#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-11295639	uniprotkb:O95644	-	intact:EBI-6907210|uniprotkb:Q12865|uniprotkb:Q15793|uniprotkb:B5B2M4|uniprotkb:B5B2M5|uniprotkb:B5B2M6|uniprotkb:B5B2M7|uniprotkb:B5B2M8|uniprotkb:B5B2M9|uniprotkb:B5B2N1|uniprotkb:Q2M1S3|ensembl:ENSP00000389377	psi-mi:c25_variant_nkx2-3_probe_ promoter region_at rs11190140_location(display_short)|psi-mi:EBI-11295639(display_long)	psi-mi:nfac1_human(display_long)|uniprotkb:NFATC1(gene name)|psi-mi:NFATC1(display_short)|uniprotkb:NFAT2(gene name synonym)|uniprotkb:NFATC(gene name synonym)|uniprotkb:NFAT transcription complex cytosolic component(gene name synonym)	psi-mi:"MI:0096"(pull down)	John et al. (2010)	pubmed:21803625|imex:IM-24605	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11295616|imex:IM-24605-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006153.2|refseq:NP_765975.1|refseq:NP_765976.1|refseq:NP_765977.1|refseq:NP_765978.1|refseq:NP_001265598.1|refseq:NP_001265599.1|refseq:NP_001265601.1|refseq:NP_001265602.1|refseq:NP_001265604.1|dip:DIP-44311N|ensembl:ENSG00000131196(gene)|ensembl:ENST00000427363(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015647(Nuclear factor of activated T-cells 1)|interpro:IPR032397|interpro:IPR037059|mint:O95644|rcsb pdb:1A66|rcsb pdb:1NFA|rcsb pdb:5SVE|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763	-	-	-	figure legend:4|comment:Both methylated and non-methylated oligonucleotides bound to NFAT1.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/08/13	2016/10/13	-	rogid:ighU5P59Gv8yTk6lwwm/Ohy3FdY9606	-	false	biotin tag:?-?|biological feature:7-7	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95644	intact:EBI-11295639	intact:EBI-6907210|uniprotkb:Q12865|uniprotkb:Q15793|uniprotkb:B5B2M4|uniprotkb:B5B2M5|uniprotkb:B5B2M6|uniprotkb:B5B2M7|uniprotkb:B5B2M8|uniprotkb:B5B2M9|uniprotkb:B5B2N1|uniprotkb:Q2M1S3|ensembl:ENSP00000389377	-	psi-mi:nfac1_human(display_long)|uniprotkb:NFATC1(gene name)|psi-mi:NFATC1(display_short)|uniprotkb:NFAT2(gene name synonym)|uniprotkb:NFATC(gene name synonym)|uniprotkb:NFAT transcription complex cytosolic component(gene name synonym)	psi-mi:c25_variant_nkx2-3_probe_ promoter region_at rs11190140_location(display_short)|psi-mi:EBI-11295639(display_long)	psi-mi:"MI:0096"(pull down)	John et al. (2010)	pubmed:21803625|imex:IM-24605	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11295650|imex:IM-24605-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_006153.2|refseq:NP_765975.1|refseq:NP_765976.1|refseq:NP_765977.1|refseq:NP_765978.1|refseq:NP_001265598.1|refseq:NP_001265599.1|refseq:NP_001265601.1|refseq:NP_001265602.1|refseq:NP_001265604.1|dip:DIP-44311N|ensembl:ENSG00000131196(gene)|ensembl:ENST00000427363(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015647(Nuclear factor of activated T-cells 1)|interpro:IPR032397|interpro:IPR037059|mint:O95644|rcsb pdb:1A66|rcsb pdb:1NFA|rcsb pdb:5SVE|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763	-	-	-	-	figure legend:4-1|comment:Both methylated and non-methylated oligonucleotides bound to NFAT1.|disease:The SNP rs11190140 consists of a C to T polymorphism, with the T allele being over-transmitted in IBD populations.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/08/13	2016/10/13	rogid:ighU5P59Gv8yTk6lwwm/Ohy3FdY9606	-	-	false	-	mutation disrupting interaction strength:7-7|biotin tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
ensembl:ENSG00000119919	uniprotkb:O95644	intact:EBI-11295711	intact:EBI-6907210|uniprotkb:Q12865|uniprotkb:Q15793|uniprotkb:B5B2M4|uniprotkb:B5B2M5|uniprotkb:B5B2M6|uniprotkb:B5B2M7|uniprotkb:B5B2M8|uniprotkb:B5B2M9|uniprotkb:B5B2N1|uniprotkb:Q2M1S3|ensembl:ENSP00000389377	uniprotkb:NKX2-3(gene name)|psi-mi:NKX2-3(display_short)|uniprotkb:NKX23(gene name synonym)|uniprotkb:NKX2C(gene name synonym)|ensembl:nkx23_human_gene(shortlabel)|psi-mi:ENSG00000119919(display_long)	psi-mi:nfac1_human(display_long)|uniprotkb:NFATC1(gene name)|psi-mi:NFATC1(display_short)|uniprotkb:NFAT2(gene name synonym)|uniprotkb:NFATC(gene name synonym)|uniprotkb:NFAT transcription complex cytosolic component(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	John et al. (2010)	pubmed:21803625|imex:IM-24605	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11295704|imex:IM-24605-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_660328.2|refseq:XP_011537671.1	refseq:NP_006153.2|refseq:NP_765975.1|refseq:NP_765976.1|refseq:NP_765977.1|refseq:NP_765978.1|refseq:NP_001265598.1|refseq:NP_001265599.1|refseq:NP_001265601.1|refseq:NP_001265602.1|refseq:NP_001265604.1|dip:DIP-44311N|ensembl:ENSG00000131196(gene)|ensembl:ENST00000427363(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015647(Nuclear factor of activated T-cells 1)|interpro:IPR032397|interpro:IPR037059|mint:O95644|rcsb pdb:1A66|rcsb pdb:1NFA|rcsb pdb:5SVE|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763	-	-	-	figure legend:5|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-b-cell)|taxid:9606(Homo sapiens B cell)	-	2015/08/13	2015/10/02	-	rogid:ighU5P59Gv8yTk6lwwm/Ohy3FdY9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)