#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9ET78	uniprotkb:G1U2U3	intact:EBI-8350389|intact:MINT-4099221|uniprotkb:Q9ET79|uniprotkb:Q3U077|ensembl:ENSMUSP00000017961|ensembl:ENSMUSP00000105052	intact:EBI-10055313|ensembl:ENSOCUP00000023696	psi-mi:jph2_mouse(display_long)|uniprotkb:Jph2(gene name)|psi-mi:Jph2(display_short)|uniprotkb:Jp2(gene name synonym)|uniprotkb:Junctophilin type 2(gene name synonym)	psi-mi:g1u2u3_rabit(display_long)|uniprotkb:TRPC3(gene name)|psi-mi:TRPC3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Woo et al. (2009)	pubmed:19277847|imex:IM-23707	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10055311|imex:IM-23707-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067541.1|refseq:NP_001192005.1|refseq:XP_006500035.1|ensembl:ENSMUSG00000017817(gene)|ensembl:ENSMUST00000017961(transcript)|ensembl:ENSMUST00000109425(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0055024"(regulation of cardiac muscle tissue development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9ET78	ensembl:ENSOCUG00000009487(gene)|ensembl:ENSOCUT00000029876(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0033198"(response to ATP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005459(Transient receptor potential channel 3)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770	-	comment:mint|function:Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development	-	figure legend:1B, 2B and 3B and C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/12	2015/01/12	rogid:vs5IFdM0JlfwvmUcraIjKfxlfY810090	rogid:XzX0ccQ94dRfnwZ0gCAiLZZJ+HI9986	intact-crc:A938B856B7373E7F|rigid:z90eKTDaWJHQKEwuodEKzScehqk	false	glutathione s tranferase tag:?-?|necessary binding region:216-234	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ET78	uniprotkb:G1U2U3	intact:EBI-8350389|intact:MINT-4099221|uniprotkb:Q9ET79|uniprotkb:Q3U077|ensembl:ENSMUSP00000017961|ensembl:ENSMUSP00000105052	intact:EBI-10055313|ensembl:ENSOCUP00000023696	psi-mi:jph2_mouse(display_long)|uniprotkb:Jph2(gene name)|psi-mi:Jph2(display_short)|uniprotkb:Jp2(gene name synonym)|uniprotkb:Junctophilin type 2(gene name synonym)	psi-mi:g1u2u3_rabit(display_long)|uniprotkb:TRPC3(gene name)|psi-mi:TRPC3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Woo et al. (2009)	pubmed:19277847|imex:IM-23707	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10055373|imex:IM-23707-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067541.1|refseq:NP_001192005.1|refseq:XP_006500035.1|ensembl:ENSMUSG00000017817(gene)|ensembl:ENSMUST00000017961(transcript)|ensembl:ENSMUST00000109425(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0055024"(regulation of cardiac muscle tissue development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9ET78	ensembl:ENSOCUG00000009487(gene)|ensembl:ENSOCUT00000029876(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0033198"(response to ATP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005459(Transient receptor potential channel 3)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770	-	comment:mint|function:Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development	-	figure legend:5B and C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/12	2015/01/12	rogid:vs5IFdM0JlfwvmUcraIjKfxlfY810090	rogid:XzX0ccQ94dRfnwZ0gCAiLZZJ+HI9986	intact-crc:AE66492AD4244419|rigid:z90eKTDaWJHQKEwuodEKzScehqk	false	glutathione s tranferase tag:?-?|mutation decreasing interaction:216-216	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ET78	uniprotkb:G1U2U3	intact:EBI-8350389|intact:MINT-4099221|uniprotkb:Q9ET79|uniprotkb:Q3U077|ensembl:ENSMUSP00000017961|ensembl:ENSMUSP00000105052	intact:EBI-10055313|ensembl:ENSOCUP00000023696	psi-mi:jph2_mouse(display_long)|uniprotkb:Jph2(gene name)|psi-mi:Jph2(display_short)|uniprotkb:Jp2(gene name synonym)|uniprotkb:Junctophilin type 2(gene name synonym)	psi-mi:g1u2u3_rabit(display_long)|uniprotkb:TRPC3(gene name)|psi-mi:TRPC3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Woo et al. (2009)	pubmed:19277847|imex:IM-23707	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10055357|imex:IM-23707-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067541.1|refseq:NP_001192005.1|refseq:XP_006500035.1|ensembl:ENSMUSG00000017817(gene)|ensembl:ENSMUST00000017961(transcript)|ensembl:ENSMUST00000109425(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0055024"(regulation of cardiac muscle tissue development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9ET78	ensembl:ENSOCUG00000009487(gene)|ensembl:ENSOCUT00000029876(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0033198"(response to ATP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005459(Transient receptor potential channel 3)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770	-	comment:mint|function:Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development	-	figure legend:4B and C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/12	2015/01/12	rogid:vs5IFdM0JlfwvmUcraIjKfxlfY810090	rogid:XzX0ccQ94dRfnwZ0gCAiLZZJ+HI9986	intact-crc:AF23492AD4244419|rigid:z90eKTDaWJHQKEwuodEKzScehqk	false	glutathione s tranferase tag:?-?|sufficient binding region:143-234|mutation decreasing interaction:216-216|mutation decreasing interaction:222-222|mutation decreasing interaction:227-227	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9ET78	uniprotkb:G1U2U3	intact:EBI-8350389|intact:MINT-4099221|uniprotkb:Q9ET79|uniprotkb:Q3U077|ensembl:ENSMUSP00000017961|ensembl:ENSMUSP00000105052	intact:EBI-10055313|ensembl:ENSOCUP00000023696	psi-mi:jph2_mouse(display_long)|uniprotkb:Jph2(gene name)|psi-mi:Jph2(display_short)|uniprotkb:Jp2(gene name synonym)|uniprotkb:Junctophilin type 2(gene name synonym)	psi-mi:g1u2u3_rabit(display_long)|uniprotkb:TRPC3(gene name)|psi-mi:TRPC3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Woo et al. (2009)	pubmed:19277847|imex:IM-23707	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10055345|imex:IM-23707-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067541.1|refseq:NP_001192005.1|refseq:XP_006500035.1|ensembl:ENSMUSG00000017817(gene)|ensembl:ENSMUST00000017961(transcript)|ensembl:ENSMUST00000109425(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0055024"(regulation of cardiac muscle tissue development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9ET78	ensembl:ENSOCUG00000009487(gene)|ensembl:ENSOCUT00000029876(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0033198"(response to ATP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005459(Transient receptor potential channel 3)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770	-	comment:mint|function:Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/12	2015/01/12	rogid:vs5IFdM0JlfwvmUcraIjKfxlfY810090	rogid:XzX0ccQ94dRfnwZ0gCAiLZZJ+HI9986	intact-crc:DB6E8666CDC1D30B|rigid:z90eKTDaWJHQKEwuodEKzScehqk	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)