#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P60520 uniprotkb:Q8IZQ1 intact:EBI-720116|uniprotkb:O08765|uniprotkb:Q9DCP8|uniprotkb:Q9UQF7|intact:EBI-3239397|ensembl:ENSP00000037243|intact:EBI-2973440|uniprotkb:Q6FG91 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:gbrl2_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 2"(gene name synonym)|uniprotkb:Golgi-associated ATPase enhancer of 16 kDa(gene name synonym)|uniprotkb:General protein transport factor p16(gene name synonym)|uniprotkb:Ganglioside expression factor 2(gene name synonym)|uniprotkb:MAP1 light chain 3-related protein(gene name synonym)|uniprotkb:GABARAPL2(gene name)|psi-mi:GABARAPL2(display_short)|uniprotkb:FLC3A(gene name synonym)|uniprotkb:GEF2(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10106953|imex:IM-23810-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009216.1|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0051117"(ATPase binding)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:4CO7|rcsb pdb:6H8C|rcsb pdb:7LK3|reactome:R-HSA-1632852|reactome:R-HSA-8854214|ensembl:ENSG00000034713(gene)|ensembl:ENST00000037243(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|dip:DIP-35051N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2015/02/03 2015/02/06 rogid:hABWDldI6+CiLNmy6WDCNQhm54Q9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:C3B90AD8D6B6B2B3|rigid:Enkc+iv2G2NHkzkaWxhdjeD9BRA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10106921|imex:IM-23810-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:C5B59EEE0832FC8A|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false green fluorescent protein tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZQ1 uniprotkb:Q9BXW4 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10106915|imex:IM-23810-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 intact-crc:14D085B82870FE2E|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IZQ1 uniprotkb:Q9H0R8 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-746969|uniprotkb:Q6FIE6|intact:EBI-3240381|uniprotkb:B4E0Y7|ensembl:ENSP00000266458|ensembl:ENSP00000444186 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:gbrl1_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 1"(gene name synonym)|uniprotkb:Glandular epithelial cell protein 1(gene name synonym)|uniprotkb:Early estrogen-regulated protein(gene name synonym)|uniprotkb:GABARAPL1(gene name)|psi-mi:GABARAPL1(display_short)|uniprotkb:GEC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10106947|imex:IM-23810-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_113600.1|refseq:XP_005253401.1|ensembl:ENSG00000139112(gene)|ensembl:ENST00000266458(transcript)|ensembl:ENST00000545887(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016236"(macroautophagy)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0044297"(cell body)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2L8J|rcsb pdb:2R2Q|rcsb pdb:5DPT|rcsb pdb:5LXH|rcsb pdb:5LXI|rcsb pdb:6HOI|rcsb pdb:6HOL|rcsb pdb:6YOO|rcsb pdb:7AA7|rcsb pdb:7AA9|rcsb pdb:7JHX|reactome:R-HSA-1632852|dip:DIP-35597N - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:X3TVNoI2dr936S1k875QCIVQWbo9606 intact-crc:40238478503A9FB3|rigid:lWFZNEsx6OgxrpOyKtjqZg6TmRE false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10106988|imex:IM-23810-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:sf1a sf1b sf1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:D3772D51FCD1963C|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false green fluorescent protein tag:?-? tandem tag:?-?|sufficient binding region:3255-3526|mutation disrupting interaction:3349-3349 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10106976|imex:IM-23810-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:sf1a sf1b sf1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:57F21FAC137840E9|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false green fluorescent protein tag:?-? sufficient binding region:3255-3526|tandem tag:?-?|mutation disrupting interaction:3346-3346 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BXW4 uniprotkb:Q13501 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455 psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10107161|imex:IM-23810-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1 - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/24 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606 intact-crc:8A4CAF6D5D714A01|rigid:DEFbtAM+YyJAoI5zu6ySqDAhouE false green fluorescent protein tag:?-?|mutation increasing interaction:26-26,27-27,57-57 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BXW4 uniprotkb:Q8IZQ1 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10107161|imex:IM-23810-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/24 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:8A4CAF6D5D714A01|rigid:DEFbtAM+YyJAoI5zu6ySqDAhouE false green fluorescent protein tag:?-?|mutation increasing interaction:26-26,27-27,57-57 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BXW4 uniprotkb:Q8IZQ1 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107038|imex:IM-23810-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:D3497D7DC61972A2|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false glutathione s tranferase tag:?-? binding-associated region:2981-3526 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107012|imex:IM-23810-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:92FD31BA7AE36961|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false glutathione s tranferase tag:?-? binding-associated region:2981-3526 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZQ1 uniprotkb:P60520 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-720116|uniprotkb:O08765|uniprotkb:Q9DCP8|uniprotkb:Q9UQF7|intact:EBI-3239397|ensembl:ENSP00000037243|intact:EBI-2973440|uniprotkb:Q6FG91 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:gbrl2_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 2"(gene name synonym)|uniprotkb:Golgi-associated ATPase enhancer of 16 kDa(gene name synonym)|uniprotkb:General protein transport factor p16(gene name synonym)|uniprotkb:Ganglioside expression factor 2(gene name synonym)|uniprotkb:MAP1 light chain 3-related protein(gene name synonym)|uniprotkb:GABARAPL2(gene name)|psi-mi:GABARAPL2(display_short)|uniprotkb:FLC3A(gene name synonym)|uniprotkb:GEF2(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107022|imex:IM-23810-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009216.1|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0051117"(ATPase binding)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:4CO7|rcsb pdb:6H8C|rcsb pdb:7LK3|reactome:R-HSA-1632852|reactome:R-HSA-8854214|ensembl:ENSG00000034713(gene)|ensembl:ENST00000037243(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|dip:DIP-35051N - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:hABWDldI6+CiLNmy6WDCNQhm54Q9606 intact-crc:3C229F9DC1030675|rigid:Enkc+iv2G2NHkzkaWxhdjeD9BRA false binding-associated region:2981-3526 glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H0R8 uniprotkb:Q8IZQ1 intact:EBI-746969|uniprotkb:Q6FIE6|intact:EBI-3240381|uniprotkb:B4E0Y7|ensembl:ENSP00000266458|ensembl:ENSP00000444186 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:gbrl1_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 1"(gene name synonym)|uniprotkb:Glandular epithelial cell protein 1(gene name synonym)|uniprotkb:Early estrogen-regulated protein(gene name synonym)|uniprotkb:GABARAPL1(gene name)|psi-mi:GABARAPL1(display_short)|uniprotkb:GEC1(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107030|imex:IM-23810-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113600.1|refseq:XP_005253401.1|ensembl:ENSG00000139112(gene)|ensembl:ENST00000266458(transcript)|ensembl:ENST00000545887(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016236"(macroautophagy)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0044297"(cell body)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2L8J|rcsb pdb:2R2Q|rcsb pdb:5DPT|rcsb pdb:5LXH|rcsb pdb:5LXI|rcsb pdb:6HOI|rcsb pdb:6HOL|rcsb pdb:6YOO|rcsb pdb:7AA7|rcsb pdb:7AA9|rcsb pdb:7JHX|reactome:R-HSA-1632852|dip:DIP-35597N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:X3TVNoI2dr936S1k875QCIVQWbo9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:90DA2F85F18D4586|rigid:lWFZNEsx6OgxrpOyKtjqZg6TmRE false glutathione s tranferase tag:?-? binding-associated region:2981-3526 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZQ1 uniprotkb:Q6IAW1 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-10106927 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107448|imex:IM-23810-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) - - - figure legend:f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:7FAA02D3E103AFC6|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false mutation disrupting interaction:3346-3346|maltose binding protein tag:?-?|binding-associated region:3255-3526 glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13501 uniprotkb:Q9GZQ8 intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym) psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107390|imex:IM-23810-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1 ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N - - - figure legend:f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 intact-crc:CDD1CEA00E85C661|rigid:0WM0WoadFwZT1JPf2oBEOFDn3VM false mutation disrupting interaction:340-340|binding-associated region:168-391|maltose binding protein tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107372|imex:IM-23810-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:3A8B0D0A05396EAE|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false mutation disrupting interaction:24-24,25-25,54-54|glutathione s tranferase tag:?-? mutation disrupting interaction:3346-3346|binding-associated region:3255-3526|maltose binding protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107124|imex:IM-23810-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:BD01229C30CA3893|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false - mutation disrupting interaction:3346-3346|maltose binding protein tag:?-?|binding-associated region:3255-3526 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107295|imex:IM-23810-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f3e f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:4D4EED49C6C9DD0A|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false glutathione s tranferase tag:?-?|mutation decreasing interaction:24-24,25-25,54-54 binding-associated region:3255-3526|maltose binding protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IZQ1 uniprotkb:Q9GZQ8 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107464|imex:IM-23810-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N - - - figure legend:f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 intact-crc:3EA4AD8D87B1EDE6|rigid:Nskptsmp9wVsadmy3Gr5dNfoXwc false binding-associated region:3255-3526|maltose binding protein tag:?-?|mutation disrupting interaction:3346-3346 mutation increasing interaction:26-26,27-27,57-57|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13501 uniprotkb:Q6IAW1 intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455 intact:EBI-10106927 psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107422|imex:IM-23810-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1 refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) - - - figure legend:f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:D9BB2390B42A7896|rigid:Ck2Tw8PA9YfvSNE4q7J8dKtPh5I false binding-associated region:168-391|mutation disrupting interaction:340-340|maltose binding protein tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZQ1 uniprotkb:Q9BXW4 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10684034|imex:IM-23810-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/24 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 intact-crc:6F6BF640E50495FD|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false binding-associated region:2981-3526|green fluorescent protein tag:?-?|mutation decreasing interaction:3347-3347 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9BXW4 uniprotkb:Q8IZQ1 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10684046|imex:IM-23810-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/24 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:8AED9DA95565ADD8|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false glutathione s tranferase tag:?-? mutation disrupting interaction:3348-3348|binding-associated region:2981-3526|green fluorescent protein tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9BXW4 uniprotkb:Q9BXW4 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10684046|imex:IM-23810-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/24 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 intact-crc:8AED9DA95565ADD8|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false glutathione s tranferase tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9BXW4 uniprotkb:Q8IZQ1 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10684061|imex:IM-23810-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/24 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:F7882B34F6404961|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false glutathione s tranferase tag:?-? green fluorescent protein tag:?-?|mutation decreasing interaction:3349-3349|binding-associated region:2981-3526 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8IZQ1 uniprotkb:Q6IAW1 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-10106927 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107112|imex:IM-23810-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:91F842189DABD905|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false mutation decreasing interaction:3349-3349|green fluorescent protein tag:?-?|binding-associated region:2981-3526 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8IZQ1 uniprotkb:Q6IAW1 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-10106927 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107100|imex:IM-23810-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:AB50EB860568F7D8|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false mutation decreasing interaction:3348-3348|green fluorescent protein tag:?-?|binding-associated region:2981-3526 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107088|imex:IM-23810-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:1BE9ABA3E015E461|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false glutathione s tranferase tag:?-? mutation decreasing interaction:3347-3347|green fluorescent protein tag:?-?|binding-associated region:2981-3526 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107000|imex:IM-23810-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/24 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:155001B036E7186A|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false glutathione s tranferase tag:?-? green fluorescent protein tag:?-?|binding-associated region:3313-3363 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8IZQ1 uniprotkb:Q6IAW1 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-10106927 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107076|imex:IM-23810-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:9B37C28A0EF2320A|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false mutation disrupting interaction:3346-3346|green fluorescent protein tag:?-?|binding-associated region:2981-3526 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8IZQ1 uniprotkb:Q6IAW1 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-10106927 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0096"(pull down) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107496|imex:IM-23810-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) - - - figure legend:f3g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:1BEEDA13E015E461|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false green fluorescent protein tag:?-?|binding-associated region:2981-3526|mutation decreasing interaction:3343-3343,3344-3344,3351-3351 glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8IZQ1 uniprotkb:P60520 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-720116|uniprotkb:O08765|uniprotkb:Q9DCP8|uniprotkb:Q9UQF7|intact:EBI-3239397|ensembl:ENSP00000037243|intact:EBI-2973440|uniprotkb:Q6FG91 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:gbrl2_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 2"(gene name synonym)|uniprotkb:Golgi-associated ATPase enhancer of 16 kDa(gene name synonym)|uniprotkb:General protein transport factor p16(gene name synonym)|uniprotkb:Ganglioside expression factor 2(gene name synonym)|uniprotkb:MAP1 light chain 3-related protein(gene name synonym)|uniprotkb:GABARAPL2(gene name)|psi-mi:GABARAPL2(display_short)|uniprotkb:FLC3A(gene name synonym)|uniprotkb:GEF2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107069|imex:IM-23810-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_009216.1|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0051117"(ATPase binding)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:4CO7|rcsb pdb:6H8C|rcsb pdb:7LK3|reactome:R-HSA-1632852|reactome:R-HSA-8854214|ensembl:ENSG00000034713(gene)|ensembl:ENST00000037243(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|dip:DIP-35051N - - - figure legend:sf1d f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:871.0x10^-9(molar) 2015/02/03 2015/02/24 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:hABWDldI6+CiLNmy6WDCNQhm54Q9606 intact-crc:30FFB550D1C2EA29|rigid:Enkc+iv2G2NHkzkaWxhdjeD9BRA false binding-associated region:3341-3354 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IZQ1 uniprotkb:Q9BXW4 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-2603996|uniprotkb:A0PJY8|uniprotkb:A2RUP0|intact:EBI-2948714|ensembl:ENSP00000349785 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:mlp3c_human(display_long)|uniprotkb:MAP1LC3C(gene name)|psi-mi:MAP1LC3C(display_short)|uniprotkb:Microtubule-associated protein 1 light chain 3 gamma(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 C(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 C(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 C(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107055|imex:IM-23810-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N refseq:NP_001004343.1|ensembl:ENSG00000197769(gene)|ensembl:ENST00000357246(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035973"(aggrephagy)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR027731|interpro:IPR029071|rcsb pdb:2NCN|rcsb pdb:3VVW|rcsb pdb:3WAM|rcsb pdb:3WAP|rcsb pdb:5DPW|reactome:R-HSA-1632852|refseq:XP_005273196.1|dip:DIP-57020N - - - figure legend:sf1d f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:20.0x10^-6(molar) 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:vGCrQX01yia9auqJN3Gy88W+ffU9606 intact-crc:81438D6104E8802F|rigid:+hXkybIhjjGuG9ed0nAAjd546Zk false binding-associated region:3341-3354 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0R8 uniprotkb:Q8IZQ1 intact:EBI-746969|uniprotkb:Q6FIE6|intact:EBI-3240381|uniprotkb:B4E0Y7|ensembl:ENSP00000266458|ensembl:ENSP00000444186 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:gbrl1_human(display_long)|uniprotkb:"GABA(A) receptor-associated protein-like 1"(gene name synonym)|uniprotkb:Glandular epithelial cell protein 1(gene name synonym)|uniprotkb:Early estrogen-regulated protein(gene name synonym)|uniprotkb:GABARAPL1(gene name)|psi-mi:GABARAPL1(display_short)|uniprotkb:GEC1(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107062|imex:IM-23810-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113600.1|refseq:XP_005253401.1|ensembl:ENSG00000139112(gene)|ensembl:ENST00000266458(transcript)|ensembl:ENST00000545887(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016236"(macroautophagy)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0044297"(cell body)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2L8J|rcsb pdb:2R2Q|rcsb pdb:5DPT|rcsb pdb:5LXH|rcsb pdb:5LXI|rcsb pdb:6HOI|rcsb pdb:6HOL|rcsb pdb:6YOO|rcsb pdb:7AA7|rcsb pdb:7AA9|rcsb pdb:7JHX|reactome:R-HSA-1632852|dip:DIP-35597N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:sf1d f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:387.0x10^-9(molar) 2015/02/03 2015/02/06 rogid:X3TVNoI2dr936S1k875QCIVQWbo9606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:7497C0CDBCC8BB58|rigid:lWFZNEsx6OgxrpOyKtjqZg6TmRE false - binding-associated region:3341-3354 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107046|imex:IM-23810-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N - - - figure legend:sf1d f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:327.0x10^-9(molar) 2015/02/03 2015/02/24 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:C07070B5DB47B6B5|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false - binding-associated region:3341-3354 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10107143|imex:IM-23810-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N rcsb pdb:3WIM - - figure legend:f3a sf2a sf2b st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:0923AB7D496B726B|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false - binding-associated region:3341-3354 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZQ8 uniprotkb:Q6IAW1 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 intact:EBI-10106927 psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107574|imex:IM-23810-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) go:"GO:0005737"(cytoplasm) - - figure legend:sf5b|comment:"while overexpressed ALFY2285–3526 did not colocalize with wild-type GFP- LC3B, colocalization was observed upon the induction of excess GABARAP (Supplementary Fig S5B) or expression of the GFP-LC3B (Q26K/H27Y/H57D) mutant (Supplementary Fig S5B), indicating that the structural determinants identified as being important for GABARAP-ALFY binding specificity also determine colocalization between these proteins."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/06 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 intact-crc:59145A3F63EB21C3|rigid:gXPj+o9GtKkkTPqQpsPowHrOxto false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9GZQ8 uniprotkb:Q8IZQ1 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107574|imex:IM-23810-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N go:"GO:0005737"(cytoplasm) - - figure legend:sf5b|comment:"while overexpressed ALFY2285–3526 did not colocalize with wild-type GFP- LC3B, colocalization was observed upon the induction of excess GABARAP (Supplementary Fig S5B) or expression of the GFP-LC3B (Q26K/H27Y/H57D) mutant (Supplementary Fig S5B), indicating that the structural determinants identified as being important for GABARAP-ALFY binding specificity also determine colocalization between these proteins."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/06 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:59145A3F63EB21C3|rigid:gXPj+o9GtKkkTPqQpsPowHrOxto false - mcherry fluorescent protein tag:?-?|binding-associated region:2285-3526 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q8IZQ1 uniprotkb:Q9GZQ8 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107587|imex:IM-23810-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N go:"GO:0005737"(cytoplasm) - - figure legend:sf5b|comment:"while overexpressed ALFY2285–3526 did not colocalize with wild-type GFP- LC3B, colocalization was observed upon the induction of excess GABARAP (Supplementary Fig S5B) or expression of the GFP-LC3B (Q26K/H27Y/H57D) mutant (Supplementary Fig S5B), indicating that the structural determinants identified as being important for GABARAP-ALFY binding specificity also determine colocalization between these proteins."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/06 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 intact-crc:925A589EDCD5E768|rigid:Nskptsmp9wVsadmy3Gr5dNfoXwc false binding-associated region:2285-3526|mcherry fluorescent protein tag:?-? green fluorescent protein tag:?-?|mutation increasing interaction:26-26,27-27,57-57 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9GZQ8 uniprotkb:Q8IZQ1 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107524|imex:IM-23810-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N go:"GO:0005737"(cytoplasm) - - figure legend:sf3|comment:"We here show that endogenous LC3B (Supplementary Fig S3), as well as stably expressed GFP-GABARAP (Fig 4A), colocalized with endoge- nous ALFY in stress-induced cytoplasmic structures."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/06 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:8BE7E7195D79217F|rigid:Nskptsmp9wVsadmy3Gr5dNfoXwc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q6IAW1 uniprotkb:Q8IZQ1 intact:EBI-10106927 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:q6iaw1_human(display_long)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:hCG_1987397(orf name) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107517|imex:IM-23810-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009209.1|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N go:"GO:0005737"(cytoplasm) - - figure legend:f4a|comment:"We here show that endogenous LC3B (Supplementary Fig S3), as well as stably expressed GFP-GABARAP (Fig 4A), colocalized with endoge- nous ALFY in stress-induced cytoplasmic structures."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/03 2015/02/06 rogid:PRC57VUrKgXozj1jnvgz7MQERK09606 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:0B7AB82E8DFA4939|rigid:9n81vDdQFrdW/VBXuESHC+1mb0Y false green fluorescent protein tag:?-? - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9DCD6 uniprotkb:Q8IZQ1 intact:EBI-10107623|uniprotkb:B1AR49|uniprotkb:Q9QUI7|ensembl:ENSMUSP00000018711 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:gbrap_mouse(display_long)|uniprotkb:Gabarap(gene name)|psi-mi:Gabarap(display_short)|uniprotkb:"GABA(A) receptor-associated protein"(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107615|imex:IM-23810-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062723.1|ensembl:ENSMUSG00000018567(gene)|ensembl:ENSMUST00000018711(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:5YIR|rcsb pdb:6A9X|reactome:R-MMU-1632852|reactome:R-MMU-8854214 refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N go:"GO:0005737"(cytoplasm) - - figure legend:sf4|comment:"We here show that endogenous LC3B (Supplementary Fig S3), as well as stably expressed GFP-GABARAP (Fig 4A), colocalized with endoge- nous ALFY in stress-induced cytoplasmic structures. Interestingly, full-length wild-type GFP-ALFY, but not the LIR mutant, was recruited to GABARAP and LC3B-positive structures when expressed in ALFY-deficient MEFs (Fig 4B and Supplementary Fig S4)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2015/02/03 2015/02/24 rogid:PRC57VUrKgXozj1jnvgz7MQERK010090 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:5DC6BA5960C30970|rigid:snJEnnMfjJLc6vRqL0vqpkzgvZQ false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9CQV6 uniprotkb:Q8IZQ1 intact:EBI-7942066|uniprotkb:Q3U9W5|intact:UNK-5540201|uniprotkb:Q9D1R0|ensembl:ENSMUSP00000034270 intact:EBI-1569256|uniprotkb:Q4W5K5|uniprotkb:Q6P0Q5|uniprotkb:Q8N1T2|uniprotkb:Q8NAV6|uniprotkb:Q96BS7|uniprotkb:Q96D33|uniprotkb:Q96N85|uniprotkb:Q9Y2J7|ensembl:ENSP00000295888 psi-mi:mlp3b_mouse(display_long)|uniprotkb:Map1lc3b(gene name)|psi-mi:Map1lc3b(display_short)|uniprotkb:Map1alc3(gene name synonym)|uniprotkb:Map1lc3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:wdfy3_human(display_long)|uniprotkb:Autophagy-linked FYVE protein(gene name synonym)|uniprotkb:WDFY3(gene name)|psi-mi:WDFY3(display_short)|uniprotkb:KIAA0993(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lystad et al. (2014) pubmed:24668264|imex:IM-23810 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-10107663|imex:IM-23810-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080436.1|dip:DIP-61580N|go:"GO:0012505"(endomembrane system)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044754"(autolysosome)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:5WRD|rcsb pdb:5YIQ|rcsb pdb:5YIS|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8854214|reactome:R-MMU-8934903|reactome:R-MMU-9664873|go:"GO:0009267"(cellular response to starvation)|ensembl:ENSMUSG00000031812(gene)|ensembl:ENSMUST00000034270(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding) refseq:NP_055806.2|refseq:XP_011530065.1|refseq:XP_011530067.1|ensembl:ENSG00000163625(gene)|ensembl:ENST00000295888(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016605"(PML body)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035973"(aggrephagy)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|mint:Q8IZQ1|rcsb pdb:3WIM|rcsb pdb:6W9N go:"GO:0005737"(cytoplasm) comment:mint|function:"Probably involved in formation of autophagosomal vacuoles (autophagosomes)" - figure legend:sf4|comment:"We here show that endogenous LC3B (Supplementary Fig S3), as well as stably expressed GFP-GABARAP (Fig 4A), colocalized with endoge- nous ALFY in stress-induced cytoplasmic structures. Interestingly, full-length wild-type GFP-ALFY, but not the LIR mutant, was recruited to GABARAP and LC3B-positive structures when expressed in ALFY-deficient MEFs (Fig 4B and Supplementary Fig S4)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2015/02/03 2015/02/24 rogid:i7XYb/AU0h/HmGBNN0hFhJJ/GEw10090 rogid:yVIfhD/TU9JhrQR8WCChT4Jpi8c9606 intact-crc:DAF671681F35AE32|rigid:gmrP8EXUUxzExVEvGVpoGw8sd7Y false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence)