#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y2Z0 uniprotkb:A0A0H3NF38 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10689858|imex:IM-26065-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:1A, 1E and suppl fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A false - sufficient binding region:171-479|necessary binding region:430-479|ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A0A0H3NF38 uniprotkb:Q9Y2Z0 intact:EBI-10689860|ensemblbacteria:CBW18313 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10766573|imex:IM-26065-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N - - - figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and SGT1 identified|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA false ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A0A0H3NF38 uniprotkb:Q9Y239 intact:EBI-10689860|ensemblbacteria:CBW18313 intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823 psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10766573|imex:IM-26065-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_006083.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|refseq:XP_005249625.1|refseq:XP_005249629.1|ensembl:ENSG00000106100(gene)|ensembl:ENST00000222823(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001315(Caspase Recruitment)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR032675|interpro:IPR041075|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR041267|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|go:"GO:1904417"(positive regulation of xenophagy)|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:XP_006715696.1|dip:DIP-41064N - - - figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and SGT1 identified|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606 rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y239 uniprotkb:A0A0H3NF38 intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10768084|imex:IM-26065-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006083.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|refseq:XP_005249625.1|refseq:XP_005249629.1|ensembl:ENSG00000106100(gene)|ensembl:ENST00000222823(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001315(Caspase Recruitment)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR032675|interpro:IPR041075|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR041267|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|go:"GO:1904417"(positive regulation of xenophagy)|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:XP_006715696.1|dip:DIP-41064N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and SGT1 identified|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y239 uniprotkb:Q9Y2Z0 intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym) psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10768084|imex:IM-26065-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006083.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|refseq:XP_005249625.1|refseq:XP_005249629.1|ensembl:ENSG00000106100(gene)|ensembl:ENST00000222823(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001315(Caspase Recruitment)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR032675|interpro:IPR041075|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR041267|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|go:"GO:1904417"(positive regulation of xenophagy)|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:XP_006715696.1|dip:DIP-41064N reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N - - - figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and SGT1 identified|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y2Z0 uniprotkb:A0A0H3NF38 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0416"(fluorescence microscopy) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-10689882|imex:IM-26065-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/11 2015/04/26 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A false - flag tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9SUR9 uniprotkb:A0A0H3NF38 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10689897|imex:IM-26065-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/03/12 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:L5zfUjA8+sGvh6mJfootFNhRmKM false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9SUR9 uniprotkb:A0A0H3NF38 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10689908|imex:IM-26065-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:1C and S4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/03/12 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:L5zfUjA8+sGvh6mJfootFNhRmKM false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9SUT5 uniprotkb:A0A0H3NF38 intact:EBI-1581364|ensemblplants:AT4G11260.1 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1b_arath(display_long)|uniprotkb:SGT1B(gene name)|psi-mi:SGT1B(display_short)|uniprotkb:EDM1(gene name synonym)|uniprotkb:ETA3(gene name synonym)|uniprotkb:At4g11260(locus name)|uniprotkb:RPR1(gene name synonym)|uniprotkb:Protein ENHANCED DOWNY MILDEW 1(gene name synonym)|uniprotkb:Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog B(gene name synonym)|uniprotkb:F8L21.50(orf name) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10689916|imex:IM-26065-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_192865.1|ensemblplants:AT4G11260(gene)|ensemblplants:AT4G11260.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009867"(jasmonic acid mediated signaling pathway)|go:"GO:0010187"(negative regulation of seed germination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:1900150"(regulation of defense response to fungus)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|dip:DIP-41227N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:S4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/03/12 rogid:jAA7AimUuQNCH0NJZQDBUFRYpW43702 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:6PcPnwfBBExkC7ev88tLTPvNHWU false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9SUT5 uniprotkb:A0A0H3NF38 intact:EBI-1581364|ensemblplants:AT4G11260.1 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1b_arath(display_long)|uniprotkb:SGT1B(gene name)|psi-mi:SGT1B(display_short)|uniprotkb:EDM1(gene name synonym)|uniprotkb:ETA3(gene name synonym)|uniprotkb:At4g11260(locus name)|uniprotkb:RPR1(gene name synonym)|uniprotkb:Protein ENHANCED DOWNY MILDEW 1(gene name synonym)|uniprotkb:Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog B(gene name synonym)|uniprotkb:F8L21.50(orf name) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10689924|imex:IM-26065-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_192865.1|ensemblplants:AT4G11260(gene)|ensemblplants:AT4G11260.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009867"(jasmonic acid mediated signaling pathway)|go:"GO:0010187"(negative regulation of seed germination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:1900150"(regulation of defense response to fungus)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|dip:DIP-41227N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:S4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/03/12 rogid:jAA7AimUuQNCH0NJZQDBUFRYpW43702 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:6PcPnwfBBExkC7ev88tLTPvNHWU false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y2Z0-2 uniprotkb:A0A0H3NF38 intact:EBI-10768076|ensembl:ENSP00000308067 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10766141|imex:IM-26065-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent) interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:1E and suppl figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:v+sDuQvm0yn7cKswZia+kpy1GZ0 false flag tag:c-c|necessary binding region:260-333|sufficient binding region:111-333 ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y239 uniprotkb:A0A0H3NF38 intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10766584|imex:IM-26065-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006083.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|refseq:XP_005249625.1|refseq:XP_005249629.1|ensembl:ENSG00000106100(gene)|ensembl:ENST00000222823(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001315(Caspase Recruitment)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR032675|interpro:IPR041075|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR041267|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|go:"GO:1904417"(positive regulation of xenophagy)|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:XP_006715696.1|dip:DIP-41064N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/17 rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:Ze1Dipcjt91uMwa/d1UemZLgG38 false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y239 uniprotkb:A0A0H3NF38 intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10766594|imex:IM-26065-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006083.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|refseq:XP_005249625.1|refseq:XP_005249629.1|ensembl:ENSG00000106100(gene)|ensembl:ENST00000222823(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001315(Caspase Recruitment)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR032675|interpro:IPR041075|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR041267|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|go:"GO:1904417"(positive regulation of xenophagy)|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:XP_006715696.1|dip:DIP-41064N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/17 rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:Ze1Dipcjt91uMwa/d1UemZLgG38 false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y2Z0-2 uniprotkb:A0A0H3NF38 intact:EBI-10768076|ensembl:ENSP00000308067 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10768096|imex:IM-26065-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent) interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:suppl figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:v+sDuQvm0yn7cKswZia+kpy1GZ0 false flag tag:c-c ha tag:n-n|sufficient binding region:236-528 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y2Z0 uniprotkb:A0A0H3NF38 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 intact:EBI-10689860|ensemblbacteria:CBW18313 psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Bhavsar et al. (2012) pubmed:23935490|imex:IM-26065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:216597(salts)|taxid:216597("Salmonella typhimurium (strain SL1344)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10766107|imex:IM-26065-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N interpro:IPR032674|interpro:IPR032675|refseq:WP_001115840.1|uniprotkb:E1WC83(uniprot-removed-ac)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|ensemblbacteria:CBW18313(transcript)|ensemblbacteria:SL1344_2217(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016874"(ligase activity)|go:"GO:0030430"(host cell cytoplasm) - - - figure legend:1A and suppl fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/03/11 2015/04/26 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597 rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A false - ha tag:n-n|necessary binding region:430-491 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)