#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P24386 uniprotkb:Q92696 intact:EBI-2515129|ensembl:ENSP00000350386|uniprotkb:O43732|uniprotkb:A1L4D2 intact:EBI-9104196|uniprotkb:A8K5N2|uniprotkb:D3DS69|ensembl:ENSP00000216840|ensembl:ENSP00000382341|ensembl:ENSP00000494636|ensembl:ENSP00000496595 psi-mi:rae1_human(display_long)|uniprotkb:CHM(gene name)|psi-mi:CHM(display_short)|uniprotkb:REP1(gene name synonym)|uniprotkb:TCD(gene name synonym)|uniprotkb:Rab escort protein 1(gene name synonym)|uniprotkb:TCD protein(gene name synonym)|uniprotkb:Choroideremia protein(gene name synonym) psi-mi:pgta_human(display_long)|uniprotkb:RABGGTA(gene name)|psi-mi:RABGGTA(display_short)|uniprotkb:Geranylgeranyl transferase type II subunit alpha(gene name synonym)|uniprotkb:Rab geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:Rab geranylgeranyltransferase subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Esposito et al. (2011) imex:IM-23969|pubmed:21905166 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10686776|imex:IM-23969-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188419(gene)|ensembl:ENST00000357749(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001738("Rab escort (choroideraemia) protein")|interpro:IPR018203|interpro:IPR036188|reactome:R-HSA-6803205|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0016192"(vesicle-mediated transport)|refseq:NP_001307888.1|refseq:NP_000381.1|refseq:NP_001138886.1 refseq:NP_004572.3|refseq:NP_878256.1|ensembl:ENSG00000100949(gene)|ensembl:ENSG00000285193(gene)|ensembl:ENST00000216840(transcript)|ensembl:ENST00000399409(transcript)|ensembl:ENST00000644383(transcript)|ensembl:ENST00000646658(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|interpro:IPR009087(Rab geranylgeranyltransferase, alpha subunit, insert)|interpro:IPR032675|interpro:IPR032955|interpro:IPR036254|reactome:R-HSA-6803205|reactome:R-HSA-8873719 omim:303100(see-also) - - figure legend:4B|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/03/02 2019/12/13 rogid:lLHJ/D4ljKMp+kSHMHu9RUTdcps9606 rogid:oPWV+8Ppm2LhrEekspnRE/9YSK09606 intact-crc:E668F9E2AC8B63CF|rigid:tW8bhKX5HDa9HP1OR3nLJXu1Ga0 false flag tag:n-n|mutation disrupting interaction:507-507 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)