#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13569	uniprotkb:Q7Z333	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093976|imex:IM-23802-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:2A77583840430AC7|rigid:TezrHQGoMPrwmN/XSilwSHqIMTA	false	sufficient binding region:74-410	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z333	uniprotkb:Q9NS56	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-1996473|uniprotkb:O43273|uniprotkb:Q6P987|uniprotkb:Q9NS55|uniprotkb:Q9UNR9|ensembl:ENSP00000353735	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:toprs_human(display_long)|uniprotkb:TOPORS(gene name)|psi-mi:TOPORS(display_short)|uniprotkb:LUN(gene name synonym)|uniprotkb:TP53BPL(gene name synonym)|uniprotkb:SUMO1-protein E3 ligase Topors(gene name synonym)|uniprotkb:Topoisomerase I-binding RING finger protein(gene name synonym)|uniprotkb:Topoisomerase I-binding arginine/serine-rich protein(gene name synonym)|uniprotkb:Tumor suppressor p53-binding protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Topors(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093996|imex:IM-23802-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_001182551.1|refseq:NP_005793.2|ensembl:ENSG00000197579(gene)|ensembl:ENST00000360538(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005814"(centriole)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010842"(retina layer formation)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030496"(midbody)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046872"(metal ion binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q9NS56|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4755510	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:8KlxsG2SOxo/Li/zMRdUsXbhNlg9606	intact-crc:E417E57B9B22E5E8|rigid:M+cGnsmVbBgInMa2LhVPKk40f/A	false	sufficient binding region:1-650	sufficient binding region:468-1045	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06265	uniprotkb:Q7Z333	intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093994|imex:IM-23802-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:9C9080363BFB212B|rigid:Eom5Vb8R+bVFf4KCIgHh9yiLUGM	false	sufficient binding region:158-439	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UBT2	uniprotkb:Q7Z333	intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093992|imex:IM-23802-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1 and 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:0897661AC6D6CB82|rigid:zt++XgBIFIEckZfXosWFs2j8VwU	false	sufficient binding region:451-640	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z333	uniprotkb:Q7Z333	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093990|imex:IM-23802-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1 and 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:2459AFE0DA2E46D7|rigid:wHgC/0oG9RNGChz8kZOUDuF/jfQ	false	sufficient binding region:1-668	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z333	uniprotkb:P63279	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093986|imex:IM-23802-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:A6CD4E0299509B3E|rigid:sT01KWhZx6uua+T/QDFfhygNBi4	false	sufficient binding region:1-650	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75925	uniprotkb:Q7Z333	intact:EBI-629434|uniprotkb:Q147X4|uniprotkb:Q99751|uniprotkb:Q9UN02|uniprotkb:B2RB67|uniprotkb:B3KSY9|ensembl:ENSP00000249636|intact:EBI-28970067|uniprotkb:C5J4B4	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:pias1_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:Gu-binding protein(gene name synonym)|uniprotkb:RNA helicase II-binding protein(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:PIAS1(gene name)|psi-mi:PIAS1(display_short)|uniprotkb:DDXBP1(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS1(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093980|imex:IM-23802-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001307616.1|refseq:NP_057250.1|ensembl:ENSP00000249636|ensembl:ENST00000545237|ensembl:ENSP00000438574|ensembl:ENSG00000033800(gene)|ensembl:ENST00000249636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O75925|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1V66|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-5696395|reactome:R-HSA-877312|refseq:XP_016878177.1|dip:DIP-5970N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:SJB9TG4K6p8GSZwh0MNanj6cGt49606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:D75EA994F3CDD386|rigid:xSw6oor+G4q0qWaRHSw5ENxBKmg	false	sufficient binding region:318-651	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z333	uniprotkb:Q12873	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093978|imex:IM-23802-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:UjefFUXiV28qhOP9BoIUansxl+k9606	intact-crc:4E6953E3C4A66F43|rigid:sif43L6GKWj+plUqXpwII9MGe4Q	false	sufficient binding region:1-650	sufficient binding region:1818-1967	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-10094081	uniprotkb:Q7Z333	-	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:bcyrn1_rc-human(display_short)|psi-mi:EBI-10094081(display_long)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10094110|imex:IM-23802-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	omim:602433(see-also)	comment:"prey clone found to be a fusion of KIF1B (intron 5, exons 6-9 and approx. 1.4 kb of intron 9) and BCYRN1 in reverse complement direction raltive to the Gal4 activation domain with a stop codon immediately prior to the KIF1B cDNA sequence"	-	figure legend:table 1 and 1A and B|comment:"wildtype SETX and trp305cys mutant (variant in in SCAR1 [MIM:606002]) do not interact"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:jAZthf1frZVyC42jACfIFt0UZWg9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:8739E110363C9E50|rigid:22sKL419UcdLevK355JaWGgyBp8	false	-	sufficient binding region:1-650|mutation:389-389	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z333	uniprotkb:P0CG48	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093984|imex:IM-23802-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3	-	-	-	figure legend:table 1 and 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	intact-crc:A44E34F03B99717E|rigid:fIthBiITYEpM0p2nVlyhCErMx2A	false	sufficient binding region:1-650	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63165	uniprotkb:Q7Z333	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093988|imex:IM-23802-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1 and 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:E90F3B0ACD64502B|rigid:n/yiMD/ze4Cwbw5v6gm9S+UKdIw	false	-	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H2X6	uniprotkb:Q7Z333	intact:EBI-348345|ensembl:ENSP00000385571|uniprotkb:Q75MR7|uniprotkb:Q8WWI4|uniprotkb:Q9H2Y1	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:hipk2_human(display_long)|uniprotkb:HIPK2(gene name)|psi-mi:HIPK2(display_short)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093982|imex:IM-23802-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030578"(PML body organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|rcsb pdb:6P5S|rcsb pdb:7NCF|reactome:R-HSA-2032785|reactome:R-HSA-3899300|reactome:R-HSA-5578768|reactome:R-HSA-6804756|reactome:R-HSA-8939243|reactome:R-HSA-9022692|mint:Q9H2X6|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|ensembl:ENSG00000064393(gene)|ensembl:ENST00000406875(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0001654"(eye development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001106710.1|refseq:NP_073577.3|ensembl:ENSP00000385571|ensembl:ENST00000428878|ensembl:ENSP00000413724|dip:DIP-31716N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:jCklf83jA3PA1CGAimi3q9E9CW49606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:C7A9000D0126C5E2|rigid:l7kkpJ4vrX6a055JkvCSQxrBwS8	false	sufficient binding region:216-527	sufficient binding region:1-650	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06265	uniprotkb:Q7Z333	intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093923|imex:IM-23802-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:040D17C6A1B82F58|rigid:Eom5Vb8R+bVFf4KCIgHh9yiLUGM	false	sufficient binding region:158-439	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75925	uniprotkb:Q7Z333	intact:EBI-629434|uniprotkb:Q147X4|uniprotkb:Q99751|uniprotkb:Q9UN02|uniprotkb:B2RB67|uniprotkb:B3KSY9|ensembl:ENSP00000249636|intact:EBI-28970067|uniprotkb:C5J4B4	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:pias1_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:Gu-binding protein(gene name synonym)|uniprotkb:RNA helicase II-binding protein(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:PIAS1(gene name)|psi-mi:PIAS1(display_short)|uniprotkb:DDXBP1(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS1(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093885|imex:IM-23802-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001307616.1|refseq:NP_057250.1|ensembl:ENSP00000249636|ensembl:ENST00000545237|ensembl:ENSP00000438574|ensembl:ENSG00000033800(gene)|ensembl:ENST00000249636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O75925|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1V66|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-5696395|reactome:R-HSA-877312|refseq:XP_016878177.1|dip:DIP-5970N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:SJB9TG4K6p8GSZwh0MNanj6cGt49606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:9A7F9186BABD5264|rigid:xSw6oor+G4q0qWaRHSw5ENxBKmg	false	sufficient binding region:318-651	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H2X6	uniprotkb:Q7Z333	intact:EBI-348345|ensembl:ENSP00000385571|uniprotkb:Q75MR7|uniprotkb:Q8WWI4|uniprotkb:Q9H2Y1	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:hipk2_human(display_long)|uniprotkb:HIPK2(gene name)|psi-mi:HIPK2(display_short)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093955|imex:IM-23802-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030578"(PML body organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|rcsb pdb:6P5S|rcsb pdb:7NCF|reactome:R-HSA-2032785|reactome:R-HSA-3899300|reactome:R-HSA-5578768|reactome:R-HSA-6804756|reactome:R-HSA-8939243|reactome:R-HSA-9022692|mint:Q9H2X6|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|ensembl:ENSG00000064393(gene)|ensembl:ENST00000406875(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0001654"(eye development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001106710.1|refseq:NP_073577.3|ensembl:ENSP00000385571|ensembl:ENST00000428878|ensembl:ENSP00000413724|dip:DIP-31716N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:jCklf83jA3PA1CGAimi3q9E9CW49606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:B252BAE2C3FC0521|rigid:l7kkpJ4vrX6a055JkvCSQxrBwS8	false	sufficient binding region:216-527	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS56	uniprotkb:Q7Z333	intact:EBI-1996473|uniprotkb:O43273|uniprotkb:Q6P987|uniprotkb:Q9NS55|uniprotkb:Q9UNR9|ensembl:ENSP00000353735	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:toprs_human(display_long)|uniprotkb:TOPORS(gene name)|psi-mi:TOPORS(display_short)|uniprotkb:LUN(gene name synonym)|uniprotkb:TP53BPL(gene name synonym)|uniprotkb:SUMO1-protein E3 ligase Topors(gene name synonym)|uniprotkb:Topoisomerase I-binding RING finger protein(gene name synonym)|uniprotkb:Topoisomerase I-binding arginine/serine-rich protein(gene name synonym)|uniprotkb:Tumor suppressor p53-binding protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Topors(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093947|imex:IM-23802-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001182551.1|refseq:NP_005793.2|ensembl:ENSG00000197579(gene)|ensembl:ENST00000360538(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005814"(centriole)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010842"(retina layer formation)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030496"(midbody)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046872"(metal ion binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q9NS56|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4755510	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:8KlxsG2SOxo/Li/zMRdUsXbhNlg9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:5EEBD2B58B6F4017|rigid:M+cGnsmVbBgInMa2LhVPKk40f/A	false	sufficient binding region:468-1045	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13569	uniprotkb:Q7Z333	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093931|imex:IM-23802-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:9C972464F364F9C5|rigid:TezrHQGoMPrwmN/XSilwSHqIMTA	false	sufficient binding region:74-410	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z333	uniprotkb:P63279	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093877|imex:IM-23802-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:13ECB10D5F28070E|rigid:sT01KWhZx6uua+T/QDFfhygNBi4	false	sufficient binding region:1-650	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBT2	uniprotkb:Q7Z333	intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093869|imex:IM-23802-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:7EAA3C7F40BB835F|rigid:zt++XgBIFIEckZfXosWFs2j8VwU	false	sufficient binding region:451-640	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z333	uniprotkb:Q7Z333	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093820|imex:IM-23802-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:8D92F6ADCED10AF6|rigid:wHgC/0oG9RNGChz8kZOUDuF/jfQ	false	sufficient binding region:1-668	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-10094081	uniprotkb:Q7Z333	-	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:bcyrn1_rc-human(display_short)|psi-mi:EBI-10094081(display_long)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10094083|imex:IM-23802-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	omim:602433(see-also)	comment:"prey clone found to be a fusion of KIF1B (intron 5, exons 6-9 and approx. 1.4 kb of intron 9) and BCYRN1 in reverse complement direction raltive to the Gal4 activation domain with a stop codon immediately prior to the KIF1B cDNA sequence"	-	figure legend:table 1|comment:"wildtype SETX and trp305cys mutant (variant in in SCAR1 [MIM:606002]) do not interact"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:jAZthf1frZVyC42jACfIFt0UZWg9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:469AE68423A4BA13|rigid:22sKL419UcdLevK355JaWGgyBp8	false	-	sufficient binding region:1-650|mutation:389-389	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63165	uniprotkb:Q7Z333	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093917|imex:IM-23802-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:82B8C02EEB30CDC3|rigid:n/yiMD/ze4Cwbw5v6gm9S+UKdIw	false	-	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CG48	uniprotkb:Q7Z333	intact:EBI-3390054|ensembl:ENSP00000344818|ensembl:ENSP00000441543|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093963|imex:IM-23802-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5656121|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9613829|ensembl:ENSG00000150991(gene)|ensembl:ENST00000339647(transcript)|ensembl:ENST00000536769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:1ZO6|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|interpro:IPR000626(Ubiquitin)|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2MI8|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3PTF|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6EQI|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|refseq:NP_066289.3	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/22	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:37C194B7747DC519|rigid:fIthBiITYEpM0p2nVlyhCErMx2A	false	-	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12873	uniprotkb:Q7Z333	intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10093939|imex:IM-23802-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/01/22	2015/01/30	rogid:UjefFUXiV28qhOP9BoIUansxl+k9606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:E3A0281F6FFB9AF2|rigid:sif43L6GKWj+plUqXpwII9MGe4Q	false	sufficient binding region:1818-1967	sufficient binding region:1-650	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z333	uniprotkb:Q7Z333	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10094143|imex:IM-23802-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/22	2015/01/22	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:46D3F8BCE502D296|rigid:jlOPruAgIGlrVJ1qVPONkkYxl88	false	sufficient binding region:1-600	sufficient binding region:1-600	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q7Z333	uniprotkb:Q7Z333	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10094160|imex:IM-23802-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	-	-	-	figure legend:2C|comment:multimers have been detetcted|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2015/01/22	2015/01/30	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	intact-crc:C80B583F92D9FA2D|rigid:wHgC/0oG9RNGChz8kZOUDuF/jfQ	false	flag tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z333	uniprotkb:Q8N769	intact:EBI-1220123|uniprotkb:A2A396|uniprotkb:Q5JUJ1|uniprotkb:O75120|uniprotkb:Q3KQX4|uniprotkb:Q68DW5|uniprotkb:Q6AZD7|uniprotkb:Q7Z3J6|uniprotkb:Q8WX33|uniprotkb:Q9H9D1|uniprotkb:Q9NVP9|uniprotkb:B2RPB2|uniprotkb:B5ME16|uniprotkb:C9JQ10|ensembl:ENSP00000224140	intact:EBI-10094395|uniprotkb:Q2HIX2|uniprotkb:Q3KNR7	psi-mi:setx_human(display_long)|uniprotkb:SETX(gene name)|psi-mi:SETX(display_short)|uniprotkb:ALS4(gene name synonym)|uniprotkb:KIAA0625(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:SEN1 homolog(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 4 protein(gene name synonym)|uniprotkb:Senataxin(gene name synonym)	psi-mi:cn178_human(display_long)|uniprotkb:C14orf178(gene name)|psi-mi:C14orf178(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bennett et al. (2013)	imex:IM-23802|pubmed:24244371	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10094393|imex:IM-23802-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055861.3|refseq:XP_011516706.1|refseq:XP_011516707.1|refseq:XP_016869984.1|refseq:XP_005272228.1|refseq:XP_005272229.1|refseq:XP_005272230.1|dip:DIP-38360N|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060566"(positive regulation of DNA-templated transcription, termination)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000806"("positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|ensembl:ENSG00000107290(gene)|ensembl:ENST00000224140(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006396"(RNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|refseq:XP_016869986.1	refseq:NP_001167449.1|refseq:NP_777603.1	omim:602433(see-also)	-	-	figure legend:6|comment:wildtype STX does not interact|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/01/22	2015/01/22	rogid:Dc7CRsHfS4kFhGJhPv9mLYieKC09606	rogid:iRUI0eTqpg8ASTWBWN50/vHy0ro9606	intact-crc:40B5D481550616E4|rigid:f+zCfzQE9AuaY7LKPnsMiJs29oU	false	sufficient binding region:1-650|flag tag:?-?|mutation:389-389	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)