#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7KN62 uniprotkb:A1ZAB3 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 intact:EBI-3410206|ensemblmetazoa:FBpp0288423 psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:a1zab3_drome(display_long)|uniprotkb:Ptp52F(gene name)|psi-mi:Ptp52F(display_short)|uniprotkb:Dmel\CG18243(gene name synonym)|uniprotkb:PTP52F(gene name synonym)|uniprotkb:ptp52F(gene name synonym)|uniprotkb:CG18243(orf name)|uniprotkb:Dmel_CG18243(orf name)|uniprotkb:CT18044(gene name synonym)|uniprotkb:DPTP52F(gene name synonym)|uniprotkb:Ptp52F-RB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Santhanam et al. (2014) imex:IM-24176|pubmed:24550005 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10823803|imex:IM-24176-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 refseq:NP_611093.2|flybase:FBgn0034085|ensemblmetazoa:FBgn0034085(gene)|ensemblmetazoa:FBtr0289985(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-DME-1433557|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic) - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2015/05/25 2015/05/25 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rogid:3viEy5jc6nKcX+UBWQ+1+i8FhwQ7227 rigid:0kuG0JtZLE3VmYIa6+7tgI6Jy4c false flag tag:?-? ha tag:?-?|trapping mutant:1258-1258,1290-1290 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7KN62 uniprotkb:A1ZAB3 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 intact:EBI-3410206|ensemblmetazoa:FBpp0288423 psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:a1zab3_drome(display_long)|uniprotkb:Ptp52F(gene name)|psi-mi:Ptp52F(display_short)|uniprotkb:Dmel\CG18243(gene name synonym)|uniprotkb:PTP52F(gene name synonym)|uniprotkb:ptp52F(gene name synonym)|uniprotkb:CG18243(orf name)|uniprotkb:Dmel_CG18243(orf name)|uniprotkb:CT18044(gene name synonym)|uniprotkb:DPTP52F(gene name synonym)|uniprotkb:Ptp52F-RB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Santhanam et al. (2014) imex:IM-24176|pubmed:24550005 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10823814|imex:IM-24176-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 refseq:NP_611093.2|flybase:FBgn0034085|ensemblmetazoa:FBgn0034085(gene)|ensemblmetazoa:FBtr0289985(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-DME-1433557|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic) - - - figure legend:f3e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2015/05/25 2015/05/25 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rogid:3viEy5jc6nKcX+UBWQ+1+i8FhwQ7227 rigid:0kuG0JtZLE3VmYIa6+7tgI6Jy4c false - ha tag:?-?|trapping mutant:1258-1258,1290-1290 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7KN62 uniprotkb:A1ZAB3 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 intact:EBI-3410206|ensemblmetazoa:FBpp0288423 psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:a1zab3_drome(display_long)|uniprotkb:Ptp52F(gene name)|psi-mi:Ptp52F(display_short)|uniprotkb:Dmel\CG18243(gene name synonym)|uniprotkb:PTP52F(gene name synonym)|uniprotkb:ptp52F(gene name synonym)|uniprotkb:CG18243(orf name)|uniprotkb:Dmel_CG18243(orf name)|uniprotkb:CT18044(gene name synonym)|uniprotkb:DPTP52F(gene name synonym)|uniprotkb:Ptp52F-RB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Santhanam et al. (2014) imex:IM-24176|pubmed:24550005 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10823841|imex:IM-24176-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 refseq:NP_611093.2|flybase:FBgn0034085|ensemblmetazoa:FBgn0034085(gene)|ensemblmetazoa:FBtr0289985(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-DME-1433557|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic) - - - figure legend:f5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2015/05/25 2015/05/25 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rogid:3viEy5jc6nKcX+UBWQ+1+i8FhwQ7227 rigid:0kuG0JtZLE3VmYIa6+7tgI6Jy4c false flag tag:?-?|mutation disrupting interaction:800-800 ha tag:?-?|trapping mutant:1258-1258,1290-1290 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A1ZAB3 uniprotkb:Q9V9J3 intact:EBI-3410206|ensemblmetazoa:FBpp0288423 intact:EBI-168188|uniprotkb:O18369|uniprotkb:Q0E9P0|uniprotkb:Q26297|uniprotkb:Q94879|ensemblmetazoa:FBpp0307254 psi-mi:a1zab3_drome(display_long)|uniprotkb:Ptp52F(gene name)|psi-mi:Ptp52F(display_short)|uniprotkb:Dmel\CG18243(gene name synonym)|uniprotkb:PTP52F(gene name synonym)|uniprotkb:ptp52F(gene name synonym)|uniprotkb:CG18243(orf name)|uniprotkb:Dmel_CG18243(orf name)|uniprotkb:CT18044(gene name synonym)|uniprotkb:DPTP52F(gene name synonym)|uniprotkb:Ptp52F-RB(gene name synonym) psi-mi:src42_drome(display_long)|uniprotkb:Src42A(gene name)|psi-mi:Src42A(display_short)|uniprotkb:Src41(gene name synonym)|uniprotkb:TK5(gene name synonym)|uniprotkb:Tyrosine-protein kinase Src41(gene name synonym)|uniprotkb:CG44128(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Santhanam et al. (2014) imex:IM-24176|pubmed:24550005 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10823854|imex:IM-24176-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611093.2|flybase:FBgn0034085|ensemblmetazoa:FBgn0034085(gene)|ensemblmetazoa:FBtr0289985(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-DME-1433557|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic) refseq:NP_476849.1|flybase:FBgn0264959|ensemblmetazoa:FBtr0335275(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034332"(adherens junction organization)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045087"(innate immune response)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048749"(compound eye development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|ensemblmetazoa:FBgn0264959(gene)|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-432553|reactome:R-DME-6798695|reactome:R-DME-8948751|dip:DIP-22220N - - - figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2015/05/25 2015/05/25 rogid:3viEy5jc6nKcX+UBWQ+1+i8FhwQ7227 rogid:z9bgafIXCWT+XeThEho+NYJ58Qc7227 rigid:jhBB8R4W/qUUVam5Qeh6K2oDHWs false ha tag:?-?|trapping mutant:1258-1258,1290-1290 myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A1ZAB3 uniprotkb:Q7KN62 intact:EBI-3410206|ensemblmetazoa:FBpp0288423 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 psi-mi:a1zab3_drome(display_long)|uniprotkb:Ptp52F(gene name)|psi-mi:Ptp52F(display_short)|uniprotkb:Dmel\CG18243(gene name synonym)|uniprotkb:PTP52F(gene name synonym)|uniprotkb:ptp52F(gene name synonym)|uniprotkb:CG18243(orf name)|uniprotkb:Dmel_CG18243(orf name)|uniprotkb:CT18044(gene name synonym)|uniprotkb:DPTP52F(gene name synonym)|uniprotkb:Ptp52F-RB(gene name synonym) psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Santhanam et al. (2014) imex:IM-24176|pubmed:24550005 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10823854|imex:IM-24176-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611093.2|flybase:FBgn0034085|ensemblmetazoa:FBgn0034085(gene)|ensemblmetazoa:FBtr0289985(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-DME-1433557|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic) refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 - - - figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2015/05/25 2015/05/25 rogid:3viEy5jc6nKcX+UBWQ+1+i8FhwQ7227 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rigid:jhBB8R4W/qUUVam5Qeh6K2oDHWs false ha tag:?-?|trapping mutant:1258-1258,1290-1290 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7KN62 uniprotkb:A1ZAB3 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 intact:EBI-3410206|ensemblmetazoa:FBpp0288423 psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:a1zab3_drome(display_long)|uniprotkb:Ptp52F(gene name)|psi-mi:Ptp52F(display_short)|uniprotkb:Dmel\CG18243(gene name synonym)|uniprotkb:PTP52F(gene name synonym)|uniprotkb:ptp52F(gene name synonym)|uniprotkb:CG18243(orf name)|uniprotkb:Dmel_CG18243(orf name)|uniprotkb:CT18044(gene name synonym)|uniprotkb:DPTP52F(gene name synonym)|uniprotkb:Ptp52F-RB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Santhanam et al. (2014) imex:IM-24176|pubmed:24550005 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10823832|imex:IM-24176-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 refseq:NP_611093.2|flybase:FBgn0034085|ensemblmetazoa:FBgn0034085(gene)|ensemblmetazoa:FBtr0289985(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|reactome:R-DME-1433557|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic) - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-pupa)|taxid:7227(Drosophila melanogaster pupa) - 2015/05/25 2015/05/25 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rogid:3viEy5jc6nKcX+UBWQ+1+i8FhwQ7227 rigid:0kuG0JtZLE3VmYIa6+7tgI6Jy4c false - ha tag:?-?|trapping mutant:1258-1258 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)