#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H267	uniprotkb:Q9H9C1	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10898946|imex:IM-24741-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1	omim:208085(see-also)	comment:"Following variants/mutations interact: ser243phe (ARC1; UniProt FTId: VAR_057901); asp234his; asp252glu (corresponds to mouse buff phenotype)."	-	figure legend:1B and 2D, 7A-C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/07/08	2015/07/08	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rigid:RjkxD/km/AKGYqXdyAoGcP8pmm0	false	mutation decreasing interaction:30-30|necessary binding region:508-617|mutation decreasing interaction:249-249	necessary binding region:220-425	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H267	uniprotkb:Q9H9C1	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10898954|imex:IM-24741-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1	-	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/07/08	2015/07/08	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rigid:RjkxD/km/AKGYqXdyAoGcP8pmm0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96JC1	uniprotkb:Q91W86	intact:EBI-1050197|uniprotkb:O94869|uniprotkb:Q7Z3V3|uniprotkb:Q96B93|uniprotkb:Q96RM0|uniprotkb:Q71SQ6|ensembl:ENSP00000335193	intact:EBI-2527812|uniprotkb:Q9DBX8|uniprotkb:Q5FWZ1|ensembl:ENSMUSP00000034644	psi-mi:vps39_human(display_long)|uniprotkb:KIAA0770(gene name synonym)|uniprotkb:VPS39(gene name)|psi-mi:VPS39(display_short)|uniprotkb:VAM6(gene name synonym)|uniprotkb:TLP(gene name synonym)|uniprotkb:TRAP1-like protein(gene name synonym)	psi-mi:vps11_mouse(display_long)|uniprotkb:Vps11(gene name)|psi-mi:Vps11(display_short)	psi-mi:"MI:0018"(two hybrid)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10898958|imex:IM-24741-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056104.2|refseq:NP_001288067.1|ensembl:ENSG00000166887(gene)|ensembl:ENST00000348544(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001180(Citron-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|rcsb pdb:6ZE9	ensembl:ENSMUSG00000032127(gene)|ensembl:ENSMUST00000034644(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0005770"(late endosome)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901998"(toxin transport)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|refseq:NP_082165.1	-	-	-	figure legend:1B and C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/07/08	2015/07/08	rogid:BeY8ZDCOyTvZqA0WpdWnmz+giYk9606	rogid:/qYa8VztaqoHnaZ+i2ruGLwSHJQ10090	rigid:G+c2s6aFn+rlwm+/ujKXkUbD6sw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H267	uniprotkb:Q9H9C1	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899097|imex:IM-24741-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1	omim:208085(see-also)	comment:"Following variants/mutations interact: ser243phe (ARC1; UniProt FTId: VAR_057901); asp234his; asp252glu (corresponds to mouse buff phenotype)."	-	figure legend:6B|comment:Bait/prey relationship cannot be established|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/07/08	2015/07/08	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rigid:RjkxD/km/AKGYqXdyAoGcP8pmm0	false	mutation disrupting interaction:235-237|mutation disrupting interaction:232-234|mutation disrupting interaction:251-253	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H267	uniprotkb:O15400	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	psi-mi:"MI:0018"(two hybrid)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899120|imex:IM-24741-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N	-	comment:"Following mutations interact: asp234his, gly249val, leu30pro, ser243phe, asp252glu"	-	figure legend:7A-C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/07/08	2015/07/08	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	rigid:eH8FZy0M4xULEcpAIOMRqkE+evg	false	-	sufficient binding region:165-227(IPR000727)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H9C1	uniprotkb:Q9H267	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899047|imex:IM-24741-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	-	-	comment:"Following mutations interact without significant changes: ser243phe and asp234his"	figure legend:3A-D|comment:The interaction was tested with and without DSP as crosslinking agent, which was supposed to stabilize interactions potentially weakened by Vps33b pathogenic mutations. However the crosslinking agent had no visible effect in the otucome of the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/08	2015/07/08	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rigid:RjkxD/km/AKGYqXdyAoGcP8pmm0	false	-	mutation decreasing interaction:249-249|ha tag:?-?|mutation disrupting interaction:30-30	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49754	uniprotkb:Q9H267	intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym)	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899075|imex:IM-24741-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055211.2|refseq:NP_542198.2|ensembl:ENSG00000006715(gene)|ensembl:ENST00000310301(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	-	-	comment:"Following mutations interact: leu30pro and asp234his"	figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/08	2015/07/08	rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rigid:3uLUgverCM4moJ7/9Fh/G5oKwcs	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R307	uniprotkb:Q9H267	intact:EBI-2527788|uniprotkb:Q8BGV6|uniprotkb:Q8BZX6|uniprotkb:Q8C126|ensembl:ENSMUSP00000036915	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	psi-mi:vps18_mouse(display_long)|uniprotkb:Vps18(gene name)|psi-mi:Vps18(display_short)	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899085|imex:IM-24741-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000034216(gene)|ensembl:ENSMUST00000037280(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|refseq:NP_758473.3	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	-	-	comment:"Following mutations interact: leu30pro and asp234his"	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/08	2015/07/08	rogid:ZYg55QUg3B3pBixwuFUqaAsB+W410090	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rigid:BB435ZZfQUyCHE4HGlCnIjSjx1s	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O15400	uniprotkb:Q9H267	intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899136|imex:IM-24741-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	-	-	comment:"Following mutations show colocalization: leu30pro, asp234his, gly249val"	figure legend:8A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/08	2015/07/08	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rigid:eH8FZy0M4xULEcpAIOMRqkE+evg	false	-	ha tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:Q9H267	uniprotkb:Q9H9C1	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|uniprotkb:B3KQF6|ensembl:ENSP00000327650	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122|ensembl:ENSP00000452181|ensembl:ENSP00000452191	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Tornieri et al. (2013)	imex:IM-24741|pubmed:23918659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10899144|imex:IM-24741-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061138.3|refseq:NP_001276077.1|refseq:XP_011519750.1|refseq:NP_001276078.1|refseq:XP_005254944.1|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|interpro:IPR027121|ensembl:ENSG00000184056(gene)|ensembl:ENST00000333371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033263"(CORVET complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:0070889"(platelet alpha granule organization)|interpro:IPR001619(Sec1-like protein)	refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180246.1|refseq:NP_071350.2|refseq:NP_001180245.1|ensembl:ENSG00000151445(gene)|ensembl:ENST00000343765(transcript)|ensembl:ENST00000553888(transcript)|ensembl:ENST00000557658(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1	-	-	-	figure legend:9A, 10C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/07/08	2015/07/08	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	rigid:RjkxD/km/AKGYqXdyAoGcP8pmm0	false	mutation decreasing interaction:30-30|mutation decreasing interaction:234-234|mutation decreasing interaction:243-243|mutation decreasing interaction:249-249|mutation decreasing interaction:252-252|ha tag:?-?	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0422"(immunostaining)