#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BUZ4	uniprotkb:Q9E7P0	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-11361108	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0096"(pull down)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11361159|imex:IM-24738-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	-	-	-	figure legend:SF4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/11/05	2015/11/05	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rigid:tw4bcKSPR+/unTxh0B1m2tAQH4M	false	flag tag:?-?	glutathione s tranferase tag:?-?|binding-associated region:1491-1643	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H6S1	uniprotkb:Q9E7P0	intact:EBI-359973|intact:EBI-1384309|uniprotkb:Q86W99|uniprotkb:Q9BQF1|uniprotkb:A8K3M2|ensembl:ENSP00000419371|uniprotkb:C9JB40|uniprotkb:H7BXU6	intact:EBI-11361108	psi-mi:azi2_human(display_long)|uniprotkb:AZI2(gene name)|psi-mi:AZI2(display_short)|uniprotkb:NAP1(gene name synonym)|uniprotkb:TBKBP2(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase-associated protein 1(gene name synonym)|uniprotkb:TILP(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0096"(pull down)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11361169|imex:IM-24738-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127904.1|refseq:NP_001127905.1|refseq:NP_071906.1|ensembl:ENSG00000163512(gene)|ensembl:ENST00000479665(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042110"(T cell activation)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR024581|rcsb pdb:5EP6|rcsb pdb:5Z7G|rcsb pdb:5Z7L|refseq:XP_005265449.1|dip:DIP-27605N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	-	-	-	figure legend:SF4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/11/05	2015/11/05	rogid:lfjd4cD2rm6NOjdh3XTTuFxnK9A9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rigid:ya/4Jv5nGjDzXA1Y9E9xT4Ta9Vs	false	flag tag:?-?	glutathione s tranferase tag:?-?|binding-associated region:1491-1643	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P25963	uniprotkb:Q9E7P0	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	intact:EBI-11361108	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0096"(pull down)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11361179|imex:IM-24738-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	-	-	-	figure legend:SF4|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/11/05	2015/11/05	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rigid:pv06t6YecHuXrvM9onenbxNhvVk	false	flag tag:?-?	glutathione s tranferase tag:?-?|binding-associated region:1491-1643	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P62736	uniprotkb:Q9E7P0	intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784	intact:EBI-11361108	psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422546|imex:IM-24738-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:3D7D3992F814A6DF|rigid:pKzOJUMEHCMrgIdxqMD6FR/l4yc	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:P63261	intact:EBI-11361108	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422562|imex:IM-24738-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:769C5C6CF02C1AE5|rigid:nPFY+tb8Vb2gKf8QZGAvxk3H0mE	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60709	uniprotkb:Q9E7P0	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-11361108	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422554|imex:IM-24738-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:BD4E493DD71A2EEE|rigid:bIQkCMzxyemZXj/nTz2t0stvkOY	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q7Z5R6	intact:EBI-11422591	intact:EBI-2818084|intact:EBI-9091217|uniprotkb:Q8IYL7|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411	psi-mi:polg_alkv(display_long)	psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422597|imex:IM-24738-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_061916.3|refseq:XP_006717514.1|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|ensembl:ENSG00000077420(gene)|ensembl:ENST00000376236(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|ensembl:ENST00000356785|ensembl:ENSP00000349237|ensembl:ENSP00000365411	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606	intact-crc:D3A15282FF94DCD8|rigid:K/J1yKmII/GwjEG/hL8eciyeGac	false	binding-associated region:1509-1661("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P02760	intact:EBI-11422582	intact:EBI-2115136|uniprotkb:P00977|uniprotkb:P02759|uniprotkb:P78491|uniprotkb:Q2TU33|uniprotkb:Q5TBD7|uniprotkb:Q9UC58|uniprotkb:Q9UDI8|ensembl:ENSP00000265132	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:ambp_human(display_long)|uniprotkb:AMBP(gene name)|psi-mi:AMBP(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:ITIL(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422579|imex:IM-24738-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001624.1|ensembl:ENSG00000106927(gene)|ensembl:ENST00000265132(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007565"(female pregnancy)|go:"GO:0009986"(cell surface)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019862"(IgA binding)|go:"GO:0020037"(heme binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046904"(calcium oxalate binding)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR002968(Alpha-1-microglobulin)|interpro:IPR012674(Calycin)|interpro:IPR020901|interpro:IPR022272|interpro:IPR029856|interpro:IPR036880|rcsb pdb:1BIK|rcsb pdb:3QKG|rcsb pdb:4ES7|rcsb pdb:4U30|rcsb pdb:6EJ7|rcsb pdb:6EJ8|rcsb pdb:6EJ9|rcsb pdb:6EJA|rcsb pdb:6EJB|rcsb pdb:6EJC|rcsb pdb:6EJD|reactome:R-HSA-2168880	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:os91tgT4TUMZ1qCf3SRbW5mwlGI9606	intact-crc:0D02BBB692415A32|rigid:6ZYP8lyo0EVNw382ZJVPvTsGcJw	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:P63267	intact:EBI-11361108	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422570|imex:IM-24738-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	intact-crc:63F91B4D8C16239A|rigid:e1FBnFCqCNkQScDiDdB7dFdSe8o	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P42331	intact:EBI-11422640	intact:EBI-9052013|uniprotkb:G5E9G2|uniprotkb:E9PFQ7|uniprotkb:A8K2Y1|uniprotkb:B7Z498|uniprotkb:Q8IXQ2	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rhg25_human(display_long)|uniprotkb:KIAA0053(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 25(gene name synonym)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422637|imex:IM-24738-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1V89|refseq:NP_001007232.2|refseq:NP_001159748.1|refseq:NP_001159749.1|refseq:NP_055697.1|refseq:XP_005264732.1|go:"GO:0001891"(phagocytic cup)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|reactome:R-HSA-9013149	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:k/x1xJsqORENgWWsK1HW+f+WkGM9606	intact-crc:DFE1266CA0AC1BA5|rigid:NQaK815gZTuTftLNs73IJcF/nN4	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q7Z5R6	intact:EBI-11422582	intact:EBI-2818084|intact:EBI-9091217|uniprotkb:Q8IYL7|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422628|imex:IM-24738-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_061916.3|refseq:XP_006717514.1|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|ensembl:ENSG00000077420(gene)|ensembl:ENST00000376236(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|ensembl:ENST00000356785|ensembl:ENSP00000349237|ensembl:ENSP00000365411	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606	intact-crc:3DF63D375A409106|rigid:pfS3dJ2jr2f3PEv4ff7kTDP7nxA	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QXP6	uniprotkb:Q7Z5R6	intact:EBI-11422617	intact:EBI-2818084|intact:EBI-9091217|uniprotkb:Q8IYL7|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411	psi-mi:q8qxp6_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11072(japanese encephalitis virus)|taxid:11072(Japanese encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422614|imex:IM-24738-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	refseq:NP_061916.3|refseq:XP_006717514.1|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|ensembl:ENSG00000077420(gene)|ensembl:ENST00000376236(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|ensembl:ENST00000356785|ensembl:ENSP00000349237|ensembl:ENSP00000365411	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:j+swWwyqabf1+ccBM10YutAzZNg11072	rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606	intact-crc:DD070C5B87F1939A|rigid:eI3cJ+nNKOX9LNxmllVwe5cdaWk	false	binding-associated region:1521-1672("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z5R6	uniprotkb:Q9E7P0	intact:EBI-2818084|intact:EBI-9091217|uniprotkb:Q8IYL7|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411	intact:EBI-11361108	psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422605|imex:IM-24738-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061916.3|refseq:XP_006717514.1|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|ensembl:ENSG00000077420(gene)|ensembl:ENST00000376236(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|ensembl:ENST00000356785|ensembl:ENSP00000349237|ensembl:ENSP00000365411	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:DBE46A723400365C|rigid:vqULHQXjat0Lwx0nV8Qnw6oQEEg	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:O00327	intact:EBI-11422591	intact:EBI-1794206|uniprotkb:O00313|uniprotkb:O00314|uniprotkb:O00315|uniprotkb:O00316|uniprotkb:O00317|uniprotkb:Q99631|uniprotkb:Q99649|uniprotkb:Q8IUT4|uniprotkb:D3DQW6|uniprotkb:A8K645|uniprotkb:B7WPG7|uniprotkb:B5ME11|uniprotkb:Q4G136|uniprotkb:A2I2N6|intact:EBI-28970920|ensembl:ENSP00000384517|ensembl:ENSP00000385581|ensembl:ENSP00000433571	psi-mi:polg_alkv(display_long)	psi-mi:bmal1_human(display_long)|uniprotkb:ARNTL(gene name)|psi-mi:ARNTL(display_short)|uniprotkb:BMAL1(gene name synonym)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Member of PAS protein 3(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP3(gene name synonym)|uniprotkb:bHLH-PAS protein JAP3(gene name synonym)|uniprotkb:BHLHE5(gene name synonym)|uniprotkb:PASD3(gene name synonym)|uniprotkb:PAS domain-containing protein 3(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422682|imex:IM-24738-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENST00000389707|ensembl:ENSP00000374357|ensembl:ENST00000401424|ensembl:ENSP00000385915|ensembl:ENSP00000384517|ensembl:ENST00000403482|ensembl:ENSP00000385897|ensembl:ENSP00000385581|ensembl:ENSP00000433571|refseq:XP_011518414.1|refseq:XP_011518415.1|refseq:NP_001025443.1|refseq:NP_001025444.1|refseq:NP_001169.3|refseq:XP_016873232.1|refseq:NP_001284648.1|refseq:NP_001284651.1|refseq:NP_001284653.1|refseq:XP_016873231.1|refseq:XP_016873235.1|refseq:XP_016873236.1|refseq:XP_016873237.1|dip:DIP-46008N|ensembl:ENSG00000133794(gene)|ensembl:ENST00000403290(transcript)|ensembl:ENST00000403510(transcript)|ensembl:ENST00000529388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4H10|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:UJwUJQAcLUT6aEBNSUZOF6YyvMA9606	intact-crc:58542BD2E240D605|rigid:hSa0lMvYFNdWEP1lOgifV6Ifh0U	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q68CP9	uniprotkb:Q91NH1	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044	intact:EBI-11422668	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422674|imex:IM-24738-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	intact-crc:0F0119E5D0A19CD5|rigid:AEVHdobNc0dynJA8tIR3jWXJqzE	false	-	binding-associated region:2743-3388("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q68CP9	uniprotkb:Q91B85	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044	intact:EBI-11422591	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:polg_alkv(display_long)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422659|imex:IM-24738-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	intact-crc:0D65D2DF1396717B|rigid:85phbNHLqP2iY/AjcGHlTLCv2iY	false	-	binding-associated region:2767-3410("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q68CP9	uniprotkb:Q88489	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044	intact:EBI-11422640	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422651|imex:IM-24738-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	intact-crc:0FCEA39676FF7580|rigid:0TAY/65wQnmrf2HoPrnrBo7GK1M	false	-	binding-associated region:2765-3408("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q9H6S1	intact:EBI-11422582	intact:EBI-359973|intact:EBI-1384309|uniprotkb:Q86W99|uniprotkb:Q9BQF1|uniprotkb:A8K3M2|ensembl:ENSP00000419371|uniprotkb:C9JB40|uniprotkb:H7BXU6	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:azi2_human(display_long)|uniprotkb:AZI2(gene name)|psi-mi:AZI2(display_short)|uniprotkb:NAP1(gene name synonym)|uniprotkb:TBKBP2(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase-associated protein 1(gene name synonym)|uniprotkb:TILP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422725|imex:IM-24738-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001127904.1|refseq:NP_001127905.1|refseq:NP_071906.1|ensembl:ENSG00000163512(gene)|ensembl:ENST00000479665(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042110"(T cell activation)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR024581|rcsb pdb:5EP6|rcsb pdb:5Z7G|rcsb pdb:5Z7L|refseq:XP_005265449.1|dip:DIP-27605N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:lfjd4cD2rm6NOjdh3XTTuFxnK9A9606	intact-crc:6B95ADBD8FACFA5E|rigid:rgipSj8E4LuNRojefOlGU1sbaKs	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H6S1	uniprotkb:Q9E7P0	intact:EBI-359973|intact:EBI-1384309|uniprotkb:Q86W99|uniprotkb:Q9BQF1|uniprotkb:A8K3M2|ensembl:ENSP00000419371|uniprotkb:C9JB40|uniprotkb:H7BXU6	intact:EBI-11361108	psi-mi:azi2_human(display_long)|uniprotkb:AZI2(gene name)|psi-mi:AZI2(display_short)|uniprotkb:NAP1(gene name synonym)|uniprotkb:TBKBP2(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase-associated protein 1(gene name synonym)|uniprotkb:TILP(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422717|imex:IM-24738-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127904.1|refseq:NP_001127905.1|refseq:NP_071906.1|ensembl:ENSG00000163512(gene)|ensembl:ENST00000479665(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042110"(T cell activation)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR024581|rcsb pdb:5EP6|rcsb pdb:5Z7G|rcsb pdb:5Z7L|refseq:XP_005265449.1|dip:DIP-27605N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lfjd4cD2rm6NOjdh3XTTuFxnK9A9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:9ECDF67E3EAA1DA1|rigid:ya/4Jv5nGjDzXA1Y9E9xT4Ta9Vs	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:O15169	intact:EBI-11361108	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422709|imex:IM-24738-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	intact-crc:5159F0AFD3066144|rigid:8ezfJh9CNDj8YYeQhCvvCrfZvFA	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:P54259	intact:EBI-11422701	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076|ensembl:ENSP00000379915	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422698|imex:IM-24738-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001007027.1|refseq:NP_001931.2|ensembl:ENSP00000349076|ensembl:ENSP00000379915|dip:DIP-29423N|ensembl:ENSG00000111676(gene)|ensembl:ENST00000356654(transcript)|ensembl:ENST00000396684(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	crc64:B47603486C672637	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	intact-crc:25C83D252030C6D0|rigid:ZHmF3LE0oesrax1qaNwSvmsefXQ	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:O00327	intact:EBI-11422640	intact:EBI-1794206|uniprotkb:O00313|uniprotkb:O00314|uniprotkb:O00315|uniprotkb:O00316|uniprotkb:O00317|uniprotkb:Q99631|uniprotkb:Q99649|uniprotkb:Q8IUT4|uniprotkb:D3DQW6|uniprotkb:A8K645|uniprotkb:B7WPG7|uniprotkb:B5ME11|uniprotkb:Q4G136|uniprotkb:A2I2N6|intact:EBI-28970920|ensembl:ENSP00000384517|ensembl:ENSP00000385581|ensembl:ENSP00000433571	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:bmal1_human(display_long)|uniprotkb:ARNTL(gene name)|psi-mi:ARNTL(display_short)|uniprotkb:BMAL1(gene name synonym)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Member of PAS protein 3(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP3(gene name synonym)|uniprotkb:bHLH-PAS protein JAP3(gene name synonym)|uniprotkb:BHLHE5(gene name synonym)|uniprotkb:PASD3(gene name synonym)|uniprotkb:PAS domain-containing protein 3(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422690|imex:IM-24738-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENST00000389707|ensembl:ENSP00000374357|ensembl:ENST00000401424|ensembl:ENSP00000385915|ensembl:ENSP00000384517|ensembl:ENST00000403482|ensembl:ENSP00000385897|ensembl:ENSP00000385581|ensembl:ENSP00000433571|refseq:XP_011518414.1|refseq:XP_011518415.1|refseq:NP_001025443.1|refseq:NP_001025444.1|refseq:NP_001169.3|refseq:XP_016873232.1|refseq:NP_001284648.1|refseq:NP_001284651.1|refseq:NP_001284653.1|refseq:XP_016873231.1|refseq:XP_016873235.1|refseq:XP_016873236.1|refseq:XP_016873237.1|dip:DIP-46008N|ensembl:ENSG00000133794(gene)|ensembl:ENST00000403290(transcript)|ensembl:ENST00000403510(transcript)|ensembl:ENST00000529388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4H10|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:UJwUJQAcLUT6aEBNSUZOF6YyvMA9606	intact-crc:5AFF5A9B8729D2FE|rigid:Zc/4q1b4pMp0dsL/VYk5jZetFUI	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BZR8	uniprotkb:Q9E7P0	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-11361108	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422747|imex:IM-24738-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:08AC2AFC8AA05E71|rigid:vlbCrjyhG2YhSOXJSkLP1L5wuds	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5ERI7	uniprotkb:Q9H6S1	intact:EBI-11422733	intact:EBI-359973|intact:EBI-1384309|uniprotkb:Q86W99|uniprotkb:Q9BQF1|uniprotkb:A8K3M2|ensembl:ENSP00000419371|uniprotkb:C9JB40|uniprotkb:H7BXU6	psi-mi:q5eri7_wnv(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:azi2_human(display_long)|uniprotkb:AZI2(gene name)|psi-mi:AZI2(display_short)|uniprotkb:NAP1(gene name synonym)|uniprotkb:TBKBP2(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase-associated protein 1(gene name synonym)|uniprotkb:TILP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11082(wnv)|taxid:11082("West Nile virus (WNV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422739|imex:IM-24738-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	refseq:NP_001127904.1|refseq:NP_001127905.1|refseq:NP_071906.1|ensembl:ENSG00000163512(gene)|ensembl:ENST00000479665(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042110"(T cell activation)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR024581|rcsb pdb:5EP6|rcsb pdb:5Z7G|rcsb pdb:5Z7L|refseq:XP_005265449.1|dip:DIP-27605N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:sncTVhdrW1RxLUewzsHEJmMs6WI11082	rogid:lfjd4cD2rm6NOjdh3XTTuFxnK9A9606	intact-crc:D2089A84FD4CFBCE|rigid:SngU75+HgVb9bEz86SGNwkpiBLs	false	binding-associated region:1522-1673("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JU67	uniprotkb:P14335-PRO_0000037710	intact:EBI-11422790|uniprotkb:A5D8T9|ensembl:ENSP00000362392	intact:EBI-11422582	psi-mi:cf157_human(display_long)|uniprotkb:CFAP157(gene name)|psi-mi:CFAP157(display_short)|uniprotkb:C9orf117(gene name synonym)	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422787|imex:IM-24738-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012520.2|ensembl:ENSG00000160401(gene)|ensembl:ENST00000373295(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR038844	intact:EBI-11462784(chain-parent)	psi-mi:"MI:0471"(mint)	-	chain-seq-start:1506|chain-seq-end:2124	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:+YpnKTVPE0cWosVbmQEmQ9kIVtI9606	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	intact-crc:4FF3B57F7763272E|rigid:VH+kj3u/3t/UPKcNE0xYMPn4c+A	false	-	binding-associated region:1-619("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q8IVT2	intact:EBI-11422591	intact:EBI-2555085|intact:EBI-28972337|ensembl:ENSP00000215582	psi-mi:polg_alkv(display_long)	psi-mi:misp_human(display_long)|uniprotkb:MISP(gene name)|psi-mi:MISP(display_short)|uniprotkb:C19orf21(gene name synonym)|uniprotkb:Mitotic spindle positioning protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422779|imex:IM-24738-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_775752.1|ensembl:ENSP00000215582|refseq:XP_011525987.1|refseq:XP_011525988.1|ensembl:ENSG00000099812(gene)|ensembl:ENST00000215582(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051301"(cell division)|go:"GO:0051640"(organelle localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR029304|interpro:IPR042779	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:HJ0vL2U8LEer8c+rWNdKxkOv2g89606	intact-crc:B48007E2A9F05F3C|rigid:gjfMaKGXYzwBXKzpg+cuL7R5+OQ	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9NWQ4	intact:EBI-11422591	intact:EBI-5666657|uniprotkb:Q9ULR8|uniprotkb:Q9H3M3|uniprotkb:B3KN42|uniprotkb:Q9NWH0|uniprotkb:Q6PEJ7|intact:EBI-28984791|ensembl:ENSP00000261530	psi-mi:polg_alkv(display_long)	psi-mi:gpt2l_human(display_long)|uniprotkb:GPATCH2L(gene name)|psi-mi:GPATCH2L(display_short)|uniprotkb:C14orf118(gene name synonym)|uniprotkb:KIAA1152(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422771|imex:IM-24738-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_060396.2|refseq:NP_060442.2|ensembl:ENSP00000261530|ensembl:ENST00000312858|ensembl:ENSP00000323775|ensembl:ENST00000556663|ensembl:ENSP00000450657|ensembl:ENST00000557263|ensembl:ENSP00000451587|ensembl:ENST00000621494|ensembl:ENSP00000480608|ensembl:ENSG00000089916(gene)|ensembl:ENST00000261530(transcript)|mint:Q9NWQ4	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:d87RToTsMGv1/VCmPi3ivMXaM6k9606	intact-crc:B658EB8F19A5BE60|rigid:2rAJBbMfIgnmH9iS+AWE2NEXmdY	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q96G01	intact:EBI-11422640	intact:EBI-1104509|uniprotkb:O43892|uniprotkb:O43893|uniprotkb:A8K2C3|uniprotkb:F8W113|ensembl:ENSP00000498700	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:bicd1_human(display_long)|uniprotkb:BICD1(gene name)|psi-mi:BICD1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422763|imex:IM-24738-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001003398.1|refseq:NP_001705.2|ensembl:ENSG00000151746(gene)|ensembl:ENST00000652176(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034452"(dynactin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072385"(minus-end-directed organelle transport along microtubule)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1900276"(regulation of proteinase activated receptor activity)|go:"GO:1900737"(negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR018477|mint:Q96G01|reactome:R-HSA-6811436	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:/k7T2ySwKMmpWORAV8jUfsEr+3k9606	intact-crc:045F73494CF0CB6B|rigid:djUxSt0LlgXCX2YfqYZCKWf58kw	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q9BZR8	intact:EBI-11422582	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422755|imex:IM-24738-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	intact-crc:E9EDB09B8262386A|rigid:75I//mGQ/pFay84orjBqsO1uQdw	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q49A88	intact:EBI-11422640	intact:EBI-751035|intact:EBI-2622203|intact:EBI-2858142|uniprotkb:B7Z2T2|uniprotkb:B8ZZ58|intact:EBI-946963|intact:EBI-1104778|uniprotkb:Q7Z3N3|uniprotkb:Q86T30|uniprotkb:Q8WUJ8|uniprotkb:Q96K47|uniprotkb:Q9H9A3|uniprotkb:Q9UFH0|uniprotkb:Q8IWF8|uniprotkb:B8ZZ41|uniprotkb:D3DN98|uniprotkb:B7Z2Q3	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:ccd14_human(display_long)|uniprotkb:CCDC14(gene name)|psi-mi:CCDC14(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422840|imex:IM-24738-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_073594.4|refseq:NP_001295246.1|refseq:XP_005247767.1|refseq:XP_005247768.1|refseq:XP_005247770.1|refseq:XP_005247771.1|refseq:XP_016862545.1|refseq:XP_016862547.1|refseq:XP_016862548.1|mint:Q49A88|dip:DIP-47727N|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0021762"(substantia nigra development)|go:"GO:0034451"(centriolar satellite)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR029343	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:y1bU4io/NA6LIX+pwRkB8gstVuY9606	intact-crc:66617E7B557B8230|rigid:mZ2sIItHQjdLmGY+qaSFXzzuqMc	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:O94983	intact:EBI-11422701	intact:EBI-936534|uniprotkb:Q7Z6M8|uniprotkb:Q8N3V0|uniprotkb:Q8NDG4|uniprotkb:Q96G17|uniprotkb:B9EGL0|uniprotkb:D3DTL5|uniprotkb:E7EWU5|intact:EBI-28966798|ensembl:ENSP00000321813	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:cmta2_human(display_long)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)|uniprotkb:KIAA0909(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422832|imex:IM-24738-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSP00000321813|ensembl:ENST00000361571|ensembl:ENSP00000354828|ensembl:ENST00000381311|ensembl:ENSP00000370712|ensembl:ENST00000414043|ensembl:ENSP00000412886|refseq:NP_001164637.1|refseq:NP_001164638.1|refseq:NP_001164639.1|refseq:NP_055914.2|ensembl:ENSG00000108509(gene)|ensembl:ENST00000348066(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR005559(CG-1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036770|interpro:IPR043661	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:wxiAZcGt9lSBNJVPq38lzfgbIgY9606	intact-crc:F216F298553406DF|rigid:L7xGvxLtSY4wm/KK5WdJa/WBpx8	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QXP6	uniprotkb:O94983	intact:EBI-11422617	intact:EBI-936534|uniprotkb:Q7Z6M8|uniprotkb:Q8N3V0|uniprotkb:Q8NDG4|uniprotkb:Q96G17|uniprotkb:B9EGL0|uniprotkb:D3DTL5|uniprotkb:E7EWU5|intact:EBI-28966798|ensembl:ENSP00000321813	psi-mi:q8qxp6_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:cmta2_human(display_long)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)|uniprotkb:KIAA0909(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11072(japanese encephalitis virus)|taxid:11072(Japanese encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422824|imex:IM-24738-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	ensembl:ENSP00000321813|ensembl:ENST00000361571|ensembl:ENSP00000354828|ensembl:ENST00000381311|ensembl:ENSP00000370712|ensembl:ENST00000414043|ensembl:ENSP00000412886|refseq:NP_001164637.1|refseq:NP_001164638.1|refseq:NP_001164639.1|refseq:NP_055914.2|ensembl:ENSG00000108509(gene)|ensembl:ENST00000348066(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR005559(CG-1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036770|interpro:IPR043661	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:j+swWwyqabf1+ccBM10YutAzZNg11072	rogid:wxiAZcGt9lSBNJVPq38lzfgbIgY9606	intact-crc:C5E7D245D004C6D7|rigid:SnLxX6ssWcR8XWxPbtNf0JrXMY4	false	binding-associated region:1521-1672("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:O94983	intact:EBI-11422591	intact:EBI-936534|uniprotkb:Q7Z6M8|uniprotkb:Q8N3V0|uniprotkb:Q8NDG4|uniprotkb:Q96G17|uniprotkb:B9EGL0|uniprotkb:D3DTL5|uniprotkb:E7EWU5|intact:EBI-28966798|ensembl:ENSP00000321813	psi-mi:polg_alkv(display_long)	psi-mi:cmta2_human(display_long)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)|uniprotkb:KIAA0909(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422816|imex:IM-24738-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSP00000321813|ensembl:ENST00000361571|ensembl:ENSP00000354828|ensembl:ENST00000381311|ensembl:ENSP00000370712|ensembl:ENST00000414043|ensembl:ENSP00000412886|refseq:NP_001164637.1|refseq:NP_001164638.1|refseq:NP_001164639.1|refseq:NP_055914.2|ensembl:ENSG00000108509(gene)|ensembl:ENST00000348066(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR005559(CG-1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036770|interpro:IPR043661	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:wxiAZcGt9lSBNJVPq38lzfgbIgY9606	intact-crc:CB418C9CA8618995|rigid:xlpo3etzKw+ckmMPDw0QZNWWCXw	false	binding-associated region:1509-1661("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94983	uniprotkb:Q9E7P0	intact:EBI-936534|uniprotkb:Q7Z6M8|uniprotkb:Q8N3V0|uniprotkb:Q8NDG4|uniprotkb:Q96G17|uniprotkb:B9EGL0|uniprotkb:D3DTL5|uniprotkb:E7EWU5|intact:EBI-28966798|ensembl:ENSP00000321813	intact:EBI-11361108	psi-mi:cmta2_human(display_long)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)|uniprotkb:KIAA0909(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422808|imex:IM-24738-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000321813|ensembl:ENST00000361571|ensembl:ENSP00000354828|ensembl:ENST00000381311|ensembl:ENSP00000370712|ensembl:ENST00000414043|ensembl:ENSP00000412886|refseq:NP_001164637.1|refseq:NP_001164638.1|refseq:NP_001164639.1|refseq:NP_055914.2|ensembl:ENSG00000108509(gene)|ensembl:ENST00000348066(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR005559(CG-1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR036770|interpro:IPR043661	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:wxiAZcGt9lSBNJVPq38lzfgbIgY9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:C304B46C63F56311|rigid:BZofsevWOn+KnrXSrKfzrY7taKE	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QXP6	uniprotkb:Q13554	intact:EBI-11422617	intact:EBI-1058722|ensembl:ENSP00000379098|uniprotkb:A4D2K1|uniprotkb:A4D2K2|uniprotkb:Q9UGH9|uniprotkb:Q9UNX0|uniprotkb:Q9UNX7|uniprotkb:O95437|uniprotkb:O95438|uniprotkb:Q9UP00|uniprotkb:Q9Y5N4|uniprotkb:Q9Y6F4|uniprotkb:A4D2K0|uniprotkb:O95599|uniprotkb:Q9UGH7|uniprotkb:Q9UGH8|uniprotkb:A4D2K4|uniprotkb:A4D2K6|uniprotkb:A4D2K3|intact:EBI-1383493|uniprotkb:A4D2K5	psi-mi:q8qxp6_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:kcc2b_human(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:CAMK2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11072(japanese encephalitis virus)|taxid:11072(Japanese encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422800|imex:IM-24738-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	ensembl:ENSG00000058404(gene)|ensembl:ENST00000395749(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014733"(regulation of skeletal muscle adaptation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|refseq:NP_001211.3|refseq:NP_742075.1|refseq:NP_742076.1|refseq:NP_742077.1|refseq:NP_742078.1|refseq:NP_742079.1|refseq:NP_742080.1|refseq:NP_742081.1|mint:Q13554|rcsb pdb:3BHH|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442729|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|interpro:IPR032710|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001280099.1|dip:DIP-39770N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:j+swWwyqabf1+ccBM10YutAzZNg11072	rogid:3RDzSxLdoGtWTECo9At60gEZfZY9606	intact-crc:3ADEA6EF1820D9FE|rigid:cdYr9wxX79f3cTLuaNTwjlfzkzg	false	binding-associated region:1521-1672("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q96S94	intact:EBI-11422701	intact:EBI-1045974|uniprotkb:Q5T2N5|uniprotkb:Q5T2N6|uniprotkb:Q6IQ12|uniprotkb:Q7Z4Z8|uniprotkb:Q8N3C9|uniprotkb:Q8N3D5|uniprotkb:Q8NHE3|uniprotkb:Q8TEL0|uniprotkb:Q96B00|uniprotkb:A8K8A3|uniprotkb:B1B152|ensembl:ENSP00000383611|uniprotkb:A0A024R072|uniprotkb:A0A024R077|uniprotkb:A0A0C4DGC4|uniprotkb:F2Z3J5	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:ccnl2_human(display_long)|uniprotkb:Paneth cell-enhanced expression protein(gene name synonym)|uniprotkb:CCNL2(gene name)|psi-mi:CCNL2(display_short)|uniprotkb:SB138(orf name)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422864|imex:IM-24738-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:XP_016857911.1|refseq:NP_001034666.1|refseq:NP_112199.2|ensembl:ENSG00000221978(gene)|ensembl:ENST00000400809(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|refseq:XP_011540523.1|refseq:NP_001307082.1|refseq:NP_001307084.1	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:/S4YX8LH+cn3dzUKBB2VL52xl2M9606	intact-crc:BC9BEB3E0D3C53DA|rigid:fGWGZmtBHUQO+tN8YMcYIeBhTl0	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q96EA4	intact:EBI-11422591	intact:EBI-715381|uniprotkb:Q8TEC8|uniprotkb:Q9HD44|uniprotkb:Q9NX97|uniprotkb:C9JS47|ensembl:ENSP00000265295|uniprotkb:B4E393	psi-mi:polg_alkv(display_long)	psi-mi:spdly_human(display_long)|uniprotkb:SPDL1(gene name)|psi-mi:SPDL1(display_short)|uniprotkb:Arsenite-related gene 1 protein(gene name synonym)|uniprotkb:CCDC99(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 99(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.4A(gene name synonym)|uniprotkb:Spindle apparatus coiled-coil domain-containing protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422856|imex:IM-24738-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_060255.3|ensembl:ENSG00000040275(gene)|ensembl:ENST00000265295(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|interpro:IPR028593|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001316570.1|dip:DIP-47296N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:CzXKB2VOL2ZBmQjyc4vGxQ0cTnY9606	intact-crc:7A15684E774C84E4|rigid:4ZADF/CoXpm5Baw3Vt0OZH6Bksc	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q96EA4	intact:EBI-11422640	intact:EBI-715381|uniprotkb:Q8TEC8|uniprotkb:Q9HD44|uniprotkb:Q9NX97|uniprotkb:C9JS47|ensembl:ENSP00000265295|uniprotkb:B4E393	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:spdly_human(display_long)|uniprotkb:SPDL1(gene name)|psi-mi:SPDL1(display_short)|uniprotkb:Arsenite-related gene 1 protein(gene name synonym)|uniprotkb:CCDC99(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 99(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.4A(gene name synonym)|uniprotkb:Spindle apparatus coiled-coil domain-containing protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422848|imex:IM-24738-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_060255.3|ensembl:ENSG00000040275(gene)|ensembl:ENST00000265295(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|interpro:IPR028593|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001316570.1|dip:DIP-47296N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:CzXKB2VOL2ZBmQjyc4vGxQ0cTnY9606	intact-crc:2DC39E1D73B52CB6|rigid:8sePrPleyDn8P05kXnJfsiRoQA0	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15078	uniprotkb:Q8JU44	intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012	intact:EBI-11422899	psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym)	psi-mi:q8ju44_wnv(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11082(wnv)|taxid:11082("West Nile virus (WNV)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422896|imex:IM-24738-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606	rogid:mdfiq0WiTL7ROreWCK7Vp3c+dLo11082	intact-crc:2EAA67ECEE2C2C3F|rigid:TxtUdt+gyFxEs4RucDV1PNXQRp0	false	-	binding-associated region:2781-3428("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9BV73	intact:EBI-11422591	intact:EBI-1053100|uniprotkb:O14812|uniprotkb:O60588|uniprotkb:Q9H450|uniprotkb:E1P5Q3|ensembl:ENSP00000380661	psi-mi:polg_alkv(display_long)	psi-mi:cp250_human(display_long)|uniprotkb:Centrosomal protein 2(gene name synonym)|uniprotkb:Centrosomal Nek2-associated protein 1(gene name synonym)|uniprotkb:CEP250(gene name)|psi-mi:CEP250(display_short)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CNAP1(gene name synonym)|uniprotkb:250 kDa centrosomal protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422888|imex:IM-24738-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_009117.2|dip:DIP-39406N|refseq:NP_001305148.1|refseq:XP_005260319.1|refseq:XP_006723753.1|refseq:XP_006723754.1|refseq:XP_006723755.1|refseq:XP_006723756.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|mint:Q9BV73|rcsb pdb:6OQA|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000126001(gene)|ensembl:ENST00000397527(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060271"(cilium assembly)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:We+5inOR7merXjzOl/vRehewlFA9606	intact-crc:7CF657A77F6DB9A9|rigid:4gsQ31ubDKZnDnN7hzdlsTQ+baM	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:Q9BV73	intact:EBI-11361108	intact:EBI-1053100|uniprotkb:O14812|uniprotkb:O60588|uniprotkb:Q9H450|uniprotkb:E1P5Q3|ensembl:ENSP00000380661	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:cp250_human(display_long)|uniprotkb:Centrosomal protein 2(gene name synonym)|uniprotkb:Centrosomal Nek2-associated protein 1(gene name synonym)|uniprotkb:CEP250(gene name)|psi-mi:CEP250(display_short)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CNAP1(gene name synonym)|uniprotkb:250 kDa centrosomal protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422880|imex:IM-24738-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_009117.2|dip:DIP-39406N|refseq:NP_001305148.1|refseq:XP_005260319.1|refseq:XP_006723753.1|refseq:XP_006723754.1|refseq:XP_006723755.1|refseq:XP_006723756.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|mint:Q9BV73|rcsb pdb:6OQA|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000126001(gene)|ensembl:ENST00000397527(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060271"(cilium assembly)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:We+5inOR7merXjzOl/vRehewlFA9606	intact-crc:F0C0C79D41E703D1|rigid:ZsuF0UQSwK6hjYyPPZ9dgA0ykzU	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P55287	intact:EBI-11422591	intact:EBI-1754095|uniprotkb:A8MZC8|uniprotkb:Q15065|uniprotkb:Q15066|uniprotkb:Q9UQ93|uniprotkb:Q9UQ94|uniprotkb:A8K5D6|uniprotkb:B7WP28|ensembl:ENSP00000268603	psi-mi:polg_alkv(display_long)	psi-mi:cad11_human(display_long)|uniprotkb:CDH11(gene name)|psi-mi:CDH11(display_short)|uniprotkb:Osteoblast cadherin(gene name synonym)|uniprotkb:OSF-4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422872|imex:IM-24738-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:XP_011521105.1|refseq:NP_001788.2|refseq:NP_001295321.1|ensembl:ENSG00000140937(gene)|ensembl:ENST00000268603(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|reactome:R-HSA-418990|refseq:XP_005255818.1|refseq:XP_005255819.1|refseq:XP_005255820.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:Q1WNdOFoMB2ItSXG55xVxGkQ+UM9606	intact-crc:A27B5CEDFE29390C|rigid:9Lf2DICQY8B/YvyFE/5bHGYxNj0	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:P30622	intact:EBI-11422701	intact:EBI-2683569|uniprotkb:A0AVD3|uniprotkb:Q29RG0|uniprotkb:Q17RS4|ensembl:ENSP00000479322	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:clip1_human(display_long)|uniprotkb:CYLN1(gene name synonym)|uniprotkb:RSN(gene name synonym)|uniprotkb:Cytoplasmic linker protein 1(gene name synonym)|uniprotkb:Cytoplasmic linker protein 170 alpha-2(gene name synonym)|uniprotkb:Reed-Sternberg intermediate filament-associated protein(gene name synonym)|uniprotkb:Restin(gene name synonym)|uniprotkb:CLIP1(gene name)|psi-mi:CLIP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422942|imex:IM-24738-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_002947.1|refseq:NP_937883.1|refseq:NP_001234926.1|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR032108|interpro:IPR036859|mint:P30622|rcsb pdb:2CP5|rcsb pdb:2CP6|rcsb pdb:2E3H|rcsb pdb:2E3I|rcsb pdb:2E4H|rcsb pdb:2HQH|rcsb pdb:2QK0|rcsb pdb:3E2U|rcsb pdb:3RDV|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000130779(gene)|ensembl:ENST00000620786(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031116"(positive regulation of microtubule polymerization)|refseq:XP_016875275.1|refseq:XP_016875279.1|dip:DIP-42826N	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:MqpHl9SGApxmKI7HWfN3gxyK3Cg9606	intact-crc:E56D429E7F54EA73|rigid:GIe3U1fXHOFQSiBJ8iysRXEM94U	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q12873	intact:EBI-11422701	intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422934|imex:IM-24738-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:UjefFUXiV28qhOP9BoIUansxl+k9606	intact-crc:F97EEEA31D460AE7|rigid:31GWRXpS2mP9CnsmLYUBJ07+a7w	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q96MT8	intact:EBI-11422582	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422926|imex:IM-24738-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	intact-crc:3FC4CC3B69BA2DEF|rigid:60UiQUQYL/Ns93riwLiBNaQduP4	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QXP6	uniprotkb:Q96MT8	intact:EBI-11422617	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896	psi-mi:q8qxp6_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11072(japanese encephalitis virus)|taxid:11072(Japanese encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422918|imex:IM-24738-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:j+swWwyqabf1+ccBM10YutAzZNg11072	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	intact-crc:00229945F96B6FA6|rigid:sqsFiBoucbqzAyu572RguHVCEro	false	binding-associated region:1521-1672("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MT8	uniprotkb:Q9E7P0	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896	intact:EBI-11361108	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422910|imex:IM-24738-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:E8E40ED25D450F43|rigid:xotGJH3TJQli6RBBz+5MHiWV1c0	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q8WXU2	intact:EBI-11422582	intact:EBI-2946907|uniprotkb:Q8N1S6|ensembl:ENSP00000299561|ensembl:ENSP00000323275|uniprotkb:Q6P5Y9	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:daaf4_human(display_long)|uniprotkb:DNAAF4(gene name)|psi-mi:DNAAF4(display_short)|uniprotkb:DYX1C1(gene name synonym)|uniprotkb:Dyslexia susceptibility 1 candidate gene 1 protein(gene name synonym)|uniprotkb:EKN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422982|imex:IM-24738-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSG00000256061(gene)|ensembl:ENST00000321149(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003341"(cilium movement)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|ensembl:ENST00000348518(transcript)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR037894|mint:Q8WXU2|refseq:NP_001028731.1|refseq:NP_001028732.1|refseq:NP_570722.2	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:Yy8tSogV3e0WCjw4OOGgf79zQ149606	intact-crc:3402DB5C02E3C161|rigid:Ecd12/HSoIcIwg0Wb7cAEZ1ahU8	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:O14641	intact:EBI-11422701	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422974|imex:IM-24738-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:715843E9B09AD097|rigid:7muo9SNoB3q5rR3CJltZjvUCF64	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q5QJE6	intact:EBI-11422640	intact:EBI-5666736|ensembl:ENSP00000411010|uniprotkb:Q53H59|uniprotkb:Q86WX9|uniprotkb:Q76MJ8|uniprotkb:Q12987|uniprotkb:Q6TLI0|uniprotkb:Q5TFJ4	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:tdif2_human(display_long)|uniprotkb:ERBP(gene name synonym)|uniprotkb:Estrogen receptor-binding protein(gene name synonym)|uniprotkb:LPTS-interacting protein 2(gene name synonym)|uniprotkb:TDIF2(gene name synonym)|uniprotkb:Terminal deoxynucleotidyltransferase-interacting factor 2(gene name synonym)|uniprotkb:DNTTIP2(gene name)|psi-mi:DNTTIP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422966|imex:IM-24738-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000067334(gene)|ensembl:ENST00000436063(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR014810(Fcf2 pre-rRNA processing)|interpro:IPR039883|refseq:NP_055412.2	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:GSN2/hZ+HZb29LuBvv2RVMawmNA9606	intact-crc:7CD5A8402A83FC26|rigid:hDfYeizuNyTIsuJPmlEbyksa5wc	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q5QJE6	intact:EBI-11422591	intact:EBI-5666736|ensembl:ENSP00000411010|uniprotkb:Q53H59|uniprotkb:Q86WX9|uniprotkb:Q76MJ8|uniprotkb:Q12987|uniprotkb:Q6TLI0|uniprotkb:Q5TFJ4	psi-mi:polg_alkv(display_long)	psi-mi:tdif2_human(display_long)|uniprotkb:ERBP(gene name synonym)|uniprotkb:Estrogen receptor-binding protein(gene name synonym)|uniprotkb:LPTS-interacting protein 2(gene name synonym)|uniprotkb:TDIF2(gene name synonym)|uniprotkb:Terminal deoxynucleotidyltransferase-interacting factor 2(gene name synonym)|uniprotkb:DNTTIP2(gene name)|psi-mi:DNTTIP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422958|imex:IM-24738-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000067334(gene)|ensembl:ENST00000436063(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR014810(Fcf2 pre-rRNA processing)|interpro:IPR039883|refseq:NP_055412.2	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:GSN2/hZ+HZb29LuBvv2RVMawmNA9606	intact-crc:7E7ED9094FEAF8DD|rigid:ZzxgJlvEK3G1ftSvRUgDdF1LxQU	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:P50570	intact:EBI-11422668	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422950|imex:IM-24738-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:8A91B66708DC28D5|rigid:IE2oOSOeGX3kO8h3ASBguOYftM8	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P06733	intact:EBI-11422582	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423022|imex:IM-24738-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:0262A9B64B369409|rigid:y8C01EqW2IrmIx934pK2k4JZvHk	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:P06733	intact:EBI-11361108	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423014|imex:IM-24738-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:17018B0023C81E2E|rigid:FfqMxiDsDGBP5KX/h/J0AzqrUAc	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q9Y6C2	intact:EBI-11422640	intact:EBI-744586|ensembl:ENSP00000369677|uniprotkb:A0A0C4DFX3|intact:EBI-902920|uniprotkb:A5PL03|uniprotkb:H0Y7A0|uniprotkb:Q53SY9|uniprotkb:Q96G58|uniprotkb:Q96IH6|uniprotkb:Q9UG76	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:emil1_human(display_long)|uniprotkb:EMILIN1(gene name)|psi-mi:EMILIN1(display_short)|uniprotkb:EMI(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423006|imex:IM-24738-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|mint:Q9Y6C2|rcsb pdb:2KA3|rcsb pdb:2OII|reactome:R-HSA-2129379|ensembl:ENSG00000138080(gene)|ensembl:ENST00000380320(transcript)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050866"(negative regulation of cell activation)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0098640"(integrin binding involved in cell-matrix adhesion)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1904027"(negative regulation of collagen fibril organization)|go:"GO:1905522"(negative regulation of macrophage migration)|go:"GO:1990971"(EMILIN complex)|refseq:NP_008977.1|dip:DIP-35733N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2017/10/20	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:lJnDOaq3HA5TUGd1Skz/1s3DIxM9606	intact-crc:C97B467DC6CF072F|rigid:E+QlrOc/GXPDVI6bl7E7Es+f9+Y	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P63241	intact:EBI-11422582	intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422998|imex:IM-24738-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606	intact-crc:C515D55D42707EEE|rigid:ayl3TLTr7iKU5E+6pjarHogmlgY	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q99848	intact:EBI-11422701	intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11422990|imex:IM-24738-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606	intact-crc:C31DB3EF8DE343FA|rigid:QeGELt3i6SCy4lhU306o/tKm1dQ	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NB25	uniprotkb:Q9E7P0	intact:EBI-9917523|uniprotkb:B9DI75|uniprotkb:Q5TBS9|uniprotkb:Q96GY8|uniprotkb:Q9H851|uniprotkb:Q7Z323|uniprotkb:Q9H0J8|uniprotkb:F8W8D6|ensembl:ENSP00000342604	intact:EBI-11361108	psi-mi:f184a_human(display_long)|uniprotkb:C6orf60(gene name synonym)|uniprotkb:FAM184A(gene name)|psi-mi:FAM184A(display_short)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423062|imex:IM-24738-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093881.1|refseq:NP_001275505.1|refseq:NP_078857.5|ensembl:ENSG00000111879(gene)|ensembl:ENST00000338891(transcript)|go:"GO:0005615"(extracellular space)|interpro:IPR029605|interpro:IPR029607|interpro:IPR039478	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:A9gX4FWK+lMGWE31zzMr1cszuHg9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:851CE699EA38369F|rigid:vbPmvkaeVOpSNN1GvPuq4h50lOE	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q03112	intact:EBI-11422701	intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423054|imex:IM-24738-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2018/04/06	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606	intact-crc:AC4D5DA181B1B3B5|rigid:uhZCAdUhlkKSNBgUvHQ/ELtBYZs	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:Q16206	intact:EBI-11361108	intact:EBI-744159|uniprotkb:Q5VTJ1|uniprotkb:Q5VTJ2|uniprotkb:Q8WUX0|uniprotkb:Q9NTP6|uniprotkb:Q9UH82|intact:EBI-2623308|uniprotkb:A8K197|uniprotkb:A8K1C2|ensembl:ENSP00000337146|ensembl:ENSP00000359965	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:enox2_human(display_long)|uniprotkb:Tumor-associated hydroquinone oxidase(gene name synonym)|uniprotkb:Cytosolic ovarian carcinoma antigen 1(gene name synonym)|uniprotkb:APK1 antigen(gene name synonym)|uniprotkb:ENOX2(gene name)|psi-mi:ENOX2(display_short)|uniprotkb:COVA1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423046|imex:IM-24738-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_006366.2|refseq:NP_872114.1|refseq:XP_011529549.1|refseq:XP_011529551.1|refseq:XP_011529553.1|refseq:NP_001268665.1|refseq:XP_005262411.1|mint:Q16206|interpro:IPR038876|ensembl:ENST00000338144(transcript)|ensembl:ENST00000370927(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007624"(ultradian rhythm)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0022900"(electron transport chain)|go:"GO:0040008"(regulation of growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034140|interpro:IPR035979|ensembl:ENSG00000165675(gene)|refseq:XP_016884715.1|refseq:XP_016884716.1|refseq:XP_016884717.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:nqvZJv5GYe49nv+r4Bda6aRZ/mU9606	intact-crc:08EBAA0E3FB0EBC4|rigid:+4SV/I3nNtfOQmJxElzzDHJbTeg	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P06733	intact:EBI-11422640	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423038|imex:IM-24738-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:A3AE339CB147E0CA|rigid:TlKm1GHzy50d/Bp6Z44om5kw/3Q	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P06733	intact:EBI-11422591	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:polg_alkv(display_long)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423030|imex:IM-24738-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:A10542D5D42EE431|rigid:BLCHMX/mVNJ7MreQ5AD2UolnrbE	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q9UJY5	intact:EBI-11422582	intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423106|imex:IM-24738-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606	intact-crc:AA5C95F9886ED7E3|rigid:Okq1anZxoeXi37shTG3nJGY9VHk	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:Q9UJY5	intact:EBI-11361108	intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423098|imex:IM-24738-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606	intact-crc:5F04CE3A3968301C|rigid:Hn1indQC4BW1Sq+d6HaYhyTKjCw	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q14192	intact:EBI-11422591	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	psi-mi:polg_alkv(display_long)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423090|imex:IM-24738-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:A2D9609BD060228B|rigid:jyPrmyR/luiholVNetWlLcwWOC0	false	binding-associated region:1509-1661("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q6ZTR7	intact:EBI-11422701	intact:EBI-11423078|ensembl:ENSP00000487117|uniprotkb:A0A0D9SG36	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:cbar2_human(display_long)|uniprotkb:CIBAR2(gene name)|psi-mi:CIBAR2(display_short)|uniprotkb:FAM92B(gene name synonym)|uniprotkb:Protein FAM92B(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423082|imex:IM-24738-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_940893.1|refseq:XP_011521365.1|ensembl:ENSG00000153789(gene)|ensembl:ENST00000629253(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0030030"(cell projection organization)|go:"GO:0042995"(cell projection)|interpro:IPR009602(Protein of unknown function DUF1208)|interpro:IPR027267|interpro:IPR035590	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2017/05/26	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:c6PW0x+frLN9b4oGGPoYB6IRZ8o9606	intact-crc:976EAD3F57A2B278|rigid:WzXpACHEainX8Dh6/+/vkwz0pTY	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q8NB25	intact:EBI-11422640	intact:EBI-9917523|uniprotkb:B9DI75|uniprotkb:Q5TBS9|uniprotkb:Q96GY8|uniprotkb:Q9H851|uniprotkb:Q7Z323|uniprotkb:Q9H0J8|uniprotkb:F8W8D6|ensembl:ENSP00000342604	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:f184a_human(display_long)|uniprotkb:C6orf60(gene name synonym)|uniprotkb:FAM184A(gene name)|psi-mi:FAM184A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423070|imex:IM-24738-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001093881.1|refseq:NP_001275505.1|refseq:NP_078857.5|ensembl:ENSG00000111879(gene)|ensembl:ENST00000338891(transcript)|go:"GO:0005615"(extracellular space)|interpro:IPR029605|interpro:IPR029607|interpro:IPR039478	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:A9gX4FWK+lMGWE31zzMr1cszuHg9606	intact-crc:0D2A873DBB2638A4|rigid:Emgg6YSnTQ2rXtMoIV1HbfcablE	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q76N89	intact:EBI-11422701	intact:EBI-949582|ensembl:ENSP00000379228|uniprotkb:O15036|uniprotkb:Q9HCC7|uniprotkb:A7E2X0|uniprotkb:A8MYS3|uniprotkb:B4DH42|intact:EBI-11059486	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:hecw1_human(display_long)|uniprotkb:HECT, C2 and WW domain-containing protein 1(gene name synonym)|uniprotkb:NEDD4-like E3 ubiquitin-protein ligase 1(gene name synonym)|uniprotkb:HECW1(gene name)|psi-mi:HECW1(display_short)|uniprotkb:KIAA0322(gene name synonym)|uniprotkb:NEDL1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECW1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423138|imex:IM-24738-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR032348|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|interpro:IPR037795|interpro:IPR040524|mint:Q76N89|rcsb pdb:3L4H|reactome:R-HSA-4641258|ensembl:ENSG00000002746(gene)|ensembl:ENST00000395891(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_055867.3|refseq:NP_001273988.1|refseq:XP_016867375.1|refseq:XP_016867378.1	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:iK0wuIJT5WCj76JVf435fZeARkc9606	intact-crc:7628CC23BCF574E1|rigid:2wo4o3x0HKUSd9P5r29jlsHSqG0	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P28799	intact:EBI-11422640	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423130|imex:IM-24738-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	intact-crc:B56D33683C1D85CC|rigid:wu5PKsbRdfa2Wvd888PnWLknCGg	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P28799	intact:EBI-11422591	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	psi-mi:polg_alkv(display_long)	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423122|imex:IM-24738-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	intact-crc:B7C6422159748137|rigid:GC838WdQaPey4+qAVl+e6V64Uos	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q9HD26	intact:EBI-11422640	intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423114|imex:IM-24738-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001017408.1|refseq:NP_065132.1|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045176"(apical protein localization)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|go:"GO:0042802"(identical protein binding)|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|reactome:R-HSA-5627083|reactome:R-HSA-9013406|ensembl:ENSG00000047932(gene)|ensembl:ENST00000368498(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032991"(protein-containing complex)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606	intact-crc:01241DD61E55D2F4|rigid:xICRcJIAR22Knhw/RbF4Jhag7Wg	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:Q06033	intact:EBI-11422668	intact:EBI-3929079|uniprotkb:Q53F06|uniprotkb:Q99085|uniprotkb:Q6LAM2|uniprotkb:Q3B7H5|ensembl:ENSP00000415769	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:itih3_human(display_long)|uniprotkb:ITIH3(gene name)|psi-mi:ITIH3(display_short)|uniprotkb:Serum-derived hyaluronan-associated protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423178|imex:IM-24738-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	ensembl:ENSG00000162267(gene)|ensembl:ENST00000449956(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010600(Inter-alpha-trypsin inhibitor heavy chain, C-terminal)|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR036465|reactome:R-HSA-114608|refseq:NP_002208.3	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:49DpVdxzBD/i6gV9hjp5IYyJ0oE9606	intact-crc:CCD9DDBBA57671CF|rigid:JzCaXC/vv/qkU98nuRiFExmlqWk	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12906	uniprotkb:Q9E7P0	intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5	intact:EBI-11361108	psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423170|imex:IM-24738-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:59884B362E26C429|rigid:c/qY2rEjaUX8i6TvwPOd8XX08IU	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P08238	intact:EBI-11422582	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423162|imex:IM-24738-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	intact-crc:2212FFC6F3808680|rigid:Mta4q0iESUSHplEW5j0RQF9CKrU	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P31942	intact:EBI-11422591	intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1	psi-mi:polg_alkv(display_long)	psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423154|imex:IM-24738-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606	intact-crc:EFA65292EA050072|rigid:UwkFvpgMy/3y79WYb/RksCC8lkI	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P52597	intact:EBI-11422640	intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423146|imex:IM-24738-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606	intact-crc:669C1475C65D71DB|rigid:U6A9LPvCZ0vDE1Ka0yXwfXzNb20	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	intact:EBI-11423213	intact:EBI-11422591	-	psi-mi:polg_alkv(display_long)	psi-mi:o16(display_short)|psi-mi:EBI-11423213(display_long)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423210|imex:IM-24738-80	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	uniprotkb:O16(uniprot-removed-ac)	psi-mi:"MI:0471"(mint)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	-	intact-crc:F43E7B0A25D414A4	false	binding-associated region:1509-1661("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q92993	intact:EBI-11422640	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423202|imex:IM-24738-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	intact-crc:D0F141838FB61173|rigid:PBLt8bnm0VYedoxU1q25+0bcOUM	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P78504	intact:EBI-11422640	intact:EBI-2847071|uniprotkb:B4DYR1|uniprotkb:E9PCF9|uniprotkb:O14902|uniprotkb:A0AV43|uniprotkb:O15122|uniprotkb:Q15816|ensembl:ENSP00000254958	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:jag1_human(display_long)|uniprotkb:JAG1(gene name)|psi-mi:JAG1(display_short)|uniprotkb:JAGL1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423194|imex:IM-24738-78	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:XP_016883196.1|refseq:NP_000205.1|ensembl:ENST00000254958(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007399"(nervous system development)|ensembl:ENSG00000101384(gene)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061309"(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061444"(endocardial cushion cell development)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0072006"(nephron development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072017"(distal tubule development)|go:"GO:0072070"(loop of Henle development)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|go:"GO:0008083"(growth factor activity)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|interpro:IPR033108|rcsb pdb:2KB9|rcsb pdb:2VJ2|rcsb pdb:4CBZ|rcsb pdb:4CC0|rcsb pdb:4CC1|rcsb pdb:4XI7|rcsb pdb:5BO1|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-8941856|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9013507|reactome:R-HSA-9013700|interpro:IPR001881(EGF-like calcium-binding)|dip:DIP-46371N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:kaBPZjsO7mchlR6vYIknqvTluos9606	intact-crc:5C7E9C28586F9F57|rigid:zIsn+hM6nwnhCihuuh00eCw7VkQ	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P78504	intact:EBI-11422591	intact:EBI-2847071|uniprotkb:B4DYR1|uniprotkb:E9PCF9|uniprotkb:O14902|uniprotkb:A0AV43|uniprotkb:O15122|uniprotkb:Q15816|ensembl:ENSP00000254958	psi-mi:polg_alkv(display_long)	psi-mi:jag1_human(display_long)|uniprotkb:JAG1(gene name)|psi-mi:JAG1(display_short)|uniprotkb:JAGL1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423186|imex:IM-24738-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:XP_016883196.1|refseq:NP_000205.1|ensembl:ENST00000254958(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007399"(nervous system development)|ensembl:ENSG00000101384(gene)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061309"(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061444"(endocardial cushion cell development)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0072006"(nephron development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072017"(distal tubule development)|go:"GO:0072070"(loop of Henle development)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|go:"GO:0008083"(growth factor activity)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|interpro:IPR033108|rcsb pdb:2KB9|rcsb pdb:2VJ2|rcsb pdb:4CBZ|rcsb pdb:4CC0|rcsb pdb:4CC1|rcsb pdb:4XI7|rcsb pdb:5BO1|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-8941856|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9013507|reactome:R-HSA-9013700|interpro:IPR001881(EGF-like calcium-binding)|dip:DIP-46371N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:kaBPZjsO7mchlR6vYIknqvTluos9606	intact-crc:5ED5ED613D069BAC|rigid:rt1tkLF0jDkmsHowgXRh/tvXmSU	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:P02545	intact:EBI-11361108	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423244|imex:IM-24738-84	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	intact-crc:AC89EB22758103DD|rigid:hlzErjg3yoRor/04Js/gY/NFM5s	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P55268	intact:EBI-11422640	intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423236|imex:IM-24738-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606	intact-crc:F1DE163A7F0531D3|rigid:LscV7GKXlgPS1Yd4i7gIE9iDf3U	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P55268	intact:EBI-11422591	intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325	psi-mi:polg_alkv(display_long)	psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423228|imex:IM-24738-82	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606	intact-crc:F37567731A6C3528|rigid:xvPato2iYWzsjg26BV1ZdF/vtXw	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P08727	intact:EBI-11422582	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423220|imex:IM-24738-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	intact-crc:F9AC63AA650AC67D|rigid:XgNrocyt0G4NAf4KsCMHV22Y4aE	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q99750	intact:EBI-11422591	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:polg_alkv(display_long)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423276|imex:IM-24738-88	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:F1AA62128736C05D|rigid:g1g8HFkl491bHPkHrPjtPZwCIzc	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q96CN5	intact:EBI-11422591	intact:EBI-2805176|ensembl:ENSP00000306760	psi-mi:polg_alkv(display_long)	psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423252|imex:IM-24738-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000169683(gene)|ensembl:ENST00000306688(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|refseq:NP_659436.1|dip:DIP-29482N	psi-mi:"MI:0471"(mint)	-	crc64:27F5D210721459FB	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606	intact-crc:79F2A96EE7E40B1F|rigid:J0yP0xPL/M/32DERO1tJrwhYbPg	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:P43243	intact:EBI-11422668	intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423268|imex:IM-24738-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	intact-crc:CF82FF898CE3CE89|rigid:qEUNR2fJk8hVd3G0xVpT5mAblmU	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9NS15	intact:EBI-11422591	intact:EBI-3927098|uniprotkb:Q9H7K2|uniprotkb:Q96HB9|uniprotkb:Q9UFN4|uniprotkb:O15107|ensembl:ENSP00000301873	psi-mi:polg_alkv(display_long)	psi-mi:ltbp3_human(display_long)|uniprotkb:LTBP3(gene name)|psi-mi:LTBP3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423260|imex:IM-24738-86	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001123616.1|refseq:NP_001157738.1|refseq:NP_066548.2|go:"GO:0036363"(transforming growth factor beta activation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046849"(bone remodeling)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060430"(lung saccule development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902462"(positive regulation of mesenchymal stem cell proliferation)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|mint:Q9NS15|reactome:R-HSA-2129379|ensembl:ENSG00000168056(gene)|ensembl:ENST00000301873(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:wTlw1eFDbHiWYm9/2sgGxqK1uI49606	intact-crc:E3FA94364C36CE7C|rigid:KwF4FL39dC5e46E6cSox+5jc4cs	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q9NPJ6	intact:EBI-11422701	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423284|imex:IM-24738-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:1BCA13DF2D6B5A62|rigid:W6Ng056lVvvLxyY+Jjy4GTT4sHM	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9BV36	intact:EBI-11422591	intact:EBI-7042162|uniprotkb:B4DKW7|intact:MINT-3388002|uniprotkb:Q9HA71|uniprotkb:B3KSS2|uniprotkb:G5E9G5|ensembl:ENSP00000264605	psi-mi:polg_alkv(display_long)	psi-mi:melph_human(display_long)|uniprotkb:MLPH(gene name)|psi-mi:MLPH(display_short)|uniprotkb:SLAC2A(gene name synonym)|uniprotkb:Exophilin-3(gene name synonym)|uniprotkb:Synaptotagmin-like protein 2a(gene name synonym)|uniprotkb:Slp homolog lacking C2 domains a(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423300|imex:IM-24738-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_077006.1|refseq:NP_001035932.1|refseq:NP_001268402.1|refseq:NP_001268403.1|dip:DIP-44046N|ensembl:ENSG00000115648(gene)|ensembl:ENST00000264605(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0017022"(myosin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006788("Myelin-associated oligodendrocytic basic protein (MOBP)")|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037442|interpro:IPR041282|mint:Q9BV36	psi-mi:"MI:0471"(mint)	-	comment:mint|function:Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A|function:"Defects in MLPH are a cause of Griscelli syndrome type-3 (GS3) [MIM:609227]. GS3 is a rare autosomal recessive disorder characterized by pigmentary dilution of the skin and hair, the presence of large clumps of pigment in hair shafts, and an accumulation of melanosomes in melanocytes, without other clinical manifestations"	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:g6+punuQGoilMzUlkOu+V73nUHc9606	intact-crc:CB39EE422B76C803|rigid:pbDJAUeB/n+3/BOLVkhX4dVqBHo	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:Q9BV36	intact:EBI-11422668	intact:EBI-7042162|uniprotkb:B4DKW7|intact:MINT-3388002|uniprotkb:Q9HA71|uniprotkb:B3KSS2|uniprotkb:G5E9G5|ensembl:ENSP00000264605	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:melph_human(display_long)|uniprotkb:MLPH(gene name)|psi-mi:MLPH(display_short)|uniprotkb:SLAC2A(gene name synonym)|uniprotkb:Exophilin-3(gene name synonym)|uniprotkb:Synaptotagmin-like protein 2a(gene name synonym)|uniprotkb:Slp homolog lacking C2 domains a(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423308|imex:IM-24738-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_077006.1|refseq:NP_001035932.1|refseq:NP_001268402.1|refseq:NP_001268403.1|dip:DIP-44046N|ensembl:ENSG00000115648(gene)|ensembl:ENST00000264605(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0017022"(myosin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006788("Myelin-associated oligodendrocytic basic protein (MOBP)")|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037442|interpro:IPR041282|mint:Q9BV36	psi-mi:"MI:0471"(mint)	-	comment:mint|function:Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A|function:"Defects in MLPH are a cause of Griscelli syndrome type-3 (GS3) [MIM:609227]. GS3 is a rare autosomal recessive disorder characterized by pigmentary dilution of the skin and hair, the presence of large clumps of pigment in hair shafts, and an accumulation of melanosomes in melanocytes, without other clinical manifestations"	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:g6+punuQGoilMzUlkOu+V73nUHc9606	intact-crc:A224CCC71FD0D9A6|rigid:C3f/RDa/Q1UHvqkC/NfeAcBU8eA	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q9BV36	intact:EBI-11422640	intact:EBI-7042162|uniprotkb:B4DKW7|intact:MINT-3388002|uniprotkb:Q9HA71|uniprotkb:B3KSS2|uniprotkb:G5E9G5|ensembl:ENSP00000264605	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:melph_human(display_long)|uniprotkb:MLPH(gene name)|psi-mi:MLPH(display_short)|uniprotkb:SLAC2A(gene name synonym)|uniprotkb:Exophilin-3(gene name synonym)|uniprotkb:Synaptotagmin-like protein 2a(gene name synonym)|uniprotkb:Slp homolog lacking C2 domains a(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423292|imex:IM-24738-90	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_077006.1|refseq:NP_001035932.1|refseq:NP_001268402.1|refseq:NP_001268403.1|dip:DIP-44046N|ensembl:ENSG00000115648(gene)|ensembl:ENST00000264605(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0017022"(myosin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006788("Myelin-associated oligodendrocytic basic protein (MOBP)")|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037442|interpro:IPR041282|mint:Q9BV36	psi-mi:"MI:0471"(mint)	-	comment:mint|function:Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A|function:"Defects in MLPH are a cause of Griscelli syndrome type-3 (GS3) [MIM:609227]. GS3 is a rare autosomal recessive disorder characterized by pigmentary dilution of the skin and hair, the presence of large clumps of pigment in hair shafts, and an accumulation of melanosomes in melanocytes, without other clinical manifestations"	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:g6+punuQGoilMzUlkOu+V73nUHc9606	intact-crc:9CEF18112F8F6051|rigid:z2o3KZbAqlp+HouUG2bLPkT8IvU	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P35579	intact:EBI-11422591	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:polg_alkv(display_long)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423324|imex:IM-24738-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:1DAA1211A33964A6|rigid:/u05pJ4VCH8vFJaz+gJJg87/djU	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:P35579	intact:EBI-11422668	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423332|imex:IM-24738-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:1FCED92B600E8908|rigid:OpT3bbfmSsDln0gbgJQlVc18738	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8JU44	uniprotkb:Q9BYC9	intact:EBI-11422899	intact:EBI-714361|uniprotkb:B2RE41|ensembl:ENSP00000341082|uniprotkb:B7Z746	psi-mi:q8ju44_wnv(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rm20_human(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL20m(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11082(wnv)|taxid:11082("West Nile virus (WNV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423316|imex:IM-24738-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	rcsb pdb:7OF4|rcsb pdb:7OG4|refseq:NP_060441.2|ensembl:ENSG00000242485(gene)|ensembl:ENST00000344843(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR005813(Ribosomal protein L20)|interpro:IPR035566|mint:Q9BYC9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:6VMI|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:mdfiq0WiTL7ROreWCK7Vp3c+dLo11082	rogid:x96Ntk82ZbcbF8ksg84k0sHgINc9606	intact-crc:4D2D7722E5B94C9B|rigid:UED8JPYwToB0AK4GGnZaYwlTzQk	false	binding-associated region:2781-3428("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9BPW8	intact:EBI-11422591	intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121	psi-mi:polg_alkv(display_long)	psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423372|imex:IM-24738-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606	intact-crc:ACEFE40875B9A435|rigid:wuuNMdwZQoRIGNyq85TRM1d+68E	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P25963	intact:EBI-11422582	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423364|imex:IM-24738-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	intact-crc:3D7AA4C276105BC9|rigid:FkvmftWaGbQoxkZz0yuJNTP6DMc	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25963	uniprotkb:Q9E7P0	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	intact:EBI-11361108	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423356|imex:IM-24738-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:4621299810D74737|rigid:pv06t6YecHuXrvM9onenbxNhvVk	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:Q7Z6G3	intact:EBI-11361108	intact:EBI-950070|ensembl:ENSP00000307449|uniprotkb:A2RRG3|uniprotkb:O75547|uniprotkb:Q6ZSK0|uniprotkb:H3BTW2	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:neca2_human(display_long)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)|uniprotkb:EFCBP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423348|imex:IM-24738-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	ensembl:ENSG00000103154(gene)|ensembl:ENST00000305202(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042984"(regulation of amyloid precursor protein biosynthetic process)|go:"GO:0060168"(positive regulation of adenosine receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR007138(Antibiotic biosynthesis monooxygenase)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039862|mint:Q7Z6G3|refseq:NP_061938.2|refseq:NP_001316678.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:Op/JNOBupSCF1U3MCeNmJ6gUUrg9606	intact-crc:CBAEFD82E2D53A1D|rigid:GurhRC6n4dfgH/Jv6BtTcA4X9u4	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P35579	intact:EBI-11422640	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423340|imex:IM-24738-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:1F016358C650605D|rigid:fZRC8SBOKJV6Bzk5HJtKlS8GnqQ	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5ERI7	uniprotkb:Q13232	intact:EBI-11422733	intact:EBI-713684|uniprotkb:Q9BWH4|ensembl:ENSP00000219302	psi-mi:q5eri7_wnv(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:ndk3_human(display_long)|uniprotkb:Nucleoside diphosphate kinase C(gene name synonym)|uniprotkb:nm23-H3(gene name synonym)|uniprotkb:DR-nm23(gene name synonym)|uniprotkb:NME3(gene name)|psi-mi:NME3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11082(wnv)|taxid:11082("West Nile virus (WNV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423410|imex:IM-24738-104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	ensembl:ENSG00000103024(gene)|ensembl:ENST00000219302(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q13232|rcsb pdb:1ZS6|reactome:R-HSA-499943|refseq:NP_002504.2|dip:DIP-49960N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:sncTVhdrW1RxLUewzsHEJmMs6WI11082	rogid:/egrHNJSuCILf6NdwwchG9rUGqI9606	intact-crc:2C7691BA824D6C2E|rigid:2auNiievlzXqiLUmikONMD7GoD8	false	binding-associated region:1522-1673("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5M9Q1	uniprotkb:P14335-PRO_0000037713	intact:EBI-11423380|uniprotkb:Q9H4Q7|uniprotkb:Q3MIV1|ensembl:ENSP00000345716	intact:EBI-11422701	psi-mi:nkapl_human(display_long)|uniprotkb:NKAPL(gene name)|psi-mi:NKAPL(display_short)|uniprotkb:C6orf194(gene name synonym)	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423386|imex:IM-24738-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007532.1|ensembl:ENSG00000189134(gene)|ensembl:ENST00000343684(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030154"(cell differentiation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466	intact:EBI-11462784(chain-parent)	psi-mi:"MI:0471"(mint)	-	chain-seq-start:2529|chain-seq-end:3433	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:KRRFts9hZmrSKsB64zClwAjG2gA9606	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	intact-crc:6483DD39EAD1F2EB|rigid:SZsKjBp46AkojORxQwnzg3QBeNc	false	-	binding-associated region:1-905("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13232	uniprotkb:Q9E7P0	intact:EBI-713684|uniprotkb:Q9BWH4|ensembl:ENSP00000219302	intact:EBI-11361108	psi-mi:ndk3_human(display_long)|uniprotkb:Nucleoside diphosphate kinase C(gene name synonym)|uniprotkb:nm23-H3(gene name synonym)|uniprotkb:DR-nm23(gene name synonym)|uniprotkb:NME3(gene name)|psi-mi:NME3(display_short)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423394|imex:IM-24738-102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103024(gene)|ensembl:ENST00000219302(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q13232|rcsb pdb:1ZS6|reactome:R-HSA-499943|refseq:NP_002504.2|dip:DIP-49960N	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:/egrHNJSuCILf6NdwwchG9rUGqI9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:4F3159ABD0C6694F|rigid:17iKKvA6hw7MwYRqj9JkyOiag/M	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q13232	intact:EBI-11422582	intact:EBI-713684|uniprotkb:Q9BWH4|ensembl:ENSP00000219302	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:ndk3_human(display_long)|uniprotkb:Nucleoside diphosphate kinase C(gene name synonym)|uniprotkb:nm23-H3(gene name synonym)|uniprotkb:DR-nm23(gene name synonym)|uniprotkb:NME3(gene name)|psi-mi:NME3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423402|imex:IM-24738-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSG00000103024(gene)|ensembl:ENST00000219302(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q13232|rcsb pdb:1ZS6|reactome:R-HSA-499943|refseq:NP_002504.2|dip:DIP-49960N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:/egrHNJSuCILf6NdwwchG9rUGqI9606	intact-crc:20691A24AC70713F|rigid:bGQLFZN1jQCx9uxZY/O+izG+dxU	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:P11940	intact:EBI-11422582	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423450|imex:IM-24738-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:ED8288E068AAF042|rigid:Tb/HnmMtLXQ66NA6NyPGyypEz+4	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q96CV9	intact:EBI-11422582	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423434|imex:IM-24738-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2018/04/06	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:508874B35DEB95B2|rigid:9F0wZX7FwerYQIAY6jnVFqsf2ss	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QXP6	uniprotkb:Q96CV9	intact:EBI-11422617	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:q8qxp6_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11072(japanese encephalitis virus)|taxid:11072(Japanese encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423426|imex:IM-24738-106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2018/04/06	rogid:j+swWwyqabf1+ccBM10YutAzZNg11072	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:6F6E21CDCD3AD7FB|rigid:JPQ533C1ojs430u3h2zQ4mBNQ4U	false	binding-associated region:1521-1672("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q9Y3T9	intact:EBI-11422701	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423418|imex:IM-24738-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	intact-crc:B436C469174BBD92|rigid:A2uw5Urwlp39rmxgQVhJIsPe0Bg	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:P11940	intact:EBI-11361108	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423442|imex:IM-24738-108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:6CA0E68FB5292FA7|rigid:bOJZsMAIj/dShntpDRkmaMQXcNU	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q5VU43	intact:EBI-11422640	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423466|imex:IM-24738-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2018/04/06	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:F4D11EFEB51E177E|rigid:J/b55PFEj4k9/HeUmmPzt3Z/8PY	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q8IXK0	intact:EBI-11422591	intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40	psi-mi:polg_alkv(display_long)	psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423474|imex:IM-24738-112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:7si/KU2tHoxviuCr70ncQERDWmY9606	intact-crc:6B2B2D2EE5A2BDA3|rigid:5xBCWpxm3oIffiqeJkVfT5+uXfg	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q8IXK0	intact:EBI-11422640	intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423482|imex:IM-24738-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:7si/KU2tHoxviuCr70ncQERDWmY9606	intact-crc:BC81AF5BBD675A94|rigid:b38CWu51B5J7dV25/bA45Bci/HI	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q5VU43	intact:EBI-11422591	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:polg_alkv(display_long)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423458|imex:IM-24738-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2018/04/06	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:F67A6FB7D0771385|rigid:NivfU5KJWFICYzKWyOSxlhdge4M	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q9Y6X2	intact:EBI-11422701	intact:EBI-2803703|uniprotkb:Q9UFI3|intact:EBI-28970301|ensembl:ENSP00000376765	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:pias3_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:PIAS3(gene name)|psi-mi:PIAS3(display_short)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423514|imex:IM-24738-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSP00000376765|ensembl:ENSG00000131788(gene)|ensembl:ENST00000393045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:Q9Y6X2|rcsb pdb:4MVT|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|go:"GO:0016925"(protein sumoylation)|refseq:NP_006090.2|dip:DIP-5969N	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:uAxtGVgFcpm5yJL1rul8vVciHZA9606	intact-crc:DB7C706ACD4D99C6|rigid:s+s9Igeh6n56LLeJHSdHArLWYwI	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9Y6X2	intact:EBI-11422591	intact:EBI-2803703|uniprotkb:Q9UFI3|intact:EBI-28970301|ensembl:ENSP00000376765	psi-mi:polg_alkv(display_long)	psi-mi:pias3_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:PIAS3(gene name)|psi-mi:PIAS3(display_short)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423506|imex:IM-24738-116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSP00000376765|ensembl:ENSG00000131788(gene)|ensembl:ENST00000393045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:Q9Y6X2|rcsb pdb:4MVT|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|go:"GO:0016925"(protein sumoylation)|refseq:NP_006090.2|dip:DIP-5969N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:uAxtGVgFcpm5yJL1rul8vVciHZA9606	intact-crc:F2BACD981523AB2C|rigid:FKWOhwE6iL6VvaKqHTWPwxxlbmg	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q6NSJ2	intact:EBI-11422582	intact:EBI-6148204|uniprotkb:Q8N7Z4|ensembl:ENSP00000292140	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:phlb3_human(display_long)|uniprotkb:PHLDB3(gene name)|psi-mi:PHLDB3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423498|imex:IM-24738-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_942147.3|ensembl:ENSG00000176531(gene)|ensembl:ENST00000292140(transcript)|go:"GO:0019899"(enzyme binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:mHR2QwOa65vWru5ZUAnRSjMU8lU9606	intact-crc:34D0B45B3A30F2C6|rigid:KiZK8GYdaqp4iLZVeTyYrc/X/eY	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:Q6NSJ2	intact:EBI-11361108	intact:EBI-6148204|uniprotkb:Q8N7Z4|ensembl:ENSP00000292140	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:phlb3_human(display_long)|uniprotkb:PHLDB3(gene name)|psi-mi:PHLDB3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423490|imex:IM-24738-114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_942147.3|ensembl:ENSG00000176531(gene)|ensembl:ENST00000292140(transcript)|go:"GO:0019899"(enzyme binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:mHR2QwOa65vWru5ZUAnRSjMU8lU9606	intact-crc:F85728D9631BA86C|rigid:dGnFQKaFg1bbcJ9uU5sRsiLSgcI	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:O75569	intact:EBI-11361108	intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423546|imex:IM-24738-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:tZfziopZlC+1d3De97G3kDY+Tog9606	intact-crc:256AC86ED3A28E49|rigid:YNkGFePzj2ceL1yByNp5rx3gfC0	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q5VV67	intact:EBI-11422701	intact:EBI-1045850|uniprotkb:Q5VV66|uniprotkb:Q6P3U5|uniprotkb:Q6P3W1|uniprotkb:Q76N31|uniprotkb:Q9BUJ3|uniprotkb:Q9BZE5|uniprotkb:Q9Y4E0|intact:EBI-28968769|ensembl:ENSP00000278070	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:pprc1_human(display_long)|uniprotkb:PGC-1-related coactivator(gene name synonym)|uniprotkb:PPRC1(gene name)|psi-mi:PPRC1(display_short)|uniprotkb:KIAA0595(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423538|imex:IM-24738-120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSP00000278070|refseq:NP_055877.3|ensembl:ENSG00000148840(gene)|ensembl:ENST00000278070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034597|interpro:IPR034605|interpro:IPR034834|interpro:IPR035979|reactome:R-HSA-2151201|refseq:NP_001275656.1|refseq:NP_001275657.1	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:CzoJyQC7ZylKapYmIL3Ik5IxhBk9606	intact-crc:7DE928C132B8191A|rigid:ZgyFZwoe9nIviC/aL1fx+vy6w6g	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9H7J1	intact:EBI-11422591	intact:EBI-5550063|uniprotkb:D3DS47|ensembl:ENSP00000408288	psi-mi:polg_alkv(display_long)	psi-mi:ppr3e_human(display_long)|uniprotkb:PPP1R3E(gene name)|psi-mi:PPP1R3E(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423530|imex:IM-24738-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001263247.1|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR038175|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0042587"(glycogen granule)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0050196"([phosphorylase] phosphatase activity)|ensembl:ENSG00000235194(gene)|ensembl:ENST00000452015(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:mvnxVQqt2eEvHfHkspYu80uZcb89606	intact-crc:39186C47907370CD|rigid:Becqv6coPypcTFpOPoGX5mJTPnc	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:O14744	intact:EBI-11361108	intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423554|imex:IM-24738-122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606	intact-crc:23A6D20488ED0268|rigid:Yx5q0QEkzz+YU41ynmxbvDZS6bc	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9E7P0	uniprotkb:P13797	intact:EBI-11361108	intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423522|imex:IM-24738-118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606	intact-crc:21F93A5B01EAAE82|rigid:ghLs9QqDnhBiJ/ma4ahmNyMQdpE	false	binding-associated region:1491-1643("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:Q96EQ8	intact:EBI-11422668	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423586|imex:IM-24738-126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:C9F3B902963540CE|rigid:9pVh1X1g3rnUTjcDB+3bsj5nhdA	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q9NVW2	intact:EBI-11422701	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423578|imex:IM-24738-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	intact-crc:A7FE63B869FF14AA|rigid:P0wc2c+99DD1H/mQLdBjwzhnhUs	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q02833	intact:EBI-11422591	intact:EBI-929013|ensembl:ENSP00000380713|ensembl:ENSP00000479652|uniprotkb:Q3KP42|intact:EBI-11052282|uniprotkb:G5E9N9|uniprotkb:Q3KP41	psi-mi:polg_alkv(display_long)	psi-mi:rasf7_human(display_long)|uniprotkb:RASSF7(gene name)|psi-mi:RASSF7(display_short)|uniprotkb:C11orf13(gene name synonym)|uniprotkb:HRC1(gene name synonym)|uniprotkb:HRAS1-related cluster protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423570|imex:IM-24738-124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000099849(gene)|ensembl:ENSG00000273859(gene)|ensembl:ENST00000397583(transcript)|ensembl:ENST00000622905(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0034451"(centriolar satellite)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR000159(Ras-association)|interpro:IPR029071|interpro:IPR033593|interpro:IPR033631|refseq:NP_001137465.1|refseq:NP_001137466.1|refseq:NP_003466.1|refseq:XP_016873850.1|refseq:XP_016873851.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:p1j9prChoZIecLZDG02TGJ0Z76I9606	intact-crc:8F62B50BD4470D91|rigid:mjJGHrxjRD7UeWvsnZ49vAhdA+s	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:Q9UNM6	intact:EBI-11422582	intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423562|imex:IM-24738-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:iOxE62MMeGx+aqsrir/LukJqeho9606	intact-crc:9CAB16B213FA3F2A|rigid:GEeHFszBWER2mYmZ/KlWFpMq8Vo	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QXP6	uniprotkb:P60866	intact:EBI-11422617	intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670	psi-mi:q8qxp6_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11072(japanese encephalitis virus)|taxid:11072(Japanese encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423618|imex:IM-24738-130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:j+swWwyqabf1+ccBM10YutAzZNg11072	rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606	intact-crc:591D2FF92E2C9939|rigid:j3jw9Uz2RXhKwtaBhmCb1BzIX9c	false	binding-associated region:1521-1672("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q96EQ8	intact:EBI-11422640	intact:EBI-2339208|uniprotkb:Q9NX39|ensembl:ENSP00000217740	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rn125_human(display_long)|uniprotkb:RNF125(gene name)|psi-mi:RNF125(display_short)|uniprotkb:RING finger protein 125(gene name synonym)|uniprotkb:T-cell RING activation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423594|imex:IM-24738-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_060301.2|dip:DIP-52778N|ensembl:ENSG00000101695(gene)|ensembl:ENST00000217740(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR034734|rcsb pdb:5DKA|reactome:R-HSA-936440	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:GvKsp1UoNks9+nDgJ/djM7D3VFc9606	intact-crc:F7386DD4A66AF939|rigid:efVARqO4CDA61JdPawsuYnz7KUo	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9H814	intact:EBI-11422591	intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540	psi-mi:polg_alkv(display_long)	psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423602|imex:IM-24738-128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606	intact-crc:D16F19A982021029|rigid:h+ECIHat8i2sAAYWf7sRJmVQWrk	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q9H814	intact:EBI-11422640	intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423610|imex:IM-24738-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606	intact-crc:86B9EFFA86FBB87B|rigid:SIYw3e1h8id2DoNgrhskrtVS05I	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q14160	intact:EBI-11422640	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423634|imex:IM-24738-132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	intact-crc:EFA75A3A8F2B48AF|rigid:HFWKlzeB6YcURLPn1uoJCUnHeXU	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96GD3	uniprotkb:Q9E7P0	intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8	intact:EBI-11361108	psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423626|imex:IM-24738-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:e39O++wYwPAUlKUeNfRurqnXbz09606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:894ACF797CC37BA0|rigid:HdXhUqZ6Ck7cmQjtKZ4lQBy5Nkg	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:O43255	intact:EBI-11422668	intact:EBI-948141|uniprotkb:O43270|ensembl:ENSP00000322457	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:siah2_human(display_long)|uniprotkb:Seven in absentia homolog 2(gene name synonym)|uniprotkb:SIAH2(gene name)|psi-mi:SIAH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SIAH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423650|imex:IM-24738-134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_005058.3|dip:DIP-41874N|ensembl:ENSG00000181788(gene)|ensembl:ENST00000312960(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|rcsb pdb:5H9M|reactome:R-HSA-373752|reactome:R-HSA-5689880|reactome:R-HSA-977225|reactome:R-HSA-983168	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:1AUfjiUQFAEsOkxiSwdWZX4aPbY9606	intact-crc:B79ED5528E1D62C7|rigid:KS4a0B5WPDiLiAPYHa0MNJBK4M0	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q14160	intact:EBI-11422591	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:polg_alkv(display_long)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423642|imex:IM-24738-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	intact-crc:ED0C2B73EA424C54|rigid:2N8FtmqnJXxRogdkDCiDWLvlqiw	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q92804	intact:EBI-11422591	intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040	psi-mi:polg_alkv(display_long)	psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423674|imex:IM-24738-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606	intact-crc:62D84644F6C48F96|rigid:5B+K1QVRlR3513tOZyDQS6lqQ0k	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q92804	intact:EBI-11422640	intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423666|imex:IM-24738-136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606	intact-crc:350EB017F23D27C4|rigid:45rWlz6wqNZO9gp8P0RcY2lXvNA	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q12824	intact:EBI-11422640	intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423658|imex:IM-24738-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:4613D3E6E91B51FB|rigid:vIa8TnoRtYZjdwAF7thkOeVTFfw	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:Q92804	intact:EBI-11422668	intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423682|imex:IM-24738-138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606	intact-crc:0BC564C1C2629E33|rigid:WMRA2iNic63TxFC74jNAjQwL+YY	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q8N5G2	intact:EBI-11422591	intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463	psi-mi:polg_alkv(display_long)	psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423711|imex:IM-24738-140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178(gene)|ensembl:ENST00000374343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-HSA-8980692|reactome:R-HSA-9013106	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606	intact-crc:820966C7CB429F50|rigid:/Gu9iPVmyPqv7nnAs3BDfTIFpno	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15025	uniprotkb:Q9E7P0	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-11361108	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423719|imex:IM-24738-141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:ECED15C2113AA5C4|rigid:mgsvvr1LSLLE+47mWSFK9xIFgsk	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037713	uniprotkb:Q9UIK5	intact:EBI-11422701	intact:EBI-11423693|ensembl:ENSP00000272771|uniprotkb:Q53H90|uniprotkb:Q4ZFW4|uniprotkb:Q2FA44|uniprotkb:Q9UK65|uniprotkb:Q9NR15|uniprotkb:Q53RE1|uniprotkb:Q8N2R5|uniprotkb:Q9P2Y9|uniprotkb:Q9NSS5	psi-mi:p14335-pro_0000037713(display_long)	psi-mi:teff2_human(display_long)|uniprotkb:TMEFF2(gene name)|psi-mi:TMEFF2(display_short)|uniprotkb:HPP1(gene name synonym)|uniprotkb:Hyperplastic polyposis protein 1(gene name synonym)|uniprotkb:TENB2(gene name synonym)|uniprotkb:TPEF(gene name synonym)|uniprotkb:Transmembrane protein with EGF-like and two follistatin-like domains(gene name synonym)|uniprotkb:UNQ178/PRO204(orf name)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423690|imex:IM-24738-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSG00000144339(gene)|ensembl:ENST00000272771(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0051497"(negative regulation of stress fiber assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR036058|rcsb pdb:2FMW|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|refseq:NP_001292063.1|refseq:NP_001292074.1|refseq:NP_057276.2	psi-mi:"MI:0471"(mint)	chain-seq-start:2529|chain-seq-end:3433	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:BQ1vxZUGS4JNLjaS9mjGnncec3s11078	rogid:cjznO3tchWAGUCRwK+0QEyj1cgA9606	intact-crc:D731EE8F333E570D|rigid:4zJdwkKGJL+uleX1FOXli8unxCY	false	binding-associated region:1-905("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:O75674	intact:EBI-11422668	intact:EBI-712991|intact:EBI-28969677|ensembl:ENSP00000460823|uniprotkb:Q53G06|uniprotkb:Q8N749|uniprotkb:B7Z9E2	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:tm1l1_human(display_long)|uniprotkb:Target of Myb-like protein 1(gene name synonym)|uniprotkb:Src-activating and signaling molecule protein(gene name synonym)|uniprotkb:TOM1L1(gene name)|psi-mi:TOM1L1(display_short)|uniprotkb:SRCASM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423727|imex:IM-24738-142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	ensembl:ENSG00000141198(gene)|ensembl:ENST00000575882(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR027428|mint:O75674|rcsb pdb:3RRU|interpro:IPR038425|refseq:NP_005477.2|ensembl:ENST00000348161|ensembl:ENSP00000343901|ensembl:ENST00000536554|ensembl:ENSP00000443099|ensembl:ENST00000570371|ensembl:ENSP00000458553|ensembl:ENST00000575333|ensembl:ENSP00000458918|ensembl:ENSP00000460823|refseq:NP_001308102.1|refseq:NP_001308103.1|refseq:NP_001308104.1|refseq:NP_001308105.1|refseq:XP_016879491.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:JQewIcPaPAlc2CknMG3p45OWbhI9606	intact-crc:212C0960A6F65585|rigid:SUZ958pN22idcBRAWJyKempTggo	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:O75674	intact:EBI-11422640	intact:EBI-712991|intact:EBI-28969677|ensembl:ENSP00000460823|uniprotkb:Q53G06|uniprotkb:Q8N749|uniprotkb:B7Z9E2	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:tm1l1_human(display_long)|uniprotkb:Target of Myb-like protein 1(gene name synonym)|uniprotkb:Src-activating and signaling molecule protein(gene name synonym)|uniprotkb:TOM1L1(gene name)|psi-mi:TOM1L1(display_short)|uniprotkb:SRCASM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423735|imex:IM-24738-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000141198(gene)|ensembl:ENST00000575882(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR027428|mint:O75674|rcsb pdb:3RRU|interpro:IPR038425|refseq:NP_005477.2|ensembl:ENST00000348161|ensembl:ENSP00000343901|ensembl:ENST00000536554|ensembl:ENSP00000443099|ensembl:ENST00000570371|ensembl:ENSP00000458553|ensembl:ENST00000575333|ensembl:ENSP00000458918|ensembl:ENSP00000460823|refseq:NP_001308102.1|refseq:NP_001308103.1|refseq:NP_001308104.1|refseq:NP_001308105.1|refseq:XP_016879491.1	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:JQewIcPaPAlc2CknMG3p45OWbhI9606	intact-crc:21E3B31300A8BCD0|rigid:rQusD6k28+QZxBR9HVajVtX57ZM	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14335-PRO_0000037710	uniprotkb:O94842	intact:EBI-11422582	intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423743|imex:IM-24738-144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11462784(chain-parent)	ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1	psi-mi:"MI:0471"(mint)	chain-seq-start:1506|chain-seq-end:2124	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	intact-crc:9CF2DBFA8641B9DD|rigid:aQZ3CuCUjccJABN10Lpp8NvRklA	false	binding-associated region:1-619("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P19474	intact:EBI-11422591	intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436	psi-mi:polg_alkv(display_long)	psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423783|imex:IM-24738-149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606	intact-crc:98C68D6FE664F7DE|rigid:S9c7GNOSxm+pOgHjC6sTlhU2PIo	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14545	uniprotkb:Q9E7P0	intact:EBI-1396921|uniprotkb:B4DI89|uniprotkb:A8K5L6|intact:EBI-28969419|ensembl:ENSP00000257604|ensembl:ENSP00000396526	intact:EBI-11361108	psi-mi:trad1_human(display_long)|uniprotkb:TRAFD1(gene name)|psi-mi:TRAFD1(display_short)|uniprotkb:FLN29(gene name synonym)|uniprotkb:Protein FLN29(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423775|imex:IM-24738-148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000257604|ensembl:ENSP00000396526|ensembl:ENST00000552890|ensembl:ENSP00000447340|refseq:NP_001137378.1|refseq:NP_006691.1|ensembl:ENSG00000135148(gene)|ensembl:ENST00000257604(transcript)|ensembl:ENST00000412615(transcript)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2D9K	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:hDY19qxNvWdsjDOoUEpuYfe0cdA9606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:72E0CFA82006DDEB|rigid:d5ymbGkavuvTElQ/gbJMFZl40OU	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BUZ4	uniprotkb:Q5ERI7	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-11422733	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:q5eri7_wnv(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11082(wnv)|taxid:11082("West Nile virus (WNV)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423767|imex:IM-24738-147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:sncTVhdrW1RxLUewzsHEJmMs6WI11082	intact-crc:D952B925517D8C09|rigid:uj2KI2hOy96MGmphk6aK3j/bNyg	false	-	binding-associated region:1522-1673("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BUZ4	uniprotkb:Q9E7P0	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-11361108	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:q9e7p0_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11060(dengue virus 2)|taxid:11060(Dengue virus 2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423751|imex:IM-24738-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1	interpro:IPR038688|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR026470|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR027287|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026490|interpro:IPR027417|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR029063|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:2Zey6eP/I+SVreSaHlUW1yusFcE11060	intact-crc:91D89FCDDC5632BA|rigid:tw4bcKSPR+/unTxh0B1m2tAQH4M	false	-	binding-associated region:1491-1643("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BUZ4	uniprotkb:P14335-PRO_0000037710	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-11422582	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:p14335-pro_0000037710(display_long)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11078(strain mrm61c)|taxid:11078(Kunjin virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423759|imex:IM-24738-146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1	intact:EBI-11462784(chain-parent)	psi-mi:"MI:0471"(mint)	-	chain-seq-start:1506|chain-seq-end:2124	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:lD2M5XF6phcyblpcVkxOmMeTE+k11078	intact-crc:60CF8E1C239D8D99|rigid:9MecOp57J51JZeoZZxUWZuYR3OU	false	-	binding-associated region:1-619("MI:0117")	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P19474	intact:EBI-11422640	intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423791|imex:IM-24738-150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606	intact-crc:9A6DFC26830DF325|rigid:eL6GTdYODnyl5LW5iNs/+ljlVns	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:O14530	intact:EBI-11422591	intact:EBI-707554|uniprotkb:D3DVI4|uniprotkb:Q53RV8|uniprotkb:Q6NSF5|uniprotkb:Q9BRU6|uniprotkb:B2R9G8|uniprotkb:Q53HG4|uniprotkb:Q8TB70|ensembl:ENSP00000264255	psi-mi:polg_alkv(display_long)	psi-mi:txnd9_human(display_long)|uniprotkb:Protein 1-4(gene name synonym)|uniprotkb:ATP-binding protein associated with cell differentiation(gene name synonym)|uniprotkb:TXNDC9(gene name)|psi-mi:TXNDC9(display_short)|uniprotkb:APACD(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423807|imex:IM-24738-152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_005774.2|ensembl:ENSG00000115514(gene)|ensembl:ENST00000264255(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:juH2+xAayd3ASfZg1RBQ30ewQ8k9606	intact-crc:8F88E9EA44D13306|rigid:GKwLQuMRnWp230vWTz5OgWo1mPY	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:O14530	intact:EBI-11422640	intact:EBI-707554|uniprotkb:D3DVI4|uniprotkb:Q53RV8|uniprotkb:Q6NSF5|uniprotkb:Q9BRU6|uniprotkb:B2R9G8|uniprotkb:Q53HG4|uniprotkb:Q8TB70|ensembl:ENSP00000264255	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:txnd9_human(display_long)|uniprotkb:Protein 1-4(gene name synonym)|uniprotkb:ATP-binding protein associated with cell differentiation(gene name synonym)|uniprotkb:TXNDC9(gene name)|psi-mi:TXNDC9(display_short)|uniprotkb:APACD(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423799|imex:IM-24738-151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_005774.2|ensembl:ENSG00000115514(gene)|ensembl:ENST00000264255(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:juH2+xAayd3ASfZg1RBQ30ewQ8k9606	intact-crc:8D2398A321B837FD|rigid:R21JaI7YSlbF8C9grUodqiICCwI	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P08670	intact:EBI-11422591	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007	psi-mi:polg_alkv(display_long)	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423823|imex:IM-24738-154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	intact-crc:55E7BFD8DCA71C87|rigid:dk6oElb6ldbRnCjS5/Airf2UYe4	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P29597	intact:EBI-11422640	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423815|imex:IM-24738-153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	intact-crc:130C9728BCFE4464|rigid:c/RwLnawp/BY57mYYQeWL5AEgtA	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:P08670	intact:EBI-11422640	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423831|imex:IM-24738-155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	intact-crc:574CCE91B9CE187C|rigid:LBqsGkr+HpGrwxhLOk3rgEUpRFc	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q13105	intact:EBI-11422591	intact:EBI-372156|uniprotkb:A0AV07|uniprotkb:Q15932|uniprotkb:Q5JYB2|uniprotkb:B4DXB4|uniprotkb:F5H411|uniprotkb:Q9NUC9|uniprotkb:B7ZLQ9|ensembl:ENSP00000364895	psi-mi:polg_alkv(display_long)	psi-mi:zbt17_human(display_long)|uniprotkb:ZBTB17(gene name)|psi-mi:ZBTB17(display_short)|uniprotkb:MIZ1(gene name synonym)|uniprotkb:Zinc finger protein 60(gene name synonym)|uniprotkb:Zinc finger protein 151(gene name synonym)|uniprotkb:Myc-interacting zinc finger protein 1(gene name synonym)|uniprotkb:ZNF151(gene name synonym)|uniprotkb:ZNF60(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423863|imex:IM-24738-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:XP_011540390.1|refseq:NP_001229813.1|refseq:NP_003434.2|refseq:NP_001274532.1|ensembl:ENSG00000116809(gene)|ensembl:ENST00000375743(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q13105|rcsb pdb:2LVR|rcsb pdb:2LVT|rcsb pdb:2LVU|rcsb pdb:2M0D|rcsb pdb:2M0E|rcsb pdb:2M0F|rcsb pdb:2N25|rcsb pdb:2N26|rcsb pdb:2Q81|rcsb pdb:3M52|rcsb pdb:4U2M|rcsb pdb:4U2N|rcsb pdb:5ION|rcsb pdb:7MC1|rcsb pdb:7MC2|rcsb pdb:7MC3|reactome:R-HSA-381038|dip:DIP-5968N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:UnpKBOl8g2pZRvmUJDyE3fN7VCg9606	intact-crc:4EC0463E023F02BB|rigid:YMLzBE6/kSk8vuYx1JA9iWU7g58	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q9H270	intact:EBI-11422640	intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423855|imex:IM-24738-158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606	intact-crc:5A6AE8C99F54B03B|rigid:OsbkPWpVWG6afPt5d3gzSyVHYCw	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91NH1	uniprotkb:Q9H270	intact:EBI-11422668	intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680	psi-mi:q91nh1_9flav(display_long)|uniprotkb:Non-structural protein 5(gene name synonym)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11053(dengue virus 1)|taxid:11053(Dengue virus 1)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423847|imex:IM-24738-157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR037172|interpro:IPR043502|interpro:IPR043504	refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:Xbmu1iOGcZw1RGMD1LatUirjNVQ11053	rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606	intact-crc:64A13C1FAF0B09CC|rigid:/50QHDTKOrnmjhJQmkObFXsn6XA	false	binding-associated region:2743-3388("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:Q9H270	intact:EBI-11422591	intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680	psi-mi:polg_alkv(display_long)	psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423839|imex:IM-24738-156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606	intact-crc:0DBC1E9A9BAD1869|rigid:/GTpiyXw2oZYN12yGled54CKH10	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q91B85	uniprotkb:P52742	intact:EBI-11422591	intact:EBI-7101455|ensembl:ENSP00000321406|uniprotkb:Q8N1I7|uniprotkb:B4DHH9|uniprotkb:I3L0B3|uniprotkb:Q5U5L3|intact:MINT-8247363|uniprotkb:E9PEV2|uniprotkb:F5GYY9	psi-mi:polg_alkv(display_long)	psi-mi:zn135_human(display_long)|uniprotkb:ZNF135(gene name)|psi-mi:ZNF135(display_short)|uniprotkb:ZNF61(gene name synonym)|uniprotkb:ZNF78L1(gene name synonym)|uniprotkb:Zinc finger protein 61(gene name synonym)|uniprotkb:Zinc finger protein 78-like 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:172148(alkhumra hemorrhagic fever virus)|taxid:172148(Alkhumra hemorrhagic fever virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423887|imex:IM-24738-162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|refseq:NP_722551.1|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	ensembl:ENSG00000176293(gene)|ensembl:ENST00000313434(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_003427.3|refseq:NP_001158002.1|refseq:NP_001158001.1|refseq:NP_009065.1|refseq:XP_016882729.1|refseq:NP_001276330.1|refseq:NP_001276331.1|refseq:XP_006723425.1|refseq:XP_006723426.1	psi-mi:"MI:0471"(mint)	-	comment:mint|comment:homomint	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:OmpQxjuNkMEbqTAMU+xFpWbevkA172148	rogid:Ctyy4KlO7qrOah4lRPm55fbcQFI9606	intact-crc:E9FC59BE9161FB8F|rigid:w+Di1pCgPjVSpPvnFK7HJUdCZyU	false	binding-associated region:2767-3410("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q13105	intact:EBI-11422640	intact:EBI-372156|uniprotkb:A0AV07|uniprotkb:Q15932|uniprotkb:Q5JYB2|uniprotkb:B4DXB4|uniprotkb:F5H411|uniprotkb:Q9NUC9|uniprotkb:B7ZLQ9|ensembl:ENSP00000364895	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:zbt17_human(display_long)|uniprotkb:ZBTB17(gene name)|psi-mi:ZBTB17(display_short)|uniprotkb:MIZ1(gene name synonym)|uniprotkb:Zinc finger protein 60(gene name synonym)|uniprotkb:Zinc finger protein 151(gene name synonym)|uniprotkb:Myc-interacting zinc finger protein 1(gene name synonym)|uniprotkb:ZNF151(gene name synonym)|uniprotkb:ZNF60(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423871|imex:IM-24738-160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:XP_011540390.1|refseq:NP_001229813.1|refseq:NP_003434.2|refseq:NP_001274532.1|ensembl:ENSG00000116809(gene)|ensembl:ENST00000375743(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q13105|rcsb pdb:2LVR|rcsb pdb:2LVT|rcsb pdb:2LVU|rcsb pdb:2M0D|rcsb pdb:2M0E|rcsb pdb:2M0F|rcsb pdb:2N25|rcsb pdb:2N26|rcsb pdb:2Q81|rcsb pdb:3M52|rcsb pdb:4U2M|rcsb pdb:4U2N|rcsb pdb:5ION|rcsb pdb:7MC1|rcsb pdb:7MC2|rcsb pdb:7MC3|reactome:R-HSA-381038|dip:DIP-5968N	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:UnpKBOl8g2pZRvmUJDyE3fN7VCg9606	intact-crc:4C6B377767560640|rigid:fysobAfjXXuxBMhlmO5rqmZpO+o	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q88489	uniprotkb:Q9NP64	intact:EBI-11422640	intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38	psi-mi:q88489_9flav(display_long)|uniprotkb:Envelope protein E(gene name synonym)|uniprotkb:Flavivirin protease NS2B regulatory subunit(gene name synonym)|uniprotkb:Flavivirin protease NS3 catalytic subunit(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:Matrix protein(gene name synonym)|uniprotkb:Non-structural protein 1(gene name synonym)|uniprotkb:Non-structural protein 2A(gene name synonym)|uniprotkb:Non-structural protein 2B(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Peptide 2k(gene name synonym)|uniprotkb:Peptide pr(gene name synonym)|uniprotkb:Protein prM(gene name synonym)|uniprotkb:RNA-directed RNA polymerase NS5(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:Serine protease subunit NS2B(gene name synonym)|uniprotkb:Small envelope protein M(gene name synonym)	psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Le et al. (2010)	pubmed:22014111|imex:IM-24738	taxid:11084(tick-borne encephalitis virus)|taxid:11084(Tick-borne encephalitis virus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11423879|imex:IM-24738-161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038688|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR026470|interpro:IPR026490|interpro:IPR027287|interpro:IPR027417|interpro:IPR029063|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055036"(virion membrane)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|interpro:IPR036253|interpro:IPR043502	refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO	psi-mi:"MI:0471"(mint)	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/05	2015/11/24	rogid:kwoKvCg+BfR++Biz0fpQsb2fT8Y11084	rogid:e71wAulRWX6cM59s3g8R42PWXeU9606	intact-crc:8683187FF4783601|rigid:GVn3LEfDzbFQLQqDOV5IJRm37MQ	false	binding-associated region:2765-3408("MI:0117")	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)