#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96BT7 uniprotkb:Q9UI30 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0018"(two hybrid) Songe-Møller et al. (2010) pubmed:20123966|imex:IM-24185 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825679|imex:IM-24185-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2015/05/29 2015/05/29 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:zRe+PTVMzK+sguzpqtCQmBb5gZ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96BT7 uniprotkb:Q9UI30 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0096"(pull down) Songe-Møller et al. (2010) pubmed:20123966|imex:IM-24185 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825691|imex:IM-24185-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2015/05/29 2015/05/29 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:zRe+PTVMzK+sguzpqtCQmBb5gZ0 false his tag:?-?|sufficient binding region:352-664 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)