex:IM-24135-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443070.5|ensembl:ENSG00000180096(gene)|ensembl:ENST00000652617(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005940"(septin ring)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051311"(meiotic metaphase plate congression)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0072687"(meiotic spindle)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6WBE|entrezgene/locuslink:1731(identity) refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N|entrezgene/locuslink:5413(identity) - - crc64:47054765DEA10D33 figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2021/06/18 rogid:hw4il5ccV1YaEnJv0uROFaeKElE9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:JQpcBNeebinGxys+Dq4FMBUQZSI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N9N5-2 uniprotkb:Q9UJD0 intact:EBI-11524452|ensembl:ENSP00000347125 intact:EBI-3909436|ensembl:ENSP00000361768|ensembl:ENSP00000361769|uniprotkb:D3DPV8|uniprotkb:Q92511|uniprotkb:X5D7U7 psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym) psi-mi:rims3_human(display_long)|uniprotkb:RIMS3(gene name)|psi-mi:RIMS3(display_short)|uniprotkb:KIAA0237(gene name synonym)|uniprotkb:RIM3 gamma(gene name synonym)|uniprotkb:Rab-3-interacting molecule 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252176|imex:IM-24135-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity) ensembl:ENSG00000117016(gene)|ensembl:ENST00000372683(transcript)|ensembl:ENST00000372684(transcript)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR039032|refseq:NP_055562.2|entrezgene/locuslink:9783(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606 rogid:NblGKOuN12f+mXOrdc//beoOPQ09606 rigid:olrNCWBFU7kcZVLKETQrhuYqUWs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N9N5-2 uniprotkb:Q9UJD0-2 intact:EBI-11524452|ensembl:ENSP00000347125 intact:EBI-21252162 psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym) psi-mi:q9ujd02(display_long)|uniprotkb:RIMS3(gene name)|psi-mi:RIMS3(display_short)|uniprotkb:KIAA0237(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252168|imex:IM-24135-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity) uniprotkb:Q9UJD0-2(isoform-parent)|entrezgene/locuslink:9783(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606 rogid:/0eiIHVaD2srQs1XbR8OdY29AoQ9606 rigid:pu1g0P2FIt8QbwturRvIZf5lpOM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75152 uniprotkb:X5D7N4 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 intact:EBI-21252118 psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:x5d7n4_human(display_long)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252154|imex:IM-24135-1149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|entrezgene/locuslink:9877(identity) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|refseq:XP_005246303.1|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR019804|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR036964|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 rogid:hoCSdc5ri+E93yLeocriDHGGBUo9606 rigid:vausek7t3sUBpW4ppUaC45y1Z18 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MC5 uniprotkb:X5D7N4 intact:EBI-718468|uniprotkb:O00223|uniprotkb:O75769|uniprotkb:Q8IZ36|uniprotkb:Q96H25|ensembl:ENSP00000300006|ensembl:ENSP00000483858 intact:EBI-21252118 psi-mi:merb1_human(display_long)|uniprotkb:BMERB1(gene name)|psi-mi:BMERB1(display_short)|uniprotkb:C16orf45(gene name synonym) psi-mi:x5d7n4_human(display_long)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252146|imex:IM-24135-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135941.1|refseq:NP_149978.1|ensembl:ENSG00000166780(gene)|ensembl:ENSG00000278823(gene)|ensembl:ENST00000300006(transcript)|ensembl:ENST00000615273(transcript)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021822"(negative regulation of cell motility involved in cerebral cortex radial glia guided migration)|interpro:IPR022735|interpro:IPR040127|entrezgene/locuslink:89927(identity) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|refseq:XP_005246303.1|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR019804|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR036964|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:DSzrN8rIE3sJnAJeI9Bg9GuhClg9606 rogid:hoCSdc5ri+E93yLeocriDHGGBUo9606 rigid:svJETsLNLiumc8VVEy089m+8dxM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D7N4 intact:EBI-21247765 intact:EBI-21252118 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7n4_human(display_long)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252138|imex:IM-24135-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|refseq:XP_005246303.1|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR019804|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR036964|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:hoCSdc5ri+E93yLeocriDHGGBUo9606 rigid:PW+PDuCY81huDeTV6zOhslyuGP4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75152 uniprotkb:Q8WZA2 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252110|imex:IM-24135-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|entrezgene/locuslink:9877(identity) refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 rigid:TIwdeL6GV19GPgzF2nkcdc2197s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:Q8WZA2 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252102|imex:IM-24135-963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 rigid:Xm9kiChfe4ung+BbeL8YL0NJTEE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UH65 uniprotkb:Q8WZA2 intact:EBI-310749|uniprotkb:O75135|uniprotkb:Q7LCY6|uniprotkb:Q9P061|uniprotkb:Q9P0Z8|uniprotkb:D3DQV1|ensembl:ENSP00000315630 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:swp70_human(display_long)|uniprotkb:KIAA0640(gene name synonym)|uniprotkb:SWAP70(gene name)|psi-mi:SWAP70(display_short)|uniprotkb:HSPC321(orf name) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252094|imex:IM-24135-1147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055870.2|refseq:NP_001284643.1|go:"GO:0060754"(positive regulation of mast cell chemotaxis)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2DN6|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000133789(gene)|ensembl:ENST00000318950(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033633"(negative regulation of cell-cell adhesion mediated by integrin)|go:"GO:0045190"(isotype switching)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|entrezgene/locuslink:23075(identity) refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:GU1JyBHhrTRPDnzRBSIJeP8d4ZE9606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 rigid:vcL/gHE9TI/FYhTZWyGeVdd1Lcc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MC5 uniprotkb:Q8WZA2 intact:EBI-718468|uniprotkb:O00223|uniprotkb:O75769|uniprotkb:Q8IZ36|uniprotkb:Q96H25|ensembl:ENSP00000300006|ensembl:ENSP00000483858 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:merb1_human(display_long)|uniprotkb:BMERB1(gene name)|psi-mi:BMERB1(display_short)|uniprotkb:C16orf45(gene name synonym) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252086|imex:IM-24135-961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135941.1|refseq:NP_149978.1|ensembl:ENSG00000166780(gene)|ensembl:ENSG00000278823(gene)|ensembl:ENST00000300006(transcript)|ensembl:ENST00000615273(transcript)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021822"(negative regulation of cell motility involved in cerebral cortex radial glia guided migration)|interpro:IPR022735|interpro:IPR040127|entrezgene/locuslink:89927(identity) refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:DSzrN8rIE3sJnAJeI9Bg9GuhClg9606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 rigid:JFZN38xMUPSuZvRRtY0s4EuXjt4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:Q8WZA2 intact:EBI-21247765 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252078|imex:IM-24135-959 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1|entrezgene/locuslink:11069(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 rigid:fs5oyOdSsG+Dnz+WDvzR0REvsf8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z3S9 uniprotkb:Q15274 intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929 intact:EBI-739851|uniprotkb:Q53XW7|uniprotkb:Q96G22|uniprotkb:Q9BSG6|ensembl:ENSP00000378782|ensembl:ENSP00000404873 psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym) psi-mi:nadc_human(display_long)|uniprotkb:QPRT(gene name)|psi-mi:QPRT(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252070|imex:IM-24135-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9|entrezgene/locuslink:388677(identity) refseq:NP_055113.2|refseq:NP_001305178.1|refseq:NP_001305179.1|ensembl:ENSG00000103485(gene)|ensembl:ENST00000395384(transcript)|ensembl:ENST00000449759(transcript)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034213"(quinolinate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022412|interpro:IPR027277|interpro:IPR036068|interpro:IPR037128|rcsb pdb:2JBM|rcsb pdb:4KWV|rcsb pdb:4KWW|rcsb pdb:5AYX|rcsb pdb:5AYY|rcsb pdb:5AYZ|reactome:R-HSA-196807|entrezgene/locuslink:23475(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606 rogid:ayjZsjJprp+eirEIN5VqDHmIzoA9606 rigid:W8kLWvHHixOFTrEE4FFzFOXVlKA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14936-4 uniprotkb:P35354 intact:EBI-12007726|ensembl:ENSP00000495291 intact:EBI-6662113|ensembl:ENSP00000356438|ensembl:ENSP00000506242|uniprotkb:A8K802|uniprotkb:Q16876 psi-mi:o14936-4(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym) psi-mi:pgh2_human(display_long)|uniprotkb:PTGS2(gene name)|psi-mi:PTGS2(display_short)|uniprotkb:COX2(gene name synonym)|uniprotkb:Cyclooxygenase-2(gene name synonym)|uniprotkb:PHS II(gene name synonym)|uniprotkb:Prostaglandin H2 synthase 2(gene name synonym)|uniprotkb:Prostaglandin-endoperoxide synthase 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252062|imex:IM-24135-957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1215506(isoform-parent)|uniprotkb:O14936-4(isoform-parent)|ensembl:ENSG00000147044(gene)|ensembl:ENST00000646120(transcript)|entrezgene/locuslink:8573(identity) ensembl:ENSG00000073756(gene)|ensembl:ENST00000367468(transcript)|ensembl:ENST00000680451(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001525"(angiogenesis)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004666"(prostaglandin-endoperoxide synthase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005901"(caveola)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007566"(embryo implantation)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0030728"(ovulation)|go:"GO:0007613"(memory)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031622"(positive regulation of fever generation)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033280"(response to vitamin D)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042633"(hair cycle)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0009750"(response to fructose)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010042"(response to manganese ion)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0010226"(response to lithium ion)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046697"(decidualization)|go:"GO:0046872"(metal ion binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0090362"(positive regulation of platelet-derived growth factor production)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029576|interpro:IPR037120|rcsb pdb:1V0X|rcsb pdb:5F19|rcsb pdb:5F1A|rcsb pdb:5IKQ|rcsb pdb:5IKR|go:"GO:0070542"(response to fatty acid)|rcsb pdb:5IKT|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071284"(cellular response to lead ion)|rcsb pdb:5IKV|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071456"(cellular response to hypoxia)|rcsb pdb:5KIR|reactome:R-HSA-197264|reactome:R-HSA-2142770|go:"GO:0071471"(cellular response to non-ionic osmotic stress)|reactome:R-HSA-2162123|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-9018677|reactome:R-HSA-9018679|reactome:R-HSA-9025094|reactome:R-HSA-9027604|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:NP_000954.1|dip:DIP-28131N|entrezgene/locuslink:5743(identity) - isoform-comment:Contains a phosphoserine at position 577. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wPk2DtY0JCvGelwtsIEz1Vdvo0w9606 rogid:WGHtPKMIVOhbG4HdzQyqaBTUH509606 rigid:qZuBXhhopdreV+kpILDXC95JDHQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A0C4DGF1 uniprotkb:O43741 intact:EBI-10188476|ensembl:ENSP00000433657 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252054|imex:IM-24135-1145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:pDXmOoXyRPmuoPJaBES72uJnmyU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T124-6 uniprotkb:O43741 intact:EBI-11524408 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252046|imex:IM-24135-955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:2468YljvZ9eolGNuLsGZY57g1Mw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UDY6-2 uniprotkb:O43741 intact:EBI-11981577|ensembl:ENSP00000259941|ensembl:ENSP00000365894|ensembl:ENSP00000393576|ensembl:ENSP00000393787|ensembl:ENSP00000393976|ensembl:ENSP00000398404|ensembl:ENSP00000405578|ensembl:ENSP00000412370 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q9udy6-2(display_long)|uniprotkb:TRIM10(gene name)|psi-mi:TRIM10(display_short)|uniprotkb:B30-RING finger protein(gene name synonym)|uniprotkb:RFB30(gene name synonym)|uniprotkb:RING finger protein 9(gene name synonym)|uniprotkb:RNF9(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252038|imex:IM-24135-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6427325(isoform-parent)|ensembl:ENSG00000137394(gene)|ensembl:ENSG00000227472(gene)|ensembl:ENSG00000229346(gene)|ensembl:ENSG00000229381(gene)|ensembl:ENSG00000235025(gene)|ensembl:ENSG00000237192(gene)|ensembl:ENSG00000237703(gene)|ensembl:ENST00000259941(transcript)|ensembl:ENST00000376704(transcript)|ensembl:ENST00000413055(transcript)|ensembl:ENST00000416714(transcript)|ensembl:ENST00000417411(transcript)|ensembl:ENST00000428611(transcript)|ensembl:ENST00000446013(transcript)|ensembl:ENST00000447465(transcript)|ensembl:ENSG00000204613(gene)|uniprotkb:Q9UDY6-2(isoform-parent)|entrezgene/locuslink:10107(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - isoform-comment:"Ref.2 (AAG53496) sequence is in conflict in position: 379:C->G." - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XJ28kipA0buHA9aIm6kFPCmnGmE9606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:hftdyhHqVn61/Kfea5tPC9vtKhI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12933 uniprotkb:O43741 intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252030|imex:IM-24135-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:Um1zwcKSpcWm8QYZKlLLbl9TWbQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05BL1 uniprotkb:O43741 intact:EBI-11952721|intact:EBI-12700013 intact:EBI-1053424|uniprotkb:Q5VXY0|uniprotkb:B4DH06|uniprotkb:A8K9V5|ensembl:ENSP00000254101 psi-mi:q05bl1_human(display_long)|uniprotkb:TP53BP2(gene name)|psi-mi:TP53BP2(display_short) psi-mi:aakb2_human(display_long)|uniprotkb:PRKAB2(gene name)|psi-mi:PRKAB2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252022|imex:IM-24135-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|entrezgene/locuslink:7159(identity) refseq:NP_005390.1|ensembl:ENSG00000131791(gene)|ensembl:ENST00000254101(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:O43741|rcsb pdb:2F15|rcsb pdb:2V8Q|rcsb pdb:2V92|rcsb pdb:2V9J|rcsb pdb:2Y8L|rcsb pdb:2Y8Q|rcsb pdb:2YA3|rcsb pdb:4CFH|rcsb pdb:4EAI|rcsb pdb:4EAJ|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:6B2E|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|interpro:IPR014756(Immunoglobulin E-set)|dip:DIP-39763N|entrezgene/locuslink:5565(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:LA1UvPUs8vUyy7hDTxjj8DevaY89606 rogid:GYLp/VWkcEC1mJcrg0gtIQ99DVg9606 rigid:G3BVIUA1SOET18OPGliWPTHw7hA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O00161 uniprotkb:Q16623 intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252264|imex:IM-24135-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974|entrezgene/locuslink:8773(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:3OxQ4U/Fd4BNQ+w0/PVwEJC0qME false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95721 uniprotkb:Q16623 intact:EBI-490676|ensembl:ENSP00000215730 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252272|imex:IM-24135-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004773.1|ensembl:ENSG00000099940(gene)|ensembl:ENST00000215730(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019905"(syntaxin binding)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061025"(membrane fusion)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|dip:DIP-56475N|entrezgene/locuslink:9342(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:HU/6Pfj5lstRDWi2rEKaTtQK4LE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16623 uniprotkb:Q16623 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252280|imex:IM-24135-755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:czSHeXHxTXkhaktEx381T06k/IE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G2XKQ0 uniprotkb:Q16623 intact:EBI-10175576|intact:EBI-11748457|intact:EBI-12696778 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:sumo5_human(display_long)|uniprotkb:SUMO1P1(gene name)|psi-mi:SUMO1P1(display_short)|uniprotkb:SUMO1 pseudogene 1(gene name synonym)|uniprotkb:SUMO5(gene name synonym)|uniprotkb:UBL2(gene name synonym)|uniprotkb:UBL6(gene name synonym)|uniprotkb:Ubiquitin-like 2(gene name synonym)|uniprotkb:Ubiquitin-like 6(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252288|imex:IM-24135-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6IAM|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|go:"GO:0005634"(nucleus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030578"(PML body organization)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0008134"(transcription factor binding)|entrezgene/locuslink:391257(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:11wHcQsr2mX9H/1yO550wkO0UKo9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:hw17kpQAVa2AnDZsCx9jPowH33w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40222 uniprotkb:Q16623 intact:EBI-359793|uniprotkb:Q5TFJ6|uniprotkb:Q66K62|uniprotkb:Q86T54|uniprotkb:Q86T85|uniprotkb:Q86T86|uniprotkb:Q86Y86|uniprotkb:Q86YW3|uniprotkb:Q8N2Y3|uniprotkb:D3DPP6|ensembl:ENSP00000362711|ensembl:ENSP00000362712 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:txlna_human(display_long)|uniprotkb:TXLNA(gene name)|psi-mi:TXLNA(display_short)|uniprotkb:TXLN(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252296|imex:IM-24135-1323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_787048.1|ensembl:ENSG00000084652(gene)|ensembl:ENST00000373609(transcript)|ensembl:ENST00000373610(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0042113"(B cell activation)|interpro:IPR026183|reactome:R-HSA-449836|refseq:XP_016856051.1|dip:DIP-27612N|entrezgene/locuslink:200081(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:m6McBNTQ5VY4RNUY6PyYTj97YUk9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:DGN6v2rIIxQUppT7hN7QMbGjRBo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N3L3 uniprotkb:Q16623 intact:EBI-6116822|intact:EBI-10173842|uniprotkb:Q5HYH7|uniprotkb:Q5VTF3|uniprotkb:Q76L25|uniprotkb:Q86T52|uniprotkb:Q8N3S2|ensembl:ENSP00000351206 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:txlnb_human(display_long)|uniprotkb:TXLNB(gene name)|psi-mi:TXLNB(display_short)|uniprotkb:C6orf198(gene name synonym)|uniprotkb:MDP77(gene name synonym)|uniprotkb:Muscle-derived protein 77(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252304|imex:IM-24135-969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011533807.1|refseq:XP_005266893.1|refseq:NP_694967.3|refseq:XP_016865811.1|ensembl:ENSG00000164440(gene)|ensembl:ENST00000358430(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0019905"(syntaxin binding)|interpro:IPR026183|entrezgene/locuslink:167838(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VvnbZ6DG0XltABogRKOW1drEBCQ9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:BN076sQLJxnppa//PvqAfDx13rA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:Q05086-3 intact:EBI-16439278 intact:EBI-11026619|ensembl:ENSP00000490258|ensembl:ENSP00000497572 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:q05086-3(display_long)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252571|imex:IM-24135-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) ensembl:ENSG00000114062(gene)|ensembl:ENST00000637886(transcript)|ensembl:ENST00000648336(transcript)|intact:EBI-954357(isoform-parent)|uniprotkb:Q05086-3(isoform-parent)|entrezgene/locuslink:7337(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:joMSLIl290tAZwoEGpYGfprWf589606 rigid:dokUyz1pWAR1fRz/GGcNaWWHirI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43361 uniprotkb:Q05086-3 intact:EBI-10182930|uniprotkb:Q9BUN9|intact:EBI-28989087|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776 intact:EBI-11026619|ensembl:ENSP00000490258|ensembl:ENSP00000497572 psi-mi:maga8_human(display_long)|uniprotkb:MAGEA8(gene name)|psi-mi:MAGEA8(display_short)|uniprotkb:Cancer/testis antigen 1.8(gene name synonym)|uniprotkb:MAGE-8 antigen(gene name synonym)|uniprotkb:MAGE8(gene name synonym) psi-mi:q05086-3(display_long)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252563|imex:IM-24135-1159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159872.1|refseq:NP_001159873.1|refseq:NP_005355.2|refseq:XP_016885009.1|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776|ensembl:ENSG00000156009(gene)|ensembl:ENST00000286482(transcript)|ensembl:ENST00000535454(transcript)|ensembl:ENST00000542674(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030095|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4107(identity) ensembl:ENSG00000114062(gene)|ensembl:ENST00000637886(transcript)|ensembl:ENST00000648336(transcript)|intact:EBI-954357(isoform-parent)|uniprotkb:Q05086-3(isoform-parent)|entrezgene/locuslink:7337(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Qz29eM5nzFfUZl/DBtBcdhGQBNE9606 rogid:joMSLIl290tAZwoEGpYGfprWf589606 rigid:Md7mWdOsTgMFTYfy3UOmewHwkh4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NA61-2 uniprotkb:X5DRC8 intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148 intact:EBI-21252534 psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym) psi-mi:x5drc8_human(display_long)|uniprotkb:TSC2(gene name)|psi-mi:TSC2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252555|imex:IM-24135-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity) go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003913(Tuberin)|interpro:IPR018515|interpro:IPR027107|interpro:IPR024584|entrezgene/locuslink:7249(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606 rogid:4xtsHw1M2TN9aXXcCO0yMQhroEo9606 rigid:2rLvoFzAd/b1FLTiMz5EbHNMZb8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:X5DRC8 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-21252534 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:x5drc8_human(display_long)|uniprotkb:TSC2(gene name)|psi-mi:TSC2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252547|imex:IM-24135-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity) go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003913(Tuberin)|interpro:IPR018515|interpro:IPR027107|interpro:IPR024584|entrezgene/locuslink:7249(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:4xtsHw1M2TN9aXXcCO0yMQhroEo9606 rigid:c7bqPGaGFqJgyTv7HlX3kyj2rww false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48775 uniprotkb:P48775 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252526|imex:IM-24135-1157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:AshC+Zvuy75AfbJKJJZ6JFNIjYY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O00560 uniprotkb:P48775 intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252518|imex:IM-24135-977 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N|entrezgene/locuslink:6386(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:vDL5NdcEXdI/ZK9UHlmTNHe0xiU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04864-2 uniprotkb:P48775 intact:EBI-10829018|ensembl:ENSP00000377989 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:q04864-2(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252510|imex:IM-24135-1325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162924(gene)|ensembl:ENST00000394479(transcript)|intact:EBI-307352(isoform-parent)|uniprotkb:Q04864-2(isoform-parent)|entrezgene/locuslink:5966(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:8siR4qQAj7RdqB2Lmy8maiEO/349606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:D3ZDG4F0m9jdlqbDXVbpwwkF9P4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HAN9 uniprotkb:P48775 intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252502|imex:IM-24135-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:A3vwI3WydyvsxXm0ireTvlaYxjs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:P48775 intact:EBI-16439278 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252494|imex:IM-24135-759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:aiygSP/gaDJsECrKMq41L0b6DKE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95671 uniprotkb:P48775 intact:EBI-743231|ensembl:ENSP00000370718|uniprotkb:Q5JQ53|uniprotkb:Q8NBH5|uniprotkb:Q96G02|uniprotkb:Q9BUL6|uniprotkb:J3JS33|uniprotkb:B4DX75|uniprotkb:F5GXH4 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:asml_human(display_long)|uniprotkb:ASMTL(gene name)|psi-mi:ASMTL(display_short) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252486|imex:IM-24135-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001166944.1|ensembl:ENSG00000169093(gene)|ensembl:ENST00000381317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0032259"(methylation)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0036221"(UTP diphosphatase activity)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|interpro:IPR001077(O-methyltransferase, family 2)|interpro:IPR003697(Maf-like protein)|interpro:IPR016461(O-methyltransferase, COMT, eukaryota)|interpro:IPR029001|interpro:IPR029063|interpro:IPR031725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2P5X|rcsb pdb:6XI4|rcsb pdb:6XI5|refseq:NP_001166945.1|refseq:NP_004183.2|refseq:XP_005274491.1|refseq:XP_005274840.1|entrezgene/locuslink:8623(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:AVFt1UIMxAp+zMcGUgHje7j0yZI9606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:fBw51rxXxRoMIM2e8xFFpjUvZ0g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94842 uniprotkb:O95947 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 intact:EBI-2824328|ensembl:ENSP00000279386|ensembl:ENSP00000378650|intact:EBI-8485506|intact:MINT-6772404|uniprotkb:Q8TAS4|uniprotkb:Q9HA44 psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:tbx6_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252478|imex:IM-24135-975 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1|entrezgene/locuslink:9878(identity) refseq:XP_011544228.1|refseq:XP_016879103.1|ensembl:ENSG00000149922(gene)|ensembl:ENST00000279386(transcript)|ensembl:ENST00000395224(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0000785"(chromatin)|go:"GO:0001947"(heart looping)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:O95947|refseq:NP_004599.2|refseq:XP_005255580.1|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rogid:AUtp41W3xaJIsOQ0XR5Tyezl3mo9606 rigid:XRqfWQFizARs+7eifEbPILzVzac false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:O95947 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-2824328|ensembl:ENSP00000279386|ensembl:ENSP00000378650|intact:EBI-8485506|intact:MINT-6772404|uniprotkb:Q8TAS4|uniprotkb:Q9HA44 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:tbx6_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252470|imex:IM-24135-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) refseq:XP_011544228.1|refseq:XP_016879103.1|ensembl:ENSG00000149922(gene)|ensembl:ENST00000279386(transcript)|ensembl:ENST00000395224(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0000785"(chromatin)|go:"GO:0001947"(heart looping)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:O95947|refseq:NP_004599.2|refseq:XP_005255580.1|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:AUtp41W3xaJIsOQ0XR5Tyezl3mo9606 rigid:ZVPft8q5e6qRUnG7XchjemdFLYY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96LI6 uniprotkb:O95947 intact:EBI-3957665|uniprotkb:Q17RC0|uniprotkb:Q7Z4L8|uniprotkb:Q9BZA2|uniprotkb:Q9BZA3|ensembl:ENSP00000303599|ensembl:ENSP00000306549 intact:EBI-2824328|ensembl:ENSP00000279386|ensembl:ENSP00000378650|intact:EBI-8485506|intact:MINT-6772404|uniprotkb:Q8TAS4|uniprotkb:Q9HA44 psi-mi:hsfy1_human(display_long)|uniprotkb:HSFY1(gene name)|psi-mi:HSFY1(display_short)|uniprotkb:HSFY2(gene name)|psi-mi:HSFY2(display_short)|uniprotkb:HSF2L(gene name synonym)|uniprotkb:HSFY(gene name synonym)|uniprotkb:Heat shock transcription factor 2-like protein(gene name synonym) psi-mi:tbx6_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252462|imex:IM-24135-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001877.1|refseq:NP_149099.2|refseq:NP_689797.1|refseq:NP_714927.1|ensembl:ENSG00000169953(gene)|ensembl:ENSG00000172468(gene)|ensembl:ENST00000304790(transcript)|ensembl:ENST00000307393(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR027730|interpro:IPR036388|interpro:IPR036390|refseq:XP_016885520.1|entrezgene/locuslink:86614(identity) refseq:XP_011544228.1|refseq:XP_016879103.1|ensembl:ENSG00000149922(gene)|ensembl:ENST00000279386(transcript)|ensembl:ENST00000395224(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0000785"(chromatin)|go:"GO:0001947"(heart looping)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:O95947|refseq:NP_004599.2|refseq:XP_005255580.1|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:grGh9Q0MUaspNXflIH6A5orHPEs9606 rogid:AUtp41W3xaJIsOQ0XR5Tyezl3mo9606 rigid:Sz+Ju6GQLMAYfmu6hhLUxWl1zb4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P1W5 uniprotkb:O95947 intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76 intact:EBI-2824328|ensembl:ENSP00000279386|ensembl:ENSP00000378650|intact:EBI-8485506|intact:MINT-6772404|uniprotkb:Q8TAS4|uniprotkb:Q9HA44 psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short) psi-mi:tbx6_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252452|imex:IM-24135-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity) refseq:XP_011544228.1|refseq:XP_016879103.1|ensembl:ENSG00000149922(gene)|ensembl:ENST00000279386(transcript)|ensembl:ENST00000395224(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0000785"(chromatin)|go:"GO:0001947"(heart looping)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:O95947|refseq:NP_004599.2|refseq:XP_005255580.1|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606 rogid:AUtp41W3xaJIsOQ0XR5Tyezl3mo9606 rigid:2NCR88w89qokVDwLkTBz+jp9JRY false sufficient binding region:191-598 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:X5DP27 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-21252424 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:x5dp27_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252444|imex:IM-24135-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:HvFBQ4CCCyAxjMPMTMhO8Dzwg8E9606 rigid:QcHFGHsYaegqgFSB4BgjBpCVIrI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:X5DP27 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-21252424 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:x5dp27_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252436|imex:IM-24135-1155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:HvFBQ4CCCyAxjMPMTMhO8Dzwg8E9606 rigid:XwFzq19PPecwBBW/mehD0Sn6dzw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93062-3 uniprotkb:X5D304 intact:EBI-740343|ensembl:ENSP00000340176 intact:EBI-21252397 psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:x5d304_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252416|imex:IM-24135-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR036960|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606 rogid:7WaIKDgYB8Vzoywvn1C7C6uKv949606 rigid:+vrZK0O09JB9XCi9UFR7F3NJWXU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6FHY5 uniprotkb:X5D304 intact:EBI-16439278 intact:EBI-21252397 psi-mi:q6fhy5_human(display_long)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short) psi-mi:x5d304_human(display_long)|uniprotkb:TBX6(gene name)|psi-mi:TBX6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252408|imex:IM-24135-973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|interpro:IPR042634|entrezgene/locuslink:4223(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR036960|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|entrezgene/locuslink:6911(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1YE6tvnIb7ZIF3P7OAZfhMWwxxI9606 rogid:7WaIKDgYB8Vzoywvn1C7C6uKv949606 rigid:wyd68KZEU/PkSmuB1IXaczQnRZA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96PM5-4 uniprotkb:Q9UL54 intact:EBI-21252376 intact:EBI-352832|ensembl:ENSP00000310094|uniprotkb:O94957|uniprotkb:Q6UW73|uniprotkb:Q7LC09|uniprotkb:Q9NSW2|uniprotkb:B2RN35|uniprotkb:A5PKY1|uniprotkb:A7MCZ2|uniprotkb:B7ZM88 psi-mi:q96pm54(display_long)|uniprotkb:RCHY1(gene name)|psi-mi:RCHY1(display_short)|uniprotkb:ARNIP(gene name synonym)|uniprotkb:CHIMP(gene name synonym)|uniprotkb:PIRH2(gene name synonym)|uniprotkb:RNF199(gene name synonym)|uniprotkb:ZNF363(gene name synonym)|uniprotkb:Pirh2b(isoform synonym) psi-mi:taok2_human(display_long)|uniprotkb:TAOK2(gene name)|psi-mi:TAOK2(display_short)|uniprotkb:KIAA0881(gene name synonym)|uniprotkb:MAP3K17(gene name synonym)|uniprotkb:PSK(gene name synonym)|uniprotkb:PSK1(gene name synonym)|uniprotkb:UNQ2971/PRO7431(orf name)|uniprotkb:Prostate-derived sterile 20-like kinase 1(gene name synonym)|uniprotkb:Thousand and one amino acid protein kinase 2(gene name synonym)|uniprotkb:Kinase from chicken homolog C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252387|imex:IM-24135-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q96PM5-4(isoform-parent)|entrezgene/locuslink:25898(identity) go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038191"(neuropilin binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0048156"(tau protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0106311"|go:"GO:0150019"(basal dendrite morphogenesis)|go:"GO:0150020"(basal dendrite arborization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0044295"(axonal growth cone)|mint:Q9UL54|go:"GO:0046330"(positive regulation of JNK cascade)|ensembl:ENSG00000149930(gene)|ensembl:ENST00000308893(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|refseq:NP_004774.1|refseq:NP_057235.2|refseq:NP_001238972.1|entrezgene/locuslink:9344(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:sIIDQJZ1NaDNRJij//kojlGIDjM9606 rogid:aA9reWZMb8l6Ziy+jyX5bbTD6vE9606 rigid:2P0vaKJ3AiJak1zYguNdeEtevIo false sufficient binding region:1-170 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q53G59 uniprotkb:Q9UL54 intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5 intact:EBI-352832|ensembl:ENSP00000310094|uniprotkb:O94957|uniprotkb:Q6UW73|uniprotkb:Q7LC09|uniprotkb:Q9NSW2|uniprotkb:B2RN35|uniprotkb:A5PKY1|uniprotkb:A7MCZ2|uniprotkb:B7ZM88 psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym) psi-mi:taok2_human(display_long)|uniprotkb:TAOK2(gene name)|psi-mi:TAOK2(display_short)|uniprotkb:KIAA0881(gene name synonym)|uniprotkb:MAP3K17(gene name synonym)|uniprotkb:PSK(gene name synonym)|uniprotkb:PSK1(gene name synonym)|uniprotkb:UNQ2971/PRO7431(orf name)|uniprotkb:Prostate-derived sterile 20-like kinase 1(gene name synonym)|uniprotkb:Thousand and one amino acid protein kinase 2(gene name synonym)|uniprotkb:Kinase from chicken homolog C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252368|imex:IM-24135-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity) go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038191"(neuropilin binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0048156"(tau protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0106311"|go:"GO:0150019"(basal dendrite morphogenesis)|go:"GO:0150020"(basal dendrite arborization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0044295"(axonal growth cone)|mint:Q9UL54|go:"GO:0046330"(positive regulation of JNK cascade)|ensembl:ENSG00000149930(gene)|ensembl:ENST00000308893(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|refseq:NP_004774.1|refseq:NP_057235.2|refseq:NP_001238972.1|entrezgene/locuslink:9344(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606 rogid:aA9reWZMb8l6Ziy+jyX5bbTD6vE9606 rigid:CT+G6bpTRQrCSvzlpCsoiu0RIt0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95183 uniprotkb:X5D7S1 intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647 intact:EBI-21252312 psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name) psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252360|imex:IM-24135-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855|entrezgene/locuslink:10791(identity) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rigid:UQyU/X5p3rEaIq+WcREty+8eZHo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7S1 uniprotkb:X5D7S1 intact:EBI-21252312 intact:EBI-21252312 psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252352|imex:IM-24135-971 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rigid:upuiYsW2HKUQjHUBv6fxKOXtUSI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95721 uniprotkb:X5D7S1 intact:EBI-490676|ensembl:ENSP00000215730 intact:EBI-21252312 psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short) psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252344|imex:IM-24135-1153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004773.1|ensembl:ENSG00000099940(gene)|ensembl:ENST00000215730(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019905"(syntaxin binding)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061025"(membrane fusion)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|dip:DIP-56475N|entrezgene/locuslink:9342(identity) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rigid:s9Z63lhAaWbibwGQ9aXC54WMByQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25788 uniprotkb:X5D7S1 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 intact:EBI-21252312 psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252336|imex:IM-24135-757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|entrezgene/locuslink:5684(identity) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rigid:SRGPzwgFhw67piaa90OJjsB5h1E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H115 uniprotkb:X5D7S1 intact:EBI-3921185|ensembl:ENSP00000366225|uniprotkb:Q4G187|uniprotkb:Q5JXF9|uniprotkb:Q8N3C4|uniprotkb:B4DK44|uniprotkb:Q4G0M0 intact:EBI-21252312 psi-mi:snab_human(display_long)|uniprotkb:NAPB(gene name)|psi-mi:NAPB(display_short)|uniprotkb:SNAPB(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein beta(gene name synonym) psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252328|imex:IM-24135-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125814(gene)|ensembl:ENST00000377026(transcript)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_071363.1|refseq:NP_001269947.1|refseq:NP_001269949.1|refseq:NP_001269955.1|entrezgene/locuslink:63908(identity) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:tKGtS2Dzj2CNItyIHAI2LOIiGyU9606 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rigid:sphJSrIkeZU8ve9YBHhzNak8Ifc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363 uniprotkb:X5DP20 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 intact:EBI-21248551 psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252775|imex:IM-24135-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:h8xVwLrobkcqPhFMtlvSq3tD/5s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:X5DP20 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-21248551 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252767|imex:IM-24135-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:/0EO9Ogh51P8UpW0oXDlgC+VNPU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5DP20 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21248551 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252759|imex:IM-24135-769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:4lJv2x9pweDs2Q85bZC/WCM7FC4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15409 uniprotkb:Q13363-2 intact:EBI-983612|uniprotkb:A0AUV6|uniprotkb:A4D0U8|uniprotkb:Q6ZND1|uniprotkb:Q75MJ3|uniprotkb:Q8IZE0|uniprotkb:Q8N0W2|uniprotkb:Q8N6B7|uniprotkb:Q8N6B8|uniprotkb:Q8NFQ1|uniprotkb:Q8NFQ2|uniprotkb:Q8NFQ3|uniprotkb:Q8NFQ4|uniprotkb:Q8TD74|ensembl:ENSP00000265436|ensembl:ENSP00000377132|uniprotkb:A6NNW4|uniprotkb:B4DLD9 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:foxp2_human(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252749|imex:IM-24135-989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128573(gene)|ensembl:ENST00000350908(transcript)|ensembl:ENST00000393494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021757"(caudate nucleus development)|go:"GO:0021758"(putamen development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0098582"(innate vocalization behavior)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:O15409|rcsb pdb:2A07|rcsb pdb:2AS5|go:"GO:0046872"(metal ion binding)|refseq:NP_001166237.1|refseq:NP_001166238.1|refseq:NP_055306.1|refseq:NP_683696.2|refseq:NP_683697.2|refseq:NP_683698.2|dip:DIP-29004N|refseq:XP_016868290.1|entrezgene/locuslink:93986(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - - isoform-comment:No experimental confirmation available. figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XRN9auLs2qtK6W3mjHJHAQPbO9s9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:XcZ61k6QcSP4d54fhDlyEE7fl/E false sufficient binding region:93-715 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:Q13363-2 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-10171858|ensembl:ENSP00000372411 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252741|imex:IM-24135-1333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rigid:/lCYyt7RKDZpo5fZkPo0nilnZZM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15409 uniprotkb:Q13363 intact:EBI-983612|uniprotkb:A0AUV6|uniprotkb:A4D0U8|uniprotkb:Q6ZND1|uniprotkb:Q75MJ3|uniprotkb:Q8IZE0|uniprotkb:Q8N0W2|uniprotkb:Q8N6B7|uniprotkb:Q8N6B8|uniprotkb:Q8NFQ1|uniprotkb:Q8NFQ2|uniprotkb:Q8NFQ3|uniprotkb:Q8NFQ4|uniprotkb:Q8TD74|ensembl:ENSP00000265436|ensembl:ENSP00000377132|uniprotkb:A6NNW4|uniprotkb:B4DLD9 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:foxp2_human(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252731|imex:IM-24135-1167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128573(gene)|ensembl:ENST00000350908(transcript)|ensembl:ENST00000393494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021757"(caudate nucleus development)|go:"GO:0021758"(putamen development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0098582"(innate vocalization behavior)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:O15409|rcsb pdb:2A07|rcsb pdb:2AS5|go:"GO:0046872"(metal ion binding)|refseq:NP_001166237.1|refseq:NP_001166238.1|refseq:NP_055306.1|refseq:NP_683696.2|refseq:NP_683697.2|refseq:NP_683698.2|dip:DIP-29004N|refseq:XP_016868290.1|entrezgene/locuslink:93986(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XRN9auLs2qtK6W3mjHJHAQPbO9s9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:yNVNAniDAJwwhMOYcOFa4y6eYDY false sufficient binding region:93-715 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363 uniprotkb:Q13363 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252723|imex:IM-24135-767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:QZSv8GPnDdMz9QqKYSMzyy8j9NY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14194 uniprotkb:Q14194 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6 psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252715|imex:IM-24135-987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|entrezgene/locuslink:1400(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rogid:54400VvxFWldohY2QhArAEJ23cI9606 rigid:pGRqhbTnkETW1ZgoYcW7gFyczis false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14194-2 uniprotkb:Q14194-2 intact:EBI-21248119 intact:EBI-21248119 psi-mi:q141942(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:ULIP3(gene name synonym) psi-mi:q141942(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:ULIP3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252707|imex:IM-24135-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14194-2(isoform-parent)|entrezgene/locuslink:1400(identity) uniprotkb:Q14194-2(isoform-parent)|entrezgene/locuslink:1400(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wLmx63akI7DW55pH58Se1CqI0Yc9606 rogid:wLmx63akI7DW55pH58Se1CqI0Yc9606 rigid:jFnhQly/lA5Ve2vXLlCmYzm6Ss4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:Q86UW7-2 intact:EBI-21247765 intact:EBI-21247915 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:q86uw72(display_long)|uniprotkb:CADPS2(gene name)|psi-mi:CADPS2(display_short)|uniprotkb:CAPS2(gene name synonym)|uniprotkb:KIAA1591(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252699|imex:IM-24135-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) uniprotkb:Q86UW7-2(isoform-parent)|entrezgene/locuslink:93664(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:m5P3sCgHLl4e1DrUwpYtBjote809606 rigid:v5vHvVwnpEGdjK4Y11+3oBw1eoI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7U3 uniprotkb:X5D7U3 intact:EBI-21247834 intact:EBI-21247834 psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7u3_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252691|imex:IM-24135-765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) interpro:IPR035515|interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|entrezgene/locuslink:9256(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rogid:qCjpIi41vQp/NXCfRooI4FgFj8w9606 rigid:rXhaxYLE4WQfVNR1C1GyUHjrNmA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5D2C1 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21246980 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252683|imex:IM-24135-763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:AC7I03x5GlN94ShNHGA2+NVxerc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRI5-2 uniprotkb:X5D2C1 intact:EBI-11988027|ensembl:ENSP00000355597 intact:EBI-21246980 psi-mi:q9nri5-2(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)|uniprotkb:LV(isoform synonym) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252675|imex:IM-24135-979 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-529989(isoform-parent)|ensembl:ENSG00000162946(gene)|ensembl:ENST00000366637(transcript)|uniprotkb:Q9NRI5-2(isoform-parent)|entrezgene/locuslink:27185(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - isoform-comment:Non-canonical donor and acceptor splice sites for the last 2 exons. - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XO2u/5sOZAkkn12A+INm5SA4jUY9606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:V5L7pW3g16Pg7WTMlOxb4DjbFfI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D2C1 uniprotkb:X5D2C1 intact:EBI-21246980 intact:EBI-21246980 psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252667|imex:IM-24135-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rigid:lnEIsl0dUkTUnrGJ0yTGZJXZ7MA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5D7A4 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21247765 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252659|imex:IM-24135-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rigid:V8orN2LXwlyfrYc+CTVVM8FhgSc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D7A4 intact:EBI-21247765 intact:EBI-21247765 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252651|imex:IM-24135-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rigid:0Ds3WWUYAa/8yrq97MFphJMWIts false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:P01185 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-6858021|ensembl:ENSP00000369647|uniprotkb:A0AV35|uniprotkb:O14935 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:neu2_human(display_long)|uniprotkb:AVP(gene name)|psi-mi:AVP(display_short)|uniprotkb:ARVP(gene name synonym)|uniprotkb:VP(gene name synonym)|uniprotkb:AVP-NPII(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252643|imex:IM-24135-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) refseq:XP_011527569.1|ensembl:ENSG00000101200(gene)|ensembl:ENST00000380293(transcript)|go:"GO:0002125"(maternal aggressive behavior)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005184"(neuropeptide hormone activity)|go:"GO:0005185"(neurohypophyseal hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006833"(water transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007621"(negative regulation of female receptivity)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031894"(V1A vasopressin receptor binding)|go:"GO:0031895"(V1B vasopressin receptor binding)|go:"GO:0032849"(positive regulation of cellular pH reduction)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033574"(response to testosterone)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051970"(negative regulation of transmission of nerve impulse)|go:"GO:0035813"(regulation of renal sodium excretion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0042310"(vasoconstriction)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR000981(Neurohypophysial hormone)|interpro:IPR022423|interpro:IPR036387|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042711"(maternal behavior)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|rcsb pdb:7KH0|reactome:R-HSA-1368108|reactome:R-HSA-388479|go:"GO:0043084"(penile erection)|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-432040|reactome:R-HSA-5619099|reactome:R-HSA-879518|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9036092|reactome:R-HSA-9660821|refseq:NP_000481.2|entrezgene/locuslink:551(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:gJEuKmkzkofslMInl8lIcRtZlXE9606 rigid:WXtKKKHwKLJNo0IOLNWBsYgFnBM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5DP31 intact:EBI-21247765 intact:EBI-21247516 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252635|imex:IM-24135-1331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:GBmslExw+FajwpXgVer1Pc/mexw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99743 uniprotkb:A0A087WVE9 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252627|imex:IM-24135-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:6sHs4yJVuY98+3XYzHKjI7+V1U8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363 uniprotkb:A0A087WVE9 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252619|imex:IM-24135-761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:dsL75hOVTHJEi2WK7hqhwnRPXjM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:A0A087WVE9 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252611|imex:IM-24135-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:SU1lFVRrkQAASEwbBTNWeDkmHd0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D2C1 uniprotkb:X5D778 intact:EBI-21246980 intact:EBI-17183751|ensembl:ENSP00000496476 psi-mi:x5d2c1_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d778_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252603|imex:IM-24135-1165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) ensembl:ENSG00000167522(gene)|ensembl:ENST00000644285(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042636|entrezgene/locuslink:29123(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:VZDJfE8jUvjm2TGrFvHr8wz340Y9606 rogid:xgi2c9vqau9SVMtbK3deZPfKF3M9606 rigid:AMok8VQV7tr9F7jRzEMn/+3UdZ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NWB1-5 uniprotkb:Q9NWB1-5 intact:EBI-12123390|ensembl:ENSP00000347855 intact:EBI-12123390|ensembl:ENSP00000347855 psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252595|imex:IM-24135-1329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rigid:Er1V5Lr15WMOMxk4y8zbQoECQ7Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17735 uniprotkb:Q05086-3 intact:EBI-12046643|ensembl:ENSP00000348234|uniprotkb:B2R8I1|uniprotkb:D3DWS2 intact:EBI-11026619|ensembl:ENSP00000490258|ensembl:ENSP00000497572 psi-mi:atty_human(display_long)|uniprotkb:TAT(gene name)|psi-mi:TAT(display_short)|uniprotkb:"L-tyrosine:2-oxoglutarate aminotransferase"(gene name synonym) psi-mi:q05086-3(display_long)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252587|imex:IM-24135-1163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198650(gene)|ensembl:ENST00000355962(transcript)|go:"GO:0004838"("L-tyrosine:2-oxoglutarate aminotransferase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046689"(response to mercury ion)|go:"GO:0051384"(response to glucocorticoid)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR005957(Tyrosine aminotransferase)|interpro:IPR005958(Tyrosine/nicotianamine aminotransferase)|interpro:IPR011715(Tyrosine aminotransferase ubiquitination region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:3DYD|reactome:R-HSA-8963684|refseq:NP_000344.1|entrezgene/locuslink:6898(identity) ensembl:ENSG00000114062(gene)|ensembl:ENST00000637886(transcript)|ensembl:ENST00000648336(transcript)|intact:EBI-954357(isoform-parent)|uniprotkb:Q05086-3(isoform-parent)|entrezgene/locuslink:7337(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:cMSTRkOWhlamCV2EKVloh+M/QIk9606 rogid:joMSLIl290tAZwoEGpYGfprWf589606 rigid:5/npwBWy4/XQPHszAXvqrgbzMxc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6IE81-3 uniprotkb:Q05086-3 intact:EBI-12120084|ensembl:ENSP00000404211|ensembl:ENSP00000423737 intact:EBI-11026619|ensembl:ENSP00000490258|ensembl:ENSP00000497572 psi-mi:q6ie81-3(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym)|uniprotkb:JADE1S(isoform synonym) psi-mi:q05086-3(display_long)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252579|imex:IM-24135-1327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IE81-3(isoform-parent)|intact:EBI-954672(isoform-parent)|ensembl:ENSG00000077684(gene)|ensembl:ENST00000413543(transcript)|ensembl:ENST00000511647(transcript)|entrezgene/locuslink:79960(identity) ensembl:ENSG00000114062(gene)|ensembl:ENST00000637886(transcript)|ensembl:ENST00000648336(transcript)|intact:EBI-954357(isoform-parent)|uniprotkb:Q05086-3(isoform-parent)|entrezgene/locuslink:7337(identity) - - - figure legend:Table S3 and Table S4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:H1x2X0aF/gtJu0ZJIql4/DsgYvU9606 rogid:joMSLIl290tAZwoEGpYGfprWf589606 rigid:8QKooNgtpDh74lvqZDceJaz2Al8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48775 uniprotkb:P48775 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053 psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253089|imex:IM-24135-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rogid:S+cyc710I52nIFQWgKhXFul9QZw9606 rigid:AshC+Zvuy75AfbJKJJZ6JFNIjYY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P1A6-3 uniprotkb:X5DP20 intact:EBI-12019838 intact:EBI-21248551 psi-mi:q9p1a6-3(display_long)|uniprotkb:C8orf68(gene name synonym)|uniprotkb:ERICH1-AS1(gene name synonym)|uniprotkb:DLGAP2(gene name)|psi-mi:DLGAP2(display_short)|uniprotkb:DAP2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252783|imex:IM-24135-1169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1753397(isoform-parent)|uniprotkb:Q9P1A6-3(isoform-parent)|entrezgene/locuslink:9228(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:kh1ebyV49QdbaEIxzVEw59bO66A9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:RefGUDvtUF2MkbTS3/BUSF1mPzI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16623 uniprotkb:Q16623 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 intact:EBI-712466|uniprotkb:Q7Z5K3|ensembl:ENSP00000222812|uniprotkb:O15447|uniprotkb:O15448|uniprotkb:Q12936|uniprotkb:Q9BPZ6|uniprotkb:Q75MD9 psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:stx1a_human(display_long)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short)|uniprotkb:STX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253073|imex:IM-24135-1177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:Q16623|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250971|reactome:R-HSA-5682910|reactome:R-HSA-6794361|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|go:"GO:0048278"(vesicle docking)|ensembl:ENSG00000106089(gene)|ensembl:ENST00000222812(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|refseq:NP_001159375.1|refseq:NP_004594.1|dip:DIP-390N|entrezgene/locuslink:6804(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rogid:2OJ1A7RC63MTlOJmpv/jPx4IvGE9606 rigid:czSHeXHxTXkhaktEx381T06k/IE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13363-2 uniprotkb:P63162 intact:EBI-10171858|ensembl:ENSP00000372411 intact:EBI-712493|ensembl:ENSP00000463458|ensembl:ENSP00000494831|ensembl:ENSP00000495345|ensembl:ENSP00000306223|ensembl:ENSP00000375105|ensembl:ENSP00000382969|ensembl:ENSP00000382972|uniprotkb:P14648|uniprotkb:P17135|uniprotkb:Q0D2Q5|uniprotkb:B3KVR1 psi-mi:q13363-2(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:rsmn_human(display_long)|uniprotkb:Tissue-specific-splicing protein(gene name synonym)|uniprotkb:SNRPN(gene name)|psi-mi:SNRPN(display_short)|uniprotkb:HCERN3(gene name synonym)|uniprotkb:SMN(gene name synonym)|uniprotkb:Sm protein N(gene name synonym)|uniprotkb:Sm protein D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253065|imex:IM-24135-1359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-908846(isoform-parent)|uniprotkb:Q13363-2(isoform-parent)|ensembl:ENSG00000159692(gene)|ensembl:ENST00000382952(transcript)|entrezgene/locuslink:1487(identity) ensembl:ENST00000346403(transcript)|ensembl:ENST00000390687(transcript)|ensembl:ENST00000400097(transcript)|ensembl:ENST00000400100(transcript)|ensembl:ENST00000577565(transcript)|ensembl:ENST00000642807(transcript)|ensembl:ENST00000645002(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|ensembl:ENSG00000128739(gene)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P63162|rcsb pdb:5MF9|reactome:R-HSA-72163|go:"GO:0009725"(response to hormone)|refseq:NP_003088.1|refseq:NP_073716.1|refseq:NP_073717.1|refseq:NP_073718.1|refseq:NP_073719.1|refseq:NP_005669.2|entrezgene/locuslink:6638(identity) - isoform-comment:No experimental confirmation available. - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:p8sgnXWuU5viF+U0C5pGFjorrGs9606 rogid:F839ujOi+/hObAvs2L3Majys3E09606 rigid:j4fjQeclIQZO5GduUm86uw3kqRg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7T5 uniprotkb:P63162 intact:EBI-21246658 intact:EBI-712493|ensembl:ENSP00000463458|ensembl:ENSP00000494831|ensembl:ENSP00000495345|ensembl:ENSP00000306223|ensembl:ENSP00000375105|ensembl:ENSP00000382969|ensembl:ENSP00000382972|uniprotkb:P14648|uniprotkb:P17135|uniprotkb:Q0D2Q5|uniprotkb:B3KVR1 psi-mi:x5d7t5_human(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short) psi-mi:rsmn_human(display_long)|uniprotkb:Tissue-specific-splicing protein(gene name synonym)|uniprotkb:SNRPN(gene name)|psi-mi:SNRPN(display_short)|uniprotkb:HCERN3(gene name synonym)|uniprotkb:SMN(gene name synonym)|uniprotkb:Sm protein N(gene name synonym)|uniprotkb:Sm protein D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253057|imex:IM-24135-1339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:XP_011520849.1|interpro:IPR025670|interpro:IPR034237|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|entrezgene/locuslink:54715(identity) ensembl:ENST00000346403(transcript)|ensembl:ENST00000390687(transcript)|ensembl:ENST00000400097(transcript)|ensembl:ENST00000400100(transcript)|ensembl:ENST00000577565(transcript)|ensembl:ENST00000642807(transcript)|ensembl:ENST00000645002(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|ensembl:ENSG00000128739(gene)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P63162|rcsb pdb:5MF9|reactome:R-HSA-72163|go:"GO:0009725"(response to hormone)|refseq:NP_003088.1|refseq:NP_073716.1|refseq:NP_073717.1|refseq:NP_073718.1|refseq:NP_073719.1|refseq:NP_005669.2|entrezgene/locuslink:6638(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:axYIzehe9w6AaW6IfLVFmflFr8U9606 rogid:F839ujOi+/hObAvs2L3Majys3E09606 rigid:+QeWP+fjNCuyMM8/wgL85DvfEUk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NWB1-5 uniprotkb:P63162 intact:EBI-12123390|ensembl:ENSP00000347855 intact:EBI-712493|ensembl:ENSP00000463458|ensembl:ENSP00000494831|ensembl:ENSP00000495345|ensembl:ENSP00000306223|ensembl:ENSP00000375105|ensembl:ENSP00000382969|ensembl:ENSP00000382972|uniprotkb:P14648|uniprotkb:P17135|uniprotkb:Q0D2Q5|uniprotkb:B3KVR1 psi-mi:q9nwb1-5(display_long)|uniprotkb:RBFOX1(gene name)|psi-mi:RBFOX1(display_short)|uniprotkb:A2BP(gene name synonym)|uniprotkb:A2BP1(gene name synonym)|uniprotkb:Ataxin-2-binding protein 1(gene name synonym)|uniprotkb:FOX1(gene name synonym)|uniprotkb:Fox-1 homolog A(gene name synonym)|uniprotkb:HRNBP1(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 1(gene name synonym)|uniprotkb:Beta(isoform synonym) psi-mi:rsmn_human(display_long)|uniprotkb:Tissue-specific-splicing protein(gene name synonym)|uniprotkb:SNRPN(gene name)|psi-mi:SNRPN(display_short)|uniprotkb:HCERN3(gene name synonym)|uniprotkb:SMN(gene name synonym)|uniprotkb:Sm protein N(gene name synonym)|uniprotkb:Sm protein D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253049|imex:IM-24135-799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-945906(isoform-parent)|uniprotkb:Q9NWB1-5(isoform-parent)|ensembl:ENSG00000078328(gene)|ensembl:ENST00000355637(transcript)|entrezgene/locuslink:54715(identity) ensembl:ENST00000346403(transcript)|ensembl:ENST00000390687(transcript)|ensembl:ENST00000400097(transcript)|ensembl:ENST00000400100(transcript)|ensembl:ENST00000577565(transcript)|ensembl:ENST00000642807(transcript)|ensembl:ENST00000645002(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|ensembl:ENSG00000128739(gene)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN)|mint:P63162|rcsb pdb:5MF9|reactome:R-HSA-72163|go:"GO:0009725"(response to hormone)|refseq:NP_003088.1|refseq:NP_073716.1|refseq:NP_073717.1|refseq:NP_073718.1|refseq:NP_073719.1|refseq:NP_005669.2|entrezgene/locuslink:6638(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:4TwIsgw943J0zwVf3vlqdYnUO4E9606 rogid:F839ujOi+/hObAvs2L3Majys3E09606 rigid:GtenzW5iy9J/OsU8uFV8Qn+XN/M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D7N4 intact:EBI-21247765 intact:EBI-21252118 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7n4_human(display_long)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253041|imex:IM-24135-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|refseq:XP_005246303.1|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR019804|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR036964|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:11069(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:hoCSdc5ri+E93yLeocriDHGGBUo9606 rigid:PW+PDuCY81huDeTV6zOhslyuGP4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:Q8WZA2 intact:EBI-21247765 intact:EBI-948476|ensembl:ENSP00000380271|uniprotkb:O95636|uniprotkb:Q8IXK6|uniprotkb:Q8TAA4|uniprotkb:B2R7R3|uniprotkb:B7Z912|uniprotkb:B7Z283|uniprotkb:B7Z3T6 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:rpgf4_human(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:RAPGEF4(gene name)|psi-mi:RAPGEF4(display_short)|uniprotkb:CGEF2(gene name synonym)|uniprotkb:EPAC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253033|imex:IM-24135-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) refseq:NP_001269828.1|refseq:NP_001269829.1|refseq:NP_001269830.1|ensembl:ENSG00000091428(gene)|ensembl:ENST00000397081(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|refseq:NP_001093867.1|refseq:NP_008954.2|refseq:XP_006712268.1|entrezgene/locuslink:11069(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:cYq6CkJ34txlv5XggTyHhvQvcEw9606 rigid:fs5oyOdSsG+Dnz+WDvzR0REvsf8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:O60260 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253025|imex:IM-24135-797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N|entrezgene/locuslink:5071(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rigid:eQQevmdXqKTM5sdZ7uR808QcnFI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7T2 uniprotkb:X5D985 intact:EBI-21247490 intact:EBI-21251348 psi-mi:x5d7t2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5d985_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253017|imex:IM-24135-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NlqyT5IhG1S2qMN50JrRE0ERns89606 rogid:lLfxsDElLRVPopOfvUCTV9P2HMk9606 rigid:+ds8c+wPlBJ3hn37WCPQSWaLQ5A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DP31 uniprotkb:X5D985 intact:EBI-21247516 intact:EBI-21251348 psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5d985_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253009|imex:IM-24135-1337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rogid:lLfxsDElLRVPopOfvUCTV9P2HMk9606 rigid:ru7r8bibnZ1y+GCoLTCTLIJMVAM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5D985 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251348 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5d985_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253001|imex:IM-24135-779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:lLfxsDElLRVPopOfvUCTV9P2HMk9606 rigid:oaHv4KFiBcnlKR3cJUOSaFV9MQ4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7T2 uniprotkb:Q8IXF0-4 intact:EBI-21247490 intact:EBI-21251332 psi-mi:x5d7t2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf04(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252993|imex:IM-24135-777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-4(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NlqyT5IhG1S2qMN50JrRE0ERns89606 rogid:YUGSAXzGTadX+uAOn9M1cRETk849606 rigid:qbTKPwwxqQN72sbFbGY8y2Zm8Sk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:Q8IXF0-4 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251332 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf04(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252985|imex:IM-24135-1175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-4(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:YUGSAXzGTadX+uAOn9M1cRETk849606 rigid:4sTJxthwB3s8QHcxj0StfqtM1Ns false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7T2 uniprotkb:Q8IXF0-2 intact:EBI-21247490 intact:EBI-21251316 psi-mi:x5d7t2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf02(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252977|imex:IM-24135-775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-2(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NlqyT5IhG1S2qMN50JrRE0ERns89606 rogid:EmOyLhrkc5xc32oixYjUy9hg1hU9606 rigid:VponzfyU2wnKbUDspEwUzuW9PGo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DP31 uniprotkb:Q8IXF0-2 intact:EBI-21247516 intact:EBI-21251316 psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf02(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252969|imex:IM-24135-1173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-2(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rogid:EmOyLhrkc5xc32oixYjUy9hg1hU9606 rigid:NFkvRQ/Kk/uMHuX0gcnPxSRMut8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:Q8IXF0-2 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251316 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:q8ixf02(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252961|imex:IM-24135-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) uniprotkb:Q8IXF0-2(isoform-parent)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:EmOyLhrkc5xc32oixYjUy9hg1hU9606 rigid:Nn7em56imqLUurk4HZO5MXHQlxs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7T2 uniprotkb:X5DR67 intact:EBI-21247490 intact:EBI-21251295 psi-mi:x5d7t2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5dr67_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252953|imex:IM-24135-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:NlqyT5IhG1S2qMN50JrRE0ERns89606 rogid:c2SYxaC0SWm3dgukY1X9r8U2BwM9606 rigid:jGip7UhtQy+TAYky9snB+ckEzs0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5DR67 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21251295 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5dr67_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252945|imex:IM-24135-1171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:64067(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:c2SYxaC0SWm3dgukY1X9r8U2BwM9606 rigid:sK+vhd98keQ4Ay9jzx2+93poTAI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IXF0 uniprotkb:X5D7T2 intact:EBI-11322367|uniprotkb:Q86US7|uniprotkb:Q86US6|uniprotkb:Q8IXF2|uniprotkb:Q9H323|uniprotkb:Q9BY81|uniprotkb:Q9Y4L8|ensembl:ENSP00000348460 intact:EBI-21247490 psi-mi:npas3_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP6(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:Member of PAS protein 6(gene name synonym)|uniprotkb:PAS domain-containing protein 6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:x5d7t2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252937|imex:IM-24135-999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158221.1|refseq:NP_001159365.1|refseq:NP_071406.1|refseq:NP_775182.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|ensembl:ENSG00000151322(gene)|ensembl:ENST00000356141(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:64067(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fZP+yFdAxC/o3jdOZaOq1+zcTxw9606 rogid:NlqyT5IhG1S2qMN50JrRE0ERns89606 rigid:bQMc6OxzCo2ndOF085p7BOOyvW8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IXF0 uniprotkb:X5DP31 intact:EBI-11322367|uniprotkb:Q86US7|uniprotkb:Q86US6|uniprotkb:Q8IXF2|uniprotkb:Q9H323|uniprotkb:Q9BY81|uniprotkb:Q9Y4L8|ensembl:ENSP00000348460 intact:EBI-21247516 psi-mi:npas3_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP6(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:Member of PAS protein 6(gene name synonym)|uniprotkb:PAS domain-containing protein 6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:x5dp31_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252929|imex:IM-24135-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158221.1|refseq:NP_001159365.1|refseq:NP_071406.1|refseq:NP_775182.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|ensembl:ENSG00000151322(gene)|ensembl:ENST00000356141(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:64067(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR035965|interpro:IPR013767(PAS fold)|interpro:IPR013655(PAS fold-3)|entrezgene/locuslink:9915(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fZP+yFdAxC/o3jdOZaOq1+zcTxw9606 rogid:jiGcK0phuK4k1ltLxEOFvLZPRnk9606 rigid:dz69SY/11rBUxg6q4nkjJdpoRKk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IXF0 uniprotkb:A0A087WVE9 intact:EBI-11322367|uniprotkb:Q86US7|uniprotkb:Q86US6|uniprotkb:Q8IXF2|uniprotkb:Q9H323|uniprotkb:Q9BY81|uniprotkb:Q9Y4L8|ensembl:ENSP00000348460 intact:EBI-12808086|ensembl:ENSP00000479393 psi-mi:npas3_human(display_long)|uniprotkb:NPAS3(gene name)|psi-mi:NPAS3(display_short)|uniprotkb:BHLHE12(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP6(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 12(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:Member of PAS protein 6(gene name synonym)|uniprotkb:PAS domain-containing protein 6(gene name synonym)|uniprotkb:PASD6(gene name synonym) psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252921|imex:IM-24135-773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158221.1|refseq:NP_001159365.1|refseq:NP_071406.1|refseq:NP_775182.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|ensembl:ENSG00000151322(gene)|ensembl:ENST00000356141(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:64067(identity) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:fZP+yFdAxC/o3jdOZaOq1+zcTxw9606 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rigid:q9gyaLYQt/LoSuUf0c3kLD1va6g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:I3L3G9 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21250849|ensembl:ENSP00000460436|uniprotkb:X5DRB5 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:i3l3g9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252913|imex:IM-24135-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) ensembl:ENSG00000072864(gene)|ensembl:ENST00000572756(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:DvhE4MI/6W5VGqCPkFSNOsWlNtI9606 rigid:NHTQYUcQRFR95XAGEgiTZ5iFigs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DRF9 uniprotkb:X5DRF9 intact:EBI-21250811 intact:EBI-21250811 psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:x5drf9_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252905|imex:IM-24135-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033494|entrezgene/locuslink:54820(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rogid:Wr3uwHVpIDcW3k/+G29Sd0mjxMo9606 rigid:WmncmAOu5z0VKqdaj/YDxZLmjUw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5DP35 intact:EBI-21247765 intact:EBI-21249101 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252897|imex:IM-24135-997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:oilXezYeGKC79vcK19l+/HzQCNs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A087WVE9 uniprotkb:X5DP35 intact:EBI-12808086|ensembl:ENSP00000479393 intact:EBI-21249101 psi-mi:a0a087wve9_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252889|imex:IM-24135-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172379(gene)|ensembl:ENST00000622346(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|entrezgene/locuslink:9915(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:/1pj1F2zTtNzOYiXeNJZ0GKeFXU9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:9T4A+ahOpfVgsp0iP4Y8XiS5Edg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-21247090 uniprotkb:X5DP35 - intact:EBI-21249101 psi-mi:ar(display_short)|psi-mi:EBI-21247090(display_long) psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252881|imex:IM-24135-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:367(identity) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wvdZkJPqNLB1OI88kaK8MSi4FoI9606 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rigid:F38YeSey6LVqrtQJTjXv0TTfayc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5D7R7 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21250265 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252873|imex:IM-24135-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:wpRFy6Ysgx0f166baJHFpyBbXMA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRI5-2 uniprotkb:X5D7R7 intact:EBI-11988027|ensembl:ENSP00000355597 intact:EBI-21250265 psi-mi:q9nri5-2(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)|uniprotkb:LV(isoform synonym) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252865|imex:IM-24135-995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-529989(isoform-parent)|ensembl:ENSG00000162946(gene)|ensembl:ENST00000366637(transcript)|uniprotkb:Q9NRI5-2(isoform-parent)|entrezgene/locuslink:27185(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - isoform-comment:Non-canonical donor and acceptor splice sites for the last 2 exons. - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XO2u/5sOZAkkn12A+INm5SA4jUY9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:prFkwOp8XXqGiNa0yv2jVS7K1P0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D7R7 intact:EBI-21247765 intact:EBI-21250265 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d7r7_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252857|imex:IM-24135-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) interpro:IPR039059|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR041134|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|entrezgene/locuslink:9961(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:m7Hi7lyM33x5/zO4Vqd27OZDGmY9606 rigid:4ZpbabKZ0awTWxIhD7cO6EbiXA8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14764 uniprotkb:Q14764 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252849|imex:IM-24135-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|entrezgene/locuslink:9961(identity) ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|entrezgene/locuslink:9961(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rigid:U6wSPotNf2g4sQeZgORK4QHoryY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15409 uniprotkb:P27361 intact:EBI-983612|uniprotkb:A0AUV6|uniprotkb:A4D0U8|uniprotkb:Q6ZND1|uniprotkb:Q75MJ3|uniprotkb:Q8IZE0|uniprotkb:Q8N0W2|uniprotkb:Q8N6B7|uniprotkb:Q8N6B8|uniprotkb:Q8NFQ1|uniprotkb:Q8NFQ2|uniprotkb:Q8NFQ3|uniprotkb:Q8NFQ4|uniprotkb:Q8TD74|ensembl:ENSP00000265436|ensembl:ENSP00000377132|uniprotkb:A6NNW4|uniprotkb:B4DLD9 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:foxp2_human(display_long)|uniprotkb:CAG repeat protein 44(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 10 protein(gene name synonym)|uniprotkb:FOXP2(gene name)|psi-mi:FOXP2(display_short)|uniprotkb:CAGH44(gene name synonym)|uniprotkb:TNRC10(gene name synonym) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252839|imex:IM-24135-1335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128573(gene)|ensembl:ENST00000350908(transcript)|ensembl:ENST00000393494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021757"(caudate nucleus development)|go:"GO:0021758"(putamen development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0098582"(innate vocalization behavior)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:O15409|rcsb pdb:2A07|rcsb pdb:2AS5|go:"GO:0046872"(metal ion binding)|refseq:NP_001166237.1|refseq:NP_001166238.1|refseq:NP_055306.1|refseq:NP_683696.2|refseq:NP_683697.2|refseq:NP_683698.2|dip:DIP-29004N|refseq:XP_016868290.1|entrezgene/locuslink:93986(identity) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|entrezgene/locuslink:5595(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:XRN9auLs2qtK6W3mjHJHAQPbO9s9606 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:pqanBAE0tAAtJF+j8Yr8YmF8p3k false sufficient binding region:93-715 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:X5D2L7 intact:EBI-21247765 intact:EBI-21249998 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:x5d2l7_human(display_long)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252831|imex:IM-24135-993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:1990939"|interpro:IPR027640|interpro:IPR001752(Kinesin, motor region)|interpro:IPR036961|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|entrezgene/locuslink:547(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:eQKNzGcTVN6BRR7Ur9Ba3VkH0Uo9606 rigid:xOQNFMZ/cTSjLe+2N8Z9pLgkcfk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-21247090 uniprotkb:X5D2L7 - intact:EBI-21249998 psi-mi:ar(display_short)|psi-mi:EBI-21247090(display_long) psi-mi:x5d2l7_human(display_long)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252823|imex:IM-24135-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:367(identity) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:1990939"|interpro:IPR027640|interpro:IPR001752(Kinesin, motor region)|interpro:IPR036961|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|entrezgene/locuslink:547(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:wvdZkJPqNLB1OI88kaK8MSi4FoI9606 rogid:eQKNzGcTVN6BRR7Ur9Ba3VkH0Uo9606 rigid:Agn3RfaS0WboF4JJaEAkyxwB6x0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49789 uniprotkb:P49789 intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9 intact:EBI-741760|uniprotkb:Q6IU12|ensembl:ENSP00000417480|ensembl:ENSP00000417557|ensembl:ENSP00000418582|uniprotkb:A2IAS9|uniprotkb:A2IAT0|uniprotkb:A2IAT6|uniprotkb:A8K1A9|uniprotkb:Q45QG9 psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym) psi-mi:fhit_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Fragile histidine triad protein(gene name synonym)|uniprotkb:FHIT(gene name)|psi-mi:FHIT(display_short)|uniprotkb:Adenosine 5'-monophosphoramidase FHIT(gene name synonym)|uniprotkb:Adenylylsulfatase(gene name synonym)|uniprotkb:Adenylylsulfate-ammonia adenylyltransferase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252815|imex:IM-24135-991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N|entrezgene/locuslink:2272(identity) refseq:NP_001159715.1|refseq:NP_002003.1|ensembl:ENSG00000189283(gene)|ensembl:ENST00000468189(transcript)|ensembl:ENST00000476844(transcript)|ensembl:ENST00000492590(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0015964"(diadenosine triphosphate catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|rcsb pdb:1FHI|rcsb pdb:1FIT|rcsb pdb:2FHI|rcsb pdb:2FIT|rcsb pdb:3FIT|rcsb pdb:4FIT|rcsb pdb:5FIT|rcsb pdb:6FIT|refseq:NP_001307828.1|refseq:NP_001307829.1|dip:DIP-29947N|entrezgene/locuslink:2272(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606 rogid:HP0fEbM1naJPi0XrKdkagXZPF0E9606 rigid:kt+NHRqoKFIxUA4cKxWDRI2Axh4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7A4 uniprotkb:Q9P1A6-3 intact:EBI-21247765 intact:EBI-12019838 psi-mi:x5d7a4_human(display_long)|uniprotkb:BZRAP1(gene name)|psi-mi:BZRAP1(display_short) psi-mi:q9p1a6-3(display_long)|uniprotkb:C8orf68(gene name synonym)|uniprotkb:ERICH1-AS1(gene name synonym)|uniprotkb:DLGAP2(gene name)|psi-mi:DLGAP2(display_short)|uniprotkb:DAP2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252807|imex:IM-24135-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040325|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR001452(Src homology-3)|entrezgene/locuslink:9256(identity) intact:EBI-1753397(isoform-parent)|uniprotkb:Q9P1A6-3(isoform-parent)|entrezgene/locuslink:9228(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:ewD3W7q8Jb4NYghSRSCnjcPcxlU9606 rogid:kh1ebyV49QdbaEIxzVEw59bO66A9606 rigid:5dGvuEhqdlNV6a7yxqjNEPVdo+g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5DP35 uniprotkb:X5DQV8 intact:EBI-21249101 intact:EBI-21249096 psi-mi:x5dp35_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short) psi-mi:x5dqv8_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252799|imex:IM-24135-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0030154"(cell differentiation)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:0000776"(kinetochore)|refseq:XP_016878840.1|refseq:XP_016878841.1|interpro:IPR033494|interpro:IPR006964(NUDE protein, C-terminal)|entrezgene/locuslink:54820(identity) interpro:IPR026081|entrezgene/locuslink:27185(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:1BCuK7heWuZIlHPMZznkTDXix4s9606 rogid:93TNKNHYhusDUfBCskGfHW9ZXOA9606 rigid:jnBF/8erMoylOe9nweXwnErRkbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07687 uniprotkb:X5DP20 intact:EBI-3908234|intact:EBI-28987231|ensembl:ENSP00000234198|uniprotkb:B4DMK4|uniprotkb:B7ZA14 intact:EBI-21248551 psi-mi:dlx2_human(display_long)|uniprotkb:DLX2(gene name)|psi-mi:DLX2(display_short) psi-mi:x5dp20_human(display_long)|uniprotkb:DGCR6(gene name)|psi-mi:DGCR6(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21252791|imex:IM-24135-771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004396.1|ensembl:ENSP00000234198|ensembl:ENST00000466293|ensembl:ENSP00000446904|ensembl:ENSG00000115844(gene)|ensembl:ENST00000234198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:1746(identity) interpro:IPR010849(DiGeorge syndrome critical 6)|entrezgene/locuslink:8214(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:q2XVmJGOg+QrKEqqAYvC5LqS4ag9606 rogid:khU0g/ReLWjeI9TxpPx2j4hVEig9606 rigid:lSJVcgGO+Ge+zIKK6+m2DWu0h/o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:X5D7S1 uniprotkb:X5D7S1 intact:EBI-21252312 intact:EBI-21252312 psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:x5d7s1_human(display_long)|uniprotkb:STX1A(gene name)|psi-mi:STX1A(display_short) psi-mi:"MI:0397"(two hybrid array) Corominas et al. (2013) imex:IM-24135|pubmed:24722188|doi:10.1038/ncomms4650 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21253081|imex:IM-24135-1179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR000727(Target SNARE coiled-coil region)|entrezgene/locuslink:6804(identity) - - - figure legend:Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/04/29 2019/03/18 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rogid:lCnjmsoSNbVGF8X9h9TvvmxQi4Q9606 rigid:upuiYsW2HKUQjHUBv6fxKOXtUSI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)