#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSMUSG00000020383 uniprotkb:O08750 intact:EBI-11424732 intact:EBI-11424699|uniprotkb:Q3ULK2|uniprotkb:Q497U0|ensembl:ENSMUSP00000065363 uniprotkb:Il13(gene name)|psi-mi:Il13(display_short)|uniprotkb:Il-13(gene name synonym)|ensembl:il13_mouse_gene(shortlabel)|psi-mi:ENSMUSG00000020383(display_long) psi-mi:nfil3_mouse(display_long)|uniprotkb:Nfil3(gene name)|psi-mi:Nfil3(display_short)|uniprotkb:E4bp4(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Embryo implantation-related NFIL3/E4BP4-like transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Motomura et al. (2011) pubmed:21460847|imex:IM-24743 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11424729|imex:IM-24743-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_032381.1 refseq:NP_059069.1|refseq:XP_006516940.1|refseq:XP_011242681.1|ensembl:ENSMUSG00000056749(gene)|ensembl:ENSMUST00000071065(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:O08750|refseq:XP_017170907.1 - - - figure legend:7B|comment:There was binding of E4BP4 to the HS1 site in R4 TH1 cells but not in conventional TH1 cells.|causality statement:O08750 increases the expression at protein level of ENSMUSG00000020383|causality statement:O08750 increases the expression at RNA level of ENSMUSG00000020383|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th1)|taxid:10090(Mouse T helper cell Th1) - 2015/10/20 2015/11/25 - rogid:0QQb7os33Vd+ZOrY/eQPqkES7cQ10090 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSMUSG00000016529 uniprotkb:O08750 intact:EBI-6398833 intact:EBI-11424699|uniprotkb:Q3ULK2|uniprotkb:Q497U0|ensembl:ENSMUSP00000065363 psi-mi:il10_mouse_gene(display_short)|psi-mi:ENSMUSG00000016529(display_long) psi-mi:nfil3_mouse(display_long)|uniprotkb:Nfil3(gene name)|psi-mi:Nfil3(display_short)|uniprotkb:E4bp4(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Embryo implantation-related NFIL3/E4BP4-like transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Motomura et al. (2011) pubmed:21460847|imex:IM-24743 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11424751|imex:IM-24743-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_059069.1|refseq:XP_006516940.1|refseq:XP_011242681.1|ensembl:ENSMUSG00000056749(gene)|ensembl:ENSMUST00000071065(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:O08750|refseq:XP_017170907.1 - - - figure legend:7D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th2)|taxid:10090(mouse helper T-lymphocyte Th2) - 2015/10/20 2015/11/25 - rogid:0QQb7os33Vd+ZOrY/eQPqkES7cQ10090 - false sufficient binding region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:O08750 intact:EBI-11424776 intact:EBI-11424699|uniprotkb:Q3ULK2|uniprotkb:Q497U0|ensembl:ENSMUSP00000065363 - psi-mi:nfil3_mouse(display_long)|uniprotkb:Nfil3(gene name)|psi-mi:Nfil3(display_short)|uniprotkb:E4bp4(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Embryo implantation-related NFIL3/E4BP4-like transcription factor(gene name synonym) psi-mi:il13_promoter_probe(display_short)|psi-mi:EBI-11424776(display_long) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Motomura et al. (2011) pubmed:21460847|imex:IM-24743 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11424778|imex:IM-24743-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0319"(deoxyribonucleic acid) refseq:NP_059069.1|refseq:XP_006516940.1|refseq:XP_011242681.1|ensembl:ENSMUSG00000056749(gene)|ensembl:ENSMUST00000071065(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:O08750|refseq:XP_017170907.1 - - - - figure legend:7C|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/10/20 2017/01/18 rogid:0QQb7os33Vd+ZOrY/eQPqkES7cQ10090 - - false - 32p radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)