#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8TCY5	uniprotkb:Q8TCY5	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Sebag et al. (2009)	imex:IM-24350|pubmed:20371771	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10896289|imex:IM-24350-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	-	-	-	figure legend:Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2015/05/14	2015/07/02	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rigid:9P6ncPUWzfSkbfIiXP0OHZfXXeA	false	cYFP:c-c	nYFP:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96G30	uniprotkb:Q96G30	intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776	intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776	psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym)	psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Sebag et al. (2009)	imex:IM-24350|pubmed:20371771	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10896538|imex:IM-24350-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111	refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111	-	-	-	figure legend:Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2015/05/14	2015/07/06	rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606	rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606	rigid:bdjsOWnHiMV+GIaLcrVPGSGArSI	false	cYFP:c-c	nYFP:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8TCY5	uniprotkb:Q96G30	intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684	intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776	psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym)	psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Sebag et al. (2009)	imex:IM-24350|pubmed:20371771	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10896549|imex:IM-24350-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)	refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111	-	-	-	figure legend:Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2015/05/14	2015/07/02	rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606	rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606	rigid:xXxieZTO35aWb87/6mNpRpTWDPY	false	nYFP:n-n	cYFP:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)