#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H845 uniprotkb:O75306 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:O75489 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:P03923 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-1246099|uniprotkb:Q34774|uniprotkb:Q8HG30|intact:EBI-28985719|ensembl:ENSP00000354665 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:nu6m_human(display_long)|uniprotkb:MT-ND6(gene name)|psi-mi:MT-ND6(display_short)|uniprotkb:MTND6(gene name synonym)|uniprotkb:NADH6(gene name synonym)|uniprotkb:ND6(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:YP_003024037.1|ensembl:ENSP00000354665|ensembl:ENSG00000198695(gene)|ensembl:ENST00000361681(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070469"(respirasome)|interpro:IPR001457(NADH-ubiquinone/plastoquinone oxidoreductase, chain 6)|mint:P03923|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:RuqWsG2c5WKw60frXqUSTzUY1c09606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:P11182 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-359002|uniprotkb:Q5VVL8|uniprotkb:B2R811|intact:EBI-1058407|ensembl:ENSP00000359151 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:odb2_human(display_long)|uniprotkb:DBT(gene name)|psi-mi:DBT(display_short)|uniprotkb:BCATE2(gene name synonym)|uniprotkb:"Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase"(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)|uniprotkb:52 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Branched chain 2-oxo-acid dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:NP_001909.3|ensembl:ENSG00000137992(gene)|ensembl:ENST00000370132(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P11182|rcsb pdb:1K8M|rcsb pdb:1K8O|rcsb pdb:1ZWV|rcsb pdb:2COO|rcsb pdb:3RNM|reactome:R-HSA-389661|reactome:R-HSA-70895|reactome:R-HSA-9013407 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:Q+c6k43BrkvtPPFCOW5pfJltPsU9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q9BU61 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q9NPL8 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q9UG63 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q9UNX3 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q8IUX1 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-2800657|uniprotkb:Q32Q09|uniprotkb:Q9NZ29|uniprotkb:Q96EP3|uniprotkb:Q8WVU3|uniprotkb:A8K535|uniprotkb:A8MSS0|ensembl:ENSP00000351737 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:t126b_human(display_long)|uniprotkb:TMEM126B(gene name)|psi-mi:TMEM126B(display_short)|uniprotkb:Transmembrane protein 126B(gene name synonym)|uniprotkb:HT007(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:XP_011543467.1|refseq:NP_001180467.1|refseq:NP_060950.3|refseq:NP_001243475.1|ensembl:ENSG00000171204(gene)|ensembl:ENST00000358867(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009801(Protein of unknown function DUF1370)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:eQNEaTeYOl8NJlnxhrTi3R6m66I9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q9Y375 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q5T2R2 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-10762867|uniprotkb:Q53F75|uniprotkb:Q6P473|uniprotkb:Q86WQ8|uniprotkb:Q9Y2W5|ensembl:ENSP00000365388 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:dps1_human(display_long)|uniprotkb:All-trans-decaprenyl-diphosphate synthase subunit 1(gene name synonym)|uniprotkb:Decaprenyl pyrophosphate synthase subunit 1(gene name synonym)|uniprotkb:Trans-prenyltransferase 1(gene name synonym)|uniprotkb:PDSS1(gene name)|psi-mi:PDSS1(display_short)|uniprotkb:DPS1(gene name synonym)|uniprotkb:TPRT(gene name synonym)|uniprotkb:Decaprenyl-diphosphate synthase subunit 1(gene name synonym)|uniprotkb:Solanesyl-diphosphate synthase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N refseq:NP_001308907.1|refseq:NP_055132.2|ensembl:ENSG00000148459(gene)|ensembl:ENST00000376215(transcript)|go:"GO:0000010"(trans-hexaprenyltranstransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050347"(trans-octaprenyltranstransferase activity)|go:"GO:0097269"(all-trans-decaprenyl-diphosphate synthase activity)|go:"GO:1990234"(transferase complex)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|reactome:R-HSA-2142789 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:n+m/XGsR1P4kNdGpA8ji8CT+5qs9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H845 uniprotkb:Q9BQ95 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761587|imex:IM-24050-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:Aqca0K6uJGLhfGrMtNY4w5h69hI false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q07973 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-7969593|uniprotkb:Q32ML3|intact:MINT-6773699|uniprotkb:Q15807|uniprotkb:Q5I2W7|ensembl:ENSP00000216862 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:cp24a_human(display_long)|uniprotkb:Cytochrome P450-CC24(gene name synonym)|uniprotkb:CYP24A1(gene name)|psi-mi:CYP24A1(display_short)|uniprotkb:CYP24(gene name synonym)|uniprotkb:Cytochrome P450 24A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_001122387.1|refseq:NP_000773.2|refseq:XP_005260361.1|refseq:XP_016883180.1|refseq:XP_016883181.1|refseq:XP_016883182.1|ensembl:ENSG00000019186(gene)|ensembl:ENST00000216862(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006766"(vitamin metabolic process)|go:"GO:0008403"(25-hydroxycholecalciferol-24-hydroxylase activity)|go:"GO:0010430"(fatty acid omega-oxidation)|go:"GO:0020037"(heme binding)|go:"GO:0030342"(1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity)|go:"GO:0033280"(response to vitamin D)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0042369"(vitamin D catabolic process)|go:"GO:0062180"(25-hydroxycholecalciferol-23-hydroxylase activity)|go:"GO:0062181"(1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070643"(vitamin D 25-hydroxylase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|mint:Q07973|reactome:R-HSA-196791|reactome:R-HSA-211916|reactome:R-HSA-5579010 - - function:"Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product"|comment:mint figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:Ex5pfgTIWHYz/O4jubrUeS/DQk49606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9NX14 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:P28331 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:P03905 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:O75306 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:O75600 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-2959690|ensembl:ENSP00000248924|uniprotkb:Q96CA9|uniprotkb:E2QC23|uniprotkb:Q6ZWF1 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:kbl_human(display_long)|uniprotkb:GCAT(gene name)|psi-mi:GCAT(display_short)|uniprotkb:KBL(gene name synonym)|uniprotkb:Aminoacetone synthase(gene name synonym)|uniprotkb:Glycine acetyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 ensembl:ENSG00000100116(gene)|ensembl:ENST00000248924(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0008890"(glycine C-acetyltransferase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0019518"(L-threonine catabolic process to glycine)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-8849175|refseq:NP_055106.1|refseq:NP_001165161.1|refseq:XP_005261467.1|refseq:XP_016884166.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:JcxSdpqnWgMx3m5s6nO38OjqO+I9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9NSE4 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q5T9A4 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9HCC0 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9BU61 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:P05556 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9Y2R5 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-1046443|ensembl:ENSP00000285298|uniprotkb:Q86X15 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:rt17_human(display_long)|uniprotkb:MRPS17(gene name)|psi-mi:MRPS17(display_short)|uniprotkb:RPMS17(gene name synonym)|uniprotkb:HSPC011(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS17m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 ensembl:ENSG00000239789(gene)|ensembl:ENST00000285298(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR039193|mint:Q9Y2R5|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|reactome:R-HSA-5389840|rcsb pdb:6ZSB|reactome:R-HSA-5419276|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|refseq:NP_057053.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:UDEpLcg5pGMMYvvc72HnPf9169U9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9NPL8 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9BUB7 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-726363|uniprotkb:Q9NWY5|uniprotkb:E9PDY9|ensembl:ENSP00000312599 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:tmm70_human(display_long)|uniprotkb:TMEM70(gene name)|psi-mi:TMEM70(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_001035703.1|refseq:NP_060336.3|ensembl:ENSG00000175606(gene)|ensembl:ENST00000312184(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR009724(Protein of unknown function DUF1301)|mint:Q9BUB7|go:"GO:0005743"(mitochondrial inner membrane) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:6LHWSQP2W1CRBgylWi8Ncc3X/3E9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q8IUX1 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-2800657|uniprotkb:Q32Q09|uniprotkb:Q9NZ29|uniprotkb:Q96EP3|uniprotkb:Q8WVU3|uniprotkb:A8K535|uniprotkb:A8MSS0|ensembl:ENSP00000351737 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:t126b_human(display_long)|uniprotkb:TMEM126B(gene name)|psi-mi:TMEM126B(display_short)|uniprotkb:Transmembrane protein 126B(gene name synonym)|uniprotkb:HT007(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:XP_011543467.1|refseq:NP_001180467.1|refseq:NP_060950.3|refseq:NP_001243475.1|ensembl:ENSG00000171204(gene)|ensembl:ENST00000358867(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009801(Protein of unknown function DUF1370)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:eQNEaTeYOl8NJlnxhrTi3R6m66I9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9H845 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9BQP7 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-739561|uniprotkb:Q96SW3|uniprotkb:B2RDG5|uniprotkb:D3DW29|ensembl:ENSP00000366939 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:mgme1_human(display_long)|uniprotkb:DDK1(gene name synonym)|uniprotkb:MGME1(gene name)|psi-mi:MGME1(display_short)|uniprotkb:C20orf72(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_443097.1|ensembl:ENSG00000125871(gene)|ensembl:ENST00000377710(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0008297"(single-stranded DNA exodeoxyribonuclease activity)|go:"GO:0043504"(mitochondrial DNA repair)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR038726|mint:Q9BQP7|rcsb pdb:5ZYT|rcsb pdb:5ZYU|rcsb pdb:5ZYV|rcsb pdb:5ZYW|refseq:XP_016883616.1|refseq:XP_016883617.1|refseq:NP_001297267.1|refseq:NP_001297268.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:u0259b2csxQpZ6ZYN/Q1HGeKChk9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q96B77 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-9089409|uniprotkb:B2RAY0|uniprotkb:Q9Y4T4|ensembl:ENSP00000331640 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:tm186_human(display_long)|uniprotkb:C16orf51(gene name synonym)|uniprotkb:TMEM186(gene name)|psi-mi:TMEM186(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_056236.2|ensembl:ENSG00000184857(gene)|ensembl:ENST00000333050(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026571|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:x+vajajo/J0W0DVGKWU12wFid3c9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BQ95 uniprotkb:Q9Y375 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761679|imex:IM-24050-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/01 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:DDNUVXw4tWBH3jZ2xT1hs98rA/A false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q6UXV4 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-9641073|uniprotkb:Q3KNU7|uniprotkb:Q5H9D1|ensembl:ENSP00000362268 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:mic27_human(display_long)|uniprotkb:APOOL(gene name)|psi-mi:APOOL(display_short)|uniprotkb:CXorf33(gene name synonym)|uniprotkb:FAM121A(gene name synonym)|uniprotkb:Protein FAM121A(gene name synonym)|uniprotkb:UNQ8193/PRO23204(orf name)|uniprotkb:Apolipoprotein O-like(gene name synonym)|uniprotkb:MIC27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_940852.3|dip:DIP-47309N|ensembl:ENSG00000155008(gene)|ensembl:ENST00000373173(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR019166|interpro:IPR033182|mint:Q6UXV4|reactome:R-HSA-114608|reactome:R-HSA-8949613 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:ylhhtQDkjSpam535KFeGRCsybfE9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O43678 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O00483 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O75251 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q16718 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O00217 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q9NX14 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P03886 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O75489 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O95168 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P47985 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O95182 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O96000 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q86Y39 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P03915 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O75306 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P56181 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P31930 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_003356.2|ensembl:ENSG00000010256(gene)|ensembl:ENST00000203407(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q16795 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P19404 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O95139 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1053340|uniprotkb:Q6IB84|ensembl:ENSP00000369176|uniprotkb:A8K0Y7|uniprotkb:Q5VYT2 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B17 subunit(gene name synonym)|uniprotkb:Complex I-B17(gene name synonym)|uniprotkb:NDUFB6(gene name)|psi-mi:NDUFB6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000165264(gene)|ensembl:ENST00000379847(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR019174|mint:O95139|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_877416.1|refseq:NP_002484.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:topkNBeCU1z26byuWjSujC8PshA9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P49821 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O95169 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P28331 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O43181 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O75380 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-719854|ensembl:ENSP00000274137 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O43676 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-718365|uniprotkb:Q6IB80|ensembl:ENSP00000237889|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000410600|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub3_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NDUFB3(gene name)|psi-mi:NDUFB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002482.1|refseq:XP_011509532.1|refseq:XP_016859675.1|refseq:NP_001244031.1|ensembl:ENSP00000237889|ensembl:ENSP00000410600|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208|ensembl:ENSG00000119013(gene)|ensembl:ENST00000237889(transcript)|ensembl:ENST00000433898(transcript)|ensembl:ENST00000450023(transcript)|ensembl:ENST00000454214(transcript)|ensembl:ENST00000682325(transcript)|ensembl:ENST00000684175(transcript)|ensembl:ENST00000684420(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:APgw3aIZyyqiPCXMFJ9dUYPQhVE9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q9P0J0 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q16891 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q92934 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P56556 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:O43674 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246293|uniprotkb:Q561V6|ensembl:ENSP00000259037 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub5_human(display_long)|uniprotkb:NDUFB5(gene name)|psi-mi:NDUFB5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)|uniprotkb:Complex I-SGDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186886.1|refseq:NP_001186887.1|refseq:NP_002483.1|ensembl:ENSG00000136521(gene)|ensembl:ENST00000259037(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:1UrbNq39EsuKHJ2M7tRd8ZmB6uk9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P17568 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1246238|uniprotkb:Q9UI16|uniprotkb:Q6ICN9|ensembl:ENSP00000215565 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub7_human(display_long)|uniprotkb:NDUFB7(gene name)|psi-mi:NDUFB7(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B18 subunit(gene name synonym)|uniprotkb:Complex I-B18(gene name synonym)|uniprotkb:Cell adhesion protein SQM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004137.2|ensembl:ENSG00000099795(gene)|ensembl:ENST00000215565(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008698(NADH-ubiquinone oxidoreductase B18 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:9ghtJGrnow8MT1PKXEV2aYuzk0w9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P09669 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-715040|uniprotkb:B2R4D7|ensembl:ENSP00000297564|ensembl:ENSP00000428150|ensembl:ENSP00000428702|ensembl:ENSP00000428895|ensembl:ENSP00000428965|ensembl:ENSP00000429410|ensembl:ENSP00000429707|ensembl:ENSP00000429714|ensembl:ENSP00000429755|ensembl:ENSP00000429991 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:cox6c_human(display_long)|uniprotkb:COX6C(gene name)|psi-mi:COX6C(display_short)|uniprotkb:Cytochrome c oxidase polypeptide VIc(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004365.1|refseq:XP_016868509.1|ensembl:ENSG00000164919(gene)|ensembl:ENST00000297564(transcript)|ensembl:ENST00000517682(transcript)|ensembl:ENST00000518171(transcript)|ensembl:ENST00000520271(transcript)|ensembl:ENST00000520468(transcript)|ensembl:ENST00000520517(transcript)|ensembl:ENST00000522934(transcript)|ensembl:ENST00000522940(transcript)|ensembl:ENST00000523016(transcript)|ensembl:ENST00000524245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004204(Cytochrome c oxidase subunit VIc)|interpro:IPR034884|interpro:IPR037169|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0006091"(generation of precursor metabolites and energy) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:Zha4dqasvkWw3ACebJNflgxCVKo9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:Q9Y6M9 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-713654|uniprotkb:Q9UQE8|uniprotkb:B2R8M6|ensembl:ENSP00000276689|ensembl:ENSP00000504235 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:ndub9_human(display_long)|uniprotkb:LYRM3(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B22 subunit(gene name synonym)|uniprotkb:Complex I-B22(gene name synonym)|uniprotkb:LYR motif-containing protein 3(gene name synonym)|uniprotkb:NDUFB9(gene name)|psi-mi:NDUFB9(display_short)|uniprotkb:UQOR22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 rcsb pdb:5XTH|rcsb pdb:5XTD|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000147684(gene)|ensembl:ENST00000276689(transcript)|ensembl:ENST00000677021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR033034|mint:Q9Y6M9|rcsb pdb:5XTC|refseq:NP_001298097.1|refseq:NP_004996.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:sNQcYhIFMHZA5T6MeeiwAeAJ5Gs9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UI09 uniprotkb:P07919 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 intact:EBI-1224427|uniprotkb:Q5TDF6|uniprotkb:Q6LDB8|uniprotkb:Q9BQ91|uniprotkb:D3DQ18|uniprotkb:B2R4V9|ensembl:ENSP00000309565 psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:qcr6_human(display_long)|uniprotkb:UQCRH(gene name)|psi-mi:UQCRH(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex 11 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 11 kDa protein(gene name synonym)|uniprotkb:Mitochondrial hinge protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10761742|imex:IM-24050-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_005995.2|ensembl:ENSG00000173660(gene)|ensembl:ENST00000311672(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR003422(Ubiquinol-cytochrome C reductase hinge)|interpro:IPR023184|interpro:IPR036811|mint:P07919|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rogid:1f1RPTV/dS3CK24n/YSvDPXLm5c9606 rigid:6IH2jOH6eCDiLWqocEVHJVi7b6Q false tandem tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O95168 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q9NX14 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P03886 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O96000 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q16718 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O00217 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O95182 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P49821 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O43678 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q86Y39 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q9UI09 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P03915 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O95169 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O75251 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P03923 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246099|uniprotkb:Q34774|uniprotkb:Q8HG30|intact:EBI-28985719|ensembl:ENSP00000354665 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nu6m_human(display_long)|uniprotkb:MT-ND6(gene name)|psi-mi:MT-ND6(display_short)|uniprotkb:MTND6(gene name synonym)|uniprotkb:NADH6(gene name synonym)|uniprotkb:ND6(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:YP_003024037.1|ensembl:ENSP00000354665|ensembl:ENSG00000198695(gene)|ensembl:ENST00000361681(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070469"(respirasome)|interpro:IPR001457(NADH-ubiquinone/plastoquinone oxidoreductase, chain 6)|mint:P03923|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:RuqWsG2c5WKw60frXqUSTzUY1c09606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q16795 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P19404 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q9P0J0 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O75306 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P28331 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P56181 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q9H845 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q9BU61 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:P17568 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246238|uniprotkb:Q9UI16|uniprotkb:Q6ICN9|ensembl:ENSP00000215565 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndub7_human(display_long)|uniprotkb:NDUFB7(gene name)|psi-mi:NDUFB7(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B18 subunit(gene name synonym)|uniprotkb:Complex I-B18(gene name synonym)|uniprotkb:Cell adhesion protein SQM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_004137.2|ensembl:ENSG00000099795(gene)|ensembl:ENST00000215565(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008698(NADH-ubiquinone oxidoreductase B18 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:9ghtJGrnow8MT1PKXEV2aYuzk0w9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:Q9BQ95 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75489 uniprotkb:O43678 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762687|imex:IM-24050-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - crc64:C058D62779BEF17B - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/30 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:5pVOzb3vobzuS1DVKjSEJ1hsyOc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P03886 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:Q9UI09 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O00217 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O95182 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O75489 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O95168 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P03905 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P49821 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O96000 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:Q86Y39 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P03915 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O75306 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O95169 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O43678 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:O14548 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-743578|uniprotkb:Q9P118|ensembl:ENSP00000234301|ensembl:ENSP00000367938 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:cox7r_human(display_long)|uniprotkb:Cytochrome c oxidase subunit VIIa-related protein(gene name synonym)|uniprotkb:COX7a-related protein(gene name synonym)|uniprotkb:EB1(gene name synonym)|uniprotkb:COX7RP(gene name synonym)|uniprotkb:COX7A2L(gene name)|psi-mi:COX7A2L(display_short)|uniprotkb:COX7AR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004709.2|refseq:NP_001305965.1|refseq:NP_001305969.1|ensembl:ENSG00000115944(gene)|ensembl:ENST00000234301(transcript)|ensembl:ENST00000378669(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR017267(Cytochrome c oxidase subunit VIIa-related, mitochondrial)|interpro:IPR036539|interpro:IPR039297|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:qJHxwSXSwyenuqJmKPhQ3R76aqE9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P19404 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P56181 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:Q9P0J0 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:Q16795 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43181 uniprotkb:P28331 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762717|imex:IM-24050-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:SS/6v3Ctk6nZvZ+Im9H+j7gF36s false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9NX14 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q16718 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O95168 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O75489 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O43678 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P03886 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O00217 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P03923 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246099|uniprotkb:Q34774|uniprotkb:Q8HG30|intact:EBI-28985719|ensembl:ENSP00000354665 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nu6m_human(display_long)|uniprotkb:MT-ND6(gene name)|psi-mi:MT-ND6(display_short)|uniprotkb:MTND6(gene name synonym)|uniprotkb:NADH6(gene name synonym)|uniprotkb:ND6(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024037.1|ensembl:ENSP00000354665|ensembl:ENSG00000198695(gene)|ensembl:ENST00000361681(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070469"(respirasome)|interpro:IPR001457(NADH-ubiquinone/plastoquinone oxidoreductase, chain 6)|mint:P03923|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:RuqWsG2c5WKw60frXqUSTzUY1c09606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O14548 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-743578|uniprotkb:Q9P118|ensembl:ENSP00000234301|ensembl:ENSP00000367938 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:cox7r_human(display_long)|uniprotkb:Cytochrome c oxidase subunit VIIa-related protein(gene name synonym)|uniprotkb:COX7a-related protein(gene name synonym)|uniprotkb:EB1(gene name synonym)|uniprotkb:COX7RP(gene name synonym)|uniprotkb:COX7A2L(gene name)|psi-mi:COX7A2L(display_short)|uniprotkb:COX7AR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004709.2|refseq:NP_001305965.1|refseq:NP_001305969.1|ensembl:ENSG00000115944(gene)|ensembl:ENST00000234301(transcript)|ensembl:ENST00000378669(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR017267(Cytochrome c oxidase subunit VIIa-related, mitochondrial)|interpro:IPR036539|interpro:IPR039297|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:qJHxwSXSwyenuqJmKPhQ3R76aqE9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O75380 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-719854|ensembl:ENSP00000274137 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O75251 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P47985 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O95182 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P03905 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P56556 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P49821 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q86Y39 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O95831 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O43181 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P03915 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P31930 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_003356.2|ensembl:ENSG00000010256(gene)|ensembl:ENST00000203407(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O96000 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P28838 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-2339312|uniprotkb:Q6IAM6|uniprotkb:Q6P0L6|uniprotkb:Q9UQE3|uniprotkb:B3KMQ3|ensembl:ENSP00000226299|ensembl:ENSP00000481000 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ampl_human(display_long)|uniprotkb:LAP3(gene name)|psi-mi:LAP3(display_short)|uniprotkb:LAPEP(gene name synonym)|uniprotkb:PEPS(gene name synonym)|uniprotkb:Leucyl aminopeptidase(gene name synonym)|uniprotkb:Leucine aminopeptidase 3(gene name synonym)|uniprotkb:Proline aminopeptidase(gene name synonym)|uniprotkb:Prolyl aminopeptidase(gene name synonym)|uniprotkb:Peptidase S(gene name synonym)|uniprotkb:Cysteinylglycine-S-conjugate dipeptidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_056991.2|ensembl:ENSG00000002549(gene)|ensembl:ENST00000226299(transcript)|ensembl:ENST00000618908(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030496"(midbody)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|interpro:IPR008283(Peptidase M17, leucyl aminopeptidase, N-terminal)|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR023042|interpro:IPR043472|mint:P28838 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:BGEwM09Jm/Nn1CwI+QguAqIwGzw9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q16795 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O95169 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q8N4Q1 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-2562213|uniprotkb:A8K3Z9|uniprotkb:Q96AI2|uniprotkb:Q96MY6|ensembl:ENSP00000380122 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:mia40_human(display_long)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001091972.1|refseq:NP_653237.1|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR010625(CHCH)|interpro:IPR039289|mint:Q8N4Q1|rcsb pdb:2K3J|rcsb pdb:2L0Y|reactome:R-HSA-1268020|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|dip:DIP-48483N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O75306 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P19404 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P28331 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9UI09 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P56181 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q96CU9 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-372820|uniprotkb:Q71MG0|uniprotkb:Q9BU39|uniprotkb:Q9UKY9|uniprotkb:B3KN84|uniprotkb:B4DHU2|ensembl:ENSP00000263578 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:fxrd1_human(display_long)|uniprotkb:FP634(orf name)|uniprotkb:FOXRED1(gene name)|psi-mi:FOXRED1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_060017.1|refseq:XP_006718944.1|refseq:XP_016873492.1|refseq:XP_016873493.1|refseq:XP_016873494.1|ensembl:ENSG00000110074(gene)|ensembl:ENST00000263578(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:cAeSafbcQmh6XLk/IrNfsD+KHtA9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O95139 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1053340|uniprotkb:Q6IB84|ensembl:ENSP00000369176|uniprotkb:A8K0Y7|uniprotkb:Q5VYT2 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndub6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B17 subunit(gene name synonym)|uniprotkb:Complex I-B17(gene name synonym)|uniprotkb:NDUFB6(gene name)|psi-mi:NDUFB6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000165264(gene)|ensembl:ENST00000379847(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR019174|mint:O95139|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_877416.1|refseq:NP_002484.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:topkNBeCU1z26byuWjSujC8PshA9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9P0J0 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:O43674 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246293|uniprotkb:Q561V6|ensembl:ENSP00000259037 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndub5_human(display_long)|uniprotkb:NDUFB5(gene name)|psi-mi:NDUFB5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)|uniprotkb:Complex I-SGDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186886.1|refseq:NP_001186887.1|refseq:NP_002483.1|ensembl:ENSG00000136521(gene)|ensembl:ENST00000259037(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:1UrbNq39EsuKHJ2M7tRd8ZmB6uk9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9BU61 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9BUB7 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-726363|uniprotkb:Q9NWY5|uniprotkb:E9PDY9|ensembl:ENSP00000312599 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:tmm70_human(display_long)|uniprotkb:TMEM70(gene name)|psi-mi:TMEM70(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001035703.1|refseq:NP_060336.3|ensembl:ENSG00000175606(gene)|ensembl:ENST00000312184(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR009724(Protein of unknown function DUF1301)|mint:Q9BUB7|go:"GO:0005743"(mitochondrial inner membrane) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:6LHWSQP2W1CRBgylWi8Ncc3X/3E9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9P032 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9Y6M9 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-713654|uniprotkb:Q9UQE8|uniprotkb:B2R8M6|ensembl:ENSP00000276689|ensembl:ENSP00000504235 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndub9_human(display_long)|uniprotkb:LYRM3(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B22 subunit(gene name synonym)|uniprotkb:Complex I-B22(gene name synonym)|uniprotkb:LYR motif-containing protein 3(gene name synonym)|uniprotkb:NDUFB9(gene name)|psi-mi:NDUFB9(display_short)|uniprotkb:UQOR22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 rcsb pdb:5XTH|rcsb pdb:5XTD|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000147684(gene)|ensembl:ENST00000276689(transcript)|ensembl:ENST00000677021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR033034|mint:Q9Y6M9|rcsb pdb:5XTC|refseq:NP_001298097.1|refseq:NP_004996.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:sNQcYhIFMHZA5T6MeeiwAeAJ5Gs9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:P17568 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-1246238|uniprotkb:Q9UI16|uniprotkb:Q6ICN9|ensembl:ENSP00000215565 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ndub7_human(display_long)|uniprotkb:NDUFB7(gene name)|psi-mi:NDUFB7(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B18 subunit(gene name synonym)|uniprotkb:Complex I-B18(gene name synonym)|uniprotkb:Cell adhesion protein SQM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004137.2|ensembl:ENSG00000099795(gene)|ensembl:ENST00000215565(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008698(NADH-ubiquinone oxidoreductase B18 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:9ghtJGrnow8MT1PKXEV2aYuzk0w9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9NPL8 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9H845 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9Y375 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43920 uniprotkb:Q9BQ95 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762907|imex:IM-24050-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:koVU17Y6dUwdIVVVLf41suezY98 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:O00217 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:P28331 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q16718 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q16795 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:O75489 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:O75306 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:P36776 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-357448|ensembl:ENSP00000353826|intact:EBI-1054513|uniprotkb:D6W635|uniprotkb:E5KMH8|uniprotkb:P36777|uniprotkb:Q8N8K8|uniprotkb:Q9UQ95|uniprotkb:B3KPH8|uniprotkb:F5GZ27|intact:EBI-10964236 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:lonm_human(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001263408.1|go:"GO:0070407"(oxidation-dependent protein catabolic process)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027503|mint:P36776|rcsb pdb:2X36|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070182"(DNA polymerase binding)|rcsb pdb:6WYS|rcsb pdb:6WZV|rcsb pdb:6X1M|rcsb pdb:6X27|rcsb pdb:7KRZ|rcsb pdb:7KSL|rcsb pdb:7KSM|rcsb pdb:7NFY|rcsb pdb:7NG4|rcsb pdb:7NG5|rcsb pdb:7NGC|rcsb pdb:7NGF|rcsb pdb:7NGL|rcsb pdb:7NGP|rcsb pdb:7NGQ|ensembl:ENSG00000196365(gene)|ensembl:ENST00000360614(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0009725"(response to hormone)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|refseq:NP_001263409.1|refseq:NP_004784.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:quAPz1dZK2XdoE6WMjQJwFtx53o9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q9H845 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q9BU61 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:O95571 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-715318|uniprotkb:Q96HR0|uniprotkb:Q9H001|ensembl:ENSP00000292147 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:ethe1_human(display_long)|uniprotkb:Ethylmalonic encephalopathy protein 1(gene name synonym)|uniprotkb:Hepatoma subtracted clone one protein(gene name synonym)|uniprotkb:ETHE1(gene name)|psi-mi:ETHE1(display_short)|uniprotkb:HSCO(gene name synonym)|uniprotkb:Sulfur dioxygenase ETHE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_055112.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0042802"(identical protein binding)|go:"GO:0050313"(sulfur dioxygenase activity)|go:"GO:0070813"(hydrogen sulfide metabolic process)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR036866|interpro:IPR044528|rcsb pdb:4CHL|reactome:R-HSA-1614517|ensembl:ENSG00000105755(gene)|ensembl:ENST00000292147(transcript)|go:"GO:0005506"(iron ion binding)|refseq:XP_005258744.1|refseq:NP_001307796.1|refseq:NP_001307797.1|refseq:NP_001307798.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:a7+fXdb2iEny5lCHBrJu+zRvyLs9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q9P032 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q02252 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-2107242|uniprotkb:Q9UKM8|uniprotkb:B2R609|uniprotkb:B4DFS8|uniprotkb:J3KNU8|ensembl:ENSP00000450436 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:mmsa_human(display_long)|uniprotkb:MMSDH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 6 member A1(gene name synonym)|uniprotkb:ALDH6A1(gene name)|psi-mi:ALDH6A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_005580.1|refseq:NP_001265522.1|ensembl:ENSG00000119711(gene)|ensembl:ENST00000553458(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004491"("methylmalonate-semialdehyde dehydrogenase (acylating) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006210"(thymine catabolic process)|go:"GO:0006573"(valine metabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0018478"("malonate-semialdehyde dehydrogenase (acetylating) activity")|go:"GO:0019859"(thymine metabolic process)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0102662"("malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity")|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q02252|reactome:R-HSA-70895 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:9tRJSF7S26Z8N2WYcURXRoOLfFw9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:Q5TEU4 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-10762958|uniprotkb:A8K166|uniprotkb:Q6GPH3|uniprotkb:Q9H6F4|ensembl:ENSP00000367346 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:nduf5_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5(gene name synonym)|uniprotkb:Putative methyltransferase NDUFAF5(gene name synonym)|uniprotkb:NDUFAF5(gene name)|psi-mi:NDUFAF5(display_short)|uniprotkb:C20orf7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001034464.1|refseq:NP_077025.2|ensembl:ENSG00000101247(gene)|ensembl:ENST00000378106(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030961"(peptidyl-arginine hydroxylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q5TEU4|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:BC4jrAunVf7T4Cbrr/sZVFnkrfA9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:O75880 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-6656171|ensembl:ENSP00000255390|uniprotkb:B2RDM0 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:sco1_human(display_long)|uniprotkb:SCO1(gene name)|psi-mi:SCO1(display_short)|uniprotkb:SCOD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000133028(gene)|ensembl:ENST00000255390(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|rcsb pdb:1WP0|rcsb pdb:2GGT|rcsb pdb:2GQK|rcsb pdb:2GQL|rcsb pdb:2GQM|rcsb pdb:2GT5|rcsb pdb:2GT6|rcsb pdb:2GVP|rcsb pdb:2HRF|rcsb pdb:2HRN|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004580.1|dip:DIP-46086N|refseq:XP_005256808.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:oxGxX5mXuGDP5uPIW1vyOtaQHxU9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75251 uniprotkb:P15559 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 intact:EBI-3989435|uniprotkb:B2R5Y9|uniprotkb:Q86UK1|ensembl:ENSP00000319788|uniprotkb:B7ZAD1|uniprotkb:B4DNM7 psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:nqo1_human(display_long)|uniprotkb:NQO1(gene name)|psi-mi:NQO1(display_short)|uniprotkb:DIA4(gene name synonym)|uniprotkb:NMOR1(gene name synonym)|uniprotkb:Azoreductase(gene name synonym)|uniprotkb:DT-diaphorase(gene name synonym)|uniprotkb:Menadione reductase(gene name synonym)|uniprotkb:"NAD(P)H:quinone oxidoreductase 1"(gene name synonym)|uniprotkb:Phylloquinone reductase(gene name synonym)|uniprotkb:Quinone reductase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10762956|imex:IM-24050-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_000894.1|refseq:NP_001020604.1|ensembl:ENSG00000181019(gene)|ensembl:ENST00000320623(transcript)|reactome:R-HSA-350562|go:"GO:0003723"(RNA binding)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006116"(NADH oxidation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008753"("NADPH dehydrogenase (quinone) activity")|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0014075"(response to amine)|go:"GO:0030425"(dendrite)|go:"GO:0032355"(response to estradiol)|go:"GO:0033574"(response to testosterone)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0002931"(response to ischemia)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045471"(response to ethanol)|go:"GO:0050136"("NADH dehydrogenase (quinone) activity")|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0071248"(cellular response to metal ion)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1904844"(response to L-glutamine)|go:"GO:1904880"(response to hydrogen sulfide)|go:"GO:1905395"(response to flavonoid)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR029039|mint:P15559|rcsb pdb:1D4A|rcsb pdb:1DXO|rcsb pdb:1GG5|rcsb pdb:1H66|rcsb pdb:1H69|rcsb pdb:1KBO|rcsb pdb:1KBQ|rcsb pdb:1QBG|rcsb pdb:2F1O|rcsb pdb:3JSX|rcsb pdb:4CET|rcsb pdb:4CF6|rcsb pdb:5A4K|rcsb pdb:5EA2|rcsb pdb:5EAI|rcsb pdb:5FUQ|rcsb pdb:6FY4|rcsb pdb:6LLC|refseq:NP_001020605.1|dip:DIP-24210N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rogid:FTxQttmBGSHV/ICU3eacckUXQ7s9606 rigid:QhFHFfFhlH59svvsIL2z2bz0XFQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O75438 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-744216|uniprotkb:A0AV68|ensembl:ENSP00000330787|ensembl:ENSP00000450776|ensembl:ENSP00000451090|ensembl:ENSP00000475170 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndub1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MNLL subunit(gene name synonym)|uniprotkb:Complex I-MNLL(gene name synonym)|uniprotkb:NDUFB1(gene name)|psi-mi:NDUFB1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004536.2|ensembl:ENSG00000183648(gene)|ensembl:ENST00000329559(transcript)|ensembl:ENST00000553514(transcript)|ensembl:ENST00000555441(transcript)|ensembl:ENST00000605997(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012575(MNLL subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:FU3iytC6Yu5qzxy8Yim4y6wSVqc9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O00217 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P17568 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246238|uniprotkb:Q9UI16|uniprotkb:Q6ICN9|ensembl:ENSP00000215565 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndub7_human(display_long)|uniprotkb:NDUFB7(gene name)|psi-mi:NDUFB7(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B18 subunit(gene name synonym)|uniprotkb:Complex I-B18(gene name synonym)|uniprotkb:Cell adhesion protein SQM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004137.2|ensembl:ENSG00000099795(gene)|ensembl:ENST00000215565(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008698(NADH-ubiquinone oxidoreductase B18 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:9ghtJGrnow8MT1PKXEV2aYuzk0w9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O14561 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246261|uniprotkb:Q9UNV1|uniprotkb:B2R4M1|ensembl:ENSP00000007516|ensembl:ENSP00000458770 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:acpm_human(display_long)|uniprotkb:NDUFAB1(gene name)|psi-mi:NDUFAB1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:CI-SDAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004994.1|ensembl:ENSG00000004779(gene)|ensembl:ENST00000007516(transcript)|ensembl:ENST00000570319(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|rcsb pdb:2DNW|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|rcsb pdb:6ODD|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-389661|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-77289 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:I3NqGP/VaZP/6cwDFwVIgmu8lP89606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:Q8NE86 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-6552124|ensembl:ENSP00000362144|uniprotkb:B2RDF3|uniprotkb:B3KXV7|uniprotkb:Q96FL3 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:mcu_human(display_long)|uniprotkb:MCU(gene name)|psi-mi:MCU(display_short)|uniprotkb:C10orf42(gene name synonym)|uniprotkb:CCDC109A(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 109A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1990246"(uniplex complex)|interpro:IPR006769(Protein of unknown function DUF607)|interpro:IPR039055|rcsb pdb:4XSJ|rcsb pdb:4XTB|rcsb pdb:5BZ6|rcsb pdb:5KUE|rcsb pdb:5KUG|rcsb pdb:5KUI|rcsb pdb:5KUJ|rcsb pdb:6JG0|rcsb pdb:6K7X|rcsb pdb:6K7Y|rcsb pdb:6KVX|rcsb pdb:6O58|rcsb pdb:6O5B|rcsb pdb:6WDN|rcsb pdb:6WDO|rcsb pdb:6XJV|rcsb pdb:6XJX|reactome:R-HSA-8949215|reactome:R-HSA-8949664|go:"GO:0019722"(calcium-mediated signaling)|ensembl:ENSG00000156026(gene)|ensembl:ENST00000373053(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0015292"(uniporter activity)|refseq:NP_001257608.1|refseq:NP_001257609.1|refseq:NP_612366.1|dip:DIP-60468N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:t2fSATmrk7IEC0nMpquAoPB3CHs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P47985 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O95299 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246361|uniprotkb:Q8WXC9|ensembl:ENSP00000252711|ensembl:ENSP00000503956|ensembl:ENSP00000504765 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduaa_human(display_long)|uniprotkb:NDUFA10(gene name)|psi-mi:NDUFA10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004535.1|ensembl:ENSG00000130414(gene)|ensembl:ENST00000252711(transcript)|ensembl:ENST00000676929(transcript)|ensembl:ENST00000678158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:O95299|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:8jwJPJ0rD9H7A4AzxPd186tpXYs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O95182 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:Q9UI09 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O75489 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P28331 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:Q9NX14 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P49821 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O43674 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246293|uniprotkb:Q561V6|ensembl:ENSP00000259037 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndub5_human(display_long)|uniprotkb:NDUFB5(gene name)|psi-mi:NDUFB5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)|uniprotkb:Complex I-SGDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001186886.1|refseq:NP_001186887.1|refseq:NP_002483.1|ensembl:ENSG00000136521(gene)|ensembl:ENST00000259037(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:1UrbNq39EsuKHJ2M7tRd8ZmB6uk9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O75251 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:Q16718 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:Q9UDW1 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1224495|uniprotkb:B5MCM5|uniprotkb:Q9T2V6|ensembl:ENSP00000332887 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:qcr9_human(display_long)|uniprotkb:UQCR10(gene name)|psi-mi:UQCR10(display_short)|uniprotkb:HSPC119(orf name)|uniprotkb:UCRC(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 7.2 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 7 kDa protein(gene name synonym)|uniprotkb:Complex III subunit X(gene name synonym)|uniprotkb:Complex III subunit 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001003684.1|refseq:NP_037519.2|interpro:IPR036656|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|ensembl:ENSG00000184076(gene)|ensembl:ENST00000330029(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR008027(Ubiquinol-cytochrome C reductase, UQCRX/QCR9-like) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:DDANQjwNz4ft+SVqOawiqaxueJk9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O43676 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-718365|uniprotkb:Q6IB80|ensembl:ENSP00000237889|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000410600|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndub3_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NDUFB3(gene name)|psi-mi:NDUFB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_002482.1|refseq:XP_011509532.1|refseq:XP_016859675.1|refseq:NP_001244031.1|ensembl:ENSP00000237889|ensembl:ENSP00000410600|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208|ensembl:ENSG00000119013(gene)|ensembl:ENST00000237889(transcript)|ensembl:ENST00000433898(transcript)|ensembl:ENST00000450023(transcript)|ensembl:ENST00000454214(transcript)|ensembl:ENST00000682325(transcript)|ensembl:ENST00000684175(transcript)|ensembl:ENST00000684420(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:APgw3aIZyyqiPCXMFJ9dUYPQhVE9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O75306 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O43678 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O95168 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O95169 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O43181 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O96000 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P00156 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1224441|uniprotkb:Q34786|uniprotkb:Q8HBR6|uniprotkb:Q8HNQ0|uniprotkb:Q8HNQ1|uniprotkb:Q8HNQ9|uniprotkb:Q8HNR4|uniprotkb:Q8HNR7|uniprotkb:Q8W7V8|uniprotkb:Q8WCV9|uniprotkb:Q8WCY2|uniprotkb:Q8WCY7|uniprotkb:Q8WCY8|uniprotkb:Q9B1A6|uniprotkb:Q9B1B6|uniprotkb:Q9B1B8|uniprotkb:Q9B1D4|uniprotkb:Q9B1X6|uniprotkb:Q9B2V0|uniprotkb:Q9B2V8|uniprotkb:Q9B2W0|uniprotkb:Q9B2W3|uniprotkb:Q9B2W8|uniprotkb:Q9B2X1|uniprotkb:Q9B2X7|uniprotkb:Q9B2X9|uniprotkb:Q9B2Y3|uniprotkb:Q9B2Z0|uniprotkb:Q9B2Z4|uniprotkb:Q9T6H6|uniprotkb:Q9T9Y0|uniprotkb:Q9TEH4|ensembl:ENSP00000354554 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:cyb_human(display_long)|uniprotkb:MT-CYB(gene name)|psi-mi:MT-CYB(display_short)|uniprotkb:COB(gene name synonym)|uniprotkb:CYTB(gene name synonym)|uniprotkb:MTCYB(gene name synonym)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome b subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 3(gene name synonym)|uniprotkb:Complex III subunit 3(gene name synonym)|uniprotkb:Complex III subunit III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:YP_003024038.1|ensembl:ENSG00000198727(gene)|ensembl:ENST00000361789(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009408"(response to heat)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033590"(response to cobalamin)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR005798(Cytochrome b/b6, C-terminal)|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027387|interpro:IPR030689|interpro:IPR036150|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:pmuj0KISx06AK4PF7DVEwDVsV9M9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P19404 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P56181 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P03915 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:P56556 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O75380 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-719854|ensembl:ENSP00000274137 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:O43402 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q16795 uniprotkb:Q86Y39 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763002|imex:IM-24050-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rigid:Mp7b/A2DhjSIJZ7+komE0RntIFo false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O43920 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O00217 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O75380 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-719854|ensembl:ENSP00000274137 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P03891 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246202|uniprotkb:Q34769|uniprotkb:Q9TGI0|uniprotkb:Q9TGI1|uniprotkb:Q9TGI2|uniprotkb:Q9TGI3|uniprotkb:Q9TGI4|ensembl:ENSP00000355046 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nu2m_human(display_long)|uniprotkb:MT-ND2(gene name)|psi-mi:MT-ND2(display_short)|uniprotkb:MTND2(gene name synonym)|uniprotkb:NADH2(gene name synonym)|uniprotkb:ND2(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024027.1|ensembl:ENSG00000198763(gene)|ensembl:ENST00000361453(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003917(NADH-ubiquinone oxidoreductase, chain 2)|interpro:IPR010933(NADH dehydrogenase subunit 2, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:GKiEviD5+IEk1TCxgEvUyw6Ys6s9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O14561 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246261|uniprotkb:Q9UNV1|uniprotkb:B2R4M1|ensembl:ENSP00000007516|ensembl:ENSP00000458770 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:acpm_human(display_long)|uniprotkb:NDUFAB1(gene name)|psi-mi:NDUFAB1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:CI-SDAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004994.1|ensembl:ENSG00000004779(gene)|ensembl:ENST00000007516(transcript)|ensembl:ENST00000570319(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|rcsb pdb:2DNW|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|rcsb pdb:6ODD|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-389661|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-77289 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:I3NqGP/VaZP/6cwDFwVIgmu8lP89606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O75251 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P03905 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q9H9J2 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-713619|uniprotkb:Q53S16|uniprotkb:Q6IA62|uniprotkb:Q9H821|ensembl:ENSP00000258383|intact:EBI-21356011 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:rm44_human(display_long)|uniprotkb:MRPL44(gene name)|psi-mi:MRPL44(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL44(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000135900(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR044444|mint:Q9H9J2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|ensembl:ENST00000258383(transcript)|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_075066.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:YNUNu4UGyhAuaSChEzFXCw2k7wk9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q9UI09 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O75489 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P14927 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-743128|ensembl:ENSP00000287022|uniprotkb:Q6FGD1|uniprotkb:E5RJU0 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:qcr7_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase complex 14 kDa protein(gene name synonym)|uniprotkb:Complex III subunit 7(gene name synonym)|uniprotkb:Complex III subunit VII(gene name synonym)|uniprotkb:QP-C(gene name synonym)|uniprotkb:UQCRB(gene name)|psi-mi:UQCRB(display_short)|uniprotkb:UQBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000156467(gene)|ensembl:ENST00000287022(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0009060"(aerobic respiration)|interpro:IPR003197(Cytochrome bd ubiquinol oxidase, 14 kDa subunit)|interpro:IPR036544|mint:P14927|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|refseq:NP_006285.1|refseq:NP_001186904.1|refseq:NP_001241681.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:JEa3rOlDB4nVyYDniZrcnF9b1Wg9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q9NX14 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P10606 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001853.2|ensembl:ENSG00000135940(gene)|ensembl:ENST00000258424(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P49821 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P47985 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O43674 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246293|uniprotkb:Q561V6|ensembl:ENSP00000259037 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndub5_human(display_long)|uniprotkb:NDUFB5(gene name)|psi-mi:NDUFB5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)|uniprotkb:Complex I-SGDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186886.1|refseq:NP_001186887.1|refseq:NP_002483.1|ensembl:ENSG00000136521(gene)|ensembl:ENST00000259037(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:1UrbNq39EsuKHJ2M7tRd8ZmB6uk9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O43678 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O95168 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P28331 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O95299 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246361|uniprotkb:Q8WXC9|ensembl:ENSP00000252711|ensembl:ENSP00000503956|ensembl:ENSP00000504765 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nduaa_human(display_long)|uniprotkb:NDUFA10(gene name)|psi-mi:NDUFA10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004535.1|ensembl:ENSG00000130414(gene)|ensembl:ENST00000252711(transcript)|ensembl:ENST00000676929(transcript)|ensembl:ENST00000678158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:O95299|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:8jwJPJ0rD9H7A4AzxPd186tpXYs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q9UDW1 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1224495|uniprotkb:B5MCM5|uniprotkb:Q9T2V6|ensembl:ENSP00000332887 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:qcr9_human(display_long)|uniprotkb:UQCR10(gene name)|psi-mi:UQCR10(display_short)|uniprotkb:HSPC119(orf name)|uniprotkb:UCRC(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 7.2 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 7 kDa protein(gene name synonym)|uniprotkb:Complex III subunit X(gene name synonym)|uniprotkb:Complex III subunit 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001003684.1|refseq:NP_037519.2|interpro:IPR036656|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|ensembl:ENSG00000184076(gene)|ensembl:ENST00000330029(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR008027(Ubiquinol-cytochrome C reductase, UQCRX/QCR9-like) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:DDANQjwNz4ft+SVqOawiqaxueJk9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q9Y4W6 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O43676 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-718365|uniprotkb:Q6IB80|ensembl:ENSP00000237889|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000410600|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndub3_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NDUFB3(gene name)|psi-mi:NDUFB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002482.1|refseq:XP_011509532.1|refseq:XP_016859675.1|refseq:NP_001244031.1|ensembl:ENSP00000237889|ensembl:ENSP00000410600|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208|ensembl:ENSG00000119013(gene)|ensembl:ENST00000237889(transcript)|ensembl:ENST00000433898(transcript)|ensembl:ENST00000450023(transcript)|ensembl:ENST00000454214(transcript)|ensembl:ENST00000682325(transcript)|ensembl:ENST00000684175(transcript)|ensembl:ENST00000684420(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:APgw3aIZyyqiPCXMFJ9dUYPQhVE9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q16718 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O75306 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O95169 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P35558 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-3927265|uniprotkb:B4DT64|uniprotkb:Q9UJD2|uniprotkb:A8K437|uniprotkb:Q8TCA3|ensembl:ENSP00000319814 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:pckgc_human(display_long)|uniprotkb:PCK1(gene name)|psi-mi:PCK1(display_short)|uniprotkb:PEPCK1(gene name synonym)|uniprotkb:Serine-protein kinase PCK1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 rcsb pdb:1M51|rcsb pdb:2GMV|reactome:R-HSA-2161541|rcsb pdb:1NHX|reactome:R-HSA-381340|reactome:R-HSA-70263|reactome:R-HSA-9615017|reactome:R-HSA-9632974|ensembl:ENSG00000124253(gene)|ensembl:ENST00000319441(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004613"("phosphoenolpyruvate carboxykinase (GTP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0007568"(aging)|go:"GO:0014823"(response to activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019003"(GDP binding)|go:"GO:0019543"(propionate catabolic process)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042594"(response to starvation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0046327"(glycerol biosynthetic process from pyruvate)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0061402"(positive regulation of transcription from RNA polymerase II promoter in response to acidic pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0106264"("protein serine kinase activity (using GTP as donor)")|go:"GO:1904640"(response to methionine)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:P35558|rcsb pdb:1KHB|rcsb pdb:1KHE|rcsb pdb:1KHF|go:"GO:0005737"(cytoplasm)|rcsb pdb:1KHG|refseq:NP_002582.3 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:1ogsuTnND1a8emjt3Duqc8lczf09606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q9H3K2 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-2868909|uniprotkb:A8K9Z9|uniprotkb:Q5VT95|uniprotkb:O95894|uniprotkb:Q9H0P2|uniprotkb:D3DWE0|ensembl:ENSP00000361207 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ghitm_human(display_long)|uniprotkb:GHITM(gene name)|psi-mi:GHITM(display_short)|uniprotkb:DERP2(gene name synonym)|uniprotkb:MICS1(gene name synonym)|uniprotkb:TMBIM5(gene name synonym)|uniprotkb:Dermal papilla-derived protein 2(gene name synonym)|uniprotkb:Mitochondrial morphology and cristae structure 1(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 5(gene name synonym)|uniprotkb:My021(orf name)|uniprotkb:UNQ244/PRO281(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_055209.2|ensembl:ENSG00000165678(gene)|ensembl:ENST00000372134(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR006214(Protein of unknown function UPF0005)|interpro:IPR035871|mint:Q9H3K2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:HlNwyLRPIHhjs1bYJQE+IqZ00qc9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O95139 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1053340|uniprotkb:Q6IB84|ensembl:ENSP00000369176|uniprotkb:A8K0Y7|uniprotkb:Q5VYT2 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndub6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B17 subunit(gene name synonym)|uniprotkb:Complex I-B17(gene name synonym)|uniprotkb:NDUFB6(gene name)|psi-mi:NDUFB6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000165264(gene)|ensembl:ENST00000379847(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR019174|mint:O95139|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_877416.1|refseq:NP_002484.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:topkNBeCU1z26byuWjSujC8PshA9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:O43181 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P19404 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q96TA2 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P56181 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P56556 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P03915 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q86X76 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-716301|uniprotkb:O76091|uniprotkb:B1AQP3|uniprotkb:D3DVF4|ensembl:ENSP00000356988 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:nit1_human(display_long)|uniprotkb:Nitrilase homolog 1(gene name synonym)|uniprotkb:NIT1(gene name)|psi-mi:NIT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001172021.1|refseq:NP_001172022.1|refseq:NP_001172023.1|refseq:NP_005591.1|ensembl:ENST00000368007|ensembl:ENSP00000356986|ensembl:ENST00000368008|ensembl:ENSP00000356987|ensembl:ENSP00000356988|ensembl:ENST00000392190|ensembl:ENSP00000376028|refseq:XP_005245273.1|ensembl:ENSG00000158793(gene)|ensembl:ENST00000368009(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0043605"(cellular amide catabolic process)|go:"GO:0110050"(deaminated glutathione amidase activity)|interpro:IPR001110(Protein of unknown function UPF0012, conserved site)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|interpro:IPR036526 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:Tt+RiYdwfe/+RD7509CdCMNHnvk9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:P51970 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1237250|uniprotkb:B1AM93|uniprotkb:Q9Y6N0|ensembl:ENSP00000362873 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndua8_human(display_long)|uniprotkb:NDUFA8(gene name)|psi-mi:NDUFA8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_055037.1|ensembl:ENSG00000119421(gene)|ensembl:ENST00000373768(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:P51970|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:buGk0RR4rNyaFDdsjenBqzYzlMs9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q86Y39 uniprotkb:Q16795 intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763043|imex:IM-24050-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/07/05 rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:GwE0xIPikpCh9K1bgtkMkosJ9Sc false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:O43676 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-718365|uniprotkb:Q6IB80|ensembl:ENSP00000237889|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000410600|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndub3_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NDUFB3(gene name)|psi-mi:NDUFB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_002482.1|refseq:XP_011509532.1|refseq:XP_016859675.1|refseq:NP_001244031.1|ensembl:ENSP00000237889|ensembl:ENSP00000410600|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208|ensembl:ENSG00000119013(gene)|ensembl:ENST00000237889(transcript)|ensembl:ENST00000433898(transcript)|ensembl:ENST00000450023(transcript)|ensembl:ENST00000454214(transcript)|ensembl:ENST00000682325(transcript)|ensembl:ENST00000684175(transcript)|ensembl:ENST00000684420(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:APgw3aIZyyqiPCXMFJ9dUYPQhVE9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q16795 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:P28331 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9P032 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9UI09 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:O95298 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1246172|uniprotkb:Q9UBJ9|uniprotkb:Q6FIH8|uniprotkb:Q549M5|uniprotkb:E9PNU8|uniprotkb:E9PRB2|ensembl:ENSP00000281031 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:nduc2_human(display_long)|uniprotkb:NDUFC2(gene name)|psi-mi:NDUFC2(display_short)|uniprotkb:HLC1(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5b(gene name synonym)|uniprotkb:Complex I-B14.5b(gene name synonym)|uniprotkb:Human lung cancer oncogene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_004540.1|refseq:NP_001190983.1|refseq:NP_001190984.1|ensembl:ENSG00000151366(gene)|ensembl:ENST00000281031(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005886"(plasma membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR009423(NADH-ubiquinone oxidoreductase subunit b14.5b)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6798695|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:IILkKsJHyRjCMZJ6z//WjdRXQUQ9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:P49821 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:O75489 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q16718 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:A6NK97 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-10763173|uniprotkb:B9EJB2|uniprotkb:Q6ZN88 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:s22ak_human(display_long)|uniprotkb:SLC22A20P(gene name)|psi-mi:SLC22A20P(display_short)|uniprotkb:OAT6(gene name synonym)|uniprotkb:Organic anion transporter 6(gene name synonym)|uniprotkb:SLC22A20(gene name synonym)|uniprotkb:Solute carrier family 22 member 20 pseudogene(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N interpro:IPR020846|interpro:IPR005828(General substrate transporter)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR036259|refseq:NP_001004326.4 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:a17Psrtxbm5qxt5P23viTeCq6sg9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q96S37 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-10763127|uniprotkb:B7WPG1|uniprotkb:G3XAN7|uniprotkb:Q19PF7|uniprotkb:Q19PF8|uniprotkb:Q19PF9|uniprotkb:Q19PG0|uniprotkb:Q6UXW3|uniprotkb:Q96DT2|intact:EBI-28985430|ensembl:ENSP00000366797 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:s22ac_human(display_long)|uniprotkb:Organic anion transporter 4-like protein(gene name synonym)|uniprotkb:Renal-specific transporter(gene name synonym)|uniprotkb:Urate anion exchanger 1(gene name synonym)|uniprotkb:UNQ6453/PRO34004(orf name)|uniprotkb:SLC22A12(gene name)|psi-mi:SLC22A12(display_short)|uniprotkb:OATL4(gene name synonym)|uniprotkb:URAT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_001263255.1|refseq:NP_001263256.1|refseq:NP_653186.2|refseq:NP_700357.1|ensembl:ENST00000336464|ensembl:ENSP00000336836|ensembl:ENST00000377567|ensembl:ENSP00000366790|ensembl:ENST00000377572|ensembl:ENSP00000366795|ensembl:ENSP00000366797|ensembl:ENST00000473690|ensembl:ENSP00000438437|ensembl:ENSG00000197891(gene)|ensembl:ENST00000377574(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015747"(urate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0042493"|go:"GO:0046415"(urate metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-561048|reactome:R-HSA-5619071 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:R8fgTbaoB+jVUatZkRMiOcXwig09606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:P18859 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:P47985 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9Y4W6 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:O14925 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1047996|uniprotkb:Q53FF8|uniprotkb:Q6P5S5|uniprotkb:Q5T1E6|ensembl:ENSP00000464522 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:tim23_human(display_long)|uniprotkb:TIMM23(gene name)|psi-mi:TIMM23(display_short)|uniprotkb:TIM23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_006318.1|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005681(Mitochondrial import inner membrane translocase, subunit Tim23)|mint:O14925|reactome:R-HSA-1268020|ensembl:ENSG00000265354(gene)|ensembl:ENST00000580018(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:Hmu/kwfaPLGFGYBJH0oue7JDYqM9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:O75251 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:O75306 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9BU61 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9NNW7 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-10763091|uniprotkb:O95840|uniprotkb:Q96IJ2|uniprotkb:Q9H2Z5|uniprotkb:Q9NZV3|uniprotkb:Q9NZV4|uniprotkb:Q9P2Y0|uniprotkb:Q9P2Y1|uniprotkb:Q9UQU8|ensembl:ENSP00000383365 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:trxr2_human(display_long)|uniprotkb:Selenoprotein Z(gene name synonym)|uniprotkb:TR-beta(gene name synonym)|uniprotkb:Thioredoxin reductase TR3(gene name synonym)|uniprotkb:TXNRD2(gene name)|psi-mi:TXNRD2(display_short)|uniprotkb:KIAA1652(gene name synonym)|uniprotkb:TRXR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_006431.2|ensembl:ENSG00000184470(gene)|ensembl:ENST00000400521(transcript)|go:"GO:0000305"(response to oxygen radical)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:1W1E|reactome:R-HSA-3299685 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:Ox9OHgRY9QSgL+ib9RKDVkIu7b49606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:P12236 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q96TA2 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q8IUX1 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-2800657|uniprotkb:Q32Q09|uniprotkb:Q9NZ29|uniprotkb:Q96EP3|uniprotkb:Q8WVU3|uniprotkb:A8K535|uniprotkb:A8MSS0|ensembl:ENSP00000351737 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:t126b_human(display_long)|uniprotkb:TMEM126B(gene name)|psi-mi:TMEM126B(display_short)|uniprotkb:Transmembrane protein 126B(gene name synonym)|uniprotkb:HT007(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:XP_011543467.1|refseq:NP_001180467.1|refseq:NP_060950.3|refseq:NP_001243475.1|ensembl:ENSG00000171204(gene)|ensembl:ENST00000358867(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009801(Protein of unknown function DUF1370)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:eQNEaTeYOl8NJlnxhrTi3R6m66I9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9H845 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9BQ95 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9NPL8 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P0J0 uniprotkb:Q9Y375 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763087|imex:IM-24050-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:LPHxUg+m/yiWnKKo3AdDHL5EP+k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:O75489 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9NPL8 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9UI09 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:P28331 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9NX14 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q5T9A4 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9BYD6 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-5325394|ensembl:ENSP00000315017|uniprotkb:A6NG03|uniprotkb:Q4W5B8|uniprotkb:Q6IAG4|uniprotkb:Q96BW3|uniprotkb:Q9H793|uniprotkb:Q9NRL5 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:rm01_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:BM-022(orf name)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 ensembl:ENSG00000169288(gene)|ensembl:ENST00000315567(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:Q9BYD6|rcsb pdb:7A5K|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011530500.1|refseq:XP_011530501.1|refseq:NP_064621.3 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:S5t4UAM2nDToXMl6lV3gh6Ecef09606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9P289 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9BU61 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9H307 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q8IUX1 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-2800657|uniprotkb:Q32Q09|uniprotkb:Q9NZ29|uniprotkb:Q96EP3|uniprotkb:Q8WVU3|uniprotkb:A8K535|uniprotkb:A8MSS0|ensembl:ENSP00000351737 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:t126b_human(display_long)|uniprotkb:TMEM126B(gene name)|psi-mi:TMEM126B(display_short)|uniprotkb:Transmembrane protein 126B(gene name synonym)|uniprotkb:HT007(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 refseq:XP_011543467.1|refseq:NP_001180467.1|refseq:NP_060950.3|refseq:NP_001243475.1|ensembl:ENSG00000171204(gene)|ensembl:ENST00000358867(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009801(Protein of unknown function DUF1370)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:eQNEaTeYOl8NJlnxhrTi3R6m66I9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9H845 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y375 uniprotkb:Q9BQ95 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763218|imex:IM-24050-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2018/04/06 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:IX36SUSUkSQYWpxguFPu8cjimTQ false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:P03905 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:O00217 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:P49821 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:O75489 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:O95182 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:O75306 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:Q16795 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:P19404 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:P28331 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O75380 uniprotkb:P56181 intact:EBI-719854|ensembl:ENSP00000274137 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763250|imex:IM-24050-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:V5Q0XqTTmLLB6nK3Ovf/kBfp138 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:O95168 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:P03915 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:O75306 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:O00217 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:O75489 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:O43678 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:P03886 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:Q16795 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:P56181 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:Q9UI09 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:P28331 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:P19404 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P49821 uniprotkb:P55809 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 intact:EBI-2687150|uniprotkb:B7Z528|uniprotkb:B2R5V2|ensembl:ENSP00000196371 psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:scot1_human(display_long)|uniprotkb:OXCT(gene name synonym)|uniprotkb:SCOT(gene name synonym)|uniprotkb:OXCT1(gene name)|psi-mi:OXCT1(display_short)|uniprotkb:3-oxoacid CoA-transferase 1(gene name synonym)|uniprotkb:"Somatic-type succinyl-CoA:3-oxoacid CoA-transferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763293|imex:IM-24050-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 refseq:NP_000427.1|ensembl:ENSG00000083720(gene)|ensembl:ENST00000196371(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042182"(ketone catabolic process)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|rcsb pdb:3DLX|reactome:R-HSA-77108 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rogid:9kyVQbY3sPBRAfJkkF5HhHZg31c9606 rigid:RXjbGaOoY2TqXO9dPE73jCl4IQs false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:O75489 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:Q9UI09 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:O75306 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:P03915 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:Q16795 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:Q9P0J0 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:P56181 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:P49821 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P19404 uniprotkb:P28331 intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763329|imex:IM-24050-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2 refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 rigid:nLqZLk2VofuejVKKLwwFmR9nGs8 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:O75489 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408 - - crc64:C058D62779BEF17B figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q8IWF2 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:P03923 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1246099|uniprotkb:Q34774|uniprotkb:Q8HG30|intact:EBI-28985719|ensembl:ENSP00000354665 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:nu6m_human(display_long)|uniprotkb:MT-ND6(gene name)|psi-mi:MT-ND6(display_short)|uniprotkb:MTND6(gene name synonym)|uniprotkb:NADH6(gene name synonym)|uniprotkb:ND6(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:YP_003024037.1|ensembl:ENSP00000354665|ensembl:ENSG00000198695(gene)|ensembl:ENST00000361681(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070469"(respirasome)|interpro:IPR001457(NADH-ubiquinone/plastoquinone oxidoreductase, chain 6)|mint:P03923|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:RuqWsG2c5WKw60frXqUSTzUY1c09606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q9NPL8 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q9P0J0 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:O96000 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:O75251 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:O00217 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:P51970 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1237250|uniprotkb:B1AM93|uniprotkb:Q9Y6N0|ensembl:ENSP00000362873 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ndua8_human(display_long)|uniprotkb:NDUFA8(gene name)|psi-mi:NDUFA8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_055037.1|ensembl:ENSG00000119421(gene)|ensembl:ENST00000373768(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:P51970|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:buGk0RR4rNyaFDdsjenBqzYzlMs9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q9H845 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q9P032 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:O75306 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:O43920 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q9BQ95 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q5TEU4 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-10762958|uniprotkb:A8K166|uniprotkb:Q6GPH3|uniprotkb:Q9H6F4|ensembl:ENSP00000367346 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:nduf5_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5(gene name synonym)|uniprotkb:Putative methyltransferase NDUFAF5(gene name synonym)|uniprotkb:NDUFAF5(gene name)|psi-mi:NDUFAF5(display_short)|uniprotkb:C20orf7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_001034464.1|refseq:NP_077025.2|ensembl:ENSG00000101247(gene)|ensembl:ENST00000378106(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030961"(peptidyl-arginine hydroxylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q5TEU4|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:BC4jrAunVf7T4Cbrr/sZVFnkrfA9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BU61 uniprotkb:Q9Y375 intact:EBI-2114801|ensembl:ENSP00000323076 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763353|imex:IM-24050-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:+OumV4ni21XDr9qewQXgbNJeK2k false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O43674 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246293|uniprotkb:Q561V6|ensembl:ENSP00000259037 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndub5_human(display_long)|uniprotkb:NDUFB5(gene name)|psi-mi:NDUFB5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)|uniprotkb:Complex I-SGDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001186886.1|refseq:NP_001186887.1|refseq:NP_002483.1|ensembl:ENSG00000136521(gene)|ensembl:ENST00000259037(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:1UrbNq39EsuKHJ2M7tRd8ZmB6uk9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q8WWC4 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q8N2C7 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2952637|ensembl:ENSP00000391088|uniprotkb:B4DZB3|uniprotkb:Q96JI4|uniprotkb:B2RN50|uniprotkb:B4DQY9|uniprotkb:C4IXS8|uniprotkb:Q96SS0|uniprotkb:C9J1U3 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:unc80_human(display_long)|uniprotkb:UNC80(gene name)|psi-mi:UNC80(display_short)|uniprotkb:C2orf21(gene name synonym)|uniprotkb:KIAA1843(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000144406(gene)|ensembl:ENST00000439458(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0034703"(cation channel complex)|go:"GO:0055080"(cation homeostasis)|interpro:IPR031542|reactome:R-HSA-2672351|refseq:NP_115893.1|refseq:NP_872393.3 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:PeEb0RQz+N6nC7KqsJx0k1ka5pU9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9NX40 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|ensembl:ENSP00000264312|ensembl:ENSP00000370882|ensembl:ENSP00000423002|ensembl:ENSP00000423909|uniprotkb:G8JLN7 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|ensembl:ENSG00000109180(gene)|ensembl:ENST00000264312(transcript)|ensembl:ENST00000381473(transcript)|ensembl:ENST00000508293(transcript)|ensembl:ENST00000513391(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|refseq:XP_016863818.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P56181 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9UI09 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P03891 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246202|uniprotkb:Q34769|uniprotkb:Q9TGI0|uniprotkb:Q9TGI1|uniprotkb:Q9TGI2|uniprotkb:Q9TGI3|uniprotkb:Q9TGI4|ensembl:ENSP00000355046 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nu2m_human(display_long)|uniprotkb:MT-ND2(gene name)|psi-mi:MT-ND2(display_short)|uniprotkb:MTND2(gene name synonym)|uniprotkb:NADH2(gene name synonym)|uniprotkb:ND2(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:YP_003024027.1|ensembl:ENSG00000198763(gene)|ensembl:ENST00000361453(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003917(NADH-ubiquinone oxidoreductase, chain 2)|interpro:IPR010933(NADH dehydrogenase subunit 2, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:GKiEviD5+IEk1TCxgEvUyw6Ys6s9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P56385 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q16795 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9Y4W6 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P49821 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O00217 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q8IUX1 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2800657|uniprotkb:Q32Q09|uniprotkb:Q9NZ29|uniprotkb:Q96EP3|uniprotkb:Q8WVU3|uniprotkb:A8K535|uniprotkb:A8MSS0|ensembl:ENSP00000351737 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:t126b_human(display_long)|uniprotkb:TMEM126B(gene name)|psi-mi:TMEM126B(display_short)|uniprotkb:Transmembrane protein 126B(gene name synonym)|uniprotkb:HT007(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:XP_011543467.1|refseq:NP_001180467.1|refseq:NP_060950.3|refseq:NP_001243475.1|ensembl:ENSG00000171204(gene)|ensembl:ENST00000358867(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009801(Protein of unknown function DUF1370)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:eQNEaTeYOl8NJlnxhrTi3R6m66I9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O60220 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O95168 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P53701 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-10763431|uniprotkb:B3KUS1|uniprotkb:Q502X8|ensembl:ENSP00000326579|ensembl:ENSP00000370139|ensembl:ENSP00000370140 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:cchl_human(display_long)|uniprotkb:Cytochrome c-type heme lyase(gene name synonym)|uniprotkb:HCCS(gene name)|psi-mi:HCCS(display_short)|uniprotkb:CCHL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001116080.1|refseq:NP_001165462.1|refseq:NP_005324.3|ensembl:ENSG00000004961(gene)|ensembl:ENST00000321143(transcript)|ensembl:ENST00000380762(transcript)|ensembl:ENST00000380763(transcript)|go:"GO:0004408"(holocytochrome-c synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000511(Cytochrome c and c1 haem-lyase)|mint:P53701 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:bJhUeXcA+kpWK7qF33e5hBwQops9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O14548 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-743578|uniprotkb:Q9P118|ensembl:ENSP00000234301|ensembl:ENSP00000367938 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:cox7r_human(display_long)|uniprotkb:Cytochrome c oxidase subunit VIIa-related protein(gene name synonym)|uniprotkb:COX7a-related protein(gene name synonym)|uniprotkb:EB1(gene name synonym)|uniprotkb:COX7RP(gene name synonym)|uniprotkb:COX7A2L(gene name)|psi-mi:COX7A2L(display_short)|uniprotkb:COX7AR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_004709.2|refseq:NP_001305965.1|refseq:NP_001305969.1|ensembl:ENSG00000115944(gene)|ensembl:ENST00000234301(transcript)|ensembl:ENST00000378669(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR017267(Cytochrome c oxidase subunit VIIa-related, mitochondrial)|interpro:IPR036539|interpro:IPR039297|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:qJHxwSXSwyenuqJmKPhQ3R76aqE9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O75251 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q96TA2 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9H845 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9Y6M9 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-713654|uniprotkb:Q9UQE8|uniprotkb:B2R8M6|ensembl:ENSP00000276689|ensembl:ENSP00000504235 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndub9_human(display_long)|uniprotkb:LYRM3(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B22 subunit(gene name synonym)|uniprotkb:Complex I-B22(gene name synonym)|uniprotkb:LYR motif-containing protein 3(gene name synonym)|uniprotkb:NDUFB9(gene name)|psi-mi:NDUFB9(display_short)|uniprotkb:UQOR22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 rcsb pdb:5XTH|rcsb pdb:5XTD|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000147684(gene)|ensembl:ENST00000276689(transcript)|ensembl:ENST00000677021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR033034|mint:Q9Y6M9|rcsb pdb:5XTC|refseq:NP_001298097.1|refseq:NP_004996.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:sNQcYhIFMHZA5T6MeeiwAeAJ5Gs9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O96000 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P14854 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1047480|uniprotkb:Q6IBL4|uniprotkb:B2R5C9|ensembl:ENSP00000376037|ensembl:ENSP00000466818|ensembl:ENSP00000497926 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:cx6b1_human(display_long)|uniprotkb:COX6B1(gene name)|psi-mi:COX6B1(display_short)|uniprotkb:COX6B(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIb isoform 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001854.1|ensembl:ENSG00000126267(gene)|ensembl:ENST00000392201(transcript)|ensembl:ENST00000592141(transcript)|ensembl:ENST00000649813(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0021762"(substantia nigra development)|go:"GO:0045277"(respiratory chain complex IV)|interpro:IPR003213(Cytochrome c oxidase, subunit VIb)|interpro:IPR036549|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:YuBPGRO9+EC9fWz+mWALa2DyZL89606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O75306 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9BU61 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9UDW1 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1224495|uniprotkb:B5MCM5|uniprotkb:Q9T2V6|ensembl:ENSP00000332887 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:qcr9_human(display_long)|uniprotkb:UQCR10(gene name)|psi-mi:UQCR10(display_short)|uniprotkb:HSPC119(orf name)|uniprotkb:UCRC(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 7.2 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 7 kDa protein(gene name synonym)|uniprotkb:Complex III subunit X(gene name synonym)|uniprotkb:Complex III subunit 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001003684.1|refseq:NP_037519.2|interpro:IPR036656|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|ensembl:ENSG00000184076(gene)|ensembl:ENST00000330029(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR008027(Ubiquinol-cytochrome C reductase, UQCRX/QCR9-like) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:DDANQjwNz4ft+SVqOawiqaxueJk9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O43920 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O95169 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O95139 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1053340|uniprotkb:Q6IB84|ensembl:ENSP00000369176|uniprotkb:A8K0Y7|uniprotkb:Q5VYT2 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndub6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B17 subunit(gene name synonym)|uniprotkb:Complex I-B17(gene name synonym)|uniprotkb:NDUFB6(gene name)|psi-mi:NDUFB6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000165264(gene)|ensembl:ENST00000379847(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR019174|mint:O95139|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_877416.1|refseq:NP_002484.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:topkNBeCU1z26byuWjSujC8PshA9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:O95167 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246131|ensembl:ENSP00000398290|ensembl:ENSP00000418438|ensembl:ENSP00000477783|ensembl:ENSP00000477919|ensembl:ENSP00000478119|ensembl:ENSP00000480437|ensembl:ENSP00000481545|ensembl:ENSP00000482015|ensembl:ENSP00000483002|ensembl:ENSP00000483683|ensembl:ENSP00000483934|ensembl:ENSP00000484436 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndua3_human(display_long)|uniprotkb:NDUFA3(gene name)|psi-mi:NDUFA3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B9 subunit(gene name synonym)|uniprotkb:Complex I-B9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_004533.1|refseq:XP_016882322.1|ensembl:ENSG00000170906(gene)|ensembl:ENSG00000273642(gene)|ensembl:ENSG00000274359(gene)|ensembl:ENSG00000275605(gene)|ensembl:ENSG00000275724(gene)|ensembl:ENSG00000276061(gene)|ensembl:ENSG00000276220(gene)|ensembl:ENSG00000276766(gene)|ensembl:ENSG00000277722(gene)|ensembl:ENSG00000278365(gene)|ensembl:ENST00000419113(transcript)|ensembl:ENST00000485876(transcript)|ensembl:ENST00000610406(transcript)|ensembl:ENST00000612327(transcript)|ensembl:ENST00000617282(transcript)|ensembl:ENST00000618338(transcript)|ensembl:ENST00000619253(transcript)|ensembl:ENST00000619966(transcript)|ensembl:ENST00000620289(transcript)|ensembl:ENST00000621307(transcript)|ensembl:ENST00000622523(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR026626|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENST00000613276(transcript) - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:12DLltKnKM9F+jax3k6NKJu+suQ9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P03905 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P51970 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1237250|uniprotkb:B1AM93|uniprotkb:Q9Y6N0|ensembl:ENSP00000362873 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ndua8_human(display_long)|uniprotkb:NDUFA8(gene name)|psi-mi:NDUFA8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_055037.1|ensembl:ENSG00000119421(gene)|ensembl:ENST00000373768(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:P51970|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:buGk0RR4rNyaFDdsjenBqzYzlMs9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9NZJ7 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-297455|ensembl:ENSP00000362730|uniprotkb:Q6PK60|uniprotkb:Q6UX45|uniprotkb:Q7L465|uniprotkb:Q9BW23|uniprotkb:Q9NZR6|uniprotkb:Q9UJZ5|uniprotkb:B2RCE3|uniprotkb:A8KAX5 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:mtch1_human(display_long)|uniprotkb:Presenilin-associated protein(gene name synonym)|uniprotkb:CGI-64(orf name)|uniprotkb:MTCH1(gene name)|psi-mi:MTCH1(display_short)|uniprotkb:PSAP(gene name synonym)|uniprotkb:UNQ1871/PRO4314(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000137409(gene)|ensembl:ENST00000373627(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045161"(neuronal ion channel clustering)|interpro:IPR018108|interpro:IPR023395|mint:Q9NZJ7|refseq:NP_055156.1|refseq:NP_001258570.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:I0J5CxSiLB4OS6mhqwygLq389xY9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P10606 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_001853.2|ensembl:ENSG00000135940(gene)|ensembl:ENST00000258424(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9BUR5 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-10763408|uniprotkb:B2R4K9|uniprotkb:Q9H3J9|ensembl:ENSP00000368528 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:mic26_human(display_long)|uniprotkb:Protein FAM121B(gene name synonym)|uniprotkb:My025(orf name)|uniprotkb:UNQ1866/PRO4302(orf name)|uniprotkb:Apolipoprotein O(gene name synonym)|uniprotkb:MIC23(gene name synonym)|uniprotkb:MIC26(gene name synonym)|uniprotkb:MICOS complex subunit MIC23(gene name synonym)|uniprotkb:APOO(gene name)|psi-mi:APOO(display_short)|uniprotkb:FAM121B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_077027.1|ensembl:ENSG00000184831(gene)|ensembl:ENST00000379226(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001401"(SAM complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR019166|interpro:IPR033182|reactome:R-HSA-8949613|refseq:XP_016885326.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:xu+C1gnPf3M63LJIPv1R57L62lc9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9Y512 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-748409|uniprotkb:Q969Y9|uniprotkb:Q96I46|uniprotkb:Q9NW85|uniprotkb:Q9UQM9|ensembl:ENSP00000345445|uniprotkb:Q53HC4|uniprotkb:Q56VW7 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:sam50_human(display_long)|uniprotkb:SAMM50(gene name)|psi-mi:SAMM50(display_short)|uniprotkb:CGI-51(orf name)|uniprotkb:Transformation-related gene 3 protein(gene name synonym)|uniprotkb:TRG3(orf name)|uniprotkb:SAM50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000100347(gene)|refseq:NP_056195.3|ensembl:ENST00000350028(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q9Y512|rcsb pdb:6YOO|rcsb pdb:6YOP|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:wpqEL4ia/LUNdXSlQBRZxPfwCcY9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9P032 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9P0J0 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:P03886 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9Y375 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPL8 uniprotkb:Q9BQ95 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guarani et al. (2014) pubmed:24344204|imex:IM-24050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-10763405|imex:IM-24050-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:f1a f1b f1d st2 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells) - 2015/03/31 2015/04/07 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:HHxGK8g70l8pqNgbSGFXANYMLuw false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)