#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ERK7 uniprotkb:P49582 intact:EBI-10769401|uniprotkb:Q8BGP7|ensembl:ENSMUSP00000029562 intact:EBI-10769323|ensembl:ENSMUSP00000032738 psi-mi:achb2_mouse(display_long)|uniprotkb:Chrnb2(gene name)|psi-mi:Chrnb2(display_short) psi-mi:acha7_mouse(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Murray et al. (2012) pubmed:22039094|imex:IM-24133 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10769472|imex:IM-24133-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033732.2|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|ensembl:ENSMUSG00000027950(gene)|ensembl:ENSMUST00000029562(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021562"(vestibulocochlear nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021771"(lateral geniculate nucleus development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042320"(regulation of circadian sleep/wake cycle, REM sleep)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060084"(synaptic transmission involved in micturition)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905144"(response to acetylcholine)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR032932|interpro:IPR036719|interpro:IPR036734|dip:DIP-48730N refseq:NP_031416.3|ensembl:ENSMUSG00000030525(gene)|ensembl:ENSMUST00000032738(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:1905923"(positive regulation of acetylcholine biosynthetic process)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629594|dip:DIP-48732N - - - figure legend:Fig. 1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-SH-EP1)|taxid:9606(human SH-EP1 epithelial-like cell line subcloned from the SK-N-SH neuroblastoma line) - 2015/04/28 2015/04/28 rogid:oeSo9N32iwfTXZjeikOyJsQgo0U10090 rogid:Pvp4ttz6IakmMosoURJI2gFoOcg10090 rigid:7DRFu+jc32fqgmN51luaDGU/btM false mcherry fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q9ERK7 uniprotkb:P49582 intact:EBI-10769401|uniprotkb:Q8BGP7|ensembl:ENSMUSP00000029562 intact:EBI-10769323|ensembl:ENSMUSP00000032738 psi-mi:achb2_mouse(display_long)|uniprotkb:Chrnb2(gene name)|psi-mi:Chrnb2(display_short) psi-mi:acha7_mouse(display_long)|uniprotkb:Chrna7(gene name)|psi-mi:Chrna7(display_short)|uniprotkb:Acra7(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Murray et al. (2012) pubmed:22039094|imex:IM-24133 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-10769681|imex:IM-24133-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033732.2|reactome:R-MMU-629587|reactome:R-MMU-629594|reactome:R-MMU-629597|ensembl:ENSMUSG00000027950(gene)|ensembl:ENSMUST00000029562(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021562"(vestibulocochlear nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021771"(lateral geniculate nucleus development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042320"(regulation of circadian sleep/wake cycle, REM sleep)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060084"(synaptic transmission involved in micturition)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905144"(response to acetylcholine)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR032932|interpro:IPR036719|interpro:IPR036734|dip:DIP-48730N refseq:NP_031416.3|ensembl:ENSMUSG00000030525(gene)|ensembl:ENSMUST00000032738(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001988"(positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure)|go:"GO:0005216"(ion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006811"(ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030673"(axolemma)|go:"GO:0032094"(response to food)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|go:"GO:0050893"(sensory processing)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060112"(generation of ovulation cycle rhythm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099065"(integral component of spine apparatus membrane)|go:"GO:0140059"(dendrite arborization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1905144"(response to acetylcholine)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905920"(positive regulation of CoA-transferase activity)|go:"GO:1905923"(positive regulation of acetylcholine biosynthetic process)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-629594|dip:DIP-48732N - - - figure legend:Fig. 2c, 2d, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-SH-EP1)|taxid:9606(human SH-EP1 epithelial-like cell line subcloned from the SK-N-SH neuroblastoma line) - 2015/04/28 2015/05/07 rogid:oeSo9N32iwfTXZjeikOyJsQgo0U10090 rogid:Pvp4ttz6IakmMosoURJI2gFoOcg10090 rigid:7DRFu+jc32fqgmN51luaDGU/btM false mcherry fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)