#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9QXG9 uniprotkb:P70371 intact:EBI-8788053|uniprotkb:E9Q126 intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71 psi-mi:tinf2_mouse(display_long)|uniprotkb:Tinf2(gene name)|psi-mi:Tinf2(display_short)|uniprotkb:Tin2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym) psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Frescas et al. (2014) imex:IM-24139|pubmed:24469404 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10814199|imex:IM-24139-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039098|interpro:IPR029400|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0010370"(perinucleolar chromocenter)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0032202"(telomere assembly)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:1904356"(regulation of telomere maintenance via telomere lengthening)|go:"GO:0005654"(nucleoplasm)|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-2559586|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-9670095 ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N - - - figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2015/04/30 2015/04/30 rogid:IA6cSZz0XzqX19fQDXcO/ZR419U10090 rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090 rigid:HGXtFzbBuMiWg4o6JhTT0SaMdVM false tandem tag:?-?|mutation disrupting interaction:247-247 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)