#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27577 ensembl:ENSMUSG00000039521 intact:EBI-4289053|uniprotkb:Q61403|ensembl:ENSMUSP00000034534 intact:EBI-10899641 psi-mi:ets1_mouse(display_long)|uniprotkb:Ets1(gene name)|psi-mi:Ets1(display_short)|uniprotkb:Ets-1(gene name synonym)|uniprotkb:p54(gene name synonym) uniprotkb:Foxp3(gene name)|psi-mi:Foxp3(display_short)|ensembl:foxp3_mouse_gene(shortlabel)|psi-mi:ENSMUSG00000039521(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Polansky et al. (2010) imex:IM-24451|pubmed:20574810 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10956029|imex:IM-24451-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035938.2|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|rcsb pdb:1K78|rcsb pdb:1K79|rcsb pdb:1K7A|rcsb pdb:1MD0|rcsb pdb:1MDM|rcsb pdb:1R36|rcsb pdb:2JV3|rcsb pdb:2KMD|rcsb pdb:6DA1|rcsb pdb:6DAT|reactome:R-MMU-2559585|go:"GO:0005667"(transcription regulator complex)|ensembl:ENSMUSG00000032035(gene)|ensembl:ENSMUST00000034534(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-41848N refseq:NP_001186276.1|refseq:NP_001186277.1|refseq:NP_473380.1 - - - figure legend:8 B/C|comment:Binding to the TSDR could only be detected in the Treg population, but only in Aza-induced Foxp3+ Tregs, not in TGF-beta-induced Foxp3+ Tregs.|agonist:"5-Aza-2′-deoxycytidine (CHEBI:50131) - a demethylating agent"|causality statement:"CHEBI:50131 increases binding of P27577 to ENSMUSG00000039521"|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell) - 2015/07/13 2015/08/06 rogid:5N3mG6XU77Y0OnF5xeY53Pewa3M10090 - - false - sufficient binding region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr)