#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03348 uniprotkb:Q6SSD8 intact:EBI-7845043|intact:MINT-7909008 intact:EBI-10687484 psi-mi:gag_hv1br(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:q6ssd8_chlae(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Klein et al. (2011) imex:IM-24060|pubmed:21543480 taxid:11686(hv1br)|taxid:11686("Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10765680|imex:IM-24060-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0039702"(viral budding via host ESCRT complex)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR014817(Gag protein p6)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR036875 interpro:IPR034348|interpro:IPR017896|interpro:IPR017900|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR027417|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity) - comment:mint - figure legend:3A|comment:"The \"gag-KR9A\" mutant does not bind to ABCE1. It is stated to have mutations of nine basic residues to alanine. However the exact mutations involved are not clearly stated, since figure 1B highlights 14 residues in blue. Reference 26 (Lingappa et al., 2006) only gives mutations for a \"KR10A \" mutant and the stated residues in both publications are not the same."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2015/04/13 2015/04/13 rogid:l6pIf3OAVcmsANexDWcmVjXbjiY11686 rogid:wcpjJZFcDYw5mwRHDVCreZDNhbs9534 rigid:0Ti+iOnNcOkPzH+kGJxHGNUIrb0 false necessary binding region:1-363 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03348 uniprotkb:Q6SSD8 intact:EBI-7845043|intact:MINT-7909008 intact:EBI-10687484 psi-mi:gag_hv1br(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:q6ssd8_chlae(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Klein et al. (2011) imex:IM-24060|pubmed:21543480 taxid:11686(hv1br)|taxid:11686("Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10765696|imex:IM-24060-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0039702"(viral budding via host ESCRT complex)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR014817(Gag protein p6)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR036875 interpro:IPR034348|interpro:IPR017896|interpro:IPR017900|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR027417|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity) - comment:mint - figure legend:5A|comment:Gag was coimmunoprecipitated by anti-ABCE1 from the ∼80S/150S and ∼500S regions of the gradient.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2015/04/13 2015/04/13 rogid:l6pIf3OAVcmsANexDWcmVjXbjiY11686 rogid:wcpjJZFcDYw5mwRHDVCreZDNhbs9534 rigid:0Ti+iOnNcOkPzH+kGJxHGNUIrb0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P03348 uniprotkb:Q6SSD8 intact:EBI-7845043|intact:MINT-7909008 intact:EBI-10687484 psi-mi:gag_hv1br(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:q6ssd8_chlae(display_long) psi-mi:"MI:0020"(transmission electron microscopy) Klein et al. (2011) imex:IM-24060|pubmed:21543480 taxid:11686(hv1br)|taxid:11686("Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10765713|imex:IM-24060-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0039702"(viral budding via host ESCRT complex)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR014817(Gag protein p6)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR036875 interpro:IPR034348|interpro:IPR017896|interpro:IPR017900|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR027417|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity) go:"GO:0005886"(plasma membrane) comment:mint - figure legend:6A|comment:"An assembly-defective provirus HIV-1 Gag-delta-NC-delta-p6 (approximately amino acids 1-377) showed reduced colocalization."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2015/04/13 2015/04/13 rogid:l6pIf3OAVcmsANexDWcmVjXbjiY11686 rogid:wcpjJZFcDYw5mwRHDVCreZDNhbs9534 rigid:0Ti+iOnNcOkPzH+kGJxHGNUIrb0 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)