#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:B5DFK6	uniprotkb:D3ZVH6	intact:EBI-8097016|intact:MINT-8043876|ensembl:ENSRNOP00000025878	intact:EBI-10899963|ensembl:ENSRNOP00000063448	psi-mi:b5dfk6_rat(display_long)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:rCG_29405(orf name)	psi-mi:d3zvh6_rat(display_long)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short)	psi-mi:"MI:0096"(pull down)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10903770|imex:IM-24480-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1308659|refseq:NP_001094189.1|ensembl:ENSRNOG00000018977(gene)|ensembl:ENSRNOT00000025878(transcript)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)	rgd:1560511|ensembl:ENSRNOG00000012940(gene)|ensembl:ENSRNOT00000067636(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	-	comment:mint	-	figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/16	2015/07/28	rogid:WbiOMPxeS/2bjeVBzmOb+/uegSc10116	rogid:gkRI6ZoBHn3b28i9VmXeCMj1Ps810116	rigid:P5VrUkIBNIyP7cPyRYBbn/Unedc	false	glutathione s tranferase tag:?-?|sufficient binding region:650-720	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:B5DFK6	uniprotkb:D3ZVH6	intact:EBI-8097016|intact:MINT-8043876|ensembl:ENSRNOP00000025878	intact:EBI-10899963|ensembl:ENSRNOP00000063448	psi-mi:b5dfk6_rat(display_long)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:rCG_29405(orf name)	psi-mi:d3zvh6_rat(display_long)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short)	psi-mi:"MI:0096"(pull down)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10903802|imex:IM-24480-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1308659|refseq:NP_001094189.1|ensembl:ENSRNOG00000018977(gene)|ensembl:ENSRNOT00000025878(transcript)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)	rgd:1560511|ensembl:ENSRNOG00000012940(gene)|ensembl:ENSRNOT00000067636(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	-	comment:mint	-	figure legend:3E and F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/16	2015/07/28	rogid:WbiOMPxeS/2bjeVBzmOb+/uegSc10116	rogid:gkRI6ZoBHn3b28i9VmXeCMj1Ps810116	rigid:P5VrUkIBNIyP7cPyRYBbn/Unedc	false	sufficient binding region:720-1204|glutathione s tranferase tag:?-?	necessary binding region:1-36|ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:D3ZVH6	uniprotkb:A0A0G2JWD6	intact:EBI-10899963|ensembl:ENSRNOP00000063448	intact:EBI-10961259|ensembl:ENSRNOP00000069838	psi-mi:d3zvh6_rat(display_long)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short)	psi-mi:a0a0g2jwd6_rat(display_long)|uniprotkb:Ap3b1(gene name)|psi-mi:Ap3b1(display_short)|uniprotkb:Ap3b1_predicted(gene name synonym)|uniprotkb:rCG_44802(orf name)	psi-mi:"MI:0096"(pull down)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10903866|imex:IM-24480-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1560511|ensembl:ENSRNOG00000012940(gene)|ensembl:ENSRNOT00000067636(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	refseq:XP_006231876.1|rgd:1310256|ensembl:ENSRNOG00000010624(gene)|ensembl:ENSRNOT00000089599(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007040"(lysosome organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030324"(lung development)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032438"(melanosome organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043473"(pigmentation)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0098773"(skin epidermis development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|reactome:R-RNO-432722	-	-	-	figure legend:3D|comment:"The association Vps41:Ap2b1 is much weaker than Vps41:Ap3d1"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/16	2015/08/13	rogid:gkRI6ZoBHn3b28i9VmXeCMj1Ps810116	rogid:QMZCno2S8gKVdjaKMniRZAA+hC010116	rigid:WKv5Z50hPC3qjFo8C6pYXotM91E	false	ha tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:643..643-1094	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:D4AE00	uniprotkb:D3ZVH6	intact:EBI-10961388|ensembl:ENSRNOP00000026030	intact:EBI-10899963|ensembl:ENSRNOP00000063448	psi-mi:d4ae00_rat(display_long)|uniprotkb:Ap3b2(gene name)|psi-mi:Ap3b2(display_short)	psi-mi:d3zvh6_rat(display_long)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short)	psi-mi:"MI:0096"(pull down)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10961382|imex:IM-24480-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1308950|refseq:XP_003748939.1|refseq:XP_003753350.1|ensembl:ENSRNOG00000019249(gene)|ensembl:ENSRNOT00000026030(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390	rgd:1560511|ensembl:ENSRNOG00000012940(gene)|ensembl:ENSRNOT00000067636(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	-	-	-	figure legend:3D|comment:"The association Vps41:Ap2b2 is much weaker than Vps41:Ap3d1"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/16	2015/08/13	rogid:FPtXkHHhp9raxDXxCcEccH8wMOw10116	rogid:gkRI6ZoBHn3b28i9VmXeCMj1Ps810116	rigid:EN4tdtBMvPIILlsNU6EGV/FXIr0	false	glutathione s tranferase tag:?-?|sufficient binding region:633-1082	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:D3ZVH6	uniprotkb:D3ZVH6	intact:EBI-10899963|ensembl:ENSRNOP00000063448	intact:EBI-10899963|ensembl:ENSRNOP00000063448	psi-mi:d3zvh6_rat(display_long)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short)	psi-mi:d3zvh6_rat(display_long)|uniprotkb:Vps41(gene name)|psi-mi:Vps41(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10903906|imex:IM-24480-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1560511|ensembl:ENSRNOG00000012940(gene)|ensembl:ENSRNOT00000067636(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	rgd:1560511|ensembl:ENSRNOG00000012940(gene)|ensembl:ENSRNOT00000067636(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0071439"(clathrin complex)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	-	-	-	figure legend:5G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2015/07/16	2015/07/28	rogid:gkRI6ZoBHn3b28i9VmXeCMj1Ps810116	rogid:gkRI6ZoBHn3b28i9VmXeCMj1Ps810116	rigid:8oRqp5y5HR6/UosZeZNtQJEw6BE	false	ha tag:?-?	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P49754	uniprotkb:P49754	intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457	intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457	psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym)	psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10903937|imex:IM-24480-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055211.2|refseq:NP_542198.2|ensembl:ENSG00000006715(gene)|ensembl:ENST00000310301(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	refseq:NP_055211.2|refseq:NP_542198.2|ensembl:ENSG00000006715(gene)|ensembl:ENST00000310301(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	-	-	-	figure legend:5E|comment:Assembles into a lattic at pH 6.5 but not pH 7.9.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/16	2015/07/22	rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606	rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606	rigid:wzZzD13ecclvxWBtQqW4LTYTYro	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49754	uniprotkb:P49754	intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457	intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457	psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym)	psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Asensio et al. (2013)	pubmed:24210660|imex:IM-24480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10903966|imex:IM-24480-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055211.2|refseq:NP_542198.2|ensembl:ENSG00000006715(gene)|ensembl:ENST00000310301(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	refseq:NP_055211.2|refseq:NP_542198.2|ensembl:ENSG00000006715(gene)|ensembl:ENST00000310301(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	-	-	-	figure legend:5B, C and D, S3|comment:Self-association is inhibited by increasing salt concentration|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/16	2015/07/22	rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606	rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606	rigid:wzZzD13ecclvxWBtQqW4LTYTYro	false	necessary binding region:595-854	necessary binding region:595-854	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)