#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8ZNG2 uniprotkb:P22059 intact:EBI-10690213|ensemblbacteria:AAL21188 intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847 psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name) psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Auweter et al. (2012) pubmed:21988961|imex:IM-25856 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10710869|imex:IM-25856-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_461229.3|ensemblbacteria:AAL21188(transcript)|ensemblbacteria:STM2287(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5HAF|rcsb pdb:5UBW|dip:DIP-60877N refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/03/18 2015/03/27 rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287 rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606 rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU false ha tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8ZNG2 uniprotkb:P22059 intact:EBI-10690213|ensemblbacteria:AAL21188 intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847 psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name) psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Auweter et al. (2012) pubmed:21988961|imex:IM-25856 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10710881|imex:IM-25856-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_461229.3|ensemblbacteria:AAL21188(transcript)|ensemblbacteria:STM2287(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5HAF|rcsb pdb:5UBW|dip:DIP-60877N refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/03/18 2015/03/27 rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287 rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606 rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8ZNG2 uniprotkb:P22059 intact:EBI-10690213|ensemblbacteria:AAL21188 intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847 psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name) psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Auweter et al. (2012) pubmed:21988961|imex:IM-25856 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10710894|imex:IM-25856-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_461229.3|ensemblbacteria:AAL21188(transcript)|ensemblbacteria:STM2287(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5HAF|rcsb pdb:5UBW|dip:DIP-60877N refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:1C-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/03/18 2015/03/27 rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287 rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606 rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU false ha tag:?-? flag tag:?-?|sufficient binding region:182-415 - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q8ZNG2 uniprotkb:P22059 intact:EBI-10690213|ensemblbacteria:AAL21188 intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847 psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name) psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Auweter et al. (2012) pubmed:21988961|imex:IM-25856 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10710905|imex:IM-25856-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_461229.3|ensemblbacteria:AAL21188(transcript)|ensemblbacteria:STM2287(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5HAF|rcsb pdb:5UBW|dip:DIP-60877N refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:1C-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/03/18 2015/03/27 rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287 rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606 rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU false ha tag:?-? flag tag:?-?|sufficient binding region:182-415 - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)