#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
ensembl:ENSG00000165556	uniprotkb:Q99626	intact:EBI-9253980	intact:EBI-10899513|uniprotkb:O00503|uniprotkb:Q5VTU7|uniprotkb:Q969L8|uniprotkb:Q9UD92|ensembl:ENSP00000370408	psi-mi:cdx2_human_gene(display_short)|psi-mi:ENSG00000165556(display_long)	psi-mi:cdx2_human(display_long)|uniprotkb:CDX2(gene name)|psi-mi:CDX2(display_short)|uniprotkb:CDX3(gene name synonym)|uniprotkb:CDX-3(gene name synonym)|uniprotkb:Caudal-type homeobox protein 2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Coskun et al. (2012)	pubmed:22326557|imex:IM-24349	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10899506|imex:IM-24349-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000165556(gene)|ensembl:ENST00000381020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:5LTY|rcsb pdb:6ES2|rcsb pdb:6ES3|reactome:R-HSA-381771|refseq:NP_001256.3	-	-	-	figure legend:5B|antagonist:"TNF-alpha (P01375)"|causality statement:P01375  decreases binding of  Q99626   to  ENSG00000165556|causality statement:P01375  decreases expression at RNA level of     ENSG00000165556|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma)	-	2015/07/07	2015/07/09	-	rogid:yQHXO+MeoecmYBQNnuOPu9ML8s49606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000112818	uniprotkb:Q99626	intact:EBI-10899582	intact:EBI-10899513|uniprotkb:O00503|uniprotkb:Q5VTU7|uniprotkb:Q969L8|uniprotkb:Q9UD92|ensembl:ENSP00000370408	uniprotkb:MEP1A(gene name)|psi-mi:MEP1A(display_short)|ensembl:mep1a_human_gene(shortlabel)|psi-mi:ENSG00000112818(display_long)	psi-mi:cdx2_human(display_long)|uniprotkb:CDX2(gene name)|psi-mi:CDX2(display_short)|uniprotkb:CDX3(gene name synonym)|uniprotkb:CDX-3(gene name synonym)|uniprotkb:Caudal-type homeobox protein 2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Coskun et al. (2012)	pubmed:22326557|imex:IM-24349	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10899574|imex:IM-24349-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_005579.2	ensembl:ENSG00000165556(gene)|ensembl:ENST00000381020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:5LTY|rcsb pdb:6ES2|rcsb pdb:6ES3|reactome:R-HSA-381771|refseq:NP_001256.3	-	-	-	figure legend:5Bi|antagonist:"TNF-alpha (P01375)"|causality statement:P01375  decreases binding of  Q99626   to  ENSG00000112818|causality statement:Q99626   increases expression at RNA level of   ENSG00000112818|causality statement:P01375  decreases expression at RNA level of     ENSG00000112818|dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma)	-	2015/07/07	2015/07/09	-	rogid:yQHXO+MeoecmYBQNnuOPu9ML8s49606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)